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1

Choi, Jeong Yeon, Yong-Joon Joo, Ri Jin Kang, Hee Kyung Jeon, and Gyeong Sik Hong. "Effect of Spray-Type Alginate Hydrogel Dressing on Burn Wounds." Gels 10, no. 2 (2024): 152. http://dx.doi.org/10.3390/gels10020152.

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Immediate burn wound care is a critical factor influencing the outcomes of burn treatment. In this study, we developed a spray-type alginate hydrogel dressing that promotes wound healing, reduces pain, and increases the convenience of use in a burn treatment emergency. We investigated the efficiency of newly developed spray-type alginate hydrogel dressing on the wound healing process. We investigated the efficacy of the alginate hydrogel dressing for wound healing in 30 Sprague Dawley rats. Four deep, round second-degree burn wounds (diameter, 1.5 cm) were created bilaterally on the dorsum of
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2

Díaz, G. A., B. A. Latorre, S. Jara, et al. "First Report of Diaporthe novem Causing Postharvest Rot of Kiwifruit During Controlled Atmosphere Storage in Chile." Plant Disease 98, no. 9 (2014): 1274. http://dx.doi.org/10.1094/pdis-02-14-0183-pdn.

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Chile is considered the third major exporter of kiwifruits (Actinidia deliciosa (A. Chev.) C. F. Liang & A. R. Ferguson) worldwide after Italy and New Zealand (1). The genus Diaporthe Nitschke (anamorph: genus Phomopsis) has been reported as causing postharvest rot in kiwifruit (4). During the current study, 1,400 fruits arbitrarily collected from seven controlled atmosphere (CA) rooms after 90 days of storage conditions (2% O2, 5% CO2) determined that 21.5% of the fruit were affected by decay and 0.86% developed symptoms different than those caused by Botrytis cinerea, the main postharves
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3

Udegbunam, Sunday O., Sunday Ogbobe, Nnamdi H. Okereke, Adaobi S. Enejere, Ijeoma R. Udegbunam, and Toochukwu H. Ezeobialu. "Assessment of wound contraction, re-epithelialization and histological changes in full thickness excision wounds of rats treated with different concentrations of hydrogen peroxide." Tropical Journal of Pharmaceutical Research 20, no. 8 (2022): 1623–29. http://dx.doi.org/10.4314/tjpr.v20i8.11.

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Purpose: To investigate the impact of treatment with different strengths of hydrogen peroxide (H2O2) on healing of excision-type wounds in rats.
 Methods: Thirty-two (n = 8) adult wistar rats randomly assigned to four groups A - D were used for the study. Full-thickness excision-type wound was surgically made on each rat on day 0. While wounds in group A, the control, were treated with 0.9 % normal saline, wounds in groups B - D received 1, 3, and 5 % H2O2, respectively. Following the surgical wounding and treatment, the epithelialization time, wound contraction, and histological changes
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4

Tang, Q. H., X. Q. Niu, F. Y. Yu, H. Zhu, W. W. Song, and W. Q. Qin. "First Report of Pindo Palm Heart Rot Caused by Ceratocystis paradoxa in China." Plant Disease 98, no. 9 (2014): 1282. http://dx.doi.org/10.1094/pdis-04-14-0395-pdn.

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On January 12th, 2012, a novel disease with an incidence of 50% was discovered in Pindo palm Butia capitata (Mart.) Becc from the Coconut Grant View Garden (19°33.137′ N, 110°47.482′ E) located in Wenchang, Hainan Province. Diseased leaflets at the base of the rotted heart leaves had reddish brown lesions; when the infection progressed, the leaves turned yellow and became blighted from the inner to the outer part of the crown. Once the growing point was destroyed, the entire tree ultimately died. Tissues from the edges of lesions from diseased leaflet samples were placed onto potato dextrose a
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5

Granata, G., R. Faedda, and A. Sidoti. "First Report of Canker Disease Caused by Diplodia olivarum on Carob Tree in Italy." Plant Disease 95, no. 6 (2011): 776. http://dx.doi.org/10.1094/pdis-12-10-0870.

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The evergreen carob tree (Ceratonia siliqua L., Fabaceae), also called locust, is widespread in the Mediterranean Region. Carob pods have been traditionally consumed as animal and human food and seeds are mainly used in the pharmaceutical and cosmetic industries. In July 2009, symptoms of canker, branch dieback, and foliage reddening were observed on carob trees in several natural areas in the province of Ragusa, Italy. Disease incidence ranged from 5 to 80% across different sites and for most areas it was nearly 15%. All affected trees showed dark necrotic tissue in the bark, cambium, and sap
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6

Shi, Z. R., M. M. Xiang, Y. X. Zhang, and J. H. Huang. "First Report of Leaf Spot on Gerbera jamesonii Caused by Corynespora cassiicola in China." Plant Disease 96, no. 6 (2012): 915. http://dx.doi.org/10.1094/pdis-12-11-1081-pdn.

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Gerbera (Gerbera jamesonii Bolus ex. Hook f.) is a popular cut flower and flowering potted plant. In August 2011, a new leaf spot disease was observed on double-type Gerbera growing in outdoor ground beds in Guangzhou, Guangdong Province, China. Approximately 30% of about 20,000 Gerbera plants in the Guangzhou ground beds were affected. Leaf spots were round or irregular with grayish centers surrounded by dark brown borders and ranged from 5 to 15 mm in diameter. Leaves with multiple lesions became blighted. A fungus was isolated from the lesions and single-spore isolates plated on potato dext
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7

Liao, Yanling, Munenari Itoh, Samantha Roberts, et al. "Human Umbilical Cord Blood (HUCB) Derived Pluripotent Stem Cells Enhances Wound Healing." Blood 118, no. 21 (2011): 4824. http://dx.doi.org/10.1182/blood.v118.21.4824.4824.

