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1

Holmes, Cat, John Guenther, Gavin` Morris, et al. "Researching School Engagement of Aboriginal Students and Their Families from Regional and Remote Areas Project." Australian and International Journal of Rural Education 34, no. 1 (2024): 145–51. http://dx.doi.org/10.47381/aijre.v34i1.730.

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Over the last few years, attendance rates in remote schools have fallen, and Year 12 completions have also dropped. We are not sure why this is, though events like COVID-19, floods and other natural disasters have not made it easy. The case study presented here was part of a bigger project that sought to understand what people in remote schools and the communities they are in think makes a difference to attendance and Year 12 completion. This case study outlines the findings specific to one of the four case study sites, namely, Yipirinya School on Arrernte Country in Mparntwe (Alice Springs).
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2

Murphy, Karen J., Kathryn A. Dyer, Belinda Hyde, et al. "Long-Term Adherence to a Mediterranean Diet 1-Year after Completion of the MedLey Study." Nutrients 14, no. 15 (2022): 3098. http://dx.doi.org/10.3390/nu14153098.

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Mediterranean populations enjoy the health benefits of a Mediterranean diet (MedDiet), but is it feasible to implement such a pattern beyond the Mediterranean region? The MedLey trial, a 6-month MedDiet intervention vs habitual diet in older Australians, demonstrated that the participants could maintain high adherence to a MedDiet for 6 months. The MedDiet resulted in improved systolic blood pressure (BP), endothelial dilatation, oxidative stress, and plasma triglycerides in comparison with the habitual diet. We sought to determine if 12 months after finishing the MedLey study, the participant
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3

Foley, Michael Paul, Scott Michael Hasson, and Eydie Kendall. "Effects of a Translational Community-Based Multimodal Exercise Program on Quality of Life and the Influence of Start Delay on Physical Function and Quality of Life in Breast Cancer Survivors: A Pilot Study." Integrative Cancer Therapies 17, no. 2 (2017): 337–49. http://dx.doi.org/10.1177/1534735417731514.

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The purpose of this investigation was 2-fold: (1) to investigate the effects of a translational 12-week community-based multimodal exercise program on quality of life (QoL) in breast cancer survivors (BCS) and (2) to examine the influence of a start delay on physical function and QoL in BCS. Fifty-two female BCS completed a 12-week program consisting of 90-minute supervised exercise sessions at a frequency of 2 supervised sessions per week. Exercise sessions consisted of three 30-minute components: (1) aerobic conditioning, (2) resistance exercise training, and (3) balance and flexibility trai
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4

Asriyah, Faiqotul. "Upaya Meningkatkan Prestasi Belajar IPA melalui Model Pembelajaran Kooperatif Tipe Group Investigation di MIN 5 Gunungkidul." Jurnal Pendidikan Madrasah 6, no. 2 (2021): 201–6. http://dx.doi.org/10.14421/jpm.2021.62-12.

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This research aims to find out the improvement of IPA subject learning achievement through a Group Investigation type cooperative learning model. The study was conducted at MIN 5 Gunungkidul with the research subjects of students of class VI of the 2017/2018 School Year. The study uses class action methods including planning, execution, observation, test and documentation activities. The results showed the use of the Group Investigation model can improve IPA learning achievement as evidenced by the average grade in the student class in pre-cycle activities of 69.47 with learning completion of
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5

Lamb, Stephen. "Completing School in Australia: Trends in the 1990s." Australian Journal of Education 42, no. 1 (1998): 5–31. http://dx.doi.org/10.1177/000494419804200102.

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AFTER a period of dramatic growth in school completion in Australia, rates of school retention have begun to decline. At its peak in 1992 the national rate of retention to Year 12 was approximately 77 per cent. By 1995 the rate had fallen to 72 per cent. The aim of this paper is to document state, system, and social differences in the recent downturn in school completion rates in Australia. Data from the Australian Bureau of Statistics and from the Australian Youth Survey are used to look at patterns across states, school systems, geographical locations, social backgrounds, and by sex. The res
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6

McKay, Rana R., Kathryn P. Gray, Julia H. Hayes, et al. "Results of a phase II trial of docetaxel (DOC), bevacizumab (BEV), and androgen deprivation therapy (ADT) for biochemical relapse (BCR) after definitive local therapy for prostate cancer (PC)." Journal of Clinical Oncology 32, no. 4_suppl (2014): 54. http://dx.doi.org/10.1200/jco.2014.32.4_suppl.54.

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54 Background: Despite primary treatment for localized PC, 20-30% of men experience a BCR, detected by a rise in prostate-specific antigen (PSA). Though 30% of these patients develop metastatic disease, the optimal treatment of men with BCR has yet to be determined. In this trial, we evaluate the efficacy of DOC, BEV, and ADT for men with BCR after local therapy for PC. Methods: 41 men with a BCR and PSA doubling time of ≤10 months (mos) were enrolled. Patients received 4 cycles of DOC (75 mg/m2) every 3 weeks, 8 cycles of BEV (15 mg/kg) every 3 weeks, 18 mos of a luteinizing-hormone releasing
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7

Scott, Anthony M., Matthew C. Callier, Madison Lashley, David A. Cole, and Paul S. Dale. "A 12-Year Single-Institution Experience with Accelerated Partial Breast Irradiation." American Surgeon 84, no. 8 (2018): 1261–63. http://dx.doi.org/10.1177/000313481808400832.

