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Journal articles on the topic 'Wound and wound healing activity'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Pandurangan, Perumal. "Review on Wound Healing Activity." International Journal of Pharmacognosy & Chinese Medicine 6, no. 1 (2022): 1–8. http://dx.doi.org/10.23880/ipcm-16000224.

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Background: Wound healing is considered to be the beneficial cellular and biological components that divide the scale in an effort to improve wound healing. Wound healing is defined as physiological phase and delayed wound healing will increase the risk of microorganism infection. Improved wound healing is done by reducing the time required for healing or to reduce the risk of miscarriage. Purpose: The World Health Organization (WHO), along with India, has promoted the use of traditional medicine because it is inexpensive, readily available, and widely believed in the community in developing c

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V. Subhaa, V. Subhaa, Dr D. Sukumarb Dr. D. Sukumarb, and Dr V. Elangoc Dr. V. Elangoc. "Wound healing activity of Cestrum elegans." Indian Journal of Applied Research 1, no. 9 (2011): 5–6. http://dx.doi.org/10.15373/2249555x/jun2012/3.

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Krunal, Sameja, and Rao Shaival. "Evaluation of In Vivo Wound Healing Activity of Cassia Tora Leaf Extract." International Journal of Toxicological and Pharmacological Research 9, no. 4 (2017): 212–15. https://doi.org/10.5281/zenodo.12697459.

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Plant Cassia tora also known as Chakra Marda or Puvad was found in most part of India and it was previously used in treatment of common skin ailments by Indian tribes. However, there are no scientific evidences justifying use of Cassia tora in wound healing. Therefore, the present study was performed to evaluate wound healing activity of Cassia tora leaf methanolic extract.  These activities were studied by two animal models i.e. Excision wound model and incision wound model in Wistar rats. In excision wound model compared to the control group, percentage contraction was significantly hig

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Revathi, D.* and Rajeswari M**. "WOUND HEALING ACTIVITY OF GUETTARDA SPECIOSA LINN." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 08 (2018): 7896–903. https://doi.org/10.5281/zenodo.1402711.

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<em>Traditionally the plant diversity was conserved through the temple premises based on their medicinal values. Medicinal activities of many temple plants are scientifically unexplored. The present research was focused to evaluate the wound healing activity of the sacred tree Guettarda speciosa commonly known as Indian lavender which is conserved in many temples and also promoted to grown as ornamental. The plant leaf is enriched with alkaloids, flavonoids, phenols, tannins, terpenoids, etc. Traditionally the leaf is used in cuts and wounds. Hence, the present research carried out to find the

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Wallace, Laura A., Lauren Gwynne, and Tobias Jenkins. "Challenges and opportunities of pH in chronic wounds." Therapeutic Delivery 10, no. 11 (2019): 719–35. http://dx.doi.org/10.4155/tde-2019-0066.

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Regarded as a silent epidemic, chronic wounds are a global public health issue. Wound healing is a complex, synchronized cascade of physiological processes restoring the anatomic and functional integrity of the skin; however, chronic wounds fail to proceed through the wound healing cascade. Wound pH oscillates during wound healing, usually traversing from a neutral pH to an acidic pH, while chronic wounds perpetuate in an elevated alkaline milieu. Although a neglected clinical parameter, pH has implications for relatively all pathologies of wound healing affecting oxygen release, angiogenesis,

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Bhopale, Raman S., Rajesh D. Jangam, Harshada M. Dhekale, Prachi P. Aiwale, Vitthal J. Chaware, and Vivekkumar K. Redasani. "A Detailed Review on Diabetic Wound Healing Activity." Asian Journal of Pharmaceutical Research and Development 11, no. 4 (2023): 95–105. http://dx.doi.org/10.22270/ajprd.v11i4.1293.

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Skin damage is known as a wound. Hemostasis, inflammatory, proliferative, and tissue remodelling or resolution are the four perfectly timed and highly planned phases that make up the normal biological process of wound healing in the human body. There are two basic categories of wounds: acute wounds and chronic wounds. Long-term negative effects on one's health are caused by the chronic metabolic condition known as diabetes mellitus, which is becoming more common. 25 percent of those with diabetes mellitus are thought to have poor wound healing due to their diabetes. Oxygenation, infection, hor

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Mohammad, Asif, and Nanda Sharma Jyoti. "An Overview of Medicinal Plants Possessing Wound Healing Activity: A Natural Effective Wound Healer." Research and Review Drugs and Drugs Development 1, no. 2 (2019): 43–60. https://doi.org/10.5281/zenodo.3248513.

