Relevant bibliographies by topics / X-chromosome inactivation

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  2. Dissertations / Theses
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Academic literature on the topic 'X-chromosome inactivation'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "X-chromosome inactivation"

1

Sado, Takashi, and Takehisa Sakaguchi. "Species-specific differences in X chromosome inactivation in mammals." REPRODUCTION 146, no. 4 (2013): R131—R139. http://dx.doi.org/10.1530/rep-13-0173.

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In female mammals, the dosage difference in X-linked genes between XX females and XY males is compensated for by inactivating one of the two X chromosomes during early development. Since the discovery of the X inactive-specific transcript (XIST) gene in humans and its subsequent isolation of the mouse homolog, Xist, in the early 1990s, the molecular basis of X chromosome inactivation (X-inactivation) has been more fully elucidated using genetically manipulated mouse embryos and embryonic stem cells. Studies on X-inactivation in other mammals, although limited when compared with those in the mi
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Cattanach, Bruce M., and Colin V. Beechey. "Autosomal and X-chromosome imprinting." Development 108, Supplement (1990): 63–72. http://dx.doi.org/10.1242/dev.108.supplement.63.

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Mouse genetic studies using Robertsonian and reciprocal translations have shown that certain autosomal regions of loci are subject to a parental germ line imprint, which renders maternal and paternal copies functionally inequivalent in the embryo or later stages of development. Duplication of maternal or paternal copies with corresponding paternal/maternal deficiencies in chromosomally balanced zygotes causes various effects. These range from early embryonic lethalities through to mid-fetal and neonatal lethalities, and in some instances viable young with phenotypic effects are obtained. Eight
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Rastan, Sohaila, and Elizabeth J. Robertson. "X-chromosome deletions in embryo-derived (EK) cell lines associated with lack of X-chromosome inactivation." Development 90, no. 1 (1985): 379–88. http://dx.doi.org/10.1242/dev.90.1.379.

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The predictions of a model for the initiation of X-chromosome inactivation based on a single inactivation centre were tested in a cytogenetic study using six different embryo-derived (EK) stem cell lines, each with a different-sized deletion of the distal part of one of the X-chromosomes. Metaphase chromosomes were prepared by the Kanda method from each cell line in the undifferentiated state and after induction of differentiation, and cytogenetic evidence sought for a dark-staining inactive X-chromosome. The results confirm the predictions of the model in that when the inactivation centre is
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Malcore, Rebecca M., and Sundeep Kalantry. "A Comparative Analysis of Mouse Imprinted and Random X-Chromosome Inactivation." Epigenomes 8, no. 1 (2024): 8. http://dx.doi.org/10.3390/epigenomes8010008.

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The mammalian sexes are distinguished by the X and Y chromosomes. Whereas males harbor one X and one Y chromosome, females harbor two X chromosomes. To equalize X-linked gene expression between the sexes, therian mammals have evolved X-chromosome inactivation as a dosage compensation mechanism. During X-inactivation, most genes on one of the two X chromosomes in females are transcriptionally silenced, thus equalizing X-linked gene expression between the sexes. Two forms of X-inactivation characterize eutherian mammals, imprinted and random. Imprinted X-inactivation is defined by the exclusive
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Shevchenko, A. I. "The phenomenon of X chromosome inactivation and human diseases." Genes & Cells 11, no. 2 (2016): 61–69. http://dx.doi.org/10.23868/gc120579.

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In early development, one of the two X chromosomes is randomly inactivated in each somatic cell of female embryos. As a result, women are mosaics that means about a half of their cells bear the active X chromosome inherited from the father, while the genes of the maternally inherited X chromosome are expressed in the other half. Disturbance in the inactivation process during embryogenesis leads to fetal death. Reactivation of the inactive X chromosome in female cells can cause a number of diseases, including cancer and autoimmune disorders. Changes in randomness of X-chromosome inactivation an
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Migeon, Barbara R. "X chromosome inactivation." Genome 31, no. 1 (1989): 464. http://dx.doi.org/10.1139/g89-083.

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Lyon, Mary F. "X-chromosome inactivation." Current Biology 9, no. 7 (1999): R235—R237. http://dx.doi.org/10.1016/s0960-9822(99)80151-1.

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Shevchenko, Alexander I., Elena V. Dementyeva, Irina S. Zakharova, and Suren M. Zakian. "Diverse developmental strategies of X chromosome dosage compensation in eutherian mammals." International Journal of Developmental Biology 63, no. 3-4-5 (2019): 223–33. http://dx.doi.org/10.1387/ijdb.180376as.

