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1

1946-, Barnes Peter J., ed. The Mechanism of action of Xanthines in respiratory disease. Royal Society of Medicine Services, 1988.

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2

Karl-Erik, Andersson, Persson C. G. A, and AB Draco, eds. Anti-asthma xanthines and adenosine: Proceedings of a symposium in Copenhagen, February 22-23, 1985. Excerpta Medica, 1985.

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3

Services, IBC Technical, ed. Xanthines: an update on their chemistry, pharmacology and therapeutics: Conference documentation : London, 1988. IBC TechnicalServices, 1988.

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4

1944-, Costello J. F., Piper Priscilla J, and Royal Society of Medicine (Great Britain). Respiratory Section., eds. Methylxanthines and phosphodiesterase inhibitors in the treatment of airways disease: The proceedings of a meeting held by the Respiratory Section of the Royal Society of Medicine, London, November 1993. Parthenon Pub. Group, 1994.

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5

International Workshop on Adenosine and Xanthine Derivatives (1984 Wiesbaden, Germany). Adenosine: Receptors and modulation of cell function : proceedings of the International Workshop on Adenosine and Xanthine derivatives. IRL Press, 1985.

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6

Nilson, G. The mountain vipers of the Middle East: The Vipera xanthina complex (Reptilia, Viperidae). Zoologisches Forschungsinstitut und Museum Alexander Koenig, 1986.

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7

Neish, William J. P. Xanthines and cancer. Aberdeen University Press, 1988.

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8

(Editor), K. E. Andersson, and C.G.A. Persson (Editor), eds. Anti-asthma Xanthines and Adenosine (Current clinical practice series). Elsevier, 1986.

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9

Neish, William J. P. Xanthines and Cancer: An Experimental Study of Tumour Inhibition. MacMillan Publishing Company, 1988.

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10

Xanthines and cancer: An experimental study of tumour inhibition. Aberdeen University Press, 1988.

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11

Zürich, Eidgenössische Technische Hochschule, ed. Extraction of xanthines and cocoa butter from cocoa beans with supercritical CO₂. 1993.

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12

Fredholm, Bertil B. Methylxanthines. Springer, 2010.

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13

Fredholm, Bertil B. Methylxanthines. Springer, 2016.

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14

Stevens, Helena Louise. Xanthias New BFF. Austin Macauley Publishers Ltd., 2021.

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15

Stefanovich, V. Pharmacology of Adenosine and Xanthine Derivatives. Irl Pr, 1985.

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16

Hicking, W., P. Leskovar, R. Hartung, A. Hesse, and D. Bach. Harnsäure-, Zystin-, Xanthin-Stein. Springer London, Limited, 2013.

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17

Menard, Cédric. Recettes et menus pour les coliques néphrétiques xanthiques. Books on Demand, 2021.

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18

Dalbeth, Nicola. Urate-lowering therapy agents. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198748311.003.0009.

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Xanthine oxidase (allopurinol or febuxostat) is considered first-line urate-lowering therapy. Combination therapy with uricosuric agents may be required. The choice of urate-lowering therapy is dictated by co-morbidities, particularly renal and hepatic impairment. Appropriate monitoring for drug adverse effects as well as serum urate to ensure targets are achieved is required.
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19

Gowan, Simon William Mac. Evaluation of the possible role of xanthine oxidase in the pathogenesis of acute pancreatitis. 1992.

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20

Rice, Pauline. From The Land Of Glee, Xanthie And Zaybar Make New Friends. Small World Publishing, 2001.

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21

Richette, Pascal. Principles of gout management. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0044.

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The general goals of gout therapy are to manage acute flares and to prevent recurrences and prevent or reverse the complications of urate deposition by lowering urate levels. The choice of drug should be made on the basis of the patient’s co-morbidities, other medications, and side effect profile. Treatment of flares can be achieved with non-steroidal anti-inflammatory drugs, colchicine, or corticosteroids (systemic or intra-articular). Interleukin-1 blockers could become an alternative in patients contraindicated for traditional anti-inflammatory agents. Lowering of urate levels below monosod
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22

Jacobs, Andreas Bernhard. Untersuchungen über den Einfluss von Xanthin und Xanthinoxidase und Al 1576 auf den Stoffwechsel von Rinderlinsen. 1989.

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23

Kang, Duk-Hee, and Mehmet Kanbay. Urate nephropathy. Edited by Adrian Covic. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0092.

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Gout is a disorder of purine metabolism, characterized by hyperuricaemia and urate crystal deposition within and around the joints. The recognition of increased comorbidity burden in patients with gout rendered it as a systemic disorder rather than simply a musculoskeletal condition. Gout nephropathy (also known as chronic uric acid nephropathy or urate nephropathy) is a form of chronic tubulointerstitial nephritis, induced by deposition of monosodium urate crystals in the distal collecting ducts and the medullary interstitium, associated with a secondary inflammatory reaction. Other renal his
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24

Dambrova, Maija. Discovery of N-Hydroxyguanidines As Novel Electron Acceptors of Xanthine Oxidase: Potential New Drugs for Treatment of Ischemia and Reperfusion Injury ... from the Faculty of Pharmacy, 217). Uppsala Universitet, 1999.

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25

Kock, Rüdiger. Entwicklung einer HPLC-Methode zur simultanen Bestimmung von Hypoxanthin, Xanthin, Harnsäure und Allantoin im Serum und ihre Anwendung bei Herzinfarktpatienten. 1991.

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26

(Contributor), WHO, ed. Coffee, Tea, Mate, Methylxanthines and Methylglyoxal (IARC Monographs on the Evaluation of Carcinogenic Risks to H). World Health Organisation, 1991.

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