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Accelerated partial breast irradiation (APBI) using the implanted brachytherapy device MammoSite® was approved for routine use by the Food and Drug Administration in 2002. The American Society of Breast Surgeons MammoSite® Breast Brachytherapy Registry served as a guideline for our institution to begin offering this treatment in 2005. This report reviews our available data to provide an analysis of patient outcomes over 12 years of use at a single institution. A retrospective review was conducted of records of 150 patients who underwent APBI or attempted APBI after breast-sparing surgeries bet
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8

Khan, Imran A., Parthasarathi Ramakrishnan, Rajapandian Subbaiah, et al. "Stump appendicitis single centre experience: a retrospective study." International Surgery Journal 7, no. 6 (2020): 1899. http://dx.doi.org/10.18203/2349-2902.isj20202403.

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Background: Appendicectomy is the most common surgical procedure done for acute appendicitis worldwide. However, one among 50000 appendicectomy patients may present with recurrent abdominal pain, requiring hospitalization as stump appendicitis and may need completion appendicectomy. There are a few reports addressing management of stump appendicitis in the literature. Here we present our experience of laparoscopic completion appendicectomy over ten-year duration.Methods: A retrospective evaluation of records of appendicectomy from January 2008 to December 2018. All patients who had stump appen
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9

Datta, Diva, Shivani Goyal, Robin Kaushik, and Simrandeep Singh. "Completion cholecystectomy for residual gallbladder: A re-emerging problem in the era of safe cholecystectomy." Hellenic Journal of Surgery 93, no. 2 (2023): 91–93. http://dx.doi.org/10.59869/23017.

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Incomplete gallbladder removal usually leads to residual gallbladder, which can act as a nidus for stone formation in later life. Stump cholecystitis is a condition in which, such a large gallbladder remnant left after subtotal cholecystectomy becomes inflamed. When this happens, a completion cholecystectomy is advised. We present a rare case of residual gall bladder in a 44-year-old woman who underwent a subtotal cholecystectomy procedure 12 years ago.
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10

Kirwan, Morwenna, Kylie Gwynne, Thomas Laing, Mellissa Hay, Noureen Chowdhury, and Christine L. Chiu. "Can Health Improvements from a Community-Based Exercise and Lifestyle Program for Older Adults with Type 2 Diabetes Be Maintained? A Follow up Study." Diabetology 3, no. 2 (2022): 348–54. http://dx.doi.org/10.3390/diabetology3020025.

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Background: Older people consistently report a desire to remain at home. Beat It is a community-based exercise and lifestyle intervention that uses evidence-based strategies to assist older people with type 2 diabetes mellitus (T2DM) to improve physical and functional fitness, which are crucial to maintain independence. This follow up, real-world study assessed the efficacy of Beat It and whether older adults with T2DM were able to maintain improvements in physical activity, waist circumference and fitness one year post completion. Methods: We have previously reported methods and results of sh
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11

Lindberg, Louise, Martina Persson, Pernilla Danielsson, Emilia Hagman, and Claude Marcus. "Obesity in childhood, socioeconomic status, and completion of 12 or more school years: a prospective cohort study." BMJ Open 11, no. 3 (2021): e040432. http://dx.doi.org/10.1136/bmjopen-2020-040432.

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ObjectivesChildren with obesity achieve lower educational level compared with normal-weight peers. Parental socioeconomic status (SES) impacts both a child’s academic achievement and risk of obesity. The degree to which the association between obesity and education depends on parental SES is unclear. Therefore, the primary aim is to investigate if individuals with obesity in childhood are less likely to complete ≥12 years of schooling, independently of parental SES. The secondary aim is to study how weight loss, level of education and parental SES are associated.DesignNationwide prospective co
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12

Fujiki, M., S. Miyamoto, S. Zenda, and M. Sakuraba. "Longitudinal and long-term effects of radiotherapy on swallowing function after tongue reconstruction." Journal of Laryngology & Otology 130, no. 9 (2016): 865–72. http://dx.doi.org/10.1017/s0022215116008720.

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AbstractObjective:This study evaluated the longitudinal and long-term effects of radiotherapy on swallowing function after tongue reconstruction.Methods:The study comprised 16 patients who had: undergone glossectomy and tongue reconstruction with free flap transfer, received adjuvant radiotherapy, and survived without recurrence for at least 1 year. Swallowing function, as indicated by tolerance of oral intake, was evaluated before radiotherapy, at radiotherapy completion, and at 6 and 12 months after radiotherapy completion.Results:Before radiotherapy, all patients could tolerate oral intake.
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13

Boyle, Jemma Megan, Angela Kuryba, Thomas E. Cowling, et al. "Real-world survival outcomes associated with completion of adjuvant chemotherapy for stage III colon cancer." Journal of Clinical Oncology 39, no. 15_suppl (2021): 3596. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.3596.

