Log in

Relevant bibliographies by topics / Wound and wound healing activity / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Wound and wound healing activity.

Dissertations / Theses on the topic 'Wound and wound healing activity'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 dissertations / theses for your research on the topic 'Wound and wound healing activity.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Agaiby, Atif Devias. "Immune cell activity during cutaneous wound repair." Thesis, King's College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300962.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Boroumand, Soulmaz. "Investigating the epidermal Notch activation during wound healing and the consequences of prolonged Notch activity during skin wound healing." Thesis, Durham University, 2014. http://etheses.dur.ac.uk/10785/.

Full text

Abstract:

The Notch signaling pathway is critically involved in cell fate decisions during skin development and homeostasis. In the present study an in vivo model (seven-week-old male, C57BL/6) was used to elucidate the role of epidermal Notch activation in the healing of full-thickness dermal wound. Immunolocalization of activated Notch1, Notch2 and Jagged1 was performed during skin wound healing in vivo in mice. The expression level of Notch1, Notch 2 and Jagged1 in the C57BL/6 skin was examined by quantitative PCR (qPCR). This study shows that skin injury rapidly actives Notch signaling in the epider

APA, Harvard, Vancouver, ISO, and other styles

3

Adetutu, Adewale. "Evaluation of wound healing activity of selected Nigerian plants." Thesis, University of East London, 2009. http://roar.uel.ac.uk/3195/.

Full text

Abstract:

Background: Traditional medicine practitioners in Nigeria employ a range of plant preparations as wound healing agents. In spite of the use of local plants in wound healing, there is only scant literature on the wound healing components of these plants to support the continued therapeutic application of these herbal remedies. Methodology: A literature and ethnobotanical survey was conducted to determine the most widely used plants in south-western Nigeria to treat wounds. Crude extracts of the nine most widely used plants were then subjected to preliminary bioassays for fibroblast stimulation,

APA, Harvard, Vancouver, ISO, and other styles

4

Liu, Iain Xiaojun. "A study of compounds having antibacterial activity isolated from Rubus pinfaensis levl. et vant." Thesis, Robert Gordon University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385212.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Ketzner, Karissa Marie Wilson David A. "11[beta]-HSD₂ activity in an equine distal limb and thoracic wound model." Diss., Columbia, Mo. : University of Missouri-Columbia, 2009. http://hdl.handle.net/10355/6662.

Full text

Abstract:

"December 2009" The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from PDF of title page (University of Missouri--Columbia, viewed on January 5, 2010). Thesis advisor: David A. Wilson. Includes bibliographical references.

APA, Harvard, Vancouver, ISO, and other styles

6

Rayment, Erin Alexis. "Investigation into the proteolytic activity in chronic wound fluid and development of a remediation strategy." Thesis, Queensland University of Technology, 2007. https://eprints.qut.edu.au/16564/1/Erin_Alexis_Rayment_Thesis.pdf.

Full text

Abstract:

Chronic ulcers are an important and costly medical issue, causing their sufferers a large amount of pain, immobility and decreased quality of life. The common pathology in these chronic wounds is often characterised by excessive proteolytic activity, leading to the degradation of both the extracellular matrix, as well as key factors critical to the ulcer's ability to heal. As matrix metalloproteinases (MMPs), a large family of zinc-dependent endopeptidases, have been shown to have increased activity in chronic wound fluid (CWF), it was hypothesised that this specific proteolytic activity was d

APA, Harvard, Vancouver, ISO, and other styles

7

Rayment, Erin Alexis. "Investigation into the proteolytic activity in chronic wound fluid and development of a remediation strategy." Queensland University of Technology, 2007. http://eprints.qut.edu.au/16564/.

Full text

Abstract:

Chronic ulcers are an important and costly medical issue, causing their sufferers a large amount of pain, immobility and decreased quality of life. The common pathology in these chronic wounds is often characterised by excessive proteolytic activity, leading to the degradation of both the extracellular matrix, as well as key factors critical to the ulcer's ability to heal. As matrix metalloproteinases (MMPs), a large family of zinc-dependent endopeptidases, have been shown to have increased activity in chronic wound fluid (CWF), it was hypothesised that this specific proteolytic activity was d

APA, Harvard, Vancouver, ISO, and other styles

8

ROMALDINI, ALESSIO. "Platelet lysate activity in the wound-healing process: activation of endothelial and adipose tissue progenitor and differentiated cells." Doctoral thesis, Università degli studi di Genova, 2018. http://hdl.handle.net/11567/929966.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Cruise, Bethany Ann. "A NOVEL ROLE FOR ACTIVIN IN WOUND HEALING AND PSORIASIS: INDUCTION OF A SENSORY NEUROPEPTIDE." Connect to text online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=case1089320174.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Nowinski, Daniel. "Regulation of Fibroblast Activity by Keratinocytes." Doctoral thesis, Uppsala University, Department of Surgical Sciences, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5840.