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Abstract Abstract 4824 Background: Recessive dystrophic epidermolysis bullosa (RDEB) is a severe inherited skin blistering disease caused by mutations in the type VII collagen (COL7A1) gene that encodes a major component in anchoring fibrils (Christiano et.al. Nat Gen 1993). Recently, iPSCs have been generated from RDEB patients, which provides promises on gene correction and future autologous Stem Cell Transplantation (SCT) (Itoh/Cairo/Christiano PNAS 2011). Currently, Allogeneic (Allo) SCT remains to be the best treatment for numerous malignant and non-malignant diseases in pediatric patient
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8

Olman, Mitchell A., James S. Hagood, Warren L. Simmons, Gerald M. Fuller, Charles Vinson, and Kimberly E. White. "Fibrin Fragment Induction of Plasminogen Activator Inhibitor Transcription Is Mediated by Activator Protein-1 Through a Highly Conserved Element." Blood 94, no. 6 (1999): 2029–38. http://dx.doi.org/10.1182/blood.v94.6.2029.

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Abstract Plasminogen activator inhibitor type-1 (PAI-1), a serine protease inhibitor, affects the processes of fibrinolysis, wound healing, and vascular remodeling. We have demonstrated that PAI-1 transcription is induced by D dimer, a plasmin proteolytic fragment of fibrin, supporting its role in negative feedback on peri-cellular proteolysis. The focus of this study was to define the mechanism of D dimer’s effects on PAI-1 transcription. D dimer increased the binding activity of the transcription factor activator protein-1 components c-fos/junD and c-fos mRNA levels in a time- and concentrat
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9

Olman, Mitchell A., James S. Hagood, Warren L. Simmons, Gerald M. Fuller, Charles Vinson, and Kimberly E. White. "Fibrin Fragment Induction of Plasminogen Activator Inhibitor Transcription Is Mediated by Activator Protein-1 Through a Highly Conserved Element." Blood 94, no. 6 (1999): 2029–38. http://dx.doi.org/10.1182/blood.v94.6.2029.418k25_2029_2038.

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Plasminogen activator inhibitor type-1 (PAI-1), a serine protease inhibitor, affects the processes of fibrinolysis, wound healing, and vascular remodeling. We have demonstrated that PAI-1 transcription is induced by D dimer, a plasmin proteolytic fragment of fibrin, supporting its role in negative feedback on peri-cellular proteolysis. The focus of this study was to define the mechanism of D dimer’s effects on PAI-1 transcription. D dimer increased the binding activity of the transcription factor activator protein-1 components c-fos/junD and c-fos mRNA levels in a time- and concentration-depen
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10

Raksha, Nataliia, Nataliia Nikitina, Liudmila Stepanova, and Tetayna Beregova. "COMPOSITIONS BASED ON COLLAGEN FROM HYDROBIONTS AS POTENTIAL WOUND HEALING AGENTS." Bulletin of Taras Shevchenko National University of Kyiv. Series: Biology 97, no. 2 (2024): 46–51. http://dx.doi.org/10.17721/1728.2748.2023.97.46-51.

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B a c k g r o u n d. The work was devoted to the study of compositions based on collagen extracted from hydrobionts as potential wound healing agents. The scales of Antarctic fish Champsocephalus gunnari, Nototheniidae and the biomass of jellyfish Diplulmaris antarctica were used as raw materials for obtaining collagen. M e t h o d s. To obtain collagen, the following steps were done: salting out non-collagen proteins with 10% NaCl, demineralization with 0.4 M HClO4, extraction of collagen with 0.5 M CH3COOH, reprecipitation of the obtained collagen with NaCl and CH3COOH, and lyophilization. R
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11

Etebarian, Hassan-Reza, Peter L. Sholberg, Kenneth C. Eastwell, and Ronald J. Sayler. "Biological control of apple blue mold withPseudomonas fluorescens." Canadian Journal of Microbiology 51, no. 7 (2005): 591–98. http://dx.doi.org/10.1139/w05-039.

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Pseudomonas fluorescens isolate 1100-6 was evaluated as a potential biological control agent for apple blue mold caused by Penicillium expansum or Penicillium solitum. Both the wild-type isolate 1100-6 and a genetically modified derivative labeled with the gene encoding the green fluorescent protein (GFP) were compared. The P. fluorescens isolates with or without GFP equally reduced the growth of Penicillium spp. and produced large zones of inhibition in dual culture plate assays. Cell-free metabolites produced by the bacterial antagonists reduced the colony area of Penicillium isolates by 17.
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12

Vargas, M., C. Loyola, N. Zapata, et al. "First Report of Root Rot of Chicory Caused by Phytophthora cryptogea in Chile." Plant Disease 96, no. 4 (2012): 591. http://dx.doi.org/10.1094/pdis-03-11-0245.

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Chicory (Cichorium intybus L. var sativum Bisch.), a relatively new high-value crop in Chile, was introduced for commercial production of inulin. Inulins are polysaccharides extracted from chicory tap roots that are used in processed foods because of their beneficial gastrointestinal properties. Approximately 3,000 ha of chicory are grown for local processing in the BioBio Region near Chillan in south central Chile. Recently, a severe rot of 1 to 3% of mature roots in the field and after harvest has been observed in most fields, which caused yield and quality losses. Typical symptoms include a
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13

Kjaer, Marie, Amalie Kruse Sigersted Frederiksen, Neel Ingemann Nissen, et al. "Multinutrient Supplementation Increases Collagen Synthesis during Early Wound Repair in a Randomized Controlled Trial in Patients with Inguinal Hernia." Journal of Nutrition 150, no. 4 (2020): 792–99. http://dx.doi.org/10.1093/jn/nxz324.

