Relevant bibliographies by topics / Xenobiotik

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Xenobiotik'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Xenobiotik"

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Hertz, R., and J. Bar−Tana. "The acylation of proteins by xenobiotic amphipathic carboxylic acids in cultured rat hepatocytes." Biochemical Journal 254, no. 1 (August 15, 1988): 39–44. http://dx.doi.org/10.1042/bj2540039.

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Three xenobiotic amphipathic carboxylates, namely MEDICA 16, nafenopin and bezafibrate, which differ remarkably in their hydrophobic backbones, were found to acylate membrane and cytosolic liver proteins in cultured rat hepatocytes. The acylation patterns observed were time- and dose-dependent, and the acylated residue consisted of the original xenobiotic. The acylation patterns generated by the three xenobiotic carboxylates included common proteins which were acylated by the three xenobiotics (e.g. proteins of 32, 52, 56 and 72 kDa) as well as unique proteins which were specifically acylated by the respective xenobiotics. The acylation of liver proteins by either MEDICA 16 or nafenopin remained unaffected under conditions where protein synthesis was completely inhibited by cycloheximide. Protein acylation thus offers a common mode of action of xenobiotic amphipathic carboxylates, which may, however, result in diverse xenobiotyl-protein adducts. The xenobiotyl-acylated proteins might be involved in triggering some of the biological effects exerted by xenobiotic amphipathic carboxylates employed as hypolipidaemic effectors, peroxisomal proliferators or preadipocyte convertors.
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Musolff, A., S. Leschik, M. T. Schafmeister, F. Reinstorf, G. Strauch, R. Krieg, and M. Schirmer. "Evaluation of xenobiotic impact on urban receiving waters by means of statistical methods." Water Science and Technology 62, no. 3 (August 1, 2010): 684–92. http://dx.doi.org/10.2166/wst.2010.930.

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Xenobiotics in urban receiving waters are an emerging problem. A sound knowledge of xenobiotic input, distribution and fate in the aquatic environment is a prerequisite for risk assessments. Methods to assess the impact of xenobiotics on urban receiving waters should address the diverse characteristics of the target compounds and the spatiotemporal variability of concentrations. Here, we present results from a one-year-monitoring program concerning concentrations of pharmaceuticals, additives from personal care products and industrial chemicals in an urban drainage catchment in untreated and treated wastewater, surface water and groundwater. Univariate and multivariate statistical methods were applied to characterize the xenobiotic concentrations. Correlation and principal component analysis revealed a pronounced pattern of xenobiotics in the surface water samples. The concentrations of several xenobiotics were characterized by a negative proportionality to the water temperature. Therefore, seasonal attenuation is assumed to be a major process influencing the measured concentrations. Moreover, dilution of xenobiotics the surface water was found to significantly influence the concentrations. These two processes control more the xenobiotic occurrence in the surface water than the less pronounced concentration pattern in the wastewater sources. For the groundwater samples, we assume that foremost attenuation processes lead to the found differentiation of xenobiotics.
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Adrir, Mutia Syarifah, Ratna Stia Dewi, and Ajeng Arum Sari. "Aktivitas Enzimatik Isolat Trametes spp. dari Kebun Raya Baturraden dalam Pewarna Batik dengan Variasi Konsentrasi Indigosol Blue Glukosa." BioEksakta : Jurnal Ilmiah Biologi Unsoed 2, no. 2 (July 25, 2020): 174. http://dx.doi.org/10.20884/1.bioe.2020.2.2.1810.

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Indigosol Blue merupakan salah satu zat warna sintetik Antraquinon yang digunakan sebagai pewarna biru pada industri pencelupan tekstil dan bersifat rekalsitran dan non-biodegradable, sehingga tidak mudah rusak oleh perlakuan kimia maupun fotolitik. Isolat Trametes sp. diyakini memiliki kemampuan mentransformasi komponen pewarna melalui mekanisme degradasi enzimatik. Trametes sp. mampu menghasilkan enzim ekstraseluler ligninolitik yang dapat mendegradasi komponen xenobiotik dalam limbah pewarna indigosol menjadi bentuk yang tidak toksik di lingkungan. Penelitian bertujuan untuk mengetahui kemampuan tiga isolat uji dalam menghasilkan enzim dalam pewarna Indigosol Blue pada konsentrasi glukosa berbeda serta mengetahui isolat dengan konsentrasi glukosa optimum yang memiliki aktivitas enzim terbaik dalam pewarna Indigosol Blue. Pengukuran aktivitas enzimatik dilakukan dengan metode spektrofotometri. Hasil penelitian menunjukkan bahwa isolat-isolat uji dapat menghasilkan enzim dalam pewarna Indigosol Blue pada konsentrasi glukosa berbeda. Aktivitas enzim pada masing-masing perlakuan berbeda-beda dan menunjukkan hasil yang signifikan. Data uji lanjut memperlihatkan bahwa isolat Trametes sp. strain A memiliki aktivitas enzim terbaik dalam pewarna Indigosol Blue dengan konsentrasi glukosa 0,5%. Penelitian juga menunjukkan bahwa konsentrasi glukosa di atas 0.5% dapat menghambat aktivitas lakase, sehingga aktivitas lakase dalam zat pewarna rendah. Kata kunci: enzim ligninolitik, fungi, glukosa, Indigosol Blue, Trametes sp.
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Sugrue, Elena, Carol J. Hartley, Colin Scott, and Colin J. Jackson. "The Evolution of New Catalytic Mechanisms for Xenobiotic Hydrolysis in Bacterial Metalloenzymes." Australian Journal of Chemistry 69, no. 12 (2016): 1383. http://dx.doi.org/10.1071/ch16426.

