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Relevant bibliographies by topics / YWHAE

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Academic literature on the topic 'YWHAE'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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Journal articles on the topic "YWHAE"

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Sun, Ziqiao, and Xin-Gen Lei. "Evidence and Metabolic Implications for a New Non-Canonical Role of Cu-Zn Superoxide Dismutase." International Journal of Molecular Sciences 24, no. 4 (2023): 3230. http://dx.doi.org/10.3390/ijms24043230.

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Copper–zinc superoxide dismutase 1 (SOD1) has long been recognized as a major redox enzyme in scavenging superoxide radicals. However, there is little information on its non-canonical role and metabolic implications. Using a protein complementation assay (PCA) and pull-down assay, we revealed novel protein–protein interactions (PPIs) between SOD1 and tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta (YWHAZ) or epsilon (YWHAE) in this research. Through site-directed mutagenesis of SOD1, we studied the binding conditions of the two PPIs. Forming the SOD1 and YWHAE or YW

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Bjeije, Hassan, Bahram Mohammad Soltani, Mehrdad Behmanesh, and Mohammad Reza Zali. "YWHAE long non-coding RNA competes with miR-323a-3p and miR-532-5p through activating K-Ras/Erk1/2 and PI3K/Akt signaling pathways in HCT116 cells." Human Molecular Genetics 28, no. 19 (2019): 3219–31. http://dx.doi.org/10.1093/hmg/ddz146.

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AbstractYWHAE gene product belongs to the 14-3-3 protein family that mediates signal transduction in plants and mammals. Protein-coding and non-coding RNA (lncRNA) transcripts have been reported for this gene in human. Here, we aimed to functionally characterize YWHAE-encoded lncRNA in colorectal cancer-originated cells. RNA-seq analysis showed that YWHAE gene is upregulated in colorectal cancer specimens. Additionally, bioinformatics analysis suggested that YWHAE lncRNA sponges miR-323a-3p and miR-532-5p that were predicted to target K-Ras 3′UTR sequence. Overexpression of YWHAE lncRNA result

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Xu, Yan, Mariateresa Fulciniti, Matthew Ho та ін. "Dysregulated Translational Control Is a Central Feature of MM Mediated By 14-3-3ε Interactome Promoting Multiple Myeloma Cell Growth and Viability". Blood 132, Supplement 1 (2018): 3176. http://dx.doi.org/10.1182/blood-2018-99-118994.

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Abstract 14-3-3 proteins are chaperone and scaffold proteins that exert a widespread influence on cellular processes through binding to serine/threonine-phosphorylated residues on target proteins, forcing conformational changes or influencing their interactions with other molecules. Altered 14-3-3 expression is associated with development and progression of cancer. We therefore evaluated the status of all 14-3-3 isoforms in plasma cells disorders in publically available gene expression profiling (GEP) data. Using independent patient datasets, we observed a consistent higher expression of YWHAE

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Chen, Tao, and Shengrong Sun. "Molecular Mechanism of circRAPGEF5 in Regulating the Molecular Axis of microRNA-4712-5p/Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon Affecting Cellular Proliferation and Apoptosis in Mammary Cancer." Journal of Biomaterials and Tissue Engineering 11, no. 6 (2021): 1053–58. http://dx.doi.org/10.1166/jbt.2021.2499.

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To understand the molecular mechanism of circRAPGEF5, its effect on the proliferation and apoptosis of mammary cancer cells, and its regulatory effect on the molecular axis of miRNA-4712-5p/YWHAE. qRT-PCR and Western blot were used to test circRAPGEF5, miRNA-4712-5p, and YWHAE expression in mammary cancer and paracancerous tissues. The human mammary cancer cell, MDA-MB-231, was cultured in vitro, and pcDNA-NC, pcDNA-circRAPGEF5, anti-miRNA-NC, anti-miRNA-4712-5p, pcDNA-circRAPGEF5, and miRNA-NC, pcDNA-circRAPGEF5 were transfected into MDA-MB-231 cells with miRNA-4712-5p mimics. qRT-PCR and Wes

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Wen, Jin, Zhengwei Ma, Man J. Livingston, et al. "Decreased secretion and profibrotic activity of tubular exosomes in diabetic kidney disease." American Journal of Physiology-Renal Physiology 319, no. 4 (2020): F664—F673. http://dx.doi.org/10.1152/ajprenal.00292.2020.

