Academic literature on the topic 'Xuan gou'

4051 Background: Before 2000, trials comparing BSC +/- chemo for aGOAC showed overall survival (OS) benefit, but in predominantly fit patients (pts). We have revisited this question in a modern context, using low-dose chemo in a frail population, with comprehensive baseline health and frailty assessment. Methods: In the GO2 trial, elderly and/or frail aGOAC pts with a “certain” indication for chemo were randomised between 3 chemo doses. In this GO2 substudy, pts with an “uncertain” indication for chemo were instead randomised to BSC ± the lowest dose chemo. Pts were eligible if clinician and pt agreed the indication for chemo was uncertain. There was no PS threshold, but eGFR ≥30 and bili < 2xULN were required. Baseline assessment included global QL, symptom & functional scales, frailty and comorbidity. Randomisation was 1:1 to BSC alone, or with oxaliplatin 78 mg/m2 d1, capecitabine 375 mg/m2 bd d1-21 (modified if eGFR 30-50 ml/min or bili 1.5-2.0 xULN), q21d. QL was reassessed after 9 and 18 wks. The primary endpoint analysis was OS, adjusted for baseline factors. The sample size for this exploratory sub-study was not pre-set, but around 60 pts were anticipated. Results: 558 pts entered GO2 at 61 centres 2014-17, of whom only 45 pts (8%) at 21 centres entered this uncertain randomisation. This would provide 80% power at p = 0.05 (2-tailed) to detect an OS HR of 0.3. OS was shorter in pts with worse baseline PS (p<0.01) or distant mets (p<0.05). OS was not significantly improved with chemo; however we cannot exclude HR >0.32. QL deteriorated less with BSC+chemo than with BSC alone. Conclusions: In this frail, poor PS population, we observed a small survival benefit with chemo but this did not reach statistical significance. Clinicians should carefully consider BSC alone as a valid treatment option for aGOAC pts with poor PS and/or frailty. Clinical trial information: 44687907. [Table: see text]

4006 Background: Many pts with aGOAC are elderly and/or frail. We previously compared epirubin/ oxaliplatin/ capecitabine (EOCap) vs OCap vs Cap in a pick-the-winner study and found OCap best. GO2 was designed to find the optimum dose of OCap and to explore the use of an objective baseline geriatric assessment to individualize doses for maximum Overall Treatment Utility (OTU), a composite of clinical benefit, tolerability, QL and patient value. Methods: Pts with aGOAC were eligible if unsuitable for full-dose EOCap due to age or frailty, but fit for OCap; GFR ≥ 30, bili <2x ULN. Baseline assessment included global QL; symptoms; functional scales; comorbidity; frailty. Randomization was 1:1:1 to dose Level A (Ox 130 mg/m2d1, Cap 625 mg/m2bd d1-21, q21d), B (80% Level A doses) or C (60% Level A doses). Pts with GFR 30-50 ml/min or bili 1.5-2.0 xULN received 75% of the allocated dose of Cap. At 9 wks, pts were scored for OTU. Continuation thereafter was based on clinical judgement. Non-inferiority (vs A) was assessed using PFS censored at 12 months, with boundary HR 1.34 (based on discussion with pts and clinicians), needing 284 PFS events per 2-way comparison. Baseline fitness was assessed as predictive of OTU, overall and by interaction with dose level. Results: 514 pts were randomised, 2014-17, at 61 UK centres. Clinical trial information: 44687907. Non-inferiority of PFS is confirmed for Level B vs A (HR 1.09, CI 0.89-1.32) and for Level C vs A (HR 1.10, CI 0.90-1.33). Level C pts had less toxicity and better OTU outcomes than A or B. When analysed by baseline age, frailty and PS, Level C produced the best OTU even in younger, less frail and better PS patients; no group was identified who benefit more from the higher dose levels. Conclusions: This is the largest RCT to date specifically investigating frail and/or elderly aGOAC pts, and should guide future treatment. The lowest dose tested was non-inferior in terms of PFS and produced less toxicity and better overall treatment utility.[Table: see text]

