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Journal articles on the topic "WNA 350"

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Dundar, Ibrahim, Marina Krichevskaya, Atanas Katerski, Malle Krunks, and Ilona Oja Acik. "Photocatalytic Degradation of Different VOCs in the Gas-Phase over TiO2 Thin Films Prepared by Ultrasonic Spray Pyrolysis." Catalysts 9, no. 11 (2019): 915. http://dx.doi.org/10.3390/catal9110915.

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In this study, we deposited TiO2 thin films onto borosilicate glass by ultrasonic spray pyrolysis at 350 and 450 °C. The aim of study is to determine the effect of deposition temperature on photocatalytic activity of TiO2 thin films and to investigate the performance of TiO2 thin films on photocatalytic degradation of methyl tert-butyl ether (MTBE), acetone, acetaldehyde, and heptane as functions of different operating parameters. TiO2 thin films deposited at 350 and 450 °C have a thickness value of 190 and 330 nm, respectively. All as-prepared TiO2 films possess an anatase crystalline structure. According to the X-ray photon spectroscopy (XPS) study, the TiO2 thin film deposited at 350 °C showed a higher amount of oxygen vacancies and hydroxyl groups on the film surface after UV treatment. The aged-TiO2 thin film deposited at 350 °C showed a water contact angle (WCA) value of 0° after 10 min UV irradiation, showing superhydrophilic surface behavior. The TiO2 film deposited at 350 °C exhibited the highest amount of conversion of MTBE (100%). The results also showed that TiO2 films are capable of photocatalytic degradation of MTBE (100%) and acetaldehyde (approx. 80%) in humid air conditions and high airflow rate. The visible-light-activity of TiO2 thin films was tested with 5 ppm MTBE and acetone. TiO2 thin films deposited at 350 °C with a surface area of 600 cm2 showed 60% of MTBE and 33% of acetone degradation under VIS light.
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Lou, J. S., and J. Jankovic. "Essential tremor: Clinical correlates in 350 patients." Neurology 41, no. 2, Part 1 (1991): 234. http://dx.doi.org/10.1212/wnl.41.2_part_1.234.

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Saleh, Saleh S., and Hasan Zuhudi Abdullah. "Optimization and Characterization of Anatase Formed on Anodized Titanium in Phosphoric Acid." Materials Science Forum 840 (January 2016): 240–44. http://dx.doi.org/10.4028/www.scientific.net/msf.840.240.

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Titanium (Ti) is widely used in dental and orthopedic implants because of its good biocombatibility and high corrosion resistance. Titanium oxide (TiO2) has shown to exhibit strong physicochemical bonding between Ti implant and living bone because of its ability to induce bone-like apatite in a body environment. Ti is always coated by an oxide surface layer of 1.5-10 nm thickness. TiO2 crystalline structures; anatase and rutile present several distinctive features, such as photocatalytic behaviour, superhydrophilicity and biocompatible properties. Anodic oxidation is used to modify the surface of pure titanium in a phosphuric acid electrolyte in order to maximize and characterize the TiO2 anatase crystalline phase. In the present work, thick films of the anatase polymorph of TiO2 were formed on commercially pure Ti foil under potentials 200 V-350 V at current densities 40 and 60 mA/cm2 for 10 min. Multiple characterization techniques were used. Glancing angle X-ray diffraction (GAXRD) is used to obtain crystalline phases, field emission scanning electron microscope (FESEM) is used to obtain surface images and water contact angle (WCA) is used to obtain the wettability of the oxide surface. According to GAXRD results the intensity of the major peak increased with increasing applied voltage and current density while decrease with molar concentration. This means that the amount and/or crystallinity of anatase are/is influenced with these parameters. The coated oxides obtained small amount of anatase is comparing to films anodized in H2SO4 electrolyte. Which confirm that slower crystallization in H3PO4 than in H2SO4. FESEM images obtained that as the voltage increased, the film breaks down locally and results in a porous surface. The porosity and the pore size increase with the increasing voltage. The pore size diameter at 300V for 0.3 M can reach up to 1μm. As for WCA results the coated samples at higher voltages (250 V, 300 V and 350 V) and molar concentration 0.3 M have shown more hydrophilic surface, with sample anodized at 350 V at 0.3 M have the lowest contact angle, thus the highest surface energy. While samples anodized at 200 V voltage observed more hydrophobic surface with sample anodized at 200 V at 0.1 M have the lower wettability, thus the lowest surface energy.
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Troccoli, Alberto. "Climate and the development community." Weather 64, no. 1 (2009): 25–26. http://dx.doi.org/10.1002/wea.350.

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Aithal, Sreedevi, Venkatesh Aithal, Joseph Kei, and Alehandrea Manuel. "Effect of Negative Middle Ear Pressure and Compensated Pressure on Wideband Absorbance and Otoacoustic Emissions in Children." Journal of Speech, Language, and Hearing Research 62, no. 9 (2019): 3516–30. http://dx.doi.org/10.1044/2019_jslhr-h-18-0426.

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Objective This study investigated pressurized transient evoked otoacoustic emission (TEOAE) responses and wideband absorbance (WBA) in healthy ears and ears with negative middle ear pressure (NMEP). Method In this cross-sectional study, TEOAE amplitude, signal-to-noise ratio, and WBA were measured at ambient and tympanometric peak pressure (TPP) in 36 ears from 25 subjects with healthy ears (age range: 3.1–13.0 years) and 88 ears from 76 patients with NMEP (age range: 2.0–13.1 years), divided into 3 groups based on NMEP (Group 1 with TPP between −101 and −200 daPa, Group 2 with TPP between −201 and −300 daPa, and Group 3 with TPP between −301 and −400 daPa). Results Mean TEOAE amplitude, signal-to-noise ratio, and WBA were increased at TPP relative to that measured at ambient pressure between 0.8 and 1.5 kHz. Further decrease in TPP beyond −300 daPa did not result in further increases in the mean TEOAE or WBA at TPP. The correlation between TEOAE and WBA was dependent on the frequency, pressure conditions, and subject group. There was no difference in pass rates between the 2 pressure conditions for the control group, while the 3 NMEP groups demonstrated an improvement in pass rates at TPP. With pressurization, the false alarm rate for TEOAE due to NMEP was reduced by 17.8% for NMEP Group 1, 29.2% for NMEP Group 2, and 15.8% for NMEP Group 3. Conclusion Results demonstrated the feasibility and clinical benefits of measuring TEOAE and WBA under pressurized conditions. Pressurized TEOAE and WBA should be used for assessment of ears with NMEP in hearing screening programs to reduce false alarm rates.
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Spectre, Galia, Lisa Arnetz, Claes-Göran Östenson, Kerstin Brismar, Nailin Li, and Paul Hjemdahl. "Twice daily dosing of aspirin improves platelet inhibition in whole blood in patients with type 2 diabetes mellitus and micro- or macrovascular complications." Thrombosis and Haemostasis 106, no. 09 (2011): 491–99. http://dx.doi.org/10.1160/th11-04-0216.

