Relevant bibliographies by topics / Wyeth

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Reports

Academic literature on the topic 'Wyeth'

Author: Grafiati
Published: 4 June 2021
Last updated: 3 March 2023

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Journal articles on the topic "Wyeth"

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Mac Giolla Léith, Caoimhín. "Welling's Wyeth." Afterall: A Journal of Art, Context and Enquiry 32 (March 2013): 20–31. http://dx.doi.org/10.1086/670178.

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Cruz, Nádia Vaez G., Matheus Nobrega Luques, Terezinha Marta Pereira P. Castiñeiras, Orlando Costa Ferreira Jr, Regina Helena S. Peralta, Luciana J. da Costa, and Clarissa R. Damaso. "Genomic Characterization of the Historical Smallpox Vaccine Strain Wyeth Isolated from a 1971 Seed Vial." Viruses 15, no. 1 (December 28, 2022): 83. http://dx.doi.org/10.3390/v15010083.

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The Wyeth strain of vaccinia virus (VACV) produced by Wyeth Pharmaceuticals was supposedly used to manufacture the old freeze-dried American smallpox vaccine, Dryvax, until its discontinuation in 2008. Although the genomic sequences of numerous Dryvax clones have been reported, data on VACV-Wyeth genomes are still lacking. Genomic analysis of old VACV strains is relevant to understand the evolutionary relationships of smallpox vaccines, particularly with the recent resumption of smallpox vaccination in certain population groups as an attempt to control the worldwide monkeypox outbreak. Here we analyzed the complete genome sequences of three VACV-Wyeth clonal isolates obtained from a single seed vial donated to the Brazilian eradication program in the 1970s. Wyeth clones show >99.3% similarity to each other and >95.3% similarity with Dryvax clones, mapping together in clade I of the vaccinia group. Although the patterns of SNPs and INDELs comparing Dryvax and Wyeth clones are overall uniform, important differences were detected particularly at the ends of the genome. In addition, we detected recombinant events of clone Wyeth A111 and the Dryvax clone Acam2000, suggesting that other regions of the genomes may have similar patchy patterns of recombination. A small-scale serological survey using VACV-Wyeth as antigen in ELISA assays revealed that 63 of the 65 individuals born before the end of smallpox vaccination in Brazil still have anti-VACV IgG antibodies, demonstrating the usefulness of the VACV-Wyeth strain in future extended serological studies of the Brazilian population.
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JARVIS, LISA. "PFIZER BUYS WYETH." Chemical & Engineering News 87, no. 5 (February 2, 2009): 7. http://dx.doi.org/10.1021/cen-v087n005.p007.

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Perera, Liyanage P., Thomas A. Waldmann, Joseph D. Mosca, Nicole Baldwin, Jay A. Berzofsky, and Sang-Kon Oh. "Development of Smallpox Vaccine Candidates with Integrated Interleukin-15 That Demonstrate Superior Immunogenicity, Efficacy, and Safety in Mice." Journal of Virology 81, no. 16 (June 6, 2007): 8774–83. http://dx.doi.org/10.1128/jvi.00538-07.

