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Dissertations / Theses on the topic 'Wogonin'

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1

Ding, Jie [Verfasser], and Peter [Akademischer Betreuer] Angel. "Mechanism of Wogonin-mediated sensitization of HTLV-1-associated ATL cells to TRAIL-induced apoptosis / Jie Ding ; Betreuer: Peter Angel." Heidelberg : Universitätsbibliothek Heidelberg, 2011. http://d-nb.info/117922924X/34.

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2

Zhang, Wogong [Verfasser], and Jörg [Akademischer Betreuer] Schulze. "Realization of silicon-based monolithic E-band IMPATT-transmitter and Schottky-receiver for wireless applications / Wogong Zhang ; Betreuer: Jörg Schulze." Stuttgart : Universitätsbibliothek der Universität Stuttgart, 2019. http://d-nb.info/1197613102/34.

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3

Chang, Chia-Chen, and 張嘉真. "Biopharmaceutical Studies of Wogonin in Rabbits." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/95824993493780673277.

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碩士<br>中國醫藥學院<br>中國藥學研究所<br>84<br>Wogonin, an active constituent isolated from the root of Scutellaria baicalensis Georgi (Woogon), a frequently use herb in China, possesses antiinflammatory, antispasmodic and lipid- lowering effect. In this study, the pharmacokinetics and bioavailability of wogonin in rabbits were evaluated.A simple high-performance liquid chromatographic method was self- developed for the determination of wogonin in plasma samples.The pharmacokinetics of wogonin in the rab
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4

Chiu, Wei-Ming, and 邱韋銘. "Syntheses of Wogonin、Oroxylin A and PD98059." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/kf8v5b.

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碩士<br>國立東華大學<br>化學系<br>96<br>Flavonoids such as wogonin and oroxylin A performed potent anti-free radical activity, anti-inflammation, anti-lipid peroxidation, and inhibition of tumor cell growth. Wogonin was isolated from Scutellaria baicalensis Georgi, and found can induce cell apoptosis. In addition, oroxylin A effectively induces the vasodilatation to prevent or alleviate the hypertention. One of the flavonoids, PD98059 selectively blocks the activity of MAP kinase kinase (MAPKK), therefore inhibits the activation of MAP kinase (MAPK) and cell growth. Furthermore, another study found
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Lay, Ing-Shiow, and 賴英秀. "Effect of Chrysin and Wogonin on the Gene Regulation of." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/18174817957510605371.

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6

Shyu, Chi-Chuo, and 徐綺灼. "Effects of Baicalein and Wogonin on Chemoprevention and Xenobiotic Interactions." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/96081349460276154452.

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碩士<br>國立陽明大學<br>藥理學研究所<br>88<br>Baicalein and wogonin, the main bioactive flavonoids present in Scutellaria baicalensis, have been commonly used in traditional Chinese medicine. Previous reports have demonstrated that oral treatment of rat with crude extract of Scutellaria baicalensis could affect cytochrome P450 (CYP) and intraperitoneal treatment of rats with baicalein and wogonin showed hepatoprotective effects against CCl4 and galactosamine. Therefore, effects of baicalein and wogonin on the gentoxicities of carcinogens and drug-metabolizing enzymes were studied. In vitro, baicalein and wo
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7

Lin, Chiu-Mei, and 林秋梅. "Inhibitory Effects of Wogonin and Chrysin on Inflammation-stimulated Angiogenesis." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/27072357721909907527.

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博士<br>國立陽明大學<br>傳統醫藥學研究所<br>94<br>Angiogenesis plays an important role in many human disorders, such as tumor formation and myocardial infarction. In angiogenesis, vascular endothelial growth factor (VEGF) plays a central role and present in response to inflammation, shear stress, and hypoxia. VEGF is involved in the endothelial cell proliferation, motility, and vascular permeability through the binding with the tyrosine kinase receptors (VEGFR-1 and VEGFR-2) expressed in endothelial cells. Several transcription factors, including STAT3, have been shown to up-regulate VEGF gene expression in d
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8

Lee, Yu-Lun, and 李育綸. "Study of the Interaction between Wogonin and Benzo[a]pyrene." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/20264652165833475263.