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3596 Background: The optimal duration of adjuvant combination chemotherapy administered to patients with stage III colon cancer is debated. Our study assessed the effect of completed chemotherapy cycles on 3-year colon cancer-specific mortality, as well as the effect of dose reduction and early discontinuation of oxaliplatin in patients with 100% completion, within a real-world population. Methods: 4,147 patients undergoing major resection between 01 June 2014 and 30 April 2017 with pathological stage III colon cancer in the English National Health Service were identified. Chemotherapy data we
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14

Bakhai, Smita, Aishwarya Bhardwaj, Parteet Sandhu, and Jessica L. Reynolds. "Optimisation of lipids for prevention of cardiovascular disease in a primary care." BMJ Open Quality 7, no. 3 (2018): e000071. http://dx.doi.org/10.1136/bmjoq-2017-000071.

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The 2013 American College of Cardiology/American Heart Association (ACC/AHA) guidelines focus on atherosclerotic cardiovascular disease (ASCVD) risk reduction, using a Pooled Cohort Equation to calculate a patient’s 10-year risk score, which is used to guide initiation of statin therapy. We identified a gap of evidence-based treatment for hyperlipidaemia in the Internal Medicine Clinic. Therefore, the aim of this study was to increase calculation of ASCVD risk scores in patients between the ages of 40 and 75 years from a baseline rate of less than 1% to 10%, within 12 months, for primary preve
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15

Haidar, Cyrine E., James M. Hoffman, Roseann S. Gammal, Mary V. Relling, and Kristine R. Crews. "Development of a postgraduate year 2 pharmacy residency in clinical pharmacogenetics." American Journal of Health-System Pharmacy 74, no. 6 (2017): 409–15. http://dx.doi.org/10.2146/ajhp160174.

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Abstract Purpose The structure and development of an innovative, ASHP-accredited postgraduate year 2 (PGY2) clinical pharmacogenetics residency program are described. Summary A 12-month PGY2 clinical pharmacogenetics residency was created at St. Jude Children’s Research Hospital in accordance with the ASHP standards for advanced practice residencies. The purpose of this 12-month residency program is to prepare pharmacy residents to implement pharmacogenetics in clinical practice. The program helps residents develop expertise in the science of pharmacogenetics as well as an understanding of tra
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16

Leung, Jessica, Elizabeth B. Gray, Tara Anderson, Sarah M. Sharkey, and Kathleen L. Dooling. "07. Recombinant Zoster Vaccine (RZV) Second-Dose Completion in Adults Age 50‒64 Years in the United States." Open Forum Infectious Diseases 8, Supplement_1 (2021): S127. http://dx.doi.org/10.1093/ofid/ofab466.210.

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Abstract Background In 2018, CDC recommended a highly efficacious adjuvanted recombinant zoster vaccine (RZV, Shingrix) as a 2-dose series for prevention of herpes zoster (HZ) for immunocompetent persons age ≥50 years, with the 2nd dose recommended 2–6 months after the 1st dose. Among Medicare beneficiaries, 2-dose series completion 6 months and 12 months post initiation was 78% and 86%, respectively. Here we estimate the proportion of adults age 50–64 years who completed the 2-dose RZV series within 6 or 12 months after receiving their 1st dose, by using two administrative claims databases. M
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17

Callander, Emily J., Deborah J. Schofield, Rupendra N. Shrestha, and Simon J. Kelly. "Sufficient education attainment for a decent standard of living in modern Australia." Journal of Social Inclusion 3, no. 1 (2012): 7–20. http://dx.doi.org/10.36251/josi39.

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Education attainment will impact upon an individual’s capacity to engage in the labour force, their living standards and hence their poverty status. As such, education should be included in measures of poverty. However, it is not known what a sufficient level of education to have a decent standard of living is. Using the 2003 Survey of Disability, Ageing and Carers different levels of education attainment were tested for their association with labour force participation and income. Based upon this, it was concluded that Year 12 or higher is a sufficient level of education attainment for 15 to
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18

Kennedy, Mary A., Lauren V. Fortington, Matt Penney, Nicolas H. Hart, Pierre A. d’Hemecourt, and Dai Sugimoto. "Running Marathons in High School: A 5-Year Review of Injury in a Structured Training Program." International Journal of Environmental Research and Public Health 20, no. 5 (2023): 4426. http://dx.doi.org/10.3390/ijerph20054426.

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Objective: The aim in this study was to quantify the number, nature, and severity of injuries sustained by male and female high school students who took part in a running training program that culminated in the completion of a half or full marathon. Design: This study is a retrospective clinical audit. Methods: Injury reports from high school students (grades 9–12) who participated in a half or full marathon 30-week progressive training program comprising four training days per week (three running days and one cross-training day) were reviewed. The number of runners completing a marathon, toge
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19

Thies, Wolf-Ruediger, Thomas Breymann, Dietmar Boethig, Ute Blanz, Hans Meyer, and Reiner Koerfer. "Results of staged reconstruction for hypoplasia of the left heart: an experience of 12 years from one institution." Cardiology in the Young 13, no. 6 (2003): 509–18. http://dx.doi.org/10.1017/s1047951103001094.

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Background:We reviewed our 12-year experience with staged reconstruction for hypoplasia of the left heart, examining the results of each surgical step and the impact of the year of the Norwood operation on survival. We compared survival of patients with hypoplasia of the left heart subsequent to completion of the Fontan circulation to survival of patients with a dominant left ventricle undergoing a Fontan procedure.Patients:Between 1989 and 2001, we performed a first stage procedure in 89 patients. Their median age was 9 days, with a range from 2 to 140 days, and the median weight was 3.4 kg,
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20

Becktell, Kerri, Rachel Phelan, Debra Schmidt, et al. "Developmental differences in health-related quality of life (HRQL) in adolescent and young adult (AYA) survivors of childhood cancer." Journal of Clinical Oncology 37, no. 15_suppl (2019): e21524-e21524. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e21524.