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ABSTRACT The potential use of variola virus, the etiological agent of smallpox, as a bioterror agent has heightened the interest in the reinitiation of smallpox vaccination. However, the currently licensed Dryvax vaccine, despite its documented efficacy in eradicating smallpox, is not optimal for the vaccination of contemporary populations with large numbers of individuals with immunodeficiencies because of severe adverse effects that can occur in such individuals. Therefore, the development of safer smallpox vaccines that can match the immunogenicity and efficacy of Dryvax for the vaccination of contemporary populations remains a priority. Using the Wyeth strain of vaccinia virus derived from the Dryvax vaccine, we generated a recombinant Wyeth interleukin-15 (IL-15) with integrated IL-15, a cytokine with potent immunostimulatory functions. The integration of IL-15 into the Wyeth strain resulted in a >1,000-fold reduction in lethality of vaccinated athymic nude mice and induced severalfold-higher cellular and humoral immune responses in wild-type mice that persisted longer than those induced by the parental Wyeth strain. The superior efficacy of Wyeth IL-15 was further demonstrated by the ability of vaccinated mice to fully survive a lethal intranasal challenge of virulent vaccinia virus even 10 months after vaccination, whereas all mice vaccinated with parental Wyeth strain succumbed. By integrating IL-15 into modified vaccinia virus Ankara (MVA), a virus currently under consideration as a substitute for the Dryvax vaccine, we developed a second vaccine candidate (MVA IL-15) with greater immunogenicity and efficacy than Dryvax. Thus, Wyeth IL-15 and MVA IL-15 viruses hold promise as more-efficacious and safe alternatives to the Dryvax vaccine.
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Van Der Weyden, Martin B. "MJA/Wyeth Award 2003." Medical Journal of Australia 181, no. 2 (July 2004): 58. http://dx.doi.org/10.5694/j.1326-5377.2004.tb06169.x.

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Bodmer, George. "N.C. Wyeth: A Biography." Lion and the Unicorn 23, no. 2 (1999): 308–11. http://dx.doi.org/10.1353/uni.1999.0020.

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Shaw, Jon A. "Andrew Wyeth and N.C. Wyeth: A Psychodynamic Perspective on Father and Son." Psychiatry: Interpersonal and Biological Processes 76, no. 3 (September 2013): 187–202. http://dx.doi.org/10.1521/psyc.2013.76.3.187.

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Gostanian, Anthony. "How the FDA Can Overturn Wyeth v. Levine." American Journal of Law & Medicine 36, no. 1 (March 2010): 249–69. http://dx.doi.org/10.1177/009885881003600106.

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AbstractIn Wyeth v. Levine, the Supreme Court held that an FDA-approved drug label did not preempt state tort law. Although the Supreme Court did not defer to the FDA's position, language in the opinion, and Breyer's concurring opinion, suggest that the FDA may be able to abrogate Wyeth v. Levine using the administrative law doctrine originally announced in Chevron v. Natural Resources Defense Council. That is, the FDA may claim deference to its position in a future case involving the same legal questions. This Note explains how Wyeth impacts the Chevron doctrine and identifies how the FDA assertion that drug labels preempt state law may win in a future case.
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&NA;. "Hib-DTaP vaccine (Wyeth-Lederle)." Drugs in R & D 2, no. 3 (February 1999): 203. http://dx.doi.org/10.2165/00126839-199902030-00012.

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&NA;. "Pneumococcal Vaccine Conjugate (Wyeth-Lederle)." Drugs in R & D 2, no. 3 (February 1999): 215–19. http://dx.doi.org/10.2165/00126839-199902030-00017.

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Dissertations / Theses on the topic "Wyeth"

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Lamouliatte-Schmitt, Héléna. "Réalisme(s) et réalité(s) dans l'art d'Andrew Wyeth (1917-2009)." Bordeaux 3, 2011. https://hal.science/tel-04232903v1.

