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1

Kafuyemon Ismanth, Djaboutou, Lauris Fah, Phenix Assogba, et al. "COMPARATIVE STUDY OF THE ANTIBACTERIAL ACTIVITY OF ROOTS, BARKS AND LEAVES OF JATROPHA MULTIFIDA, JATROPHA CURCAS AND ZANTHOXYLUM ZANTHOXYLOIDES." International Journal of Advanced Research 12, no. 12 (2024): 409–18. https://doi.org/10.21474/ijar01/20038.

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Antimicrobial resistance is a major public health issue. This study compares the antibacterial activity of leaves, bark, and roots of Jatropha curcas, Jatropha multifida, and Zanthoxylum zanthoxyloides. Extracts (water, ethanolic, and hydro-ethanolic) were tested against Staphylococcus aureus and Klebsiella pneumoniae, and their antioxidant activity was assessed using the DPPH test. Polyphenol and flavonoid levels were quantified spectrophotometrically.Hydro-ethanolic extracts of J. multifida bark and Z. zanthoxyloides leaves showed strong activity against K. pneumoniae (MIC, MBC: 6.25mg for J
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E., Kosh-Komba, Aba Toumnou L., Zinga I., and Touckia I. "Phytochemical Screening, Antifungal and Antibacterial Effect of Zanthoxylum zanthoxyloides and Zanthoxylum macrophylum Used in Traditional Medicine in Yamboro (Central African Republic)." European Journal of Medicinal Plants 19, no. 3 (2017): 1–11. https://doi.org/10.9734/EJMP/2017/33304.

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The knowledge of traditional medicine has always guided the search for new cures. <em>Zanthoxylum zanthoxyloides</em> and <em>Zanthoxylum macrophylum</em>, (Rutaceae) are used as medicinal plants in Central African Republic for bacteria and fungi treatment<strong>. </strong>The aim of this study is to investigate <em>in vitro</em> antibacterial and antifungal activities of water-alcohol extract of leave, bark and root of <em>Z. zanthoxyloides</em> and <em>Z. macrophylum </em>and the phytochemistry group of some secondary metabolic<em>.</em> The results of analysis of variance on the antibacter
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3

Enechi, Osmund Chukwuma Okeke Emmanuel Sunday* Abonyi Uchenna Collins Nwankwo Nicodemus Emeka Ndimele Ugochi Joy Benneth Moses Ebere. "EVALUATION OF IN VITRO ANTI-INFLAMMATORY AND ANTIOXIDANT POTENTIALS OF METHANOL LEAF EXTRACT OF FAGARA ZANTHOXYLOIDES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 08 (2019): 14365–71. https://doi.org/10.5281/zenodo.3360753.

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<strong><em>Background:</em></strong><em> Fagara zanthoxyloides is a medicinal plant used in traditional medicine for the treatment of elephantiasis, toothache, sexual impotence, malaria, dysmenorrheal and abdominal pain among rural dwellers.</em> <strong><em>Objective:</em></strong><em> To study the In vitro anti-inflammatory and antioxidant activities of methanol extract of Fagara zanthoxyloides leaves.</em> <strong><em>Materials and Methods:</em></strong><em> Methanol extract of Fagara zanthoxyloides leaves were used for this study. In vitro anti-inflammatory studies were performed for the
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Mano, Elias, Nadjatou Ouédraogo, Rabièta Simdé, et al. "Toxicity and Synergistic Effect of Native Plants Extracts against the Cowpea Weevil (Callosobruchus maculatus Fab.) (Coleoptera: Bruchidae)." Journal of Experimental Agriculture International 46, no. 9 (2024): 257–65. http://dx.doi.org/10.9734/jeai/2024/v46i92823.