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e21524 Background: AYAs experience many distinct periods of developmental transition within this life stage. AYA survivors of childhood cancer are at risk for chronic physical and psychosocial health conditions due to treatment-related exposures. Few studies have evaluated HRQL differences that may exist among developmental subgroups of AYA cancer survivors. This study examined HRQL differences across AYA developmental subgroups (early teens 12-14 years; late teens 15-17; emerging adults 18-24; young adults 25-39) of long term childhood cancer survivors. Methods: Cancer survivors ages 12-39 ye
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21

Patterson, Brandon J., Chi-Chang Chen, Catherine B. McGuiness, Lisa I. Glasser, Kainan Sun, and Philip O. Buck. "17. Assessment of Recombinant Zoster Vaccine Second Dose Completion in the United States." Open Forum Infectious Diseases 7, Supplement_1 (2020): S31. http://dx.doi.org/10.1093/ofid/ofaa439.062.

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Abstract Background Recombinant Zoster Vaccine (RZV) was licensed in the United States (US) in October 2017 for the prevention of herpes zoster in adults ≥ 50 years of age (YOA). The vaccine is administered in a two-dose sequence with a 2- to 6-month interval; however, the Center for Disease Control & Prevention has advised against restarting a series after the prescribed window. This study describes an assessment of 2nd dose completion and compliance of RZV in the US. Methods Primary analysis was conducted on a cohort ≥ 50 YOA who received an initial RZV dose between October 2017 and Sept
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22

Henrikson, Nora B., Weiwei Zhu, Lauren Baba, et al. "Outreach and Reminders to Improve Human Papillomavirus Vaccination in an Integrated Primary Care System." Clinical Pediatrics 57, no. 13 (2018): 1523–31. http://dx.doi.org/10.1177/0009922818787868.

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This study evaluated the impact of health system–based outreach and reminders on human papillomavirus (HPV) vaccine series initiation and completion. Parents of 10 to 12 year olds (n = 1805) were randomized to receive either (1) an outreach letter and brochure recommending HPV vaccination followed by automated HPV vaccine reminders or (2) usual care. We interviewed a subset of 50 parents to assess program acceptability. Outcomes were HPV vaccine initiation during the study period and on-time series completion. Rates of HPV vaccine initiation during the study period (July 2015 to August 2016) w
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23

Mertin, Peter, Caroline Dibnah, Vivienne Crosbie, and Richard Bulkeley. "Using North American Instruments with British Samples: Norms for the Revised Children's Manifest Anxiety Scale in the UK." Child Psychology and Psychiatry Review 6, no. 3 (2001): 121–26. http://dx.doi.org/10.1017/s1360641701002520.

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The Revised Children's Manifest Anxiety Scale is a widely used assessment tool, but it is questionable whether the North American norms are applicable to a British population. The scale was administered to 575 English children aged 8–12 years. Means were computed by age and gender and compared to the published North American norms. English males reported less anxiety than American males in most age groups, while 8-year-old English girls reported less anxiety than 8-year-old American girls. The language used in the Scale caused some difficulties, suggesting that the Scale might be better used i
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24

Németh, Erzsébet, and Botond-Géza Kálmán. "A gyerekkori pénzügyi személyiség előre definiált faktorai: I.rész, belső konzisztenciavizsgálat." PedActa 13, no. 1 (2023): 9–16. http://dx.doi.org/10.24193/pedacta.13.1.2.

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In 2018, the Money Compass Foundation has published an online financial personality test for 12-14 year olds in Hungary. Completion is voluntary, and after completing the test, respondents receive an immediate assessment of their financial personality traits based on a predefined framework. The purpose of the testing is to learn about and develop young people's self-knowledge and financial awareness. The evaluation highlights the beneficial behaviours of the respondent and draws attention to the areas where the achieved results can be further improved. The test was completed by 15,933 responde
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25

Agana-Norman, Denny Fe G., Monica Martinez Martinez, Manjushree Shanmugasundaram, and Abbey B. Berenson. "Understanding Barriers to Human Papillomavirus Vaccination among Parents of 9–10-Year-Old Adolescents: A Qualitative Analysis." Vaccines 12, no. 3 (2024): 245. http://dx.doi.org/10.3390/vaccines12030245.

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HPV vaccination rates remain low among US adolescents, with only 54% completing the series in 2019. The vaccine is recommended at age 11–12 but can be given as early as age 9. Although it has been found that offering the vaccine earlier improves completion rates by age 13, parents remain reluctant to allow their younger children to initiate this vaccine. The purpose of this study was to better understand parental beliefs regarding receipt of the HPV vaccine among their children at ages 9–10. A 40 min phone interview was completed with 21 participants who were asked about their vaccine viewpoin
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26

Burykin, Alexey A. "Календарный 12-летний животный цикл в фольклоре калмыков и других народов Азии". Монголоведение (Монгол судлал) 12, № 4 (2020): 679–91. http://dx.doi.org/10.22162/2500-1523-2020-4-679-691.