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Andrew Wyeth reste une figure contestée de l'art américain. Sa valeur marchande a atteint des sommets et la ferveur populaire à son égard ne s'est jamais démentie, alors que les historiens d'art et les critiques n'ont eu de cesse de s'interroger sur l'intérêt de son art, même depuis sa mort en 2009. Peintre figuratif depuis le début de sa carrière dans les années quarante, il fut rattaché tour à tour au Réalisme magique, puis au Régionalisme, du fait d'une propension marquée à dépeindre des scènes qualifiées d'étranges et d'un choix de sujets issus principalement d'un contexte rural, au moyen d'une technique de représentation extrêmement précise. La finalité de ce travail est de replacer l'art d'Andrew Wyeth dans la tradition de la peinture réaliste américaine et occidentale , en mettant à jour le dialogue entre l'artiste et ses prédécesseurs, notamment en ce qui concerne la représentation des paysages américains au travers du topos de la pastorale. La traditionnelle classification de son oeuvre dans l'histoire de l'art américain se trouve ainsi remise en question. Cette approche nécessite une mise au point théorique sur les concepts de réalisme et de réalité, que Wyeth interroge de manière discrète, en creux. Nous découvrons ainsi une oeuvre relativement complexe sur le plan formel (oscillant entre figuration et abstraction en particulier au niveau du travail sur la matière picturale), obsessionnelle quant au choix des sujets, et traversée par la question de la représentation de la figure de l'auteur, présence omnipotente mais demeurant esclave de symptômes que le peintre n'a eu de cesse de figurer en peinture
Andrew Wyeth is still a controversial figure in American art. Throughout his life the market value of his works increased along with his status as a fine artist acclaimed by the general public. Still, even his death in 2009 did not stop art historians and critics from questioning his legitimacy as a "serious" artist. He began his career as a figurative painter in the 1940s, and resolutely stuck to the genre. He was labeled a Magic Realist and a Regionalist, on account of his numerous depictions of "uncanny" rural scenes by means of sharp focus realism. This dissertation replaces Wyeth's artwork into the Western and American traditions of realistic painting and highlights his contant creative dialogue with his predecessors. Particular attention is paid to his representation of the American landscape and the pastoral topos in order to reassess his position in the history of American art. This reevaluation is based on the questioning of realism and reality, two notions that are consistently challenged by the artist, albeit indirectly. Wyeth's art thus appears far more complex than it may seem at first glance, poised between figuration and abstraction throught its painterly attention to textures. It resolves around an obsessive choice of themes and questions the representation of the figure of the author, ubiquitous yet exemplifying symptoms that he relentlessly depicted in his paintings
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Palencar, Christian L. "Puppet Master." Kent State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=kent1524495452335687.

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Esteves, João Pedro Monsanto. "Pfizer & Wyeth: acquiring to survive, rather than to grow." Master's thesis, 2018. http://hdl.handle.net/10362/35670.

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This case focus on the strategy that motivated Pfizer to go, by 2009, through the acquisition of Wyeth. Beyond the strategic reasons, this case will discuss the financial implications of the deal jointly analysing the impact on financial key ratios for Pfizer’s investors. As the historical Pfizer’s portfolio of acquisitions is considerably extended, its investors are left with questions about the realization of the synergies announced as well as the ability to integrate Wyeth’s business in such a tough period.
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Angelis, Ilaria De. "Is Pfizer-Wyeth merger aligned with value creation in the pharmaceutical industry?" Master's thesis, 2016. http://hdl.handle.net/10362/18608.

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Is Pfizer-Wyeth merger aligned with value creation in the pharmaceutical industry? This empirical research evaluates whether the Pfizer-Wyeth merger created value for shareholders, trying to assess if the specific case study is in line with the principal pattern of the industry. In order to achieve these goals, a detailed value creation appraisal is implemented through market reaction measurement at the announcement dates of acquisition. Afterward, a statistical regression has been performed determining which factors mainly affect enterprise’s performance. The conclusion suggests that the deal’s value creation is aligned with the pharmaceutical industry trend and that company performance is affected by financing structure, EPS and transaction size.
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Tsai, Chien-Hsiung, and 蔡建雄. "The Status of the Taiwan Pharmaceutical Industry to Research Business Strategy Planning after the Merger Pfizer, Wyeth." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/62885187361654930514.