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<em>Wounds are the disruption of anatomical and efficient integrity of living tissue. Wound healing is a complicated and frequent cascade of events, with a range of cellular and biochemical procedures, eventually resulting in the rebuilding and revival of damaged tissue. Several herbs and medicinal plants proved to be a wound healer and formulated for treatment of wounds. Plants and their extracts have vast potential for the treatment of wounds. The phytomedicines for wound healing are not only cheap and affordable but are also safe as hyper sensitive reactions are rarely encountered with the

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Manjunatha, BK, SM Vidya, V. Krishna, and KL Mankani. "Wound healing activity ofLeucas hirta." Indian Journal of Pharmaceutical Sciences 68, no. 3 (2006): 380. http://dx.doi.org/10.4103/0250-474x.26681.

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Reddy, BMadhava, B. Krishnaveni, V. Neeharika, S. Venkatesh, and R. Padmavathy. "Wound healing activity ofCarallia brachiatabark." Indian Journal of Pharmaceutical Sciences 71, no. 5 (2009): 576. http://dx.doi.org/10.4103/0250-474x.58184.

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10

AGREN, M. S. "Gelatinase activity during wound healing." British Journal of Dermatology 131, no. 5 (1994): 634–40. http://dx.doi.org/10.1111/j.1365-2133.1994.tb04974.x.

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11

Margaret, I., Reddy P. Srinivasa, B. Praveen, and Jamil Kaiser. "Wound healing activity ofGliricidia maculata." Phytotherapy Research 12, no. 8 (1998): 586–88. http://dx.doi.org/10.1002/(sici)1099-1573(199812)12:8<586::aid-ptr376>3.0.co;2-r.

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12

Vasanthalaxmi K, Vasanthalaxmi K., Saraswathi Udupa, and Laximinarayana Udupa. "Wound Healing Activity of Ten Indigenous Plants in Incision and Excision Wound Models in Albino Rats." International Journal of Scientific Research 2, no. 9 (2012): 56–58. http://dx.doi.org/10.15373/22778179/sep2013/164.

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13

Kasouni, Athanasia I., Theodoros G. Chatzimitakos, Constantine D. Stalikas, Theoni Trangas, Alexandra Papoudou-Bai, and Anastassios N. Troganis. "The Unexplored Wound Healing Activity of Urtica dioica L. Extract: An In Vitro and In Vivo Study." Molecules 26, no. 20 (2021): 6248. http://dx.doi.org/10.3390/molecules26206248.

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Wound healing is a great challenge in many health conditions, especially in non-healing conditions. The search for new wound healing agents continues unabated, as the use of growth factors is accompanied by several limitations. Medicinal plants have been used for a long time in would healing, despite the lack of scientific evidence veryfying their efficacy. Up to now, the number of reports about medicinal plants with wound healing properties is limited. Urtica dioica L. is a well-known plant, widely used in many applications. Reports regarding its wound healing potential are scant and sparse.

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Takahashi, Makoto, Yousuke Morimoto, Miyuki Kon, and Kenji Saga. "A Histological Study of Cutaneous Thermal Wounds Using aClostridium perfringens-Derived Wound Healing Substance with Wound Healing Stimulation Activity." Journal of Dermatology 22, no. 2 (1995): 98–106. http://dx.doi.org/10.1111/j.1346-8138.1995.tb03351.x.

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15

Beg, Mohd Riyaz, Shital Ghodinde, and Vidhi Gupta. "Plant mediated green synthesis of Zinc Oxide Nanoparticles for burn wound therapy." International Journal of Advance Research 8, no. 7 (2020): 521–47. https://doi.org/10.5281/zenodo.3986806.

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In this changing world, we all are surrounded by the surmountable risk of getting injured. Amongst various risk factors, major burns are the most distressing and catastrophic. Burn wounds are not easy to heal via natural healing process and ultimately ended up with scar formation. If the degree of burn is high then the loss of tissue and its function is very common. To fasten-up the natural burn wound healing; zinc, an essential trace element is found to be very much effective. But due to its’ particle size limitation, less contact with wounded cells and tissues, and high inherent toxici

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Geetha, Rani Valaparla* Tejaswini K. Divya Vani P. Sirisha K. Srikanth K. Manoj Kumar K. "A STUDY ON SYNERGESTIC WOUND HEALING ACTIVITY OF CAPSICUM AND PIGEON PEA." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 02 (2018): 1233–36. https://doi.org/10.5281/zenodo.1190309.