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An increasing number of bacterial metalloenzymes have been shown to catalyse the breakdown of xenobiotics in the environment, while others exhibit a variety of promiscuous xenobiotic-degrading activities. Several different evolutionary processes have allowed these enzymes to gain or enhance xenobiotic-degrading activity. In this review, we have surveyed the range of xenobiotic-degrading metalloenzymes, and discuss the molecular and catalytic basis for the development of new activities. We also highlight how our increased understanding of the natural evolution of xenobiotic-degrading metalloenzymes can be been applied to laboratory enzyme design.
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Afschar, Sonita, Janne M. Toivonen, Julia Marianne Hoffmann, Luke Stephen Tain, Daniela Wieser, Andrew John Finlayson, Yasmine Driege, et al. "Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila." Proceedings of the National Academy of Sciences 113, no. 5 (January 19, 2016): 1321–26. http://dx.doi.org/10.1073/pnas.1515137113.

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Lifespan of laboratory animals can be increased by genetic, pharmacological, and dietary interventions. Increased expression of genes involved in xenobiotic metabolism, together with resistance to xenobiotics, are frequent correlates of lifespan extension in the nematode worm Caenorhabditis elegans, the fruit fly Drosophila, and mice. The Green Theory of Aging suggests that this association is causal, with the ability of cells to rid themselves of lipophilic toxins limiting normal lifespan. To test this idea, we experimentally increased resistance of Drosophila to the xenobiotic dichlordiphenyltrichlorethan (DDT), by artificial selection or by transgenic expression of a gene encoding a cytochrome P450. Although both interventions increased DDT resistance, neither increased lifespan. Furthermore, dietary restriction increased lifespan without increasing xenobiotic resistance, confirming that the two traits can be uncoupled. Reduced activity of the insulin/Igf signaling (IIS) pathway increases resistance to xenobiotics and extends lifespan in Drosophila, and can also increase longevity in C. elegans, mice, and possibly humans. We identified a nuclear hormone receptor, DHR96, as an essential mediator of the increased xenobiotic resistance of IIS mutant flies. However, the IIS mutants remained long-lived in the absence of DHR96 and the xenobiotic resistance that it conferred. Thus, in Drosophila IIS mutants, increased xenobiotic resistance and enhanced longevity are not causally connected. The frequent co-occurrence of the two traits may instead have evolved because, in nature, lowered IIS can signal the presence of pathogens. It will be important to determine whether enhanced xenobiotic metabolism is also a correlated, rather than a causal, trait in long-lived mice.
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Šíma, Martin, I. Netíková, and O. Slanař. "Pregnane Xenobiotic Receptors and Their Effect on Drug Elimination from the Organism." Prague Medical Report 114, no. 4 (2013): 205–13. http://dx.doi.org/10.14712/23362936.2014.9.

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Nuclear receptors are intracellular proteins which, having been activated by their more or less specific ligands, regulate (usually increase) the transcription of target genes. They thus participate in a regulation of a number of physiologic functions. Some of them – especially pregnane xenobiotic receptors – serve primarily as protection of the organism from the xenobiotic intoxication. This is because many xenobiotics activate their function which consists in increasing the gene expression of enzymes involved in the metabolism of xenobiotics and detoxication drug transporters. Clarification of these mechanisms enabled the understanding of the substance of many drug-drug interactions observed in the clinical practice. Polymorphism of the nuclear receptors appears to be one of the causes of the interindividual variability in response to drug administration.
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Klaassen, Curtis D. "Xenobiotic Transporters: Another Protective Mechanism for Chemicals." International Journal of Toxicology 21, no. 1 (January 2002): 7–12. http://dx.doi.org/10.1080/10915810252825975.

