Journal articles on the topic 'World Year of Slovaks, 1997-1998'

Global activity continued to gain momentum in the early months of this year, helped by above trend growth in the North American economies. There was also a temporary acceleration in the growth of consumers' expenditure in Japan prior to a rise in indirect taxes in April. Total output in the OECD economies is estimated to have risen by 0.9 per cent in the first quarter of the year to a level 2.9 per cent higher than a year earlier. Output in the NAFTA member states rose by 1.4 per cent, and was over 4 per cent higher than in the first quarter of 1996. Conditions appear to remain favourable for steady growth through the remainder of this year, with OECD GDP projected to rise by 2¾ per cent in 1997 and 2½ per cent in 1998.

It is increasingly clear that the world economy has been recovering relatively strongly from a pause in activity at the end of 1995. The recovery has also been relatively well spread around the globe, with Japan displaying the strongest growth amongst the larger economies, in part because of the effects of the depreciation of the yen, but also because government policy was expansionary throughout last year. Although growth rates in Europe appear low in 1996, with Germany and France both recording growth of less than 1½ per cent, growth through the year has generally been strong. It appears there is still some spare capacity in Europe, and hence growth can be expected to strengthen further into 1998, at least within continental Europe. The US economy has been growing at or above capacity for several years; in the fourth quarter of last year output rose by a further 1 per cent, with growth through the year of over 3 per cent. Domestic demand also rose strongly in Canada and Mexico in the latter half of last year. Growth in the NAFTA economies is expected to strengthen in 1997, but to slow into 1998 in the aftermath of moves to tighten monetary policy. Overall, as can be seen from Table 1, we expect a period of above trend growth and low inflation in the majority of the OECD countries.

The European Advisory Group on Immunisation has recommended that measles should be eliminated from Europe by the year 2007 , a target accepted by National Immunisation Programme Managers for the World Health Organization (WHO) European Region countries. I

Coping with the prevention, diagnosis and therapy of cancers is a challenging medical task with continuing consequences for the development of population health status and economy of health in each country. The occurrence of cancers shows an upward trend in the world. A comprehensive fight against cancers should involve the spatial aspect which is best applied in the field of medical geography. The key indicators for the surveillance of cancers include mortality and incidence, but also prevalence. Incidence plays a more and more important role in the period of an increase in cancers. In the investigation of this issue specific analytical methods were used, such as spatial autocorrelation. Standardized cancer incidence in Slovakia was analyzed in the case of men and women. The years 1997, 2009 and the period 1997–2009 were chosen to compare the incidence. The results of partial analyses show the situation in districts of Slovakia from the perspective of incidence development and its spatial differentiation.

A 1998 survey was conducted in the Willamette Valley of Oregon, the major U.S. production area for orchardgrass seed, to determine the extent and severity of choke disease in Dactylis glomerata. This disease is a severe constraint to orchardgrass seed production in other parts of the world, but was unknown in Oregon prior to 1997. Thirty-seven fields, representing 27 cultivars and the geographical extent of production in the Willamette Valley, were selected from a list of fields registered for certification. Choke was found in 26 (70%) of the fields, and disease incidence ranged from <0.05 to 28% tillers affected. Five of the 37 fields had only trace levels of the disease, but four of the fields, representing three counties, had incidences >10%. In a survey of 16 fields located within 3.5 km of the 1997 discovery, choke was found in 14 fields, of which three had incidences >20%. Increase in disease incidence between 1997 and 1998 ranged from 2.1- to 3.3-fold in the three fields where disease increase was measured. One year after its presence was confirmed in Oregon, choke disease of orchardgrass is well-established throughout the orchardgrass seed producing region at damaging levels and is apparently able to increase and spread under the prevailing climatic and cultural conditions.

In autumn 1996, under the Presidency of Dr Robert Kendell, the College decided to mount a campaign to tackle the stigmatisation of people with mental illnesses. In 1997, a working party proposed goals, content, process and a 5-year governance. Other campaigns, both here and abroad, have either generically addressed ‘mental health problems' (e.g. Mind's ‘Respect’ Campaign) or targeted a specific mental illness, e.g. the World Psychiatric Association's anti-stigma campaign in respect of people with schizophrenia. Our working party decided that it might be timely to recognise the differences in public attitudes to the variety of mental illnesses. The campaign thus addressed six categories of mental illness: anxiety disorders, depressive disorders, schizophrenia, the dementias, eating disorders, and drug and alcohol misuse/addiction. Target populations were identified as doctors, children and adolescents, the workplace, the media and the general public. The working party had also secured funding and arranged for a survey, in July 1998, by the Office for National Statistics of opinions of the British public concerning people with these mental illnesses (Crisp et al, 2000). The Campaign started on 7 October 1998. Since that time, and drawing upon our survey findings within its initial literature review (Kelly, 1999) the Department of Health mounted its own anti-stigma campaign, ‘Mind Out for Mental Health’, which addressed a similar range of mental illnesses.

What is a place of work? Is it a commitment to work, or continuous pressure under work, or hunting for income? This article is a brief review about the main milestones of the employment history of the European Union and Hungary. In 1989, the Social Charta about the social principles of employee was issued. In 1997 the employment policy became the part of the acquis communautaire. Finally, in 1998, the EuropeanEmployment Strategy was developed, which contains the community employment guidelines. In the year of millennium, the new long term concept of the EU, the Lisbon Strategy was approved. In this document the EU was targeted as the most dynamic and competitive knowledge-based economy in the World till 2010. The Tens joint to the EU in 2004, and a bit later it became clear, that the EU is light-armed against some of the world economy challenges. As a consequence, many objectives of the Strategy could not be reached. Recently member states of the EU have to develop the national action plan for employment year by year. The hungarian plans were developed as well, but the wrong labour market’s parameters haven’t been changed since 2004.

The world economy appears to have embarked upon a cyclical upturn this year. Despite the widespread fears of a year ago, the downturn in global demand that began in the latter half of 1997 proved unusually mild and short-lived compared to others seen in the past three decades. Our latest projections indicate that global output growth is likely to have picked up to 2.9 per cent this year from 2.4 per cent in 1998, and may accelerate further to 3¼ per cent next year. In the OECD economies output growth has accelerated this year to 2.8 per cent, with a continued robust expansion in North America and a gradual stabilisation of the Japanese economy more than offsetting the relatively mild slowdown in the Euro Area and the UK. Elsewhere there has been a strong rebound in output in many of the Asian economies, and the impact of the currency crises in Brazil and Russia appears to have been absorbed more easily than had been expected at the time they occurred.

The global climate during 1998 was affected by opposite extremes of the ENSO cycle, with one of the strongest Pacific warm episodes (El Niño) in the historical record continuing during January–early May and Pacific cold episode (La Niña) conditions occurring from JulyñDecember. In both periods, regional temperature, rainfall, and atmospheric circulation patterns across the Pacific Ocean and the Americas were generally consistent with those observed during past warm and cold episodes. Some of the most dramatic impacts from both episodes were observed in the Tropics, where anomalous convection was evident across the entire tropical Pacific and in most major monsoon regions of the world. Over the Americas, many of the El Niño– (La Niña–) related rainfall anomalies in the subtropical and extratropical latitudes were linked to an extension (retraction) of the jet streams and their attendant circulation features typically located over the subtropical latitudes of both the North Pacific and South Pacific. The regions most affected by excessive El Niño–related rainfall included 1) the eastern half of the tropical Pacific, including western Ecuador and northwestern Peru, which experienced significant flooding and mudslides; 2) southeastern South America, where substantial flooding was also observed; and 3) California and much of the central and southern United States during January–March, and the central United States during April–June. El Niño–related rainfall deficits during 1998 included 1) Indonesia and portions of northern Australia; 2) the Amazon Basin, in association with a substantially weaker-than-normal South American monsoon circulation; 3) Mexico, which experienced extreme drought throughout the El Niño episode; and 4) the Gulf Coast states of the United States, which experienced extreme drought during April–June 1998. The El Niño also contributed to extreme warmth across North America during January–May. The primary La Niña–related precipitation anomalies included 1) increased rainfall across Indonesia, and a nearly complete disappearance of rainfall across the east-central equatorial Pacific; 2) above-normal rains across northwestern, eastern, and northern Australia; 3) increased monsoon rains across central America and Mexico during October–December; and 4) dryness across equatorial eastern Africa. The active 1998 North Atlantic hurricane season featured 14 named storms (9 of which became hurricanes) and the strongest October hurricane (Mitch) in the historical record. In Honduras and Nicaragua extreme flooding and mudslides associated with Hurricane Mitch claimed more than 11 000 lives. During the peak of activity in August–September, the vertical wind shear across the western Atlantic, along with both the structure and location of the African easterly jet, were typical of other active seasons. Other regional aspects of the short-term climate included 1) record rainfall and massive flooding in the Yangtze River Basin of central China during June–July; 2) a drier and shorter-than-normal 1997/98 rainy season in southern Africa; 3) above-normal rains across the northern section of the African Sahel during June–September 1998; and 4) a continuation of record warmth across Canada during June–November. Global annual mean surface temperatures during 1998 for land and marine areas were 0.56°C above the 1961–90 base period means. This record warmth surpasses the previous highest anomaly of +0.43°C set in 1997. Record warmth was also observed in the global Tropics and Northern Hemisphere extratropics during the year, and is partly linked to the strong El Nino conditions during January–early May.

The world-systems perspective was invented for modeling and interpreting the expansion and deepening of the capitalist regional system as it emerged in Europe and incorporated the whole globe over the past 500 years (Wallerstein 1974; Chase-Dunn 1998; Arrighi 1994). The idea of a core/periphery hierarchy composed of “advanced” economically developed and powerful states dominating and exploiting “less developed” peripheral regions has been a central concept in the world-systems perspective. In the last decade the world-systems approach has been extended to the analysis of earlier and smaller intersocietal systems. Andre Gunder Frank and Barry Gills (1994) have argued that the contemporary global political economy is simply a continuation of a 5,000-year-old world system that emerged with the first states in Mesopotamia. Christopher Chase-Dunn and Thomas Hall (1997) have modified the basic world-systems concepts to make them useful for a comparative study of very different kinds of systems. They include very small intergroup networks composed of sedentary foragers, as well as larger systems containing chiefdoms, early states, agrarian empires, and the contemporary global system in their scope of comparison.

AbstractWe examine the impact of the 1997 Asian Crisis on governance. We look into how the crisis affected High-Income OECD, High-Income Non-OECD, Upper-middle Income, Lower- Middle Income, and Low Income Countries. For measures of governance, we use the World Bank’s Governance Indicators dataset which includes six measures of governance. We find that pre- and post-crisis, the ranking of each income group has not changed except for year 2004 when the High-Income Non-OECD Countries surpassed the High-Income OECD Countries in “Political Stability and Absence of Violence” category. In other words, our results show that, other than that exception in 2004, both pre- and post-crisis, the High-Income OECD Countries had the best governance measures, the High-Income Non-OECD Countries had the second best measures, and so on, in the order shown above. One point to note here: The High-Income Non- OECD Countries performed much better than the other groups after year 1998. After 1998, this group improved in all six dimensions of governance. We conclude that although crises affect all income groups, because of certain characteristics of the High-Income Non-OECD group, they tend to better react to crises.