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Tubular changes contribute to the development of renal pathologies in diabetic kidney disease (DKD), including interstitial fibrosis. It is unclear how tubular cells relay signals to interstitial fibroblasts. Recently, exosomes have been recognized as crucial mediators of intercellular communication. We hypothesized that exosomes secreted from tubular cells may stimulate fibroblasts for interstitial fibrosis in DKD. In this study, we isolated and purified exosomes from the renal cortex of DKD mice and high glucose-treated mouse proximal tubular cells. Compared with nondiabetic mice, exosome se

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Scheibner, Kara A., Brie Teaboldt, Mary Claire Hauer, and Curt I. Civin. "The Mir-23a∼Mir-27a∼Mir-24 Cluster Acts as a Tumor Suppressor In Leukemias by Post-Transcriptional Regulation of 14-3-3 Proteins." Blood 116, no. 21 (2010): 3145. http://dx.doi.org/10.1182/blood.v116.21.3145.3145.

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Abstract Abstract 3145 We and others have found that microRNAs (miRs) play major roles in normal hematopoietic differentiation, evidenced by the discovery of a small set of hematopoietic stem-progenitor cell (HSPC)-expressed miRs (HE-miRs) highly expressed in normal human CD34+ cells, which post-transcriptionally regulate specific mRNAs involved in hematopoiesis. Microarray data indicated that 1 of these HE-miRs, miR-27a (transcribed as part of the miR-23a cluster consisting of 3 coordinately transcribed miRs: miR-23a, miR-27a, miR-24-2) is absent or expressed at much lower levels in several h

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Subbaraya, Sneha, Sudha S. Murthy, and Sandhya Devi G. "Immunohistochemical and Molecular Characterization of Endometrial Stromal Sarcomas." Clinical Pathology 13 (January 2020): 2632010X2091673. http://dx.doi.org/10.1177/2632010x20916736.

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Introduction: Endometrial stromal sarcomas (ESSs) are rare and characterized by translocations t(7;17)(p15;q11.2) and t(10;17)(q22;p13), resulting in JAZF1-SUZ12 and YWHAE-FAM22 gene fusions used for defining low-grade (LG-ESS) and high-grade (HG-ESS) tumours. Aim: The objective of the study was to characterize ESSs using immunohistochemical and molecular markers. Material and Methods: Patients diagnosed as having ESSs between January 2014 and December 2018 were included in the study. The slides were reviewed along with a panel of immunohistochemical markers, CD10, cyclin D1, oestrogen recepto

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Kenny, Colin, David Grehan, Mevlut Ulas, et al. "Immunophenotype-Genotype Correlations in Clear Cell Sarcoma of Kidney—An Evaluation of Diagnostic Ancillary Studies." Pediatric and Developmental Pathology 23, no. 5 (2020): 345–51. http://dx.doi.org/10.1177/1093526620910658.

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Introduction The purpose of this study was to establish a reliable panel of antibodies for immunohistochemical corroboration of a diagnosis of clear cell sarcoma of kidney (CCSK), taking into consideration the various genotypic subsets of CCSK. Methods We conducted full genotypic analysis for evidence of YWHAE-NUTM2, BCOR internal tandem duplication (ITD), and BCOR-CCNB3 in 68 archival cases of CCSK and then immunostained all cases for CCND1, TLE1, and BCOR along with 63 control samples representing tumor types that may enter into the differential diagnosis of CCSK, including 7 congenital meso

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Khalilova, Z. L., A. G. Zainullina, A. R. Valiullina, G. G. Zakharova, R. G. Valinurov, and E. K. Khusnutdinova. "Association of YWHAE gene polymorphism with suicidal behavior." Russian Journal of Genetics 49, no. 6 (2013): 667–72. http://dx.doi.org/10.1134/s1022795413030095.