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Xenobiotic transporters are responsible for the uptake of some chemicals into cells, and extremely important for the export of chemicals out of cells. A number of families of xenobiotic transporters have been cloned the last few years. Some microsomal enzyme inducers will enhance the plasma disappearance and biliary excretion of some xenobiotics that are not biotransformed in the intact animal, as well as in isolated hepatocytes. This is due to an up-regulation of xenobiotic transporters. As a result, some microsomal enzyme inducers will enhance the elimination and decrease the toxicity of some chemicals by enhanced transport.
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Hatagima, Ana. "Genetic polymorphisms and metabolism of endocrine disruptors in cancer susceptibility." Cadernos de Saúde Pública 18, no. 2 (April 2002): 357–77. http://dx.doi.org/10.1590/s0102-311x2002000200002.

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Epidemiological studies have estimated that approximately 80% of all cancers are related to environmental factors. Individual cancer susceptibility can be the result of several host factors, including differences in metabolism, DNA repair, altered expression of tumor suppressor genes and proto-oncogenes, and nutritional status. Xenobiotic metabolism is the principal mechanism for maintaining homeostasis during the body's exposure to xenobiotics. The balance of xenobiotic absorption and elimination rates in metabolism can be important in the prevention of DNA damage by chemical carcinogens. Thus the ability to metabolize and eliminate xenobiotics can be considered one of the body's first protective mechanisms. Variability in individual metabolism has been related to the enzymatic polymorphisms involved in activation and detoxification of chemical carcinogens. This paper is a contemporary literature review on genetic polymorphisms involved in the metabolism of endocrine disruptors potentially related to cancer development.
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Tanaka, Atsushi, Patrick SC Leung, and M. Eric Gershwin. "Environmental basis of primary biliary cholangitis." Experimental Biology and Medicine 243, no. 2 (January 2018): 184–89. http://dx.doi.org/10.1177/1535370217748893.

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Autoimmunity is a consequence of both genetic and environmental factors, occurring in genetically susceptible hosts with environmental triggers. While genome-wide association studies have revealed a number of susceptible genes contributing to etiology, the environmental triggers remain poorly understood. Primary biliary cholangitis, formally known as primary biliary cirrhosis, is considered a model autoimmune disease for which our group has extensively evaluated environmental factors involved in its etiology. Bacterial infection and xenobiotics have been proposed as candidate environmental factors that may explain tolerance breakdown and production of primary biliary cholangitis-specific antimitochondrial autoantibodies. Large-scale case-control studies have consistently detected an association of primary biliary cholangitis with urinary tract infections caused by Escherichia coli, as E. coli PDC-E2 is molecularly similar to human PDC-E2, the immunodominant target of AMAs. Another bacterium of interest is Novosphingobium aromaticivorans, a ubiquitous xenobiotic-metabolizing bacterium that produces lipoylated proteins, which are highly reactive with sera from primary biliary cholangitis patients. Regarding xenobiotics, case-control studies have suggested that frequent use of nail polish is associated with an increased susceptibility to primary biliary cholangitis. We found that 2-octynamide, the conjugate derived from 2-octynoic acid present in cosmetics, lipsticks, and some chewing gums, was unique in both its quantitative structure–activity relationship analysis and reactivity with primary biliary cholangitis sera. 2-nonyamide is another xenobiotic that also has the optimal chemical structure for xenobiotic modification of the PDC-E2 epitope, as demonstrated by the enhanced epitope recognition with AMA-positive PBC sera. Moreover, we found that C57BL/6 mice immunized with 2-octynoic acid-BSA possess many of the features characteristic to primary biliary cholangitis. Impact statement Autoimmunity is believed to develop in genetically susceptible hosts with triggers from the environment. Researchers have recently demonstrated that bacteria and xenobiotics commonly present in our environment are potential triggers of tolerance breakdown against autoantigens and autoimmunity, particularly in primary biliary cholangitis (PBC). The link between xenobiotics and PBC has been further confirmed with the establishment of PBC model mice by immunizing mice with xenobiotics.
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Todoruk, Tiona R., and Cooper H. Langford. "Sorption of a Xenobiotic Contaminant in Clean and Petroleum-Contaminated Soil: Roles of Water and Xenobiotic Size." Environmental Chemistry 3, no. 2 (2006): 124. http://dx.doi.org/10.1071/en05082.