Full text

Abstract:

<p>In the healing of cutaneous wounds, paracrine communication between keratinocytes and fibroblasts regulates cell differentiation, proliferation and synthesis of extracellular matrix. Deficient epidermal coverage, as seen in burn-wounds, frequently results in hypertrophic scars. Previous studies suggest that keratinocytes downregulate the production of collagen and profibrotic factors in fibroblasts. We hypothesized that keratinocytes downregulate the expression of the profibrotic factor connective tissue growth factor (CTGF) in fibroblasts, and regulate fibroblast expression of genes import

APA, Harvard, Vancouver, ISO, and other styles

11

Bridi, Henrique. "Isolamento de derivados dimétricos de floroglucinol e avaliação da capacidade proliferativa da fração lipofílica de espécies de Hypericum do Sul do Brasil." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/159640.

Full text

Abstract:

Produtos naturais são uma importante fonte de fármacos e muitos vegetais têm sido explorados na busca de substâncias potencialmente ativas. Dentre estas, destacam-se as espécies do gênero Hypericum, principalmente H. perforatum, utilizado há séculos com diversos fins terapêuticos, principalmente no tratamento de feridas. Mais recentemente, a planta está em evidência devido à comprovada atividade antidepressiva, sendo extensamente utilizada em várias partes do mundo no tratamento de depressões leve a moderada. Ambas as atividades citadas se devem a presença de derivados do floroglucinol. As esp

APA, Harvard, Vancouver, ISO, and other styles

12

Gomes, Fabiana de Souza 1982. "Topical 5-azacytidine accelerates skin wound healing in rats = Uso tópico de 5-azacitidina melhora a cicatrização de feridas cutâneas de roedores por meio do sistema ativina/folistatina." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/313600.

Full text

Abstract:

Orientador: Eliana Pereira de Araujo<br>Texto em português e inglês<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-23T05:27:47Z (GMT). No. of bitstreams: 1 Gomes_FabianadeSouza_M.pdf: 1469055 bytes, checksum: 01ebfd4043c839e80e30bebeeb9bef95 (MD5) Previous issue date: 2013<br>Resumo: O desenvolvimento de métodos que tem por objetivo acelerar e melhorar a qualidade do processo de cicatrização de feridas tem impacto positivo na condução de distúrbios de cicatrização associados a inúmeras condições médicas. Nes

APA, Harvard, Vancouver, ISO, and other styles

13

IDREES, AYESHA. "Development of 3D skin model and 3D skin infection model, as advanced testing tools for the bio-evaluation of antimicrobial biomaterials for wound healing." Doctoral thesis, Politecnico di Torino, 2019. http://hdl.handle.net/11583/2743229.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Pfalzgraff, Anja [Verfasser]. "Investigations on the activity of synthetic anti-lipopolysaccharide peptidesagainst cytoplasmic lipopolysaccharide-induced responses and their anti-inflammatory and wound healing-promoting effect in the skin / Anja Pfalzgraff." Berlin : Freie Universität Berlin, 2018. http://d-nb.info/1176708562/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Pfalzgraff, Anja [Verfasser]. "Investigations on the activity of synthetic anti-lipopolysaccharide peptides against cytoplasmic lipopolysaccharide-induced responses and their anti-inflammatory and wound healing-promoting effect in the skin / Anja Pfalzgraff." Berlin : Freie Universität Berlin, 2018. http://d-nb.info/1159900647/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Errington, Rachel J. "In vitro wound healing." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357419.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Underdown, Mary Jane. "Antioxidants and Wound Healing." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/honors/65.