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Introduction. The work deals with folklore stories about the 12-year animal calendar cycle once adopted by Kalmyks and other peoples of Asia, such as Mongols, Buryats, Altaians, Tuvans, etc. Goals. The paper focuses on the shaping of the 12-year-old animal cycle and roles played by traditional folklore animal characters in its formation. The paper defines impacts certain supreme characters made on the establishment of such calendar, the one for Mongols being the Buddha himself. Another distinctive feature of narratives about animals’ participation in the completion of the calendar is that spec
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27

Strickland, P. Andrew, Scott M. Bisping, and Hunter R. Hatcher. "Validation of Annulus Formation in Golden Shiner Otoliths." Journal of Fish and Wildlife Management 11, no. 1 (2020): 258–62. http://dx.doi.org/10.3996/082019-jfwm-069.

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Abstract Golden Shiner Notemigonus crysoleucas is found in many lakes and ponds across the southeastern United States. Though it is a common species, otolith age validation methods have not been published. The objective of this study was to confirm annulus formation in lapillar otoliths of Golden Shiners collected monthly from September 2015 through August 2016 in Lake Jackson, Florida (Leon County). We collected at least 12 individuals each month of similar length (168–249 mm; presumably of the same cohort) to document annulus formation throughout the year. We sacrificed a total of 177 indivi
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Opneja, Aman, Amit Rout, Joseph Abraham, Gurkirat Gill, and Kenneth David Miller. "Implantable intravenous devices (“ports”) as a survivorship issue." Journal of Clinical Oncology 34, no. 3_suppl (2016): 9. http://dx.doi.org/10.1200/jco.2016.34.3_suppl.9.

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9 Background: Women with early stage breast cancer often receive chemotherapy through implantable intravenous access devices (ports). There is little information on the duration of port use for breast cancer patients who have completed treatment. Methods: The EMR was searched for women who received adjuvant chemotherapy using a port for Stage I-III breast cancer between 2007- 2012. Data abstracted from the EMR included demographics, duration and type of chemotherapy, duration of port use and complications. Results: During the years 2007-2012, a total of 167 patients qualified for the study. 28
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29

Nakonechnyi, R. "Efficiency of tactical training of football players 11-12 years old using interactive tasks." Scientific Journal of National Pedagogical Dragomanov University. Series 15. Scientific and pedagogical problems of physical culture (physical culture and sports), no. 9(154) (October 3, 2022): 67–74. http://dx.doi.org/10.31392/npu-nc.series15.2022.9(154).16.

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In the article, a comparative analysis of tactical training programs for football players aged 11-12 years (at the stage of preliminary basic training) is carried out using traditional (training program for football players of the "Rukh" Lviv Academy) and author's approaches (experimental program for tactical training of football players using interactive tasks) to build them content. The author's program of tactical training of 11-12-year-old football players is generally created on the basis of preliminary research. In particular, the data obtained: before the beginning, during and after the
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30

Gallagher, A., J. Sheridan, G. Doherty, H. Mulcahy, and G. Cullen. "P301 Outcomes following colectomy for patients with Ulcerative Colitis, ten years of data from a tertiary referral centre." Journal of Crohn's and Colitis 17, Supplement_1 (2023): i445—i446. http://dx.doi.org/10.1093/ecco-jcc/jjac190.0431.

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Abstract Background Patients who undergo subtotal colectomy for Ulcerative Colitis (UC) have a persistent risk of colorectal cancer (CRC) in the retained rectum and this increases overtime. There are currently no guidelines for rectal surveillance in this group. We aimed to assess the outcome following colectomy for patients with UC over a ten year period. Methods We conducted a retrospective analysis of patients with UC who underwent colorectal surgery in a tertiary referral centre. The Hospital In-Patient Enquiry system and the St Vincent's Hospital IBD Database were used to identify patient
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Koczwara, Bogda, Shahid Ullah, M. Nazim Abbas, et al. "A prospective study of anti-mullerian hormone (AMH) as a predictor of chemotherapy-induced menopause." Journal of Clinical Oncology 37, no. 15_suppl (2019): e23076-e23076. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e23076.

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e23076 Background: Chemotherapy-induced premature menopause is a distressing side effect of cancer treatment. Currently there are no validated tools to predict the loss of ovarian function. Anti-Mullerian hormone (AMH) in healthy women correlates with ovarian reserve and predicts menopause but its utility in chemotherapy-treated patients is underexplored. We examined the utility of AMH levels as a predictor of chemotherapy-induced amenorrhea at 1-year post chemotherapy - a reliable surrogate for chemotherapy-induced menopause. Methods: Premenopausal women, 45 years or younger, about to receive
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32

Haydek, J., A. Oonk, D. Cheng, et al. "P691 Disparate care: rates of treat to target among patients with inflammatory bowel disease." Journal of Crohn's and Colitis 17, Supplement_1 (2023): i821—i823. http://dx.doi.org/10.1093/ecco-jcc/jjac190.0821.