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ABSTRACT Background Inguinal hernia disease is associated with an imbalanced collagen metabolism. Surgical stress has a negative impact on nutrients important for collagen synthesis. Objective We hypothesized that supplementation with a combination of nutrients would enhance collagen biosynthesis in inguinal hernia disease patients when undergoing hernia repair. Methods In this exploratory randomized controlled trial, 21 men (age: 55.2 ± 2.8 y; BMI: 25.0 ± 0.7 kg/m2) scheduled for Lichtenstein inguinal hernia repair were assigned to multinutrient supplementation (n = 10; multinutrient group) o
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14

Palou, L., V. Taberner, and C. Montesinos-Herrero. "First Report of Diplodia seriata Causing Loquat Fruit Rot in Spain." Plant Disease 97, no. 3 (2013): 421. http://dx.doi.org/10.1094/pdis-08-12-0728-pdn.

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Spain is the second largest loquat (Eriobotrya japonica Lindl.) producer in the world, with about 40,000 t per year. ‘Algerie’ is the main cultivar planted in Alicante province (SE of Spain; Lat. 38.40° N, Long. 0.08° W), where more than 80% of Spanish commercial loquat plantations are located. In a survey of fruit losses at harvest, irregular brownish superficial dry spots (5 to 15 mm) located mainly near the stem end were observed on fruits from different orchards. After incubation at 20°C for 14 days, the spots on fruit expanded rapidly and turned to dark brown or black, producing black, un
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15

Artemenko, V.O., M.M. Matsipura, and S.O. Sazonova. "Non-interventional study of the epidemiological and clinical aspects of war-related spinal cord injuries among military personnel." Medicni perspektivi 30, no. 1 (2025): 78–89. https://doi.org/10.26641/2307-0404.2025.1.325361.

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With the beginning of active hostilities in Ukraine the amount of victims with gunshot, mine-explosive and shrapnel injuries of the musculoskeletal system among  military personnel increased sharply. Therefore, the problems of treatment and rehabilitation of victims of hostilities have become especially acute in the last year. The purpose of the study was to characterize combat spinal cord injuries in military personnel based on the analyzed literature and clinical observations based on medical institutions. Primary literature search was conducted using Medline, Excerpta Medica dataBASE,
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16

Shah, Maria, Farkhunda Nadeem, Raima Kalhoro, Safiya Javed, Bushra Sajid, and Kiran Irfan. "HISTOPATHOLOGICAL EVALUATION OF EFFECTS OF CURCUMIN AND ALOE VERA GEL ON CUTANEOUS WOUND HEALING IN ALBINO WISTAR RATS." Pakistan Journal of Physiology 20, no. 4 (2024): 13–16. https://doi.org/10.69656/pjp.v20i4.1652.

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Background: Healing is a survival process and essential for maintaining normal anatomical structure and function. Curcumin, the primary active compound in turmeric, and aloe vera, possess notable antioxidant and antimicrobial properties which aid in healing. Objective of this study was to investigate the effects of curcumin and aloe vera on cutaneous wound healing. Methods: This experimental study was conducted in Department of Pathology, Isra University, Hyderabad, from January to July 2023. Sixty-four healthy albino Wistar rats weighing 150–250 grams were procured from Sindh Agriculture Univ
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17

Varela, C. Pintos, V. Redondo Fernández, O. Aguín Casal, and J. P. Mansilla Vázquez. "First Report of Cankers and Dieback Caused by Neofusicoccum mediterraneum and Diplodia corticola on Grapevine in Spain." Plant Disease 95, no. 10 (2011): 1315. http://dx.doi.org/10.1094/pdis-05-11-0429.

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In November 2010, four grapevine plants of cv. Crimson from a vineyard located in Sevilla (south Spain) revealed trunk cankers. Several pathogens were isolated, including Cylindrocarpon liriodendri (2), Phaeoacremonium aleophilum (2), Pleurostomophora richardsiae, Neofusicoccum parvum, and Botryosphaeria dothidea (2). Among Botryosphaeriaceae fungi isolated on potato dextrose agar (PDA) were two types that did not fit the above mentioned species. Isolates of type 1 produced an abundant, gray mycelium with a diurnal zonation that gradually became dark olivaceous. Mycelium growth occurred from 5
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18

Kono, T., T. Tanii, M. Furukawa, et al. "Correlation between ageing and collagen gel contractility of human fibroblasts." Acta Dermato-Venereologica 70, no. 3 (1990): 241–44. http://dx.doi.org/10.2340/0001555570241244.

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To investigate the influence of ageing on wound healing, we cultured fibroblasts derived from human dermis in type I collagen gel, and evaluated the relationship between gel contractility and ageing. Cells were obtained from children (0-15 years old, Group A), early adulthood (16-40 years old, Group B), mid-adulthood (41-60 years old, Group C), and the elderly (61 or older, Group D). Gel contractility was determined by measuring the diameter on the second day after gel preparation. Within the tenth passage, gel contraction was the most marked in Group A, but did not differ among the other grou
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19

Afarideh, Mohsen, Parvaneh Ghanbari, Sina Noshad, Alireza Ghajar, Manouchehr Nakhjavani, and Alireza Esteghamati. "Raised serum 25-hydroxyvitamin D levels in patients with active diabetic foot ulcers." British Journal of Nutrition 115, no. 11 (2016): 1938–46. http://dx.doi.org/10.1017/s0007114516001094.