Full text

Abstract:

Neutrophils and cytokines present during an inflammatory response produce oxidants, such as reactive oxygen species (ROS) or reactive nitrogen species (RNS). These oxidants act as free radicals, a highly reactive species that steal electrons from nearby molecules to satisfy their valence electron needs. The removal of electrons by free radicals produces damage within the healthy cells of tissue. Antioxidants can be used to reduce this oxidative stress and reestablish the necessary environment for wound healing by donating electrons to the free radicals, sparing the damaging effects oxidatio

APA, Harvard, Vancouver, ISO, and other styles

18

Cook, Julian. "Mathematical models for dermal wound healing : wound contraction and scar formation /." Thesis, Connect to this title online; UW restricted, 1995. http://hdl.handle.net/1773/6756.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Head, Cynthia C. "Hormonal regulation of cutaneous wound healing effect of androstenediol on stress-impaired wound healing /." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1186957947.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Sherratt, Jonathan Adam. "Mathematical models of wound healing." Thesis, University of Oxford, 1991. https://ora.ox.ac.uk/objects/uuid:4e3ea7dd-33c6-4696-a2ec-aa3499c8b3f6.

Full text

Abstract:

The complex mechanisms responsible for mammalian wound healing raise many biological questions that are amenable to theoretical investigation. In the first part of this thesis, we consider the role of mitotic auto-regulation in adult epidermal wound healing. We develop a reaction-diffusion model for the healing process, with parameter values based on biological data. The model solutions compare well with experimental results on the normal healing of circular wounds, and we analyse the solutions in one spatial dimension as travelling waves. We then use the model to perform 'mathematical experim

APA, Harvard, Vancouver, ISO, and other styles

21

Loots, Miriam Alfonsa Maria. "Wound healing in diabetic ulcers." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2002. http://dare.uva.nl/document/66897.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

McCluskey, Jane T. "Mechanisms of embryonic wound healing." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318851.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Bailey, Matthew John. "Protein changes in wound healing." Thesis, King's College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427693.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Rippon, Mark Geoffrey. "The physiology of wound healing." Thesis, Manchester Metropolitan University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240980.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

McHugh, Jolene. "Sensors for monitoring wound healing." Thesis, Ulster University, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686440.

Full text

Abstract:

Early identification of infection is imperative in the management of chronic wounds in preventing limb threatening events. There is a clear requirement for the development of in situ sensors that can monitor the healing progress of chronic wounds and identify the early onset of infection, providing the clinician with a more detailed picture of the wound dynamics. A variety of carbon composite materials were employed for use in wound monitoring technologies. The mechanical flexibility of the polyethylene and polycarbonate films are ideal for incorporation within existing dressing materials and

APA, Harvard, Vancouver, ISO, and other styles

26

Ramier, James Charles. "Biomechanics of corneal wound healing /." Online version of thesis, 1992. http://hdl.handle.net/1850/10786.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Walters, Kyle D. "Wound healing in Caribbean sponges /." Electronic version (PDF), 2003. http://dl.uncw.edu/etd/2003/waltersk/kylewalters.html.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Kanapathy, M. "Translational studies in wound healing." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1569432/.

Full text

Abstract:

This work explores the role of gap junctional proteins (GJP) in wound healing in two clinical settings: venous disease and epidermal grafting. Chronic wounds and ulcers are common and a feared problem particularly in the elderly, causing pain and disability. Treatment costs are estimated at £2-3 billion to the NHS with a further loss of 2 million workdays per year. Varicose veins are the major contributor to the prevalence of ulcers affecting about 0.3-0.5% of the population at any point of time. The expression of GPJ; connexins 43, 30 and 26 were explored in a cross-sectional study of patient

APA, Harvard, Vancouver, ISO, and other styles

29

Pawar, Harshavardhan Vilasrao. "Development and characterisation of medicated wound dressings for chronic wound healing." Thesis, University of Greenwich, 2013. http://gala.gre.ac.uk/11952/.

Full text

Abstract:

Chronic wounds are difficult to heal and exhibit physiological features including prolonged inflammatory phase, mixed bacterial flora resistance and formation of biofilms, ineffectiveness of topical antimicrobials and high volumes of wound exudate. Polymeric gels of Polyox (POL) and blends of POL with carrageenan (CAR), chitosan (CS), hydroxypropylmethylcellulose (HPMC) and sodium alginate (SA) in different weight ratios were used to prepare films by the solvent casting technique and evaluated using scanning electron microscopy (SEM), X-ray powder diffraction (XRPD), differential scanning calo

APA, Harvard, Vancouver, ISO, and other styles

30

Hsu, Chiao-Wen Ivy. "Serpina3n accelerates wound closure in a murine model of diabetic wound healing." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/50361.