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Environmental Context.Soil uptake of xenobiotics (e.g. pesticides) can be a complex phenomenon where it is useful to distinguish readily reversible sorption from longer-term retention. A scheme for doing this using fluorescence detection is presented here, along with application to uptake of a model compound in clean and oil-contaminated soils. Both the wetting of the soil and the size of the xenobiotic seem to be important. The present data concern uptake. Desorption is expected to exhibit dependencies on similar factors. The data have implications for understanding persistence. Abstract.Description of sorption of xenobiotics (e.g. pesticides) into soils requires identification of at least two kinetic components. In the present work, the distinction between ‘labile’ (readily reversible) and ‘non-labile’ (not reversible) uptake was extended, introducing a fluorescence-based method using 9-anthracenepropionic acid as a probe molecule. Study of clean, oil-contaminated wettable, and water-repellent oil-contaminated soils has given new perspectives into the role that water plays in xenobiotic uptake. Non-labile uptake is unimportant in the water-repellent soils; however, non-labile components are observed in both clean and wettable oil-contaminated samples, supporting earlier suggestions that water plays a role in non-labile uptake processes. A soil pre-exposed to water exhibited different labile sorption behavior from one where xenobiotic was added simultaneously with water to an air-dried soil. The comparatively rapid non-labile component of uptake (3 days) of 9-anthracenepropanoic acid by a clean soil contrasted with much longer times in earlier studies of 2,4-D and atrazine. This pointed to another factor influencing the sorption phenomenon. Literature data supports a suggestion that the non-labile component of xenobiotic sorption may be more strongly influenced by the size of the xenobiotic than by the structure (e.g. polarity) of the xenobiotic or soil composition.
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Dissertations / Theses on the topic "Xenobiotik"

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Píšťková, Veronika. "Studium průběhu degradace xenobiotik a biologicky aktivních látek s využitím oxidu titaničitého." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2012. http://www.nusl.cz/ntk/nusl-216860.

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Heterogenous photocatalysis using titanium dioxide seems to be a promising method for disposal xenobiotics from the environment. The aim of this diploma thesis is the study of degradation of selected xenobiotics and biologically active substrances applying this method. Theoretical part of diploma thesis deals with the principals of heterogenous photocatalysis by means of a semiconductor TiO2 and the examples of its possible application are mentioned too. The compounds which could be appropriate for a study of degradation were selected from the group of pharmaceuticals and pesticides. The properties of target substances and their environmental impact were described. Furthermore, a bibliographic search focused on the possibilities of their analytical determination was conducted. The experimental part of the thesis describes the experiments with photocatalyst in a form of powder as well as with immobilized photocatalyst in thin layer on a carrier. Identification and quantification of analytes was realized by high performance liquid chromatography with mass spectrometic detection.
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Dobre, Cristina. "Vitamin E vid prostatacancer." Thesis, Umeå universitet, Farmakologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-121398.

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Sammanfattning Vitamin E är en substans med antioxidanta egenskaper, ett fettlösligt vitamin som kan finnas i naturliga källor såsom vegetabiliska oljor, ägg, grönsaker, spannmål, frukter,kött men också i syntetisk form. I dagsläget är vitamin E också tillgängligt som kosttillskott och används förebyggande och/eller vid behandling av sjukdomar som kardiovaskulära sjukdomar, arterioskleros, diabetes mellitius samt olika former av cancer. Vid intag av vitamin E kan oxidativ stress minskas vilket produceras av fria radikaler (t.ex. joniserande strålning, giftiga föreningar från luft, vatten, mat) som drabbar celler och på det sättet förebyggs och fördröjs uppkomst av sjukdomar. Utöver sin antioxidant effekt och är vitamin E involverat i immunförsvaret, cellsignalering,genreglering samt andra metaboliska processer. Dessa egenskaper har gjort av vitaminE är en intressant kandidat till utredning vid prostatacancer (adenocarcinom), som är den vanligaste tumörformen i Sverige hos män över 50-års ålder. Denna litteraturstudie har för syfte att undersöka det empiriska stödet för tesen omvitamin E kan ha en förebyggande effekt mot prostatacancer och vilka risker som finns vid intag av vitamin E vid prostatacancer. Tidigare forskning har visat att det har enantioxidativ inverkan på kroppens organ och det har därför funnits en tro på att den kan hjälpa förebygga prostatacancer. Litteraturstudien bygger på originalartiklar framförallt från PubMed, Socialstyrelse hemsidan, WebMd, olika medicinska böcker och i Google med sökord som: vitamin E, prostatacancer, tokoferol och prostatacancer,oxidative stress, antioxidant, androgen metabolism och vitamin E, prostatacancer ocharv, androgen och vitamin E. Resultatet av studierna visar att det inte finns ett entydigt empiriskt stöd för att vitaminE (tokoferol) har en förebyggande effekt mot prostatacancer. Vissa studier visar ett stöd för att det finns en förebyggande effekt, andra visar att det inte finns ett stöd och en visar en signifikant ökad risk för prostatacancer vid intag av tokoferol. Prostatacancer kan inte förebyggas med vitamin E (tokoferol) enligt forskningsresultaten i denna studie. Vidare forskning krävs för att se om det kan finnas kombinationer med t.ex. selen för att öka effektiviteten för att förebygga prostatacancer.
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Mravcová, Ludmila. "Využití separačních technik na bázi plynové a kapalinové chromatografie s různým typem detektorů pro stanovení biologicky aktivních látek a vybraných xenobiotik." Doctoral thesis, Vysoké učení technické v Brně. Fakulta chemická, 2011. http://www.nusl.cz/ntk/nusl-233330.

