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1

E., Kosh-Komba, Aba Toumnou L., Zinga I., and Touckia I. "Phytochemical Screening, Antifungal and Antibacterial Effect of Zanthoxylum zanthoxyloides and Zanthoxylum macrophylum Used in Traditional Medicine in Yamboro (Central African Republic)." European Journal of Medicinal Plants 19, no. 3 (2017): 1–11. https://doi.org/10.9734/EJMP/2017/33304.

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The knowledge of traditional medicine has always guided the search for new cures. <em>Zanthoxylum zanthoxyloides</em> and <em>Zanthoxylum macrophylum</em>, (Rutaceae) are used as medicinal plants in Central African Republic for bacteria and fungi treatment<strong>. </strong>The aim of this study is to investigate <em>in vitro</em> antibacterial and antifungal activities of water-alcohol extract of leave, bark and root of <em>Z. zanthoxyloides</em> and <em>Z. macrophylum </em>and the phytochemistry group of some secondary metabolic<em>.</em> The results of analysis of variance on the antibacter
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Kafuyemon Ismanth, Djaboutou, Lauris Fah, Phenix Assogba, et al. "COMPARATIVE STUDY OF THE ANTIBACTERIAL ACTIVITY OF ROOTS, BARKS AND LEAVES OF JATROPHA MULTIFIDA, JATROPHA CURCAS AND ZANTHOXYLUM ZANTHOXYLOIDES." International Journal of Advanced Research 12, no. 12 (2024): 409–18. https://doi.org/10.21474/ijar01/20038.

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Antimicrobial resistance is a major public health issue. This study compares the antibacterial activity of leaves, bark, and roots of Jatropha curcas, Jatropha multifida, and Zanthoxylum zanthoxyloides. Extracts (water, ethanolic, and hydro-ethanolic) were tested against Staphylococcus aureus and Klebsiella pneumoniae, and their antioxidant activity was assessed using the DPPH test. Polyphenol and flavonoid levels were quantified spectrophotometrically.Hydro-ethanolic extracts of J. multifida bark and Z. zanthoxyloides leaves showed strong activity against K. pneumoniae (MIC, MBC: 6.25mg for J
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Mano, Elias, Nadjatou Ouédraogo, Rabièta Simdé, et al. "Toxicity and Synergistic Effect of Native Plants Extracts against the Cowpea Weevil (Callosobruchus maculatus Fab.) (Coleoptera: Bruchidae)." Journal of Experimental Agriculture International 46, no. 9 (2024): 257–65. http://dx.doi.org/10.9734/jeai/2024/v46i92823.

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Callosobruchus maculatus causes loss of cowpea seeds and its weight after six months of unprotected storage. This study aimed to evaluate the toxicity and synergistic effects of plant extracts on the biological parameters of C. maculatus from Bobo Dioulasso in order to reduce its damage on cowpea stocks in Bobo Dioulasso city. Seven treatments including an untreated control and doses of three powdery extracts of Cassia nigricans, Zanthoxylum zanthoxyloides and Hyptis suaveolens, and their combinations were compared in a Fischer block with four completely randomized repetitions. One hundred hea
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Adewoye, Bolajoko B., and Emmanuela O. Ozodinobi. "Chemical Characterization and Entomotoxicity of the Powders and Oil Extracts of Zanthoxylum zanthoxyloides (Lam.) and Anarcadium occidentale (L.) on Sitophilus oryzae (L.)." Nigerian Journal of Entomology 40, no. 2 (2024): 227–41. http://dx.doi.org/10.36108/nje/4202/04.0281.

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The rice weevil, Sitophilus oryzae is a cosmopolitan and economic pest of stored rice and other cereals. This study assessed the phytochemical composition and entomotoxic effect of powders and ethanolic oil extracts of Zanthoxylum zanthoxyloides and Anacardium occidentale on S. oryzae. Phytochemical screening and Gas chromatography/mass spectrometry (GC-MS) analysis were carried out on the oils of Z. zanthoxyloides and A. occidentale, while powders and oils of both plants were further assessed for their toxicity to S. oryzae at 1.0 g, 1.5 g, 2.0 g and 0.0625 ml, 0.125 ml, 0.50ml concentrations
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Dofuor, Aboagye Kwarteng, Georgina Isabella Djameh, Frederick Ayertey, et al. "Antitrypanosomal Effects of Zanthoxylum zanthoxyloides (Lam.) Zepern. & Timler Extracts on African Trypanosomes." Evidence-Based Complementary and Alternative Medicine 2019 (July 4, 2019): 1–14. http://dx.doi.org/10.1155/2019/1730452.