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A study to investigate the use of aqueous extracts of poly herbs in promoting wound healing on experimentally induced open wound in albino rats was conducted. The wound healing activity of aqueous extract of the leaves from Cajanus cajan (AECc) and Capsicum annum (AECa), was evaluated by the rats of healing by wound concentration and period of epithelization at different days post- wound using the wound excision model. On day 9th, the mixture of AECc and AECa –treated animals exhibited significative reduction in the wound area than individual plant extracts when compared with standard dr

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Ambika, Anitha P., and Sreesha N. Nair. "Wound Healing Activity of Plants from the Convolvulaceae Family." Advances in Wound Care 8, no. 1 (2019): 28–37. http://dx.doi.org/10.1089/wound.2017.0781.

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18

Firda, Rahmania, and Fawzy Ahmad. "Efficacy of Honey-Based Wound Dressing Versus Hydrogel-Based Wound Dressing in Wound Healing Process: A Literature Review." INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES 04, no. 05 (2024): 812–17. https://doi.org/10.5281/zenodo.11125857.

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<strong>Introduction:</strong> Wound dressing is a fundamental aspect of modern healthcare, encompassing a diverse range of materials and techniques aimed at optimizing the healing process while safeguarding against infection and further injury. By understanding the specific benefits of different types of wound dressings, healthcare professionals can optimize the healing process and improve patient outcomes   <strong>Methods:</strong> This literature review was compiled using information from various open access online databases. Data were collected and analyzed.   <strong>

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Borsaikia, Ansumita, Saikat Sen, Pal Gogoi, and Biplab Kumar Dev. "SURVEY OF ETHNO MEDICINAL PLANT SHOWING WOUND HEALING ACTIVITY." International Journal of Advanced Research 9, no. 08 (2021): 1142–59. http://dx.doi.org/10.21474/ijar01/13364.

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In most recent couple of a few years, there has been a unprecedented advancement in understanding the biochemical and cell occasions of typical injury recuperating or wound healing. Healing is survival mechanism and represents a trial to take care of normal complex body part and performance.Wound healing could be a process by which tissue regeneration occurs. Healing of wounds, either accidental or surgical interventions, involves complex activities of blood cells, tissues, soluble mediators, cytokines and several other growth factors. This increased cellular activity of damaged tissue enhance

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Jain, V., V. Prasad ., and R. S. Pandey . "Wound Healing Activity of Desmodium gangeticum in Different Wound Models." Journal of Plant Sciences 1, no. 3 (2006): 247–53. http://dx.doi.org/10.3923/jps.2006.247.253.

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"Wound Healing Activity of Desmodium gangeticum in Different Wound Models*." Journal of Plant Sciences 5, no. 3 (2010): 328–34. http://dx.doi.org/10.3923/jps.2010.328.334.

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22

Hoskins, Robert D., Erin E. Sutton, Deborah Kinor, Julia M. Schaeffer, and Stefania Fatone. "Using vacuum-assisted suspension to manage residual limb wounds in persons with transtibial amputation: A case series." Prosthetics and Orthotics International 38, no. 1 (2013): 68–74. http://dx.doi.org/10.1177/0309364613487547.

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Background: Persons with amputation and residual limb wounds would benefit from the ability to continue wearing a prosthesis while healing. Sockets with vacuum-assisted suspension may reduce intra-socket motion and be less disruptive to wound healing. The purpose of this case series was to measure residual limb wound size over time in persons with transtibial amputation while using prostheses with vacuum-assisted suspension. Case description and methods: Six subjects with residual limb wounds were fit with vacuum-assisted suspension sockets. Wound surface area was calculated using ImageJ softw

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Rayner, Timothy E., Allison J. Cowin, J. Gray Robertson, et al. "Mitogenic whey extract stimulates wound repair activity in vitro and promotes healing of rat incisional wounds." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 278, no. 6 (2000): R1651—R1660. http://dx.doi.org/10.1152/ajpregu.2000.278.6.r1651.

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The ability of single growth factors to promote healing of normal and compromised wounds has been well described, but wound healing is a process requiring the coordinated action of multiple growth factors. Only the synergistic effect on wound healing of combinations containing at most two individual growth factors has been reported. We sought to assess the ability of a novel milk-derived growth factor-enriched preparation [mitogenic bovine whey extract (MBWE)], which contains six known growth factors, to promote repair processes in organotypic in vitro models and incisional wounds in vivo. MBW

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Wafi, Viky Hibatu, Yudhy Arius, Ivan Joalsen Mangara Tua, Swandari Paramita, and Endang Sawitri. "The Wound Healing Potential of Honey and Propolis from Stingless Bees in Acute Wounds." MAHESA : Malahayati Health Student Journal 5, no. 7 (2025): 3153–64. https://doi.org/10.33024/mahesa.v5i7.18933.