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Guizard, Maylis, Marie Karanian, Frédérique Dijoud, et al. "Neonatal Soft Tissue Sarcoma with YWHAE-NUTM2B Fusion." Case Reports in Oncology 12, no. 2 (2019): 631–38. http://dx.doi.org/10.1159/000502227.

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Neonatal soft tissues sarcoma is a rare entity that comprises heterogeneous types of tumors. In this article we describe a neonatal case of round-cell sarcoma with an YWHAE-NUTM2B fusion gene. The patient was treated just after birth with neoadjuvant chemotherapy, then surgical resection, but evolution was quickly fatal. This fusion transcript has been reported in endometrial stromal sarcomas and clear cells renal sarcomas but its description in small round-cell sarcomas is recent. To our knowledge, this is the first case report describing this translocation in a newborn patient with soft tiss

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Dissertations / Theses on the topic "YWHAE"

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Haßfeld, Jochen [Verfasser], Nicolai [Akademischer Betreuer] Miosge, Arndt [Gutachter] Schilling, and Rainer [Gutachter] Mausberg. "Der Einfluss von YWHAE auf das chondrogene Potenzial von chondrogenen Progenitorzellen / Jochen Haßfeld ; Gutachter: Arndt Schilling, Rainer Mausberg ; Betreuer: Nicolai Miosge." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2020. http://d-nb.info/1213520452/34.

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Detwiler, Ariana Claire. "Evidence for the Role of YWHA in Mouse Oocyte Maturation." Kent State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=kent1438019442.

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SAHU, MEHAR. "COMPUTATIONAL ANALYSIS OF POST TRANSLATIONAL MODIFICATIONS IN THE PATHOGENESIS OF ALZHEIMER'S DISEASE." Thesis, DELHI TECHNOLOGICAL UNIVERSITY, 2021. http://dspace.dtu.ac.in:8080/jspui/handle/repository/18405.

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Aim: Post-translational modifications like acetylation and ubiquitination share a common feature that they both act on lysine residue. Acetylation is responsible for transcriptional deregulation which further leads to mitochondrial dysfunction, autophagic pathway problems and DNA damage which ultimately leads to cell death. On the other hand, ubiquitination aids in degrading the accumulated toxic proteins. Thus, we aim to investigate the potential acetylation and ubiquitination sites in YWHAZ which is responsible for the pathogenesis of AD. Moreover, we aim to identify the impact of thes

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De, Santanu. "Protein 14-3-3 (YWHA) isoforms and their roles in regulating mouse oocyte maturation." Kent State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=kent1401803571.

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Gilker, Eva Adeline Gilker. "INTERACTIONS AND LOCALIZATION OF PROTEIN PHOSPHATASES, YWHA PROTEINS AND CELL CYCLE CONTROL PROTEINS IN MEIOSIS." Kent State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=kent1532699317257539.

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Lin, Mau-Ting. "Identification of frequent gains of DNA copy number and characterization of potential novel oncogenes in head and neck squamous cell carcinoma." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1196177703.

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Solf, Andrea. "Transkriptionelle Netzwerke der RAS-abhängigen, MEK-ERK- vermittelten Transformation." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2011. http://dx.doi.org/10.18452/16295.

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Transkriptionelle Netzwerke (Transkriptionsfaktoren, epigenetische Modulatoren und spezifische Zielgene) stellen die unterste Ebene der zellinternen Signalübertragung dar. Eingebettet in verschiedene stimulusabhängige Signalwege bedienen sich ihre Komponenten genetischer und epigenetischer Mechanismen, um Zielgene transkrip-tionell zu regulieren und Veränderungen der Chromatinstruktur hervorzurufen. In der vorliegenden Arbeit wurde die hierarchische Organisation und Zusam-mensetzung des MEK-ERK-abhängig gesteuerten transkriptionellen Netzwerks und seine Veränderung im Zuge der HRAS-vermittel

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Eisa, Alaa Abdulaziz. "ROLE OF 14-3-3 ETA AND EPSILON IN GAMETOGENESIS." Kent State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=kent1574096506246273.