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Callosobruchus maculatus causes loss of cowpea seeds and its weight after six months of unprotected storage. This study aimed to evaluate the toxicity and synergistic effects of plant extracts on the biological parameters of C. maculatus from Bobo Dioulasso in order to reduce its damage on cowpea stocks in Bobo Dioulasso city. Seven treatments including an untreated control and doses of three powdery extracts of Cassia nigricans, Zanthoxylum zanthoxyloides and Hyptis suaveolens, and their combinations were compared in a Fischer block with four completely randomized repetitions. One hundred hea
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Adewoye, Bolajoko B., and Emmanuela O. Ozodinobi. "Chemical Characterization and Entomotoxicity of the Powders and Oil Extracts of Zanthoxylum zanthoxyloides (Lam.) and Anarcadium occidentale (L.) on Sitophilus oryzae (L.)." Nigerian Journal of Entomology 40, no. 2 (2024): 227–41. http://dx.doi.org/10.36108/nje/4202/04.0281.

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The rice weevil, Sitophilus oryzae is a cosmopolitan and economic pest of stored rice and other cereals. This study assessed the phytochemical composition and entomotoxic effect of powders and ethanolic oil extracts of Zanthoxylum zanthoxyloides and Anacardium occidentale on S. oryzae. Phytochemical screening and Gas chromatography/mass spectrometry (GC-MS) analysis were carried out on the oils of Z. zanthoxyloides and A. occidentale, while powders and oils of both plants were further assessed for their toxicity to S. oryzae at 1.0 g, 1.5 g, 2.0 g and 0.0625 ml, 0.125 ml, 0.50ml concentrations
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6

Tougoma, Atèhèzi, Komi S. Atchrimi, Adama Dénou, Oto-Obong V. Idah, Gideon U. Egesie, and Samuel O. Odeh. "Antinociceptive evaluation of the aqueous bark extract of Zanthoxylum zanthoxyloides (Lam.) Zepern. and Timler (Rutaceae) on albino wistar rats." Journal of Applied Biosciences 160 (April 30, 2021): 16495–506. http://dx.doi.org/10.35759/jabs.160.6.

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Objectives: This study aimed to investigate the phytochemistry and the analgesic activity of the aqueous bark extract of Zanthoxylum zanthoxyloides (AZZ) on albino Wistar rats. Methodology and Results: Phytochemical screening was done using colorimetric reactions and precipitations. Writhing, glutamate, and hot plate tests were used for antinociceptive assessment. The animals were given the extract (400 and 800 mg/kg) and standard drugs, orally. The phytochemical screening has revealed chemical components like alkaloids and flavonoids. The extract displayed significant antinociceptive activity
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7

Dofuor, Aboagye Kwarteng, Georgina Isabella Djameh, Frederick Ayertey, et al. "Antitrypanosomal Effects of Zanthoxylum zanthoxyloides (Lam.) Zepern. & Timler Extracts on African Trypanosomes." Evidence-Based Complementary and Alternative Medicine 2019 (July 4, 2019): 1–14. http://dx.doi.org/10.1155/2019/1730452.

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African trypanosomiasis is a disease caused by the parasitic protozoa of the Trypanosoma genus. Despite several efforts at chemotherapeutic interventions, the disease poses serious health and economic concerns to humans and livestock of many sub-Saharan African countries. Zanthoxylum zanthoxyloides (Lam.) Zepern. &amp; Timler (Z. zanthoxyloides LZT) is a plant species of important phytochemical and pharmacological relevance in the subtropical zones of the African continent. However, the mechanisms of its antitrypanosomal effects in African trypanosomes remain to be elucidated. The aim of the s
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8

Goodman, Christopher Dean, An Thuy Hoang, Drissa Diallo, Karl Egil Malterud, Geoffrey I. McFadden, and Helle Wangensteen. "Anti-plasmodial Effects of Zanthoxylum zanthoxyloides." Planta Medica 85, no. 13 (2019): 1073–79. http://dx.doi.org/10.1055/a-0973-0067.

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Abstract Zanthoxylum zanthoxyloides, syn. Fagara zanthoxyloides, is a tree growing in West Africa and is used in traditional medicine against a variety of diseases, including malaria. In the work reported here, root bark and stem bark extracts of this tree, as well as compounds isolated from the extracts, have been investigated for activity in vitro against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum. In addition, toxicity against nauplii of the brine shrimp Artemia salina has been studied. Dichloromethane extracts of the root bark and stem bark, and a meth
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Tiga, Neya, Daboue Edhit, Neya Oble, and Ouedraogo Issaka. "Germination Characteristics of Parinari curatellifolia Planch. Ex Benth, Vitex doniana Sweet and Zanthoxylum zanthoxyloides (Lam) Watermann Seeds." Annual Research & Review in Biology 12, no. 3 (2017): 1–12. https://doi.org/10.9734/ARRB/2017/32209.