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AbstractStudies have emerged to demonstrate bidirectional changes in circulating cytokines of inflammation in active diabetic foot ulcers (DFU). To further expand the understanding of inflammatory status present in chronic active DFU, we comparatively assessed the associations of selected pro-inflammatory cytokines and 25-hydroxyvitamin D (25(OH)D) with the presence of DFU. In a cross-sectional setting, thirty patients with type 2 diabetes and active DFU matched with thirty control non-ulcerative patients with type 2 diabetes and twenty-eight healthy subjects underwent anthropometric and bioch
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20

Safani, Erra Ericha, Wanodya Ayu Chandradevi Kunharjito, Alfiyan Lestari, and Erlix Rakhmad Purnama. "Potensi Ekstrak Daun Bandotan (Ageratum conyzoides L.) Sebagai Spray Untuk Pemulihan Luka Mencit Diabetik Yang Terinfeksi Staphylococcus aureus." Biotropic : The Journal of Tropical Biology 3, no. 1 (2019): 68–78. http://dx.doi.org/10.29080/biotropic.2019.3.1.68-78.

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Ageratum conyzoides L. leaf has the main compound of flavonoids and alkaloids that contribute to accelerate the healing process of diabetic ulcers with Staphylococcus aureus infection that can affect the quality of life of patients. This study aims to test the leaves of Ageratum conyzoides L. on the recovery of diabetic ulcers of mice infected with Staphylococcus aureus. The method used is the extraction of Ageratum conyzoides L leaves as the material of spray 15%, induction of diabetic compound (Alloxan monohydrate), length wound (1cm) and bacterial infections, and spray application with 1 ti
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21

Tarnowski, T. L. B., and R. C. Ploetz. "First Report of Colletotrichum capsici Causing Postharvest Anthracnose on Papaya in South Florida." Plant Disease 94, no. 8 (2010): 1065. http://dx.doi.org/10.1094/pdis-94-8-1065b.

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Postharvest anthracnose of papaya, Carica papaya, is an important disease in most production areas worldwide (2). Colletotrichum gloeosporioides causes two types of anthracnose symptoms on papaya: (i) circular, sunken lesions with pink sporulation; and (ii) sharply defined, reddish brown and sunken lesions, described as ‘chocolate spot’ (2). Colletorichum spp. were isolated from lesions of the first type on papaya fruit from the University of Florida Tropical Research and Education Center, Homestead in December 2007 and from fruit imported from Belize in March 2008 (4). Single-spore isolates w
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22

Friedmann, Anton, Stefan Fickl, Kai R. Fischer, Milad Dalloul, Werner Goetz, and Frederic Kauffmann. "Horizontal Augmentation of Chronic Mandibular Defects by the Guided Bone Regeneration Approach: A Randomized Study in Dogs." Materials 15, no. 1 (2021): 238. http://dx.doi.org/10.3390/ma15010238.

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Various biomaterial combinations have been studied focusing on their ability to stabilize blood clots and maintain space under soft tissue to support new bone formation. A popular combination is Deproteinized Bovine Bone Mineral (DBBM) placed with a native collagen membrane (NCM) tacked to native bone. In this study, we compared the outcome of this treatment option to those achieved with three different graft/membrane combinations with respect to total newly occupied area and the mineralized compound inside. After bi-lateral extraction of two mandibular premolars in five adult beagles L-shaped
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23

Artemenko, V. O., M. M. Matsipura, and S. O. Sazonova. "Non-interventional study of the epidemiological and clinical aspects of war-related spinal cord injuries among military personnel." Medicni perspektivi 30, no. 1 (2025): 78–89. https://doi.org/10.26641/2307-0404.2025.1.325361.

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With the beginning of active hostilities in Ukraine the amount of victims with gunshot, mine-explosive and shrapnel injuries of the musculoskeletal system among military personnel increased sharply. Therefore, the problems of treatment and rehabilitation of victims of hostilities have become especially acute in the last year. The purpose of the study was to characterize combat spinal cord injuries in military personnel based on the analyzed literature and clinical observations based on medical institutions. Primary literature search was conducted using Medline, Excerpta Medica dataBASE, and Ps
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24

Khalyfa, Abdelnaby, David Gozal, and Leila Kheirandish-Gozal. "Plasma Extracellular Vesicles in Children with OSA Disrupt Blood–Brain Barrier Integrity and Endothelial Cell Wound Healing In Vitro." International Journal of Molecular Sciences 20, no. 24 (2019): 6233. http://dx.doi.org/10.3390/ijms20246233.

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Pediatric obstructive sleep apnea (P-OSA) is associated with neurocognitive deficits and endothelial dysfunction, suggesting the possibility that disruption of the blood–brain barrier (BBB) may underlie these morbidities. Extracellular vesicles (EVs), which include exosomes, are small particles involved in cell–cell communications via different mechanisms and could play a role in OSA-associated end-organ injury. To examine the roles of EVs in BBB dysfunction, we recruited three groups of children: (a) absence of OSA or cognitive deficits (CL, n = 6), (b) OSA but no evidence of cognitive defici
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25

Carvalho, Isabel S., Cláudia Viegas, Marta Markiewicz, et al. "Plant-Based Potential in Diabetes Management: In Vitro Antioxidant, Wound-Healing, and Enzyme Inhibitory Activities of Southern Algarve Species." Molecules 30, no. 11 (2025): 2432. https://doi.org/10.3390/molecules30112432.