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SummaryThe efficacy of low-dose aspirin in type 2 diabetes mellitus (T2DM) has been questioned. We tested if twice daily dosing of aspirin would be more effective in T2DM, possibly due to increased platelet turnover. A randomised cross-over study compared 75 mg aspirin OD, 75 mg BID and 320 mg OD (≥2 week treatment periods) in 25 patients with T2DM and micro- or macrovascular complications. Platelet responses were examined by impedance aggregometry (WBA) and the IMPACT-R aspirin test in whole blood, light transmittance aggregometry in plateletrich plasma (LTA), and urinary 11-dehydro-thromboxane B2 (TxM). Aspirin 75 mg BID decreased arachidonic acid (AA)-induced WBA compared to 75 mg OD (9.7 ± 4.5 vs. 12.6 ± 3.5 ohm; p=0.003) or to 320 mg OD (11.5 ± 4.2 Ohms; p=0.049). WBA responses to collagen were similarly attenuated by BID or high dosing (by 12–14%; p=0.02 for both). The IMPACT-R showed a better response to 75 mg BID compared to 75 mg OD (p=0.049), but not to 320 mg OD. AA-induced aggregation by LTA was <6.5% on all occasions, with no differences between aspirin dosages. TxM was reduced after 320 mg OD (p=0.002), but not 75 mg BID (p=0.07). Reticulated platelets were highly correlated with mean platelet volume (MPV; r2=0.74, p<0.0001). Both markers for platelet turnover were correlated with AA-induced WBA, but neither identified patients who benefited from BID dosing dependably. In conclusion, twice daily dosing improved laboratory responses to aspirin in high risk T2DM patients. Studies of whether BID dosing of aspirin can improve clinical outcomes in such patients are of interest.
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Yang, Yu Sen, Ting Pin Cho, and Jia Hau Lin. "Annealing Effects on Hydrophobic AlN Coatings." Applied Mechanics and Materials 284-287 (January 2013): 276–80. http://dx.doi.org/10.4028/www.scientific.net/amm.284-287.276.

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The effects of annealing at various annealing temperature on hydrophobic AlN coatings were investigated. AlN coatings were deposited in Ar/N2 plasma by using reactive magnetron sputtering process. Two medium frequency (MF) powered Al targets were used. AlN coatings were annealed in air at 300°C, 600°C, 700°C, 800°C, 900°C, 1000°C and 1100°C, respectively. The hydrophobic and hydrophilic properties were evaluated by using water contact angle (WCA) measurement. Microstructure and morphology were observed using X-ray diffraction (XRD), scanning electron microscopy (SEM) and X-ray Photoelectron Spectrometer (XPS), respectively. According to the results revealed by XRD and SEM, AlN possess hexagonal close-packed (hcp) structures and good crystallization. The morphology of AlN coating after annealing at 800°C is still similar to the as-deposited AlN coating. As the annealing temperature increases to 1000°C, the XRD peaks of Al2O3 phase can be clearly identified. The main XRD peaks of the AlN coatings still can be found after annealing at 1100°C. The as-deposited AlN coating exhibits hydrophobic behavior and the highest WCA of 119°. As the annealing temperature increases to 300°C, the WCA decreases sharply to 77°. The lower WCA of AlN coatings obtained after annealing is related to the Al2O3 thin films upon AlN coatings.
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Ambrose, Christopher S., Xiaohui Jiang, and Kunjana Mavunda. "737. The Prevalence of Diagnosed Chronic Lung Disease in US Infants by Gestational Age: Implications for RSV Policy." Open Forum Infectious Diseases 5, suppl_1 (2018): S264—S265. http://dx.doi.org/10.1093/ofid/ofy210.744.

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Abstract Background Perinatal chronic lung disease (CLD), previously referred to as bronchopulmonary dysplasia (BPD), is associated with preterm birth and occurs rarely among term infants. Children with CLD are at elevated risk for severe RSV disease in the first 2 years of life. Definitions of CLD/BPD identify infants who require supplemental oxygen at 28 days of life or 36 weeks postmenstrual age, with no restriction by gestational age (GA) at birth. However, the AAP Committee on Infectious Disease guidance does not recommend RSV immunoprophylaxis for infants with CLD born at ≥32 weeks gestational age (wGA), even though infants with CLD/BPD up to 41 wGA were included in pivotal efficacy studies. This study determined the prevalence of diagnosed CLD in US infants as a function of wGA at birth and the number of infants with CLD born at ≥32 wGA. Methods The Kids’ Inpatient Database (KID) is a nationally representative survey conducted every 3 years in the United States. Birth hospitalization data from KID were utilized to estimate the prevalence of CLD (ICD-9 = 770.7) among US infants in 2003–2012 overall and as a function of coincident codes for GA (ICD-9 = 765.21–765.29, reported in 2-week intervals). The prevalence of CLD among 32 wGA infants was imputed based on the distribution of CLD cases as a function of wGA. KID data from 2015 were not available due to the transition to ICD-10 coding. Results A total of 31,984 infants had a CLD diagnosis across the 4 years, representing 0.2% of US births. The prevalence of CLD declined from 20.8 to 19.5 per 10,000 between 2003 and 2012. Of those, 25,554 infants with CLD (80%) had GA coded in the database. The percentage of CLD infants born at <27 wGA increased from 44% in 2003 to 52% in 2012, whereas the percentage at ≥29 wGA decreased from 27% to 21% (figure). Overall, the percentages born at 31–32, 33–34, and >34 wGA were 5.7%, 2.2%, and 1.2%, respectively. An estimated 5.7% of infants with CLD were born at ≥32 wGA, representing 0.9 of every 10,000 US births or ~350 infants annually. Conclusion Fewer than 400 infants are born at ≥32 wGA and diagnosed with CLD annually in the United States. The rationale for excluding this small but high-risk group of infants from the population recommended for RSV immunoprophylaxis is not clear. Funded by AstraZeneca :Disclosures. C. S. Ambrose, AstraZeneca: Employee, Salary and Stocks. X. Jiang, EpiStat Institute: Employee, Consulting fee and Salary. AstraZeneca: Consultant, Consulting fee. K. Mavunda, AstraZeneca: Speaker’s Bureau, Speaker honorarium.
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Anshar, Andi Muhammad, Sengo Kobayashi, and Satoshi Okano. "Effect of Heat Treatments on Wettability of Nacre." Materials Science Forum 985 (April 2020): 86–90. http://dx.doi.org/10.4028/www.scientific.net/msf.985.86.

