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Relevant bibliographies by topics / X/Motif (Computer program)

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Academic literature on the topic 'X/Motif (Computer program)'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 February 2022

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Journal articles on the topic "X/Motif (Computer program)"

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Trush, V. A., N. S. Kariaka, I. S. Konovalova, S. V. Shishkina, and V. M. Amirkhanov. "Synthesis, crystal structure, Hirschfeld surface analysis and biological activity prediction of N-(dimethoxyphosphoryl)-1-methylpyridinium-4-carboximidate." Voprosy Khimii i Khimicheskoi Tekhnologii, no. 3 (May 2021): 137–44. http://dx.doi.org/10.32434/0321-4095-2021-136-3-137-144.

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N-(dimethoxyphosphoryl)-1-methylpyridinium-4-carboximidate, a new carbacylamidophosphate-type compound, was synthesized and characterized by means of IR, 1H and 31P NMR and UV-Vis spectroscopies and X-ray analysis. The molecule of the synthesized compound has triclinic (P-1) symmetry, displays monomeric motif in crystal and crystalizes as solvate containing methanol molecule, which is connected to carbacylamidophosphate molecule through O(2)H(5A)–O(5) hydrogen bond. Through – stacking interactions, the molecules of the synthesized compound are linked in the chain along the a crystallographic axis. Several other intermolecular bonds connect these chains along b and c crystallographic axes. The intermolecular interactions with HH and OH contacts prevail in the crystalline structure of N-(dimethoxyphosphoryl)-1-methylpyridinium-4-carboximidate, the contribution of planar stacking CC contacts being equal to 4.1%. The synthesized compound was found to be well soluble in water. By using computer program PASS, we established that the synthesized substance is likely can exhibit 18 types of biological activity in experiment.

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Kingsford, Carl, Elena Zaslavsky, and Mona Singh. "A cost-aggregating integer linear program for motif finding." Journal of Discrete Algorithms 9, no. 4 (December 2011): 326–34. http://dx.doi.org/10.1016/j.jda.2011.04.001.

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Negi, Surendra S., and Werner Braun. "Automated Detection of Conformational Epitopes Using Phage Display Peptide Sequences." Bioinformatics and Biology Insights 3 (January 2009): BBI.S2745. http://dx.doi.org/10.4137/bbi.s2745.

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Background Precise determination of conformational epitopes of neutralizing antibodies represents a key step in the rational design of novel vaccines. A powerful experimental method to gain insights on the physical chemical nature of conformational epitopes is the selection of linear peptides that bind with high affinities to a monoclonal antibody of interest by phage display technology. However, the structural characterization of conformational epitopes from these mimotopes is not straightforward, and in the past the interpretation of peptide sequences from phage display experiments focused on linear sequence analysis to find a consensus sequence or common sequence motifs. Results We present a fully automated search method, EpiSearch that predicts the possible location of conformational epitopes on the surface of an antigen. The algorithm uses peptide sequences from phage display experiments as input, and ranks all surface exposed patches according to the frequency distribution of similar residues in the peptides and in the patch. We have tested the performance of the EpiSearch algorithm for six experimental data sets of phage display experiments, the human epidermal growth factor receptor-2 (HER-2/neu), the antibody mAb Bo2C11 targeting the C2 domain of FVIII, antibodies mAb 17b and mAb b12 of the HIV envelope protein gp120, mAb 13b5 targeting HIV-1 capsid protein and 80R of the SARS coronavirus spike protein. In all these examples the conformational epitopes as determined by the X-ray crystal structures of the antibody-antigen complexes, were found within the highest scoring patches of EpiSearch, covering in most cases more than 50% residues of experimental observed conformational epitopes. Input options of the program include mapping of a single peptide or a set of peptides on the antigen structure, and the results of the calculation can be visualized on our interactive web server. Availability Users can access the EpiSearch from our web server http://curie.utmb.edu/episearch.html Contact webraun@utmb.edu

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LAMBKIN, C. L. "Computer Program Review." Australian Journal of Entomology 34, no. 4 (November 1995): 280. http://dx.doi.org/10.1111/j.1440-6055.1995.tb01340.x.

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Wood, Reg K. "Computer Process Control Program." Journal of Engineering Education 84, no. 1 (January 1995): 51–57. http://dx.doi.org/10.1002/j.2168-9830.1995.tb00146.x.