Cardiovascular disease is the leading cause of death in the world. Cardiovascular risk assessment is an important step in preventing and treating the disease. The current study assesses the 10-year risk of cardiovascular disease in 306 VNU’s office workers in 2016-2017 based on the 2008 Framingham Risk Score. The study results show that the average risk score was 4.05 ± 4.76%; low risk was 90.52%; moderate risk: 7.85 %; and high to very high risk was 1.63%. Men have a higher risk score than women (p <0.001). The ten-year cardiovascular risk score shows that age and systolic blood pressure correlated with the risk at a medium level, and cholesterol and HDL correlated with it at a low level. Keywords Framingham Risk Score 2008, 10-year cardiovascular risk score, hypertension, blood cholesterol, blood HDL. References [1] Cardiovasculardiseases, http://www.who.int/en/newsroom/factsheets/detail/cardiovascular diseases-(cvds), (truy cập ngày 22/03/2019).[2] A.R. Gregory et al, Global, regional, and national burden of cardiovascular diseases for 10 Causes, 1990 to 2015, Journal of the American college of cardiology. 70(1) (2017) 1–25.[3] E. Gresham, T.E. Fitzpatrick, P.A. Wolf et al, Residual disability in survivors of stroke--the Framingham study, N Engl J Med. 293(19) (1975) 954–956.[4] T.A. Pearson, S.N. Blair, S.R. Danielset et al, AHA guidelines for primary prevention of cardiovascular disease and stroke: 2002 update: consensus panel guide to comprehensive risk reduction for adult patients without coronary or other atherosclerotic vascular diseases, American heart association science advisory and coordinating committee, Circulation. 106(3) (2002) 388–391.[5] I. Graham, D. Atar, K. B. Johnsen et al, European guidelines on cardiovascular disease prevention in clinical practice: full text - Fourth joint task force of the European society of cardiology and other societies on cardiovascular disease prevention in clinical practice constituted by representatives of nine societies and by invited experts, Euro heart J. 28(19) (2007) 2375-2414.[6] S.S. Mahmood, D. Levy, R.S. Vasanet et al, The Framingham heart study and the epidemiology of cardiovascular diseases: a historical perspective, Lancet. 383(9921) (2014) 999–1008.[7] J.A.A.G. Damen, L. Hooft, E. Schuit et al, Prediction models for cardiovascular disease risk in the general population: systematic review, BMJ. 353(2016) 1-10.[8] L.Q.H. Goh, T.A. Welborn, S.S. Dhaliwal, Independent external validation of cardiovascular disease mortality in women utilising Framingham and SCORE risk models: a mortality follow-up study, BMC women health. 14 (2014) 118-129.[9] L.M. A. Rodenas, J.A. C. Herencia, J.A. D. Garrote et al, Framingham risk score for prediction of cardiovascular diseases: a population-based study from southern Europe, PLoS One. 8(9) (2013) 1-10.[10] G.M. Park, Y.H. Kim, Model for predicting cardiovascular disease: insights from a Korean cardiovascular risk model, Pulse (Basel). 3(2) (2015) 153–157.[11] Trần Kim Trang, Nguy cơ 10 năm của bệnh tim mạch ở nữ giới tăng huyết áp, Y học thành phố Hồ Chí Minh. 16(1) (2012) 181-185.[12] Trương Thanh Sơn, Nguyễn Văn Trí, Trương Quang Bình, Nghiên cứu áp dụng thang điểm Framingham nhằm định nguy cơ bệnh động mạch vành trong 10 năm tới tại bệnh viện đa khóa Bình Dương, Y học thành phố Hồ Chí Minh. 15(1) (2011) 207-212. [13] Nguyễn Thị Kim Thủy, Dự báo nguy cơ mắc bệnh động mạch vành trong 10 năm theo thang điểm Frammingham ở bệnh nhân tăng huyết áp nguyên phát, Y học thực hành. 802(1) (2012) 27-29. [14] Nguyễn Hồng Huệ, Nguyễn Đức Công, Nghiên cứu ước tính nguy cơ bệnh động mạch vành trong 10 năm tới theo thang điểm Framingham qua 500 trường hợp, Y học thành phố Hồ Chí Minh. 15(2) (2011) 38-44. [15] C.V. Aram et al, The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure, National heart, lung and blood institute - National institutes of health, NIH publication no. 04-5230, US, (2014), pp 13.