Academic literature on the topic 'Xenobiotik'

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Journal articles on the topic "Xenobiotik"

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Hertz, R., and J. Bar−Tana. "The acylation of proteins by xenobiotic amphipathic carboxylic acids in cultured rat hepatocytes." Biochemical Journal 254, no. 1 (1988): 39–44. http://dx.doi.org/10.1042/bj2540039.

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Three xenobiotic amphipathic carboxylates, namely MEDICA 16, nafenopin and bezafibrate, which differ remarkably in their hydrophobic backbones, were found to acylate membrane and cytosolic liver proteins in cultured rat hepatocytes. The acylation patterns observed were time- and dose-dependent, and the acylated residue consisted of the original xenobiotic. The acylation patterns generated by the three xenobiotic carboxylates included common proteins which were acylated by the three xenobiotics (e.g. proteins of 32, 52, 56 and 72 kDa) as well as unique proteins which were specifically acylated
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Musolff, A., S. Leschik, M. T. Schafmeister, et al. "Evaluation of xenobiotic impact on urban receiving waters by means of statistical methods." Water Science and Technology 62, no. 3 (2010): 684–92. http://dx.doi.org/10.2166/wst.2010.930.

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Xenobiotics in urban receiving waters are an emerging problem. A sound knowledge of xenobiotic input, distribution and fate in the aquatic environment is a prerequisite for risk assessments. Methods to assess the impact of xenobiotics on urban receiving waters should address the diverse characteristics of the target compounds and the spatiotemporal variability of concentrations. Here, we present results from a one-year-monitoring program concerning concentrations of pharmaceuticals, additives from personal care products and industrial chemicals in an urban drainage catchment in untreated and t
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Adrir, Mutia Syarifah, Ratna Stia Dewi, and Ajeng Arum Sari. "Aktivitas Enzimatik Isolat Trametes spp. dari Kebun Raya Baturraden dalam Pewarna Batik dengan Variasi Konsentrasi Indigosol Blue Glukosa." BioEksakta : Jurnal Ilmiah Biologi Unsoed 2, no. 2 (2020): 174. http://dx.doi.org/10.20884/1.bioe.2020.2.2.1810.

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Indigosol Blue merupakan salah satu zat warna sintetik Antraquinon yang digunakan sebagai pewarna biru pada industri pencelupan tekstil dan bersifat rekalsitran dan non-biodegradable, sehingga tidak mudah rusak oleh perlakuan kimia maupun fotolitik. Isolat Trametes sp. diyakini memiliki kemampuan mentransformasi komponen pewarna melalui mekanisme degradasi enzimatik. Trametes sp. mampu menghasilkan enzim ekstraseluler ligninolitik yang dapat mendegradasi komponen xenobiotik dalam limbah pewarna indigosol menjadi bentuk yang tidak toksik di lingkungan. Penelitian bertujuan untuk mengetahui kema
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Sugrue, Elena, Carol J. Hartley, Colin Scott, and Colin J. Jackson. "The Evolution of New Catalytic Mechanisms for Xenobiotic Hydrolysis in Bacterial Metalloenzymes." Australian Journal of Chemistry 69, no. 12 (2016): 1383. http://dx.doi.org/10.1071/ch16426.

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An increasing number of bacterial metalloenzymes have been shown to catalyse the breakdown of xenobiotics in the environment, while others exhibit a variety of promiscuous xenobiotic-degrading activities. Several different evolutionary processes have allowed these enzymes to gain or enhance xenobiotic-degrading activity. In this review, we have surveyed the range of xenobiotic-degrading metalloenzymes, and discuss the molecular and catalytic basis for the development of new activities. We also highlight how our increased understanding of the natural evolution of xenobiotic-degrading metalloenz
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Afschar, Sonita, Janne M. Toivonen, Julia Marianne Hoffmann, et al. "Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila." Proceedings of the National Academy of Sciences 113, no. 5 (2016): 1321–26. http://dx.doi.org/10.1073/pnas.1515137113.

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Lifespan of laboratory animals can be increased by genetic, pharmacological, and dietary interventions. Increased expression of genes involved in xenobiotic metabolism, together with resistance to xenobiotics, are frequent correlates of lifespan extension in the nematode worm Caenorhabditis elegans, the fruit fly Drosophila, and mice. The Green Theory of Aging suggests that this association is causal, with the ability of cells to rid themselves of lipophilic toxins limiting normal lifespan. To test this idea, we experimentally increased resistance of Drosophila to the xenobiotic dichlordipheny
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Šíma, Martin, I. Netíková, and O. Slanař. "Pregnane Xenobiotic Receptors and Their Effect on Drug Elimination from the Organism." Prague Medical Report 114, no. 4 (2013): 205–13. http://dx.doi.org/10.14712/23362936.2014.9.