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African trypanosomiasis is a disease caused by the parasitic protozoa of the Trypanosoma genus. Despite several efforts at chemotherapeutic interventions, the disease poses serious health and economic concerns to humans and livestock of many sub-Saharan African countries. Zanthoxylum zanthoxyloides (Lam.) Zepern. &amp; Timler (Z. zanthoxyloides LZT) is a plant species of important phytochemical and pharmacological relevance in the subtropical zones of the African continent. However, the mechanisms of its antitrypanosomal effects in African trypanosomes remain to be elucidated. The aim of the s
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Tougoma, Atèhèzi, Komi S. Atchrimi, Adama Dénou, Oto-Obong V. Idah, Gideon U. Egesie, and Samuel O. Odeh. "Antinociceptive evaluation of the aqueous bark extract of Zanthoxylum zanthoxyloides (Lam.) Zepern. and Timler (Rutaceae) on albino wistar rats." Journal of Applied Biosciences 160 (April 30, 2021): 16495–506. http://dx.doi.org/10.35759/jabs.160.6.

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Objectives: This study aimed to investigate the phytochemistry and the analgesic activity of the aqueous bark extract of Zanthoxylum zanthoxyloides (AZZ) on albino Wistar rats. Methodology and Results: Phytochemical screening was done using colorimetric reactions and precipitations. Writhing, glutamate, and hot plate tests were used for antinociceptive assessment. The animals were given the extract (400 and 800 mg/kg) and standard drugs, orally. The phytochemical screening has revealed chemical components like alkaloids and flavonoids. The extract displayed significant antinociceptive activity
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7

Togola Issiaka, N’Diaye Maïmounatou, Traoré Nah, Konaré Mamadou Abdoulaye, and Diarra Nouhoum. "Ethnobotanical and comparative study of the antioxidant and anti-inflammatory potential of three organs of Zanthoxylum zanthoxyloides, a plant used in the traditional treatment of sickle-cell disease in Bamako." GSC Biological and Pharmaceutical Sciences 25, no. 1 (2023): 019–30. http://dx.doi.org/10.30574/gscbps.2023.25.1.0402.

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The literature reports that the sickle cell patients frequently use plants to manage their recurrent attacks. The aim of the present study was to contribute to a better understanding of the medicinal plants used in the management of that disease. An ethnobotanical survey was conducted in and around Bamako. The most frequently cited species was selected: Zanthoxylum zanthoxyloides Lam. Zepernick. &amp; Timler, and the in vitro antioxidant and anti-inflammatory potential of their leaf, fruit and root extracts were assessed. A total of 39 people were surveyed, including 21 herbalists, 6 tradition
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Ampomah, Paulina, Wisdom Xoese Kwadzo Agroh, Ernest Amponsah Asiamah, and Sandra Nimakoh. "Zanthoxylum zanthoxyloides leaf extracts demonstrate antimicrobial effect on selected oral pathogens." Journal of Phytopharmacology 14, no. 1 (2025): 42–49. https://doi.org/10.31254/phyto.2025.14106.

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Background: Oral infections continue to be a major health problem and may be associated with conditions such as colorectal cancer, gum bleeding, toothache, preterm birth among pregnant mothers, arterial hardening, myocardial infarction and stroke. Yet available conventional treatments for oral infections are not only expensive and sometimes harmful but also ineffective compared to cheap and readily available plant-based ethnodentistry therapies because of increased resistance by microorganisms. This has necessitated the need to explore plant-based medicine for the purposes of controlling oral
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9

Danjuma, S., I. Muhammed, and G. Yahaya. "Evaluation of the Efficacy of Plant Materials for the Control of Flea Beetles Podagrica spp on Okra Abelmoschus esculentus L." Journal of Applied Sciences and Environmental Management 25, no. 4 (2021): 529–35. http://dx.doi.org/10.4314/jasem.v25i4.6.