[16] National Heart, Lung and Blood Institute, Third Report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult treatment panel III) Final report, National institutes of health, part II, US, (2002), pp 5-10. [17] World Health Organization, The Asia-Pacific perspective: redefining obesity and its treatment, Geneva: World health organization western pacific regional office, (2000), 18-19.[18] N.Q. Nguyen, S.T. Pham, L.D. Do et al, Cardiovascular disease risk factor patterns and their implications for intervention strategies in Vietnam, Int J Hypertens, ID. 560397, (2012), 1-11.[19] M. Nakhaie, B. Koor, S. Salehiet al, Prediction of cardiovascular disease risk using framingham risk score among office workers, Iran, 2017, Saudi journal of kidney diseases and transplantation. 29(3) (2018) 608-614. [20] Trịnh Xuân Thắng, Nghiên cứu các yếu tố nguy cơ bệnh tim mạch ở người >25 tuổi tại 2 quận huyện Hà Nội, Luận văn thạc sỹ, Đại học Y Hà Nội, (2013). [21] Nguyễn Hoàng Liên, Văn Thế Trung, Xác định nguy cơ tim mạch theo thang điểm Framingham trên bệnh nhân vẩy nến tại bệnh viện da liễu TP. Hồ Chí Minh, Y Học TP. Hồ Chí Minh, 18(1), (2014), 79-85. [22] R. Gupta, V. Kaul, A. Agrawalet et al, Cardiovascular risk according to educational status in India, Preventive medicine. 51(5) (2010) 408–411.[23] C.A. Jones, L. Ross, N. Suraniet al, Framingham ten-year general cardiovascular disease risk: agreement between BMI-based and cholesterol-based estimates in a South Asian convenience sample, PLOS ONE. 10(3) (2015) e0119183.[24] K.S. Tyrrell, H.C. Lassila, E. Meilahn et al, Carotid atherosclerosis in premenopausal and postmenopausal women and its association with risk factors measured after menopause, Stroke. 29(6) (1998) 1116–1121.[25] Margaret Kelly Hayes et al, Influence of age and health behaviors on stroke risk: lessons from longitudinal studies, J Am Geriatr Soc. 58(2) (2010) 325–328.[26] D. Sugiyama, T. Okamura, M. Watanabe et al, Risk of hypercholesterolemia for cardiovascular disease and the population attributable fraction in a 24-year Japanese cohort study, J Atheroscler Thromb. 22(1) (2015) 95–107.[27] M.R. Law, N.J. Wald, S.G. Thompson, By how much and how quickly does reduction in serum cholesterol concentration lower risk of ischaemic heart disease, BMJ. 308(6925) (1994) 367–372.[28] Abolfazl Mohammadbeigi et al, Dyslipidemia prevalence in Iranian adult men: the impact of population-based screening on the detection of undiagnosed patients, World J men health. 33(3) (2015) 167-173. [29] R.S. Joshi et al, Prevalence of dyslipidemia in urban and rural India: The ICMR–INDIAB Study, PloS ONE. 9(5) (2014) 1-9.[30] Wichai Aekplakorn et al, Prevalence of dyslipidemia and management in the Thai population: national health examination survey IV, 2009, Journal of lipids. (2014) 1-13.[31] Asia Pacific, Cohort Studies Collaboration, cholesterol, diabetes and major cardiovascular diseases in the Asia-pacific region, Diabetologia. 50(11) (2003) 2289-2297.[32] S. Lewington, R. Clarke, N. Qizilbash, R. Peto, R. Collins et al, Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies, Lancet. 360(9349) (2002) 1903–1913.[33] Viet Nam national STEPS Survey 2015, https://www.who.int/ncds/un-task-force/steps-survey-vietnam2015.pdf, (2015), (truy cập ngày 09/03/2019).[34] Nguyễn Lân Việt, Kết quả mới nhất điều tra tăng huyết áp toàn quốc năm 2015 – 2016, Hội tim mạch Việt Nam, http://www.yhth.vn/hoinghitanghuyetapvietnamlanthuii_d3378.aspx, (2016) (truy cập ngày 11/02/2019).[35] M. Satoh, et al, Combined effect of blood pressure and total cholesterol levels on long-term risks of subtypes of cardiovascular death: evidence for cardiovascular prevention from observational cohorts in Japan, hypertension. 65(3) (2015) 517–524.

