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1

Cheng, Wen-Yu, Shih-Lu Wu, Chien-Yun Hsiang, et al. "Relationship Between San-Huang-Xie-Xin-Tang and Its Herbal Components on the Gene Expression Profiles in HepG2 Cells." American Journal of Chinese Medicine 36, no. 04 (2008): 783–97. http://dx.doi.org/10.1142/s0192415x08006235.

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Traditional Chinese medicine (TCM) has been used for thousands of years. Most Chinese herbal formulae consist of several herbal components and have been used to treat various diseases. However, the mechanisms of most formulae and the relationship between formulae and their components remain to be elucidated. Here we analyzed the putative mechanism of San-Huang-Xie-Xin-Tang (SHXXT) and defined the relationship between SHXXT and its herbal components by microarray technique. HepG2 cells were treated with SHXXT or its components and the gene expression profiles were analyzed by DNA microarray. Ge
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2

Friedemann, Thomas, Udo Schumacher, Yi Tao, Alexander Kai-Man Leung, and Sven Schröder. "Neuroprotective Activity of Coptisine fromCoptis chinensis(Franch)." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/827308.

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Coptis chinensisrhizomes (CR) are one important ingredient of traditional Chinese herbal formulas such as San-Huang-Xie-Xin-Tang which is used for treatment of cardiovascular and neurodegenerative diseases. Recent studies suggest that the extract of CR might be a potential therapeutic agent for amelioration of neurological disorders associated with oxidative stress. In the present study we aimed at revealing the main active compound(s) of the CR extract and at investigating the mechanism of action. Four main alkaloids of the CR extract (berberine, coptisine, jatrorrhizine, and palmatine) were
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3

Tang, Haoran, Feng Xie, Yue Zhang, and Shidong Jia. "Abstract 1049: Liquid biopsy-based comprehensive genomic profiling reveal mutational landscape in advanced breast cancer." Cancer Research 83, no. 7_Supplement (2023): 1049. http://dx.doi.org/10.1158/1538-7445.am2023-1049.

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Abstract Introduction: Breast cancer is the most common malignancy worldwide in females, with more than 2.26 million new cases and 680 thousand of deaths in 2020. Advanced breast cancer is characterized by complicated genomic landscape and requires comprehensive genomic profiling. However, tissue biopsy is hard to get in patients with recurrent metastasis. Meanwhile, limited studies have been reported to use liquid biopsy and were not capable of reporting gene copy number loss. Here we reported a comprehensive genomic profiling study in advanced breast cancer patients using liquid biopsy. Meth
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4

Tang, Haoran, Feng Xie, Yue Zhang, and Shidong Jia. "Abstract 5582: Liquid biopsy-based comprehensive genomic profiling reveal mutational landscape in real-world patients with unresectable NSCLC." Cancer Research 83, no. 7_Supplement (2023): 5582. http://dx.doi.org/10.1158/1538-7445.am2023-5582.

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Abstract Introduction: NSCLC accounts for more than 80% of all lung cancer, and has been shown for clinical benefits from targeted therapies, according to tests of multiple genes, such as EGFR, KRAS, ALK, ERBB2. Previous studies revealed molecular characteristics and responses of targeted therapies in NSCLC. However, most studies used tissue biopsies. There is increasing interest to characterize the molecular profile of NSCLC through liquid biopsy. Hence, here we report a comprehensive genomic profiling study in unresectable NSCLC patients using liquid biopsy. Methods: The prospective study is
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5

Tang, Haoran, Feng Xie, Yue Zhang, and Yutao Feng. "Abstract 5889: Combined cfDNA and cfRNA enhanced gene fusion detection and drug resistance mechanism insights in mCRPC through combined cfDNA and cfRNA assays profiling." Cancer Research 85, no. 8_Supplement_1 (2025): 5889. https://doi.org/10.1158/1538-7445.am2025-5889.

