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Journal articles on the topic 'Wound patterns'

Author: Grafiati

Published: 30 June 2021

Last updated: 1 February 2022

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1

Frilasari, Heni, Noer Saudah, Veryudha Eka Prameswari, Yeni Nur Azizah, and Byba Melda Suhita. "Nutritional Pattern And Healing Of Perineum Wound On Postpartum Period." Journal Of Nursing Practice 3, no. 2 (2020): 172–80. http://dx.doi.org/10.30994/jnp.v3i2.85.

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Background: Postpartum period was the return of uterine implants such as before pregnancy which takes 6 weeks after born. Good nutrition patterns would speed healing wound perineum. The high nutritional content of calories, protein, fluids, and vitamins needed for speed up perineal wound closure.Purpose: This study aimed to determine the relationship of postnatal maternal nutritional patterns with the healing of perineal wounds in Puri community health center Mojokerto.Methods: Analytical research design with Cross-Sectional. The population used postpartum mothers with perineal injuries. The sampling technique was through consecutive. The sample size was 90 respondents. The independent variable was nutrition pattern and the dependent variable was perineal wound healing. The instrument used was a questionnaire sheet postpartum maternal nutrition pattern and observation sheets for perineal wound healing.Results: The results showed 56 respondents (63.3%) had good nutrition patterns and good perineal wound healing, 27 respondents (30%) had poor nutrition patterns and moderate perineal wound healing, as many as 7 respondents (6.7%) had nutritional patterns less and bad perineal wound healing. Chi-Square statistical test results showed ρ (0,000) <α 0.05.Conclusion: It could concluded that there was a relationship between the nutritional pattern of the puerperal mother with the healing of perineal wounds. High caloric, protein, fluid and mineral intake and vitamins in the puerperium mother will accelerate the process of new cell regeneration so that the puerperal perineal wound heals faster. Postpartum mothers are expected to maintain a nutritional pattern for healing the perineal wound and not do certain food restrictions during the puerperium

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West, M. H., S. Hayne, and R. E. Barsley. "Wound patterns: detection, documentation and analysis." Journal of Clinical Forensic Medicine 3, no. 1 (1996): 21–27. http://dx.doi.org/10.1016/s1353-1131(96)90041-3.

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3

Dua, H. S., and J. V. Forrester. "Clinical Patterns of Corneal Epithelial Wound Healing." American Journal of Ophthalmology 104, no. 5 (1987): 481–89. http://dx.doi.org/10.1016/s0002-9394(14)74105-4.

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4

Lucas, Valentina Sage, Nancy McCain, R. K. Elswick, and Andrea L. Pozez. "Perceived Stress and Surgical Wound Cytokine Patterns." Plastic Surgical Nursing 38, no. 2 (2018): 55–72. http://dx.doi.org/10.1097/psn.0000000000000223.

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Murray, J. D., J. Cook, R. Tyson, and S. R. Lubkin. "Spatial pattern formation in biology: I. Dermal wound healing. II. Bacterial patterns." Journal of the Franklin Institute 335, no. 2 (1998): 303–32. http://dx.doi.org/10.1016/s0016-0032(97)00034-3.

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6

G., Dayanand, and Anil Kannur. "Comparative Analysis of Techniques for the Recognition of Stabbed Wound and Accidental Wound Patterns." International Journal of Computer Applications 182, no. 13 (2018): 34–41. http://dx.doi.org/10.5120/ijca2018917769.

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7

Flattau, Anna, Hanna Gordon, Giacomo Vinces, William J. Ennis, and Caterina P. Minniti. "Use of a National Electronic Health Record Network to Describe Characteristics and Healing Patterns of Sickle Cell Ulcers." Advances in Wound Care 7, no. 8 (2018): 276–82. http://dx.doi.org/10.1089/wound.2018.0788.

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8

Bodnár, Edina, Edina Bakondi, Katalin Kovács, et al. "Redox Profiling Reveals Clear Differences between Molecular Patterns of Wound Fluids from Acute and Chronic Wounds." Oxidative Medicine and Cellular Longevity 2018 (November 18, 2018): 1–12. http://dx.doi.org/10.1155/2018/5286785.

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Wound healing is a complex multiphase process which can be hampered by many factors including impaired local circulation, hypoxia, infection, malnutrition, immunosuppression, and metabolic dysregulation in diabetes. Redox dysregulation is a common feature of many skin diseases demonstrated by virtually all cell types in the skin with overproduction of reactive oxygen and nitrogen species. The objective of this study was to characterize the redox environment in wound fluids and sera from patients suffering from chronic leg ulcers (n=19) and acute wounds (bulla fluids from second degree burns; n=11) with serum data also compared to those from healthy volunteers (n=7). Significantly higher concentrations of TNF-α, interleukine-8, vascular endothelial growth factor, and lactate dehydrogenase (measure of cell damage) were found in fluids from chronic wounds compared to acute ones. The extent of protein carbonylation (measure of protein oxidation), lipid peroxidation, and tyrosine nitration (indicator of peroxynitrite production) was similar in acute and chronic wound fluids, while radical scavenging activity and glutathione (GSH) levels were elevated in chronic wound fluids compared to acute wounds. Sera were also assessed for the same set of parameters with no significant differences detected. Nitrotyrosine (the footprint of the potent oxidant peroxynitrite) and poly(ADP-ribose) (the product of the DNA damage sensor enzyme PARP-1) could be detected in wound biopsies. Our data identify multiple signs of redox stress in chronic wounds with notable differences. In chronic wounds, elevations in antioxidant levels/activities may indicate compensatory mechanisms against inflammation. The presence of nitrotyrosine and poly(ADP-ribose) in tissues from venous leg ulcers indicate peroxynitrite production and PARP activation in chronic wounds.