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The efficacy of the Senegal prickly-ash Zanthoxylum zanthoxyloides (Lam.) roots and the African locust bean tree Parkia biglobosa (Jacq.) pod back was study for their efficacy in the control of okra pest, Podagrica spp. The study was carried out in the laboratory and on the field in the farming season of 2018. Z. zanthoxyloides roots were obtained from Jima-Doko forest and P. biglibosa fruit back from Takunpara. Both plant materials were air-dried under shade for 120 hours. Both plant parts were pounded separately in wooden mortar with the aid of wooden pestle until the materials turns to fine
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Togola, Issiaka, Maïmounatou N'Diaye, Nah Traoré, Mamadou Abdoulaye Konaré, and Nouhoum Diarra. "Ethnobotanical and comparative study of the antioxidant and anti-inflammatory potential of three organs of Zanthoxylum zanthoxyloides, a plant used in the traditional treatment of sickle-cell disease in Bamako." GSC Biological and Pharmaceutical Sciences 25, no. 1 (2023): 019–30. https://doi.org/10.5281/zenodo.10574585.

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The literature reports that the sickle cell patients frequently use plants to manage their recurrent attacks. The aim of the present study was to contribute to a better understanding of the medicinal plants used in the management of that disease. An ethnobotanical survey was conducted in and around Bamako. The most frequently cited species was selected:&nbsp;<em>Zanthoxylum zanthoxyloides&nbsp;</em>Lam. Zepernick. &amp; Timler, and the&nbsp;<em>in vitro</em>&nbsp;antioxidant and anti-inflammatory potential of their leaf, fruit and root extracts were assessed. A total of 39 people were surveyed
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Matthew Adinoyi, Augustine, Ofuya Thomas Inomisan, Idoko, Joy Ejemen, and Adesina Jacobs Mobolade. "RESPONSE OF FIVE SELECTED STORED LEGUME SEEDS SPECIES TO OVIPOSITION DETERRENT, OVICIDAL AND GRAIN PROTECTANT ACTIVITIES OF SOME BOTANICALS AGAINST Callosobruchus Maculatus (FAB.) (Coleoptera: Chrysomelidae)." Malaysian Journal of Sustainable Agriculture 7, no. 1 (2023): 58–64. http://dx.doi.org/10.26480/mjsa.01.2023.58.64.

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Ten plant powders were tested at 2% on five legume seeds for their entomocidal effects against Callosobruchus maculatus. A completely randomized design (CRD) with five pairs of freshly emerged adult bruchids was used to treat 40g of disinfected legume seed types with 2g of the selected plant powders. An analysis of variance was performed on the data on the percentage of oviposition deterrence, hatchability, pest tolerance, and weight loss. Zanthoxylum zanthoxyloides (87.02%) P. guineense (77.36%) and E. aromatica (73%) significantly deterred oviposition. The maximum percentage egg hatched was
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Monon, Koné, Touré Daouda, Yéo Sounta Oumar, et al. "Phytochemical Screening and Antibacterial Activity of Cassia Sieberiana DC. (Fabaceae) and Zanthoxylum zanthoxyloides (Lam.) Zepernick et Timler (Rutaceae) Leaves Extracts on Escherichia Coli Involved in Urinary Tract Infections." Microbiology Research Journal International 34, no. 12 (2024): 261–70. https://doi.org/10.9734/mrji/2024/v34i121527.

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Aims: Cassia sieberiana and Zanthoxylum zanthoxyloides are plants identified during an ethnobotanical survey, to threat urinary tract infections. The aim of this study was to investigate the antibacterial activity of aqueous and hydroalcoholic extracts obtained from leaves of C. sieberiana and Z. zanthoxyloides. t. Methodology: Phytochemical compounds were identified using colorimetric and precipitation methods. The sensitivity of isolates to plant extracts and their level of resistance to conventional antibiotics were assessed by agar diffusion on Escherichia coli isolates from patients with
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EBABHI, Abosede M., Adedotun A. ADEKUNLE, and Yoma I. OGHENERHABOKE. "In-vitro Control of Oral Thrush Causal Organisms Using Medicinal Plants Extracts." Notulae Scientia Biologicae 11, no. 3 (2019): 376–82. http://dx.doi.org/10.15835/nsb11310443.