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碩士
國立交通大學
高階主管管理碩士學程
98
A procedure is purpose of this research is to probe the change of maket share between brand drugs and generic drugs in major channels. National Health Insurance policy affects the development of pharmaceutical industry and it makes hospital's treatment policy become cost-oriented. Under this pressure, it is difficult to maintain physicians' royality. Only if new brand drug is launched to compete with generic drug, it is also difficult to maintain product price by physicians' royality. This disertation is a qualitative research, looking back to the launch day of National Health Insurance, taking brand drugcompany and generic drug company as research unit, and through data collection and interviews to probe development of marketing channels. Two biggest reasons were found and discussed: 1. How National Health Insurance policy affects treatment behaviours and medial behaviours; 2. How Price Volume Survey and price adjustment policy affect pharmaceutical companies to select target markets and channels. By looking at competitive advantages of pharmaceutical industry in Taiwan and SWOT analysis, this research is designed to probe how Pfizer finds out suitable markets and how Pfizer utilise Wyeth's brand to build product strategy. A line relationship among market price, brand and channel was found in this research. After the 6th Price Volume Survey, the competitiveness between generic drug and brand drug is getting intense. And hospital channel is the biggest market. Considering operation cost, generic drug's market share is getting bigger. But considering medical quality and drug procurement needs, cheap drug with good efficacy is getting popular. Generic drug is the majority in GP/DS channels. Brand drug company is required to allocate more manpower in National Health Insurance Drug Stores to maintain brand drug prescribe. Therefore, to set up a generic drug company or cooperate with generic company are reasonable and workable strategies for patent drug company. Moreover, befor the launch of 2nd Generation NHI, 8 pharma societies should work together to figure out the possibility of promote individual drug payment system. This will help drug price become more open and reasonable. Furthermore, this will avoid acting annual price volume survey which lowers drug payment to a non-profitable level and puts brand drug company out of market. And by setting transaction standard and standardised contract..etc. to make drug transaction become more fair and reasonable.
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Books on the topic "Wyeth"

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Museum, Delaware Art, and William A. Farnsworth Library and Art Museum., eds. Wondrous strange: The Wyeth tradition : Howard Pyle, N.C. Wyeth, Andrew Wyeth, James Wyeth. Boston: Little, Brown and Co., 1998.

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1882-1945, Wyeth N. C., Wyeth Andrew 1917-, Wyeth Jamie 1946-, Duff James H. 1943-, and Brandywine River Museum, eds. An American vision: Three generations of Wyeth art : N.C. Wyeth, Andrew Wyeth, James Wyeth. Boston: Little, Brown, 1987.

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Meryman, Richard. Andrew Wyeth. New York: H.N. Abrams, 1991.

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Zebrowski, Ewa M. Finding Wyeth. Montréal, Québec: Ewa Monika Zebrowski, 2012.

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Jennings, Kate F. N.C. Wyeth. Wigston, Leicester: Magna Books, 1992.

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Wyeth, N. C. N.C. Wyeth. New York: Crescent Books, 1992.

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Wyeth, N. C. The Wyeths: The letters of N.C. Wyeth, 1901-1945. 2nd ed. Chadds Ford, PA: Brandywine River Museum of the Brandywine Conservancy, 2008.

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Andrew Wyeth, autobiography. Boston: Bulfinch Press, 1995.

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E, Strickler Susan, Currier Museum of Art, and William A. Farnsworth Library and Art Museum., eds. Andrew Wyeth: Early watercolors. Manchester, N.H: Currier Museum of Art, 2004.

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Michaelis, David. N.C. Wyeth: A biography. New York: Knopf, 1998.

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Book chapters on the topic "Wyeth"

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Hjorth, Richard N., Geraldine M. Bonde, Elizabeth D. Piner, Kenneth M. Goldberg, Daniel M. Teller, Mark Hite, Steven K. Vernon, Mark H. Levner, and Paul P. Hung. "Influenza Vaccines and the Wyeth-Ayerst Experience with Syntex Adjuvant." In Vaccines, 43–58. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3848-6_6.

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Carpenter, Sarah, John J. McGavin, and Greg Walker. "‘Gely Wyth Tharmys of Scotland England’." In Early Performance: Courts and Audiences, 40–51. Abingdon, Oxon ; New York : Routledge, 2020. | Series: Variorum collected studies series: Routledge, 2020. http://dx.doi.org/10.4324/9780429269042-5.