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In eutherian mammals, dosage compensation arose to balance X-linked gene expression between sexes and relatively to autosomal gene expression in the evolution of sex chromosomes. Dosage compensation occurs in early mammalian development and comprises X chromosome upregulation and inactivation that are tightly coordinated epigenetic processes. Despite a uniform principle of dosage compensation, mechanisms of X chromosome inactivation and upregulation demonstrate a significant variability depending on sex, developmental stage, cell type, individual, and mammalian species. The review focuses on r
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Shevchenko, A. I., I. S. Zakharova, and S. M. Zakian. "The Evolutionary Pathway of X Chromosome Inactivation in Mammals." Acta Naturae 5, no. 2 (2013): 40–53. http://dx.doi.org/10.32607/20758251-2013-5-2-40-53.

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X chromosome inactivation is a complex process that occurs in marsupial and eutherian mammals. The process is thought to have arisen during the differentiation of mammalian sex chromosomes to achieve an equal dosage of X chromosome genes in males and females. The differences in the X chromosome inactivation processes in marsupial and eutherian mammals are considered, and the hypotheses on its origin and evolution are discussed in this review.
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Lyon, M. F. "X Chromosome Inactivation and Imprinting." Acta geneticae medicae et gemellologiae: twin research 45, no. 1-2 (1996): 85. http://dx.doi.org/10.1017/s0001566000001148.

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In contrast to the random inactivation of either maternal or paternal X-chromosome in the somatic cells of eutherian mammals, in marsupials the paternal X-chromosome is preferentially inactivated in all cells. Similar exclusively paternal X-inactivation occurs in two extraembryonic cell lineages of mice and rats. Thus, genetic imprinting is an important feature of X-inactivation. In embryonic development the initiation of X-inactivation is thought to occur through the X-inactivation centre, located on the X-Chromosome, and thus imprinting probably acts through this centre. A candidate gene for
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Dissertations / Theses on the topic "X-chromosome inactivation"

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Norris, Dominic Paul. "X chromosome inactivation in the mouse." Thesis, Open University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282142.

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Benjamin, Don. "Molecular studies of human X chromosome inactivation." Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318784.

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Paterno, Gary David. "X chromosome inactivation in mouse embryonal carcinoma cells." Thesis, University of Ottawa (Canada), 1985. http://hdl.handle.net/10393/4629.

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Metello, de Napoles Mariana. "Epigenetic modifications during X-chromosome inactivation and reactivation." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422058.

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Ager, Miranda. "Mechanisms of X chromosome inactivation : a transgenic approach." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342240.

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林德深 and Tak-sum Lam. "A biochemical study of mammalian x chromosome inactivation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1987. http://hub.hku.hk/bib/B31981306.

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Dossin, François. "Mechanistic dissection of SPEN functionduring X chromosome inactivation." Thesis, Université Paris sciences et lettres, 2021. http://www.theses.fr/2021UPSLS042.

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Chez les mammifères placentaires femelles, la transcription d’un des deux chromosomes X est inactivée (ICX) au cours du développement embryonnaire. Cette inactivation est permise par Xist, un ARN non-codant qui recouvre le chromosome X à partir duquel il est exprimé, induisant ensuite l’extinction transcriptionnelle de tout ce chromosome. Les mécanismes moléculaires par lesquels Xist permet une telle répression des gènes liés à l’X demeurent globalement incompris. En 2015, la protéine SPEN a été identifiée comme interagissant directement avec l’ARN de Xist, mais sa fonction précise ainsi que s
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Lam, Tak-sum. "A biochemical study of mammalian x chromosome inactivation." [Hong Kong : University of Hong Kong], 1987. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12827186.

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Forrester, Lesley Margaret. "Murine haematopoiesis : studies using X chromosome-inactivation mosaics." Thesis, University of Edinburgh, 1987. http://hdl.handle.net/1842/28042.

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Blood erythrocytes and leukocytes were serially sampled over many months from female mice that were heterozygous at the X-chromosomal locusencoding the glycolytic enzyme phosphoglycerate kinase (PGK-1). PGK-1A andPGK-1B alloenzymes were identified and quantified electrophoretically. There was little variation in PGK-1 phenotype between serial samples from individual mice. This small amount of variation was discussed in terms of the number of clones participating in haematopoiesis and the contribution of technical factors. Similar studies were performed using radiation chimaeras, repopulated wi
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Sprong, Amy Nicole. "X Chromosome Aneuploidy: A Look at the Effects of X Inactivation." Miami University Honors Theses / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=muhonors1209079846.

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Books on the topic "X-chromosome inactivation"

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Sado, Takashi, ed. X-Chromosome Inactivation. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8766-5.

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Spotswood, Hugh Timothy. Histone modification and the epigenetics of X chromosome inactivation. University of Birminghm, 2002.

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Michalickova, Katerina. X-chromosome inactivation in females with deletions at Xq27-q28. National Library of Canada, 1996.

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Sado, Takashi. X-Chromosome Inactivation: Methods and Protocols. Springer New York, 2018.

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Sado, Takashi. X-Chromosome Inactivation: Methods and Protocols. Springer New York, 2019.