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Truby, Paul R. "Separation of wound healing from regeneration in the cockroach leg." Development 85, no. 1 (1985): 177–90. http://dx.doi.org/10.1242/dev.85.1.177.

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It has been shown that after a critical point in the moult cycle of a cockroach, wound healing can occur but regeneration of pattern does not take place until the following intermoult period. Leg removal after the critical point is used to separate the processes of wound healing and leg regeneration. This permits the study of patterns of cell division resulting from wound healing to be distinguished from those involved in leg regeneration. During wound healing, cell division occurs in the epidermal cells of approximately the distal half of the trochanter. The cells then return to the resting state until after the next ecdysis. Regeneration starts with cell division occurring in the distal half of the trochanter, and then spreading to include cells of the proximal trochanter and distal coxa. This spread and the following patterns of growth and redifferentiation appear to be the same as for regeneration following leg removal prior to the critical point, with the more distal structures completing early stages of regeneration first. Scanning electron micrographs of the cuticle of the trochanter after the ecdysis following leg removal support the evidence from the patterns of cell division in suggesting that the distal half of the trochanter is dedifferentiated during wound healing.

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Szpaderska, A. M., C. G. Walsh, M. J. Steinberg, and L. A. DiPietro. "Distinct Patterns of Angiogenesis in Oral and Skin Wounds." Journal of Dental Research 84, no. 4 (2005): 309–14. http://dx.doi.org/10.1177/154405910508400403.

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Clinical observation suggests that oral mucosal wounds heal faster than skin; however, little is known about the site-specific differences. Since fetal skin wounds heal rapidly, but are less vascular than adult wounds, we hypothesized that less robust wound angiogenesis might be observed in healing oral mucosa. This study investigated angiogenesis in equivalent-size oral and skin murine wounds. Change in wound bed vascularity was significantly lower in oral wounds than in skin. Also, vascular endothelial growth factor (VEGF) levels were less in oral than cutaneous wounds. Because keratinocytes are a prominent source of VEGF in wounds, we compared VEGF production by oral and epidermal keratinocytes in vitro. Significantly higher levels of VEGF protein and mRNA were observed in epidermal keratinocytes than in oral keratinocytes after 18 hrs of hypoxia. This study demonstrates distinct angiogenesis patterns in oral and skin wounds and intrinsic site-specific differences in VEGF production by keratinocytes.

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Betz, P., and W. Eisenmenger. "Comparison of Wound Patterns in Homicide and Dyadic Death." Medicine, Science and the Law 37, no. 1 (1997): 19–22. http://dx.doi.org/10.1177/002580249703700105.

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A comparison of patterns of injuries between homicides and cases of dyadic death was performed. In 195 homicides, 139 deceased (71%) showed exclusively one type of trauma (mainly gunshot wounds) whereas two and even three types of trauma were detectable in 45 (23%) and 11 (6%) of the cases, respectively. In contrast, 18 out of 20 victims of dyadic death (90%) showed one type of injury (mainly gunshot wounds) and only two victims showed two types of injury. Even though different methods of killing seem to be unusual in dyadic death, even in cases with more than one victim and evidence of different types of injuries, such features cannot provide reliable information useful for a differentiation between homicide and extended suicide.

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Chowdury, Misbah Ul Hoq, Ali Md Shariful Alam Rubel, Md Samir Uddin, Kanta Deb, and Chowdhury Rifat Jahan. "Injury Pattern in Fatal Cases of Stab Wound." Medicine Today 31, no. 2 (2019): 76–79. http://dx.doi.org/10.3329/medtoday.v31i2.41955.

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Introduction: Stabbing is the most common method of homicide as like as other parts of the world. Precise examination of stab wound along with the type of other wounds considering their site, shape, number and orientation of the wounds in relation to each other etc. provide a number of clues which may be of paramount importance in reconstruction and interpretation of the whole events. Materials and Methods: This is a retrospective study carried out in Forensic Medicine Department of Sylhet M.A.G. Osmani Medical College, Sylhet from July 2010 to June 2011 and in the year of July 2017 to June 2018 to observe different patterns of injuries in fatal cases of stab wound. 20 autopsies were included in this study using random sampling. Results: Male(90%) are more victimized than female. The pattern of injury that found to be most common is the penetrating wound of the chest injuring either lung or heart. Second most common injury pattern is the penetrating wound of the chest or abdomen injuring eitherstomach or liver.Another pattern is widely scattered multiple stab wounds both on front and back of the body and the fourth pattern is stab wound of the lower limb causing division of a major blood vessel. Conclusion: The stab wound is deeper than it is long or wide. This means depth is the greatest dimension in case of Stab wound and that is where the danger lies as it is evident in this study. Medicine Today 2019 Vol.31(2): 76-79

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13

Xu, Jiazhong, Lingxing Wang, Meijun Liu, Jiande Tian, Baoquan Liu, and Xinliang Liu. "Patterns design of filament wound spherical structure based on a new winding strategy." Journal of Reinforced Plastics and Composites 38, no. 7 (2018): 314–22. http://dx.doi.org/10.1177/0731684418817147.