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ABSTRACT Honey and propolis from stingless bees have been reported to promote wound healing due to their anti-inflammatory, antioxidant, antibacterial, and moisturizing activities. However, variations in compounds and biological activities of these products can arise due to geographical and bee origin differences. This study aimed to investigate the wound healing potential of stingless bee honey and propolis from East Kalimantan in an acute wound animal model. Honey and propolis from stingless bees have been reported to promote wound healing due to its anti-inflammatory, antioxidant, antibacte

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Angelina, T. Gonzales. "Assessment of the crude ethanol leaf extracts of Momordica charantia Linn., Moringa oleifera Lam., Tabernaemontana pandacaqui Poir. and Mollugo oppositifolia Linn. for its wound healing activity in castrated piglets." International Journal of Biosciences (IJB) 24, no. 1 (2024): 166–78. https://doi.org/10.5281/zenodo.11114873.

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Botanicals possess healing and medicinal properties which could be an alternative to synthetic therapeutic drugs. The study evaluated the healing activity of selected botanicals on castration wounds of piglets. Crude ethanol leaf extracts of selected botanicals were subjected to wound healing activity assessment. Wound surface area, photography of wounds, epithelialization and scar appearance were assessed.  Results showed that all plants contain reducing sugars, tannins, carbohydrates, polyphenols, and flavonoids which may have contributed to wound healing activity independently or syner

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Shivananjappa, Mahesh, Meghana H D, Manasa R, Santosha D U, and Shekhara Naik R. "Wound healing activity of Centella Asiatica." IP Journal of Nutrition, Metabolism and Health Science 6, no. 1 (2023): 1–6. http://dx.doi.org/10.18231/j.ijnmhs.2023.001.

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is a medicinal herb in family Commonly known as Brahmi, Gotu kola, Ondelaga, Indian pennywort and found in swampy areas and temperate regions. It has many pharmacological properties like anticancer, antidiabetic, immunity booster, memory enhancer, wound healing, anticancer, neuroprotective. All extracts of facilitate the wound healingprocess in both incision and burn wounds by inhibiting inflammation, inducing collagen synthesis, inducing vasodilation and promoting angiogenesisThis review aimed to explore the wound healing activity of , the botanical description, phytochemistry, traditional us

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Zihayat, Bahare, Arash Khodadadi, Molook Torabi, Mohammad Mehdipour, Mohsen Basiri, and Majid Asadi-Shekarri. "WOUND HEALING ACTIVITY OF SHEEP’S BLADDER EXTRACELLULAR MATRIX IN DIABETIC RATS." Biomedical Engineering: Applications, Basis and Communications 30, no. 02 (2018): 1850015. http://dx.doi.org/10.4015/s1016237218500151.

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Diabetic ulcers (DUs) are a chronic, non-healing diabetes complication that leads to high hospital expenses and, in extreme cases, to amputation. Peripheral vascular diseases, diabetic neuropathy, abnormal cellular and cytokine activity are among the major factors that hinder diabetic wound healing. DUs represent an important challenge in the development of new and efficient wound dressings. The extracellular matrix (ECM) has been effectively used as a scaffold for constructive remodeling of multiple tissues in animal and human. Sheep’s urinary bladder matrix was evaluated for its wound healin

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Zunnita, Oktaviana, Moerfiah, and Rinal Apriana. "The Potential Activity of Kecombrang (Etlingera elatior) Leaf, Flower, and Stem Extracts on the Duration of Wound Healing in Mice (Mus musculus)." FITOFARMAKA: JURNAL ILMIAH FARMASI 14, no. 1 (2024): 59–67. http://dx.doi.org/10.33751/jf.v14i1.10046.

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Wound is skin tissue damage due to trauma from a sharp object. Kecombrang flower extract is known to be effective in speeding up the healing of wounds because it contains flavonoids, saponins, tannins and steroids. The leaves and stems also contain these compounds, so this research was conducted to see the difference in the potential activity of the wound healing process of the kecombrang plant on the time of wound healing. Natural ingredient extracts are wound healing agents that can fight infection and speed up wound healing. This study used 5 treatment groups consisting of control (-) disti

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Sneha, A. Vikhe Abhishek R. Putale Prashant M. Rane Rohit D. Nagare Aman S. Pinjari. "Formulation Development & Evaluation Of Herbal Cream For Wound Healing Activity." International Journal in Pharmaceutical Sciences 2, no. 5 (2024): 610–15. https://doi.org/10.5281/zenodo.11186336.