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The surface wettability of biomaterials influences on osteoblast behavior and bone formation. In this research, the variation of wettability of nacre by heat treatments was examined. Plates of the nacre were fabricated from shells of the Akoya pearl oyster. The specimens were heated at 100, 200, 300, 400, 500, and 600 °C. Characterizations of the specimens during and after heat treatments were carried out using scanning electron microscopy, X-ray diffractometry, and thermogravimetry-differential thermal analysis. The water contact angle (WCA) of the specimen was measured to evaluate wettability. The color of nacre changed from iridescent color to brownish weak-iridescence by the heating at and over 300 °C. The nacre heated at and over 300 °C became brittle because organic substances in nacre, which acts as the glue between the aragonite platelets were evaporated by the heating. The WCA of the specimen was decreased with increasing heating temperature, which should be related to the decrease in the number of organic substances in nacre by the heating.
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Byker, Holly P., Nader Soltani, Darren E. Robinson, François J. Tardif, Mark B. Lawton, and Peter H. Sikkema. "Control of glyphosate-resistant Canada fleabane [Conyza canadensis (L.) Cronq.] with preplant herbicide tankmixes in soybean [Glycine max. (L). Merr.]." Canadian Journal of Plant Science 93, no. 4 (2013): 659–67. http://dx.doi.org/10.4141/cjps2012-320.

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Byker, H. P., Soltani, N., Robinson, D. E., Tardif, F. J., Lawton, M. B. and Sikkema, P. H. 2013. Control of glyphosate-resistant Canada fleabane [ Conyza canadensis (L.) Cronq.] with preplant herbicide tankmixes in soybean [ Glycine max . (L). Merr.]. Can. J. Plant Sci. 93: 659–667. Glyphosate previously provided excellent control of Canada fleabane; however, with the evolution of glyphosate-resistant (GR) Canada fleabane in Ontario, alternative herbicides must be identified for control of this weed in soybean. The objective of this study was to identify preplant herbicide tankmixes that provide effective control of GR Canada fleabane. A total of 12 field trials were completed over a 2-yr period (2011, 2012) in fields previously confirmed with GR Canada fleabane. Preplant tankmixes of glyphosate (900 g a.e. ha−1) plus saflufenacil (25 g a.i. ha−1) or saflufenacil/dimethenamid-p (245 g a.i. ha−1) provided greater than 87% control 4 wk after application (WAA) across all sites. Glyphosate (900 g a.e. ha−1) tankmixed with metribuzin (1120 g a.i. ha−1), cloransulam-methyl (35 g a.i. ha−1) or flumetsulam (70 g a.i. ha−1) provided 78 to 99% control 8 WAA. Control of GR Canada fleabane prior to soybean emergence is essential as currently there are no herbicides that provide acceptable control in-crop. Because of the lack of in-crop options, spring residual herbicides may be required for season long control in regions where Canada fleabane emerges throughout the year to reduce Canada fleabane seed production and populations in subsequent years.
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Dissertations / Theses on the topic "WNA 350"

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Renner, Swen Christoph. "Structure and diversity of cloud forest bird communities in Alta Verapaz, Guatemala, and implications for conservation." Doctoral thesis, [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969959478.

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Bayoudh, Aïcha Souami Lakhdar. "Récit et discours dans le Kitāb al-imtāʻ wa-al-muʼānasa d'Abū Ḥayyān at-Tawḥīdī, 310-320/922-932 - 414/1023 /". Lille : Atelier national de reproduction des thèses, 2007. http://catalogue.bnf.fr/ark:/12148/cb411537861.

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Bayoudh, Aïcha. "Récit et discours dans le Kitāb al-imtāʾwa l-muʾānasa d'Abū Ḥayyān at-Tawḥīdī (310-320/922-932 - 414/1023)". Paris 3, 2003. http://www.theses.fr/2003PA030147.