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Oral hygiene is important to the generality of the human healthcare system. For this, the antifungal activities of the aqueous and ethanol extracts of four medicinal plants of Jatropha curcas (stem), Eucaluptus golbulus (leaves), Vernonia amygdalina (stem) and Zanthoxylum zanthoxyloides (root) were carried out in vitro against three species of Candida associated with oral thrush namely C. albicans, C. glabrata, C. tropicalis using the disc diffusion agar assay. The zones of inhibition varied with the test organisms as well as the extracts. The ethanolic extract of Jatropha curcas showed the hi
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14

Hounzangbe-Adote, S., I. Fouraste, K. Moutairou, and H. Hoste. "In vitro effects of four tropical plants on the activity and development of the parasitic nematode, Trichostrongylus colubriformis." Journal of Helminthology 79, no. 1 (2005): 29–33. http://dx.doi.org/10.1079/joh2004265.

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AbstractThe in vitro effects of extracts of four tropical plants (Zanthoxylum zanthoxyloides, Newbouldia laevis, Morinda lucida and Carica papaya) on the egg, infective larvae and adult worms of Trichostrongylus colubriformis were screened for potential anthelmintic properties. Significant effects were observed with the four plants on T. colubriformis but they differed depending on the stage of the parasite. Extracts of each plant induced a dose-dependent inhibition of egg hatching. Using a larval inhibition migration test, the effects on the infective larvae were also detected with the four p
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15

AYOKA, Thecla O., and Charles O. NNADI. "Lesser-known leafy vegetables of Southeastern Nigeria (Vitex doniana and Zanthoxylum zanthoxyloides)." Notulae Scientia Biologicae 14, no. 2 (2022): 11777. http://dx.doi.org/10.55779/nsb14211177.

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Vitex doniana and Zanthoxylum zanthoxyloides are plants grown in the Southeastern part of Nigeria. They have been used traditionally as food and in medicine, also in teeth cleaning and as a mouth wash to reduce pain. The availability of these plants has sparked a surge in interest in knowledge about their supplements and contents, including nutrients, mineral components, and bioactive chemicals, which are critical for drug discovery and development. Compounds derived from them have been used as effective pharmaceuticals throughout human history. This review is aimed at providing a comprehensiv
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Gbate, Mohammed, Olufemi Michael Ashamo, and Akinwande Lawrence Kayode. "Biopesticidal Effect of Partitioned Extracts of Zanthoxylum zanthoxyloides (Lam.) Zepernick & Timler on Callosobruchus maculatus (Fab.)." Journal of Agricultural Studies 9, no. 3 (2021): 215. http://dx.doi.org/10.5296/jas.v9i3.18867.

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Botanicals have become the focus for discovery of novel bioinsecticides for protection of crops most especially because of their biodegradability, non-toxicity, target organism specificity and environmental friendliness. Partitioned extracts of Zanthoxylum zanthoxyloides were investigated for biopesticidal effect on Callosobruchus maculatus with aim of identifying the most active components and increase ease of handling when compared to bulk crude plant material used by farmers. Crude powder of rootbark of Z. zanthoxyloides was made as well as partitioned extracts using Kupchan partition extra
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Tine, Yoro, Yin Yang, Franck Renucci, Jean Costa, Alassane Wélé, and Julien Paolini. "LC-MS/MS Analysis of Flavonoid Compounds from Zanthoxylum zanthoxyloides Extracts and Their Antioxidant Activities." Natural Product Communications 12, no. 12 (2017): 1934578X1701201. http://dx.doi.org/10.1177/1934578x1701201213.

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Flavonoids are a large group of phenolic secondary metabolites having a wide range of biochemical and pharmacological effects. In this work, a targeted liquid chromatography (LC) coupled with tandem mass spectrometry (MS2) was used to characterize the flavonoid compositions of methanolic plant extracts from separated parts (fruits, leaves, stems, trunk barks, and root barks) of Zanthoxylum zanthoxyloides. Nine flavonoids were reported in this species, including three flavanones, five flavonols and one flavone. Quantitative analysis of flavonoid profiles from Z. zanthoxyloides extracts is usefu
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Traore, Sylvain Gnamien, Vessaly Kallo, Alain Azokou, et al. "Efficacy of neem oil, <i>Zanthoxylum zanthoxyloides</i> and <i>Vernomia colorata</i> extracts on ticks and multi-resistant bacteria isolated from milk in the dairy value chain in Northern Côte d’Ivoire." International Journal of Biological and Chemical Sciences 17, no. 7 (2024): 2822–36. http://dx.doi.org/10.4314/ijbcs.v17i7.18.