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Feroz, Khan, Sharma Richa, Shukla Rakesh Kumar, Meena Abha, Shasany Ajit Kumar, and Sharma Ashok. "Genomic Identification of SinR Transcription Factor Binding Sites in Nitrogen Fixing Bacterium Bradyrhizobium japonicum." Open Bioinformatics Journal 3, no. 1 (May 5, 2009): 8–17. http://dx.doi.org/10.2174/1875036200903010008.

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SinR is a transcription factor which controls expression of stress tolerance sin genes related to alternate development processes under stress condition. Identification of genome wide SinR-box motif and their regulated genes has not been worked out yet in Bradyrhizobium japonicum. For this, a weight matrix of 9 bp was developed from the known promoter sequences of Bacillus subtilis, which was then used for genome wide identification of co-regulated genes. The methodology first involves phylogenetic footprinting of SinR regulated genes and then construction of scoring matrix through ‘Consensus’ and confirmation through MEME & D-Matrix tools. Genomic prediction was done through ‘Patser’ program and confirmation through ‘PossumSearch’ program in Linux system. Results showed that all the 371 predicted genes belongs to 9 different functional classes, in which 221 found in operons with more than 80% Sin-box motif similarity. Similar approach can be used in other bacteria to explore hidden genomic regulatory network.

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ROSE, M. B., P. A. GEORGHIADES, and W. B. DOWSLAND. "A Computer Program for Urology." British Journal of Urology 57, no. 3 (June 1985): 257–60. http://dx.doi.org/10.1111/j.1464-410x.1985.tb06338.x.

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Findlay, A. "Review: The Shell Hacker's Guide to X and MOTIF." Computer Bulletin 37, no. 6 (December 1, 1995): 20. http://dx.doi.org/10.1093/combul/37.6.20-a.

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Glynn, John. "Exegetical and Bible Study Computer Program." Conversations in Religion & Theology 5, no. 1 (May 2007): 116–28. http://dx.doi.org/10.1111/j.1479-2214.2007.00109.x.

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Ngo, Vu, Mengchi Wang, and Wei Wang. "Finding de novo methylated DNA motifs." Bioinformatics 35, no. 18 (February 6, 2019): 3287–93. http://dx.doi.org/10.1093/bioinformatics/btz079.

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Abstract Motivation Increasing evidence has shown that nucleotide modifications such as methylation and hydroxymethylation on cytosine would greatly impact the binding of transcription factors (TFs). However, there is a lack of motif finding algorithms with the function to search for motifs with modified bases. In this study, we expand on our previous motif finding pipeline Epigram to provide systematic de novo motif discovery and performance evaluation on methylated DNA motifs. Results mEpigram outperforms both MEME and DREME on finding modified motifs in simulated data that mimics various motif enrichment scenarios. Furthermore we were able to identify methylated motifs in Arabidopsis DNA affinity purification sequencing (DAP-seq) data that were previously demonstrated to contain such motifs. When applied to TF ChIP-seq and DNA methylome data in H1 and GM12878, our method successfully identified novel methylated motifs that can be recognized by the TFs or their co-factors. We also observed spacing constraint between the canonical motif of the TF and the newly discovered methylated motifs, which suggests operative recognition of these cis-elements by collaborative proteins. Availability and implementation The mEpigram program is available at http://wanglab.ucsd.edu/star/mEpigram. Supplementary information Supplementary data are available at Bioinformatics online.

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Dissertations / Theses on the topic "X/Motif (Computer program)"

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Cuddihy, Paul. "Compiling GEN-X knowledge bases into "C" /." Online version of thesis, 1991. http://hdl.handle.net/1850/10792.

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Asplund, Fredrik. "Parsing of X.509 certificates in a WAP environment." Thesis, Linköping University, Department of Electrical Engineering, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1455.

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This master thesis consists of three parts. The first part contains a summary of what is needed to understand a X.509 parser that I have created, a discussion concerning the technical problems I encountered during the programming of this parser and a discussion concerning the final version of the parser. The second part concerns a comparison I made between the X.509 parser I created and a X.509 parser created"automatically"by a compiler. I tested static memory, allocation of memory during runtime and utilization of the CPU for both my parser (MP) and the parser that had a basic structure constructed by a compiler (OAP). I discuss changes in the parsers involved to make the comparison fair to OAP, the results from the tests and when circumstances such as time and non-standard content in the project make one way of constructing a X.509 parser better than the other way. The last part concerns a WTLS parser (a simpler kind of X.509 parser), which I created.

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Khan, Abdul Kareem. "Electrostaticanalisys the Ras active site." Doctoral thesis, Universitat Pompeu Fabra, 2009. http://hdl.handle.net/10803/7161.