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Abstract Background: Metastatic castration-resistant prostate cancer (mCRPC) is a complex disease characterized by distinct molecular features related to genomic instability and selective treatment pressures. Cell-free DNA and RNA (cfDNA and cfRNA) found in blood offer potential for disease diagnosis, monitoring, and interrogation of resistance mechanisms by detecting genomic alterations from tumors. Here, we introduce comprehensive cfDNA and cfRNA assays to profile the genomic landscape in mCRPC patients for the purposes of disease diagnosis and monitoring. Methods: In this retrospective stud
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6

Shimizu, Masahiro, Tomonori Ichikawa, and Koki Tsuchikane. "Ionic Liquid As an Electrolyte Solvent for Proton Rechargeable Batteries." ECS Meeting Abstracts MA2024-02, no. 9 (2024): 1364. https://doi.org/10.1149/ma2024-0291364mtgabs.

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The diversity of carrier ions in electrochemical devices has attracted much attention to the use of protons.1−3 However, the narrow potential window of acid-based aqueous solutions typically used as proton conductors limits the operation of active materials.4 In this work, we examined the applicability of ionic liquids consisting of bis(trifluoromethanesulfonyl)amide (TFSA−) combined with N-propyl-N-methylpyrrolidinium (Pyr1,3 +) or 1-ethyl-3-methylimidazolium (EMI+), as the electrolytes. Raman spectroscopic measurements revealed that protons undergo coordination by TFSA− to form anionic compl
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7

Tang, Haoran, Cancan Jia, Feng Xie, et al. "Abstract 2410: Comparative genomic profiling of unresectable NSCLC patients in the U.S. and China using a globally harmonized liquid biopsy assay platform." Cancer Research 84, no. 6_Supplement (2024): 2410. http://dx.doi.org/10.1158/1538-7445.am2024-2410.

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Abstract Background: Non-Small Cell Lung Cancer (NSCLC), accounting for over 80% of all lung cancers, benefits from targeted therapies based on genetic tests like EGFR, KRAS, ALK, and ERBB2. While prior studies focused on molecular characteristics through tissue biopsies, limited research has explored NSCLC molecular profiles via liquid biopsy, especially across different human races. This study presents a comprehensive genomic profiling analysis of unresectable NSCLC patients in the U.S. and China, using a globally harmonized liquid biopsy assay. Methods: As part of Predicine's Phoenix Progra
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8

Weng, JingRong, JinXin Lin, YuMo Xie, et al. "Abstract 6006: RNA m6A methylation relay the oncogenic flow from DNA methylationto gene expression of ANKRD13B." Cancer Research 83, no. 7_Supplement (2023): 6006. http://dx.doi.org/10.1158/1538-7445.am2023-6006.

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Abstract Background: Colorectal cancer (CRC) is one of the most common causes of cancer-related death in the world. More comprehensive studies of key molecular alterations in CRC progression were urgent. DNA methylation promotes tumor progression. However, the mechanism of the ANKRD13 gene methylation that drives colorectal cancer evolution remains largely unknown. This was the first study focused on the role of ANKRD13 and the hypermethylated mechanisms in colorectal cancer. Methods: Chi-Square tests were utilized to the comparison of the baseline characteristics of patients with hypomethylat
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9

Belmontes, Brian, Katherine Slemmons, Siyuan Liu, et al. "Abstract B177: The discovery and preclinical characterization of AMG 193, a first-in-class MTA-cooperative PRMT5 inhibitor with broad activity against MTAP-null cancers." Molecular Cancer Therapeutics 22, no. 12_Supplement (2023): B177. http://dx.doi.org/10.1158/1535-7163.targ-23-b177.

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Abstract Homozygous deletion of the methylthioadenosine phosphorylase (MTAP) gene occurs in approximately 15% of all cancers due to its proximity to the commonly deleted tumor suppressor gene CDKN2A. Elevated methylthioadenosine (MTA) levels, driven by loss of MTAP, compete with the methyl donor S-adenosylmethionine (SAM) for binding to protein arginine N-methyltransferase 5 (PRMT5), placing the methyltransferase in a hypomorphic state, and vulnerable to further PRMT5 inhibition. The screening of a DNA-encoded library, designed to identify small molecules that preferentially bind to PRMT5 in t
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10

Liu, Xiaoran, Yaxin Liu, Cancan Jia, et al. "Abstract 1752: Comprehensive genomic profiling of advanced breast cancer subtypes: Insights from liquid biopsy analysis and implications for personalized therapies." Cancer Research 84, no. 6_Supplement (2024): 1752. http://dx.doi.org/10.1158/1538-7445.am2024-1752.