The vernacular fiction 'novel' is a genre typically associated with the explosion of commercial printing activity that occurred in the late sixteenth century. However, by that time, representative works such as the Shuihu zhuan and Sanguo yanyi had already been in print for several decades. Moreover, those early print editions were printed not by commercial entities but rather the elite of the Jiajing court. In order to better understand the genre as a print phenomenon, this paper explores the publishing output of one of those elites: Guo Xun (1475- 1542), Marquis of Wuding. In addition to vernacular fiction, Guo printed a number of other types of books as well. This paper examines the entirety of his publishing activities in order to better contextualize the vernacular novel at this early stage in its life in print.

碩士
國立屏東教育大學
視覺藝術教育學系
97
For breaking the shackles of religious art form, explore the new religious art show, the discussion of the text from the Taoist yin and yang of the five elements management solution, I Taoist deities large number of substances, it will be the main draw to leave a specific God Tien God, As its characteristics, in order to translate into personal creative content, the ultimate goal of the study to explore the yin and yang, five elements in the level of the art show. From Taoist yin and yang of the five elements of the inquiry will be transferred to the religious and cultural connotation of the visual arts on the integration of applications. Through the Taoist ceremony of the sources of development, the development of Taoism in Taiwan and now understand the signs, yin and yang, five elements of identification tests, I found that the traditional social customs, religious customs Lai, ethnic and cultural characteristics, and so on ..., from the color science and the arts Sociology degree angle, into the basic content creation, its color and space as the main structure and management of religious-chul, the integration of modern art and design performance in order to view concept art, installation art shows as a way to complex space device Artistic expression. Creative concept of integrated management of traditional and contemporary forms of artistic expression as a whole show. Look forward to watching in reference to this text theory works, "Emotions, Colors, Xuan-tian" The shows, from the arts degree angle to see these religious culture, which enjoy the behind-oldest faith and say, the degree angle from a new look at religious art, to accept their own culture''s beauty, which belong to us Local cultural characteristics, but also to be local artists in depth perception, more innovative in order to be able to continue to work to show the way.

碩士
國立屏東教育大學
視覺藝術學系
97
This study mainly discusses the original meaning of Xuan-Tian God that has strong religious impact on the Chinese Society and tries to comprehend ,from modern people’s astronomical viewpoint, the cultural influence and application derived from our ancestors’ astrological observation and creation. Therefore, this study is mainly researched into those astrological symbols that are related to Xuan-Tian God. The researcher’s series of Polaris-based creations are done through understanding the ideology of Taorism’s theory of “man is an integral part of nature” from ancient China’s cosmological perspective and further discuss the intrinsic nature of Xuan-Tian God from a contemporary viewpoint. The influential role modal of Xuan-Tian God existed among ancient followers along with its crucial impact on modern religion and culture have been transformed into elements for personal art creation which has been interpreted through an artistic approach. Viewers are then guided for personal experiments which turn the religious and cultural cognition of Xuan-Tian God into abstract and conceptual ones. Thus, the intrinsic nature of Xuan-Tian God has been re-contemplated so as to present both the researcher’s creation concept and the new look of the religious art.

碩士
國立屏東教育大學
視覺藝術學系
97
《Abstract》 The Xuan-Tian God is the most important god in the Taoism, and holds the great position in Taoism.The faith of Xuan-Tian God tells the ultimate concern and care to human life; it’s the classical spirit of Taoism. This essay discusses the history of Xuan-Tian God and its position in Taoism. In addition, I will focus on the content of Xuan-Tian God’s faith regarding the connection of life to death, as the discourse and theory of my essay. The Xuan-Tian God concerns the original admiral of galaxy, animals, and the human god. The underlying meanings are so deep and present the reconciliation of God, land and human. The images of Xuan-Tian God, fulfilled with the God of procreate and hell, cover the life and death. Therefore, this research uses the artwork to discuss the relationship of Xuan-Tian God to the nature of life, and integrate the religious concept of the west and the east to present the immortal and to explain the eternal soul and the nature of life. I expect these applications of creative concept and presentation to highlight the diverse directions of art field.