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This study focuses on the development and evaluation of a novel wound healing cream aimed at promoting efficient wound repair and tissue regeneration. The cream formulation includes key ingredients known for their therapeutic properties, including anti-inflammatory, antimicrobial, and skin regeneration-promoting agents. Preliminary results indicate that the wound healing cream exhibits promising properties, including significant antimicrobial activity, enhanced cell migration and proliferation, reduced inflammation, and accelerated wound closure rates compared to control groups. Histological a

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Nwajiobi, F. O., C. O. Anyamene, and C. C. Abana. "Effects of Bacteriocin Extracted from Lactobacillus rhamnosus on Cutaneous Wound Healing in Mice." Journal of Advances in Microbiology 23, no. 7 (2023): 15–25. http://dx.doi.org/10.9734/jamb/2023/v23i7734.

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Aim: This study evaluates the effects of bacteriocin produced by Lactobacillus rhamnosus on cutaneous wound healing in mice. Study Design: Randomized experimental design was employed in the study. Methodology: Probiotic L. rhamnosus was isolated from nono milk using MRS agar media and identified based on morphological and biochemical characteristics. The potent bacterium was subjected to bacteriocin production. Antimicrobial activity of the bacteriocin was carried out against wound pathogenic bacteria and wound healing effects of the bacteriocins were assessed on mice. 2 mm cutaneo

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Hakim, Antoine, Wassim Abdel Wahed, and Ream Nayal. "Evaluation of Wound Healing Activity of Schinus Molle Fruits Essential Oil in Rats." International Journal of Pharmaceutical Sciences and Nanotechnology 9, no. 5 (2016): 3502–5. http://dx.doi.org/10.37285/ijpsn.2016.9.5.8.

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 Wounds are injuries that break the skin or other body tissues. They often happen because of an accident or surgery. They include cuts, scrapes, scratches, and punctured skin. Herbal extracts and essential oils have been used since ancient civilizations to treat wounds. Schinus molle L. (Anacardiaceae) is an aromatic tree originated from South America but now it is cultivated in Mediterranean area. The plant was used in folk medicine as a vulnarary. However there is no scientific evidence regarding its use in wound healing, therefore the aim of the present study was to evaluate the wound

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Fullana, F., L. Grande, J. Fernadez-Llamazares, V. González-Mestre, and J. A. Salvá. "Skin Prolylhydroxylase Activity and Wound Healing." European Surgical Research 25, no. 6 (1993): 370–75. http://dx.doi.org/10.1159/000129303.

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Daminola, A.U.F., A.S. Eboh, R.S. Ogbomade, et al. "Wound Healing Activity of Extract of Emilia sonchifolia." Pharmaceutical and Chemical Journal 7, no. 3 (2020): 1–4. https://doi.org/10.5281/zenodo.13954372.

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In traditional medicine <em>Emilia sonchifolia</em> is widely used for the treatment of various ailments including ulcer and wound healing. The phytochemical screening of <em>Emilia sonchifolia</em> indicates the presence of biologically active ingredients in appreciable amounts. The aim of this study was to evaluate the wound healing potential of <em>Emilia sonchifolia</em> on excision wounds induced in experimental rats. Excision wounds were created in male Wistar rats and were treated with <em>Emilia sonchifolia</em> ointment. Topical application of <em>Emilia sonchifolia</em> for 14 days s

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Shakila Shabbeer Shaikh, Krishna Murthy, Rajkumar V. Shete, and Rahul S. Solunke. "Comparative evaluation of wound healing activity of tilvadi ghrita and durva ghrita on diabetic wound model in rats." International Journal of Research in Pharmaceutical Sciences 10, no. 4 (2019): 3376–84. http://dx.doi.org/10.26452/ijrps.v10i4.1647.