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Abstract Background: Breast cancer stands as the most prevalent malignancy affecting women’s health. The disease consists of three subtypes, including hormone receptor (HR) positive, HER2-positive, and triple-negative breast cancer (TNBC). In recent years, the advent of targeted therapies such as PI3K inhibitors has significantly improved the prognosis of breast cancer patients. However, the detection of relevant molecular markers, such as PIK3CA mutations, relies on tissue samples, which imposes limitations on the clinical application of these therapies. Consequently, this study presents a co
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Gan, Shuang, Haoran Tang, Feng Xie, Yue Zhang, and Hang Dong. "Abstract 6611: Genome-wide cfDNA fragmentomics combined with machine learning enhance non-invasive prostate cancer detection." Cancer Research 85, no. 8_Supplement_1 (2025): 6611. https://doi.org/10.1158/1538-7445.am2025-6611.

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Abstract The liquid biopsy approach focusing on DNA molecules offers a promising non-invasive method for prostate cancer diagnosis. Next-generation sequencing (NGS) of targeted gene panels is widely used for detecting somatic mutations but is limited by confounding clonal hematopoietic variants and narrow genome coverage. We propose a solution that encompasses genome-wide DNA fragmentation features for tumor fragment evaluation. This study collected plasma samples from 209 patients with prostate cancer and 49 healthy individuals as controls. Cell-free DNA (cfDNA) was extracted and tested using
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Shi, Qiong, Ting Zhang, Julia Kalashova, et al. "Abstract LB_C10: An orally available small molecule inhibitor for synthetic lethal targeting of MYC expressing tumors." Molecular Cancer Therapeutics 22, no. 12_Supplement (2023): LB_C10. http://dx.doi.org/10.1158/1535-7163.targ-23-lb_c10.

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Abstract The potential for synthetic lethality occurs when the same oncogenic events that promote carcinogenesis, also create vulnerabilities for cancer cells. Targeting cancers with these vulnerabilities, but not resident normal tissues, is the promise of synthetic lethal therapies. The compound LC30 is a potent and orally bioavailable compound that is synthetic lethal with deregulated MYC. No off-target liabilities have been demonstrated by kinome and safety profiling and long-term treatment is well tolerated by rodents and canines. LC30 is active against a wide spectrum of cell line xenogra
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13

Liao, Hao, Jianxin Zhong, Xiaoran Liu, et al. "Abstract 3238: Prognostic significance of ctDNA tumor fraction quantification in advanced HR-positive breast cancer." Cancer Research 85, no. 8_Supplement_1 (2025): 3238. https://doi.org/10.1158/1538-7445.am2025-3238.

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Abstract Introduction: Hormone receptor (HR)-positive breast cancer is the most common breast cancer subtype worldwide. While treatments with CDK4/6 inhibitors and endocrine therapies like aromatase inhibitors (AIs) have improved patient outcomes, the risk of disease progression persists. This study employs circulating tumor DNA (ctDNA) Next-Generation Sequencing (NGS) assays to profile gene variations and quantify tumor fraction in patients with advanced HR-positive breast cancer, aiming to identify relevant gene biomarkers and enhance patient management. Methods: In this retrospective study,
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14

Zhang, Yilan, Kai Jiang, Xiaokang Xu та ін. "Abstract 7119: Clinic-ready Polθ inhibitor SYX1097 suppresses solid tumors in vivo". Cancer Research 84, № 6_Supplement (2024): 7119. http://dx.doi.org/10.1158/1538-7445.am2024-7119.