Full text

Abstract:

Chronic, non-healing wounds are a major complication of diabetes and are characterized by chronic inflammation and excessive protease activity. While once thought to function primarily as a pro-apoptotic serine protease, granzyme B (GzmB) can also accumulate in the extracellular matrix during chronic inflammation and cleave extracellular matrix (ECM) proteins that are essential for proper wound healing, including fibronectin. We hypothesized that GzmB contributes to the pathogenesis of impaired diabetic wound healing through excessive degradation of the ECM. In the first part of the thesis, we

APA, Harvard, Vancouver, ISO, and other styles

31

Gan, Lisha. "Corneal cellular proliferation and wound healing /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4505-5/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Giannelis, Georgios. "Matrix metalloproteinases in scarless wound healing." Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/36241.

Full text

Abstract:

Objectives: Wound healing in skin often results in scar formation, whereas wound healing in oral palatal mucosa is fast and rarely results in scarring. Understanding the mechanisms that promote oral scarless wound healing may provide novel approaches to prevent scar formation in skin. The goal of the study was to compare the abundance of the major collagenases MMP-1 and MMP-13 and gelatinases MMP-2 and MMP-9 in normal unwounded oral mucosa and skin and in experimental excisional wounds in skin (healing results to scar formation) and oral mucosa (wounds heal with minimal scar formation) at vari

APA, Harvard, Vancouver, ISO, and other styles

33

LeBlanc, Sarah. "CEACAM1 deficiency delays cutaneous wound healing." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=66794.

Full text

Abstract:

CEACAM1 (CarcinoEmbryonic Antigen-related Cell Adhesion Molecule 1), is expressed at the surface of new blood vessels of tissues undergoing proliferation. In human tumors, CEACAM1 expression is associated with early stages of angiogenesis. CEACAM1 is a known pro-angiogenic factor, increasing VEGF activity in vivo; however, the role of CEACAM1 in angiogenesis warrants further investigation. Excisional wounds were used as an experimental model, as many of the processes that occur in healing wounds also take place in tumor growth - epithelial hyperproliferation, inflammation, an

APA, Harvard, Vancouver, ISO, and other styles

34

Liao, Laura. "Signalling in single cell wound healing." Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/44784.

Full text

Abstract:

A single cell, such as a frog egg, is able to repair injuries by orchestrating a localized signalling response on the plasma membrane. Proteins called Rho GTPases are recruited to, and form patterns around, the wound site. Patterning allows testable hypotheses to be made about the structure of the signalling network. Here, we extend a Rho GTPase signalling model from Simon et al. (2013) to test how a family of enzymes, protein kinase C (PKC), plays a role in cell repair signalling. Our models let PKCs affect basal Rho GTPase activation and/or inactivation rates, with increasing spatial detail.

APA, Harvard, Vancouver, ISO, and other styles

35

Waugh, Helen Victoria. "Mathematical models of diabetic wound healing." Thesis, Heriot-Watt University, 2007. http://hdl.handle.net/10399/99.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Bannon, Pauline. "Activation of macrophages during wound healing." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/activation-of-macrophages-during-wound-healing(28ce7af3-3516-43ed-b0e0-93995691e1ac).html.

Full text

Abstract:

Wound repair is a complex series of events that begins immediately after wounding, and can continue for a number of months to years. Various physiological and mechanical factors may impair the healing response, resulting in a chronic wound, characterised by a sustained inflammatory response. One of the main cells involved in both the inflammatory phase and proliferation phase of wound healing is the macrophage. There are thought to be different activation states which allow the macrophage to be involved in the two different phases of wound healing, namely the classically activated macrophage a

APA, Harvard, Vancouver, ISO, and other styles

37

Westgate, Samantha Jane. "Biofilms and chronic equine wound healing." Thesis, University of Liverpool, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569171.

Full text

Abstract:

Biofilms in human wounds are considered responsible for the non-healing nature of some chronic wounds. Recent advancements in chronic wound healing have resulted from an increased understanding and awareness of biofilms. These findings led to the hypothesis that bacterial biofilms were also present within the wound bed of non- healing equine wounds and could be responsible for the unexplained retardation of some chronic equine wounds. This study aimed to collect and present information regarding the microbiological composition of equine wounds and to present evidence supporting the presence of

APA, Harvard, Vancouver, ISO, and other styles

38

Flegg, Jennifer Anne. "Mathematical modelling of chronic wound healing." Thesis, Queensland University of Technology, 2009. https://eprints.qut.edu.au/40164/1/Jennifer_Flegg_Thesis.pdf.