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La preorganització electrostàtica del centre actiu s'ha postulat com el mecanisme genèric de l'acció dels enzims. Així, alguns residus "estratègics" es disposarien per catalitzar reaccions interaccionant en una forma més forta amb l'estat de transició, baixant d'aquesta manera el valor de l'energia dactivació g cat. S'ha proposat que aquesta preorientació electrostática s'hauria de poder mostrar analitzant l'estabilitat electrostàtica de residus individuals en el centre actiu.
Ras es una proteïna essencial de senyalització i actúa com un interruptor cel.lular. Les característiques estructurals de Ras en el seu estat actiu (ON) són diferents de les que té a l'estat inactiu (OFF). En aquesta tesi es duu a terme una anàlisi exhaustiva de l'estabilitat dels residus del centre actiu deRas en l'estat actiu i inactiu.
The electrostatic preorganization of the active site has been put forward as the general framework of action of enzymes. Thus, enzymes would position "strategic" residues in such a way to be prepared to catalyze reactions by
interacting in a stronger way with the transition state, in this way decreasing the activation energy g cat for the catalytic process. It has been proposed that
such electrostatic preorientation should be shown by analyzing the electrostatic stability of individual residues in the active site.
Ras protein is an essential signaling molecule and functions as a switch in the
cell. The structural features of the Ras protein in its active state (ON state) are different than those in its inactive state (OFF state). In this thesis, an exhaustive analysis of the stability of residues in the active and inactive Ras active site is performed.

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Ni, Lideng. "A new approach to slant stack processing: An X-window (OSF/motif) project." Thesis, 1992. http://hdl.handle.net/1911/13637.

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A new definition for slant stack and inversion has been formulated. The different p ranges with different frequencies in the forward slant stack provide accurate reconstruction of the original data. The computing time is faster than the conventional method for the same p traces made in the forward transform. Its applications presenting in this thesis have been satisfactory in seismic data processing.

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Books on the topic "X/Motif (Computer program)"

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An X/Motif programmer's primer. New York: Prentice Hall, 1994.

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Johnson, Eric F. Motif: Power programming. Portland, Oregon: MIS Press, 1991.

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Rost, Randi J. X and Motif quick reference guide. (Bedford,Mass.): Digital, 1990.

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Foster-Johnson, Eric. Power programming-- Motif. 2nd ed. New York, NY: MIS Press, 1993.

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Foster-Johnson, Eric, and Eric F. Johnson. Power programming... Motif. Portland, Or: MIS Press, 1991.

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Barkakati, Nabajyoti. UNIX desktop guide to X/Motif. Edited by Kochan Stephen and Wood Patrick H. Carmel, Ind., USA: Hayden Books, 1991.

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Mark, Riches, ed. Advanced motif programming techniques. New York: Prentice Hall, 1994.

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Mastering OSF/motif widgets. Reading, Mass: Addison-Wesley, 1992.

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McMinds, Donald L. Mastering OSF/Motif widgets. 2nd ed. Reading, Mass: Addison-Wesley, 1993.

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Young, Douglas A. Motif debugging and performance tuning. Englewood Cliffs, N.J: PTR Prentice Hall, 1995.

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Book chapters on the topic "X/Motif (Computer program)"

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Yager, D. B., and J. E. Quick. "Superxap-- A Personal-Computer-Based Program for Energy-Dispersive X-Ray Spectra Analysis." In Advances in X-Ray Analysis, 17–25. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2972-9_3.

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Iwaniak, Marek, and Włodzimierz Khadzhynov. "Colored Petri Net Model of X/Open Distributed Transaction Processing Environment with Single Application Program." In Communications in Computer and Information Science, 20–29. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-06932-6_3.

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Hovestreydt, E., E. Parthé, and U. Benedict. "Endix — a computer program to simulate energy dispersive X-ray and synchrotron powder diffraction diagram." In Chemical Crystallography with Pulsed Neutrons and Synchroton X-rays, 571–72. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-4027-7_30.

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Glasgow, Janice, and Evan Steeg. "Motif Discovery in Protein Structure Databases." In Pattern Discovery in Biomolecular Data. Oxford University Press, 1999. http://dx.doi.org/10.1093/oso/9780195119404.003.0011.