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Livestock diseases are a major constraint to farmers in sub-Saharan Africa. However, an inadequate use of acaracides and antibiotics for animal diseases control leads to multi-resistance. Research on medicinal plants can be an alternative. The aim of this study was to assess the efficacy of three plant extracts on cattle ticks and multi-resistant bacteria isolated in milk from the Korhogo dairy basin. A cross- sectional survey was conducted from March to August 2023 in 24 farms in northern Côte d’Ivoire. Rhipicephalus (Boophilus) microplus and Amblyomma variegatum female adult ticks were sampl
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Dofuor, Kwain, Osei, et al. "N-(Isobutyl)-3,4-methylenedioxy Cinnamoyl Amide." Molbank 2019, no. 3 (2019): M1070. http://dx.doi.org/10.3390/m1070.

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The plant Zanthoxylum zanthoxyloides (Lam.) Zepern. &amp; Timler is one of the most important medicinal species of the genus Zanthoxylum on the African continent. It is used in the treatment and management of parasitic diseases in sub-Saharan Africa. These properties have inspired scientists to investigate species within the genus for bioactive compounds. However, a study, which details a spectroscopic, spectrometric and bioactivity guided extraction and isolation of antiparasitic compounds from the genus Zanthoxylum is currently non-existent. Tortozanthoxylamide (1), which is a derivative of
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Ikumawoyi, V. O., O. Awodele, K. Rotimi, and Y. A. Fashina. "EVALUATION OF THE EFFECTS OF THE HYDRO-ETHANOLIC ROOT EXTRACT OF ZANTHOXYLUM ZANTHOXYLOIDES ON HEMATOLOGICAL PARAMETERS AND OXIDATIVE STRESS IN CYCLOPHOSPAMIDE TREATED RATS." African Journal of Traditional, Complementary and Alternative Medicines 13, no. 5 (2016): 153–59. http://dx.doi.org/10.21010/ajtcam.v13i5.20.

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Background: The use of cyclophosphamide in cancer therapy is usually associated with challenging immunosuppression which exposes patients to increased risk of anemia and necessitating preventive measures during therapy. This study was carried out to investigate the efficacy of the hydro-ethanolic extract of the root of Z. zanthoxyloides in preventing and/or improving cyclophosphamide induced myelosuppression and oxidative stress in rats. Materials and Methods: Animals were divided into 6 groups of 6 rats each and were pretreated oral doses of 75, 150 and 225 mg/kg of the extract for 7 days and
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Cisse, Salimatou, Aime Ainin Somboro, Mamadou Badiaga, Niaboula Dembele, Nah Traore, and Pierre Chalard. "PHYTOCHIMIE E.T ACTIVITE ANTALGIQUE DE ZANTHOXYLUM ZANTHOXYLOIDES (LAM.) WATERMAN (RUTACEAE) RECOLTE AU MALI." International Journal of Advanced Research 12, no. 06 (2024): 1419–25. http://dx.doi.org/10.21474/ijar01/19005.

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Zanthoxylum zanthoxyloidesest une plantemedicinale de la famille des Rutaceae, largement utilisee en medecinetraditionnelle au Mali dans le traitement de nombreuses maladies dont la douleur.Lobjectif de letudeetaitdevaluerlactiviteantalgique des extraits (methanolique, acetate dethyle, butanolique et aqueux)des feuilles, tiges et racines de cette plante. Les constituants chimiques ont ete caracterises par les reactions en tube. Lactiviteantalgique des extraits a ete evaluee en utilisant le test de contorsion a travers la douleurinduite par lacideacetique chez des souris. Le screening phytochim
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Ferdinand, Guendehou, Djossa Agossou Bruno, Bio Anselme, and Assogbadjo Achille Ephrem. "Evaluation of the Fixed Population of Zanthoxylum zanthoxyloides (lam.) Zepernick & Timler Along the Climate Variation in Benin (West Africa)." Asian Plant Research Journal 13, no. 1 (2025): 69–80. https://doi.org/10.9734/aprj/2025/v13i1294.