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Le savoir commun est une source de communication dans l'existence quotidienne. Il l'est plus particulièrement dans les cercles intellectuels du IV/X s. Il était donc indispensable pour l'homme de lettres d'y participer pour combler son besoin de discussion et pour affirmer sa notoriété intellectuelle parmi ses émules. Pour Abû Hayyân at-Tawhîdî, il suffit de dépasser les obstacles de discrimination socio-culturelle et religieuse pour révéler un esprit libre, déterminé à dénoncer le mal pour instaurer le bien. De toute évidence, son but est éducatif. Il est clair ensuite que le rôle de l'élite intellectuelle est de s'interroger sur tous les phénomènes de la vie pour servir la sagesse et répandre l'éthique. C'est ce qui permet d'instaurer un équilibre parfait entre la passion et la raison. Or, une telle tâche ne peut se réaliser que par l'exploitation d'un langage conforme aux messages visés. Pour cela, il faut se servir d'une méthode adéquate aux circonstances de la communication. C'est ainsi que dans l'Imtâ' wa l-mu'ânasa, at-Tawhîdî procède à retranscrire les idéologies communes dans une perspective de production littéraire déterminée par le principe du discours et du récit. Faut-il voir dans cette méthode un acte de transmission destiné à l'exploration ?<br>Shared knowledge is a source of communication in the bayly life. This was particulary the case in intellectual circles in the IV/X th. Centuries, and was an essential part of life for men of letters at that time in order tout fulfil their need for discussion and establish their intellectual reputations among their acolytes. For Abû Hayyân at-Tawhîdî, overcoming the obstacle of soiocultural and religious discrimination was sufficient to reveal a free spirit, one determined to demounce evil and enshrine good. It seems his objective was educational. Ii's clear subsequently that the role of the intellectual elite is to inquire into the phenomena of life in order to serve wisdom and disseminate ethics. It is this that makes in possible to establish a perfect balance between passion and reason. Yet such a goal could only be ashieved using language that corresponded to the message. To this end, it was nacessary to to employ a method adapted to the circumstances of communication. Thus in al-Imtâ' wa l-mu'ânasa, at-Tawhîdî proceeded to retranscribe commonideologies in the course of a literary production thet was determined by the principal of discourse and narration. Should this method be viewed as an act of transmission aimed at exploration ?
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Wu, Mingfu. "A novel non-canonical WNT pathway regulates the asymmetric b cell division in Caenorhabditis elegans." Diss., Kansas State University, 2005. http://hdl.handle.net/2097/355.

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Doctor of Philosophy<br>Department of Biology<br>Michael A. Herman<br>The polarities of several cells that divide asymmetrically during C. elegans development are controlled by Wnt signaling. LIN-44/Wnt and LIN-17/Fz control the polarities of cells in the tail of developing C. elegans larvae, including the male-specific blast cell, B, which divides asymmetrically to generate a larger anterior daughter and a smaller posterior daughter. We determined that the canonical Wnt pathway components are not involved in the control of B cell polarity. However, POP-1/Tcf is involved and asymmetrically distributed to B daughter nuclei. Aspects of the B cell division are reminiscent of the divisions controlled by the planar cell polarity (PCP) pathway that has been described in both Drosophila and vertebrate systems. We identified C. elegans homologs of Wnt/PCP components and have determined that many of them appear to be involved in the regulation of B cell polarity and POP-1 asymmetric distribution to B daughter nuclei. Thus a non-canonical Wnt pathway, which is different from other Wnt pathways in C. elegans, but similar to the PCP pathways, appears to regulate B cell polarity. Molecular mechanisms of this PCP pathway were also investigated. We determined that LIN-17/Fz is asymmetrically distributed to the B cell cortex prior to, during, and after, division. Furthermore, the asymmetric localization of LIN-17::GFP is controlled by LIN-44/Wnt and MIG-5/Dsh. The cysteine rich domain (CRD), seven trans-membrane domain and KTXXXW motif of LIN-17 are required for LIN-17 to rescue lin-17, while only seven trans-membrane domains and KTXXXW motif are required for LIN-17 asymmetric localization. MIG-5::GFP asymmetrically localized to the B cell prior to and after division in a LIN-17/Fz dependent manner. We examined the functions of these MIG-5 domains. The DEP domain is required for MIG-5 membrane association, while the PDZ domain is responsible for different levels of MIG-5 in the B daughters. The DEP and PDZ domain are required to rescue B cell polarity defect of mig-5 males, while the DIX domain is not that important. In summary, a novel PCP-like pathway, in which LIN-17 and MIG-5 are asymmetrically localized, is conserved in C. elegans and involved in the regulation of B cell polarity.
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Nakamura, Rei. "Investigation of the Role of Muller Glia-Derived Dickkopf3 (Dkk3) during Retinal Degeneration." Scholarly Repository, 2009. http://scholarlyrepository.miami.edu/oa_dissertations/310.

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Retinal degeneration is characterized by the irreversible loss of photoreceptors. A key research question is the identification and characterization of photoreceptor protective factors that prevent or delay vision loss. The Wnt pathway is a critical cellular communication pathway involved in development and diseases of the central nervous system (CNS). Recently, we discovered that multiple components of the Wnt pathway were differentially expressed in the rd1 mouse model of retinal degeneration. One of the most highly upregulated genes was Dickkopf3 (Dkk3), a secreted Wnt pathway protein of unknown function. Additionally, we demonstrated that Wnt signaling is neuroprotective in primary retinal culture (Yi et al., 2007). These data led to the hypothesis that Dkk3 is a regulator of Wnt-mediated neuroprotection during retinal degeneration. The role of Dkk3 in the retina and its activity in the Wnt pathway was identified in this dissertation project using a series of biochemical, molecular and cell biology methodologies. First, Dkk3 was shown to be expressed and secreted from Muller glia in mouse retinal tissue and primary Muller glia culture. I then demonstrated that Muller glia are a Wnt-responsive cell type and that Dkk3 potentiates Wnt3a-mediated signaling. Interestingly, the latter effect was not observed in other cell types in the retina such as retinal ganglion cells and retinal pigmented epithelial cells. Thus, Dkk3 may act on Muller glia to positively modulate Wnt signaling during retinal degeneration, which could potentially amplify the neuroprotective activity of the Wnt pathway. Next, the role of Dkk3 in cellular viability was explored. HEK293 cells stably expressing Dkk3 were shown to be significantly protected from staurosporine-induced apoptosis compared with vector control. This result suggests that Dkk3 may mediate a direct pro-survival effect onto photoreceptors during retinal degeneration. Protein interaction experiments demonstrated that Dkk3 formed a complex with the single pass transmembrane proteins Krm1 and Krm2 in the membrane, potentially in the endoplasmic reticulum (ER). Furthermore, Wnt signaling luciferase reporter assays demonstrated that Krm2, but not Krm1, abolished Dkk3-mediated Wnt3a potentiation. These data suggest that Dkk3 modulates Wnt signaling by antagonizing Dkk1-Krm dependent Wnt inhibition. Further studies will determine whether this activity is sufficient for the potentiation of Wnt signaling by Dkk3. Lastly, co-immunoprecipitation followed by mass spectrometry analysis was used to identify a novel interacting protein of Dkk3. Dkk3 was shown to interact with glucose response protein 78 (GRP78), an ER-resident chaperone. This suggested that Dkk3 protein is part of the unfolded protein response through GRP78 in the ER. In conclusion, these studies identified two novel functions of Dkk3 in regulating Wnt signaling pathway and cellular viability and suggest a physiological role for Dkk3 and Wnt signaling during retinal degeneration. Future studies will explore the significance of Dkk3-Krm and Dkk3-GRP78 interactions in the retina. Further, elucidation of the regulation of Dkk3 and other Wnt ligands in the ER and the consequence of ER stress on the biological activity of Wnt signaling will provide a better understanding of the role of the Wnt pathway during retinal degeneration.
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Ataman, Bulent. "The Molecular Mechanisms of Activity-Dependent Wingless (Wg)/Wnt Signaling at a Drosophila Glutamatergic Synapse: a Dissertation." eScholarship@UMMS, 2008. https://escholarship.umassmed.edu/gsbs_diss/353.