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The field of knowledge discovery is concerned with the theory and processes involved in the representation and extraction of patterns or motifs from large databases. Discovered patterns can be used to group data into meaningful classes, to summarize data, or to reveal deviant entries. Motifs stored in a database can be brought to bear on difficult instances of structure prediction or determination from X-ray crystallography or nuclear magnetic resonance (NMR) experiments. Automated discovery techniques are central to understanding and analyzing the rapidly expanding repositories of protein sequence and structure data. This chapter deals with the discovery of protein structure motifs. A motif is an abstraction over a set of recurring patterns observed in a dataset; it captures the essential features shared by a set of similar or related objects. In many domains, such as computer vision and speech recognition, there exist special regularities that permit such motif abstraction. In the protein science domain, the regularities derive from evolutionary and biophysical constraints on amino acid sequences and structures. The identification of a known pattern in a new protein sequence or structure permits the immediate retrieval and application of knowledge obtained from the analysis of other proteins. The discovery and manipulation of motifs—in DNA, RNA, and protein sequences and structures—is thus an important component of computational molecular biology and genome informatics. In particular, identifying protein structure classifications at varying levels of abstraction allows us to organize and increase our understanding of the rapidly growing protein structure datasets. Discovered motifs are also useful for improving the efficiency and effectiveness of X-ray crystallographic studies of proteins, for drug design, for understanding protein evolution, and ultimately for predicting the structure of proteins from sequence data. Motifs may be designed by hand, based on expert knowledge. For example, the Chou-Fasman protein secondary structure prediction program (Chou and Fasman, 1978), which dominated the field for many years, depended on the recognition of predefined, user-encoded sequence motifs for α-helices and β-sheets. Several hundred sequence motifs have been cataloged in PROSITE (Bairoch, 1992); the identification of one of these motifs in a novel protein often allows for immediate function interpretation.

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"Computer Program for Thermodynamic Properties." In Handbook of Thermodynamic Diagrams, 396. Elsevier, 1996. http://dx.doi.org/10.1016/b978-0-08-050786-6.50017-x.

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"Computer Program for Beams “BEAMSF”." In Finite Element Programs in Structural Engineering and Continuum Mechanics, 332–39. Elsevier, 1996. http://dx.doi.org/10.1016/b978-1-898563-28-0.50027-x.

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Svoboda, I. F. "A COMPUTER PROGRAM FOR FARM WASTE MANAGEMENT." In Water Pollution Research and Control Brighton, 1865–68. Elsevier, 1988. http://dx.doi.org/10.1016/b978-1-4832-8439-2.50208-x.

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"Computer Program for Rigid/Pin-Jointed Plane Frames “FRAMERP”." In Finite Element Programs in Structural Engineering and Continuum Mechanics, 361–78. Elsevier, 1996. http://dx.doi.org/10.1016/b978-1-898563-28-0.50030-x.

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Coomes, P. A. "PLEM: A COMPUTER PROGRAM FOR PASSIVE LEARNING STOCHASTIC CONTROL EXPERIMENTS." In Dynamic Modelling and Control of National Economies 1986, 385–89. Elsevier, 1987. http://dx.doi.org/10.1016/b978-0-08-034795-0.50070-x.

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"Computer Program for the Vibration of Doubly-Curved Shells “VIBSHELF”." In Finite Element Programs in Structural Engineering and Continuum Mechanics, 545–61. Elsevier, 1996. http://dx.doi.org/10.1016/b978-1-898563-28-0.50044-x.

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Conference papers on the topic "X/Motif (Computer program)"

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Ho, Chengta, A. G. Erdman, and Donald R. Riley. "MinnSketch©: A Graphic Kinematic and Dynamic Analysis Tool for Planar Mechanism Design." In ASME 1994 Design Technical Conferences collocated with the ASME 1994 International Computers in Engineering Conference and Exhibition and the ASME 1994 8th Annual Database Symposium. American Society of Mechanical Engineers, 1994. http://dx.doi.org/10.1115/detc1994-0282.

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Abstract MinnSketch© is a new conceptual design package for the generation of planar mechanisms. This program is implemented in C and runs in an X/Motif graphic environment. MinnSketch allows users to intuitively construct a mechanism from scratch and to rapidly develop the conceptual model to a workable solution. The purpose of developing this program was to create an intuitive design tool, so the user interface was designed to closely model the real-world environment. By directly manipulating the graphic conceptual model intuitively with the aid of the feedback from the simulation and analysis results, users can thoroughly understand their designs and thus can increase their productivity.