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Z. zanthoxyloïdes is a versatile plant that serves multiple purposes. Consequently, it faces significant user demand in Benin. The present investigation evaluated the abundance of this species and conducted an ecological analysis of the existing habitats that sustain its growth. The inventory of Z. zanthoxyloïdes was carried out in 120 square 50 m x 50 m plots on mega-transets in the Lama, Wari-Maro and N'Dali classified forests and fallows that surround them. The results show that adult individuals are almost absent in fallow land and are found in natural forests (P&lt; 0.05). As for juvenile
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Ferreira, Rita de Cassia Alves de Brito, Cícero dos Santos Leandro, Francisco Bernardo de Barros, and Francisco Roberto de Azevedo. "Óleos essenciais no controle de carunchos (coleoptera: chrysomelidae: bruchinae) do feijão armazenado: uma revisão bibliográfica." Revista Ibero-Americana de Ciências Ambientais 12, no. 7 (2021): 448–64. http://dx.doi.org/10.6008/cbpc2179-6858.2021.007.0039.

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O Brasil é um grande produtor de grãos, sendo assim, é imprescindível o conhecimento de alternativas sustentáveis para o controle de pragas nos grãos armazenados, que são responsáveis por severas perdas. Este estudo de revisão objetivou reunir informações atualizadas sobre a atividade inseticida de óleos essenciais de plantas no controle de carunchos do feijão armazenado. Trata-se de um estudo descritivo e bibliográfico, com abordagem qualitativa. A coleta de dados foi realizada a partir das bases eletrônicas, Google acadêmico e o Portal de Periódicos da CAPES. As palavras-chave pesquisadas fo
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Ekwemba, C. O., N. Nwachukwu, and C. O. Ibegbulem. "Ethyl Acetate Fraction of Total Phenols from Zanthoxylum zanthoxyloides Leaves Treated Alloxan-Induced Diabetic Albino Rats." International Journal of Biochemistry Research & Review, October 21, 2021, 19–30. http://dx.doi.org/10.9734/ijbcrr/2021/v30i630273.

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Aims: Ethyl acetate fraction of total phenols from Zanthoxylum zanthoxyloides leaves was evaluated for its effects in alloxan-induced diabetic male albino rats.&#x0D; Methodology: Diabetes was induced in rats by administrating alloxan monohydrate at a dose of 130 mg/kg body weight. The ethyl acetate fraction was administered to rats at 100, 200 and 400 mg/kg b.w. daily for 15 days. Blood glucose, lipid profile and pancreatic histopathology were monitored using standard methods.&#x0D; Results: Results indicated that two weeks after treatment with Z. zanthoxyloides, significant (p&lt;0.05) reduc
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Ozigis, H. O., K. A. Olaifa, A. O. Agbeja, L. O. Asabia, D. R. Akindolu, and M. O. Majolagbe. "QUALITATIVE PHYTOCHEMICAL ANALYSIS OF LEAVE AND STEM BARK OF Zanthoxylum zanthoxyloides AND Zanthoxylum gilletti." Journal of Chemical Society of Nigeria 48, no. 3 (2023). http://dx.doi.org/10.46602/jcsn.v48i3.891.

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This study reveals result on qualitative phytochemical analysis, mineral analysis on powdered leaves and stem bark of Zanthoxylum zanthoxyloides and Zanthoxylum gilletti, micromorphology of the leaves of Zanthoxylum zanthoxyloides and Zanthoxylum gilletti. The phytochemicals analysis of the two species showed significant phytocompounds such as (saponnin, tannin,alkaloid, steroids, anthraquinone, cardiac glycosides and flavonoids) at varying strength of availability in the powdered leaves and stem bark. The leaves of Zanthoxylum zanthoxyloides were found to contains tannin, terpenoids, steroids
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James, Ayorinde Babatunde, Gbemisola Morounke Saibu, Olubunmi Abiola Magbagbeola, Sunday Aremu Omilabu, and Mervin Meyer. "Search for New Pro‐apoptotic agents in Indigenous Antitumor Plants in Nigeria." FASEB Journal 30, S1 (2016). http://dx.doi.org/10.1096/fasebj.30.1_supplement.612.11.

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Due to severe cytotoxicities exacerbated by cytotoxic drugs, newer therapies from natural products are desirable. This work aimed to partially purify pro‐apoptotic agents from indigenous natural products and to investigate the mechanism of action of the selected plant fractions.Sixteen indigenous medicinal plants were collected and fractionated into hexane (HF), chloroform (CF), ethylacetate (EAF), methanol (MF) and water (WF) fractions using solvent‐solvent partitioning and polyamide adsorption chromatography. The resultant ninety‐six test fractions were screened for lethality potential using
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Rukayyah, Sulaiman S., Jigam, Audu Ali, Abubakar Abdulkadir, and Salau, Rasaq Bolakale. "Crude Ethanolic Stem Bark Extract of Zanthoxylum zanthoxyloides and Its Fractions: In-Vitro and In-Vivo Antiplasmodial Activity." Nigerian Journal of Pure and Applied Sciences, December 4, 2021, 4153–63. http://dx.doi.org/10.48198/njpas/21.b03.