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In order to satisfy the collision-resistance requirements for the stiffness and strength of collision-protected spherical structure of marine structure platforms, a new winding strategy for spherical structure was proposed, which can make the thickness distribution of the filament wound layer of the spherical structure relatively even, and the polar opening can be covered by the filament wound layer. In this paper, the filament wound trajectory equation and the approaches for winding parameters design of spherical structures were presented. The influence of different partitions on the thickness distribution of the filament wound layer for spherical structure was analyzed. The optimal partition was adjusted according to the even distribution condition of the filament wound patterns, and the simulation of the new winding strategy of the spherical structure, dry yarn filament wound experiment and the wet filament wound experiment was carried out with adjusted partitions. The results show that when adopting the new winding strategy, the obtained winding pattern is stable. The feasibility of the new winding strategy is verified, which can consequently improve the structural bearing capability of spherical structure.

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Chesham, J. S., and D. J. Platt. "Patterns of wound colonisation in patients with peripheral vascular disease." Journal of Infection 15, no. 1 (1987): 21–26. http://dx.doi.org/10.1016/s0163-4453(87)91326-0.

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Guo, Kaite, Lihua Wen, Jinyou Xiao, et al. "Design of winding pattern of filament-wound composite pressure vessel with unequal openings based on non-geodesics." Journal of Engineered Fibers and Fabrics 15 (January 2020): 155892502093397. http://dx.doi.org/10.1177/1558925020933976.

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In this article, we proposed a new approach to design the winding patterns of filament-wound composite pressure vessel with unequal polar openings with non-geodesics. To ensure the continuity of winding angles between trajectories along the cylinder and the dome, the non-geodesics for cylindrical part were used. The developed winding patterns of the vessels were simulated using the MATLAB software to verify the feasibility of the acquired trajectories. To demonstrate the performance in designing the winding path for big polar ratios, we analyzed vessels with polar pole ratios of 1:2–1:4, respectively. The developed winding patterns have successfully achieved uniform fiber distributions along the mandrel without severe overlap, except for the polar pole regions. To avoid the severe overlap between filament bands, we further studied the relationship among the winding pattern, bandwidth, and the number of tangent points, and derived a suitable bandwidth based on the winding pattern. These simulated results proved the effectiveness of the developed method in design of winding pattern with unequal polar openings.

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16

Goliger, J. A., and D. L. Paul. "Wounding alters epidermal connexin expression and gap junction-mediated intercellular communication." Molecular Biology of the Cell 6, no. 11 (1995): 1491–501. http://dx.doi.org/10.1091/mbc.6.11.1491.

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We show that connexin expression and in vivo patterns of communication were dramatically altered in response to epidermal wounding. Six hours after injury, Cx26 was up-regulated in the differentiated cells proximal to the wound, but was down-regulated in cells located at the wound edge. In contrast, Cx31.1 and Cx43 were down-regulated in cells both peripheral to and at the wounded edge. These patterns of altered connexin expression were detectable as early as 2 h after wounding and were most pronounced in 24-h old wounds. Increased expression of Cx26 was still evident in the hyperproliferative epidermis of 6-day old wounds. In vivo dye transfer experiments with Lucifer yellow and neurobiotin confirmed that junctional communication patterns were altered in ways consistent with changes in connexin expression. The data thus suggest that intercellular communication is intimately involved in regulating epidermal wound repair.

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Tkachenko, P. I., S. A. Belokon, N. M. Lokhmatova, O. B. Dolenko, Yu V. Popelo, and N. M. Korotych. "PATTERNS IN WOUND HEALING PROCESS AFTER BRANCIAL CLEFT CYST EXCISION IN CHILDREN." Ukrainian Dental Almanac, no. 2 (June 29, 2021): 68–72. http://dx.doi.org/10.31718/2409-0255.2.2021.13.