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碩士<br>國立陽明大學<br>口腔生物研究所<br>98<br>Oral cells can be exposed to polycyclic aromatic hydrocarbons (PAHs) through charcoal grilled food or cigarette smoke. PAHs are widely distributed environmental contaminants. The PAH, benzo[a]pyrene has been demonstrated to cause carcinogenic, mutagenic, cytotoxic, and teratogenic effects in various animal species and tissues.. Through the activation of aryl hydrocarbon receptors (AhR) and the following binding of AhR-ligand complex to dioxin response element, benzo[a]pyrene induce the transcription and translation of cytochrome P450 1A (CYP1A). CYP1A occupies
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9

Huang, Ho-Chun, and 黃鶴群. "INHIBITION OF WOGONIN, RUTIN AND QUERCETIN ON LIPOPOLYSACCHARIDE-INDUCED INFLAMMATORY RESPENOSES." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/27115975123946725934.

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碩士<br>台北醫學院<br>生藥學研究所<br>89<br>Flavonids are major components of natural products and several biological activities have been explored extensively including antioxidant , anti-inflammation and anti-cancer . Our present study indicated that wogonin , rutin and quercetin showed the significant inhibition on Lipopolysaccharide(LPS)-induced inducible nitric oxide synthase(iNOS) and Cyclooxygenase-2 (COX-2), Prostaglandin(PGE2)production in RAW 264.7 macrophages. As the same part of experiment, wogonin and quercetin inhibited LPS-induced iNOS gene expression and NO production in primary
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10

Lee, Hsin-Hsueh, and 李欣學. "Neuroprotective Effects of Wogonin, Baicalin and Baicalein in Primary Cultured Central Neurons." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/44069473884404217075.

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碩士<br>台北醫學院<br>生藥學研究所<br>89<br>Neuronal injury in the central nervous system following ischemic insult is now believed to result from excitotoxicity mediated by glutamate receptors, especially the N-methyl-D-aspartic acid (NMDA) receptor. Therefore, attenuation of NMDA receptor activity may provide a neuroprotective effect to ischemia-insulted brain. In this study, polyphenols, anthraquinones and flavonoids were investigated for their effects on neuronal survival. We used the primary cultured neurons isolated from embryonic rat brains. Cultures were subjected to glutamate and NMDA for 24 hour
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11

Chen, Chien-Yu, and 陳建宇. "Effect of Wogonin on Lipolysis in Adipocytes and Cholesterol Efflux in Macrophages." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/69753185687977923315.

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博士<br>國立陽明大學<br>生理學研究所<br>99<br>Lipid metabolism is essential for maintenance of physiological function and life. However, dysregulation of lipid metabolism, also called lipid abnormality, has been considered as a severe health problem in developing or developed countries. Hyperlipidemia, including higher level of serum triglyceride or cholesterol, is the most common lipid abnormality and associates with the obesity and atherosclerosis. Over the past decade, the ultimate goal of clinical trails for therapy of obesity or atherosclerosis has been shifted to explore the new classes of agents, whi
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12

Chang, Chao Lung, and 張櫂湰. "Wogonin inhibits basic fibroblast growth factor induced proliferation and migration of vascular smooth muscle cells." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/d88tz6.

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13

Tsai, Shan-Tin, and 蔡萱亭. "Mechanistic Studies of Anti-inflammatory Activity of Scutellariae radix and Wogonin in Human Hepatoma Cells." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/81006822908074847442.