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Abstract A large fraction of tumors with BRCA1 or BRCA2 mutations only have weak responses to PARP inhibitor (PARPi) treatment, and often develop PARPi resistance. To address these challenges, we have developed SYX1097, a selective and potent oral Polθ inhibitor as a single agent or in combination with PARPi for treating tumors with BRCA mutations. Both Polθ and PARP1 play key roles in microhomology-mediated end joining for DNA double-strand repair and in single-strand DNA gap filling during DNA replication. Using in vitro cellular assays and in vivo animal models, we show that SYX1097 alone o
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15

Tang, Haoran, Cancan Jia, Feng Xie, et al. "Abstract 5015: Genomic profiling of colorectal cancer - insights from liquid biopsy comparisons between U.S. and China cohorts." Cancer Research 84, no. 6_Supplement (2024): 5015. http://dx.doi.org/10.1158/1538-7445.am2024-5015.

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Abstract Background: Molecular characteristics play a pivotal role in cancer diagnosis, treatment selection, and disease monitoring across various tumor types. While previous research has elucidated the molecular classification of colorectal cancer using tissue NGS, limited investigation has explored the molecular profile of colorectal cancer through liquid biopsy, especially across diverse human races. This study presents a comprehensive genomic profiling analysis of colorectal cancer patients, using a globally harmonized liquid biopsy assay to compare patient cohorts from both the U.S. and C
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16

Dong, Hang, Shuang Gan, Haoran Tang, Yue Zhang, and Feng Xie. "Abstract 4111: Whole-genome methylation profiling enhances cancer detection and tumor fraction quantification in liquid biopsies." Cancer Research 85, no. 8_Supplement_1 (2025): 4111. https://doi.org/10.1158/1538-7445.am2025-4111.

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Abstract Circulating tumor DNA (ctDNA) is a critical biomarker for non-invasive cancer diagnosis, prognosis, and therapeutic monitoring. However, accurately quantifying ctDNA content in liquid biopsy samples remains challenging due to its low abundance and interference from non-tumor DNA. Current approaches, such as targeted sequencing and mutation-based quantification, are limited by their dependence on known mutations and reduced sensitivity to low ctDNA fractions. Next-generation sequencing (NGS)-based methylation profiling offers a promising alternative by leveraging the distinct methylati
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17

Tang, Haoran, Cancan Jia, Feng Xie, et al. "Abstract P5-04-18: Clinical Validation of an Ultra-Sensitive ctDNA NGS Assay in HR-Positive, HER2-Negative Breast Cancer Patients." Clinical Cancer Research 31, no. 12_Supplement (2025): P5–04–18—P5–04–18. https://doi.org/10.1158/1557-3265.sabcs24-p5-04-18.

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Abstract Introduction: Breast cancer remains the most common cancer diagnosis among women worldwide, with the majority of cases being hormone receptor (HR)-positive and HER2-negative. Although endocrine therapies have significantly improved patient outcomes, the risk of disease progression persists, sometimes even during the initial treatment phases. Current diagnostic techniques lack the sensitivity needed for patients with low tumor fractions and circulating tumor DNA (ctDNA) shedding in the early stages of disease or during early disease progression. This study presents the clinical validat
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18

Tang, Haoran, Feng Xie, Yue Zhang, and Shidong Jia. "Abstract 2197: Comparative genomic profiling and disease monitoring in unresectable gastric and colon cancer." Cancer Research 83, no. 7_Supplement (2023): 2197. http://dx.doi.org/10.1158/1538-7445.am2023-2197.

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Abstract Introduction: Molecular characteristics have significant clinical values in cancer distinguishing, treatment selection, and disease monitoring across large numbers of tumors. Previous studies have revealed the molecular classification of GI tract tumors through biomarkers such as gene alternations, MSI, EBV, and chromosomal instability (CIN). However, the clinical utility of these biomarkers remained limited. Here we reported a comprehensive genomic profiling study, comparing molecular characteristics between unresectable gastric and colon cancer patients. The study also investigated
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19

Zhang, Meirong, Mingzhu Li, Yue Zhang, et al. "Abstract 742: Development and evaluation of a non-invasive qPCR assay for sensitive detection of FGFR2/3 alterations in urine samples as a companion diagnostic for erdafitinib." Cancer Research 85, no. 8_Supplement_1 (2025): 742. https://doi.org/10.1158/1538-7445.am2025-742.