碩士
國立臺南大學
台灣文化研究所碩士班
101
As a belief of orientation god, Xuan Tian God is Located in the North with supreme status and vivid images. The belief originates from the worship of nature, such as star god, animal god and water god. With the passage of time, it transforms into a personal god and transcends the four spiritual creatures. As a result of warfare, the Han people migrated along with the belief of Xuan Tian God from the North to the South, then to Taiwan and finally settled down in Tainan. The gist of this research is to explore the belief of Xuan Tian God in Tainan over a time span from the period of Koxinga to the days before the merger of Tainan city and county. It introduces the current locations and histories of the total 14 temples, which mainly worship Xian Tian God and spread over the Districts of the East, the South, the Middle-west and the North of Tainan, so as to understand the development of the belief of Xuan Tian God in individual District in Tainan. It also investigates the cultural characters of the belief of Xuan Tian God in Tainan, such as the legends and the functions, introduces the associated deities, and outlines the subordinates of Xuan Tian God. It hopes that the people in the future can realize the belief of Xuan Tian God and the background and implications of how the belief migrated to and settled down in Tainan. Therefore this research studies the belief of Xuan Tian God in Tainan. Following the preliminary understanding of the evolution from Xuan Wu to Xuan Tian God, it explores the developmental context of this belief from the time it first migrated to Tainan till the days before the merger of Tainan city and county.

碩士
國立屏東師範學院
視覺藝術教育學系碩士班
94
Taoism’s Ceremony：From Visual Art’s prespective --Take the religious ceremony of Xuan-tian God for example-- Abstract In order to break through the constraint of the traditional religion art form, and to explore new looks of religion art, I learn from Taoism’s ceremony and activities that there are numerous Taoism's gods. I choose one particular god, the Xuan-tian God, as an example and analyze his features, and further incorporate such into my work. The purpose of this research is to discuss the artistic aspect of Taoism's ceremony. I use various angles of iconography, semiology, traditional art type of facial make ups, chromatology and social art as the fundamental spirit of my work. It uses the totem and shape in the shape of ancient Chinese word-sign and pattern as its main framework, which is in combination with religion art, and merging with contemporary art form. By means of conceptual art and installation art, I expect to show a general figure art. I represent my whole ideas in the form of mixture of traditional and contemporary art. I hope people may view these religious ceremonies from an artistic viewpoint, and appreciate the old beliefs and legend contained therein. From a new angle to see the religious art, people may see the beauty of our own culture. These local culture features will continuously be shown and cultivated in a more innovative way after more local artists deeply learn and recognize them.

碩士
國立高雄應用科技大學
文化創意產業系
104
Guogou village is a tranquil village with genuine and warm-hearted residents, and a sincere and respectful culture which has a long history. A cleansing ceremony is held to explore the relationship between the religion and the residents who worship there. We will discuss the Jiande Temple, the main temple of Chiayi’s Guogou township, where the supreme deity is Prince Li. There is a folk tale of Jiande Temple known as the “Huo Deng Ye Xun”, which involves a ceremony of intangible assets. We first introduce the culture and lifestyle of the residents of Putai, Chiayi, as well as their environment and industry in order to further understand the history and social fabric of the Jiande Temple, and then thoroughly analyse the effects of the Fire Lamp Night Patrol ceremony on the values of the local society, and the significance of the event. Furthermore, we analyse how purely regional beliefs develop into intangible cultural assets and combine with the cultural policies of the temple, and stimulate community integration and development. Also, this article will through the discussion of the Firelight Nightwatch event and temple ceremony, also help to further increase the understanding and awareness of Chiayi’s Jiande Temple Fire Lamp Night Patrol festival.

This chapter details Xuan's path that led her from the jungle to London and back to Saigon in 1956. It narrates how she first met Lau in the maquis and then in England where they got married. It also talks about Xuan's studies in piano at the Royal College of Music and Lau's education at the London School of Economics and Oxford. The chapter discusses Xuan and Lau's return to southern Vietnam, where they had to keep a low profile teaching piano and raising four children. It mentions Xuan's resentment of the rule of Ngo Dinh Diem, which she described as a dictatorial regime whose injustice the people had to bear daily.