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Synaptic plasticity, the ability of synapses to change in strength, underlies complex brain functions such as learning and memory, yet little is known about the precise molecular mechanisms and downstream signaling pathways involved. The major goal of my doctoral thesis was to understand these molecular mechanisms and cellular processes underlying synaptic plasticity using the Drosophilalarval neuromuscular junction (NMJ) as a model system. My work centered on a signaling pathway, the Wg/Wnt signaling pathway, which was found to be crucial for activity-driven synapse formation. The Wg/Wnt family of secreted proteins, besides its well-characterized roles in embryonic patterning, cell growth and cancer, is beginning to be recognized as a pivotal player during synaptic differentiation and plasticity in the brain. At the DrosophilaNMJ, the Wnt-1 homolog Wingless (Wg) is secreted from presynaptic terminals and binds to Frizzled-2 (DFz2) receptors in the postsynaptic muscle. Perturbations in Wg signaling lead to poorly differentiated NMJs, containing synaptic sites that lack both neurotransmitter release sites and postsynaptic structures. In collaboration with other members of the Budnik lab, I set out to unravel the mechanisms by which Wg regulates synapse differentiation. We identified a novel transduction pathway that provides communication between the postsynaptic membrane and the nucleus, and which is responsible for proper synapse development. In this novel Frizzled Nuclear Import (FNI) pathway, the DFz2 receptor is internalized and transported towards the nucleus. The C-terminus of DFz2 is subsequently cleaved and imported into the postsynaptic nucleus for potential transcriptional regulation of synapse development (Mathews, Ataman, et al. Science (2005) 310:1344). My studies also centered on the genetic analysis of Glutamate Receptor (GluR) Interacting Protein (dGRIP), which in mammals has been suggested to regulate the localization of GluRs and more recently, synapse development. I generated mutations in the gene, transgenic strains carrying a dGRIP-RNAi and fluorescently tagged dGRIP, and antibodies against the protein. Remarkably, I found dgrip mutants had synaptic phenotypes that closely resembled those in mutations altering the FNI pathway. Through the genetic analysis of dgrip and components of the FNI pathway, immunoprecipitation studies, electron microscopy, in vivotrafficking assays, time-lapse imaging, and yeast two-hybrid assays, I demonstrated that dGRIP had a hitherto unknown role as an essential component of the FNI pathway. dGRIP was found in trafficking vesicles that contain internalized DFz2. Further, DFz2 and dGRIP likely interact directly. Through the use of pulse chase experiments I found that dGRIP is required for the transport of DFz2 from the synapse to the nucleus. These studies thus provided a molecular mechanism by which the Wnt receptor, DFz2, is trafficked from the postsynaptic membrane to the nucleus during synapse development and implicated dGRIP as an essential component of the FNI pathway (Ataman et al. PNAS (2006) 103:7841). In the final part of my dissertation, I concentrated on understanding the mechanisms by which neuronal activity regulates synapse formation, and the role of the Wnt pathway in this process. I found that acute changes in patterned activity lead to rapid modifications in synaptic structure and function, resulting in the formation of undifferentiated synaptic sites and to the potentiation of spontaneous neurotransmitter release. I also found that these rapid modifications required a bidirectional Wg transduction pathway. Evoked activity induced Wg release from synaptic sites, which stimulated both the postsynaptic FNI pathway, as well as an alternative presynaptic Wg pathway involving GSK-3ß/Shaggy. I suggest that the concurrent activation of these alternative pathways by the same ligand is employed as a mechanism for the simultaneous and coordinated assembly of the pre- and postsynaptic apparatus during activity-dependent synapse remodeling (Ataman et al. Neuron (2008) in press). In summary, my thesis work identified and characterized a previously unrecognized synaptic Wg/Wnt transduction pathway. Further, it established a mechanistic link between activity-dependent synaptic plasticity and bidirectional Wg/Wnt signaling. These findings provide novel mechanistic insight into synaptic plasticity.
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Lai, Wan Teng [Verfasser]. "We come. We work. We relate. The migrant labourers in Penang / Wan Teng Lai." Bonn : Universitäts- und Landesbibliothek Bonn, 2017. http://d-nb.info/1149050748/34.

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Welsing, Marcel [Verfasser]. "Die Vorgaben des Art. 57 WSA und die konstitutionellen Verfassungen der thüringischen Staaten / Marcel Welsing." Baden-Baden : Nomos Verlagsgesellschaft mbH & Co. KG, 2016. http://d-nb.info/1106337816/34.

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Liu, Wan-hsin [Verfasser]. "Determinants of Industrial Innovation in China and the Role of University Research / Wan-Hsin Liu." Kiel : Universitätsbibliothek Kiel, 2012. http://d-nb.info/102748865X/34.