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Germination characteristics studies of seeds of three local species in Burkina Faso namely <em>Parinari curatellifolia, Vitex doniana </em>and<em> Zanthoxylum zanthoxyloides</em> have been carried out. The aim of this study was to carry out the appropriate pre-treatment and temperature which give the best percentage of seed germination for these three locales species. For that the seed were placed in different temperature 15°C; 20°C; 25°C; 30°C; 35°C and 19 pre-treatment from Soaking in water x hours; Scalding, Cooking x minute, Soaking of sulfuric acid x minute, scarification and decorticatin
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AYOKA, Thecla O., and Charles O. NNADI. "Lesser-known leafy vegetables of Southeastern Nigeria (Vitex doniana and Zanthoxylum zanthoxyloides)." Notulae Scientia Biologicae 14, no. 2 (2022): 11777. http://dx.doi.org/10.55779/nsb14211177.

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Vitex doniana and Zanthoxylum zanthoxyloides are plants grown in the Southeastern part of Nigeria. They have been used traditionally as food and in medicine, also in teeth cleaning and as a mouth wash to reduce pain. The availability of these plants has sparked a surge in interest in knowledge about their supplements and contents, including nutrients, mineral components, and bioactive chemicals, which are critical for drug discovery and development. Compounds derived from them have been used as effective pharmaceuticals throughout human history. This review is aimed at providing a comprehensiv
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11

Peter Abimbola, Oluyori, Inyinbor Abosede Adejumoke, Dada Adewumi Oluwasogo, Oyedepo Grace Olapeju, Abodunrin Temitope Olabisi, and Awolesi Oluwafemi. "Antioxidant Potential of Zingiber officinale Rhizome and Fagara zanthoxyloides Root Extracts and their Application in Soybean oil During Accelerated Storage." Oriental Journal of Chemistry 35, no. 2 (2019): 778–84. http://dx.doi.org/10.13005/ojc/350239.

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The oxidative instability of vegetable oils which contain polyunsaturated fatty acids and the health implication of synthetic antioxidants is the reason for the current intensive search for safer natural antioxidants. Hence, the total phenolic content and 2,2-diphenyl-1-picryhydrazyl (DPPH) radical scavenging activity of Fagara zanthoxyloides root and Zingiber officinale rhizome have been comparatively evaluated. Zingiber officinale cold extract (GC) exhibited highest DPPH scavenging activity as well as the highest TPC while the hot extract from Fagara zanthoxyloides root (FH) had more phenoli
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12

Togola Issiaka, N’Diaye Maïmounatou, Traoré Nah, Konaré Mamadou Abdoulaye, and Diarra Nouhoum. "Ethnobotanical and comparative study of the antioxidant and anti-inflammatory potential of three organs of Zanthoxylum zanthoxyloides, a plant used in the traditional treatment of sickle-cell disease in Bamako." GSC Biological and Pharmaceutical Sciences 25, no. 1 (2023): 019–30. http://dx.doi.org/10.30574/gscbps.2023.25.1.0402.

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The literature reports that the sickle cell patients frequently use plants to manage their recurrent attacks. The aim of the present study was to contribute to a better understanding of the medicinal plants used in the management of that disease. An ethnobotanical survey was conducted in and around Bamako. The most frequently cited species was selected: Zanthoxylum zanthoxyloides Lam. Zepernick. &amp; Timler, and the in vitro antioxidant and anti-inflammatory potential of their leaf, fruit and root extracts were assessed. A total of 39 people were surveyed, including 21 herbalists, 6 tradition
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13

Queiroz, Emerson, Anne-Emmanuelle Hay, Fatima Chaaib, Daphné van Diemen, Drissa Diallo, and Kurt Hostettmann. "New and Bioactive Aromatic Compounds fromZanthoxylum zanthoxyloides." Planta Medica 72, no. 08 (2006): 746–50. http://dx.doi.org/10.1055/s-2006-941504.