Abstract. Over the past decades, fires have burned annually in Indonesia, yet the strength of the fire season is for a large part modulated by the El Niño Southern Oscillation (ENSO). The two most recent very strong El Niño years were 2015 and 1997. Both years involved high incidences of fire in Indonesia. At present, there is no consistent satellite data stream spanning the full 19-year record, thereby complicating a comparison between these two fire seasons. We have investigated how various fire and precipitation datasets can be merged to better compare the fire dynamics in 1997 and 2015 as well as in intermediary years. We combined nighttime active fire detections from the Along Track Scanning Radiometer (ATSR) World Fire Atlas (WFA) available from 1997 until 2012 and the nighttime subset of the Moderate-Resolution Imaging Spectroradiometer (MODIS) sensor from 2001 until now. For the overlapping period, MODIS detected about 4 times more fires than ATSR, but this ratio varied spatially. Although the reasons behind this spatial variability remain unclear, the coefficient of determination for the overlapping period was high (R2 = 0. 97, based on monthly data) and allowed for a consistent time series. We then constructed a rainfall time series based on the Global Precipitation Climatology Project (GPCP, 1997–2015) and the Tropical Rainfall Measurement Mission Project (TRMM, 1998–2015). Relations between antecedent rainfall and fire activity were not uniform in Indonesia. In southern Sumatra and Kalimantan, we found that 120 days of rainfall accumulation had the highest coefficient of determination with annual fire intensity. In northern Sumatra, this period was only 30 days. Thresholds of 200 and 305 mm average rainfall accumulation before each active fire were identified to generate a high-incidence fire year in southern Sumatra and southern Kalimantan, respectively. The number of active fires detected in 1997 was 2.2 times higher than in 2015. Assuming the ratio between nighttime and total active fires did not change, the 1997 season was thus about twice as severe as the one in 2015. Although large, the difference is smaller than found in fire emission estimates from the Global Fire Emissions Database (GFED). Besides different rainfall amounts and patterns, the two-fold difference between 1997 and 2015 may be attributed to a weaker El Niño and neutral Indian Ocean Dipole (IOD) conditions in the later year. The fraction of fires burning in peatlands was higher in 2015 compared to 1997 (61 and 45 %, respectively). Finally, we found that the non-linearity between rainfall and fire in Indonesia stems from longer periods without rain in extremely dry years.

This case, and the accompanying teaching note, is based on extensive interviews in the early months of the year 2000 with many of the participants involved in Global 2000—an organization set up to preempt a possible global business meltdown as a result of the “Millenium Bug.” Global 2000 emerged between November 1997 and April 1998 as a coordinated project among managers at various international banks to monitor suspicious private and public organizations from around the world, engage national and multilateral regulators, and develop and implement a workable strategy to forestall the worst potential consequences of the Year 2000 (Y2K) bug. This project involved maintaining control over a rapidly expanding network, establishing readily implementable procedures, setting incentives for a diverse community of players, and agreeing on effective country assessment charts. If they succeeded, they ran the risk of being criticized for crying wolf; if they failed, the world financial system would be at stake. This article tells the story of Global 2000's efforts to squash the Y2K bug and discusses the lessons of this story for our understanding of issues of collective action, network dynamics, and voluntary compliance.

This article not only offers a chronological overview of the development of occupational medicine, but also offers a summary of occupational diseases recommended by the ILO and legislative decisions that have influenced how we approach assessment today. We consider that these areas form a whole in which they cannot function without each other and they would lose their relevance if the system was collapsed. By excluding even one part of it, we would find ourselves at the beginning of the era of occupational medicine, and a large number of employees would once again be exposed to conditions that previously led to considerable illness and mortality of employees. The article also examines legislation and the development of occupational diseases in Slovakia in the period 1997–2019. Using basic statistical methods and time series, a trend model for the time series of the development of the number of occupational diseases over the last 20 years is created. The modeling also includes a forecast for the development of the number of occupational diseases for the next 5 years. The model created shows a favorable, decreasing trend in the number of occupational diseases in Slovakia.

The purpose of the study was to assess the competitive position of the dairy sector in international trade in 1998-2017. The analysis of the concentration of global milk production in the years covered by the study was also presented in the paper. The data from the FAO and the information provided by the CLAL constituted the reference source for the conducted research. The study presents the assessment of: trends in production, export and import changes, trends in percentage share changes of major milk producers, exporters and importers and also the competitive position of dairy product exporters. The analysis covered 20 largest global producers and exporters of these products. In the analysed period, the largest milk producers were as follows: India, the United States, Russia, Germany, France and Pakistan. China significantly increased its production share in recent years, whereas Russia, Germany and France reduced their share in global milk production. The following EU countries are listed among the leading exporters of dairy products: Germany, Belgium, the Netherlands, France and the Czech Republic. The highest export growth dynamics were recorded in: Poland, the Czech Republic, Latvia, Estonia and Slovakia. The analysed period was characterised by a strong concentration of countries producing and exporting dairy products and an increase in pro-export orientation among the largest exporters of these products in global markets. After joining the European Union, Poland’s competitive position on the discussed market was gradually improving.

Editorial The year 2010 is not gone yet but we already know that this year will be associated with one of the biggest losses in pharmacology and toxicology. On Tuesday, April 13, 2010, at the age of 97, one of the most influential pharmacologists in Eastern Europe, Professor Helena Rašková has left us. Her wisdom, generosity, kindness and hard work made it possible to create a positive environment for research and education, although sometimes she had to fight hard. Her incredible story "How I became a Pharmacologist" wroted by Prof. Rašková herself documents how rich and inspirational her life was [Rašková H. (1997). Pharmacology & Toxicology 80: 255-261]. In this issue you will find mostly works of her colleagues and friends who would like to pay homage to the mother and grandmother of Czecho-Slovak pharmacology and toxicology and to the wonderful person who Prof. Helena Rašková was. She touched many people in her lifetime, affected many and will truly be missed.

The eastern Pacific jumbo squid (Dosidicus gigas) is one of the largest and most abundant squid of the world ocean. To reveal possible interannual variability in the life span, statoliths were used to determine the age of mature females belonging to two modal size groups (<490 and >500 mm mantle length) collected before (1991–1996), during (1997–1998), and after (1999–2011) a strong El Niño event in Peruvian waters. We found that water temperatures encountered between the third and sixth months of ontogenesis had the strongest negative effect on age. Together with a weaker but significant negative effect of temperatures encountered during early life (first to third months) and later ontogenesis (seventh and eighth months), these temperature parameters (along with other environmental factors) were important in determining whether a given animal had a 1-year life cycle (early maturation and small size) or a 1.5- to 2-year life cycle (delayed maturation and large size). The possible cause of a sudden increase in abundance of large D. gigas in 2000–2001 is discussed.

Echovirus type 30 (E30) (genus, Enterovirus; family,Picornaviridae) has caused large outbreaks of aseptic meningitis in many regions of the world in the last 40 years. U.S. enterovirus surveillance data for the period 1961 to 1998 indicated that the annual proportion of E30 isolations relative to total enterovirus isolations has fluctuated widely, from a low of 0% in 1966 to a high of 42% in 1998. Peaks of E30 isolations occurred in the years 1968 to 1969, 1981 to 1984, 1990 to 1993, and 1997 to 1998, coincident with large nationwide outbreaks of E30-associated aseptic meningitis. Analysis of the complete VP1 sequence (876 nucleotides) of 136 E30 strains isolated in geographically dispersed regions of the United States and nine other countries between 1956 and 1998 indicated that the currently circulating E30 strains are genetically distinct from those isolated 30 to 40 years ago. Phylogenetic reconstruction demonstrated the existence of at least four distinct genetic groups, three of which have not been isolated in North America since 1981. Two of the three groups disappeared during periods when E30 was isolated infrequently. All North American E30 strains isolated after 1988 were closely related to one another, and all post-1993 isolates were of the same lineage within this group. Surveillance data indicate that E30 causes large national outbreaks of 2- to 4-year durations, separated by periods of relative quiescence. Our results show that shifts in the overall genetic diversity of E30 and the predominant genetic type correlate temporally with the dynamics of E30 isolation. The sequence data also provide a basis for the application of molecular techniques for future epidemiologic investigations of E30 disease.

To understand the effects of tourism and climate change on wetlands, a study was performed at Jiuzhaigou, a destination receiving >5 million people per year. There are 21 types of wetlands in region, covering an area of 265.1ha, with 42.8% on tufa. Wetland areas declined by 16.1% from 1983 to 1999 (autumn) and by 31.2% from 1983 to 2002 (summer) and increased by 31.8% from 1999 to 2011 (autumn) and by 60% from 2002 to 2014 (summer). Wetland changes included dissolving tufa, a reduced tufa deposit rate, collapse of tufa mats, increases in water nutrients and algae, and marshland development. Mean annual air temperature increased from 1977. Annual precipitation varied from 430 to 810mm between 1951 and 2015, exhibiting an increasing trend from 2005 onwards. The number of both heavy rain and storm events increased from 2005. The number of tourists grew slowly from 1984 to 1997, but increased quickly from 360000 in 1998 to 5.1 million in 2015. Commercial logging between 1966 and 1978 and debris flows are probably the key factors contributing to increased lake sedimentation and marshland development. Rapid tourism development with intensive bus movement and regional air pollution likely caused changes in water chemistry, which, in turn, caused tufa changes and wetland degradation. Reducing tourist numbers is likely to be effective in reducing effects on wetlands and conserving them, but research is needed to determine appropriate tourist numbers.

The present social and economic conditions in Slovakia participate to the behaviour differentiation of individual households on the consumer market. It is possible to speak about changes both in the po­si­ti­ve and negative sense of word. The positive impact can be observed in the inter-annual increase of the population revenues especially in the years 2006 and 2007 (by 13.86 % and 12.05 %) in connection with greater possibilities of the employment growth and employment on the work market of the EU member countries. The negative manifestations can be seen within the low income household groups because they represent a great part of households in Slovakia. In spite of the fact that the final consumptions and expenditures of private households increased from 56.3 % in 2000 to 58.3 % in 2005 and it was manifested in GDP, and the growth of the population standard purchasing power increased from € 5400.00 to € 7700.00 per inhabitant (Eurostat 08), Slovakia is within the EU-27 countries at the lower bound of the achieved purchasing power standard (the Eurozone average is € 14000.00). Over the decennial period (1998–2007) the average annual monetary revenue increase of private households was 7.62 % and in 2007 it represented a nominal value of € 4158.269 and in the real expression it was € 4105.009 per a household member. In the past years the economic development in Slovakia (GDP growth by 10.4 % and the final household consumption by 7.1 % in 2007) enabled, at the average annual income growth by 7.62 %, an increase of consumption expenditures by 6.59 % for foodstuffs and for non alcoholic beverages by 3.66 %. This development is confirmed by income-demand analysis results.