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The course of the wound healing process after surgical intervention on brancial cleft cyst excision should be considered as a stereotyped inflammatory-reparative reaction of the body, characterized by staged aseptic inflammation, regeneration and fibrosis. Clinically and even morphologically, it is difficult to determine the stages of the wound healing process in the temporal aspect, since they are consistent and interconnected. Purpose. The paper is aimed at evaluation of the wound healing process according to clinical indicators in children after branchial cleft cyst excision. Methods and Material. 26 children aged from 5 to 17 years old with branchial cleft cysts have been examined and treated. In the postoperative period, the nature, amount of exudate and its cell composition has been determined; skin contact thermometry has been performed at 4 points around the wound at a distance of 1 cm. Results. The first manifestations of the disease coincided with the course of acute respiratory viral diseases in 8 children (30.8%); association with ENT pathology was observed in 3 (11.5%) children and the cystic masses emerged spontaneously in 15 cases (57.7%). They were localized with almost the same incidence on the left and right, but the vast majority (21 cases (80.7%)) was located anteriorly the sternocleidomastoid muscle and in 5 (19.3%) cases behind it. Ultrasound examination, made in 21 patients (80.8%), has revealed the presence of cystic masses with clear contours, hypoechoic structure and fine-grained inclusions, and the wall thickness varied from 1 to 3 mm. In 5 doubtful cases (19.2%) a puncture biopsy was performed. On 1st day after surgery, hyperemia around the wound was moderate in 15 children (57.7%); it was insignificant in 8 (30.8%) children and it was absent in 3 (11.5%) children. At the same time all children experienced collateral edema of various localization and painful modality. In the impression smears, a significant number of neutrophils, a moderate number of lymphocytes and erythrocytes was detected, which were prominent against the background of a loose substrate. The temperature of the wound area was 36.24 ± 0.07˚C, which was higher compared to the control group (34.71 ± 0.12˚C). On 3rd day, the corolla of hyperemia around the wound was not detected in 18 patients (69.2%), and its narrowing was recorded in 6 (23.1%) cases and it was persistent in 2 (7.7%) cases. On palpation, severe, moderate and weak pain on the wound area was experienced by 2 (7.7%), 15 (57.7%) and 9 (36.4%) children, respectively. The cytograms of the exudate showed a reduced quantity of neutrophils, erythrocytes and lymphocytes. Two children showed elevated quantity of destructured neutrophils and local temperature to 37.21 ± 0.16 ° C, which required medical adjustments. A narrow corolla of hyperemia around the wound, slight edema and moderate pain was detected on 7th day only in 2 children. In all patients, palpation revealed tissue compaction along the wound canal, onset of epithelialization, and the cytograms revealed the presence of sporadic neutrophils. The temperature of the skin around the wound reached 35.74 ± 0.11˚C, which was almost similar to controls (34.21 ± 0.08˚C). In all cases, the wounds healed with primary tension. Thus, the nature of the dynamics of wound healing after brancial cleft cyst extirpation in children can be successfully controlled by the prominence of the main clinical signs, the findings of the study of cellular composition of wound exudate and local temperature measuring. The perspectives of further research are associated with availability and simplicity of the methods in terms of their application in everyday clinical practice.

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Guo, Zhangxin, Zhonggui Li, Junjie Cui, Yongcun Li, and Yunbo Luan. "The effect of winding patterns on the mechanical behavior of filament-wound cylinder shells." Multidiscipline Modeling in Materials and Structures 16, no. 3 (2019): 508–18. http://dx.doi.org/10.1108/mmms-03-2019-0059.

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Purpose The purpose of this paper is to present a finite element analysis (FEA) of filament-wound composites, as well as application of these materials. Design/methodology/approach In this paper, a new finite element method of filament-wound composite is presented. The stress and strain fields in the composite cylinders are analyzed using the ABAQUS software packages for considering the filament undulation and crossover. The paper presented results of buckling load of composite cylinders with different types of filament-winding patterns. Findings The result of the example shows that the stress distributions are uniform along the cylinder length and around the circumference when the analytical approach is based on the conventional FEA. The stress distributions are not uniform along the cylinder length and around the circumference for considering the filament undulation and crossover. The stress units are arranged in a regular geometric pattern around circumference and along the axis of rotation. The analysis of the effect of filament-winding mosaic patterns on the mechanical characteristics of composite cylindrical is presented in the paper. Originality/value The stress and strain fields in the composite cylinders were analyzed for considering the filament undulation and crossover. The buckling load of composite cylinders with different types of filament-winding patterns was presented in this paper.

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Zulueta-Coarasa, Teresa, and Rodrigo Fernandez-Gonzalez. "Dynamic force patterns promote collective cell movements during embryonic wound repair." Nature Physics 14, no. 7 (2018): 750–58. http://dx.doi.org/10.1038/s41567-018-0111-2.

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Rubinstein, C., and W. J. Russell. "WOUND CLOSURE AND SUTURING PATTERNS: A VECTOR ANALYSIS OF SUTURE TENSION." ANZ Journal of Surgery 62, no. 9 (1992): 733–37. http://dx.doi.org/10.1111/j.1445-2197.1992.tb07072.x.

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21

McGee, Michael B. "Unusual Blunt Force Wound Patterns due to a Hexagonal Steel Bar." American Journal of Forensic Medicine and Pathology 12, no. 2 (1991): 149–52. http://dx.doi.org/10.1097/00000433-199106000-00011.

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22

Feezor, Robert J., Heather N. Paddock, Henry V. Baker, et al. "Temporal patterns of gene expression in murine cutaneous burn wound healing." Physiological Genomics 16, no. 3 (2004): 341–48. http://dx.doi.org/10.1152/physiolgenomics.00101.2003.

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The global changes in gene expression in injured murine skin were characterized following a second-degree scald burn. Dorsal skin was harvested from uninjured and from burned mice at 2 h and at 3 and 14 days following immersion in 65°C water for 45 s. Gene expression was surveyed using an Affymetrix U74Av2 GeneChip, and patterns of gene expression were analyzed using hierarchical clustering and supervised analysis. Burn injury produced significant alterations in the expression of a number of genes, with the greatest changes seen 3 and 14 days after the scald burn. Using a supervised analysis with a false discovery rate of 1% or 5%, differences in the expression of 192 or 1,116 genes, respectively, discriminated among the unburned skin and the three time points after the burn injury. Gene expression was primarily a transient and time-dependent upregulation. The expression of only 24 of the 192 discriminating genes was downregulated after the burn injury. No gene exhibited a sustained increase in expression over the entire 14 days following the burn injury. Gene ontologies revealed an integrated upregulation of inflammatory and protease genes at acute time intervals, and a diminution of cytoskeletal and muscle contractile genes at 3 or 14 days after the injury. Following a second-degree scald burn, global patterns of gene expression in the burn wound change dramatically over several weeks in a time-dependent manner, and these changes can be categorized based on the biological relevance of the genes.