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14

Shittu, AO, A. Aliyu, MS David, NS Njinga, and HI Ishaq. "Potential Antibacterial Activity of Two Important Local Chewing Sticks “Fagara zanthoxyloides and Distemonanthus benthamianus” along with Antioxidant Capacities." Dhaka University Journal of Pharmaceutical Sciences 18, no. 2 (2019): 223–32. http://dx.doi.org/10.3329/dujps.v18i2.44462.

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In order to authenticate and ascertain the various claim by the rural dwellers that depend on chewing sticks for their oral hygiene and protection against innumerable diseases, the antibacterial activity of the roots of Fagara zanthoxyloides and Distemonanthus benthamianus were evaluated. Preliminary phytochemical screening was carried out using standard methods. In-vitro antibacterial activity of the methanol extracts of both plants was also carried out using the agar well diffusion method against standard strains of Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Escheri
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Ampomah, Paulina, Wisdom Xoese Kwadzo Agroh, Ernest Amponsah Asiamah, and Sandra Nimakoh. "Zanthoxylum zanthoxyloides leaf extracts demonstrate antimicrobial effect on selected oral pathogens." Journal of Phytopharmacology 14, no. 1 (2025): 42–49. https://doi.org/10.31254/phyto.2025.14106.

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Background: Oral infections continue to be a major health problem and may be associated with conditions such as colorectal cancer, gum bleeding, toothache, preterm birth among pregnant mothers, arterial hardening, myocardial infarction and stroke. Yet available conventional treatments for oral infections are not only expensive and sometimes harmful but also ineffective compared to cheap and readily available plant-based ethnodentistry therapies because of increased resistance by microorganisms. This has necessitated the need to explore plant-based medicine for the purposes of controlling oral
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Matthew Adinoyi, Augustine, Ofuya Thomas Inomisan, Idoko, Joy Ejemen, and Adesina Jacobs Mobolade. "RESPONSE OF FIVE SELECTED STORED LEGUME SEEDS SPECIES TO OVIPOSITION DETERRENT, OVICIDAL AND GRAIN PROTECTANT ACTIVITIES OF SOME BOTANICALS AGAINST Callosobruchus Maculatus (FAB.) (Coleoptera: Chrysomelidae)." Malaysian Journal of Sustainable Agriculture 7, no. 1 (2023): 58–64. http://dx.doi.org/10.26480/mjsa.01.2023.58.64.

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Ten plant powders were tested at 2% on five legume seeds for their entomocidal effects against Callosobruchus maculatus. A completely randomized design (CRD) with five pairs of freshly emerged adult bruchids was used to treat 40g of disinfected legume seed types with 2g of the selected plant powders. An analysis of variance was performed on the data on the percentage of oviposition deterrence, hatchability, pest tolerance, and weight loss. Zanthoxylum zanthoxyloides (87.02%) P. guineense (77.36%) and E. aromatica (73%) significantly deterred oviposition. The maximum percentage egg hatched was
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EBABHI, Abosede M., Adedotun A. ADEKUNLE, and Yoma I. OGHENERHABOKE. "In-vitro Control of Oral Thrush Causal Organisms Using Medicinal Plants Extracts." Notulae Scientia Biologicae 11, no. 3 (2019): 376–82. http://dx.doi.org/10.15835/nsb11310443.

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Oral hygiene is important to the generality of the human healthcare system. For this, the antifungal activities of the aqueous and ethanol extracts of four medicinal plants of Jatropha curcas (stem), Eucaluptus golbulus (leaves), Vernonia amygdalina (stem) and Zanthoxylum zanthoxyloides (root) were carried out in vitro against three species of Candida associated with oral thrush namely C. albicans, C. glabrata, C. tropicalis using the disc diffusion agar assay. The zones of inhibition varied with the test organisms as well as the extracts. The ethanolic extract of Jatropha curcas showed the hi
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Hounzangbe-Adote, S., I. Fouraste, K. Moutairou, and H. Hoste. "In vitro effects of four tropical plants on the activity and development of the parasitic nematode, Trichostrongylus colubriformis." Journal of Helminthology 79, no. 1 (2005): 29–33. http://dx.doi.org/10.1079/joh2004265.

