Academic literature on the topic 'Xylometazoline hydrochloride'

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Journal articles on the topic "Xylometazoline hydrochloride"

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Solominchuk, Tetiana, Vitalii Rudiuk, Nataliia Smielova, Alina Deyneka, Tetiana Nesteruk, and Victoriya Georgiyants. "Xylometazoline base suitable for use in lipophilic drug products: development of production technology and analytical methods for quality control." ScienceRise: Pharmaceutical Science, no. 4 (50) (August 30, 2024): 14–22. http://dx.doi.org/10.15587/2519-4852.2024.310656.

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The aim: development of the technology for obtaining the base of xylometazoline, suitable for the development of formulations in combination with essential oils. Development and validation of methods of control of related substances and assay of the obtained base of xylometazoline. Study of the stability of the obtained xylometazoline base under long-term and accelerated conditions. Materials and methods: experimental samples of xylometazoline base were obtained from commercially available xylometazoline hydrochloride and aqueous sodium hydroxide solution. The quality control of the obtained s
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Humphreys, M. R., D. Grant, S. A. McKean, C. Y. Eng, J. Townend, and A. S. Evans. "Xylometazoline hydrochloride 0.1 per cent versus physiological saline in nasal surgical aftercare: a randomised, single-blinded, comparative clinical trial." Journal of Laryngology & Otology 123, no. 1 (2008): 85–90. http://dx.doi.org/10.1017/s002221510800217x.

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AbstractObjectives:A variety of topical preparations are used for symptomatic relief following nasal surgery. The aim of this study was to compare the effect of two commonly used products on patient symptom scores following nasal surgery.Design:Randomised, single-blinded, comparative clinical trial.Setting:A single, secondary otorhinolaryngology centre.Participants:One hundred and twenty patients undergoing septoplasty or functional endoscopic sinus surgery as an isolated procedure between November 2003 and January 2006. Patients undergoing additional nasal procedures were excluded, as were th
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Bezshapochny, Sergey B., and Iryna S. Hychak. "Treatment of adenoid inflammation in children." OTORHINOLARYNGOLOGY, No2(4) 2021 (March 24, 2021): 60–65. http://dx.doi.org/10.37219/2528-8253-2021-2-60.

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Topicality: Inflammation of the adenoid tonsil is one of the common causes of ENT diseases in children. Among the causes of adenoiditis (nasopharyngitis) are infectious - viral and bacterial, allergic and gastric acid irritation in laryngopharyngeal reflux. The aim of our research was to study the effectiveness of topical application of a combination of xylometazoline hydrochloride 0.05% and miramistin 0.01% in the treatment of pediatric patients with pharyngeal tonsillitis. Materials and methods: We selected 60 patients aged 5 to 14 years with endoscopically confirmed adenoid vegetations of I
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Ghose, S., та J. K. Dattagupta. "Structure of xylometazoline (otrivin) hydrochloride, an α-adrenergic agonist". Acta Crystallographica Section C Crystal Structure Communications 42, № 11 (1986): 1524–26. http://dx.doi.org/10.1107/s0108270186091618.

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Divya, Jadhav, Shaikh Misbah, Jain Hitesh, Sahu Asit, and B. Meshram D. "Formulation and Evaluation Xylometazoline Hydrochloride Mucoadhesive Nasal in Situ Gel." International Journal of Pharmaceutical and Bio-Medical Science 02, no. 02 (2022): 18–22. https://doi.org/10.5281/zenodo.6090206.

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The objective of research is to develop a mucoadhesive in-situ nasal gel formulation of xylometazoline hydrochloride for the treatment of allergic rhinitis to avoid possible side effects. Mucoadhesive in-situ nasal gel of xylometazoline hydrochloride was formulated by ionic gelation method using xanthan gum as ionsensitive agent and different grades of HPMC as a viscosifying agent. The prepared batches were evaluated for drug content, pH, gelling time, spreadability, gelling strength, mucoadhesive strength and in-vitro drug release. In vitro drug release study was carried by using diffusion ce
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Joshi, K. S., V. W. Q. Ho, M. E. Smith, and J. R. Tysome. "The effect of topical xylometazoline on Eustachian tube function." Journal of Laryngology & Otology 134, no. 1 (2020): 29–33. http://dx.doi.org/10.1017/s0022215120000158.