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Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by impaired glucose regulation. This study evaluated the antioxidant and antidiabetic potential of aqueous extracts from four plant species from the southern Algarve: Aristolochia baetica, Chelidonium majus, Dittrichia viscosa, and Lavandula viridis, using non-cellular in vitro assays. HPLC/PDA was used to identify active compounds. Antioxidant activity was assessed by using TAA, FRAP, RP, and DPPH assays; antidiabetic potential through α-glucosidase and α-amylase inhibition; and wound healing relevance through elast
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26

Islam, Md Ariful, Ho Jin Choi, Raju Dash, et al. "N-Acetyl-d-Glucosamine Kinase Interacts with NudC and Lis1 in Dynein Motor Complex and Promotes Cell Migration." International Journal of Molecular Sciences 22, no. 1 (2020): 129. http://dx.doi.org/10.3390/ijms22010129.

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Recently, we showed that N-acetylglucosamine kinase (NAGK), an enzyme of amino sugar metabolism, interacts with dynein light chain roadblock type 1 (DYNLRB1) and promotes the functions of dynein motor. Here, we report that NAGK interacts with nuclear distribution protein C (NudC) and lissencephaly 1 (Lis1) in the dynein complex. Yeast two-hybrid assays, pull-down assays, immunocytochemistry, and proximity ligation assays revealed NAGK–NudC–Lis1–dynein complexes around nuclei, at the leading poles of migrating HEK293T cells, and at the tips of migratory processes of cultured rat neuroblast cell
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27

Valencia, A. L., R. A. Chorbadjian, and B. A. Latorre. "First Report of Nothofagus macrocarpa Dieback Caused by Phytophthora citrophthora and P. nicotianae in Chile." Plant Disease 95, no. 9 (2011): 1193. http://dx.doi.org/10.1094/pdis-03-11-0258.

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The genus Nothofagus, family Nothofagaceae, comprises 36 species of trees that are native to the Southern Hemisphere. N. macrocarpa (DC.) F.M. Vásquez & R.A. Rodríguez (Roble de Santiago) is an important deciduous tree, endemic to central Chile (32 to 35°S), and found above 800 m altitude. There is an increasing interest in N. macrocarpa as an ornamental. However, a general dieback (40 to 50% prevalence) was observed at a commercial nursery in Santiago in 2009, limiting its multiplication. Symptoms are wilting, partial defoliation, reddish brown cankers on the crowns, and root necrosis. Th
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28

Owen, Donald R., David L. Wood, and John R. Parmeter. "Association between Dendroctonus valens and black stain root disease on ponderosa pine in the Sierra Nevada of California." Canadian Entomologist 137, no. 3 (2005): 367–75. http://dx.doi.org/10.4039/n04-084.

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AbstractThe host-colonization behavior of the red turpentine beetle, Dendroctonus valens LeConte (Coleoptera: Scolytidae), was investigated in stands of ponderosa pine, Pinus ponderosa P. & C. Lawson (Pinaceae), with black stain root disease in the central Sierra Nevada of California. By felling live trees, we found that trees with pitch tubes produced during the initiation of tunneling by D. valens had a significantly higher incidence of black stain root disease, caused by Leptographium wageneri var. ponderosum (Harrington et Cobb), than trees without pitch tubes. Trees with the most D. v
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29

González-Serrano, José, Julia Serrano, Rosa María López-Pintor, Víctor Manuel Paredes, Elisabeth Casañas, and Gonzalo Hernández. "Prevalence of Oral Mucosal Disorders in Diabetes Mellitus Patients Compared with a Control Group." Journal of Diabetes Research 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/5048967.

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Chronic hyperglycemia is associated with impaired wound healing and higher susceptibility to infections. It is unclear whether patients with diabetes mellitus (DM) present more oral mucosal disorders compared to control groups. The objectives were to compare (a) the prevalence rates of oral mucosal disorders in the DM and non-DM population and (b) the prevalence rates of specific disorders in the DM and non-DM population. Full-text articles were included if they met the following inclusion criteria: (a) they must be original articles from scientific journals, (b) they must be only cross-sectio
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30

Vettraino, A. M., D. Hüberli, S. Swain, J. C. Bienapfl, A. Smith, and M. Garbelotto. "First Report of Infection of Maiden-Hair Fern (Adiantum jordanii and A. aleuticum) by Phytophthora ramorum in California." Plant Disease 90, no. 3 (2006): 379. http://dx.doi.org/10.1094/pd-90-0379b.

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During July 2005, Phytophthora ramorum S. Werres & A.W.A.M. de Cock was isolated from nine native Adiantum jordanii plants growing at two forest sites (Samuel P. Taylor State Park, Marin County and Peachland Road, Mendocino County) and from seven A. aleuticum plants at one forest site (Peachland Road) in California. At both locations, symptomatic plants were distributed close to rivers and roads and in association with infected bay laurel trees (Umbellularia californica), toyon (Heteromeles arbutifolia), and tanoaks (Lithocarpus densiflorus). Symptomatic leaflets showed brown spots that so
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Žulec, Mirna, Danica Rotar-Pavlič, Zrinka Puharić, and Ana Žulec. "“Wounds Home Alone”—Why and How Venous Leg Ulcer Patients Self-Treat Their Ulcer: A Qualitative Content Study." International Journal of Environmental Research and Public Health 16, no. 4 (2019): 559. http://dx.doi.org/10.3390/ijerph16040559.

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Background: Venous leg ulcers (VLUs), the most common type of leg ulcerations, have long healing times and high recurrence rates; reimbursement rules and a general shortage of nursing staff have put self-treatment into focus. The study aimed to investigate why and how patients with VLUs self-treat their ulcers. Methods: Patients with VLUs (N = 32) were selected by criterion sampling for a multicentric qualitative study using semi-structured interviews. The interviews were analyzed via inductive qualitative content analysis. Results: More than two-thirds of participants sometimes self-treated V
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Li, Li, Xuemei He, Jian Sun, et al. "Responses of Phospholipase D and Antioxidant System to Mechanical Wounding in Postharvest Banana Fruits." Journal of Food Quality 2017 (2017): 1–8. http://dx.doi.org/10.1155/2017/8347306.