Full text

Abstract:

Chronicwounds fail to proceed through an orderly process to produce anatomic and functional integrity and are a significant socioeconomic problem. There is much debate about the best way to treat these wounds. In this thesis we review earlier mathematical models of angiogenesis and wound healing. Many of these models assume a chemotactic response of endothelial cells, the primary cell type involved in angiogenesis. Modelling this chemotactic response leads to a system of advection-dominated partial differential equations and we review numerical methods to solve these equations and argue that t

APA, Harvard, Vancouver, ISO, and other styles

39

Hong, Sung-Ha. "Development of a wound dressing for detection of bacteria with wound healing properties." Thesis, University of Bath, 2013. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.619143.

Full text

Abstract:

There has been a significant increase in children’s burns in the past several years and figures indicate that children suffer more burns compared to any other age groups. The main concern following a burn is the possibility of infections. The aim of this project is to construct a unique wound dressing, which enhances healing and stimulates wound closure by incorporation of collagen, as well as signalling the presence of pathogenic bacteria on colonisation. The process of signalling bacterial colonisation was achieved by incorporation of a phospholipid based nanocapsule, with a colourimetric re

APA, Harvard, Vancouver, ISO, and other styles

40

Khathide, Bongai. "Assessing modified chitosan wound dressings to enhance wound healing in the porcine model." Thesis, University of Pretoria, 2020. http://hdl.handle.net/2263/75685.

Full text

Abstract:

Dressings enhancing wound healing can improve the outcome of wounds where tissue replacement is required, like for burns and ulcers. Treatment of these wounds is complex due to their depth and excessive tissue loss. Replacement of the lost tissue and delivery of growth factors could enhance healing and reduce scarring. The natural biomaterial; chitosan is reported to bind growth factors, with reduced wound healing times when used in dressings. This study aimed to modify chitosan into a wound dressing filler that would optimise growth factor delivery to full-thickness wounds and overall reduce

APA, Harvard, Vancouver, ISO, and other styles

41

Santhanam, Ramya. "LOCALIZED WOUND HEALING: A MATHEMATICAL MODEL FOR ELECTROMAGNETIC INDUCTION ON COATED NANOFIBER WOUND DRESSINGS." Akron, OH : University of Akron, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=akron1147883471.

Full text

Abstract:

Thesis (M.S.)--University of Akron, Dept. of Biomedical Engineering, 2006.<br>"May, 2006." Title from electronic thesis title page (viewed 12/03/2007) Advisor, S.I. Hariharan; Committee members, Daniel B. Sheffer, Narender P. Reddy; Department Chair, Daniel B. Sheffer; Dean of the College, George K. Haritos; Dean of the Graduate School, George R. Newkome. Includes bibliographical references.

APA, Harvard, Vancouver, ISO, and other styles

42

Jacobsson, Lena. "Evaluation of Novel Materials for Wound Healing." Thesis, Linköping University, Department of Physics, Chemistry and Biology, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-16592.

Full text

Abstract:

<p>Rapid wound healing is important to regain the skins protective function after injury. Studies have shown that enamel matrix proteins (EMP) have many desirable effects which may accelerate wound healing [Bosshardt <em>et al.</em> 2008].</p><p> </p><p>Polymers (Polymer A, B and C) were formed into a mat form, with or without incorporated enamel matrix derivative (EMD) (Collaboration partner). The materials may be suitable for wound care and drug delivery systems.</p><p> </p><p>Protein release tests were performed on samples incubated in physiological-like solution using pyrogallol red staini

APA, Harvard, Vancouver, ISO, and other styles

43

Koskela, M. (Marjo). "Wound healing and skin in severe sepsis." Doctoral thesis, Oulun yliopisto, 2016. http://urn.fi/urn:isbn:9789526214269.

Full text

Abstract:

Abstract It is a generally accepted dogma that sepsis disturbs skin function and wound healing, but surprisingly there is only remote pathophysiological evidence available behind that presumption. As the skin is the largest defensive barrier, the skin dysfunction in severe sepsis deserves more attention. In this study, the suction blister model was used to create experimental wounds. The study population included 44 patients with severe sepsis and 15 controls. The blister fluid was collected to analyse cytokine profile of the skin. The transepidermal water loss and blood flow from the wound we

APA, Harvard, Vancouver, ISO, and other styles

44

Szpalski, Caroline. "Co-morbidities induced vasculogenic impaired wound healing." Doctoral thesis, Universite Libre de Bruxelles, 2013. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209533.