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Nuclear receptors are intracellular proteins which, having been activated by their more or less specific ligands, regulate (usually increase) the transcription of target genes. They thus participate in a regulation of a number of physiologic functions. Some of them – especially pregnane xenobiotic receptors – serve primarily as protection of the organism from the xenobiotic intoxication. This is because many xenobiotics activate their function which consists in increasing the gene expression of enzymes involved in the metabolism of xenobiotics and detoxication drug transporters. Clarification
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Klaassen, Curtis D. "Xenobiotic Transporters: Another Protective Mechanism for Chemicals." International Journal of Toxicology 21, no. 1 (2002): 7–12. http://dx.doi.org/10.1080/10915810252825975.

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Xenobiotic transporters are responsible for the uptake of some chemicals into cells, and extremely important for the export of chemicals out of cells. A number of families of xenobiotic transporters have been cloned the last few years. Some microsomal enzyme inducers will enhance the plasma disappearance and biliary excretion of some xenobiotics that are not biotransformed in the intact animal, as well as in isolated hepatocytes. This is due to an up-regulation of xenobiotic transporters. As a result, some microsomal enzyme inducers will enhance the elimination and decrease the toxicity of som
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Hatagima, Ana. "Genetic polymorphisms and metabolism of endocrine disruptors in cancer susceptibility." Cadernos de Saúde Pública 18, no. 2 (2002): 357–77. http://dx.doi.org/10.1590/s0102-311x2002000200002.

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Epidemiological studies have estimated that approximately 80% of all cancers are related to environmental factors. Individual cancer susceptibility can be the result of several host factors, including differences in metabolism, DNA repair, altered expression of tumor suppressor genes and proto-oncogenes, and nutritional status. Xenobiotic metabolism is the principal mechanism for maintaining homeostasis during the body's exposure to xenobiotics. The balance of xenobiotic absorption and elimination rates in metabolism can be important in the prevention of DNA damage by chemical carcinogens. Thu
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Tanaka, Atsushi, Patrick SC Leung, and M. Eric Gershwin. "Environmental basis of primary biliary cholangitis." Experimental Biology and Medicine 243, no. 2 (2018): 184–89. http://dx.doi.org/10.1177/1535370217748893.

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Autoimmunity is a consequence of both genetic and environmental factors, occurring in genetically susceptible hosts with environmental triggers. While genome-wide association studies have revealed a number of susceptible genes contributing to etiology, the environmental triggers remain poorly understood. Primary biliary cholangitis, formally known as primary biliary cirrhosis, is considered a model autoimmune disease for which our group has extensively evaluated environmental factors involved in its etiology. Bacterial infection and xenobiotics have been proposed as candidate environmental fac
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Todoruk, Tiona R., and Cooper H. Langford. "Sorption of a Xenobiotic Contaminant in Clean and Petroleum-Contaminated Soil: Roles of Water and Xenobiotic Size." Environmental Chemistry 3, no. 2 (2006): 124. http://dx.doi.org/10.1071/en05082.

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Environmental Context.Soil uptake of xenobiotics (e.g. pesticides) can be a complex phenomenon where it is useful to distinguish readily reversible sorption from longer-term retention. A scheme for doing this using fluorescence detection is presented here, along with application to uptake of a model compound in clean and oil-contaminated soils. Both the wetting of the soil and the size of the xenobiotic seem to be important. The present data concern uptake. Desorption is expected to exhibit dependencies on similar factors. The data have implications for understanding persistence. Abstract.Desc
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Dissertations / Theses on the topic "Xenobiotik"

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Píšťková, Veronika. "Studium průběhu degradace xenobiotik a biologicky aktivních látek s využitím oxidu titaničitého." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2012. http://www.nusl.cz/ntk/nusl-216860.

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Heterogenous photocatalysis using titanium dioxide seems to be a promising method for disposal xenobiotics from the environment. The aim of this diploma thesis is the study of degradation of selected xenobiotics and biologically active substrances applying this method. Theoretical part of diploma thesis deals with the principals of heterogenous photocatalysis by means of a semiconductor TiO2 and the examples of its possible application are mentioned too. The compounds which could be appropriate for a study of degradation were selected from the group of pharmaceuticals and pesticides. The prope
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Dobre, Cristina. "Vitamin E vid prostatacancer." Thesis, Umeå universitet, Farmakologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-121398.