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Previous studies proved the wound healing potential of Tilvadi Ghrita (TG) and Durva Ghrita (DG) on normal wounds, so this study was conducted to investigate wound healing activity of TG and DG on diabetic wound model in rats. Forty-eight adult female Wistar rats in eight groups were used. Alloxan was used to induce diabetes in diabetic groups. Excision wound was made on the dorsal shaved surface of rats, and then Framycetin sulfate cream (FSC) 10%, TG and DG were applied in control and treatment groups. While in normal control and diabetic control groups, no medication was done. Wound photogr

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Cao, Jiafu, Mingzhi Su, Nurhasni Hasan, et al. "Nitric Oxide-Releasing Thermoresponsive Pluronic F127/Alginate Hydrogel for Enhanced Antibacterial Activity and Accelerated Healing of Infected Wounds." Pharmaceutics 12, no. 10 (2020): 926. http://dx.doi.org/10.3390/pharmaceutics12100926.

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Nitric oxide (NO), a highly reactive and lipophilic molecule, is one of the molecules present in the wound environment and implicated as an important regulator in all phases of wound healing. Here, we developed an NO-releasing thermoresponsive hydrogel (GSNO-PL/AL) composed of S-nitrosoglutathione (GSNO), pluronic F127 (PL), and alginate (AL) for the treatment of infected wounds. The GSNO was incorporated into the thermoresponsive PL/AL hydrogel, and differential scanning calorimetry techniques were used for the hydrogel characterization. The hydrogel was assessed by in vitro NO release, antib

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Sonali, Gurav* Preeti Kale Snehal Jamdade Shreya kamble Shubham Patil Arati Mali Aishwarya Kachare Pratik Kale. "In-Vitro wound healing activity using cell line by extraction of Cinnamomum tamala." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 4993–5007. https://doi.org/10.5281/zenodo.15556450.

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Wound healing is a dynamic and multifaceted biological process involving cellular, molecular, and tissue-level mechanisms. Despite advances in modern medicine, effective management of chronic wounds particularly those associated with diabetes, immune dysfunction, and aging remains a significant clinical challenge. Chronic wounds, including pressure sores and diabetic foot ulcers, contribute substantially to global morbidity, mortality, and healthcare costs. Current treatment options are often inadequate, resulting in prolonged healing, increased infection risk, and higher rates of amputation.

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Sim, Pivian, Xanthe L. Strudwick, YunMei Song, Allison J. Cowin, and Sanjay Garg. "Influence of Acidic pH on Wound Healing In Vivo: A Novel Perspective for Wound Treatment." International Journal of Molecular Sciences 23, no. 21 (2022): 13655. http://dx.doi.org/10.3390/ijms232113655.

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There has been little understanding of acidification functionality in wound healing, highlighting the need to study the efficacy of wound acidification on wound closure and cellular activity in non-infected wounds. This study is focused on establishing the healing potential of wound acidification in non-infected wounds. Acidic buffers, constituting either phosphoric or citric acid, were employed to modify the physiological pH of non-infected full-thickness excisional murine wounds. Acidification of the wound by acidic buffers was found to be an effective strategy to improve wound healing. A si

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Shree, Muthu Karuppan Gayathri, Swamidurai Arul Diana Christie, and Sundaram Raj Kumar. "Development of Nano-Silver Functionalized Wound Dressings Using Wrightia tinctoria Extract for Enhanced Antibacterial Activity Against MRSA and Staphylococcus aureus." UTTAR PRADESH JOURNAL OF ZOOLOGY 45, no. 22 (2024): 205–17. https://doi.org/10.56557/upjoz/2024/v45i224674.

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Wound infections remain a major source of postoperative morbidity, accounting for about a quarter of the total number of nosocomial infections. This leads to errors in establishing the true incidence of their occurrence but undoubtedly decreases the overall real cost and length of hospital stay. The healing of defected skin tissue is a complex process, especially for chronic wounds. Poor healing of these wounds may cause extensive suffering and high cost for patients. Traditional wound dressings are typically designed for a single function and they cannot satisfy all requirements for the whole

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Süntar, Ipek, Ufuk Koca, Hikmet Keleş, and Esra Küpeli Akkol. "Wound Healing Activity ofRubus sanctusSchreber (Rosaceae): Preclinical Study in Animal Models." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–6. http://dx.doi.org/10.1093/ecam/nep137.

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Young shoots ofRubusspecies have been used for healing of wounds, infected insect bites and pimples in folk medicine for ages. In order to evaluate the wound healing activity ofRubus sanctus, four different extracts were prepared from the whole aerial parts of the plant by usingn-hexane, chloroform, ethyl acetate and methanol, respectively. Incision wound healing model by using tensiometer on rats and excision model on mice were employed to assess the activity. Remarkable wound healing activity was observed with the ointment formulation of the methanol extract at 1% concentration on the mentio

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Chokpaisarn, Julalak, Sasitorn Chusri, Thanaporn Amnuaikit, Wandee Udomuksorn, and Supayang Piyawan Voravuthikunchai. "Potential wound healing activity of Quercus infectoria formulation in diabetic rats." PeerJ 5 (July 24, 2017): e3608. http://dx.doi.org/10.7717/peerj.3608.