Full text

Abstract:

A. Background<p><p>Skin wound healing (WH) is a dynamic and extremely determinate process of cellular, humoral and molecular mechanisms which begins directly after wounding and can last for years. WH is described as is an intricate process in which the skin (or another organ-tissue) repairs itself after injury. The process of skin WH occurs through the actions of an interplay of cells, growth factors and cytokines leading to wound closure.<p><p>WH occurs in three precisely and highly programmed phases: the inflammatory phase (day 0 to day 7) followed by the proliferative phase or vasculogenic

APA, Harvard, Vancouver, ISO, and other styles

45

Atherton, Paul. "The role of ultrasound in wound healing." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/the-role-of-ultrasound-in-wound-healing(94a0808e-f676-4431-a415-582525f24674).html.

Full text

Abstract:

Low Intensity Pulsed Ultrasound (LIPUS) is used clinically to promote wound healing. In vivo studies show that LIPUS is effective in a wide range of tissue types, and in vitro experiments show that multiple cell types respond to LIPUS stimulation. Despite this, there is no unifying mechanism of how LIPUS stimulation is sensed by cells, and it is unknown what the early signalling events are. The LIPUS signal is a mechanical one; therefore I hypothesised that mechanosensitive organelles, called focal adhesions, would be essential for the induction of cellular signalling events in response to thi

APA, Harvard, Vancouver, ISO, and other styles

46

Pugazhenthi, Kamali, and n/a. "Melatonin : a new factor in wound healing." University of Otago. Department of Pharmacology & Toxicology, 2008. http://adt.otago.ac.nz./public/adt-NZDU20081208.151313.

Full text

Abstract:

Wound healing is a dynamic process that ultimately leads to restoration of tissue integrity and function. The pineal gland hormone melatonin is known for its anti-oncotic, anti- inflammatory and immuno-modulatory effects. However, its role in wound healing has not been established. Since melatonin is synthesised endogenously, we primarily sought to investigate whether the melatonin receptors played a role in the wound healing process. Using immunohistochemical methods and Western blot analysis we observed that MT₁ was normally absent in the rat skin but was strongly expressed on day 1 to day

APA, Harvard, Vancouver, ISO, and other styles

47

Tomás, Barberán Santiago. "Inflammation and wound healing following photorefractive keratectomy /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3449-5/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Lai, Amy M. "Role of aminopeptidase N in wound healing." Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/39957.

Full text

Abstract:

The dynamics and complexity of tissue repair are dominated by specific and intricately coordinated cellular events. Disruptions at the level of cellular communication are associated with imbalanced extracellular matrix (ECM) synthesis/degradation leading to fibrosis and chronic wounds. Our group has demonstrated that 14-3-3 sigma (also known as stratifin) functions as a stimulator of matrix metalloproteinase-1 (MMP-1) through interactions with aminopeptidase N (APN) on the surface of dermal fibroblasts. In this doctoral research project, it is hypothesized that APN functions as a receptor for

APA, Harvard, Vancouver, ISO, and other styles

49

Zhang, Gaofeng. "Electric signals regulated immunomodulation and wound healing." Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/42430/.

Full text

Abstract:

Endogenous electric fields (EFs) are present during a variety of physiologic and pathologic events, including penetrating injury to epithelial barriers. An applied electric field with strength within the physiologic range can induce directional cell migration of epithelial cells, endothelial cells, fibroblasts, and immune cells suggesting a potential role in controlling cell behaviours during wound healing. Dendritic cells (DCs) and dermal fibroblasts were used to explore the molecular mechanisms underlie EF-induced cell activities during two aspects of wound healing: immune response and remod

APA, Harvard, Vancouver, ISO, and other styles

50

Sharma, G. U. "Modulation of wound healing after glaucoma surgery." Thesis, University College London (University of London), 2016. http://discovery.ucl.ac.uk/1527404/.

Full text

Abstract:

Glaucoma is the leading cause of irreversible blindness worldwide. Glaucoma is a progressive eye disorder characterised by atrophy of the optic nerve. In some cases, poor aqueous drainage may cause raised intraocular pressure, which causes damage to the optic nerve, leading to blindness. One of the approaches to lower intraocular pressure is to surgically create a drainage channel for the outflow of aqueous humour. Impaired wound healing and continued scarring response at the site of surgery can lead to suboptimal intraocular pressure control and eventual failure of surgery in many patients. C

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!