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Feezor, R. J., H. N. Paddock, H. V. Baker, L. L. Moldawer, G. S. Schultz, and D. M. Mozingo. "TEMPORAL PATTERNS OF GENE EXPRESSION IN MURINE CUTANEOUS BURN WOUND HEALING." Shock 21, Supplement (2004): 138. http://dx.doi.org/10.1097/00024382-200403001-00549.

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Stewart, Laveta, Ping Li, Maj Dana M. Blyth, et al. "Antibiotic Practice Patterns for Extremity Wound Infections among Blast-Injured Subjects." Military Medicine 185, Supplement_1 (2020): 628–36. http://dx.doi.org/10.1093/milmed/usz211.

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ABSTRACT Introduction We examined antibiotic management of combat-related extremity wound infections (CEWI) among wounded U.S. military personnel (2009–2012). Methods Patients were included if they sustained blast injuries, resulting in ≥1 open extremity wound, were admitted to participating U.S. hospitals, developed a CEWI (osteomyelitis or deep soft-tissue infections) within 30 days post-injury, and received ≥3 days of relevant antibiotic (s) for treatment. Results Among 267 patients, 133 (50%) had only a CEWI, while 134 (50%) had a CEWI plus concomitant non-extremity infection. In the pre-diagnosis period (4–10 days prior to CEWI diagnosis), 95 (36%) patients started a new antibiotic with 28% of patients receiving ≥2 antibiotics. During CEWI diagnosis week (±3 days of diagnosis), 209 (78%) patients started a new antibiotic (71% with ≥2 antibiotics). In the week following diagnosis (4–10 days after CEWI diagnosis), 121 (45%) patients started a new antibiotic with 39% receiving ≥2 antibiotics. Restricting to ±7 days of CEWI diagnosis, patients commonly received two (35%) or three (27%) antibiotics with frequent combinations involving carbapenem, vancomycin, and fluoroquinolones. Conclusions Substantial variation in antibiotic prescribing patterns related to CEWIs warrants development of combat-related clinical practice guidelines beyond infection prevention, to include strategies to reduce the use of unnecessary antibiotics and improve stewardship.

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van Beurden, Hugo E., Patricia A. M. Snoek, Johannes W. Von den Hoff, Ruurd Torensma, Jaap C. Maltha, and Anne M. Kuijpers-Jagtman. "Dynamic protein expression patterns during intraoral wound healing in the rat." European Journal of Oral Sciences 113, no. 2 (2005): 153–58. http://dx.doi.org/10.1111/j.1600-0722.2005.00200.x.

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Ambade, Vipul Namdeorao, and Hemant Vasant Godbole. "Comparison of wound patterns in homicide by sharp and blunt force." Forensic Science International 156, no. 2-3 (2006): 166–70. http://dx.doi.org/10.1016/j.forsciint.2004.12.027.

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Stabla, Paweł, Michał Smolnicki, and Wojciech Błażejewski. "The Numerical Approach to Mosaic Patterns in Filament-Wound Composite Pipes." Applied Composite Materials 28, no. 1 (2021): 181–99. http://dx.doi.org/10.1007/s10443-020-09861-z.

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Chen, Lin, Alyne Simões, Zujian Chen, et al. "Overexpression of the Oral Mucosa-Specific microRNA-31 Promotes Skin Wound Closure." International Journal of Molecular Sciences 20, no. 15 (2019): 3679. http://dx.doi.org/10.3390/ijms20153679.

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Wounds within the oral mucosa are known to heal more rapidly than skin wounds. Recent studies suggest that differences in the microRNAome profiles may underlie the exceptional healing that occurs in oral mucosa. Here, we test whether skin wound-healing can be accelerating by increasing the levels of oral mucosa-specific microRNAs. A panel of 57 differentially expressed high expresser microRNAs were identified based on our previously published miR-seq dataset of paired skin and oral mucosal wound-healing [Sci. Rep. (2019) 9:7160]. These microRNAs were further grouped into 5 clusters based on their expression patterns, and their differential expression was confirmed by TaqMan-based quantification of LCM-captured epithelial cells from the wound edges. Of these 5 clusters, Cluster IV (consisting of 8 microRNAs, including miR-31) is most intriguing due to its tissue-specific expression pattern and temporal changes during wound-healing. The in vitro functional assays show that ectopic transfection of miR-31 consistently enhanced keratinocyte proliferation and migration. In vivo, miR-31 mimic treatment led to a statistically significant acceleration of wound closure. Our results demonstrate that wound-healing can be enhanced in skin through the overexpression of microRNAs that are highly expressed in the privileged healing response of the oral mucosa.