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Mertens, G., R. C. R. Rob Reynolds III, and R. A. Rieko Adriaens. "NEWMOD-2 - A Computer Program for Qualitative and Quantitative 1-D X-ray Diffraction Pattern Modeling." In Fifth EAGE Shale Workshop. Netherlands: EAGE Publications BV, 2016. http://dx.doi.org/10.3997/2214-4609.201600406.

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Martin, David E. "PCLINES, A Parametric Lines Development Program for the Home Computer." In SNAME 18th Chesapeake Sailing Yacht Symposium. SNAME, 2007. http://dx.doi.org/10.5957/csys-2007-011.

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An Excel© spreadsheet lines development program has been written for a home computer and is available to conference attendees. The program utilizes B-Spline parametric formulations for planar curve definition of the traditional hull lines: body, waterlines and buttocks. The user establishes the basic hull outline, in BSpline curves, by inputting bow and stern overhangs, freeboard at selected points, the draft of the canoe body at selected points, the beam on deck at selected points, and the maximum beam at the waterline. By judicious selections the user will see the resulting hull outline in profile and plan views, and can easily adjust these inputs to gain the desired hull outline. The user works with actual points on the hull rather than B-Spline vertices. The hull lines are then developed by the Excel program which establishes the hull form defined by the above outlines and satisfying inputs of the conventional hull form parameters: Center of Buoyancy, (Lcb) Center of Floatation, (Lcf) Prismatic Coefficient, (Cp), Maximum Section Coefficient, (Cm) and the Water-plane Coefficient, (Cwp). The lines development is accomplished in two steps. First, the user employs the Excel Solver to establish a waterline, and Sectional Area curve that satisfy the above parameters. The program accomplishes this by varying the draft at stations two and eight, which adjusts the shape of the center-plane curve without changing the draft, Tc. The solver ensures a “fair” waterline by minimizing the “bending” criterion of the waterline: that is, by minimizing the sum of the squares of d2y/du2 and d2x/du2. Here, y and x are defined by B-Spline formulations in the parameter “u”. The vertices of the B-Spline functions are varied by the Excel Solver to find the minimum bending criterion. Second, with the Section Area and waterline beam established for each station, the program establishes the shape of each station body curve which satisfies the section area, draft, freeboard and beams on deck and waterline. Fairness is again established by minimizing the “bending” criterion. Since there are no section areas for stations 10 and the transom, a scheme for constructing a transomgeometrically similar to station 9.5 is provided. Station 10 is established by fairing to the transom. The program can establish a round bottom hull in about a minute and a half after the input parameters are entered. It is essential however that the hull form parameters be selected judiciously. Clearly Lcb and Lcf must be compatible, and the hull outline must be reasonable in order to gain a fair hull. In this regard the user is provided with automatic input of six different hull shapes that provide good starting points for a design effort. Thus, in a matter of minutes the user can examine an alternate hull shape while keeping selected hull form parameters constant.

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Huang, Yuan Mao, and Chun-Ting Huang. "The Disassembly Matrix for Computer-Aided Disassembly." In ASME 2000 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/detc2000/dac-14530.

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Abstract This study proposes an effective and feasible method that improves the existing methods for disassembly. The elements of three dimensional interference matrices in the directions of x, y and z axes are considered as the low bit, middle bit and high bit, respectively, for the elements of the proposed disassembly matrix in the binary system. By using the Boolean operation and the deep-first-search method, the algorithm is developed and a software program is generated to create all of the possible disassembly sequences and directions of components in the tree diagram. With the grades for change of the disassembly directions, the optimum disassembly sequences can be determined. This disassembly matrix not only can help disassemble the disposed devices but also can evaluate the potential products during design.

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Huo, Y., X. Ai, and B. Q. Li. "Computation and Visualizaion of 3-D Marangoni and Magnetically-Driven Flows in Droplets." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-42822.

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This paper presents a computational and visualization tool kit for the numerical modeling of 3-D Marangoni and/or magnetically-driven turbulent flows in droplets under normal and/or microgravity conditions. The computational part involves the finite element solution of steady-state and transient 3-D Marangoni flows in electrically levitated droplets and the higher order finite difference method for the direction numerical simulation of tubulences in electromagnetically levitated droplets. Both the electrically and magnetically droplets have been used for study of fundamentals governing solidification processing in normal and mcrio gravity. The visualization part is developed based on the UNIX/X-motif platform and on the advanced algorithms for multi-dimensional computer graphics. The visualization tool kit employs the algorithms for data retrieving, partitoning, sorting and searching algorithms, and 3-D/2-D object clipping. An efficient algorithm used for plane and body cutting and particle tracing is presented. The mathematical formulation used in developing the above computational tool kit, including computational and differential geometry, is also discussed. Examples are given to illustrate the effectiveness and efficiency of the tool kit as applied to the numerical simulation and computer visualization of complex steady state and transient three-dimensional Marangoni and turbulent magnetically driven flows in free droplets.