Australia is perceived by many as the 'lucky' country and the image that has been portrayed to the rest of the world is one that projects a nation of tanned, active, healthy, and sports-loving individuals. This image is outdated and instead Australia is a nation with a national health problem. The health problem is having an impact which is increasingly problematic for governments. It has long been recognised that primary prevention, can be developed in two ways: by using a whole of population approach or through selective targeting (Naidoo & Wills, 1998). Within this context, this paper has chosen to explore and discuss a selective targeting approach through a case analysis of cardiovascular disease in regional Australia. In Australia, cardiovascular disease continues to be one of the major causes of death. This fact is a matter of great concern to all Australians but is particularly significant for people living in the regional city of Rockhampton, Central Queensland, where the death rate from cardiovascular disease is significantly higher than it is for the rest of the state of Queensland (354.4 deaths per 100,000 people per year compared with 310.6, Harper & Taylor, 1997, p. 21). The high death rate from heart disease in Queensland is even higher than the Australian average (Harper & Taylor, 1997, p. 22). Research previously conducted has revealed certain trends regarding cardiovascular disease. This research extends the available knowledge by measuring the cost in economic terms to the community. The findings explain the implications for Rockhampton employers and places regional health professionals in a better position to develop further research as well as to implement and explain alternative health strategies.

In 1998, the European Union (EU) entered into negotiations with Cyprus, the Czech Republic, Estonia, Hungary, Poland and Slovenia concerning the enlargement of the Union. At the end of 1999, the European Commission decided that six other countries could join the negotiations in 2000 (Bulgaria, Lithuania, Latvia, Slovakia, Malta and Romania), and it was suggested that a decision concerning the date of membership would be taken in 2002 for these applicants fulfilling all the criteria. Many questions still remain on both sides, in particular regarding institutional reform of the EU (Festoc, 1998), and the ability of the Central and Eastern European countries to adopt the “acquis”. In this article, we shall evaluate the ways in which the Central European countries (Poland, Hungary and the Czech Republic — the CECs) have already integrated to the Western European economy, using trade data over the last ten years. First, we show that since the beginning of the transition, a feature of the foreign trade of the CECs has been a strong reorientation from East to West, in particular to Germany, together with a rapid growth in trade between the EU and the CECs. Second, we describe the trade structure, focussed on foreign direct investment as a mean of developing new exports. The third and fourth sections study the development of the specialisations of the CECs and the nature of trade between the CECs and the EU respectively.

Current number of entrepreneurs in Indonesia is only 0, 18% or about 400.000 people. The number of entrepreneur in USA was 11, 5 % last year and the number of entrepreneur Singapore that had 4,24 million of population in 2005 was 7,2 %. The objectives of this research are to examine the effects entrepreneurship on business competence and performance of Padang Restaurants in special province of Yogyakarta. This study is expected to increase the number of entrepreneurship and is the solution of the unemployment problem in Indonesia is specially in Yogyakarta. 61 respondents from 72 Padang Restaurants. The data were collected using questionnaires and analyzed using Partial Least Square (PLS) analysis. Result of this study proved Ranidar finding (2004) which mentioned that the existence of Padang Restaurants is supported by the power of the norms which is from social and culture of Minang based on Islamic teaching (custom is based on Islam, Islam is based on Holy Quran). This finding also supports the theory of Minang culture. This theory is the concept of life which was prepared Minang’s anchestor for their generation who has purpose to reach a happy and prosperous life in this world and here after. (Idrus, 1998). The business competence has a big role in creating the business perfomance. (Hill and Jones, 1998, Muljadi, 1999). (Kotler 1997). Enterpreneurship depends on the ability of individual to run the business. Meredith et. al., (2000) stated that a person is called enterpreneur if he has an ability to see and find the opportunity and he believes in his own ability to plan, take a risk, inovate, and do some actions to get the goal. The finding of this study is important empirical evidence on the development of the theory and the practice of the enterpreneurship in Indonesia

Current number of entrepreneurs in Indonesia is only 0, 18% or about 400.000 people. The number of entrepreneur in USA was 11, 5 % last year and the number of entrepreneur Singapore that had 4,24 million of population in 2005 was 7,2 %. The objectives of this research are to examine the effects entrepreneurship on business competence and performance of Padang Restaurants in special province of Yogyakarta. This study is expected to increase the number of entrepreneurship and is the solution of the unemployment problem in Indonesia is specially in Yogyakarta. 61 respondents from 72 Padang Restaurants. The data were collected using questionnaires and analyzed using Partial Least Square (PLS) analysis. Result of this study proved Ranidar finding (2004) which mentioned that the existence of Padang Restaurants is supported by the power of the norms which is from social and culture of Minang based on Islamic teaching (custom is based on Islam, Islam is based on Holy Quran). This finding also supports the theory of Minang culture. This theory is the concept of life which was prepared Minang’s anchestor for their generation who has purpose to reach a happy and prosperous life in this world and here after. (Idrus, 1998). The business competence has a big role in creating the business perfomance. (Hill and Jones, 1998, Muljadi, 1999). (Kotler 1997). Enterpreneurship depends on the ability of individual to run the business. Meredith et. al., (2000) stated that a person is called enterpreneur if he has an ability to see and find the opportunity and he believes in his own ability to plan, take a risk, inovate, and do some actions to get the goal. The finding of this study is important empirical evidence on the development of the theory and the practice of the enterpreneurship in Indonesia

The Food and Agriculture Organization of the United Nations (UN FAO) has the most advanced information on water resources in all countries of the world, since the share of the agriculture sector in world water use is 70%. It operates the FAO Global Information System on Water and Agriculture (abbreviated as FAO Aquastat). The data contained in this database comes from the relevant government bodies of the countries of the world (reports, publications, official websites), from information bases of other UN agencies or international organizations (UN WHO – World Health Organization; UN FPA – United Nations Population Fund; ICOLD – International Commission on Large Dams) or obtained by modeling. The Water Resources section of the FAO global information system contains about 40 indicators. The database is filled with the average values of indicators for the segments of years: 1988-1992; 1993-1997; 1998-2002; 2003-2007; 20008-2012; 2013-2017. The assessment of water resources carried out in the article based on the database of the global information system FAO Aquastat (1988-2017). showed the following results in Ukraine: internal river flow – 50.1 km3; inflow from adjacent territories – 120.2 km3; total river runoff – 170.3 km3; available groundwater reserves – 5 km3; internal renewable water resources – 55.1 km3; total renewable water resources – 175.3 km3. In terms of total renewable water resources per person (3964 m3/person/year) among 50 European countries as of 2017, Ukraine ranked 27th. In terms of internal renewable water resources per person (1246 m3/person/year), Ukraine ranked 37th in Europe. In terms of total renewable water resources (175.3 km3), Ukraine ranked 6th in Europe. In terms of the volume of internal renewable water resources (55.1 km3), Ukraine ranked 14th. Ukraine has a high coefficient of external dependence of water resources (Кз = 66.8%), which characterizes the share of total renewable water resources formed outside the country in adjacent territories – 9th place in Europe. The data on the components of water resources in Ukraine, which are given in FAO Aquastat, differ from the data published in Ukrainian sources. It is necessary to pay special attention to this methodological problem in the scientific and expert environment, as well as among officials in our country – the State Agency for Water Resources of Ukraine, the Ministry of Environmental Protection and Natural Resources of Ukraine. Indeed, with the course towards European integration, there can be no difference in information for internal and external use.

AbstractIn Switzerland approximately 730 ha of tobacco are grown, mainly on small family farms. The main growing area is located in the French speaking part of the country, on altitudes ranging from 400 to 800 m above sea level. Approximately 93 % of the surface is planted with Burley and 7 % with Virginia. The cigarette manufacturers have to buy the whole crop of acceptable quality by law proportionally to their market share in Switzerland, in total approximately 1300-1500 tons per year. The buying organization, named SOTA (Societe cooperative pour l'achat du tabac indigene) has been created by the industry in 1930. It is responsible to buy and distribute the whole crop and finances a small research center with the aim to improve the quality. There is an agreement between the SOTA and the grower's organization FAPTA (Federation suisse des associations de planteurs de tabac) that limits the maximum surface to 730 ha. The price paid to the farmer is fixed by the government and is significantly higher than the world market price. The difference between the price paid to the farmer and the one paid by the industry is compensated by a specific fund which is under supervision of the custom and excise department. Because of several good crops, this system of subsidy became problematic. Therefore a new system of quota has been introduced for the 1997/1998 crop which limits the quantity of tobacco which can be delivered by each farmer.

Abstract Introduction Rituximab was approved in December 1997 and has since become the standard of care in diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and chronic lymphocytic leukemia (CLL). Clinical trials have shown statistically significant improvements in progression-free and overall survival. The objective of this study was to estimate the real-world effectiveness of first-line rituximab plus chemotherapy (R+Chemo) relative to chemotherapy alone (Chemo Alone) in the United States (US) from 1998 to 2013. Methods For each cancer, we constructed a population effectiveness model from 1998-2013 comprised of 3 modules: epidemiology, utilization and survival. The epidemiology module included age group, gender, and year-specific incidence rates for each cancer from the Surveillance, Epidemiology, and End Results (SEER) program from 2000-2010. Published SEER-based join-point estimates were used to extrapolate to other years. Census population data using the same age group, gender, and year strata were combined with incidence rates to project total diagnosed patient counts. The utilization module was based on SEER-Medicare linked data from 1999-2009. Drug utilization (defined as first infusion within 180 days of diagnosis for each cancer) for R+Chemo and for Chemo Alone was estimated as a proportion of all diagnosed patients, and stratified by age group, gender, and calendar year of diagnosis in the SEER-Medicare data. Utilization proportions were then multiplied by the diagnosed population counts to estimate treated patient counts for each cancer, by age group, gender, and calendar year. The survival module was calculated using SEER-Medicare data, starting from 30-days after first infusion, with follow up through 12/31/2010. For each cancer, flexible parametric (Royston-Parmar) survival models were applied to estimate restricted (10-year) mean survival times for each person, adjusted for individual patient covariates. These estimates were averaged across patients within strata defined by age group, gender and treatment. Life years lived were estimated for patients receiving R+Chemo, first by using mean survival for treatment with R+Chemo, and then by using mean survival estimates for Chemo Alone. The incremental life years saved were calculated as the difference between the projected survival from using R+Chemo and from using Chemo Alone. These differences were summed over age group, gender, and calendar year for each cancer. Monte Carlo sampling was used to estimate the 95% uncertainty intervals (UI). Results Across all three cancers, there were 289,793 cumulative life years saved (95% UI, 248,300-330,618; see Figure) from 1998 to 2013. For DLBCL, an estimated 177,952 patients were treated with R+Chemo. In these patients, an estimated 199,323 (95% UI 169,534-231,214) additional life years were lived compared to what might have occurred if Chemo Alone had been used instead. For FL, an estimated 84,303 patients were treated with R+Chemo, and an additional 80,338 (95% UI 53,876-106,709) life years were lived compared to Chemo Alone. For CLL, an estimated 14,398 patients were treated with R+Chemo, and an additional 10,132 (95% UI 4,469-15,998) life years were lived compared to Chemo Alone. Conclusions For DLBCL, FL and CLL patients treated with first-line therapy within 180 days of diagnosis in the US, approximately 290,000 cumulative life years were saved by adding rituximab to chemotherapy between 1998 and 2013. Next generation therapies may be able to extend these survival gains for patients with CLL, FL and DLBCL. Disclosures: Danese: Amgen: Consultancy, Research Funding; Genentech: Consultancy, Research Funding; Medimmune: Consultancy, Research Funding. Gleeson:Amgen, Inc.: Consultancy, Research Funding; Genentech: Consultancy, Research Funding; MedImmune: Consultancy, Research Funding. Halperin:Genentech: Consultancy, Research Funding; Medimmune: Consultancy, Research Funding; Amgen: Consultancy, Research Funding. Skettino:Genentech: Employment, stock Other. Reyes:Genentech, inc: Employment, Equity Ownership.