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Perry, Ryan, and Lawrence Tuck. "“[W]heþyr þu redist er herist redyng, I wil be plesyd wyth þe”: Margery Kempe and the Locations for Middle English Devotional Reading and Hearing." In Spaces for Reading in Later Medieval England, 133–48. New York: Palgrave Macmillan US, 2016. http://dx.doi.org/10.1057/9781137428622_9.

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Logsdon, Gene. "Andrew Wyeth." In The Mother of All Arts, 53–71. University Press of Kentucky, 2007. http://dx.doi.org/10.5810/kentucky/9780813124438.003.0006.

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Logsdon, Gene. "N. C. Wyeth." In The Mother of All Arts, 31–38. University Press of Kentucky, 2007. http://dx.doi.org/10.5810/kentucky/9780813124438.003.0004.

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"Postcards to Andrew Wyeth." In Almanac, 52–53. Princeton: Princeton University Press, 2013. http://dx.doi.org/10.1515/9781400848034-030.

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Nyong'o, Tavia. "Conclusion." In Afro-Fabulations, 199–212. NYU Press, 2018. http://dx.doi.org/10.18574/nyu/9781479856275.003.0010.

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The conclusion expounds a theory of afro-fabulative poetics of memory through a discussion of the concept of the crypt in the psychoanalysis of Torok and Abraham, as interpreted through the performance and film work of artist Geo Wyeth. Critical and creative fabulation is a means of decrypting blackness while preserving opacity.
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Taber, Douglass. "Functional Group Transformations." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0004.

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Jeffrey C. Pelletier of Wyeth Research, Collegeville, PA has developed (Tetrahedron Lett. 2007, 48, 7745) a easy work-up Mitsunobu procedure for the conversion of a primary alcohol such as 1 to the corresponding primary amine 2. Shlomo Rozen of Tel-Aviv University has taken advantage (J. Org. Chem. 2007, 72, 6500) of his own method for oxidation of a primary amine to the nitro compound to effect net conversion of an amino ester 3 to the alkylated amino ester 5. Note that the free amine of 3 or 5 would react immediately with methyl iodide. Keith A. Woerpel of the University of California, Irvine has uncovered (J. Am. Chem. Soc. 2007, 129, 12602) a Cu catalyst that, with 7, effected direct conversion of silyl ethers such as 6 to the allyl silane 8. An Ag catalyst gave 9, which also shows arllyl silane reactivity. Biswanath Das of the Indian Institute of Chemical Technology, Hyderabad has established (Tetrahedron Lett. 2007, 48, 6681) a compact procedure for the direct conversion of an aromatic aldehyde such as 10 to the benzylic halide 11. This will be especially useful for directly generating benzylic halides that are particularly reactive. α-Sulfinylation of ketones often requires intial generation of the enolate. J. S. Yadav, also of the Indian Institute of Chemical Technology, Hyderabad, has devised (Tetrahedron Lett. 2007, 48, 5243) an oxidative protocol for installing sulfur adjacent to a ketone. In a related development, Richard S. Grainger of the University of Birmingham has established (Angew. Chem. Int. Ed. 2007, 46, 5377) a simple procedure for the conversion of thio esters such as 14 to the corresponding ketone 16. Yoshiya Fukumoto of Osaka University has shown (J. Am. Chem. Soc. 2007, 129, 13792) that a terminal alkyne 17 can be directly converted into the enamine 18 by Rh-catalyzed addition of a secondary amine. Lukas Hintermann and Carsten Bolm of RWTH Aachen have found (J. Org. Chem. 2007, 72, 5704) that inclusion of water gave the aldehyde, which could be oxidized with the residual Ru catalyst to the acid.
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Saltzman, W. Mark. "Controlled Drug Delivery Systems." In Drug Delivery. Oxford University Press, 2001. http://dx.doi.org/10.1093/oso/9780195085891.003.0015.