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Banana fruits are susceptible to mechanical damage. The present study was to investigate the responses of phospholipase D (PLD) and antioxidant system to mechanical wounding in postharvest banana fruits. During 16 d storage at 25°C and 90% relative humidity, PLD activity in wounded fruits was significantly higher than that in control (without artificial wounding fruits). The higher value of PLD mRNA was found in wounded fruits than in control. PLD mRNA expression reached the highest peak on day 4 in both groups, but it was 2.67 times in wounded fruits compared to control at that time, indicati
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Elhabal, Sammar Fathy, Ahmed Mohsen Faheem, Sandra Hababeh, et al. "Augmented Marshmallow Extract Lipid Nanoparticles with Clove Oil Embedded in Collagen Sponge for Ultimate Antimicrobial Healing of Diabetic Mouth Ulcer." Pharmaceutics 17, no. 5 (2025): 611. https://doi.org/10.3390/pharmaceutics17050611.

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Background/Objectives: Diabetic mouth ulcers are a pathological condition of the oral mucosa leading to increases in susceptibility to infection and prolonged wound healing time. Still, there is a lack of natural formulations for treating this condition. Our principal objective was to formulate solid lipid nanoparticles (SLNs) that contained Althaea officinalis (marshmallow) (M.) extract with clove oil (CO.), subsequently integrated into a collagen sponge for enhancing stability, solubility, sustained release, antimicrobial efficacy, and healing power when targeting diabetic oral ulcers. Metho
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34

Marina Silalahi. "Potential utilization of purslane (Portulaca oleracea L.) as food ingredients and traditional medicine." International Journal of Frontiers in Biology and Pharmacy Research 3, no. 2 (2022): 001–7. http://dx.doi.org/10.53294/ijfbpr.2022.3.2.0059.

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Portulaca oleracea (PO) is a type of wild plant that has long been used as food and traditional medicine. This study aims to examine the use of PO as a food ingredient and traditional medicine and its bioactivity. The research method is a literature study on various online scientific sources from Google scholar using the keywords PO and uses PO. The information obtained is synthesized so that it can explain the use of PO in a comprehensive manner. Purslane is a nutritious vegetable with high antioxidant properties and has been recognized as the richest source of a-linolenic acid, omega-3 fatty
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35

Onah, J. A. ,., S. T. Fadason, E. Abidoye, K. B. Kadima, and S. E. Abalaka. "Histopathological Alterations in Cutaneous Wound Healing and Pancreatic Architecture in Alloxan-Induced Diabetic Rabbits." Journal of Veterinary and Biomedical Sciences 6, no. 2 (2024): 42–59. https://doi.org/10.36108/jvbs/4202.60.0260.

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The study evaluated the pancreatic cellular responses and histopathological changes associated with the cutaneous wound healing g of alloxan induced diabetic New Zealand White (NZW). Sixteen adult rabbits of either sex, weighing 1.8 – 3.2 kg were used for the study. They were divided into four group. s Group A is the control, it was -non diabetic and no wound. Group B was diabetic and no wound, whereas group C was non-diabetic and with wounded while group D was having wounded and diabetic. Diabetes induction was accomplished by administration of 100 mg/kg of alloxan monohydrate twice, 72 h apa
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M., Naveen Kumar, and Virender Kolagani. "EVALUATION OF NOOTROPIC ACTIVITY OF CARICA PAPAYA IN MICE." Biolife 2, no. 3 (2022): 721–30. https://doi.org/10.5281/zenodo.7219751.

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<strong>ABSTRACT</strong> Alzheimer&rsquo;s disease is a progressive neurodegenerative disorder primarily manifesting as a loss of memory, senile dementia, and intraneuronal neurofibrillary tangle formation. <em>C. papaya</em> has a very long history of medicinal use in Chinese and Indian herbal traditions. The objective of this study is to evaluate the nootropic activity of Carica papaya by using animal model mice. The dried seeds of papaya fruits were used for the extraction by cold maceration method using ethanol as solvent. Preliminary Phytochemical study was performed. Estimation of anti-
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Beaty, Narlin, Justin Slavin, Cara Diaz, Kyle Zeleznick, David Ibrahimi, and Charles A. Sansur. "Cervical spine injury from gunshot wounds." Journal of Neurosurgery: Spine 21, no. 3 (2014): 442–49. http://dx.doi.org/10.3171/2014.5.spine13522.

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Object Gunshot wounds (GSWs) to the cervical spine have been examined in a limited number of case series, and operative management of this traumatic disease has been sparsely discussed. The current literature supports and the authors hypothesize that patients without neurological deficit need neither surgical fusion nor decompression. Patients with GSWs and neurological deficits, however, pose a greater management challenge. The authors have compiled the experience of the R Adams Cowley Shock Trauma Center in Baltimore, Maryland, over the past 12 years, creating the largest series of such inju
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Venard, C., and L. Vaillancourt. "Colonization of Fiber Cells by Colletotrichum graminicola in Wounded Maize Stalks." Phytopathology® 97, no. 4 (2007): 438–47. http://dx.doi.org/10.1094/phyto-97-4-0438.