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Abstract Introduction: Fibroblast growth factor receptor (FGFR) alterations, including point mutations and gene fusions, play a pivotal role in various cancers, particularly urothelial carcinoma. Erdafitinib, an FDA-approved therapy for locally advanced or metastatic urothelial carcinoma with FGFR2/3 alterations, currently relies on tissue-based diagnostics, which are invasive and may not always be feasible. Non-invasive liquid biopsy approaches, such as qPCR assays using urine cell pellets (UCP), offer significant advantages in terms of patient convenience and safety while providing accurate
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Xie, Lu, Zhenyu Cai, Xiaodong Tang, et al. "Abstract 5669: Distinct genetic features between osteosarcomas firstly metastasizing to bone and to lung." Cancer Research 82, no. 12_Supplement (2022): 5669. http://dx.doi.org/10.1158/1538-7445.am2022-5669.

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Abstract Background Osteosarcoma (OS) is a highly aggressive malignant tumor of mesenchymal origin and prone to early hematogenous metastases. The 5-year overall survival of metastatic OS is only approximately 20% to 30%. Therefore, it is still clinical dilemma in the treatment of OS. Thus,understanding the molecular features of metastatic osteosarcoma become increasingly important. Methods Formalin-fixed, paraffin-embedded or fresh tissues and matched blood samples were collected from OS patients for whole exome sequencing using next-generation sequencing at OrigiMed (Shanghai, China), a Coll
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Shimizu, Masahiro, Daisuke Nishida, Ayaka Kikuchi, and Susumu Arai. "Rutile TiO2 As a Negative Electrode Material for Proton Rechargeable Batteries." ECS Meeting Abstracts MA2024-02, no. 6 (2024): 759. https://doi.org/10.1149/ma2024-026759mtgabs.

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With the increasing importance of rechargeable batteries, the use of monovalent alkali metal ions such as Na and K ions has been actively investigated. However, there have been relatively few research reports on proton rechargeable batteries. When using protons as a carrier ion, there are concerns about irreversible H2 evolution due to the poor electrochemical stability of aqueous electrolytes. If the fast proton conduction originating from Grötthuss mechanism can be utilized, the rechargeable batteries with water-based electrolytes including protons as carrier ions that combine safety and rap
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Ouyang, Jie, Yifen Wu, Pengfei Qian, et al. "Abstract P2-12-22: A multicenter, single-arm, phase II clinical trial of oral CDK4/6 inhibitor darciclib in combination with endocrine therapy in adjuvant treatment for hormone receptor-positive, HER2-negative female breast cancer." Clinical Cancer Research 31, no. 12_Supplement (2025): P2–12–22—P2–12–22. https://doi.org/10.1158/1557-3265.sabcs24-p2-12-22.

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Abstract Background: Although the role of endocrine therapy in the adjuvant treatment of HR+/HER2- breast cancer has been established, Early HR positive and HER2 negative breast cancer show a long-term risk of recurrence. Studies have shown that about 20% of patients experience recurrence and metastasis after receiving adjuvant endocrine therapy for 5 years. CDK4/6 inhibitor combined with endocrine therapy for HR+/HER2- breast cancer has been proven to have synergistic effects. Previous studies have shown that Abemaciclib and ribociclib can reduce the risk of recurrence and increase iDFS in ea
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Suzy, Fawzi. "Glycosylated hemoglobin (HBA1c) levels as follow-up for clinical outcome (cardiac events) after coronary artery stenting in diabetic patients." Biolife 5, no. 4 (2022): 557–63. https://doi.org/10.5281/zenodo.7393268.

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<strong>ABSTRACT</strong> Diabetes mellitus (DM) has&nbsp; been recognized to be&nbsp; a strong risk factor&nbsp; for cardiovascular disease (CVD) and has been proved to be an independent risk factor for in-stent restenosis. After stent implantation, restenosis remains the &ldquo;Achilles&rsquo; heel&rdquo; of percutaneous coronary intervention (PCI) and diabetic patients compared to non-diabetics still have poorer clinical outcomes. Objective:(Aim of Work)&nbsp; is to evaluate whether the level of&nbsp; HbA1c - as an&nbsp; indicator&nbsp; for&nbsp;&nbsp; the glycaemic control in diabetic pati
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Zhang, Xu Hannah, Vu N. Ngo, Natalie Sandoval та ін. "Role of p38γ - NFATc4 - IL17A Pathway As a Potential Therapeutic Target in Cutaneous T Cell Lymphoma". Blood 128, № 22 (2016): 2725. http://dx.doi.org/10.1182/blood.v128.22.2725.2725.