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AbstractBackgroundTopical nasal decongestants are frequently used as part of the medical management of symptoms related to Eustachian tube dysfunction.ObjectiveThis study aimed to assess the effect of topical xylometazoline hydrochloride sprayed in the anterior part of the nose on Eustachian tube active and passive opening in healthy ears.MethodsActive and passive Eustachian tube function was assessed in healthy subjects before and after intranasal administration of xylometazoline spray, using tympanometry, video otoscopy, sonotubometry, tubo-tympano-aerodynamic-graphy and tubomanometry.Result
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Larisa, Alagić-Džambić, Dacić Minela, Frljak Amila, Osmanović Omerdić Ehlimana, and Džambić Mirsad. "RP-HPLC Method of the Estimation of Xylometazoline hydrochloride in Nasal Spray Solution." Chemistry Research Journal 5, no. 5 (2020): 31–34. https://doi.org/10.5281/zenodo.13144163.

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<strong>Abstract </strong>A simple, specific, precise and accurate reverse phase HPLC method has been developed for the determination of nasal decongestive, Xylometazoline hydrochloride in nasal spray solution. The chromatographic separation was achieved on column C18, 150 mmx4.6 mm, 3.5 &micro;m, using PDA detector. The mobile phase was acetonitrile and phosphate buffer pH 3.0 (60:40 v:v), at flow rate 1.0 mL/min, detected at 220 nm, at 35&ordm;C temperature for column. The retention times was at about 1.5minutes.The method was validated according to the ICH guidelines with respect to specifi
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Racheva, P. V., D. G. Hristov, and K. B. Gavazov. "Extraction-Chromogenic Systems for Gallium(III) Based on Azo Dyes and Xylometazoline Hydrochloride." Russian Journal of General Chemistry 90, no. 7 (2020): 1351–56. http://dx.doi.org/10.1134/s1070363220070245.

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Prajapati, Nilesh, Mayank Dalal, and Hasumati A. Raj. "Stability Indicating Liquid Chromatographic Method for Estimation of Xylometazoline Hydrochloride in Pharmaceutical Dosage Form." International Journal of Pharmaceutical Chemistry and Analysis 3, no. 3 (2016): 124. http://dx.doi.org/10.5958/2394-2797.2016.00019.8.

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Racheva, Petya V., Antoaneta D. Saravanska, Galya K. Toncheva, et al. "A Semi-Micro Extraction Spectrophotometric Determination of Iron Using 4-Nitrocatechol and Xylometazoline Hydrochloride." Molecules 30, no. 4 (2025): 899. https://doi.org/10.3390/molecules30040899.

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A chromogenic solvent extraction system for Fe(III) based on 4-nitrocatechol (4NC) and xylometazoline hydrochloride (XMH) was investigated. The optimum conditions for extraction spectrophotometric determination of iron were found. Under these conditions, the formula of the extracted complex was (XMH+)3[Fe(4NC)3] and the apparent molar absorption coefficient at λmax = 464 nm was 1.9 × 105 dm3 mol−1 cm−1 (4-fold enrichment). To validate the aforementioned formula and gather information about the spin state of the central Fe(III) ion, a combined experimental-theoretical approach was employed. Thi
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Book chapters on the topic "Xylometazoline hydrochloride"

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Golander, Yechiel, and Wayne J. DeWitte. "Xylometazoline Hydrochloride." In Analytical Profiles of Drug Substances. Elsevier, 1985. http://dx.doi.org/10.1016/s0099-5428(08)60579-1.

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