Academic literature on the topic 'Xun Xian Di 1 gao ji zhong xue'

Author: Grafiati

Published: 26 July 2024

Last updated: 31 July 2025

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Journal articles on the topic "Xun Xian Di 1 gao ji zhong xue"

Cheng, Ying, Xiqin Zhang, Lin Wu, et al. "Abstract CT126: Aumolertinib as adjuvant therapy in patients with stage II-IIIB EGFR-mutated NSCLC after complete tumor resection: A randomized, double-blind, placebo-controlled, phase 3 trial (ARTS)." Cancer Research 85, no. 8_Supplement_2 (2025): CT126. https://doi.org/10.1158/1538-7445.am2025-ct126.

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Abstract Background: Lung cancer is the primary cause of cancer-related morbidity and mortality globally. Approximately 30% of patients with EGFR mutation (EGFRm) in NSCLC are diagnosed at an early stage and are candidates for curative-intent surgical resection; however, disease recurrence remains a substantial clinical challenge. Aumolertinib is a third-generation EGFR TKI that potently inhibits both sensitizing EGFR mutations (ex19del/L858R) and the resistance mutation T790M. ARTS (NCT04687241) is a randomized, double-blind, placebo-controlled, multicenter, phase 3 trial designed to evaluate