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Background Quercus infectoria G. Olivier (Fagaceae) nutgalls have been widely employed in traditional Asian medicine for several treatments, especially wounds and skin disorders. However, the effects of this plant on wound healing have not yet been clearly elucidated. This present work was focused on utilization of Quercus infectoria (Qi) as a topical agent for chronic wound treatment. Methods Twenty Qi formulations (QiFs) were pharmaceutically formulated and antibacterial activity of all formulations was performed. The best formulation based on an antibacterial activity was selected for evalu

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Choo, Jung Ha, Daehyun Kim, Kyoungin Min, So Young Lee, and Nae Gyu Kang. "Pogostemon cablin Extract Promotes Wound Healing through OR2AT4 Activation and Exhibits Anti-Inflammatory Activity." Current Issues in Molecular Biology 46, no. 8 (2024): 9136–48. http://dx.doi.org/10.3390/cimb46080540.

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Skin healing occurs through an intricate process called wound healing which comprises four phases: coagulation and hemostasis, inflammation, cellular proliferation, and remodeling. Chronic wounds often arise because of prolonged or excessive inflammation, which hinders the healing process and wound closure. Despite the recognized efficacy of Pogostemon cablin (patchouli) in wound healing, the precise mechanism of action of Pogostemon cablin extract (PCE) on inflammation and wound healing remains poorly understood. In this study, we investigated the effects of PCE on cell proliferation and woun

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Akimbekov, Nuraly, Zulhair A. Mansurov, J. Jandosov, et al. "Wound Healing Activity of Carbonized Rice Husk." Advanced Materials Research 602-604 (December 2012): 1196–99. http://dx.doi.org/10.4028/www.scientific.net/amr.602-604.1196.

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The carbonized rice husk (CRH) was evaluated for its wound healing activity in rats using excision models. In this study, the influences of CRH on wound healing in rat skin in vivo and cellular behavior of human dermal fibroblasts in vitro were investigated. The obtained results showed that the CRH treatment promoted wound epithelization in rats and exhibited moderate inhibition of cell proliferation in vitro. CRH with lanolin oil treated wounds were found to epithelize faster as compared to controls.

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DALE, PAUL D., JONATHAN A. SHERRATT, and PHILIP K. MAINI. "CORNEAL EPITHELIAL WOUND HEALING." Journal of Biological Systems 03, no. 04 (1995): 957–65. http://dx.doi.org/10.1142/s021833909500085x.

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We propose a reaction-diffusion model of the mechanisms involved in the healing of corneal surface wounds. The model focuses on the stimulus for increased mitotic and migratory activity, specifically the role of epidermal growth factor. We determine an analytic approximation for the speed of travelling wave solutions of the model in terms of the parameters and verify the results numerically. By comparing the predicted speed with experimentally measured healing rates, we conclude that serum-derived factors can alone account for the overall features of the healing process, but that the supply of

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Mothilal K, Akila CR, Mahender K, Chaitanya Kumar K, and Ravi D. "Comparison of the ficus for the wound healing activity in various species." International Journal of Research in Phytochemistry and Pharmacology 10, no. 4 (2020): 67–70. http://dx.doi.org/10.26452/ijrpp.v10i4.1381.

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Injuries and wounds are any sorts of damage to the skin or subcutaneous tissue. Usually, any wounds of such sorts are self-healed. Sometimes, there may be a delay in healing, and that delay is caused due to the functional delays in various processes of wound healing. All the Ficus plants show similar activities like the antioxidant, anti-inflammatory and wound healing properties 7including skin conditions like ulcers and rheumatism. The anthelmintic property and immunomodulatory are also seen. The herbal extracts of the same family of Ficus in different plants were investigated for the wound h

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Chu, Andy S., Barbara Delmore, and Ernest S. Chiu. "High-Quality Dietary Protein: The Key to Healthy Granulation Tissue." Advances in Skin & Wound Care 37, no. 10 (2024): 520–27. http://dx.doi.org/10.1097/asw.0000000000000210.