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Abstract Cutaneous T cell lymphoma (CTCL) is an incurable skin homing T cell malignancy. We have previously reported p38 as therapeutic targets for CTCL.1 However, the mechanism underlying p38 signaling is not completely understood. To further investigate p38 and its downstream signaling components, we examined public database of gene expression and found that p38γ is overexpressed in CTCL as compared to normal T cells. In addition, p38γ has negligible expression in normal lymphoid tissues, with the exception of high level expressed in smooth and cardiac muscle cells. We have demonstrated that
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Huang, Y. Q., Q. B. Zhang, J. X. Zheng, et al. "POS0136 ROLES OF AUTOPHAGY IN THE PATHOGENESIS OF PRIMARY GOUTY ARTHRITIS." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 280.1–280. http://dx.doi.org/10.1136/annrheumdis-2021-eular.3592.

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Background:Gout is a chronic autoinflammatory disease caused by monosodium urate (MSU) crystal deposition [1].Acute gout is characterized by an acute inflammatory reaction that resolves spontaneously within a few days[2], which is one of the distinguishing features of gout compared to other arthropathies or self-inflammatory diseases. Autophagy is a lysosomal degradation pathway that is essential for cellular growth, survival, differentiation, development and homeostasis [3]. Studies have demonstrated that autophagy might play a key role in the pathogenesis of primary gouty arthritis (GA) [4-7
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Lo, Tung Yan, Anthony Siu Lung Chan, Suet Ting Cheung, Lisa Ying Yung, Manton Man Hon Leung, and Yung Hou Wong. "Multi-target regulatory mechanism of Yang Xin Tang − a traditional Chinese medicine against dementia." Chinese Medicine 18, no. 1 (2023). http://dx.doi.org/10.1186/s13020-023-00813-w.

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Abstract Background Yang Xin Tang (YXT) is a traditional Chinese herbal preparation which has been reported to improve cognitive function and memory in patients with dementia. As the underlying mechanism of action of YXT has not been elucidated, we examined the effects of YXT and its major herbal components in regulating gene transcription and molecular targets related to Alzheimer’s disease (AD). Methods Aqueous and ethanol extracts of YXT and selected herbal components were prepared and validated by standard methods. A series of biochemical and cellular assays were employed to assess the abi
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Li, Peng, Tong Jin, Qing-Qiong Deng, et al. "Dissecting Combinational Mechanisms of Herbal Formula from a Transcriptome-based Multi-scale Network Pharmacology Model." World Journal of Traditional Chinese Medicine, March 22, 2024. http://dx.doi.org/10.4103/wjtcm.wjtcm_54_23.

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Abstract Objective: Illumination of the integrative effects of herbs in a formula is a bottleneck that limits the development of traditional Chinese medicine (TCM). In the present study, we developed a transcriptome-based multi-scale network pharmacology model to explore the combined effects of different herbs. Materials and Methods: First, we curated gene signatures at different biological scales, from the molecular to higher tissue levels, including tissues, cells, pathological processes, biological processes, pathways, and targets. Second, using the Xiexin Tang (XXT) formula as an example,
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Teles, Samuel Gomes da Silva, Maria Cecília Simões Riscado de Castro, Sabrina Nogueira Dutra, and Lídia Márcia Silva Santos. "Uso da saliva como um espécime alternativo para diagnóstico de COVID-19: uma revisão sistemática." ARCHIVES OF HEALTH INVESTIGATION 9, no. 4 (2020). http://dx.doi.org/10.21270/archi.v9i4.5114.