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Gordon, S. R. "Changes in distribution of extracellular matrix proteins during wound repair in corneal endothelium." Journal of Histochemistry & Cytochemistry 36, no. 4 (1988): 409–16. http://dx.doi.org/10.1177/36.4.3279112.

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The distribution of fibronectin (FN) and laminin (LM) in non-injured and injured rat corneal endothelium in vivo was investigated by light microscopy using immunoperoxidase cytochemistry. In non-injured tissues, both FN and LM have distinct pericellular staining patterns and exhibit some diffuse cytoplasmic staining. After a circular freeze injury, cells migrating into the wound area at 24 hr lack the characteristic pericellular staining observed in non-injured cells but show cytoplasmic staining for both extracellular matrix glycoproteins. Endothelial cells on the periphery of such preparations do not partake in wound repair and retain their pericellular staining patterns. Forty-eight hours after injury, cells have filled in the wound area but are disorganized. They display intracellular FN and LM staining but do not demonstrate any pericellular staining. When observed 10 days after injury, a uniform monolayer has formed but neither FN nor LM is detected pericellularly. By 14 days post injury, endothelial cells in the wound area display pericellular FN patterns but not LM patterns. This may reflect differences in the function of each glycoprotein in maintaining the attachment of the endothelium to Descemet's membrane.

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Knickerbocker, MS, Chase, Mario F. Gomez, DO, Jose Lozada, MD, Jonathan Zadeh, MD, Eugene Costantini, MD, and Ivan Puente, MD. "Wound patterns in survivors of modern firearm related civilian Mass Casualty Incidents." American Journal of Disaster Medicine 14, no. 3 (2019): 175–80. http://dx.doi.org/10.5055/ajdm.2019.0329.

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Background: Civilian mass shooting events (CMSE) are occurring with increased frequency. Unfortunately, our knowledge of how to respond to these events is largely based on military experience and medical examiner data. While this translational knowledge has improved our basic response to such events, it is critical that we have a better understanding of the wound patterns observed and the resources utilized in civilian mass shootings. This will allow us to better prepare our systems for future events.Methods: Patients from two consecutive CMSEs presented to the same level 1 trauma center in Fort Lauderdale, Florida. The patients received by this center were studied for their wound patterns as well as the care they received while in the hospital. This included wound patterns and severity, subspecialty interventions, and hospitalization requirements.Results: Both events produced a total of 19 victims who were brought to the center as trauma activations. The events had a combined fatality rate of 55 percent. Fifty-five percent of patients also had at least one wound to an extremity, two with major vascular injuries who had field tourniquets applied. Sixty-three percent required an orthopedic intervention and 32 percent required intensive care unit (ICU) admission, half of these with prolonged ventilator support.Conclusions: Given the number of extremity wounds in these events, we should continue the efforts championed by the stop the bleed campaign. The variety and quantity of specialties involved in the care of these patients also highlights the importance of a multidisciplinary approach to preparation and implementation of care in mass shooting events.

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Azevedo, Cristiano B., José Humberto S. Almeida Jr, Heitor F. Flores, Frederico Eggers, and Sandro C. Amico. "Influence of mosaic pattern on hygrothermally-aged filament wound composite cylinders under axial compression." Journal of Composite Materials 54, no. 19 (2020): 2651–59. http://dx.doi.org/10.1177/0021998319899144.

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The mechanical response of composite structures may be affected by harsh environments, particularly when the matrix has a major contribution, e.g. with off-axis plies. This study aims at investigating the influence of the winding pattern on the axial compressive behavior of filament wound composite cylinder under hygrothermal conditioning. Carbon fiber-reinforced epoxy cylinders were manufactured via filament winding with 1/1, 3/1, and 5/1 mosaic winding patterns and submitted to distilled and artificial seawater environmental conditioning. Water uptake for each hygrothermal conditioning was periodically monitored. The winding pattern influenced both compressive strength and stiffness, and the environmental conditioning decreased strength up to ≈10%. The winding pattern with three diamonds around the circumference of the cylinders provides the properties in term of compressive strength and stiffness.

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32

Hamilton-Kemp, Thomas R., Douglas D. Archbold, Randall W. Collins, and Keshun Yu. "Emission patterns of wound volatile compounds following injury of ripe strawberry fruit." Journal of the Science of Food and Agriculture 83, no. 4 (2003): 283–88. http://dx.doi.org/10.1002/jsfa.1310.

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33

Huang, Rongkang, Xiaoxuan Zhang, Wenzhao Li, Luoran Shang, Hui Wang, and Yuanjin Zhao. "Suction Cups‐Inspired Adhesive Patch with Tailorable Patterns for Versatile Wound Healing." Advanced Science 8, no. 17 (2021): 2100201. http://dx.doi.org/10.1002/advs.202100201.

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34

Abu-Harirah, Hashem A., Audai Jamal Al Qudah, Emad Daabes, Kawther Faisal Amawi, and Haitham Qaralleh. "Multidrug-resistant Bacterial Profile and Patterns for Wound Infections in Nongovernmental Hospitals of Jordan." Journal of Pure and Applied Microbiology 15, no. 3 (2021): 1348–61. http://dx.doi.org/10.22207/jpam.15.3.25.