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Henry, Julia, та Thomas Fischer. "التوعية الصحية للمراة - alhaml, alwilada wa nifass: الحمل,الولادة والنفاس - Atawiaa asihia lelmaraa". Zentrum für Forschung, Weiterbildung und Beratung (ZFWB) an der ehs Dresden gGmbH, Dresden, 2020. https://slub.qucosa.de/id/qucosa%3A75298.

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Die Broschüre ist ein Ergebnis des Projektes 'Gesundheitskompetenz für Migrantinnen und Migranten', gefördert durch das Sächsische Staatsministerium für Soziales und Gesellschaftlichen Zusammenhang. Das Projekt wurde durchgeführt durch die Zentrum für Forschung, Beratung und Weiterbildung an der Evangelischen Hochschule Dresden gGmbH. Basierend auf verschiedenen wissenschaftlichen Erhebungen wurde dabei der Edukationsbedarf im Hinblick auf Schwangerschaft, Geburt und Wochenbett bei Arabisch sprechenden geflüchteten Frauen ermittelt. Zielgruppe der Publikation sind Multiplikatoren ('Peers') sowie Arabisch sprechende Frauen und deren Familien. Sie enthält laiengerecht aufbereitete Informationen Schwangerschaft, Geburt, Wochenbett und seelischer Gesundheit in der Schwangerschaft. Die Broschüre ist in arabischer Sprache verfasst. Eine identische deutsche Sprachfassung liegt ebenfalls vor.
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Books on the topic "WNA 350"

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Gu wan bao zhai 300 qi xuan. Wen hui chu ban she, 2003.

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Nakkhāo 3.0 čhōt hin sư̄ Thai: Wan nakkhāo 5 Mīnākhom 2553. Samākhom Nakkhāo Naknangsư̄phim hǣng Prathēt Thai, 2010.

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Yue wan yue kai kuo de 300 ge si wei you xi. Jiang xi mei shu chu ban she, 2011.

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Editto, Tatora, ed. Minecraft mi ji da bai ke: Wan chu qian neng de 320 zhao ji qiao. Cheng bang wen hua shi ye gu fen you xian gong si, 2017.

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Hafo Niujin xue sheng zui ai wan de 300 ge chuang yi si wei you xi. Jiangsu feng huang mei shu chu ban she, 2015.

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Ren lei jian shi: Wo men zhe 300 wan nian = Human brief history : our 3 million years. Wu han da xue chu ban she, 2006.

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Wan wei you mo: Jiang shu gu shi hui zui hao xiao de gu shi 300 ze = Wanweiyoumo. Shanghai wen yi chu ban she, 2003.

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Guo min 305 wen: Zui shen ru, wan zheng de yi liao xin zhi = Allergies at your fingertips. Yuan shui wen hua, 2000.

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Tom, Fahey, and Savage Wendy, eds. Gao xue ya 305 wen: Zui shen ru, wan zheng de yi liao xin zhi = High blood pressure at your fingertips. Yuan shui wen hua, 2000.

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Zhuan cai wan yong shi dian: She ji shi bi zhi zhuan cai xuan da, feng ge su zao, shi gong bu zhou, tian feng gong fa 350 = Tile material. Cheng bang wen hua shi ye gu fen you xian gong si, 2015.

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Book chapters on the topic "WNA 350"

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Katondo, Richard J. M., and Agnes M. S. Nyomora. "The role of ecosystem services in enhancing climate change resilience of local communities: the case of Ngarambe-Tapika Wildlife Management Area, Rufiji district, Tanzania." In Climate change impacts and sustainability: ecosystems of Tanzania. CABI, 2020. http://dx.doi.org/10.1079/9781789242966.0169.

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Abstract This study examined the role of ecosystem services in enhancing climate change resilience of local communities in Ngarambe-Tapika Wildlife Management Area (WMA). The study aimed to identify forms of ecosystem services that can be gained from conservation of a WMA in relation to climate change adaptation. The design for this study adopted both a quantitative and a qualitative research approach. The study was undertaken in Ngarambe-Tapika WMA located between latitude 39° S and 39°30' S and between longitude 12°30' E and 13° E. It is located alongside the north-eastern border of the Selous Game Reserve. The area is also the home of local people whose lifestyles and livelihoods are intricately tied to the biological diversity and the functioning of this natural system. Purposive sampling was employed in selecting respondents for the household questionnaire, focus group discussions and key informant interviews. This study found that income obtained from Ngarambe-Tapika ecosystems by the communities were invested in material welfare and livelihoods that enhance resilience to climate change, primarily social services (54.9%) such as construction of houses, dispensaries and rehabilitation of the primary schools, and some of the money was spent on electricity provision for the community and energy for light and water pumps. Other benefits included employment (16.5%), protection from dangerous and problematic wildlife (14.3%) and petty business (14.3%). Generally, in Ngarambe-Tapika WMA there is a need to emphasize conservation awareness and extension programmes which advocate sustainable utilization of wildlife resources, and adopt an integrated approach of climate-smart agriculture to address the challenges related to food insecurity and climate change and variability. The latter would enable increased agricultural productivity to support equitable increases in farm incomes, improve food security and build resilience of agricultural and food security systems to adapt to climate change and variability.
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"Marine Artificial Reef Research and Development: Integrating Fisheries Management Objectives." In Marine Artificial Reef Research and Development: Integrating Fisheries Management Objectives, edited by Stephen C. Schroeter, Daniel C. Reed, and Peter Raimondi. American Fisheries Society, 2018. http://dx.doi.org/10.47886/9781934874516.ch12.

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&lt;em&gt;Abstract&lt;/em&gt;.—The Wheeler North Reef (WNR) is a large (70.4 ha [174 acre]) artificial reef in Southern California designed to mitigate the loss of kelp forest habitat and its associated community of algae, invertebrates, and fishes caused by the operation of the San Onofre Nuclear Generating Station (SONGS). Conditions of the SONGS’ operating permit require that the success of WNR in compensating for the kelp forest resources destroyed by the 30 years of the power plant’s operations be determined by long-term monitoring that is independent of the owners of SONGS. Performance standards pertaining to physical and ecological attributes of WNR are used as a basis for determining the success of WNR in meeting the mitigation objective to replace kelp forest resources in kind. We discuss details of the sampling design, evaluation criteria, and monitoring results and show how they are used to inform adaptive management that helps to ensure that the mitigation goals are met.
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Nirmala, M. Baby. "A Survey of Big Data Analytics Systems." In Big Data. IGI Global, 2016. http://dx.doi.org/10.4018/978-1-4666-9840-6.ch046.