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Haßfeld, Jochen. "Der Einfluss von YWHAE auf das chondrogene Potenzial von chondrogenen Progenitorzellen." Doctoral thesis, 2020. http://hdl.handle.net/21.11130/00-1735-0000-0005-13E4-4.

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Schultze, Frank Christian. "Durch Sirolimus induzierte frühe Veränderungen des Proteoms und Phosphoproteoms in humanen T-Lymphoblasten." Doctoral thesis, 2011. http://hdl.handle.net/11858/00-1735-0000-0006-B1B5-8.

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Book chapters on the topic "YWHAE"

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"YWHAE." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_104191.

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"YWHA1." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_104187.

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"YWHAA." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_104188.

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"YWHAD." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_104190.

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"YWHAG." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_104192.

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"YWHAH." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_104193.

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"YWHAQ." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_104194.

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"YWHAS." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_104195.

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"YWHAZ." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_104196.

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"YWHAB 14-3-3γ: 14-3-3gammma." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_104189.

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Conference papers on the topic "YWHAE"

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Boldura, Oana Mari, Jelena Savici, Calin Mircu, Cornel Balta, and Simona Marc. "VALIDATION OF REFERENCE GENES FOR RT-QPCR IN PORCINE OOCYTES CULTURED IN ANTIOXIDANT-ENRICHED MEDIA." In 24th SGEM International Multidisciplinary Scientific GeoConference 2024. STEF92 Technology, 2024. https://doi.org/10.5593/sgem2024v/4.2/s19.52.

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Reference genes are essential for normalising data in RT-qPCR experiments and are critical in reducing technical variability. This study aimed to identify and validate stable reference genes for accurate gene expression analysis in porcine oocytes matured in culture media supplemented with antioxidants. Five commonly used reference genes were assessed: PPIA, RPL4, GAPDH, YWHAZ, and TBP, [2, 3] in oocytes cultured under oxidative stress conditions induced by Vitamin C. The experiment involved four experimental groups, analyzed in triplicate using SYBR Green RT-qPCR. PPIA exhibited the lowest SE

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Chen, Ching-Hsien, Hsuan-Yu Chen, Sheng-Yi Lin, Meng-Feng Tsai, Sung-Liang Yu, and Jeremy Chen. "Abstract 3440: YWHAZ promotes slug transcription activity and lung cancer metastasis." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3440.

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Shi, Lingxue, Xiaohong Wang, Hongyan Gou, et al. "IDDF2022-ABS-0237 TMEM65 interacts with YWHAZ to promote gastric cancer progression." In Abstracts of the International Digestive Disease Forum (IDDF), Hong Kong, 2–4 September 2022. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2022. http://dx.doi.org/10.1136/gutjnl-2022-iddf.76.

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Menon, Roopika, Kerstin Rüenauver, Mario Deng, et al. "Abstract B97: Somatic copy number alterations by whole-exome sequencing reveals YWHAZ and PTK2 as potential therapeutic targets in castration-resistant prostate cancer." In Abstracts: AACR Special Conference on Tumor Invasion and Metastasis - January 20-23, 2013; San Diego, CA. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.tim2013-b97.

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Zhang, Manlin, Zhihui Liu, and Zhuo Yang. "EV483/#526 Restriction of YWHAB-mediated YAP cytoplasmic retention is a novel mechanism underlying stemness maintenanceand chemo-resistance in peritoneal metastasis of ovarian cancer revealed by comparative proteomic study." In IGCS 2024 Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2024. https://doi.org/10.1136/ijgc-2024-igcs.471.

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