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Chen, Chih-Wei, Hong-Sen Kou, Hsueh-Erh Liu, Cheng-Keng Chuang, and Li-Jen Wang. "Computer Assisted Simulation Model in Cryosurgery for Prostate Tumor." In ASME 2009 Heat Transfer Summer Conference collocated with the InterPACK09 and 3rd Energy Sustainability Conferences. ASMEDC, 2009. http://dx.doi.org/10.1115/ht2009-88575.

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Cryosurgery is also called as cryoablation or cryoleision. The third generation of cryo-machine use argon gas for cooling and helium for rewarming to destroy cancer cells. The probes may be put into the tumor during surgery or through the skin (percutaneously). After cryosurgery, the frozen tissue thaws and is either naturally absorbed by the body (for internal tumors), or it dissolves and forms a scab (for external tumors). The main purpose of this paper is to establish a preliminary computer assisted simulation in prostate tumor cryosurgery. A radiologist and an urologist in a medical center in addition to the engineering specialist from the university participated in this interdisciplinary research program. The first step of this simulation protocol is to trim hundreds of two-dimensional medical imaging photos from a patient through the imaging reconstructive software into building a three-dimensional solid modeling. The image data for each patient can be obtained from the x-ray computed tomography (CT), or magnetic resonance imaging (MRI) in the imaging department of hospital. It has successfully built up the related knowledge to overcome the complicacy between the medical imaging modalities and engineering graphic solid modeling with high resolution. It is worthy to mention here that the present solid modeling of prostate can demonstrate the variable diameters and courses of the prostate urethra in vivo. The second step focuses on thermal calculation. So far, there has been no existing commercial software for the specific purpose of the bioheat transfer problem. Hence, user subroutines must be added to the existing commercial software to simulate the clinical situation of cryosurgery. For example, the occurrence of phase change during some specified temperature range and the latent heat of fusion are also incorporated into bio-heat transfer model. It has successfully incorporated bioheat transfer model into the software program to fit the reality in thermal medicine. The third step supplies the data and knowledge concerned with the position of a tumor and the related mechanism of metabolism of living tissue and vessels. The number of probes, the position of each probe, and the operating time of each probe will be explored to ensure a complete killing of the tumor tissue while saving as much healthy surrounding tissue as possible. In this study, the three-dimensional transient temperature distributions based on cryosurgery for prostate tumors have been performed for several cases to find the optimal operating conditions. Different cryoprobes with different freezing time are considered to find the temperature distribution. The simulation results for cryosurgery of prostate tumors will be supplied for practicing physicians as reference to greatly improve the effectiveness of cryosurgery.

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Panta Pazos, Rube´n. "Finding the Minimun of the Quadratic Functional in Variational Approach in Transport Theory Problems." In 16th International Conference on Nuclear Engineering. ASMEDC, 2008. http://dx.doi.org/10.1115/icone16-48479.

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In this work it is reviewed the variational approach for some Transport Problems. Let X be a convex domain in Rn, and V a compact set. For that, it is considered the following equation: ∂ψ∂t(x,v,t)+v·∇ψ(x,v,t)+h(x,μ)ψ(x,v,t)==∫Vk(x,v,v′)ψ(x,v′,t)dv′+q(x,v,t)(1) where x represents the spatial variable in a domain D, v an element of a compact set V, Ψ is the angular flux, h(x,v) the collision frequency, k(x,v,v’) the scattering kernel function and q(x,v) the source function. It is put the attention in the construction of the quadratic functional J which appears in variational approaches for transport theory (for example, the Vladimirov functional). Some properties of this functional in a proper functional framework, in order to determine the minimum for J are considered. First, the general formulation is studied. Then an algorithm is given for minimizing the functional J for two remarkable problems: spherical harmonic method and spectral collocation method. A program associated to this algorithm is worked in a computer algebraic system, and also was depeloped a version in a high level language.

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8

Kato, H., K. Uchida, Y. Okada, and T. Yamaguchi. "ANALYSIS OF HYPERCOAGULABILITY BY AUTOMATED FLUOROGENIC METHODS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643053.