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Abstract Background Inflammatory bowel diseases (IBD) therapies are limited by low response rates and risks of loss of response. Treat to target (T2T) algorithms aim to maximize the benefit of therapies by establishing a framework for assessing patient reported outcomes, biochemical evaluation (C-reactive protein (CRP) or fecal calprotectin (FC)), and structural assessment via endoscopy or enterography. There are limited data on adoption rates of T2T in real-world clinical practice. We aimed to describe rates of T2T utilization in a large regional medical system in the United States. Methods A
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33

Humphreys, Leanne, John Westerink, Leah Giarratano, and Robert Brooks. "An Intensive Treatment Program for Chronic Posttraumatic Stress Disorder: 2-Year Outcome Data." Australian & New Zealand Journal of Psychiatry 33, no. 6 (1999): 848–54. http://dx.doi.org/10.1046/j.1440-1614.1999.00640.x.

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Objective: The present study evaluates the efficacy of a closed-cohort treatment program for chronic posttraumatic stress disorder (PTSD). Method: The treatment orientation was a combined approach involving cognitive behaviour therapy and pharmacotherapy. Treatment involved an inpatient phase of 4 weeks, with group and individual follow-up sessions of at least 6-month duration. The treatment population consisted largely of Australian Vietnam veterans. Standardised psychometric measures were obtained pre-treatment, on completion of the residential phase; and at 6, 12 and 24 months post discharg
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Ashina, Messoud, Caroline Roos, Lily Qian Li, et al. "Long-term treatment with lasmiditan in patients with migraine: Results from the open-label extension of the CENTURION randomized trial." Cephalalgia 43, no. 4 (2023): 033310242311617. http://dx.doi.org/10.1177/03331024231161745.

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Background Following the CENTURION phase 3 randomized controlled trial’s four-month double-blind phase, this 12-month open-label extension collected data for up to one year about dose optimization, patterns of use, migraine-related disability, and quality of life during lasmiditan treatment. Methods Migraine patients ≥18 years completing the double-blind phase and treating ≥3 migraine attacks could continue into the 12-month open-label extension. The initial oral lasmiditan dose was 100 mg; the dose could subsequently be adjusted to 50 mg or 200 mg at the investigator’s discretion. Results 477
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Singh, Itu, Madhvi Ahuja, Mallika Lavania, et al. "Efficacy of fixed duration multidrug therapy for the treatment of multibacillary leprosy: A prospective observational study from Northern India." Indian Journal of Dermatology, Venereology and Leprology 89 (September 30, 2022): 226–32. http://dx.doi.org/10.25259/ijdvl_915_2021.

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Background: In endemic regions of several countries, the prevalence of leprosy has not come down to the level of elimination. On the contrary, new cases are being detected in large numbers. Clinically, it is frequently noted that despite completion of multibacillary multidrug therapy for 12 months, the lesions remain active, especially in cases with high bacteriological indices. Aim: The present study focused on finding out the viable number of Mycobacterium leprae during the 12-month regimen of multibacillary multidrug therapy, at six and 12 months intervals and, attempting to determine their
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Sellar, Christopher M., Gordon J. Bell, Robert G. Haennel, Heather-Jane Au, Neil Chua, and Kerry S. Courneya. "Feasibility and efficacy of a 12-week supervised exercise intervention for colorectal cancer survivors." Applied Physiology, Nutrition, and Metabolism 39, no. 6 (2014): 715–23. http://dx.doi.org/10.1139/apnm-2013-0367.

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Exercise training improves health-related physical fitness and patient-reported outcomes in cancer survivors, but few interventions have targeted colorectal cancer (CRC) survivors. This investigation aimed to determine the feasibility and efficacy of a 12-week supervised exercise training program for CRC survivors. Feasibility was assessed by tracking participant recruitment, loss to follow-up, assessment completion rates, participant evaluation, and adherence to the intervention. Efficacy was determined by changes in health-related physical fitness. Over a 1-year period, 72 of 351 (21%) CRC s
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Watson, Jane, Suzie Wright, Kim Beswick, Jeanne Maree Allen, Ian Hay, and Neil Cranston. "Community Beliefs about Rural and Regional Education and Students' School Completion." Australian and International Journal of Rural Education 27, no. 3 (2022): 55–72. http://dx.doi.org/10.47381/aijre.v27i3.185.

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School completion to the end of Year 12 in rural, regional, and disadvantaged communities is an acknowledged challenge in Australia and internationally. This research reports the beliefs of 86 rural and regional community leaders in the Australian state of Tasmania. A survey on issues associated with students' school completion was designed specifically for community members, and responded to by the study participants. Findings that emerged from the data analysis included that participants were on average quite positive about the capability of students in the community and the potential for bu
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Santos, Marisa D., Manuel T. Gomes, Filipa Moreno, Anabela Rocha, and Carlos Lopes. "17-Week Delay Surgery after Chemoradiation in Rectal Cancer with Complete Pathological Response." Case Reports in Surgery 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/816491.

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Neoadjuvant chemoradiation (CRT) followed by curative surgery still remains the standard of care for locally advanced rectal cancer (LARC). The main purpose of this multimodal treatment is to achieve a complete pathological tumor response (ypCR), with better survival. The surgery delay after CRT completion seems to increase tumor response and ypCR rate. Usually, time intervals range from 8 to 12 weeks, but the maximum tumor regression may not be seen in rectal adenocarcinomas until several months after CRT. About this issue, we report a case of a 52-year-old man with LARC treated with neoadjuv
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Hand, C. J., and G. E. D. Howell. "Three Year Review Following Bone Anchor Repair of Acute Biceps Tendon Insertion Rupture." Journal of The Royal Naval Medical Service 87, no. 2 (2001): 113–15. http://dx.doi.org/10.1136/jrnms-87-113.