Immediately after World War II, economic and human losses due to water disasters were enormous in Japan. In the years of 1947 and 1953, for example, economic loss reach 10% of personal income, and the number of lives lost in the 1959 Isewan Typhoon exceeded 5,000. The Japanese government then implemented successive 5-year flood control plans that dramatically reduced such disasters. Economic loss by flooding now is on the order of 0.2% of personal income, and fewer than 100 lives are lost per year. The situation has begun changing in the last decade, however, ostensibly due to global warming and local climatic change such as the heat island phenomenon. The most typical change is the increase in heavy precipitation. Meteorologists sometimes call 1997 the turning point in climate change. The year 1998 was one of extreme heavy rain in Japan, with downpours exceeding 100 mm/h occurring 10 times and those of 50 mm/h almost 440 times. The record for 50 mm/h was broken in 2004, when some 470 such downpours occurred. Another marked change has been the increase in the fluctuation of precipitation, suggesting that drought may follow floods as a typical pattern portending major water disasters in the future. Lifestyle changes are another factor inducing water disaster. Increased urban populations inherently induce concentrated land use, paving of land surfaces, hazardous living conditions, etc. Frequent urban flooding and high underground use in Japan increases the danger for inundations. Wind disasters are also increasing. In September 2006, a tornado in Nobeoka, Kyushu, killed 3 people. In November 2006, another tornado struck Saroma, Hokkaido, killing 9 workers when a construction company's meeting room was destroyed. Polluted material transported long distances by wind is a big problem in Asia. Smoke from forest fires and chemical pollutants increasingly endanger people outside of the countries of origin, spreading throughout the continent and to islands beyond. This issue reviews recent meteorological and hydrographic disasters in urban areas that threaten to become major problems in the 21st Century.

Abstract Background: Anagrelide clinical trials in myeloproliferative neoplasms (MPN) were pioneered by the late Murray N. Silverstein M.D.(1928-1998) of the Mayo Clinic and the first publication involving 20 patients, including 17 with essential thrombocythemia (ET), appeared in 1988 (study launched in October 1985) (N Engl J Med 1988;318:1292). A larger study involving 577 patients, including 335 with ET, was subsequently published in 1992 and led to FDA approval in March 1997 (Am J Med 1992;92:69). Anagrelide has also been evaluated, in controlled studies, for its efficacy and safety as first-line therapy for ET; the results of these studies suggested that anagrelide was not inferior to hydroxyurea, in one study (Blood 2013;121:1720), but might have been harmful to patients in, the second study (N Engl J Med 2005;353:33); in the latter study, patients receiving anagrelide experienced higher incidences of arterial thrombosis, bleeding complications and fibrotic progression. These observations raised significant concern regarding an adverse survival impact of anagrelide in ET; unfortunately, the follow-up period of formal controlled studies were too short to accurately address the particular concern. Methods: The current study represents a retrospective examination of the potential impact of anagrelide therapy on survival and disease complication rates in ET. The study population was recruited from a consecutive cohort of adult patients (age ≥18 years) with MPN seen at the Mayo Clinic from 10/27/1967 through 12/29/2017. Diagnosis and determinations of fibrotic and/or leukemic transformations, were in strict accordance with the 2016 World Health Organization criteria (Blood 2016;127:2391). Statistical analyses were based on clinical and laboratory parameters obtained at the time of first referral to the Mayo Clinic which, in the majority of cases, coincided with initial diagnosis. All patients were followed from diagnosis until death or date of last follow-up or contact. Follow-up was until April 2018 and data collected via medical records or in certain cases, by directly contacting patients or their physicians. Survival and time-to-event curves were prepared using the Kaplan-Meier method and compared by the log-rank test. The JMP® Pro 13.0.0 software package was used for all analyses (SAS Institute, Cary, NC, USA). Results: 1,076 patients with ET were considered (median age 58 years; females 63%); international prognostic scoring system for ET (IPSET; Blood 2012;120:1197) risk distribution was 28% high, 42% intermediate and 30% low; driver mutational status was JAK2 61%, CALR 25%, triple-negative 11% and MPL 3%. Comparison of cases diagnosed before (n=433) and after (n=643) the FDA approval date of anagrelide (1997) revealed the former cohort to be younger (median 57 vs 60 years; p=0.003), although the difference in IPSET risk distribution was not significant (p=0.14). Figures 1a, 1b, 1c and 1d illustrate overall (OS), myelofibrosis-free (MFFS), leukemia-free (LFS) and thrombosis-free survival data comparing ET patients diagnosed before and after the 1997 FDA approval date for anagrelide; a significant difference was apparent for OS (p=0.006; HR 1.4, 95% CI 1.1-1.7) and MFFS (p<0.001; HR 4.2, 95% CI 2.7-6.5), in favor of patients diagnosed prior to 1997; during multivariable analysis that included IPSET and sex, the significant difference in both OS and MFFS were sustained; the difference in OS was most apparent after the first decade of diagnosis with 10- and 20-year survival rates of 75% and 50% for diagnosis prior to 1997 vs 72% and 21% for diagnosis between 1997 and 2017 (figure 1a); the 10- and 20-year risk of fibrotic progression was 3% and 15% for diagnosis prior to 1997 and 14% and 46% for diagnosis after 1997 (figure 1b); there was no impact on LFS (p=0.32; Figure 1c) or TFS (p=0.18; Figure 1d). Similarly stratified survival data in polycythemia vera (n=665) and primary myelofibrosis (n=1,282) showed no impact on survival (p=0.3 and 0.17, respectively). Conclusions: In a retrospective, but otherwise unbiased comparative analysis, we show significantly decreased OS and MFFS in ET patients diagnosed after the FDA approval date of anagrelide (1997); the increased risk of fibrotic progression noted is consistent with results of earlier prospective data (N Engl J Med 2005;353:33). Our observations regarding OS requires confirmation in a prospective controlled setting. Disclosures No relevant conflicts of interest to declare.

Truth and Reconciliation Commission of South Africa Report: Five Volumes, Basingstoke and Oxford, Macmillan, 1999On 29 October 1998 Archbishop Desmond Tutu presented the final report of the Truth and Reconciliation Commission to President Nelson Mandela. This massive report has now been published by Macmillan in a handsome, extensively illustrated five-volume set. The fine quality of the production would seem appropriate to what has been hailed as a document of lasting importance for South Africa. Indeed, it is evident that many foreign commentators see it as important not just for South Africa but for the whole world. That has been reflected in the interest shown in the TRC by commentators, such as Timothy Garton Ash and Michael Ignatieff, who have not previously written about South Africa. The report was the culmination of nearly three years of work by the TRC. President Mandela announced the names of the 17 commissioners (designating Desmond Tutu as chairperson and Alex Boraine as deputy chairperson) in November 1995. It began to function in December that year, while the first public hearings were held on 15 April 1996. However, while the report has been the most significant product of the TRC's endeavours, it is not the end of its work. In particular, the Committee on Amnesty will continue to function until it has reached decisions on all the outstanding applications for amnesty received by the deadline of 30 September 1997. When it has completed this task a further volume of the final report will be published.

ABSTRACT The choice of exchange rate regime is the most relevant decision in the economic world that has to be faced by the economic authority until now. Exchange rate regime that is applied by one country become a controversial debate after the Asia’s crisis in the year 1997-1998, especially for developing countries and emerging economies in Asia. The purpose of this research is to see the impact of export diversification, intensive margin and extensive margin to the choice of the exchange rate regime in nine emerging and developing countries in Asia 1991-2014.This research uses the panel logistic regression model to analyze the two model that are used in the research; they are: model 1 (the impact of export diversification to the exchange rate regime),and model 2 (the impact of extensive margin and intensive margin to the exchange rate regime. To avoid and to lessen the chances of endogeneity problem therefore, all of the independent variables and the control variable must be lagged in one period.The results of the regression shows that export diversification have a significant positive impact on the exchange rate regime. When export diversification is decomposed into intensive margin and extensive margins, the result shows that the extensive margins also have a significant positive impact towards the exchange rate regime, while the intensive margin does not show any significant impact towards the exchange rate regime choice. Keywords: exchange rate regime, export diversification, intensive margin, extensive margin, emerging and developing countries in Asia.

AbstractThe return of the Arabian oryx Oryx leucoryx to Oman symbolized the success of a new approach to species conservation and established reintroduction as a conservation tool. Ten years after the species had been exterminated in the wild by poaching, the first 10 founder oryx, descendants of the ′World Herd′, were reintroduced to the desert in central Oman in January 1982. A second release followed in 1984 and the population grew slowly through a 3-year drought that was broken by rain in June 1986. Further years of good rainfall and more founders meant that by April 1990 there were over 100 oryx in the wild, independent of supplementary feed and water, and using a range of over 11,000 sq km. At that time a new monitoring programme was implemented that allowed the transition from individual- to population-based monitoring and management. The population continued to grow and by October 1995 numbered approximately 280 in the wild (of which 22 were surviving founders) and used over 16,000 sq km of the Arabian Oryx Sanctuary. However, in February 1996 poaching resumed and oryx were captured for sale as live animals outside the country. Despite the poaching the population continued to increase and by October 1996 was estimated to be just over 400. However, poaching intensified and continued through late 1996 and 1997. By September 1998 it had reduced the wild population to an estimated 138 animals, of which just 28 were females. The wild population was no longer considered viable and action was taken to rescue some of the remaining animals from the wild to form a captive herd.