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AbstractThe in vitro effects of extracts of four tropical plants (Zanthoxylum zanthoxyloides, Newbouldia laevis, Morinda lucida and Carica papaya) on the egg, infective larvae and adult worms of Trichostrongylus colubriformis were screened for potential anthelmintic properties. Significant effects were observed with the four plants on T. colubriformis but they differed depending on the stage of the parasite. Extracts of each plant induced a dose-dependent inhibition of egg hatching. Using a larval inhibition migration test, the effects on the infective larvae were also detected with the four p
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Danjuma, S., I. Muhammed, and G. Yahaya. "Evaluation of the Efficacy of Plant Materials for the Control of Flea Beetles Podagrica spp on Okra Abelmoschus esculentus L." Journal of Applied Sciences and Environmental Management 25, no. 4 (2021): 529–35. http://dx.doi.org/10.4314/jasem.v25i4.6.

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The efficacy of the Senegal prickly-ash Zanthoxylum zanthoxyloides (Lam.) roots and the African locust bean tree Parkia biglobosa (Jacq.) pod back was study for their efficacy in the control of okra pest, Podagrica spp. The study was carried out in the laboratory and on the field in the farming season of 2018. Z. zanthoxyloides roots were obtained from Jima-Doko forest and P. biglibosa fruit back from Takunpara. Both plant materials were air-dried under shade for 120 hours. Both plant parts were pounded separately in wooden mortar with the aid of wooden pestle until the materials turns to fine
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Togola, Issiaka, Maïmounatou N'Diaye, Nah Traoré, Mamadou Abdoulaye Konaré, and Nouhoum Diarra. "Ethnobotanical and comparative study of the antioxidant and anti-inflammatory potential of three organs of Zanthoxylum zanthoxyloides, a plant used in the traditional treatment of sickle-cell disease in Bamako." GSC Biological and Pharmaceutical Sciences 25, no. 1 (2023): 019–30. https://doi.org/10.5281/zenodo.10574585.

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The literature reports that the sickle cell patients frequently use plants to manage their recurrent attacks. The aim of the present study was to contribute to a better understanding of the medicinal plants used in the management of that disease. An ethnobotanical survey was conducted in and around Bamako. The most frequently cited species was selected:&nbsp;<em>Zanthoxylum zanthoxyloides&nbsp;</em>Lam. Zepernick. &amp; Timler, and the&nbsp;<em>in vitro</em>&nbsp;antioxidant and anti-inflammatory potential of their leaf, fruit and root extracts were assessed. A total of 39 people were surveyed
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Vyry Wouatsa, N. A., L. N. Misra, R. Venkatesh Kumar, Mahendra P. Darokar, and Francois Tchoumbougnang. "Zantholic acid, a new monoterpenoid from Zanthoxylum zanthoxyloides." Natural Product Research 27, no. 21 (2013): 1994–98. http://dx.doi.org/10.1080/14786419.2013.811662.

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Monon, Koné, Touré Daouda, Yéo Sounta Oumar, et al. "Phytochemical Screening and Antibacterial Activity of Cassia Sieberiana DC. (Fabaceae) and Zanthoxylum zanthoxyloides (Lam.) Zepernick et Timler (Rutaceae) Leaves Extracts on Escherichia Coli Involved in Urinary Tract Infections." Microbiology Research Journal International 34, no. 12 (2024): 261–70. https://doi.org/10.9734/mrji/2024/v34i121527.

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Aims: Cassia sieberiana and Zanthoxylum zanthoxyloides are plants identified during an ethnobotanical survey, to threat urinary tract infections. The aim of this study was to investigate the antibacterial activity of aqueous and hydroalcoholic extracts obtained from leaves of C. sieberiana and Z. zanthoxyloides. t. Methodology: Phytochemical compounds were identified using colorimetric and precipitation methods. The sensitivity of isolates to plant extracts and their level of resistance to conventional antibiotics were assessed by agar diffusion on Escherichia coli isolates from patients with
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Ouattara, Lassina. "Oilseeds Potential of Zanthoxylum zanthoxyloides (Lam.) Zepernick and Timler." International Journal of Pure & Applied Bioscience 4, no. 5 (2016): 23–28. http://dx.doi.org/10.18782/2320-7051.2394.