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AbstractThree patients with acute biceps brachii tendon insertion ruptures were treated (less than 7 days post injury) using bone anchor anatomical repair. Dynamometer assessment of strength in both limbs was performed after completion of rehabilitation and again at 3.3 years after surgery.All patients were male, age 34, 35 and 53 years. Early isokinetic assessment was performed at 6, 7 and 12 months post surgery and medium assessment at 3.3 years post surgery. A full range of movement was achieved at early assessment and maintained into medium term assessment. All patients returned to their f
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Hand, C. J., and G. E. D. Howell. "Three Year Review Following Bone Anchor Repair of Acute Biceps Tendon Insertion Rupture." Journal of The Royal Naval Medical Service 87, no. 2 (2001): 113–15. http://dx.doi.org/10.1136/jrnms-87-113.

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AbstractThree patients with acute biceps brachii tendon insertion ruptures were treated (less than 7 days post injury) using bone anchor anatomical repair. Dynamometer assessment of strength in both limbs was performed after completion of rehabilitation and again at 3.3 years after surgery.All patients were male, age 34, 35 and 53 years. Early isokinetic assessment was performed at 6, 7 and 12 months post surgery and medium assessment at 3.3 years post surgery. A full range of movement was achieved at early assessment and maintained into medium term assessment. All patients returned to their f
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Marcotte, Lauren, Cindy Barha, and Teresa Liu-Ambrose. "CARDIOVASCULAR RISK MODERATES THE EFFECT OF RESISTANCE TRAINING ON PHYSICAL PERFORMANCE IN OLDER ADULT WOMEN." Innovation in Aging 3, Supplement_1 (2019): S645. http://dx.doi.org/10.1093/geroni/igz038.2396.

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Abstract We aimed to examine whether the Framingham Cardiovascular Risk Profile Score (FCRP) moderates the effect of progressive resistance training (RT) on mobility in older adult women. This is an exploratory analysis of a single-blind, 12-month randomized controlled trial in 155 omen, aged 65 to 75 years old, who were randomized to: 1x/week progressive RT; or 2x/week progressive RT program; or 2x/week balance and tone (BAT). At baseline and trial completion, mobility was measured using the Short Physical Performance Battery (SPPB). The SPPB is a composite measure of usual gait speed, standi
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Rojanasarot, Sirikan, Angeline M. Carlson, Wendy L. St. Peter, Pinar Karaca-Mandic, Julian Wolfson, and Jon C. Schommer. "Translational Effect of Provider-Focused, Multi-State, Multi-Clinic Asthma Care Quality Improvement Program on Patient-Level Health Care Costs." Journal of Primary Care & Community Health 12 (January 2021): 215013272110002. http://dx.doi.org/10.1177/21501327211000246.

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Introduction/Objectives: Enhancing Care for Patients with Asthma (ECPA), a year-long provider-focused, multi-state, multi-clinic quality improvement program, decreased avoidable utilizations among patients with asthma, but its effects on health care expenditures were not determined. This study examined the translational and sustainable effects of improved care through ECPA on individual-level total health care costs due to asthma. Methods: We conducted a retrospective pretest-posttest quasi-experimental study in which attributed 1683 patients in a 12-month pre-ECPA implementation period served
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Ghia, Paolo, William G. Wierda, Paul M. Barr, et al. "Relapse after First-Line Fixed Duration Ibrutinib + Venetoclax: High Response Rates to Ibrutinib Retreatment and Absence of BTK Mutations in Patients with Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) with up to 5 Years of Follow-up in the Phase 2 Captivate Study." Blood 142, Supplement 1 (2023): 633. http://dx.doi.org/10.1182/blood-2023-187128.

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Background: CAPTIVATE (PCYC-1142) is a multicenter phase 2 study of ibrutinib + venetoclax as first-line treatment for CLL/SLL in 2 cohorts: minimal residual disease (MRD)-guided randomized-discontinuation (MRD cohort) and Fixed Duration (FD cohort). Results from the FD cohort with 4 years of follow-up (Barr, ASCO 2023) showed 4-year progression-free survival (PFS) and overall survival (OS) rates of 79% and 98%, respectively. After completing fixed-duration treatment, ibrutinib-based retreatment was allowed per protocol in patients with an indication for treatment after experiencing progressiv
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Roxburgh, Campbell SD, Paul Strombom, Patricio B. Lynn, et al. "Influence of timing of surgery on perioperative morbidity after neoadjuvant therapy for locally advanced rectal cancer." Journal of Clinical Oncology 36, no. 4_suppl (2018): 754. http://dx.doi.org/10.1200/jco.2018.36.4_suppl.754.

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754 Background: Timing of surgery following completion of neoadjuvant therapy (NT) for locally advanced rectal cancer (LARC) has important implications for treatment response. However, it was recently reported in the GRECCAR 6 trial that delayed surgery beyond 8 weeks from completion of NT is associated with increased complications. Within a cohort of LARC patients treated with NT (CRT alone, Total NT (TNT) and chemotherapy alone) we examine perioperative complications based on time from NT to surgery. Methods: Patients with Stage II/III LARC ≤15cm from the anal verge who received NT from 06/0
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Yamada, Takeshi, Keiji Koda, Hiroshi Yoshida, et al. "Occurrence of irreversible sinusoidal obstruction syndrome during adjuvant chemotherapy for colorectal cancer using oxaliplatin: A multi-center study." Journal of Clinical Oncology 37, no. 4_suppl (2019): 546. http://dx.doi.org/10.1200/jco.2019.37.4_suppl.546.