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This work deals with the using and application of separation techniques for analysis of polymers degradation and polycyclic aromatic hydrocarbons. Thereby this work is separated to two special parts. In the first part, the degradation properties of synthetic biopolymers based on lactic acid, gylcolic acid and poly(ethyleneglycol) PLGA-PEG-PLGA and ITA-PLGA-PEG-PLGA-ITA (modified by itaconic acid) were studied. These copolymers (firstly their thermosensitive hydrogels) should be used for therapy of fractures in orthopedy (as adhesives). Therefore, the sol-gel and gel-sol phase diagrams were determinated for selected samples of copolymers. The samples forming gel at 37 C was used for other study. Polymer samples were depredated in phosphate buffer at 37°C. The degradation process of physical hydrogels was described by the decrease of molecular weight and the increase of concentration lactic acid and glycolic acid in phosphate buffer. The obtained results confirmed that the degradation of polymer modified by itaconic acid is faster process than no modified polymer and polymers with lower ratio PLGA/PEG degrade also faster than lower ration PLGA/PEG. The influence of pH it was also tested. The rate of degradation of polymers was follow pH 4,0
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Turková, Lucie. "Porovnání sekvenčních variant genů pro biotransformační enzymy u různých typů karcinomů." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2017. http://www.nusl.cz/ntk/nusl-295694.

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Xenobiotic biotransformation process and its capacity is crucial for xenobiotic chemicals elimination that may cause damage toward cell structures. The effectiveness of the enzymes included in this process depends on the gene variants that encodes them. The aim of this work was to compare certain polymorphisms of selected genes between cases and control groups. Studied polymorphisms were null genotypes of the glutathione S-transferase gene M1 and T1 and the insertion of TA dinucleotide in the promotor region of UDP-glucuronosyl transferase 1A1. The number of cases group was six included patients with colorectal, lung, prostate, breast, pancreatic and head and neck cancer. Total number of analysed individuals was 1 118 for cancer cases and 470 for healthy controls. The control group was divided into two groups, the first one was called general and the second one was called special included healthy individuals with no cancer history in their closest family members. Gilbert syndrome (GS) is caused by homozygous insertion of the TA dinucleotide in the TATA box of the gene UGT1A1 and it causes elevated bilirubin levels. Bilirubin is a potent antioxidant in human body, so the aim was to attest its protective effect toward cancer. We expected lower frequency of GS as a protective factor in the cases groups compared with controls. This hypothesis was confirmed in the breast cancer group (GS frequency 10,0 %) and pancreatic cancer group (GS frequency 11,1 %). In the general and special control groups the frequency of GS was 16,0 % and 15,4 % respectively. Although the other case groups show lower frequency of GS, the results weren´t statistically significant. Null GSTM1 genotype was observed with 50,4 % frequency in the general control groups and with 55,3 % frequency in the special control group. Neither the one of the cases groups hasn´t showed significantly lower percentage of null genotype. Despite expectation we observed statistically significant lower frequency of null genotype in the group of lung and pancreatic cancer group (37,4 % and 39,3 % respectively). According to this study, we can say that the lack of glutathione S-transferase M1 activity is not a risk factor for cancer development. Null genotype of GSTT1 wasn´t identified in both control groups at all. In case groups of breast and prostate cancer, there was only one individual carrying the null GSTT1 genotype. Statistically significant higher frequency of this polymorphism was observed in patients with colorectal cancer (9,7 %), lung cancer (17,2 %), pancreatic cancer (3,0 %) and head and neck cancer (15,9 %). In these groups the lack of glutathion S-transferase T1 activity might be considered as risk factor for cancer development. Nevertheless, for further verification it needs to take more investigation in this field, especially enlarge the number of patient in the case groups of head and neck, lung and pancreatic cancer.
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Adams, Samuel E. "Molecular similarity and xenobiotic metabolism." Thesis, University of Cambridge, 2010. https://www.repository.cam.ac.uk/handle/1810/225225.