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Globally, multidrug-resistant bacteria affects wound infections, both hospital-acquired infections and community-acquired infections. The main isolates cultured from 607 subjects with wound infections were methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter spp. [multidrug resistant (MDR)]. Gram-negative bacteria caused most of the infections (67%) compared with gram-positive bacteria. Diabetic patients tend to have wound infections with mixed causative agents compared with non-diabetic patients.

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35

Lin, P. M., and J. A. Wickert. "Corrugation and Buckling Defects in Wound Rolls." Journal of Manufacturing Science and Engineering 128, no. 1 (2005): 56–64. http://dx.doi.org/10.1115/1.2113068.

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Sheet metal, paper, and polymer webs are often stored and processed as large rolls comprising thousands of layers. Depending on the elastic properties of the web material, the roll’s dimensions, the type of core, and the winding tension, the stresses that develop within the roll can be sufficiently high to cause local or gross buckling defects to form. For instance, the cylindrical core onto which the web is wound can collapse, a failure mode that is termed “v-buckling.” In other cases, while the core might remain intact, a group of layers interior to the roll can wrinkle into a near-sinusoidal corrugated pattern around the circumference. This paper examines such “starring” defects analytically and experimentally. Measurements on a laboratory-scale web transport system are used to validate the model, and to identify conditions where no defects occur and the roll has acceptable quality, where starring patterns develop, and where v-buckling occurs. For particular core and web materials, the tension and diameter are the primary variables that influence the roll’s stability, and demarcations between stable and buckled configurations are identified in the tension-diameter design space. A model for the elastic stability of the roll-core system is developed, in which the corrugated layers are treated as multiple rings subjected to the resultant pressure generated by the roll’s internal stresses, and to the elastic support provided by the core and neighboring web layers. At the onset of corrugation, adjacent web layers couple through surface contact which is incorporated in the model as an elastic shear layer.

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36

Arhipova, Natalija, Aris Jansons, Astra Zaluma, Talis Gaitnieks, and Rimvydas Vasaitis. "Bark stripping of Pinus contorta caused by moose and deer: wounding patterns, discoloration of wood, and associated fungi." Canadian Journal of Forest Research 45, no. 10 (2015): 1434–38. http://dx.doi.org/10.1139/cjfr-2015-0119.

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The aim of this study was to assess the extent of bark stripping wounds, subsequent wood discoloration, and associated fungi in 30-year-old Pinus contorta Douglas ex Loudon stems damaged by large game. In total, 90 trees were evaluated, and 170 bark stripping wounds of different ages (1–20 years) were measured. From each wound, wood samples were collected for subsequent fungal isolation. Thirty trees were cut to evaluate the length of the discoloration column. Of 170 injuries, 16 of them represented closed scars and 154 of them represented open wounds that exposed 4–4355 cm2 of sapwood. The wound length had a strong impact on the length of decay (r = 0.716); however, the spread of discoloration beyond the wound margin was limited (0–20 cm). The most commonly isolated fungus was Sarea difformis (Fr.) Fr. and, among the Basidiomycetes, Peniophora pini (Schleich.) Boidin. The results suggest that when planning to grow P. contorta in areas of Europe, the population size of large game animals needs to be considered, in view of potential risk of bark stripping damage.

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S, Roopashree, A. G. Prathab, and Sandeep T. "Bacteriological profile and antibiotic susceptibility patterns of wound infections in a tertiary care hospital in South India." Indian Journal of Microbiology Research 8, no. 1 (2021): 76–85. http://dx.doi.org/10.18231/j.ijmr.2021.016.

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Infections caused due to injuries are due to microbial proliferation at the wound site following skin damage. Initial testing of micro-organisms in terms of culturing and sensitivity leads to appropriate antibiotic selection and prevents escalation of antimicrobial resistance.To evaluate the bacteriological profile and antibiotic susceptibility patterns of wound infections in this single-centered study.The study included 160 patients suspected to have wound infection. Pus or tissue samples collected from patients were subjected to microbiological processing including Gram staining, culture and antibiotic susceptibility testing. Their demographic data and wound related factors (duration, nature, type) were recorded. The isolated organisms were evaluated for β-lactamase production using Extended spectrum β-lactamase (ESBL) test, Modified Hodge test for Carbapenemase and AmpC β-lactamase enzyme detection tests. Most participants were 41-60 years old (45.63%). The majority had surgical site infections (SSI, 91.25%), early infected (91.1%) and clean (67.12%) wounds. The bacterial isolation rate was 80% and 45.27% (n=67) were Gram positive isolates, out of which 47 (70.14%) were multidrug resistant. was identified as the predominant organism (n=40), where 33 among 40 were methicillin sensitive, followed by (n=30, 23.43%). Amongst the Gram negative isolates (n=81, 54.73%), 60 (74.07%) were multidrug resistant with majority being susceptible to imipenem, meropenem and amikacin. The most common pathogen associated with wound infection was Methicillin sensitive with SSI being the most common type of wound infection.

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38

Gautam, R., ML Chapagain, A. Acharya, et al. "Antimicrobial Susceptibility Patterns of Escherichia Coli From Various Clinical Sources." Journal of Chitwan Medical College 3, no. 1 (2013): 14–17. http://dx.doi.org/10.3126/jcmc.v3i1.8459.