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546 Background: Oxaliplatin reduces the recurrence rate after curative surgery for stage III colorectal cancer. However, it can cause hepatic sinusoidal obstruction syndrome (SOS), an adverse effect that creates morbidity after liver resection for recurrence. SOS has conventionally been diagnosed by liver biopsy, which is invasive. We have reported that a 10% increase in splenic volume (SV) indicates SOS (J Surg Oncol 2017). In this multi-center study, we measured SV to evaluate SOS caused by adjuvant chemotherapy. Methods: This multi-center study included the participants of the FACOS study,
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Jabeen, Irum, Asim Khurshid, and Tariq Aziz. "Steroid sensitive nephrotic syndrome in children: Frequency of relapse during the first twelve months after completion of six months steroid therapy." Professional Medical Journal 27, no. 03 (2020): 558–62. http://dx.doi.org/10.29309/tpmj/2020.27.03.3571.

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Objectives: Nephrotic syndrome (NS) is described as the existence of nephrotic-range proteinuria along with edema, hyperlipidemia and hypoalbuminemia. NS is estimated to be 15 time more frequent in children as compared to adults. Relapse is a major problem while managing nephrotic children. This study was aimed to find out the frequency of relapse in children with first episode of steroid sensitive nephrotic syndrome (SSNS) during the first 12 months, after completion of 6 months steroid therapy. Study Design: Descriptive case series study. Setting: Department of Paediatric Nephrology, The Chi
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Pilloni, Andrea, Matteo Saccucci, Gabriele Di Carlo, et al. "Clinical Evaluation of the Regenerative Potential of EMD and NanoHA in Periodontal Infrabony Defects: A 2-Year Follow-Up." BioMed Research International 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/492725.

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Introduction.The aim of this retrospective study was to compare the clinical efficacy of four different surgical techniques in promoting periodontal regeneration in patients with infrabony defects: open flap debridement, application of enamel matrix derivatives (EMD), nanohydroxyapatite (nanoHA) application, and combined nanoHA and EMD application. Probing attachment level (PAL), pocket depth (PD), and position of gingival margin at completion of therapy (REC) were measured.Materials and Methods.Data were collected from 64 healthy patients (34 women and 30 men, mean age 37,7 years). Clinical i
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Zhu, Yujun, and Susan Enguidanos. "Advance Directive Completion and Hospital Out-of-Pocket Expenditures." Innovation in Aging 5, Supplement_1 (2021): 568–69. http://dx.doi.org/10.1093/geroni/igab046.2185.

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Abstract Healthcare costs remain high at end of life. Although advance directives (AD) have been shown to improve care congruence with patients’ preferences and lower cost of healthcare services, little is known about the relationship between AD completion and hospital out-of-pocket costs. This study examined whether AD completion was associated with lower hospital out-of-pocket spending at end of life. We used the Health and Retirement Study participants who died between 2000 and 2014 (N=9,228) to examine the association through the use of a two-part analytic model that has been widely used i
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Yamamoto, Hiromasa, Junichi Soh, Norihito Okumura, et al. "Randomized phase II study of daily versus alternate-day administrations of S-1 for the elderly patients with completely resected pathological stage IA (tumor diameter > 2 cm)—IIIA of non-small cell lung cancer: Setouchi Lung Cancer Group Study 1201." PLOS ONE 18, no. 5 (2023): e0285273. http://dx.doi.org/10.1371/journal.pone.0285273.

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Background It is shown that the postoperative adjuvant chemotherapy for non-small cell lung cancer (NSCLC) was associated with survival benefit in an elderly population. We aimed to analyze the feasibility and efficacy of alternate-day S-1, an oral fluoropyrimidine, for adjuvant chemotherapy in elderly patients with completely resected pathological stage IA (tumor diameter > 2 cm) to IIIA (UICC TNM Classification of Malignant Tumours, 7th edition) NSCLC. Methods Elderly patients were randomly assigned to receive adjuvant chemotherapy for one year consisting of either alternate-day oral admi
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Taylor, Jennie, Michael Rabow, Susan Chang, et al. "QOLP-12. EMBEDDING OUTPATIENT PALLIATIVE CARE INTO NEURO-ONCOLOGY CLINIC – RESULTS FROM A ONE YEAR PILOT." Neuro-Oncology 22, Supplement_2 (2020): ii177. http://dx.doi.org/10.1093/neuonc/noaa215.737.

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Abstract BACKGROUND Glioblastoma (GBM) patients fall within NCCN and ASCO guidelines for early palliative care (PC). However, data suggests they are less likely than systemic cancers to be referred to PC and often later in their illness. This results in potential missed opportunities, both for improving symptom control and earlier completion of important tasks, like advance care planning. Data on how to best incorporate comprehensive PC into routine neuro-oncology (NO) patient care is needed. METHODS We piloted a program embedding a PC physician into UCSF’s NO clinic one half-day per week. NO
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