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MetaPrint2D, a new software tool implementing a data-mining approach for predicting sites of xenobiotic metabolism has been developed. The algorithm is based on a statistical analysis of the occurrences of atom centred circular fingerprints in both substrates and metabolites. This approach has undergone extensive evaluation and been shown to be of comparable accuracy to current best-in-class tools, but is able to make much faster predictions, for the first time enabling chemists to explore the effects of structural modifications on a compound’s metabolism in a highly responsive and interactive manner. MetaPrint2D is able to assign a confidence score to the predictions it generates, based on the availability of relevant data and the degree to which a compound is modelled by the algorithm. In the course of the evaluation of MetaPrint2D a novel metric for assessing the performance of site of metabolism predictions has been introduced. This overcomes the bias introduced by molecule size and the number of sites of metabolism inherent to the most commonly reported metrics used to evaluate site of metabolism predictions. This data mining approach to site of metabolism prediction has been augmented by a set of reaction type definitions to produce MetaPrint2D-React, enabling prediction of the types of transformations a compound is likely to undergo and the metabolites that are formed. This approach has been evaluated against both historical data and metabolic schemes reported in a number of recently published studies. Results suggest that the ability of this method to predict metabolic transformations is highly dependent on the relevance of the training set data to the query compounds. MetaPrint2D has been released as an open source software library, and both MetaPrint2D and MetaPrint2D-React are available for chemists to use through the Unilever Centre for Molecular Science Informatics website.
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Smith, Nicola Jane. "Modulation of xenobiotic metabolism by garlic." Thesis, Liverpool John Moores University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247381.

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Tyzack, Jonathan David. "Prediction of cytochrome P450 xenobiotic metabolism." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708289.

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Stříteský, Luboš. "Využití oxidačních procesů (AOP) pro odstraňování mikropolutantů." Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2013. http://www.nusl.cz/ntk/nusl-226161.

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This thesis deals with advanced oxidation processes (AOPs) and it’s use for removal of micropollutants from wastewater. The first chapter explains the need AOPs, water quality, pollution and substances that are present in the water. Further, the first chapter outlines approach of the current legislation to micropollutants. The second chapter explains the theory and principle of operation of AOPs. This chapter is divided into two sections. The first section describes AOPs, which were tested at selected WWTP. In the second section, there are described some other AOPs. The third chapter is a literature retrieval of AOPs dealing with the removal of micropollutants. This chapter is focused on the removal of hormones by AOPs using ozone-based AOPs. The fourth chapter describes the actual testing of selected AOPs. The chapter describes selected WWTP, pilot-scale AOP unit and test results. In the last chapter there is designed and described full-scale AOP tertiary unit for removing of micropollutants. The last chapter also contains economic analysis of the proposed tertiary unit.
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Munro, D. Ross. "Biphasic fermentation of xenobiotics." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq20681.pdf.

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Haselden, John Neil. "The synthesis and metabolism of xenobiotic acylglycerols." Thesis, Imperial College London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243552.

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Books on the topic "Xenobiotik"

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Dočkal, Pavel. Metody testů akutní toxicity a biodegradability xenobiotik. Praha: Výzkumný ústav vodohospodářský ve Státním zemědělském nakl., 1988.

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Albert, Adrien. Xenobiosis. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-017-5377-7.

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Paulson, Gaylord D., John Caldwell, David H. Hutson, and Julius J. Menn, eds. Xenobiotic Conjugation Chemistry. Washington, DC: American Chemical Society, 1986. http://dx.doi.org/10.1021/bk-1986-0299.

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Mitchell, Stephen Charles. Xenobiotic metabolism and pharmacogenetics. Birmingham: University of Birmingham, 1997.

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Connell, D. W. Bioaccumulation of xenobiotic compounds. Boca Raton, Fla: CRC Press, 1990.

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Finley, John W., and Daniel E. Schwass, eds. Xenobiotic Metabolism: Nutritional Effects. Washington, D.C.: American Chemical Society, 1985. http://dx.doi.org/10.1021/bk-1985-0277.

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Castaneda, Saul F., and Mauro L. Emerson. Xenobiotics: New research. Hauppauge, N.Y: Nova Science Publishers, 2011.

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Smith, David J., William H. Gingerich, and Maria G. Beconi-Barker, eds. Xenobiotics in Fish. Boston, MA: Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4703-7.