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Sammanfattning Vitamin E är en substans med antioxidanta egenskaper, ett fettlösligt vitamin som kan finnas i naturliga källor såsom vegetabiliska oljor, ägg, grönsaker, spannmål, frukter,kött men också i syntetisk form. I dagsläget är vitamin E också tillgängligt som kosttillskott och används förebyggande och/eller vid behandling av sjukdomar som kardiovaskulära sjukdomar, arterioskleros, diabetes mellitius samt olika former av cancer. Vid intag av vitamin E kan oxidativ stress minskas vilket produceras av fria radikaler (t.ex. joniserande strålning, giftiga föreningar från luft, vatten, mat)
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Mravcová, Ludmila. "Využití separačních technik na bázi plynové a kapalinové chromatografie s různým typem detektorů pro stanovení biologicky aktivních látek a vybraných xenobiotik." Doctoral thesis, Vysoké učení technické v Brně. Fakulta chemická, 2011. http://www.nusl.cz/ntk/nusl-233330.

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This work deals with the using and application of separation techniques for analysis of polymers degradation and polycyclic aromatic hydrocarbons. Thereby this work is separated to two special parts. In the first part, the degradation properties of synthetic biopolymers based on lactic acid, gylcolic acid and poly(ethyleneglycol) PLGA-PEG-PLGA and ITA-PLGA-PEG-PLGA-ITA (modified by itaconic acid) were studied. These copolymers (firstly their thermosensitive hydrogels) should be used for therapy of fractures in orthopedy (as adhesives). Therefore, the sol-gel and gel-sol phase diagrams were det
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Turková, Lucie. "Porovnání sekvenčních variant genů pro biotransformační enzymy u různých typů karcinomů." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2017. http://www.nusl.cz/ntk/nusl-295694.

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Xenobiotic biotransformation process and its capacity is crucial for xenobiotic chemicals elimination that may cause damage toward cell structures. The effectiveness of the enzymes included in this process depends on the gene variants that encodes them. The aim of this work was to compare certain polymorphisms of selected genes between cases and control groups. Studied polymorphisms were null genotypes of the glutathione S-transferase gene M1 and T1 and the insertion of TA dinucleotide in the promotor region of UDP-glucuronosyl transferase 1A1. The number of cases group was six included patien
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Adams, Samuel E. "Molecular similarity and xenobiotic metabolism." Thesis, University of Cambridge, 2010. https://www.repository.cam.ac.uk/handle/1810/225225.

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MetaPrint2D, a new software tool implementing a data-mining approach for predicting sites of xenobiotic metabolism has been developed. The algorithm is based on a statistical analysis of the occurrences of atom centred circular fingerprints in both substrates and metabolites. This approach has undergone extensive evaluation and been shown to be of comparable accuracy to current best-in-class tools, but is able to make much faster predictions, for the first time enabling chemists to explore the effects of structural modifications on a compound’s metabolism in a highly responsive and interactive
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Smith, Nicola Jane. "Modulation of xenobiotic metabolism by garlic." Thesis, Liverpool John Moores University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247381.

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Tyzack, Jonathan David. "Prediction of cytochrome P450 xenobiotic metabolism." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708289.

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Stříteský, Luboš. "Využití oxidačních procesů (AOP) pro odstraňování mikropolutantů." Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2013. http://www.nusl.cz/ntk/nusl-226161.

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This thesis deals with advanced oxidation processes (AOPs) and it’s use for removal of micropollutants from wastewater. The first chapter explains the need AOPs, water quality, pollution and substances that are present in the water. Further, the first chapter outlines approach of the current legislation to micropollutants. The second chapter explains the theory and principle of operation of AOPs. This chapter is divided into two sections. The first section describes AOPs, which were tested at selected WWTP. In the second section, there are described some other AOPs. The third chapter is a lite
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Munro, D. Ross. "Biphasic fermentation of xenobiotics." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq20681.pdf.

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Haselden, John Neil. "The synthesis and metabolism of xenobiotic acylglycerols." Thesis, Imperial College London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243552.

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Books on the topic "Xenobiotik"

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Dočkal, Pavel. Metody testů akutní toxicity a biodegradability xenobiotik. Výzkumný ústav vodohospodářský ve Státním zemědělském nakl., 1988.