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Escherichia coli is the major organism causing the urinary tract infection, wound infection and respiratory tract infection. A total of 2376 samples of urine, wound swab and sputum were analyzed for identification of bacterial isolates and their antimicrobial susceptibility pattern. Escherichia coli (E. coli) was isolated from 357 [15%] samples. Majority of the E.coli, 307 [85.9%], were obtained from the urine samples, followed by wound swab [8.4%] and sputum [5.6%]. High degree of resistance was observed for nalidixic acid [92.8%] followed by ceftriaxone [65.7%] and cotrimoxazole [64.6%]. The isolates were highly sensitive to imipenem (100%) followed by nitrofurantoin [90.3%] and amikacin [82.1%]. Journal of Chitwan Medical College 2013; 3(1): 14-17 DOI: http://dx.doi.org/10.3126/jcmc.v3i1.8459

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39

Renno, Isabell, Anja M. Boos, Raymund E. Horch, and Ingo Ludolph. "Changes of perfusion patterns of surgical wounds under application of closed incision negative pressure wound therapy in postbariatric patients1." Clinical Hemorheology and Microcirculation 72, no. 2 (2019): 139–50. http://dx.doi.org/10.3233/ch-180450.

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40

Lev-Yadun, Simcha. "WOUND EFFECTS ARREST WAVE PHENOMENA IN THE SECONDARY XYLEM OF RHAMNUS ALATERNUS (RHAMNACEAE)." IAWA Journal 22, no. 3 (2001): 295–300. http://dx.doi.org/10.1163/22941932-90000286.

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Wounding and partial girdling of stems of Rhamnus alaternus L. inhibited the formation of vessel wave patterns that are normally formed in the secondary xylem of this species. The patterns returned to normal in some of the trees in the first or in the second year after wounding. The possible hormonal regulatory mechanisms involved in the histological changes are discussed.

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Kopani, Kamden R., Michael A. Page, Jeff Holiman, Armando Parodi, Bernie Iliakis, and Winston Chamberlain. "Femtosecond laser-assisted keratoplasty: full and partial-thickness cut wound strength and endothelial cell loss across a variety of wound patterns." British Journal of Ophthalmology 98, no. 7 (2014): 894–99. http://dx.doi.org/10.1136/bjophthalmol-2013-304546.

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42

Boyce, John M., Gail Potter-Bynoe, and Linda Dziobek. "Hospital Reimbursement Patterns among Patients with Surgical Wound Infections following Open Heart Surgery." Infection Control and Hospital Epidemiology 11, no. 2 (1990): 89–93. http://dx.doi.org/10.2307/30144267.

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43

Wagner, Glenn N., E. Don Stevens, and Philip Byrne. "Effects of Suture Type and Patterns on Surgical Wound Healing in Rainbow Trout." Transactions of the American Fisheries Society 129, no. 5 (2000): 1196–205. http://dx.doi.org/10.1577/1548-8659(2000)129<1196:eostap>2.0.co;2.

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44

Rousseau, J., D. Perreux, and N. Verdière. "The influence of winding patterns on the damage behaviour of filament-wound pipes." Composites Science and Technology 59, no. 9 (1999): 1439–49. http://dx.doi.org/10.1016/s0266-3538(98)00184-5.

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45

Gongal, D. N., B. M. Shrestha, V. L. Gurubacharya, and Jyotsana Shrestha. "Patterns of Post Operative Wound Infection and their Antibiotic Sensitivity in Bir Hospital." Journal of Nepal Medical Association 32, no. 112 (2003): 231–36. http://dx.doi.org/10.31729/jnma.1265.

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46

Gugatschka, Markus, Tsuyoshi Kojima, Satoshi Ohno, Shin-ichi Kanemaru, and Shigeru Hirano. "Recruitment patterns of side population cells during wound healing in rat vocal folds." Laryngoscope 121, no. 8 (2011): 1662–67. http://dx.doi.org/10.1002/lary.21817.

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47

Stanford, A. C., D. H. Northcote, and M. W. Bevan. "Spatial and temporal patterns of transcription of a wound-induced gene in potato." EMBO Journal 9, no. 3 (1990): 593–603. http://dx.doi.org/10.1002/j.1460-2075.1990.tb08151.x.

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48

Boyce, John M., Gail Potter-Bynoe, and Linda Dziobek. "Hospital Reimbursement Patterns among Patients with Surgical Wound Infections following Open Heart Surgery." Infection Control and Hospital Epidemiology 11, no. 2 (1990): 89–93. http://dx.doi.org/10.1086/646127.

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49

Tomic-Canic, Marjana, Elizabeth A. Ayello, Olivera Stojadinovic, Michael S. Golinko, and Harold Brem. "Using Gene Transcription Patterns (Bar Coding Scans) to Guide Wound Debridement and Healing." Advances in Skin & Wound Care 21, no. 10 (2008): 487–92. http://dx.doi.org/10.1097/01.asw.0000323563.59885.1c.

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50

Tomic-Canic, Marjana, Elizabeth A. Ayello, Olivera Stojadinovic, Michael S. Golinko, and Harold Brem. "Using Gene Transcription Patterns (Bar Coding Scans) to Guide Wound Debridement and Healing." Advances in Skin & Wound Care 21, no. 10 (2008): 493–94. http://dx.doi.org/10.1097/01.asw.0000323566.44638.28.

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