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Malaria is a global problem, as treatment failure has hampered the efficacy of most anti-malarial medications. The goal of this study was to see if stem bark extract from Zanthoxylum zanthoxyloides had antiplasmodial properties that could be used to treat both susceptible and resistant parasites. The stem bark of Z. zanthoxyloides (500g) was crushed and extracted with ethanol. The extract was tested for antiplasmodial activity in vitro against the chloroquine-sensitive (CQS) strain NF54 and chloroquine-resistant strains (CQR) K1 of P. falciparum, as well as in vivo against the CQS(NK65) strain
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Ouedraogo, Vincent, Eli Compaoré, Ablassé Rouamba, Moussa Compaoré, and Martin Kiendrebeogo. "Anti-virulence Activity of Three Medicinal Plants: Cassia occidentalis L., Crossopteryx febrifuga (Afzel ex G. Don) Benth. and Zanthoxylum zanthoxyloides (Lam) Zep. and Timl." Microbiology Research Journal International, October 3, 2019, 1–7. http://dx.doi.org/10.9734/mrji/2019/v29i130152.

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Aims: This current study was designated to assess the ability of Cassia occidentalis, Crossopteryx febrifuga and Zanthoxylum zanthoxyloides traditionally used for the treatment of infectious diseases, to reduce the production of virulence factors.&#x0D; Place and Duration of Study: The study was conducted at the Laboratory of Applied Biochemistry and Chemistry (LABIOCA), University Ouaga 1 Pr Joseph KI-ZERBO between September 2018 to January 2019.&#x0D; Methodology: Methanol extracts from C. occidentalis (leaves and stem), C. febrifuga (leaves and stem) and Z. zanthoxyloides (Stem bark) were u
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Correa-Barbosa, Juliana, Daniele Ferreira Sodré, Pedro Henrique Costa Nascimento, and Maria Fâni Dolabela. "Activity of the genus Zanthoxylum against diseases caused by protozoa: A systematic review." Frontiers in Pharmacology 13 (January 9, 2023). http://dx.doi.org/10.3389/fphar.2022.873208.

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Neglected diseases (NDs) are treated with a less varied range of drugs, with high cost and toxicity, which makes the search for therapeutic alternatives important. In this context, plants, such as those from the genus Zanthoxylum, can be promising due to active substances in their composition. This study evaluates the potential of species from this genus to treat NDs. Initially, a protocol was developed to carry out a systematic review approved by Prospero (CRD42020200438). The databases PubMed, BVS, Scopus, Science Direct, and Web of Science were used with the following keywords: “zanthoxylum
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DAS, MOULI. "MOLECULAR DOCKING STUDY: TARGETING SICKLE CELL ANEMIA USING ACTIVE PHYTOCHEMICAL COMPOUNDS FROM ZANTHOXYLUM ZANTHOXYLOIDES." Innovare Journal of Medical Sciences, May 1, 2023, 14–18. http://dx.doi.org/10.22159/ijms.2023.v11i3.47983.

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Objectives: A category of genetic disease which is sickle cell disease is called sickle cell anemia. In this, the red blood cells are affected in shape and structure, which normally carries oxygen to every part of our body. Therefore, by using molecular docking studies, Absorption, Distribution, Metabolism, and Excretion (ADME) analysis for phytocompounds, an effort was made to find natural compounds from a plant named Zanthoxylum zanthoxyloides, which has many medicinal properties in Indian Ayurveda, to prevent this genetic disease. Methods: The Protein Data Bank database was used to retrieve
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Ayoka, Thecla Okeahunwa, Ngwu Nwachukwu, Aloysius Chinedu Ene, Chidi Uzoma Igwe, and Charles Okeke Nnadi. "The Hepatocurative Effects of Zanthoxylum zanthoxyloides Alkaloids on Tetrachloromethane-Induced Hepatotoxicity on Albino Rats." Indian Journal of Clinical Biochemistry, November 12, 2022. http://dx.doi.org/10.1007/s12291-022-01095-z.

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