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Introdução: O padrão ouro atual para detectar o RNA de SARS-CoV-2 é por reação em cadeia da polimerase em tempo real de transcrição reversa (RT-rtPCR) em swabs nasofaríngeos (NPS). Por esse motivo, a demanda pelos NPS aumentou e sua escassez se tornou uma realidade em muitos países. Com isso o uso da saliva se mostra uma alternativa promissora na triagem epidemiológica além de ser de fácil coleta e não invasiva. Objetivo: realizar uma revisão sistemática da literatura para avaliar o uso da saliva como um espécime alternativo para a detecção de SARS-CoV-2. Metodologia: A pesquisa sistemática fo
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Liang, Zhibin, Huidi Liu, Zeling Xu, and Lian-hui Zhang. "First Report of Pectobacterium aroidearum Causing Soft Rot in Olecranon Honey Peach (Prunus persica L.) in China." Plant Disease, November 29, 2021. http://dx.doi.org/10.1094/pdis-10-21-2238-pdn.

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Olecranon honey peach (Prunus persica L.) is a popular fruit tree cultivated in Guangdong Province of China. Due to its excellent economic values and popularity, it has recently been widely adopted and planted in several other southern Provinces and Autonomous Region in China, including Yunnan, Hunan, Jiangxi, Guizhou, and Guangxi. In Lianping County of Guangdong Province alone, the annual peach fruit production was about 78,800 tonnes (Xie et al. 2017). In July 2021, peach fruits showing soft rot symptoms were collected from an olecranon honey peach plantation in Lechang, Guangdong, China. Sy
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Zhang, Tianning, Huanhuan Liu, Qingni Song, et al. "First Report of Leaf Spot Caused by Corynespora cassiicola on Viburnum odoratissimum Ker-Gawl. var. awabuki (K. Koch) Zabel ex Rumpl. (sweet viburnum) in China." Plant Disease, September 21, 2021. http://dx.doi.org/10.1094/pdis-04-21-0849-pdn.

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Sweet viburnum [Viburnum odoratissimum Ker-Gawl. var. awabuki (K. Koch) Zabel ex Rumpl.] belonging to the family Adoxaceae, is a medical and landscape plant, native to Korea (Jeju Island), Taiwan, and Japan (Edita 1988). In June and September 2019, leaf spots were observed on approximately 65% to 80% of sweet viburnum plants in a hedgerow located in Fenghe Xincheng District (28°41'52.9"N 115°52'14.3"E) in Nanchang, China. Initial symptoms of disease appeared as dark brown spots surrounded by red halos (Figure 1 A), which expanded irregularly. Finally, the center of the lesions desiccated and b
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Quynh, Nguyen Thuy, Le Thi Thanh Nhan, Le Lan Phuong, et al. "Mitochondrial A10398G Alteration in Plasma Exosome of Non-small Cell Lung Cancer Patients." VNU Journal of Science: Medical and Pharmaceutical Sciences 36, no. 4 (2020). http://dx.doi.org/10.25073/2588-1132/vnumps.4275.

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This study identifies A10398G alteration of mitochondrial ND3 gene in plasma exosome of 29 non-small cell lung cancer (NSCLC) patients, 31 controls and 13 pairs of tumor tissue and adjacent tissue of NSCLC patients, thereby assessing the relationship between this alteration in plasma exosome and tissue as well as the pathological characteristics of NSCLC patients. Using the PCR-RFLP method, the homoplasmy and heteroplasmy of A10398G were initially identified in mitochondrial DNA from both exosomes and lung tissues. The rate of variant 10398G in plasma exosome was 62.1% in the NSCLC group and 6
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"Acknowledgment of Abstract Graders." Circulation 124, suppl_21 (2011). https://doi.org/10.1161/circ.124.suppl_21.a401.

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We would like to thank the following abstract graders for their invaluable time and effort in reviewing abstracts for Scientific Sessions 2011. Brian Abbott Friederike K. Keating Geoffrey Abbott John Kern Evan Abel Karl Kern Benjamin S. Abella Morton Kern Theodore Abraham Amit Khera William T. Abraham Raymond J. Kim Stephan Achenbach Sue Kimm Michael A. Acker Carey D. Kimmelstiel Michael J. Ackerman Jacobo Kirsch David H. Adams Joel Kirsh M. Jacob Adams Lorrie Kirshenbaum Ted Adams Raj Kishore Philip A. Ades Masafumi Kitakaze Gail K. Adler Andre Kleber Sunil K. Agarwal Neil S. Kleiman Frank Ag
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"Acknowledgment of Abstract Reviewers." Circulation 128, suppl_22 (2013). https://doi.org/10.1161/circ.128.suppl_22.a401.