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Colonization of wounded maize stalks by a wild-type strain of Colletotrichum graminicola was compared with colonization by a C. graminicola mutant that is avirulent on maize leaves, and by a wild-type strain of C. sublineolum that is normally a pathogen of sorghum but not maize. Local infection by all strains at the wound site resulted in formation of primary lesions consisting of disintegrated parenchyma cells beneath an intact rind and epidermis. However, subsequent rapid longitudinal expansion of the primary lesion occurred only in infections with the wild-type C. graminicola strain, and pr
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Siddique, Muhammad Khalid, Waqas Ahmed, Khalid Pervaiz Butt, Khalid Ibrahim Akhtar, Hamna Khalid, and Muhammad Tariq Khan. "The PRESENTATION AND OUTCOMES OF AORTOFEMORAL BYPASS SURGERY IN PATIENTS WITH AORTOILIAC OCCLUSIVE DISEASE. FOUR YEARS’ EXPERIENCE AT A TERTIARY CARE HOSPITAL." Pakistan Armed Forces Medical Journal 70, no. 6 (2020): 1696–701. http://dx.doi.org/10.51253/pafmj.v70i6.4425.

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Objective: To highlight the presentation and outcomes of Aortofemoral bypass surgery at a tertiary care hospital.&#x0D; Study Design: Prospective observational study.&#x0D; Place and Duration of Study: Vascular Surgery department, Combined Military Hospital Lahore, from Jan 2015to Dec 2019.&#x0D; Methodology: A total of 23 patients between 50-80 years of age presenting with critical limb ischemia due toAortoiliac occlusive arterial disease type C or D of Trans-Atlantic inter Society Consensus (TASC) II classificationconfirmed on CT Angiogram, were included in the study. The clinical presentati
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Basankin, I. V., A. A. Giulzatyan, A. A. Afaunov, et al. "Experience in surgical treatment of patients with traumatic spinal injuries associated with ankylosing spondylitis." Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika) 21, no. 2 (2024): 6–12. http://dx.doi.org/10.14531/ss2024.2.6-12.

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Objective. To analyze characteristics, diagnostic features and results of surgical treatment of patients with traumatic spinal injuries associated with ankylosing spondylitis.Material and Methods. A retrospective analysis of the results of surgical treatment of 32 patients (25 men and 7 women) operated on in 2019–2022 was performed. Results were followed-up during 12 months in all patients. Patient characteristics, diagnostic features,clinical outcomes, and the range of postoperative complications were reviewed.Results. The number of damaged levels in the cervical, thoracic and lumbar spine wa
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Moral, Juan, Concepción Muñoz-Díez, Nazaret González, Antonio Trapero, and Themis J. Michailides. "Characterization and Pathogenicity of Botryosphaeriaceae Species Collected from Olive and Other Hosts in Spain and California." Phytopathology® 100, no. 12 (2010): 1340–51. http://dx.doi.org/10.1094/phyto-12-09-0343.

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Species in the family Botryosphaeriaceae are common pathogens causing fruit rot and dieback of many woody plants. In this study, 150 Botryosphaeriaceae isolates were collected from olive and other hosts in Spain and California. Representative isolates of each type were characterized based on morphological features and comparisons of DNA sequence data of three regions: internal transcribed spacer 5.8S, β-tubulin, and elongation factor. Three main species were identified as Neofusicoccum mediterraneum, causing dieback of branches of olive and pistachio; Diplodia seriata, causing decay of ripe fr
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42

Janisiewicz, W. J., T. J. Tworkoski, and C. P. Kurtzman. "Biocontrol Potential of Metchnikowia pulcherrima Strains Against Blue Mold of Apple." Phytopathology® 91, no. 11 (2001): 1098–108. http://dx.doi.org/10.1094/phyto.2001.91.11.1098.

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Eight strains of Metschnikowia pulcherrima isolated over a 4-year period from an unmanaged orchard and selected for their biocontrol activity against blue mold (caused by Penicillium expansum) of apples were characterized phenotypically, genetically, and for their biocontrol potential against blue mold on apples. All strains grew well and only differed slightly in their growth in nutrient yeast dextrose broth medium at 1°C after 216 h, but large differences occurred at 0°C, with strain T5-A2 outgrowing other strains by more than 25% transmittance after 360 h. This strain was also one of the mo
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43

Bischoff, Werner E., Tammy M. Reynolds, Gaye O. Hall, Richard P. Wenzel, and Michael B. Edmond. "Molecular Epidemiology of Vancomycin-ResistantEnterococcus faecium in a Large Urban Hospital over a 5-Year Period." Journal of Clinical Microbiology 37, no. 12 (1999): 3912–16. http://dx.doi.org/10.1128/jcm.37.12.3912-3916.1999.

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To investigate the dissemination of vancomycin-resistantEnterococcus faecium (VREF) in a 728-bed tertiary-care hospital, all clinical VREF isolates recovered from June 1992 to June 1997 were typed by pulsed-field gel electrophoresis, and the transfer histories of the patients were documented. A total of 413 VREF isolates from urine (52%), wounds (16%), blood (11%), catheter tips (6%), and other sites (15%) were studied. VREF specimens mostly came from patients on wards (66%) but 34% came from patients in an intensive care unit. The number of VREF isolates progressively increased over time, wit
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44

Zhen, Wenna, Yi Tu, Zihan Lin, Xinxin Xu, Maorun Fu, and Cong Han. "Comparative Transcriptome Analysis Reveals the Molecular Mechanism of UV-B Irradiation in Promoting the Accumulation of Phenolic Compounds in Wounded Carrot." Horticulturae 8, no. 10 (2022): 896. http://dx.doi.org/10.3390/horticulturae8100896.