Introduction Infants having a birth weight of 2500g or less are known as low birth weight infants. There are multiple factors which affect the nutritional status of newborn children: genetic potential, maternal age, parity, maternal health and maternal nutrition, drugs, alcohol, smoking, geographical situation and socioeconomic living conditions. Material and methods Developmental parameters were analyzed in 15.455 live newborn infants in Subotica, from 1991 to 2002. The following parameters were registered: body mass in the first hour of life, body length, head and thorax circumference. These parameters were examined and correlated with other indicators of maturity and vitality, such as gestational age and Apgar score values. Results and discussion Parameter mean values are presented for each year from 1991 to 2002. Mean body mass values ranged from 3335.74 g in 1991 to 3418.01 gin 1998. Compared with the estimates provided by World Health Organization, the percentage of newborn infants with birht weight under 2500 g has increased (5.64%) in 1991, which was the first year of war and sanctions in our country. From 1994 to 1997, there was a war in neighbouring republics and a huge number of refugees from war regions arrived. The percentage of newborn infants with low birth weight has increased (the gratest percentage 5.08% has been found in 1996). During 1999, our country was bombed and since then, we have an increased number of newborn infants with low birht weight (4.46% were registered in 1999 to 5.22% in 2002). The number of children born before 37th week of gestation is greatest in 2000 (3.17%). Average Apgar score in 1992 was (9.20), showing graduate decrease since 1999, with lowest value during 2001 (8.85). Conclusion Harmful environmental factors can strongly affect fetal growth. Continual follow-up of developmental parameters and vitality of infants on population level is an index of interactions between genetic potential and environmental factors, pointing to quality of health care and preventive services. .

The paper is focused on a description of the winegrowing and wine-production in Australia, a country, which is becoming a more and more significant producer and exporter of wine in the world, and has become a part of competitive environment of the winegrowing and wine-production industry in the Czech Republic.Structural analysis of external environment is a part of strategic analysis of an industry, where one of the key parts is the analysis of competitive environment within an industry.Winegrowing areas of Australia are nowadays located mostly in the colder climatic zone of Australia. In the 70-ies of the last century, there were planted new vineyards, in these areas, and the grapes from them have started to be used for production of quality-wine and the production of sweet wines and brandies have decreased. The most significant wine-production state has become the South Australia with the sound vineyards around the Murray River. The area of the productive vineyards has doubled, in the past seven years; most of the vineyards are under irrigation. The total grape production in the marketing year 2001–2002 was 1 514 501 t, where 56% were the blue grapes. In the marketing year 2001–2002, there was produced 1 220 mil. litres of wine and 416 mil. litres were exported., whereas in the marketing year 2002–2003 the exports amounted for 508 mil. litres of wine. Most of the wine was exported to the Great Britain – in the marketing year 2001–2002 it was 48% of the total exports. In 2003–2004, were exported to the Czech Republic 466 914 litres of wine, which is an 850% growth within the past four years. The average price of 1 litre of wine imported to the Czech Republic was 2.16 €, in the marketing year 2002–2003, and have grown by 0.28 € in the following year. Wine imports to Australia are decreasing from the marketing year 1997–1998. In the marketing year 2002–2003, the imports were 17 mil. litres of wine, for 81 mil €. Consumption of all alcoholic drinks recounted to the per capita and per year level is decreasing in Australia; from the marketing year 1977–1978 it have fallen by 26% to the year 1999–2000, but the wine consumption have grown by 43.6% in the same period.The paper is a part of solution of a grant focused on analysis and definition of a long-term development concept of the winegrowing and wine production industries in the Czech Republic for the Ministry of Agriculture (NAZV QF 3276), and is also a part of solution of the research plan of FBE MUAF in Brno (GAMSM 431100007).

Abstract Introduction Recently a number of clinical trials have reported on a comparison between autologous stem cell transplantation (ASCT) for multiple myeloma (MM) versus conventional dose therapies. These studies have shown that even in the era of "novel agents", early ASCT is associated with significant improvements in progression free survival (PFS). Further a recent population based study has suggested that having received ASCT is one of the most important prognostic factors governing long-term outcomes for patients with MM. These observations prompted us to examine the long-term outcomes achievable in a series of ASCT patients where novel agents were incorporated into patient management and how these outcomes have changed over time. Methods To investigate long-term survival, we followed patients with newly diagnosed MM who received an ASCT at the University of Arkansas for Medical Sciences (UAMS) Myeloma Institute, from 1989 to 2018. Patients with smoldering myeloma, and those who did not receive an ASCT were excluded from the study. In addition to ASCT, patients who were enrolled on a clinical trial received experimental chemotherapeutic regimens determined by the clinical trials protocol being implemented at the time. All other patients received standard therapies appropriate at the time of diagnosis. Based on the year of their first ASCT, patients were separated into time periods that roughly corresponded to the dates of different protocols when novel agents were being tested at UAMS (1997 or earlier [reference group], 1998-2003, 2004-2008, 2009-2013, and 2014 or later). Kaplan-Meier curves with log-rank tests, and Cox proportional hazards models adjusting for age, sex and race/ethnicity were used to evaluate survival during the different time periods. Because the demographics of the UAMS patients have changed over time (with older and non-White patients becoming more common in more recent years), we also explored approaches to correct for temporal changes in both MM patients at UAMS and within the general US population, including a Fine-Gray competing risk analysis, and a relative survival analysis using SEER life tables to account for population differences in mortality by age, year, sex, and race/ethnicity. Results A total of 4,326 MM patients met the eligibility criteria for this study, with 2,465 patients enrolled on a clinical trial. The median follow-up time was 10.4 years, with median overall survival of 6.9 years. In the adjusted Cox proportional hazards model, patients who had their first ASCT in 2014 or later had significantly improved survival compared to those who had their first ASCT in 1997 or earlier (HR, 0.32; 95% CI, 0.25-0.41). Among patients who had a valid cause of death (n=2961), Fine-Gray competing risk analyses confirmed this finding (HR, 0.10; 95%CI, 0.05-0.19). After using SEER life tables to correct for differences in normal mortality, we find less relative excess risk (RER) for MM death with each successive time period compared to the "1997 or earlier" reference group: 1998-2003 (RER, 0.67; 95%CI, 0.57-0.78), 2004-2008 (RER, 0.56; 95% CI, 0.48-0.66), 2009-2013 (RER, 0.56; 95% CI, 0.47-0.66), 2014 or later (RER, 0.31; 95% CI, 0.22-0.42). These results suggest that as chemotherapeutics and patient management strategies have changed over time, the MM survival has steadily and consistently improved at UAMS. Conclusions Our results suggest that after correcting for population differences in mortality by age, sex, year, and race/ethnicity, MM survival in UAMS patients has improved over time. These trends could be due to a number of factors, including improvements in MM therapies, risk stratification models, management of older patients, and increased understanding of MM biology and meaningful prognostic factors. Additional analyses to examine these traits, and Cure-Rate survival models to determine the likelihood of achieving long-term disease-free survivorship, are currently ongoing. Disclosures Davies: MMRF: Honoraria; ASH: Honoraria; Abbvie: Consultancy; Amgen: Consultancy, Membership on an entity's Board of Directors or advisory committees; Celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Janssen: Consultancy, Honoraria; Takeda: Consultancy, Membership on an entity's Board of Directors or advisory committees; TRM Oncology: Honoraria. Barlogie:European School of Haematology- International Conference on Multiple Myeloma: Other: travel stipend; ComtecMed- World Congress on Controversies in Hematology: Other: travel stipend; Myeloma Health, LLC: Patents & Royalties: : Co-inventor of patents and patent applications related to use of GEP in cancer medicine licensed to Myeloma Health, LLC; Multiple Myeloma Research Foundation: Other: travel stipend; Dana Farber Cancer Institute: Other: travel stipend; Millenium: Consultancy, Research Funding; International Workshop on Waldenström's Macroglobulinemia: Other: travel stipend; Celgene: Consultancy, Research Funding. Morgan:Celgene: Consultancy, Honoraria, Research Funding; Takeda: Consultancy, Honoraria; Bristol-Myers Squibb: Consultancy, Honoraria; Janssen: Research Funding.

Climate change is one of the most complex and crucial issues in the world. It has impacted environmental, social, and economic sectors of our planet. Unsurprisingly, Nepal is not immune to climate change. In fact, it is one of the most susceptible countries to climate change. One of the most impacted variables in Nepal due to climate change is the maximum temperature. The rate of change of temperature per year, in Nepal is ever-increasing. This paper examines the temperature trend and how it has affected environmental, social, and economic sustainability of Kaski District in Nepal. The paper utilizes the maximum temperature trend of Kaski District during 1970-2018. The monthly minimum and maximum temperatures are obtained from the Department of Hydrology and Meteorology (DHM). The study is done based on the data obtained from Pokhara Airport and Lumle stations. The paper uses three statistical tools alongside descriptive statistics to analyze the data. First, the Man-Kendall test is used to figure out the trend of temperature. Second, Sen’s slope is used to find the magnitude of a trend. Third, the Time series model has been used for forecasting temperature trends. Finally, SPSS and R software were used to calculate the results. The trend of maximum temperature has been significantly increased in Kaski District. The maximum temperature in Kaski during 1970-2018, recorded, was 24.99°C in 2005 and was closely followed by 24.66°C temperature in 2010. The average maximum temperature during the 1970-2018 period was 23.49°C. The maximum variation of maximum temperature during 1970-2018 was in 1992 with a standard deviation of 5.94°C. The minimum temperature during 1970-2018 was 21.12°C in 1978 and was closely followed by 22.19°C in 1997. There is an increasing trend of maximum temperature in Kaski District. In addition, the trend of maximum temperature is higher and faster after 1998 in Kaski District of Western Nepal during 1970-2018.