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In most forms of drug delivery, spatial localization and duration of drug concentration are constrained by organ physiology and metabolism. For example, drugs administered orally will distribute to tissues based on the principles of diffusion, permeation, and flow presented in Part II of this book. If the duration of therapy provided by a single administration is insufficient, the drug must be readministered. Localization of drug can be controlled by injection, but only within limited spatial constraints, and effectiveness after an injection is usually short-lived. Controlled-delivery systems offer an alternative approach to regulating both the duration and spatial localization of therapeutic agents. In controlled delivery, the active agent is combined with other (usually synthetic) components to produce a delivery system. Unlike drug modification, which results in new agents that are single molecules, or assemblies of a limited number of molecules, drug delivery systems are usually macroscopic. Like drug modification, controlled-delivery systems frequently involve combinations of active agents with inert polymeric materials. In this text, controlled-delivery systems are distinguished from “sustained-release” drug formulations. Sustained release is often achieved by mixing an active agent with excipients or binders that alter the agent’s rate of dissolution in the intestinal tract or adsorption from a local injection site. The distinction between sustained release (often achieved by drug formulation) and controlled delivery or controlled release is somewhat arbitrary. In our definition, controlled delivery systems must (1) include a component that can be engineered to regulate an essential characteristic (e.g., duration of release, rate of release, or targeting) and (2) have a duration of action longer than a day. Many polymeric materials are available for the development of drug delivery systems (see Appendix A). Non-degradable, hydrophobic polymers have been used the most extensively. Reservoir drug delivery devices, in which a liquid reservoir of drug is enclosed in a silicone elastomer tube, were first demonstrated to provide controlled release of small molecules several decades ago [1]. This discovery eventually led to clinically useful devices, including the Norplant® (Wyeth-Ayerst Laboratories) contraceptive delivery system, which provides reliable delivery of levonorgestrel for 5 years following subcutaneous implantation.
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Li, Jie Jack. "Beginning of an Era: The First Blockbuster Drug, Tagamet." In Blockbuster Drugs. Oxford University Press, 2014. http://dx.doi.org/10.1093/oso/9780199737680.003.0005.

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Tagamet emerged as the first blockbuster drug when its sales exceeded $1 billion in 1986, three years after its introduction to the market. An anti–peptic ulcer drug, Tagamet was discovered by James W. Black and his colleagues at Smith Kline & French’s (SK&F) British subsidiary in Welwyn Garden City. Before Tagamet, SK&F was a little-known U.S. drug firm in Philadelphia. After Tagamet, SK&F became one of the largest pharmaceutical companies in the world. The history of Tagamet is one of the most extraordinary in the annals of medicine. It is a saga of a drug that almost escaped detection because the research efforts that began in 1964 did not seem to produce results within the first 11 years! Smith Kline started as a humble drug store in Philadelphia in 1830. During the American Civil War, Smith Kline was founded as a small apothecary by two physicians, John K. Smith and John Gilbert on North Second Street. Not only was Philadelphia the birthplace of the United States of America, it was also the cradle of American pharmacy. Wyeth, McNeil, Rorer, and Warner-Lambert all trace their origins to small drug stores established there during the Civil War. In the 1880s, Mahlon N. Kline led the company into research and manufacturing of its own products. In 1891, it absorbed French, Richards & Co. founded by Harry B. French, creating Smith Kline & French. After its establishment, the company slowly expanded its inventory. By the 1920s, it had some 15,000 products ranging from aspirin to liniment. Their Eskay’s Albumenized Food was highly popular as a digestible food for infants and the disabled. Later, the company did very well with Eskay’s Tablets for Seasickness. Its specialty, Eskay’s Neurophosphates, a nerve tonic, soothed millions of people at home and abroad. In 1929, Smith Kline & French Laboratories was created to devote itself solely to research and development (R&D). During the Great Depression year of 1936, the company stepped up its efforts in R&D (in a recent contrast, many pharmaceutical companies stepped down their R&D investments during the last recession of 2008).
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Reports on the topic "Wyeth"

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Walk-through survey report: control technology for fermentation processes at Wyeth Laboratories, Inc., West Chester, Pennsylvania. U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, October 1985. http://dx.doi.org/10.26616/nioshectb11618a.

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