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Arora, Pankaj Kumar, ed. Microbial Metabolism of Xenobiotic Compounds. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7462-3.

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Microbial degradation of xenobiotics. Berlin: Springer-Verlag Berlin Heidelberg, 2011.

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Book chapters on the topic "Xenobiotik"

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Gooch, Jan W. "Xenobiotic." In Encyclopedic Dictionary of Polymers, 932. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_15126.

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Arndt, T. "Xenobiotika." In Lexikon der Medizinischen Laboratoriumsdiagnostik, 1–2. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-49054-9_3333-1.

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Arndt, T. "Xenobiotika." In Springer Reference Medizin, 2518–19. Berlin, Heidelberg: Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_3333.

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Cecchi, Dario, and Sheref S. Mansy. "Xenobiotic Life." In Synthetic Biology, 337–57. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-22708-5_10.

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Albert, Adrien. "Introduction to the concept: Xenobiosis." In Xenobiosis, 1–3. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-017-5377-7_1.

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Albert, Adrien. "Introduction to Part Three: Poisons as foreign substances." In Xenobiosis, 215–38. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-017-5377-7_10.

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Albert, Adrien. "Poisons absorbed through lungs or skin." In Xenobiosis, 239–61. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-017-5377-7_11.

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Albert, Adrien. "Poisons absorbed through eating or drinking." In Xenobiosis, 262–76. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-017-5377-7_12.

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Albert, Adrien. "Some foreign substances with consequences for public policy." In Xenobiosis, 277–326. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-017-5377-7_13.

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Albert, Adrien. "Introduction to Part One: Foods as foreign substances." In Xenobiosis, 7–17. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-017-5377-7_2.

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Conference papers on the topic "Xenobiotik"

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STANKEVIČIŪTĖ, Jolanta, Solveiga Marija BARKAUSKAITĖ, and Gediminas BRAZAITIS. "DETECTION OF XENOBIOTIC SUBSTANCES IN MUTE SWANS’ (CYGNUS OLOR) BLOOD." In Rural Development 2015. Aleksandras Stulginskis University, 2015. http://dx.doi.org/10.15544/rd.2015.064.

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During recent years the attention towards the effects of xenobiotic substances on wild nature has been steadily increasing. Literature reviews have revealed that active hormone-disintegrating substances might affect the reproduction of some wild animal species. Research shows anomalies of reproduction and development in various animal groups such as birds, fish, invertebrates and reptiles. Species inhabiting water and its surroundings cause the highest concern. Due to insufficient baseline information it is difficult to determine the extent of the problem in these wild populations on an ecological scale. The research described in this article is the first attempt to analyse xenobiotic substances and evaluate possible accumulation of pharmaceuticals in animals higher up in the food chain in Lithuania. This research tests new methods for to analyse for xenobiotics substances, which might be used in the future. Blood samples of 7 swans were examined using liquid chromatography, however, no xenobiotics were detected. Negative results do not eliminate the necessity for further investigate of larger samples, other species or to search for non-pharmaceutical xenobiotics.
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MCSHAN, D. C., M. UPDADHAYAYA, and I. SHAH. "SYMBOLIC INFERENCE OF XENOBIOTIC METABOLISM." In Proceedings of the Pacific Symposium. WORLD SCIENTIFIC, 2003. http://dx.doi.org/10.1142/9789812704856_0051.

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Kucherenko, S. V. "XENOBIOTICS ATTACK! WHAT TO DO?" In STATE AND DEVELOPMENT PROSPECTS OF AGRIBUSINESS. DSTU-PRINT, 2020. http://dx.doi.org/10.23947/interagro.2020.1.178-180.

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Xenobiotics - substances alien to the body - have become a major problem, since they negatively affect human health. They can directly affect, disrupting vital functions, and can form various metabolites in the body due to transformation. But the main danger of xenobiotics is their bioaccumulation. There are many studies on how to prevent the harmful effects of xenobiotics. This article discusses the main routes of ingestion of these foreign.
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Sheikh-Bahaei, Shahab, and C. Anthony Hunt. "Simulating plausible mechanisms for changing hepatic xenobiotic clearance patterns." In 2010 Winter Simulation Conference - (WSC 2010). IEEE, 2010. http://dx.doi.org/10.1109/wsc.2010.5679128.

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White, Kristin L., Thomas A. Sellers, Robert A. Vierkant, Catherine Phelan, Julie M. Cunningham, Joellen M. Schildkraut, Andy Berchuck, et al. "Abstract 914: Xenobiotic metabolizing SNPs and ovarian cancer risk." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-914.

