Academic literature on the topic 'Xylopic acid'

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Journal articles on the topic "Xylopic acid"

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Oge, Elizabeth N., Ernest Obese, Robert P. Biney, et al. "A review of pharmacological effects of xylopic acid." International Journal of Basic & Clinical Pharmacology 9, no. 5 (2020): 813. http://dx.doi.org/10.18203/2319-2003.ijbcp20201765.

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Xylopic acid (15β-acetyloxy-kaur-16-en-19-oic acid) is a kaurene diterpene that can be obtained from various Xylopia spp. Xylopic acid has demonstrated several pharmacological activities in vitro and in vivo. The compound has shown promising effect as a potent analgesic, anti-inflammatory and anti-allergic agent. Xylopic acid is a CNS depressant and was able to ameliorate anxiety-like symptoms in mice in addition to its neuroprotective effects. Deleterious effects of xylopic acid on the reproductive system of mice have been well documented but extensive toxicity study detailing effect of the a
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Osafo, Newman, David D. Obiri, Aaron O. Antwi, and Oduro K. Yeboah. "The acute anti-inflammatory action of xylopic acid isolated from Xylopia aethiopica." Journal of Basic and Clinical Physiology and Pharmacology 29, no. 6 (2018): 659–69. http://dx.doi.org/10.1515/jbcpp-2018-0019.

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AbstractBackgroundOur earlier studies had given evidence of the traditional application ofXylopia aethiopicain the management of inflammation. The principal constituent obtained from its bio-fractionation is xylopic acid. It is a crystalline diterpene that belongs to the class of kauranes. This work sets out to investigate the anti-inflammatory potential of the xylopic acid isolated from the dried fruit ofX. aethiopica.MethodsA preliminary anti-inflammatory study, using the protein denaturation model, andin vivoanti-inflammatory assay were employed in the investigation of acute inflammation. T
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Ameyaw, Elvis Ofori, Ernest Obese, Du-Bois Asante, et al. "Effect of xylopic acid on alloxan-induced diabetic neuropathy in rats." International Journal of Basic & Clinical Pharmacology 10, no. 4 (2021): 333. http://dx.doi.org/10.18203/2319-2003.ijbcp20211011.

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Background: Neuropathic pain is a very disturbing condition commonly found in diabetic patients. This study investigated xylopic acid (XA), the major constituent of Xylopia aethiopica in diabetic neuropathy as well as established possible toxicity of the compound on some selected tissues.Methods: Diabetes was induced in six groups of male rats with 120 mg/kg alloxan monohydrate. Diabetes was confirmed as a blood glucose level >15 mmol/dl. Neuropathic pain was confirmed on day three post-diabetes induction and treatment with 10 mg/kg, 30 mg/kg or 100 mg/kg xylopic acid, 10 mg/kg glibenclamid
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Boampong, J. N., E. O. Ameyaw, B. Aboagye, et al. "The Curative and Prophylactic Effects of Xylopic Acid onPlasmodium bergheiInfection in Mice." Journal of Parasitology Research 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/356107.

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Efforts have been intensified to search for more effective antimalarial agents because of the observed failure of some artemisinin-based combination therapy (ACT) treatments of malaria in Ghana. Xylopic acid, a pure compound isolated from the fruits of theXylopia aethiopica,was investigated to establish its attributable prophylactic, curative antimalarial, and antipyretic properties. The antimalarial properties were determined by employing xylopic acid (10–100 mg/kg) in ICR mice infected withPlasmodium berghei. Xylopic acid exerted significant (P<0.05) effects onP. bergheiinfection similar
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Kofie, William, John Peter Fetse, and Reimmel Kwame Adosraku. "Antimicrobial Activities of Novel Xylopic Acid Derivatives." Journal of Advances in Microbiology 14, no. 1 (2019): 1–6. http://dx.doi.org/10.9734/jamb/2019/45824.

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Kofie, William, John Fetse, and Reimmel Adosraku. "Synthesis and Characterization of Novel Xylopic Acid Derivatives." American Chemical Science Journal 16, no. 2 (2016): 1–12. http://dx.doi.org/10.9734/acsj/2016/27962.