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碩士<br>國立陽明大學<br>生化暨分子生物研究所<br>98<br>IL-1β and CC-chemokines are proinflammatory cytokines, play an essential role in many chronic inflammatory disease. CC-chemokines are regulated by IL-1β, which triggers the invasion of immune cells into a site of infection. In previous study from our laboratory, it has been found that Chinese herbal medicine Scutellariae radix and one of its constituent wogonin possess anti-HBV activity. In this study, IL-1β-induced CC-chemokines MIP-1β expression in Huh7 cells was selected as a cell model to study the anti-inflammatory activity of Scutellaria radix and one
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14

Wang, Cyong-Ling, and 王瓊玲. "Cellular and molecular mechanism underlying neuroprotective effects of wogonin against brain injury induced by ischemia/reperfusion." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/49146605934610470406.

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碩士<br>國防醫學院<br>生理學研究所<br>95<br>Focal cerebral ischemia-reperfusion (I/R) results in characteristic histopathological changes that manifest as a “necrotic core” in which cells die rapidly, and a surrounding “penumbra” region of variable size in which neurons die over an extended time period of days to weeks. In this thesis, I used a rat model of focal cerebral I/R by microinjection of endothelin-1 (400 pmol in 20 μl saline) to middle cerebral artery and unilateral ligation of common carotid artery. Cerebral ischemia, as evidenced by the decrease of the regional cerebral blood flow to 20~25% of
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15

Wu, Yi-Chieh, and 吳宜潔. "Mechanistic study of anti-human hepatitis B virus activity of Scutellaria radix & Wogonin in human hepatoma cells." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/63318464136137914502.

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碩士<br>國立陽明大學<br>生化暨分子生物研究所<br>97<br>Hepatitis B virus (HBV) infection causes acute and chronic hepatitis, and the affected patients have an increased risk of developing liver cirrhosis and hepatocellular carcinoma (HCC). Although a preventive vaccine for HBV is available, effective drugs to eradicate HBV in chronic carriers are still urgently needed.The Chinese herbal medicine Xiao-Chai-Hu-Tang consists of Bupleuri radix and Scutellaria radix (HD-1S) and is widely used for treatment of liver disease. In searching of compounds on suppression of hepatitis B surface antigen (HBsAg) production, ou
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16

Wang, HsiangChing, та 王湘晴. "合成與活性評估新型wogonin衍生物作為抗癌藥劑". Thesis, 2010. http://ndltd.ncl.edu.tw/handle/86844952036466373323.

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17

Chou, Hsiao Fang, та 周孝芳. "Wogonin modulates cytokine-induced serum amyloids A protein expression in HepG2 cell lines-roles of STAT3, NF-κB and C/EBPβ". Thesis, 2015. http://ndltd.ncl.edu.tw/handle/cquc3s.

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18

Wang, Hui-Hung, and 王慧虹. "Study of pharmacological actions of the water extract of huangqin and its principles baicalin、wogonin and chrysin on central GAGAergic system." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/29055115682836264887.

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19

Chen, Chien Cheng, and 陳建成. "Investigating Neuroprotective Effects and Mechanism of Wogonin – A Preclinical Study Using Traumatic Brain Injury Animal Model with Integrative, Multi-Mechanism Approach." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/54945093790087124289.

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博士<br>國立臺灣大學<br>醫學工程學研究所<br>101<br>Background: Treating and managing neurological sequelae of traumatic brain injury (TBI) patients are difficult and keep challenging medical stuff despite of the advancement of technology. Many drugs that proved efficacy in experimental models failed to show the benefits in the treatment of TBI population, so as many reviews did not support that those efficacy treatment in animal models effected. There is strong need of well-designed and controlled animal models with an integrative, multi-mechanism approach for drug discovery and study in order to establish de
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20

Su, Ming-Yuan, and 蘇明源. "The Ihibitory Effect on Lipopolysaccharide-Induced Nitric Oxide Formation in RAW 264.7 Cells by the Principles of Scutellaria baicalensis Georgi, Baicalein, Wogonin and Chrysin." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/93518214683924405238.

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