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Albert, Adrien. Xenobiosis. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-017-5377-7.

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Paulson, Gaylord D., John Caldwell, David H. Hutson, and Julius J. Menn, eds. Xenobiotic Conjugation Chemistry. American Chemical Society, 1986. http://dx.doi.org/10.1021/bk-1986-0299.

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Mitchell, Stephen Charles. Xenobiotic metabolism and pharmacogenetics. University of Birmingham, 1997.

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Connell, D. W. Bioaccumulation of xenobiotic compounds. CRC Press, 1990.

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Finley, John W., and Daniel E. Schwass, eds. Xenobiotic Metabolism: Nutritional Effects. American Chemical Society, 1985. http://dx.doi.org/10.1021/bk-1985-0277.

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Castaneda, Saul F., and Mauro L. Emerson. Xenobiotics: New research. Nova Science Publishers, 2011.

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Smith, David J., William H. Gingerich, and Maria G. Beconi-Barker, eds. Xenobiotics in Fish. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4703-7.

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Arora, Pankaj Kumar, ed. Microbial Metabolism of Xenobiotic Compounds. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7462-3.

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Microbial degradation of xenobiotics. Springer-Verlag Berlin Heidelberg, 2011.

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Book chapters on the topic "Xenobiotik"

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Gooch, Jan W. "Xenobiotic." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_15126.

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Arndt, T. "Xenobiotika." In Lexikon der Medizinischen Laboratoriumsdiagnostik. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-49054-9_3333-1.

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Arndt, T. "Xenobiotika." In Springer Reference Medizin. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_3333.

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Cecchi, Dario, and Sheref S. Mansy. "Xenobiotic Life." In Synthetic Biology. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-22708-5_10.

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Albert, Adrien. "Introduction to the concept: Xenobiosis." In Xenobiosis. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-017-5377-7_1.

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Albert, Adrien. "Introduction to Part Three: Poisons as foreign substances." In Xenobiosis. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-017-5377-7_10.

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Albert, Adrien. "Poisons absorbed through lungs or skin." In Xenobiosis. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-017-5377-7_11.

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Albert, Adrien. "Poisons absorbed through eating or drinking." In Xenobiosis. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-017-5377-7_12.

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Albert, Adrien. "Some foreign substances with consequences for public policy." In Xenobiosis. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-017-5377-7_13.

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Albert, Adrien. "Introduction to Part One: Foods as foreign substances." In Xenobiosis. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-017-5377-7_2.

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Conference papers on the topic "Xenobiotik"

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STANKEVIČIŪTĖ, Jolanta, Solveiga Marija BARKAUSKAITĖ, and Gediminas BRAZAITIS. "DETECTION OF XENOBIOTIC SUBSTANCES IN MUTE SWANS’ (CYGNUS OLOR) BLOOD." In Rural Development 2015. Aleksandras Stulginskis University, 2015. http://dx.doi.org/10.15544/rd.2015.064.

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During recent years the attention towards the effects of xenobiotic substances on wild nature has been steadily increasing. Literature reviews have revealed that active hormone-disintegrating substances might affect the reproduction of some wild animal species. Research shows anomalies of reproduction and development in various animal groups such as birds, fish, invertebrates and reptiles. Species inhabiting water and its surroundings cause the highest concern. Due to insufficient baseline information it is difficult to determine the extent of the problem in these wild populations on an ecolog
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MCSHAN, D. C., M. UPDADHAYAYA, and I. SHAH. "SYMBOLIC INFERENCE OF XENOBIOTIC METABOLISM." In Proceedings of the Pacific Symposium. WORLD SCIENTIFIC, 2003. http://dx.doi.org/10.1142/9789812704856_0051.

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Kucherenko, S. V. "XENOBIOTICS ATTACK! WHAT TO DO?" In STATE AND DEVELOPMENT PROSPECTS OF AGRIBUSINESS. DSTU-PRINT, 2020. http://dx.doi.org/10.23947/interagro.2020.1.178-180.

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Xenobiotics - substances alien to the body - have become a major problem, since they negatively affect human health. They can directly affect, disrupting vital functions, and can form various metabolites in the body due to transformation. But the main danger of xenobiotics is their bioaccumulation. There are many studies on how to prevent the harmful effects of xenobiotics. This article discusses the main routes of ingestion of these foreign.
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Sheikh-Bahaei, Shahab, and C. Anthony Hunt. "Simulating plausible mechanisms for changing hepatic xenobiotic clearance patterns." In 2010 Winter Simulation Conference - (WSC 2010). IEEE, 2010. http://dx.doi.org/10.1109/wsc.2010.5679128.