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In order to detect hypercoagulable state due to the increase or decrease of coagulation factors and inhibitors concentrations or the presence of active coagulation factors or tissue factor in plasma, highly sensitive automated methods were developed using fluorogenic substrate for thrombin. Coagulability of human plasma was measured by mixing 3 yl of plasma with Thromborel S (TF), calcium and Boc-Val-Pro-Arg-MCA(MCA) (Fluorogenic PT, FPT). FPT of normal plasma was shortened by the addition of purified X or VII (Final conc. 1-5 U per ml), and of thrombin (0.3-1 ng) or Xa (10500 pg). Factors VII and X contents in plasma were measured by mixing 3 yl of diluted plasma with each factor deficient plasma, TF, calcium and MCA in which 10 %-800 % of each factor was quantitatively measured. TF and Xa were measured by mixing with XII or X deficient plasma, phospholipid, calcium and MCA. By this method, 5-500 pg of Xa or 1-1000 units of TF (assuming that one vial of Thromborel S contains 2,000,000 U TF per ml) was quantitatively measured. All the experiments were performed using a centrifugal autoanalyzer (Cobas Bio) with FIA module. The reaction time to reach 0.1 relative fluorescence was calculated by a computer using a program developed by us.These automated methods were applied to examine the hypercoagulability of plasmas from patients with cerebral infarction. Sixty five samples out of 75 showed shorter FPT than control plasma. Xa was detected with the conc. of 3-13 ng Xa per ml. FPT of patient plasmas correlated with Xa content (r=0.70) and X (r=0.63). Xa activity of patient plasma was eluted in the same peak as purified X on gel-filtration of Sephacryl S-200 column and completely inhibited by anti X rabbit IgG. Xa activity was also found in normal serum. The conventional PT or chromogenic PT methods are sensitive to hypocoagulable state but not to hypercoagulab le state. The present automated methods were proved to be sensitive to hypercoagulable state and demonstrated that the presence of Xa or the increase of X concentration in plasma contributes in part to the hypercoagulable state of cerebral infarction.

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9

Krishnaswami, P., and S. Ramaswamy. "Supercomputer-Based Sensitivity Analysis of Constrained Dynamic Systems." In ASME 1987 Design Technology Conferences. American Society of Mechanical Engineers, 1987. http://dx.doi.org/10.1115/detc1987-0019.

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Abstract Generalized design sensitivity analysis of constrained dynamic systems is a computationally intensive process that is well-suited for implementation on a modern supercomputer. A matrix oriented method for design sensitivity analysis, based on direct differentiation, is developed. An algorithm based on this development was implemented in a computer code which was then run on a Cray X-MP supercomputer. The implementation attempts to make full use of the vectorization capabilities of this machine. The numerical examples that were run on this implementation were compared with results presented in the literature in order to verify the program and to assess its computational performance. The results show that the use of supercomputers for performing design sensitivity analysis of dynamic systems using this method produces a dramatic reduction in the computing time; it is anticipated that this will make the optimization of very large-scale dynamic systems computationally viable.

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10

Iwaarden, Freek van, G. Philip, de Groot, and Bonno N. Bouma. "CULTURED HUMAN ENDOTHELIAL CELLS BIND AND INTERNALIZE HIGH MOLECULAR WEIGHT KININOGEN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644727.