Background: Several population-based studies on multiple myeloma (MM) have shown an improvement in relative survival (RS) for patients aged 65 years or younger at the time of diagnosis. In patients aged 75 years or older, the improvement in long-term RS is absent in most reports or much less pronounced. To our knowledge, only 2 studies based on the Surveillance, Epidemiology and End Results (SEER) database have demonstrated a significant increase in RS for this age-group. (Pulte et al. 2011, Costa et al. 2017) We performed a population-based study on Norwegian MM-patients to provide up-to-date estimates on changes in relative survival during the past 3 decades. Methods: The Cancer Registry of Norway (CRN) was established in 1951 and provides high-quality nationwide cancer statistics. For MM, the reported completeness of case-ascertainment is above 95%. Incidence data and all reported cases of MM diagnosed between January 1, 1982 and December 31, 2017 were retrieved from the CRN (n=10 961). Nationwide drug consumption statistics for drugs used in myeloma treatment were retrieved from the Norwegian Drug Wholesales Statistics and the Norwegian Prescriptions Database, Norwegian Institute of Public Health. Follow-up ended December 31, 2017. The time of MM-diagnosis was divided into 7 categories: 1982-1987, 1988-1992 (melphalan-prednisone), 1993-1997(early high-dose melphalan with autologous stem-cell transplant (HDM-ASCT)), 1998-2002 (introduction of thalidomide), 2003-2007 (early thalidomide upfront, introduction of bortezomib), 2008-2012 (thalidomide and bortezomib upfront, introduction of lenalidomide), 2013-2017 (lenalidomide upfront, early pomalidomide, daratumumab, panobinostat and carfilzomib). Age at diagnosis was divided into 3 categories; <65 years, 65-79 years and 80 years or older. We estimated relative survival ratios (RSR) with 95% confidence intervals 5 and 10 years after the time of diagnosis by the Ederer-II method. The analysis was stratified by age-group and calendar period of diagnosis. Cohort analysis was applied to calendar periods with complete follow-up, and period analysis was applied where complete-follow up was not available (2013-2017 and 10-year estimates for 2008-2012). Non-overlapping confidence intervals were considered statistically significant. Results: The age-standardized incidence rate was stable until approximately year 2000, followed by an increasing tendency reaching 8.4 cases per 100 000 persons in 2017. Figure 1. Patients diagnosed before the age of 65 had a steady increase in both 5 and 10-year RSR across all calendar periods. For patients aged 65-79 years, the 5- and 10-year RSR's were stable at approximately 0.3 and 0.1, respectively, until the calendar period 1998-2002. In the following years, an improvement in both 5- and 10-year RSR was observed. The 5-year RSR improved significantly from 0.31 (95% CI; 0.27-0.35) in the first calendar period to 0.43 (95% CI;0.39- 0.47) during 2008-2012. The predicted 5-year RSR for 2013-2017 was 0.48 (95% CI; 0.44-0.52). There were also signs of improved 10-year RSR, predicted to 0.23 (95% CI; 0.18-0.27) during 2013-2017 compared to 0.11 (95% CI; 0.08-0.14) during 1982-1987. The 5-year RSR for patients aged 80+ years was 0.11 (95% CI; 0.01-0.17) during 1982-1987 and the 10-year RSR was 0.03 (95% CI; 0.01-0.11). In the following 4 calendar periods the RSR-estimates fluctuated before a rising tendency during the last 2 periods. The 5-year RSR improved significantly to 0.26 (95% CI; 0.20-0.32) during 2008-2012 and further rising to a predicted value of 0.32 (95% CI; 0.25-0.38) during 2013-2017. Figure 2. Additionally, complete annual prescription statistics for the oral agents thalidomide, lenalidomide and pomalidomide were obtained. Conclusions: We provide real-world observations on changes in RS in a population-based cohort of 10 961 MM-patients. We demonstrate an improvement in 5-year relative survival across all age-groups, including patients aged 80 years or older. For patients <65 years, there was a steady increase in RS since 1982 and we see no obvious impact of the implementation of HDM-ASCT. For the other age-groups, the improvement in RS coincides with the introduction of new drugs. The increase in incidence since 2000 may be due to increased testing for M-protein. We can point to the introduction of new drugs and increased incidence of indolent cases as possible reasons for increasing RS. Disclosures No relevant conflicts of interest to declare.

Purpose The main aim of this paper is to provide an overview of the most influential economic changes and accounting legislation affecting financial reporting and disclosure practices in Jordan. It also provides an overview of disclosure studies conducted in Jordan covering the year(s) between 1986 and 2014 to investigate whether there is an improvement in disclosure practice in Jordan. This paper also investigates the most influential firm characteristics affecting disclosure practices in Jordan found in prior disclosure studies that were conducted in Jordan between 1986 and 2014. The paper also addresses the disclosure items required in Corporate Governance Codes that exist for listed shareholding companies, banks and insurance companies. Finally, the paper discusses the quality of accounting education in Jordan, as prior studies noted its impact on accounting practice. Design/methodology/approach Based on a review of prior disclosure studies conducted in Jordan between 1986 and 2014, this study compared the results of disclosure studies before and after 1998. In 1997, Jordan, as a result of economic changes, issued the Temporary Securities Law and its Directives of Disclosure, which came into effect in 1998. The law is considered as the turning point in the improvement of disclosure practice in Jordan. A trend line of disclosure practice is also used to investigate whether disclosure practice is improved after the issuance of this law. A descriptive analysis is also used to examine the factors affecting disclosure practice in Jordan. Findings Based on a review of prior disclosure studies, it was concluded that disclosure practices have improved overtime. It was also observed that that firm size as a factor has always affected the level of disclosure in Jordan and is followed by external auditing, while liquidity is found to have the least effect. It was concluded that economic changes, agreement with international organizations like the World Trade Organization (WTO) and the International Organization of Securities Commissions (IOSCO), new regulations and financial market reforms have improved disclosure practice in Jordan. It was also found that there is a need for further studies in disclosure practice that are not sufficiently covered in Jordan. Originality/value The study is based on a review of disclosure studies conducted in Jordan between 1986 and 2014. We investigate whether mandatory, voluntary, corporate social and internet disclosure practice improved over the last three decades in Jordan. This study is the first to provide evidence on the improvement of disclosure practices based on a review of disclosure studies in Jordan. The paper is expected to be a reference for disclosure studies in developing countries, Jordan in particular, as it summarized and criticized the weaknesses on disclosure practice and accounting legislations in Jordan.

Abstract Reducing costs associated with pest management in peanut (Arachis hypogaea L.) production systems in the United States will become increasingly important due to changes in federal legislation that reduced support prices and removed the escalator provision. The federal peanut program may be eliminated completely in 2002 at which time peanut most likely will be marketed at the world price, which is substantially lower than the current quota price. Eight experiments were conducted during 1997 and 1998 to evaluate pest control, pod yield, gross value, and economic return with preventive and integrated pest management (IPM)-based disease, insect, and weed management strategies. Preventive strategies included prophylactic applications of herbicides, fungicides, fumigant, and insecticides. IPM strategies involved host-plant resistance, targeting pesticide applications based on economic thresholds, and other thresholdbased practices to manage pests. Preventive and IPM weed management strategies provided similar economic return in seven of eight experiments. Early leaf spot, caused by Cercospora arachidicola, control was similar when fungicides were applied biweekly or based on weather advisories. However, scheduling fungicide sprays using weather-based advisories eliminated one to three fungicide applications per year. Biweekly applications of fungicides increased damage from twospotted spider mite (Tetranycychus urticae) in one experiment compared with applications using weather-based advisories. Fumigation by metam sodium for Cylindrocladium black rot (CBR), caused by Cylindrocladium crotalarie, was needed in one of three experiments where this disease was present. Resistance of the cultivar NC 12C to CBR was not sufficient to prevent yield and economic loss where damage exceeded 10% plant loss. Iprodione was applied preventatively for suppression of Sclerotinia blight, caused by Sclerotinia minor. However, this disease developed in only one of four experiments where fungicide was applied. Aldicarb applied infurrow and acephate applied postemergence based on damage thresholds controlled tobacco thrips (Frankliniella fusca) similarly in seven of eight experiments. In one experiment, aldicarb was more effective than acephate. Failure to apply chlorpyrifos for southern corn rootworm (Diabrotica undecimpunctata) control resulted in yield and economic loss in three experiments. Chlorpyrifos controlled potato leafhopper (Empoasca fabae) and prevented possible yield loss caused by this insect. Collectively, these data demonstrate the complexity of pest management in peanut and some of the weaknesses associated with current pest control and IPM practices. The importance of accurate identification of pests and detailed field histories also was demonstrated in these studies. Likewise, a thorough understanding of the impact of production practices on pest development and timely implementation of pest control tactics is critical for adequate plant protection.

Мета цього дослідження – проаналізувати можливість використовувати погляди Р. В. Ленекера на когнітивну семантику як семантико-текстологічну модель перекладознавчого аналізу. Матеріалом для розгляду обрано твір «Слово некоего калугера о чьтьи книг» із «Ізборника Святослава» 1076 р. та його три переклади: два переклади сучасною українською мовою (повний – В. Яременка, частковий – Є. Карпіловської й Л. Тарновецької) та один переклад англійською мовою (В. Федера). Теорія когнітивної семантики Р. Ленекера орієнтується здебільшого на граматичні проблеми й опис мови через параметри простору. Параметрам опису образности, які пропонує когнітивна семантика, бракує чіткости, які мають аналітичні методи структуралізму. Однак, вони виконують головну аналітичну функцію: вони дозволяють усвідомити наявні в перекладі порушення й відхилення від першотвору та намагатися усвідомити їхню природу й межі.
 Література
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This study analyzes the level and structure of old age population mortality in Yugoslavia with an aim to determine the intensity of realized changes and to provide an answer to how much they are significant and to approach the positive trends noted in developed countries in the latest period. Although it was insufficiently represented in the demographic analysis, the analysis of mortality in old people is gaining importance in the world. Apart from the reasons which result from the increase in the number of old people and thus their greater participation in the total number of deceased, enviable results have been achieved in decreasing old age mortality, which are more and more in focus of interest. While earlier research reported on the dominant influence of the decrease of younger age mortality to the increase of the expectation of life at birth, recent analysis precisely confirm the importance of decreasing mortality in old people. In mortality conditions from 1997/98, an additional 13.4 years of life in average is expected for men in Yugoslavia, and 15.2 for women. During more than five decades, the anticipated life expectancy for people over the age of 65 increased for only 1.2 years for men and 1.9 years for women. Out of that, the greatest increase was realized in the period 1950/51 - 1960/61 in both sexes. A small decrease in the average life expectancy was marked with men in the period 1960/61 - 1970/71, and with women in the latest period. Otherwise, all up to the eighties, the annual rate of increase was considerably lower than the rate of increase for zero year. It was only in the period 1980/81-1990/91 that faster growth had an anticipated life expectancy for the 65 years old. However, during the nineties unfavorable changes continued with the older, especially, female population. When comparing the values of the average life expectancy for people over 65 in Yugoslavia with corresponding values in developed countries, the lagging in average amounted to about 3 years for the male and about 5 years for the female population. In Japan in 1998 it amounted to 17.1 years, namely 22.0 years respectively. However, it is interesting that all up to the seventies these indexes were almost at the same level in our country and Japan, and only after this period the differences appeared as a consequence of putting an end to the positive tendencies in differential mortality by age, even in the increase rate with the older population in Yugoslavia. On the other hand, the anticipated life expectancy for the age of 65 (for both sexes) was increased by 40%, in Japan from 1970 to 1998, in contrast to an increase of 9% for 0 age. In the same period in Yugoslavia, although there was a considerably lower increase percentage, it was still more significant with newborns (above 6% for both sexes), than with population older than 65 (under 5%). Hence, such an inclination and intensity of changes resulted, in relation to Japan, in a relatively greater lagging with people aged 65 than with 0 age. The anticipated life expectancy for people aged 85 and over, in the whole observed period, increased only by 8% with the male population and 10% with the female population of Yugoslavia. Its present level is the result of small changes in the mortality rates of the oldest population. In average, people aged 85 + will live another 4.2, namely 4.4 years respectively under the assumed mortality from 1997/98. At the same time the Japanese men are expected to live another 5.4, and Japanese women another 7.2 years. Therefore, middle aged and old population in Yugoslavia has had unfavorable mortality tendencies in relation to the young population, more distinct beginning from the seventies, and especially with men. The nineties were again unfavorable for the old population, this time especially for the female population, where a slight decrease of this rate was marked. Having in mind the changes and achieved level of anticipated life expectancy in developed countries, it can be said that the deviations in relation to the rates in our country are significant, relatively greater with the older population. For this reason, mortality reduction of the old age population is a chance for an increase in the life span, although all possibilities in our country, for the decrease of mortality with the young as well, especially newborns, have not been exploited. In that sense, it seems that the greatest importance would be control of cardiovascular illnesses and risk factors regarding individual behavior.