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White, Kristin L., Thomas A. Sellers, Robert A. Vierkant, et al. "Abstract 914: Xenobiotic metabolizing SNPs and ovarian cancer risk." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-914.

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Watanabe, Masaji, and Fusako Kawai. "Solutions of inverse problems for biodegradation of xenobiotic polymers." In PROCEEDINGS OF THE 7TH SEAMS UGM INTERNATIONAL CONFERENCE ON MATHEMATICS AND ITS APPLICATIONS 2015: Enhancing the Role of Mathematics in Interdisciplinary Research. AIP Publishing LLC, 2016. http://dx.doi.org/10.1063/1.4940851.

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Earley, R. "228. Perspectives on Human Exposure to Xenobiotics." In AIHce 2000. AIHA, 2000. http://dx.doi.org/10.3320/1.2763563.

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Prager, H.-M., C. Lukas, M. Blaszkewicz, et al. "367 Prognosis of occupational bladder cancer and polymorphic xenobiotic metabolising enzymes." In 32nd Triennial Congress of the International Commission on Occupational Health (ICOH), Dublin, Ireland, 29th April to 4th May 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/oemed-2018-icohabstracts.1149.

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Putluri, Nagireddy, Vihas T. Vasu, Ali Shojaie, et al. "Abstract A52: Metabolomic profiling reveals impaired xenobiotic metabolism in bladder cancer." In Abstracts: AACR International Conference on the Science of Cancer Health Disparities‐‐ Sep 30-Oct 3, 2010; Miami, FL. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1055-9965.disp-10-a52.

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Schmidt, Sarah L., and Jong-In Han. "Contributions of Xenobiotic-Degrading Bacterial Endophytes to the Field of Phytoremediation." In GeoCongress 2008. American Society of Civil Engineers, 2008. http://dx.doi.org/10.1061/40970(309)65.

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Reports on the topic "Xenobiotik"

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Gschwend, Philip M., and Ken O. Buesseler. Xenobiotic Organic Compound Cycling in Coastal Waters. Defense Technical Information Center, 1997. http://dx.doi.org/10.21236/ada634638.

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Boyd, S. A., and J. M. Tiedje. Dechlorination of Aromatic Xenobiotic Compounds by Anaerobic Microorganisms. Defense Technical Information Center, 1988. http://dx.doi.org/10.21236/ada203642.

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Khandan, N. N. Microbial Toxicity of Non-Uniform Mixtures of Xenobiotic Chemicals. Defense Technical Information Center, 1997. http://dx.doi.org/10.21236/ada329750.

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Nisbet, Roger M., Russell J. Schmitt, and William G. Wilson. Mathematical Models Relating Effects of Xenobiotic Substances on Individuals and Populations. Defense Technical Information Center, 1997. http://dx.doi.org/10.21236/ada635054.

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Stohs, Sidney J. Common Pathways in the Toxicity of Structurally Diverse Xenobiotics. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada368838.

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Bigsby, Robert M. Novel Mechanisms of Tumor Promoter Activity by Estrogenic Xenobiotics. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada392984.

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Hicks, R. J., and P. Van Voris. Review and evaluation of the effects of xenobiotic chemicals on microorganisms in soil. [139 references]. Office of Scientific and Technical Information (OSTI), 1988. http://dx.doi.org/10.2172/5406358.

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Link, S. O., R. J. Fellows, D. A. Cataldo, J. G. Droppo, and P. Van Voris. Estimation of aerial deposition and foliar uptake of xenobiotics: Assessment of current models. Office of Scientific and Technical Information (OSTI), 1987. http://dx.doi.org/10.2172/5632579.

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Riviere, J. E., N. A. Monteiro-Riviere, and K. F. Bowman. Development of In Vitro Isolated Perfused Porcine Skin Flaps for Study of Percutaneous Absorption of Xenobiotics. Defense Technical Information Center, 1987. http://dx.doi.org/10.21236/ada204615.

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Riviere, J. E., M. P. Carver, N. A. Monteiro-Riviere, and K. F. Bowman. Development of In Vitro Isolated Perfused Porcine Skin Flaps for Study of Percutaneous Absorption of Xenobiotics. Defense Technical Information Center, 1986. http://dx.doi.org/10.21236/ada198960.

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