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ABSTRACT Wound healing is a complex process, particularly for full-thickness, chronic wounds. The processes of wound healing phases require support in order for wound healing to progress and be successful. Chronic wounds present a particular conundrum because they represent a dysfunction or interruption generally occurring between the inflammatory and proliferative phases. This progress remains delayed until the dysfunction is addressed. Older patients and those who are critically ill are generally most at risk of developing a chronic wound. A nonhealing wound is associated with increased heal

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Ramey-Ward, Allison N., Shakesia Smith, Howard Walthall, and Thomas H. Barrows. "Human Keratin Matrices Suppress Matrix Metalloproteinase Activity to Support Wound Healing." International Journal of Molecular Sciences 25, no. 23 (2024): 12898. https://doi.org/10.3390/ijms252312898.

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Elevated protease activity is a hallmark of non-healing chronic wounds. Though multiple biomaterials exist that are successful in treating wounds, their roles in modulating the enzymatic environment of the wound are only beginning to be elucidated. Because keratin has long been known to be resistant to degradation by most enzymes, we studied a keratin biomaterial, the human keratin matrix (HKM), in the presence of enzymes identified to contribute to wound chronicity: neutrophil-derived elastase (NE), matrix metalloproteinase 1 (MMP-1), and MMP-9. Upon finding the suppression of MMP-9 activity

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Demilew, Wubante, Getnet Mequanint Adinew, and Seyfe Asrade. "Evaluation of the Wound Healing Activity of the Crude Extract of Leaves of Acanthus polystachyus Delile (Acanthaceae)." Evidence-Based Complementary and Alternative Medicine 2018 (June 11, 2018): 1–9. http://dx.doi.org/10.1155/2018/2047896.

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Background. Medicinal plants play indispensable roles to treat various ailments. Acanthus polystachyus is one of the medicinal plants used traditionally for treatment of wounds. However, there were no scientific reports documented so far on the wound healing activities of this plant. Thus, the present study provides a scientific evaluation for the wound healing potential of the crude extract of A. polystachyus leaves. Methods. The crude extraction was carried out using 80% methanol. The crude extract was prepared in 5% (w/w) and 10% (w/w) ointment and evaluated for wound healing activity using

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Sofrona, Evgenia, Leto-Aikaterini Tziveleka, Maria Harizani, et al. "In Vivo Evaluation of the Wound Healing Activity of Extracts and Bioactive Constituents of the Marine Isopod Ceratothoa oestroides." Marine Drugs 18, no. 4 (2020): 219. http://dx.doi.org/10.3390/md18040219.

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Wound healing is a fundamental response to tissue injury and a number of natural products has been found to accelerate the healing process. Herein, we report the preparation of a series of different polarity (organic and aqueous) extracts of the marine isopod Ceratothoa oestroides and the in vivo evaluation of their wound healing activity after topical administration of ointments incorporating the various extracts on wounds inflicted on SKH-hr1 hairless mice. The most active extract was fractionated for enrichment in the bioactive constituents and the fractions were further evaluated for their

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Sruthi, Mrs R. "IN VITRO CELL CYTOTOXICITY AND WOUND HEALING ACTIVITY OF TOPICAL FILM FORMING HYDROGEL OF PAPAIN UREA IN VERO CELLS." YMER Digital 21, no. 02 (2022): 332–44. http://dx.doi.org/10.37896/ymer21.02/34.

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Wounds, whether acute or chronic, are one of the most common health problems worldwide, and medicative drugs are frequently used in wound healing. More research into wound treatment is being conducted at a rapid pace. For some wound types, enzymatic debridement of nonviable tissue remains the most effective debridement option. In theory, topical enzymes have been used in this therapy to remove necrotic tissue in the wound bed by digesting and dissolving the devitalized tissue. Papain, a plant-derived enzyme with a long history of clinical success, is one of these enzymes. The formulation of pa

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Alam, Fahmida, Md Asiful Islam, Siew Hua Gan, and Md Ibrahim Khalil. "Honey: A Potential Therapeutic Agent for Managing Diabetic Wounds." Evidence-Based Complementary and Alternative Medicine 2014 (2014): 1–16. http://dx.doi.org/10.1155/2014/169130.

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Diabetic wounds are unlike typical wounds in that they are slower to heal, making treatment with conventional topical medications an uphill process. Among several different alternative therapies, honey is an effective choice because it provides comparatively rapid wound healing. Although honey has been used as an alternative medicine for wound healing since ancient times, the application of honey to diabetic wounds has only recently been revived. Because honey has some unique natural features as a wound healer, it works even more effectively on diabetic wounds than on normal wounds. In additio

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