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Alolga, Raphael N., Assogba G. Assanhou, and Vitus Onoja. "QUANTIFICATION OF XYLOPIC ACID AND CHROMATOGRAPHIC FINGERPRINT EVALUATIONS OF THE DRIED FRUITS OF XYLOPIA AETHIOPICA FROM FOUR AFRICAN COUNTRIES." African Journal of Traditional, Complementary and Alternative Medicines 15, no. 3 (2018): 18. http://dx.doi.org/10.21010/ajtcamv15i3.2.

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Dunal) A. Rich, (herein called XYA), family Annonaceae, commonly known as “Guinea pepper”, “Ethiopian pepper” or “Negro pepper”, are widely used in traditional African medicines to treat a wide array of diseases including malaria, fungal infections, rheumatism, arthritis, etc. Scientific investigations have ascribed the following activities to the fruits of XYA; anti-diabetic, anti-inflammatory, antimicrobial, antiplasmodial, analgesic, anti-nociceptive, anti-proliferative, spermatogenic and neuropharmacological effects. The main active principle reported is xylopic acid (XA), a kaurene diterp
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Osafo, Newman, David Darko Obiri, Kwabena Owusu Danquah, Laslie Brian Essel, and Aaron Opoku Antwi. "Potential effects of xylopic acid on acetic acid-induced ulcerative colitis in rats." Turkish Journal of Gastroenterology 30, no. 8 (2019): 732–44. http://dx.doi.org/10.5152/tjg.2019.18389.

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Alolga, Raphael N., Assogba G. Assanhou, and Vitus Onoja. ") QUANTIFICATION OF XYLOPIC ACID AND CHROMATOGRAPHIC FINGERPRINT EVALUATIONS OF THE DRIED FRUITS OF XYLOPIA AETHIOPICA FROM FOUR AFRICAN COUNTRIES." African Journal of Traditional, Complementary and Alternative medicines 15, no. 3 (2018): 18–26. http://dx.doi.org/10.21010/ajtcam.v15i3.2.

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Osafo, N., and DD Obiri. "Anti-inflammatory and anti-anaphylactic activity of xylopic acid isolated from the dried fruit of Xylopia aethiopica in mice." Planta Medica 81, S 01 (2016): S1—S381. http://dx.doi.org/10.1055/s-0036-1596165.

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Dissertations / Theses on the topic "Xylopic acid"

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Esuon, Francis. "Extraction and Characterization of Xylopic Acid from Xylopia aethiopica." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etd/1171.

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Ongoing efforts to incorporate traditional or herbal medicine practice into the main stream healthcare delivery system of Ghana has led to increased research to isolate, identify, and characterize the active ingredients in these herbal products. It has also led to the development of semi-synthetic drugs and pharmacologically-active compounds. Essential oils from different parts of Xylopia aethiopica, a plant of Africa, showed various degrees of anti bacterial activity. The activity has been attributed to the presence of Xylopic acid the major diterpene component of the fruit oil extract. This
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Melo, Gabriela Muniz de Albuquerque. "Avaliação da atividade antinociceptiva e antiinflamatória de dois diterpenos e extratos da casca do caule de Xylopia langsdorffiana (Annonaceae)." Universidade Federal de Alagoas, 2009. http://repositorio.ufal.br/handle/riufal/925.

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This study describes the results of the study of the antinociceptive and antiinflammatory activity of ethanolic extract (EEt) and chloroform (ECl) from Xylopia langsdorffiana St-Hil & Tul and the diterpenes acid labda-8(17),12E,14-trien-18-oic (XL) and acid ent-7α-acetoxytrachyloban-18-oic (XLC) of these isolates, respectively. Substances (XL and XLC, 300 μmol/Kg, i.p) and extracts (EEt and ECl, 100 mg/Kg, i.p.) inhibited significantly the number of abdominal writhes when compared to control. To evaluate the power and effectiveness of the substances XL, XLC and dipyrone (300 μmo
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Conference papers on the topic "Xylopic acid"

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Boakye, YD, E. Heiss, and C. Agyare. "Bioactivity screening for xylopic acid, geraniin and its gut metabolites, ellagic acid and urolithin A, in cell based assays." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608576.

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