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Abbara, Suhny Abbott, J Dawn Abe, Jun-ichi Abraham, William T. Achenbach, Stephan Ackerman, Michael J. Adabag, Selcuk Adams, Ted Adatya, Sirtaz Ades, Philip A. Ahmed, Bina Aikawa, Elena Ailawadi, Gorav Aizawa, Yoshifusa Aizer, Anthony Akagi, Teiji Akar, Fadi Akhter, Shahab Al Khatib, Sana Al-Ahmad, Amin Al-Mallah, Mouaz Alberts, Mark J. Alexander, John H.. Alexander, Mark Ali, Mo Allen, Larry A. Allen, Norrina B. Allison, Matthew A. Ambrosio, Giuseppe Amsterdam, Ezra Anand, Inder S. Andelfinger, Gregor Anderson, Mark E. Andresen, Brad Antoniucci, David Anversa, Piero Anyanwu, Ani Aon, Miguel A
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"Acknowledgment of Abstract Graders." Circulation 126, suppl_21 (2012). https://doi.org/10.1161/circ.126.suppl_21.a401.

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Abbara, Suhny Georgiou, Demetrios naka, yoshifumi Abbott, Brian Gerszten, Robert Nakagawa, Yoshihisa Abbott, Geoffrey . Gewillig, Marc Nakamura, Kazufumi Abe, Jun-ichi Ghali, Jalal K. Nakamura, Yasuyuki Abella, Benjamin S. Ghanayem, Nancy Nakanishi, Toshio Abraham, Theodore Ghanayem, Nancy Nakatani, Toshio Abraham, William T. Ghosh, Shobha Narayan, Sanjiv M. Achenbach, Stephan Giachelli, Cecilia M. Natale, Andrea Acker, Michael A. Gidding, Samuel S. Natarajan, Rama Ackerman, Michael J. Gidding, Samuel S. Nattel, Stanley Adams, M. Jacob Gilchrist, Ian Nazarian, Saman Adams, Ted Giles, Thomas D.
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Thanh Binh, Nguyen Thi, Nguyen Thi Hai Yen, Dang Kim Thu, Nguyen Thanh Hai, and Bui Thanh Tung. "The Potential of Medicinal Plants and Bioactive Compounds in the Fight Against COVID-19." VNU Journal of Science: Medical and Pharmaceutical Sciences 37, no. 3 (2021). http://dx.doi.org/10.25073/2588-1132/vnumps.4372.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus , is causing a serious worldwide COVID-19 pandemic. The emergence of strains with rapid spread and unpredictable changes is the cause of the increase in morbidity and mortality rates. A number of drugs as well as vaccines are currently being used to relieve symptoms, prevent and treat the disease caused by this virus. However, the number of approved drugs is still very limited due to their effectiveness and side effects. In such a situation, medicinal plants and bioactive compounds are considered a highly valuabl
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Dolomatov, S.I., та W. Zukow. "Эпигенетика почек = Kidneys epigenetics". 7 липня 2019. https://doi.org/10.5281/zenodo.3270754.

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<strong>Dolomatov S.I., Zukow W. </strong><strong>Эпигенетика почек</strong><strong> = Kidney</strong><strong>s</strong><strong> epigenetics</strong><strong>. </strong><strong>RSW. Radom,</strong><strong> 144 </strong><strong>p. ISBN </strong><strong>9780359774524</strong><strong>.</strong><strong> DOI </strong><strong>http://dx.doi.org/10.5281/zenodo.3270699</strong><strong> PBN Poland </strong><strong>https://pbn.nauka.gov.pl/sedno-webapp/works/917606</strong> &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; <strong>Radomska Szkoła Wyższa w Radomiu, Radom, Poland</strong> &nbsp; &nbsp; &nbsp; &nbsp; &nbsp
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