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Ultraviolet B (UV-B) irradiation has been demonstrated to play a synergistic effect with wounding in enhancing the accumulation of phenolic antioxidants in carrots. However, little is known about the molecular mechanisms of UV-B treatment on wounded carrots. In this study, wounded carrots were exposed to different doses of UV-B light, then stored at 15 °C for 2 d. The results showed that the content of phenolic compounds in 1 KJ m−2 UV-B–treated samples was 415% and 247% higher than that of whole and wounded carrots, respectively. Based on this, 1 KJ m−2 was selected as the optimal dose of UV-
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45

Schor, S. L., I. Ellis, C. Dolman, et al. "Substratum-dependent stimulation of fibroblast migration by the gelatin-binding domain of fibronectin." Journal of Cell Science 109, no. 10 (1996): 2581–90. http://dx.doi.org/10.1242/jcs.109.10.2581.

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Nanomolar concentrations of native fibronectin and its RGDS-containing cell-binding domain have previously been reported to stimulate fibroblast migration in the transmembrane (or ‘Boyden chamber’) assay; in contrast, the gelatin-binding domain (GBD) of fibronectin has consistently been reported to be devoid of migration-stimulating activity in this assay. We have examined the effects of fibronectin and several of its purified functional domains on the migration of human skin fibroblasts in what is presumably a more physiologically relevant assay involving the movement of cells into a 3-D matr
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46

Billones, R. G., H. J. Ridgway, E. E. Jones, and M. V. Jaspers. "First Report of Neofusicoccum macroclavatum as a Canker Pathogen of Grapevine in New Zealand." Plant Disease 94, no. 12 (2010): 1504. http://dx.doi.org/10.1094/pdis-07-10-0494.

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In a 2008 survey, 120 isolates of the Botryosphaeriaceae were recovered from a representative subsample of Vitis vinifera plants and propagation materials collected in nine New Zealand grapevine nurseries. Isolates were identified by amplified ribosomal DNA restriction analysis (ARDRA) (1) as Neofusicoccum luteum (56%), N. parvum (18%), N. australe (8%), Diplodia mutila (7%), Botryosphaeria dothidea (5%), D. seriata (3%), and N. ribis (2%). One isolate (M353) from 1 cm below the graft union of a nonsymptomatic 1-year-old grafted plant from the Nelson Region was not identified by ARDRA and was
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Berbert, Mariana, Sicilia Arruda, Camila Bichuetti, et al. "Treatment of Diabetic Wounds With Photodynamic Therapy - Preliminary Results." Journal of the Endocrine Society 5, Supplement_1 (2021): A422. http://dx.doi.org/10.1210/jendso/bvab048.861.

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Abstract Diabetic patients have greater susceptibility to developing diabetic foot ulcers (DFU), which associated with peripheral arterial disease and/or infection, causes greater difficulty in the healing process. Photodynamic therapy (PDT) presents itself as a promising alternative for ulcer healing. This study aims to analyze the effectiveness and benefits of PDT in the treatment of diabetic wounds, associating the presence of arteriopathy, the size of the lesion, the presence and type of infection and the need for amputation. After the approval of the ethics committee in research and signi
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48

Freitas, R. L., E. Maciel-Zambolim, L. Zambolim, et al. "Colletotrichum boninense Causing Anthracnose on Coffee Trees in Brazil." Plant Disease 97, no. 9 (2013): 1255. http://dx.doi.org/10.1094/pdis-03-13-0229-pdn.

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In Brazil, dieback and necrosis of leaves and berries of coffee trees (Coffea arabica and C. canephora) are common symptoms of anthracnose disease caused by Colletotrichum gloeosporioides (Penz.) Sacc. In April 2010, these symptoms were observed in 100% of the plants from different coffee plantations in the Brazilian states of Espírito Santo and Bahia. Ten isolates were obtained from symptomatic leaves and berries from these areas. Of the 10 isolates, one had distinct conidial morphology with hyaline and ellipsoid conidia measuring 10 to 16 × 5.0 to 7.5 μm and melanized irregular or spatulated
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Bradley, C. A., P. S. Parks, Y. Chen, and W. G. D. Fernando. "First Report of Pathogenicity Groups 3 and 4 of Leptosphaeria maculans on Canola in North Dakota." Plant Disease 89, no. 7 (2005): 776. http://dx.doi.org/10.1094/pd-89-0776c.

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Blackleg, caused by Leptosphaeria maculans (Desmaz) Ces. &amp; de Not (anamorph = Phoma lingam), is an economically important disease of canola (Brassica napus L.) worldwide and was first detected in North Dakota in 1991 (3). L. maculans can be categorized into one of several pathogenicity groups (PGs) on the basis of the interaction phenotypes in differential canola cvs. Westar, Glacier, and Quinta by using a standard screening protocol in the greenhouse (4). With this system, PG1 strains are weakly virulent and PG2, PG3, and PG4 are highly virulent. The predominant strains of L. maculans in
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Bobev, S. G., K. Van Poucke, and M. Maes. "First Report of Phytophthora citricola on Cornus mas in Bulgaria." Plant Disease 93, no. 5 (2009): 551. http://dx.doi.org/10.1094/pdis-93-5-0551a.

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Cornelian cherry dogwood (Cornus mas) is a widespread species in Bulgaria and some cultivars with large fruits are the subject of propagation. In the springs of 2007 and 2008, severe, unusual damages were observed on sporadically scattered plantlets of ‘Kazanlashki’ (known also as ‘Kazanlaker’) in a nursery located near Vratza in northwestern Bulgaria. Symptoms were identical in both years and expressed on the leaves, young shoots, and adjacent rootstock wood. Dark brown, necrotic leaf spots initiated most often from the leaf periphery and quickly covered more than half of the leaf area. Necro
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