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Watanabe, Masaji, and Fusako Kawai. "Solutions of inverse problems for biodegradation of xenobiotic polymers." In PROCEEDINGS OF THE 7TH SEAMS UGM INTERNATIONAL CONFERENCE ON MATHEMATICS AND ITS APPLICATIONS 2015: Enhancing the Role of Mathematics in Interdisciplinary Research. AIP Publishing LLC, 2016. http://dx.doi.org/10.1063/1.4940851.

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Earley, R. "228. Perspectives on Human Exposure to Xenobiotics." In AIHce 2000. AIHA, 2000. http://dx.doi.org/10.3320/1.2763563.

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Prager, H.-M., C. Lukas, M. Blaszkewicz, T. Kadhum, JG Hengstler, S. Selinski, and K. Golka. "367 Prognosis of occupational bladder cancer and polymorphic xenobiotic metabolising enzymes." In 32nd Triennial Congress of the International Commission on Occupational Health (ICOH), Dublin, Ireland, 29th April to 4th May 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/oemed-2018-icohabstracts.1149.

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Putluri, Nagireddy, Vihas T. Vasu, Ali Shojaie, Gagan Singh Thangjam, Shaiju K. Vareed, Vasanta Putluri, Charles Butler, et al. "Abstract A52: Metabolomic profiling reveals impaired xenobiotic metabolism in bladder cancer." In Abstracts: AACR International Conference on the Science of Cancer Health Disparities‐‐ Sep 30-Oct 3, 2010; Miami, FL. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1055-9965.disp-10-a52.

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Schmidt, Sarah L., and Jong-In Han. "Contributions of Xenobiotic-Degrading Bacterial Endophytes to the Field of Phytoremediation." In GeoCongress 2008. Reston, VA: American Society of Civil Engineers, 2008. http://dx.doi.org/10.1061/40970(309)65.

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Reports on the topic "Xenobiotik"

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Gschwend, Philip M., and Ken O. Buesseler. Xenobiotic Organic Compound Cycling in Coastal Waters. Fort Belvoir, VA: Defense Technical Information Center, September 1997. http://dx.doi.org/10.21236/ada634638.

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Boyd, S. A., and J. M. Tiedje. Dechlorination of Aromatic Xenobiotic Compounds by Anaerobic Microorganisms. Fort Belvoir, VA: Defense Technical Information Center, July 1988. http://dx.doi.org/10.21236/ada203642.

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Khandan, N. N. Microbial Toxicity of Non-Uniform Mixtures of Xenobiotic Chemicals. Fort Belvoir, VA: Defense Technical Information Center, June 1997. http://dx.doi.org/10.21236/ada329750.

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Nisbet, Roger M., Russell J. Schmitt, and William G. Wilson. Mathematical Models Relating Effects of Xenobiotic Substances on Individuals and Populations. Fort Belvoir, VA: Defense Technical Information Center, September 1997. http://dx.doi.org/10.21236/ada635054.

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Stohs, Sidney J. Common Pathways in the Toxicity of Structurally Diverse Xenobiotics. Fort Belvoir, VA: Defense Technical Information Center, March 1999. http://dx.doi.org/10.21236/ada368838.

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Bigsby, Robert M. Novel Mechanisms of Tumor Promoter Activity by Estrogenic Xenobiotics. Fort Belvoir, VA: Defense Technical Information Center, April 2000. http://dx.doi.org/10.21236/ada392984.

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Hicks, R. J., and P. Van Voris. Review and evaluation of the effects of xenobiotic chemicals on microorganisms in soil. [139 references]. Office of Scientific and Technical Information (OSTI), February 1988. http://dx.doi.org/10.2172/5406358.

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Link, S. O., R. J. Fellows, D. A. Cataldo, J. G. Droppo, and P. Van Voris. Estimation of aerial deposition and foliar uptake of xenobiotics: Assessment of current models. Office of Scientific and Technical Information (OSTI), October 1987. http://dx.doi.org/10.2172/5632579.

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Riviere, J. E., N. A. Monteiro-Riviere, and K. F. Bowman. Development of In Vitro Isolated Perfused Porcine Skin Flaps for Study of Percutaneous Absorption of Xenobiotics. Fort Belvoir, VA: Defense Technical Information Center, June 1987. http://dx.doi.org/10.21236/ada204615.

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Riviere, J. E., M. P. Carver, N. A. Monteiro-Riviere, and K. F. Bowman. Development of In Vitro Isolated Perfused Porcine Skin Flaps for Study of Percutaneous Absorption of Xenobiotics. Fort Belvoir, VA: Defense Technical Information Center, November 1986. http://dx.doi.org/10.21236/ada198960.

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