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In this emerging era of analytics 3.0, where big data is the heart of talk in all sectors, achieving and extracting the full potential from this vast data is accomplished by many vendors through their new generation analytical processing systems. This chapter deals with a brief introduction of the categories of analytical processing system, followed by some prominent analytical platforms, appliances, frameworks, engines, fabrics, solutions, tools, and products of the big data vendors. Finally, it deals with big data analytics in the network, its security, WAN optimization tools, and techniques for cloud-based big data analytics.
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Nirmala, M. Baby. "A Survey of Big Data Analytics Systems." In Advances in Data Mining and Database Management. IGI Global, 2014. http://dx.doi.org/10.4018/978-1-4666-5864-6.ch016.

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In this emerging era of analytics 3.0, where big data is the heart of talk in all sectors, achieving and extracting the full potential from this vast data is accomplished by many vendors through their new generation analytical processing systems. This chapter deals with a brief introduction of the categories of analytical processing system, followed by some prominent analytical platforms, appliances, frameworks, engines, fabrics, solutions, tools, and products of the big data vendors. Finally, it deals with big data analytics in the network, its security, WAN optimization tools, and techniques for cloud-based big data analytics.
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"Locations That Are Beneficial for Voices and Improve Them, and Those That Diminish and Spoil Them [fols. 35a–35b; ZY 44]". У Ḥāwī l-Funūn wa-Salwat al-Maḥzūn, Encompasser of the Arts and Consoler of the Grief-Stricken by Ibn al-Ṭaḥḥān. BRILL, 2021. http://dx.doi.org/10.1163/9789004465497_032.

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Loreta Paun, Diana, and Alexandra Mirica. "Pheochromocytomas and Paragangliomas: Genotype-Phenotype Correlations." In Pheochromocytoma, Paraganglioma and Neuroblastoma. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.95888.

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Pheochromocytomas and paragangliomas are rare neuroendocrine tumors, with genetic background in about 40% of cases, involving more than 30 susceptibility genes. The susceptibility genes can be divided into three main molecular clusters: pseudohypoxic, kinase signaling, and Wnt signaling. Biochemical characterization of these particular tumors should be integrated into the diagnostic algorithm because it can help apply personalized medicine principles and targeted therapy. These tumors can present with very different genotype-phenotype correlations, and their characterization can help the clinical practitioner make optimal clinical management decisions and prioritize genetic testing. This chapter summarizes the most important aspects of genetics and clinical characteristics, together with new genotype-phenotype correlation data.
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Pabona, JMP, FA Simmen, MA Nikiforov, D. Zhuang, LC Giudice, and RCM Simmen. "Wnt Antagonist DKK1 Is a Target of Krüppel-Like Factor 9 (KLF9) in Endometrial Stromal Cells: Implications for Uterine Receptivity." In The Endocrine Society's 92nd Annual Meeting, June 19–22, 2010 - San Diego. Endocrine Society, 2010. http://dx.doi.org/10.1210/endo-meetings.2010.part3.p8.p3-357.

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González-García, Samuel, Aída Hamdan-Partida, Anaíd Bustos-Hamdan, and Jaime Bustos-Martínez. "Factors of Nasopharynx that Favor the Colonization and Persistence of Staphylococcus aureus." In Pharynx - Diagnosis and Treatment. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.95843.

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Between 30 and 50% of the world population is permanently colonized in some anatomical site by Staphylococcus aureus, although the vast majority are asymptomatic carriers. The nose is its main niche and currently the colonization of S. aureus in the pharynx has become relevant due to the variety of reported carrier rates and the epidemiological importance of the dissemination of Methicillin-resistant S. aureus strains (MRSA) by pharyngeal carriers. For this bacterium to colonize a tissue successfully, it is necessary to establish many interactions with bacterial and host cell components such as bacterial wall teichoic acids (WTA) with the Scavenger SREC-1 host receptor and at the same time evade the defense mechanisms. On the other hand, there are host factors that will facilitate or complicate the colonization or persistence of S. aureus at these sites, such as physiological, genetic, immunological and microbiological factors.
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Wakabayashi, John. "Field and petrographic reconnaissance of Franciscan complex rocks of Mount Diablo, California: Imbricated ocean floor stratigraphy with a roof exhumation fault system." In Regional Geology of Mount Diablo, California: Its Tectonic Evolution on the North America Plate Boundary. Geological Society of America, 2021. http://dx.doi.org/10.1130/2021.1217(09).

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ABSTRACT Franciscan subduction complex rocks of Mount Diablo form an 8.5 by 4.5 km tectonic window, elongated E-W and fault-bounded to the north and south by rocks of the Coast Range ophiolite and Great Valley Group, respectively, which lack the burial metamorphism and deformation displayed by the Franciscan complex. Most of the Franciscan complex consists of a stack of lawsonite-albite–facies pillow basalt overlain successively by chert and clastic sedimentary rocks, repeated by faults at hundreds of meters to &amp;lt;1 m spacing. Widely distributed mélange zones from 0.5 to 300 m thick containing high-grade (including amphibolite and eclogite) assemblages and other exotic blocks, up to 120 m size, form a small fraction of exposures. Nearly all clastic rocks have a foliation, parallel to faults that repeat the various lithologies, whereas chert and basalt lack foliation. Lawsonite grew parallel to foliation and as later grains across foliation. The Franciscan-bounding faults, collectively called the Coast Range fault, strike ENE to WNW and dip northward at low to moderate average angles and collectively form a south-vergent overturned anticline. Splays of the Coast Range fault also cut into the Franciscan strata and Coast Range ophiolite and locally form the Coast Range ophiolite–Great Valley Group boundary. Dip discordance between the Coast Range fault and overlying Great Valley Group strata indicates that the northern and southern Coast Range fault segments were normal faults with opposite dip directions, forming a structural dome. These relationships suggest accretion and fault stacking of the Franciscan complex, followed by exhumation along the Coast Range fault and then folding of the Coast Range fault.
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"Food and Drinks That Are Beneficial to the Throats and Those That Are Not [fols. 34a–35a; ZY 43–4]". У Ḥāwī l-Funūn wa-Salwat al-Maḥzūn, Encompasser of the Arts and Consoler of the Grief-Stricken by Ibn al-Ṭaḥḥān. BRILL, 2021. http://dx.doi.org/10.1163/9789004465497_031.