The article presents the semantic history of the word flapper that denotes social stereotype of American culture. Being a multifaceted phenomenon of semantic cognition, a sociocultural stereotype presents a condensed and coded information that develops on the background of a cultural context. The semantic analysis from diachronic perspective sets up a correspondence of Latin origin of the word flapper with Indo-European stem that produced a number of words in Germanic languages. The cognate words of related languages reveal conformity of negative connotations determined by attitude to human weakness in different forms of its manifestations. This presumes historically determined negative connotation of the word flapper. The initial designation was motivated by kinetic characteristic of the object – a vertical movement. The meaning “a young and daring American girl of the 1920s” of the word flapper was semantically motivated. As it was stated, at the moment of designation, youth and immaturity of a girl were conceived of a fledgling image, that traditionally symbolizes inexperience of a youngster. This zoomorphic metaphor acts as the source of categorization of a cultural and social phenomenon “Flapper”.
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Veronica sibirica (Veronicastrum sibiricum) is an erect perennial herb, an ornamental, and a traditional Chinese medicine plant distributed mostly in northeastern, northern, and northwestern China. It has dehumidifying and detoxifying properties, and is mainly used for the treatment of cold, sore throat, mumps, rheumatism, and insect bites (4). In June 2008 through 2012, leaf spots of V. sibirica were observed in the Medicinal Herb Garden of Jilin Agricultural University (43°48′N, 125°23′E) and the medicinal plantations of Antu County (43°6′N, 128°53′E), Jilin Province. Leaf spots were amphigenous, subcircular, angular-irregular, brown, and 1 to 10 mm in diameter; they occasionally merged into a larger spot with an indefinite margin or with a pale center and dark border. Pale conidiomata were hypophyllous and scattered on the spots. The conidiophores were 100 to 400 μm high and clustered together to form synnemata 20 to 50 μm in diameter, which splayed out apically and formed loose to dense capitula. Conidiophores occasionally emerged through the stomata individually and produced conidia on the surface of the infected leaves. The conidiogenous cell terminal was geniculate-sinuous with somewhat thickened and darkened conidial scars. Conidia were solitary or catenulate, ellipsoid-ovoid or subcylindric-fusiform, hyaline and spinulose, 4.01 to 7.18 × 11.16 to 20.62 μm with obtuse to somewhat attenuated ends, and slightly thickened, darkened hila. Six isolates were obtained from necrotic tissue of leaf spots and cultured on potato dextrose agar at 25°C. After incubation for 14 days, colony surfaces were white to pinkish. The colony diameter increased by 12 mm after 21 days' incubation. Hyphae were hyaline, septate, and branched. Conidiophores grew individually or fascicularly. The symptoms and morphological characteristics were consistent with previous descriptions (1,2), and the fungus was identified as Phacellium veronicae (Pass.) (U. Braun 1990). The internal transcribed spacer (ITS) region of the nuclear rDNA was amplified using primers ITS4/ITS5 (3). The ITS was identical among all six isolates (HE995799) and 98% identical to that of P. veronicae (JQ920427, HQ690097). Pathogenicity was confirmed by spraying five 1-year-old V. sibirica seedlings with a conidial suspension (106 conidia/ml) of each isolate and five seedlings with sterile water as a control treatment. Plants were grown in the greenhouse at 20 to 25°C and were covered with plastic bags to maintain humidity on the foliage for 72 h. After 15 days, the same symptoms appeared on the leaves as described earlier for the field-grown plants; the control plants remained healthy. The same fungus was reisolated from the leaf spots of inoculated plants. Currently, the economic importance of this disease is limited, but it may become a more significant problem, as the cultivated area of V. sibirica is increasing. To our knowledge, although P. veronicae was recorded on the other species of Veronica (V. austriaca, V. chamaedrys, V. grandis, V. longifolia, V. paniculata, and V. spicata ssp. incana) in Europe (Germany, Denmark, Ireland, Romania) and V. wormskjoldii in North America (Canada) (1), this is the first report of V. sibirica leaf spots caused by P. veronicae in the world, and it is a new disease in China. References: (1) U. Braun. A monograph of Cercosporella, Ramularia and allied genera (phytopathogenic Hyphomycetes) 2, IHW-Verlag, Germany, 1998. (2) U. Braun. Nova Hedwigia 50:499, 1990. (3) D. E. L. Cooke et al. Mycol. Res. 101:667, 1997. (4) Jiangsu New Medical College. Dictionary of Chinese Materia Medica. Shanghai: Shanghai Scientific and Technical Publishers, China, 1977.

Abstract Background Insight in schizophrenia spectrum disorders (SSD) has been linked with positive outcomes. However, the effect size of previous treatments on insight has been relatively small to date. The metacognitive basis of insight in SSD has led to speculation that metacognitive training (MCT) may improve insight and clinical outcomes in SSD. Methods Design: Single-center, assessor-blind, parallel-group, randomised controlled trial (RCT). Sample: Participants are recruited from the outpatient clinic of Hospital Universitario Fundación Jiménez Díaz (Madrid, Spain) over June-December 2019. Inclusion criteria: i) age: 18–64 years, both inclusive, at the study inception; ii) diagnosis: SSD based on the Mini International Neuropsychiatric Interview (Sheehan et al., 1998) and iii) IQ>70 according to the Wechsler Adults Intelligence Scale-IV (Wechsler, 1981). Those with organic and drugs-induced psychosis, poor level of Spanish and/or lack of cooperativeness are excluded. Intervention: Participants are randomised to receive eight weekly group sessions of MCT or group psychoeducation (PSE) and they will be assessed at: T0) at baseline; T1) after treatment and T2) at 1-year follow-up, although follow-up data are not available yet. Co-primary outcome measures: clinical and cognitive insight dimensions, which will be measured by the Schedule for Assessment of Insight (Expanded version) (SAI-E) (Kemp & David, 1997), and the Beck Cognitive Insight Scale (BCIS) (Beck et al., 2004), respectively. Secondary outcome measures: i)Symptom severity-Positive and Negative Syndrome Scale (Kay et al., 1987); ii)Functioning-General Assessment of Functioning (Endicott et al., 1976), World Health Organization Disability Scale (WHO, 2012) and Satisfaction Life Domains Scale (Carlson et al., 2009), and only at follow-up (T2) iii)Suicidal Behaviour and iv) Hospitalizations. Power calculations: To reach a power of β=80% and detect a between-group difference of two points on the SAI-E total scores, which is considered to be clinically meaningful -effect size of 0.33-, the estimated sample size at the end of the study is n=126. Statistics: Student’s T-test and Mann-Whitney U tests were used as appropriate to compare between-group differences before- and after-treatment, i.e., the changes from baseline to post-treatment scores. The protocol of the study is registered at ClinicalTrials.gov (NCT04104347). Results n=49 subjects have been assessed at baseline so far (26 males, age: 47.0±10.2 years, diagnosis of schizophrenia -F20-ICD10-, n=36, 73.5%). Fifteen individuals (MCT: n=8; controls: n=7) have completed the treatment and the post-treatment assessment (T1). ‘After-treatment-T1 - baseline-T0’ scores difference means/medians between-group differences (MCT vs. PSE) were: SAI-E total insight 1.00 vs. -2.00, p=0.050; SAI-E illness awareness 0.62±2.20 vs. -0.43±1.62, p=0.316; SAI-E symptom relabelling 0.37±3.38 vs. -1.86±2.34, p=0.167; SAI-E treatment compliance 0.00 vs. 0.00, p>0.05,ns; BCIS self-reflectiveness 0.50±3.78 vs. -1.43±2.22, p=0.259, BCIS self-certainty 1.62±2.97 vs. 0.00±2.44, p=0.298 and BCIS Composite Index -1.13±5.62 vs. -2.17±3.49, p=0.698. Discussion This is the first RCT testing the effect of group MCT on insight (as primary outcome) in a sample of unselected patients with SSD in comparison with psychoeducation. Two main findings emerged from the results. First, MCT appears to improve clinical and cognitive insight in SSD. Second, MCT was shown to be superior to PSE in changing insight. Whether the above MCT-related insight improvement is maintained at longer-term and whether this has an impact on clinical and social outcomes are yet to be established, which will be properly looked at in this trial.