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The presence of High Molecular Weight kininogen (HMWK) was demonstrated in cultured human endothelial cells (EC) by immunofluorescence techniques. Using an enzyme linked immunosorbent assay a concentration of 58 ng HMWK/10 cells was determined. Immunoprecipitation studies performed with lysed metabolically labelled endothelial cells and mono-specific antisera directed against HMWK suggested that HMWK is not synthesized by the endothelial cells. Endothelial cells cultured in the presence of HMWK-depleted serum did not contain HMWK. This, suggests that endothelial cells can internalize HMWK. Using 125I-HMWK it was demonstrated that cultured endothelial cells bind HMWK in a time-dependent, specific and saturable.way. The cells were found to internalize 125I-HMWK, since I-HMWK was detected in solubilized endothelial cells after the cell bound 125I-HMWK had been eluted with dextran sulphate.The binding of I-HMWK required the presence of zinc ions. Optimal binding of 125I-HMWK was observed at 50 μM Zn++ . Calcium ions inhibited the Zn++ dependent binding of 125I-HMWK |25EC. In the presence of 3 mM CaCl2 the total binding of 125I-HMWK was significantly decreased, and a .concentration of 200 μM Zn++ was Required for the binding of 125I-HMWK to thecells. Higher,. Ca concentrations did not further decrease the binding of 125I-HMWK. Analysis of tl^e binding data by the ligand computer program indicated 3.2 x 10 binding sites per cell for HMWK with a Kd of 35 nM at 50 μM ZnCl2 and 1 mM CaCl2. Specify binding of HMWK did also occur at physiological plasma Zn++ concentrations. Half maximal binding was observed at HMWK concentrations of ± 105 nM at 10 μM ZnCl2 and 45 nM at 25 μM ZnCl2. The HMWK binding sites were saturatecT at HMWK concentrations of 130 nM with 1.6 x 10 molecules of HMWK bound per cell and at 80 nM with 2.8 x 10 molecules of HMWK bound per cell at 10 and 25 pM ZnCl2 respectively. These results suggest that at physiological zinc, calcium and HMWK concentrations the HMWK binding sites on the endothelial cell are saturated. The presence of HMWK on the endothelial cell surface may play a role in the initiation of the intrinsic coagulation pathway. M ZnCl2 and 45 nM at 25 μM ZnCl2. The HMWK binding sites were saturatecT at HMWK concentrations of 130 nM with 1.6 x 10 molecules of HMWK bound per cell and at 80 nM with 2.8 x 10 molecules of HMWK bound per cell at 10 and 25 μM ZnCl2 respectively. These results suggest that at physiological zinc, calcium and HMWK concentrations the HMWK binding sites on the endothelial cell are saturated. The presence of HMWK on the endothelial cell surface may play a role in the initiation of the intrinsic coagulation pathway. M ZnCl2 and 45 nM at 25 μM ZnCl2. The HMWK binding sites were saturatecT at HMWK concentrations of 130 nM with 1.6 x 10 molecules of HMWK bound per cell and at 80 nM with 2.8 x 10 molecules of HMWK bound per cell at 10 and 25 μM ZnCl2 respectively. These results suggest that at physiological zinc, calcium and HMWK concentrations the HMWK binding sites on the endothelial cell are saturated. The presence of HMWK on the endothelial cell surface may play a role in the initiation of the intrinsic coagulation pathway. M ZnCl2 and 45 nM at 25 μM ZnCl2. The HMWK binding sites were saturatecT at HMWK concentrations of 130 nM with 1.6 x 10 molecules of HMWK bound per cell and at 80 nM with 2.8 x 10 molecules of HMWK bound per cell at 10 and 25 μM ZnCl2 respectively. These results suggest that at physiological zinc, calcium and HMWK concentrations the HMWK binding sites on the endothelial cell are saturated. The presence of HMWK on the endothelial cell surface may play a role in the initiation of the intrinsic coagulation pathway.M ZnCl2 and 45 nM at 25 μM ZnCl2. The HMWK binding sites were saturatecT at HMWK concentrations of 130 nM with 1.6 x 16 molecules of HMWK bound per cell and at 80 nM with 2.8 x 106 molecules of HMWK bound per cell at 10 and 25 μM ZnCl2 respectively. These results suggest that at physiological zinc, calcium and HMWK concentrations the HMWK binding sites on the endothelial cell are saturated. The presence of HMWK on the endothelial cell surface may play a role in the initiation of the intrinsic coagulation pathway.

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Reports on the topic "X/Motif (Computer program)"

1

Francis, Dorothy A. X-Ray Anthropometry Transformation Program for the Hewlett-Packard 9000/835 Computer. Fort Belvoir, VA: Defense Technical Information Center, May 1991. http://dx.doi.org/10.21236/ada291095.

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2

Etelaeniemi, V., P. Suortti, and W. Thomlinson. REFLECT: A computer program for the x-ray reflectivity of bent perfect crystals. Office of Scientific and Technical Information (OSTI), September 1989. http://dx.doi.org/10.2172/5480497.

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3

Braeuer, E., and W. Thomlinson. Experimental verification of ''photon'': A computer program for use in x-ray shielding calculations. Office of Scientific and Technical Information (OSTI), March 1987. http://dx.doi.org/10.2172/6874284.

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4

Pringle, G. J. Eddi: a Fortran Computer Program To Produce Correctedelectron - Microprobe Analyses of minerals using An Energy Dispersive X - Rayspectrometer. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1990. http://dx.doi.org/10.4095/127685.

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5

Pringle, G. J. Eddi: a Fortran Computer Program To Produce Corrected Microprobe Analyses of minerals using An Energy Dispersive X-ray Spectrometer. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1989. http://dx.doi.org/10.4095/130786.

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