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Conference papers on the topic "WNA 350"

1

Mechera, Robert, Simone Münst, Silvio Däster, et al. "Abstract 350: Pregnancy at early age is associated with a reduction of progesterone-responsive cells and epithelial Wnt signaling in human breast tissue." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-350.

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Clark, Bruce J., and Marc J. Rogoff. "Economic Feasibility of a Plasma Arc Gasification Plant, City of Marion, Iowa." In 18th Annual North American Waste-to-Energy Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/nawtec18-3502.

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The City of Marion (“City”) and wastenotIowa, Inc. (WNI), along with other interested parties, has been considering the use of a plasma are gasification plant (“Plant”) as a technology that could reduce their future dependency on landfill disposal. As currently envisioned, the Plant would serve Linn County, including the City and the University of Iowa (“UI”) Oakdale research campus, located in Johnson County. In the next step of their evaluations, the City along with the Iowa Department of Natural Resources (DNR) has commissioned SCS Engineers (SCS) to perform a formal economic feasibility study of the Plant. The feasibility study included: •Assessing potential for other waste material other than municipal solid waste in the region as supplemental plant feedstock. •Assessing potential markets for the plasma plant byproducts. •Determining the feasibility, requirements and costs related to an interconnect with the power utility grid. •Assessing the option that the UI could potentially be the exclusive power customer for the Plant. •Developing a pro-forma model so that various options can be evaluated for the Plant capacity and material and energy output configurations over an assumed initial 20-year contract operating phase, including; –Production of syngas for conversion to electrical power –Production of syngas for direct use and conversion to fuel products –Production of insulation from slag to enhance project revenues. •Determining the potential economic impact of the Plant on the region.
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Zhang, Zhi-gang, and Ken-ichiro Sugiyama. "Fragmentation of a Single Molten Stainless Steel and Aluminum Droplet Penetrating a Sodium Pool." In 18th International Conference on Nuclear Engineering. ASMEDC, 2010. http://dx.doi.org/10.1115/icone18-29523.

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In order to clarify the fragmentation of molten core structural material (stainless steel) and molten metallic fuel and claddings on liquid phase formed by metallurgical reactions (liquefaction temperature = 650°C) during core disruptive accidents (CDAs), the present study focuses on the fragmentation of single molten stainless steel (316SS) and aluminum droplet penetrating a sodium pool. The temperatures of 3–5g molten aluminum droplets were 1002 to 1399°C, and the sodium pool was about 300°C. The instantaneous contact interface temperatures (Ti) between the molten aluminum droplets and liquid sodium were calculated to be from 741°C below the boiling point of sodium (Tc,bp) to 1019°C above Tc,bp. The temperatures of 5g molten 316SS droplets were 1510 to 1706°C, and the temperatures of sodium pool vary about 300–400°C. The Ti values between the molten 316SS droplets and liquid sodium were calculated to be from 916 to 1082°C. Fragmentation of the single molten aluminum droplet was clearly observed even at Ti ≪ Tc,bp. When Ti is approximately equal to or higher than the boiling point, the intensive fragmentation of droplet was clearly observed independent of Wea condition. Fragmentation of the single molten 316SS droplet was clearly observed even at Ti below its melting point. The Dm values of aluminum and 316SS droplets with relatively high Wea tend to be lower than those of droplets with relatively low Wea under the relatively low Ti condition. These results indicate the fragmentation of the molten core structural material and eutectic alloy fuels in liquid phase formed by the metallurgical reactions could possibly occur under the low Ti condition below and above the sodium boiling point, which is promising to assure the termination of accidents in CDAs and useful to the core design with enhanced safety in FBRs.
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Willis, Catherine M., та Michael Klüppel. "Abstract 3250: Chondroitin sulfate-mediated regulation of Wnt/β-catenin signaling in breast cancer". У Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-3250.

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Ren, Dian, Bo Zhang, Renwang Liu, et al. "Abstract 380: WNT signal pathway activation correlates with innate resistant to immune checkpoint therapies in NSCLC." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-380.

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Kong, Deming, Haiyun Xin, Kwangwoong Kim, et al. "300 Gb/s Net-Rate Intra-Datacenter Interconnects with a Silicon Integrated Optical Frequency Comb Modulator." In Optical Fiber Communication Conference. OSA, 2020. http://dx.doi.org/10.1364/ofc.2020.w2a.1.

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Rajakulendran, Nishani, Hayden Selvadurai, Katherine Rowland, et al. "Abstract B14: Wnt signaling circuits in glioblastoma multiforme." In Abstracts: AACR Special Conference on Developmental Biology and Cancer; November 30 - December 3, 2015; Boston, Massachusetts. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1557-3125.devbiolca15-b14.

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Carbone, Carmine, Geny Piro, Raffaela Santoro, et al. "Abstract 3501: Adipocytes sustain pancreatic cancer progression through a non-canonical WNT paracrine network inducing ROR2 nuclear shuttling." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-3501.

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Koga, Hironori, Miran Kim, Anna Nakamura, et al. "Abstract 330: The Wnt signal transcription factor TCF-4 directly regulates Bcl-xL expression in human hepatocellular carcinoma cells." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-330.

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Jelínková, H., M. E. Doroshenko, V. V. Osiko та ін. "Fe:Zn0.6Mn0.4Se Spectroscopic Properties and Laser Generation at 5.0–5.8 μm in the Temperature Range of 78–300 K". У Conference on Lasers and Electro-Optics/Pacific Rim. OSA, 2018. http://dx.doi.org/10.1364/cleopr.2018.w3a.56.

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