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Brown, Carolyn Janet *. Studies of human X chromosome inactivation. 1991.

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Migeon, Barbara. Females Are Mosaics: X Inactivation and Sex Differences in Disease. Oxford University Press, 2007.

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Migeon, Barbara. Females Are Mosaics: X Inactivation and Sex Differences in Disease. Oxford University Press, USA, 2007.

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Migeon, Barbara. Females Are Mosaics: X Inactivation and Sex Differences in Disease. Oxford University Press, 2013.

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Erwin, Jennifer Ann. Regulation of imprinted X-chromosome inactivation in stem cells and the early embryo. 2010.

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Book chapters on the topic "X-chromosome inactivation"

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Gartler, S. M. "X Chromosome Inactivation." In Human Genetics. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71635-5_22.

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Lee, Jeannie T. "X-Chromosome Inactivation." In Development. Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-642-59828-9_25.

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Robinson, Wendy P., Allison M. Cotton, Maria S. Peñaherrera, Samantha B. Peeters, and Carolyn J. Brown. "X-Chromosome Inactivation." In Epigenetics and Complex Traits. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-8078-5_3.

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Brahmachari, Vani, and Shruti Jain. "X Chromosome Inactivation." In Encyclopedia of Systems Biology. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_859.

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Adams, Roger L. P., and Roy H. Burdon. "X-Chromosome Inactivation." In Molecular Biology of DNA Methylation. Springer New York, 1985. http://dx.doi.org/10.1007/978-1-4612-5130-9_9.

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Lyon, Mary F. "X-Chromosome Inactivation." In Encyclopedia of Genetics. Routledge, 2014. http://dx.doi.org/10.4324/9781315073972-116.

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Jaenisch, Rudolf, Caroline Beard, Jeannie Lee, York Marahrens, and Barbara Panning. "Mammalian X Chromosome Inactivation." In Novartis Foundation Symposia. John Wiley & Sons, Ltd., 2007. http://dx.doi.org/10.1002/9780470515501.ch12.

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Lyon, Mary F. "Imprinting and X-Chromosome Inactivation." In Results and Problems in Cell Differentiation. Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-540-69111-2_4.

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Schorderet, Daniel F., and Stanley M. Gartler. "Steroid Sulphatase Inactivation Patterns and X-chromosome Inactivation." In Trends in Chromosome Research. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-662-10621-1_8.

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Ma, Wenxiu, Giancarlo Bonora, Joel B. Berletch, Xinxian Deng, William S. Noble, and Christine M. Disteche. "X-Chromosome Inactivation and Escape from X Inactivation in Mouse." In Methods in Molecular Biology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8766-5_15.

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Conference papers on the topic "X-chromosome inactivation"

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"X-chromosome Inactivation in American Mink iPSCs." In Bioinformatics of Genome Regulation and Structure/ Systems Biology. institute of cytology and genetics siberian branch of the russian academy of science, Novosibirsk State University, 2020. http://dx.doi.org/10.18699/bgrs/sb-2020-310.

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Song, Yilin, Bryan M. McCauley, Melissa C. Larson, et al. "Abstract 2452: Evidence of decreased X chromosome inactivation in primary ovarian tumors." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-2452.

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Ibeawuchi, Helen, Nicole Werner, and Les Keniston. "Role of X chromosome Inactivation Escapees andATMGene in Breast Neoplasia Severity and Survival." In ASPET 2024 Annual Meeting Abstract. American Society for Pharmacology and Experimental Therapeutics, 2024. http://dx.doi.org/10.1124/jpet.405.944050.

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Castellini-Pérez, Olivia, Elena Povedano-Espejo, Guillermo Barturen, et al. "O5 Exploring the impact of genome-wide DNA methylation alterations on chromosome X inactivation and female lupus." In 14th European Lupus Meeting, Bruges, Belgium, March 19–22, 2024. Lupus Foundation of America, 2024. http://dx.doi.org/10.1136/lupus-2024-el.15.

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Winham, Stacey J., Nicholas B. Larson, Sebastian M. Armasu, et al. "Abstract 2420: Integrative analyses of gene expression, DNA methylation, genotype and copy number alterations characterize X-chromosome inactivation in ovarian cancer." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2420.

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Manié, E., T. Popova, A. Vincent-Salomon, et al. "P3-06-03: Hypodiploidy, 1pter Loss and Inactive X Chromosome Retention Are Associated with BRCA1 Somatic or Germline Inactivation in Basal-Like Breast Carcinomas: Proposal for a New BRCAness Genomic Signature." In Abstracts: Thirty-Fourth Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 6‐10, 2011; San Antonio, TX. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/0008-5472.sabcs11-p3-06-03.

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Reports on the topic "X-chromosome inactivation"

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Panning, Barbara. X Chromosome Inactivation and Breast Cancer: Epigenetic Alteration in Tumor Initiation and Progression. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada474949.

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