RESUMENDe entre todos los objetos, tiempos, espacios, palabras y seres que componen el mundo físico, algunos están investidos de un valor especial por cuanto se les atribuye la virtud de visibilizar las instancias invisibles de las que dependemos los mortales. Es lo sagrado. A lo sagrado se le depara un trato singular hecho de respeto, veneración o miedo, pero en ocasiones también de rencor y de odio por lo que encarna o representa. Es adorado, pero también, y acaso por las mismas razones, puede ser insultado, destruido, objeto de burla y, si tiene forma humana, martirizado o asesinado. La violencia contra lo sagrado puede caber en sistemas religiosos que le otorgan a la agresión un papel central en su universo mítico o ritual. También se ofende u agrede lo santo para grupos o pueblos a someter, puesto que en ello está resumido su orden del mundo. Desde esta perspectiva, el agravio, la irreverencia y el daño pasan a reclamar un lugar protagonista en los estudios sobre la institución religiosa de la cultura bajo las figuras del sacrilegio y la profanación.PALABRAS CLAVE: sagrado, profanación, sacrilegio, violencia religiosa, iconoclastia.ABSTRACTOf all the objects, times, spaces, words and beings that make up the physical world, some are invested with a special value because they are attributed the virtue of making visible the invisible instances on which we mortals depend. This is the sacred. The sacred is given a singular treatment combining respect, veneration or fear, but sometimes also resentment and hatred of what it embodies or represents. It is adored, but also, and perhaps for the same reasons, it can be insulted,destroyed, mocked and, if it has a human form, martyred or killed. Violence against the sacred can fit into religious systems that give aggression a central role in their mythical or ritual universe. 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The paper presents the process of language socialization and acquisition of grammatical categories through the Roma oral culture in which metaphors are extensively used. Roma children who grow up in extended Roma families and community learn the language through communication with speakers of different registers. Research with 22 Roma children between three and six years of age from Croatia was carried in order to find out what grammatical categories are learned in this period of the life of children. The children were tested with a specially designed language assessment test in Romani (Kyuchukov & de Villiers, 2014b). The results show that Roma boys perform the test much better than Roma girls. Boys learn Romani from folkloristic genres which are rich in metaphors and this helps them to acquire complex grammatical categories.
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As you may know from recent e-mail, BUSEFAL Vo1.76, Obituary, and Fuzzy Sets and Systems (FSS), Vo1.104, No.2, Obituary, Prof. Ernest Czogala passed away on October 8, 1998. First, I would like to express my sincere condolences to his eldest daughter Theresa Czogala-Koczy and son. The call for papers for this special issue has been answered from all over the globe. This issue includes the first seven accepted. The next issue will include those remaining. Since a formal obituary was provided by Professor Witold Pedrycz, a student of Ernest, in FSS as indicated above, I will add a few words of my own here. I first met Prof. Czogala when I was a visiting professor at the University of Alabama at Birmingham (UAB) Department of Computer and Information Sciences in 1990-1991. He was visiting the Mathematics Department, working with Professor James J. Buckley. When I first met Ernest, I intuitively felt that he, Jim (Prof. Buckley), and I would accomplish outstanding work in the near future. I promised to invite Ernest and Jim to Ibaraki University Department of Computer and Information Sciences in summer 1991. After my sabbatical at UAB, I received a letter from Ernest, asking, "Could I really visit your university for a month?" I immediately sent a formal invitation letter to Ernest and Jim. Ernest purchased an airline ticket between Poland and Japan - a princely sum equal to 6 months of his salary! He arrived August 19, 1991, at Narita Airport around 07:30 aboard All Nippon Airways from Poland via Wien. I drove a Toyota Camry to Narita from Hitachi City, Ibaraki Prefecture - a 2.5-hour excited jaunt. My wife Madoka and I went to pick him up. He appeared easygoing, shod in flip-flops. Madoka and I took him to Narita-san Temple - and found he had only 50 DM with him! After spending a few hours at Narita-san and eating lunch, Jim arrived from Birmingham. We picked him up and returned to Hitachi. Ibaraki University has a very old-fashioned guesthouse - but it only cost 700 a day. The next day, a coup d'etat shook Moscow. Ernest applauded, saying "Poland will be free." From that day, we started our cooperative research in an un-air-conditioned office at Ibaraki University Department of Computer and Information Sciences. Outside, it was over 35°C, which made it 38°C in the office. During his stay, we wrote many papers. One recently appeared carefully selected based on the Science Citation Index, "On the Equivalence of Neural Nets and Fuzzy Expert Systems," FSS, Vol. 100 Supplement, pp. 145-150 (1999). This short proof paper was outstanding. The original paper was submitted to Professor H.-J. Zimmermann, Founding Editor of FSS, in 1991. The paper was soon revised, accepted for publication in 1992, and published January 25, 1993. We have published many journals and refereed International Conference papers. I recollect papers worked on with Ernest. They include: 1. Hayashi, Y, Buckley, J.J. and Czogala, E., Systems Engineering Applications of Fuzzy Neural Networks, Journal of Systems Engineering, Vol.2, pp.232-236 (1992). 2. Buckley, J.J., Hayashi, Y and Czogala, E., On the Equivalence of Neural Nets and Fuzzy Expert Systems, Fuzzy Sets and Systems, Vo1.53, No.2, pp.129-134 (1993). 3. Hayashi, Y, Buckley, J.J. and Czogala, E., Fuzzy Neural Network with Fuzzy Signals and Weights, International Journal of Intelligent Systems, Vol.8, pp.527-537 (1993). In 1995, Ernest came to Yokohama, Japan, to present his paper at FUZZIEEE/IFES'95. Madoka, my 2-year-old son Yuichiro and I met him and ate Chinese lunch together. We promised to meet again. In 1997, I met him again at Barcelona for FUZZ-IEEE'97. He asked about the amount of grants I had applied for. I replied 700 million for three years. "That's beyond all belief!" Unfortunately, my request was not met... Ernest, Jim, and I would have liked to have a delicious beer commemorating the FSS Vo1.100 Supplement. But although we never got to share that beer, the papers - the fruit of great efforts - never died. I believe our publication will continue to be referenced by many researchers all over the world. The FSS paper also symbolizes the position of associate professor for me at Ibaraki University. I was 34 years old at the time. Those of you wanting to get in touch with Ernest's oldest daughter are asked to send inquiries to the following address: Theresa Czogala-Koczy ul. Kochanowskiego 29-15 44-100 Gliwice, Poland We thank Drs. Toshio Fukuda and Kaoru Hirota, Editors in Chief of the JACI, for accepting my proposal for this special issue. Special thanks also go to the referees for their kind cooperation, devotion, and rigorous review! We also thank Mr. Yasushi Inoue for his excellent management of the editorial work.

Abstract. This paper offers three interdependent contributions to studies of climate variation: (1) the recognition and analysis of an intrinsic millennial oceanic oscillation that affects both Northern and Southern high latitude climates, (2) The recognition of an oceanographic switch to ice-free seas west of Greenland that explains the initiation of the Last Ice Age, and (3) an analysis of the effect of increasing salinity in the seas east of Greenland that suggests the possibility of the initiation of an ice age threshold climate in the near future. In the first contribution the millennial oscillation in the flow of the North Atlantic Drift reported by Bond et al. (1997) is proposed to be part of a 1500 yr intrinsic deep ocean oscillation. This oscillation involves the exchange of North Atlantic intermediate-level deep water (NADW) formed in the seas east of Greenland with Antarctic Bottom Water formed in a shallow-water zone at the edge of the Antarctic continent. The concept of NADW formation is already well known, with details of the sinking water flowing out of the Greenland Sea observed by Smethie et al. (2000) using chlorofluorocarbon tracers. The concept of Antarctic Bottom Water formation is also already well established. However, its modulation by the changing fraction of NADW in the Southern Ocean, which I infer from the analysis of Weyl (1968), has not been previously discussed. The modulated lower-salinity Antarctic Bottom Water that reaches the northern North Atlantic then provides negative feedback for the cyclic variation of NADW formation as proposed here. This causes the 1500 yr bipolar oscillation. The feedback suggests the possible sinusoidal character of the proposed oscillation model. The model is consistent with the cooling of the Little Ice Age (Lamb, 1972, 1995), and it also correctly predicts NASA's observation of today's record maximum area of winter sea ice on the Southern Ocean and the present observed record low rate of Antarctic Bottom Water production cited by Broecker (2000). The sinusoidal form of this conceptual model is therefore reinforced by both old and new data, and provides insights into world-wide climate change. The second contribution of this paper is a hypothesis for the initiation of Pleistocene ice ages, typified by the Last Ice Age that began 120 000 yr BP. Instead of the classical Northern high-latitude summer cooling caused by orbital precession and changes in Earth's axis inclination, this hypothesis proposes the sudden onset of year-round ice-free seas west of Greenland, with greatly increased precipitation in the ice sheet nucleation regions of Baffin Island, northern Quebec, and Labrador. Devon Island ice-core studies by Koerner at al. (1988) and deep-sea sediment data reported by Fillon (1985) support the concept of ice-free seas west of Greenland and imply the initial meteorological conditions that are proposed here. These conditions are consistent with the heavy precipitation inferred by Adkins et al. (1997) from deep-sea sediment data. The changes in northeastern Canada were accompanied by quite cold conditions in northern Europe, inferred by Field et al. (1994) from tree pollen data. The European cooling was probably caused by loss of the recurring Iceland low-pressure system due to the dominant effect of a frequent stronger low-pressure system over the Labrador Sea, as postulated in this paper. The key to ice-free seas west of Greenland is the loss of the near-surface stratification that normally enables sea ice to freeze. Using the high-resolution European Space Agency's ENVISAT system, I have monitored the flows through the Nares Strait and found that the dominant southward flow of lower density polar water into Baffin Bay correlated with the growing area of seasonal sea ice forming early in the winter in the Bay near the southern end of the Strait. This implies that low-salinity polar water was the cause of the stratification. A search for the cause of the stratification loss then became a search for the cause of the loss of the southward flow of polar water. The loss could have occurred if denser and more saline Atlantic water replaced the polar water in-flow. Medieval historical records suggest that an analogous partial replacement probably did occur during the early medieval climatic optimum, with some warmer Atlantic water removing the thick perennial sea ice along Greenland's north coast. The NADW formation rate and the Spitsbergen-Atlantic Current (SAC) flow were then near maximum values. I hypothesize that enough of the thick perennial sea ice along Greenland's north coast was removed by the penetration of the SAC flow into the polar ocean to enable a medieval voyage eastward along the coast in AD 1118. This voyage is implied by an old map record showing Greenland realistically as an island. An even stronger SAC flow associated with a stronger maximum in the 1500 yr intrinsic oscillation of the oceanic system was the likely trigger for the initial conditions of ice-sheet growth when the Last Ice Age began. The third contribution of this paper is the hypothesis that modern society's activities might cause a repetition of the transition to an ice age threshold climate within one or two decades from 2013. This possibility depends on a continuing increase of salinity in the seas east of Greenland, with a corresponding increase of NADW formation and the SAC flow. The increase is currently being driven by the increasing rate of the saline Mediterranean outflow that contributes to the North Atlantic Drift. The rate increase is a consequence of the increasing salinity of the Mediterranean Sea as reported by European oceanographers (Science, 279, 483–484, 1998). The rising salinity of the Mediterranean and its increasing outflow is attributed to the diversion of nearly all the in-flowing rivers for irrigation. A further substantial salinity increase should occur with the loss of all perennial polar sea ice possibly within one or two decades from 2013 if the present trend of loss continues. The trend is displayed on the University of Illinois internet site: http://arctic.atmos.uiuc.edu/cryosphere/. The increasing salinity of the Greenland Sea is now reflected in an increasing northward winter penetration by the SAC flow. According to Lamb (1972), during the early 20th century at the time of maximum extension of sea ice in April, open water normally extended only as far north as the southern cape of Spitsbergen at about 76.6° N. But in Aprils of 2013 and 2014, open water extended 380 km farther northward to the north coast of Spitsbergen. When the SAC was running strongly to replace sinking NADW in February of 2014, I observed open water extending about 730 km north from the cape into the polar ocean to latitude 83° N, where the penetration of the SAC flow was beginning to obstruct the southward flow of polar water. Even greater seasonal extensions of the SAC flow are expected with an additional Greenland Sea salinity increase after the loss of all perennial polar sea ice. This could cut off southward movement of polar water through the Fram Strait during much of the winter, and send annual pulses of the denser Atlantic water of the SAC flow into the sea north of Greenland. If these annual pulses begin to occur and allow enough denser Atlantic water to flow southward through the Nares Strait, the Baffin Bay stratification would be lost and a switch to an ice age threshold would occur. The severity of the resulting cold regional climate might have a disruptive effect on higher-latitude societies.

The paper presents research findings with 56 Roma children from Macedonia and Serbia between the ages of 3-6 years. The children’s knowledge of Romani as their mother tongue was assessed with a specially designed test. The test measures the children’s comprehension and production of different types of grammatical knowledge such as wh–questions, wh-complements, passive verbs, possessives, tense, aspect, the ability of the children to learn new nouns and new adjectives, and repetition of sentences. In addition, two pictured narratives about Theory of Mind were given to the children. The hypothesis of the authors was that knowledge of the complex grammatical categories by children will help them to understand better the Theory of Mind stories. The results show that Roma children by the age of 5 know most of the grammatical categories in their mother tongue and most of them understand Theory of Mind.
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