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Guetchueng, Stephanie T., Lutfun Nahar, Kenneth J. Ritchie, Fyaz M. D. Ismail, Andrew R. Evans, and Satyajit D. Sarker. "Zanthoamides G-I: Three new alkamides from Zanthoxylum zanthoxyloides." Phytochemistry Letters 26 (August 2018): 125–29. http://dx.doi.org/10.1016/j.phytol.2018.05.031.

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Adesina, S. K. "Further Novel Constituents of Zanthoxylum zanthoxyloides Root and Pericarp." Journal of Natural Products 49, no. 4 (1986): 715–16. http://dx.doi.org/10.1021/np50046a035.

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Gbate, Mohammed, Olufemi Michael Ashamo, and Akinwande Lawrence Kayode. "Biopesticidal Effect of Partitioned Extracts of Zanthoxylum zanthoxyloides (Lam.) Zepernick & Timler on Callosobruchus maculatus (Fab.)." Journal of Agricultural Studies 9, no. 3 (2021): 215. http://dx.doi.org/10.5296/jas.v9i3.18867.

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Botanicals have become the focus for discovery of novel bioinsecticides for protection of crops most especially because of their biodegradability, non-toxicity, target organism specificity and environmental friendliness. Partitioned extracts of Zanthoxylum zanthoxyloides were investigated for biopesticidal effect on Callosobruchus maculatus with aim of identifying the most active components and increase ease of handling when compared to bulk crude plant material used by farmers. Crude powder of rootbark of Z. zanthoxyloides was made as well as partitioned extracts using Kupchan partition extra
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Acheampong, Desmond Omane, Isaac Kyei Baffour, Victor Yao Atsu Barku, Justice Kwaku Addo, Mainprice Akuoko Essuman, and Alex Boye. "Zanthoxylum zanthoxyloides Alkaloidal Extract Improves CCl4-Induced Hepatocellular Carcinoma-Like Phenotypes in Rats." Evidence-Based Complementary and Alternative Medicine 2021 (July 21, 2021): 1–16. http://dx.doi.org/10.1155/2021/3804379.

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Background. Despite the enrollment of new small molecules such as Sorafenib for the treatment of hepatocellular carcinoma (HCC), HCC still remains a significant contributor to cancer-related mortality and morbidity globally. Zanthoxylum zanthoxyloides is long suspected of possessing anticancer bioactive compounds that may hold the prospect of adjunctive therapy against inflammation-related cancers such as HCC. Objective. This study assessed the effects of an alkaloidal extract of the leaves of Zanthoxylum zanthoxyloides on CCl4/olive oil (1 : 1 v/v)-induced HCC-like phenotypes in rats. Materia
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Tine, Yoro, Yin Yang, Franck Renucci, Jean Costa, Alassane Wélé, and Julien Paolini. "LC-MS/MS Analysis of Flavonoid Compounds from Zanthoxylum zanthoxyloides Extracts and Their Antioxidant Activities." Natural Product Communications 12, no. 12 (2017): 1934578X1701201. http://dx.doi.org/10.1177/1934578x1701201213.

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Flavonoids are a large group of phenolic secondary metabolites having a wide range of biochemical and pharmacological effects. In this work, a targeted liquid chromatography (LC) coupled with tandem mass spectrometry (MS2) was used to characterize the flavonoid compositions of methanolic plant extracts from separated parts (fruits, leaves, stems, trunk barks, and root barks) of Zanthoxylum zanthoxyloides. Nine flavonoids were reported in this species, including three flavanones, five flavonols and one flavone. Quantitative analysis of flavonoid profiles from Z. zanthoxyloides extracts is usefu
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Traore, Sylvain Gnamien, Vessaly Kallo, Alain Azokou, et al. "Efficacy of neem oil, <i>Zanthoxylum zanthoxyloides</i> and <i>Vernomia colorata</i> extracts on ticks and multi-resistant bacteria isolated from milk in the dairy value chain in Northern Côte d’Ivoire." International Journal of Biological and Chemical Sciences 17, no. 7 (2024): 2822–36. http://dx.doi.org/10.4314/ijbcs.v17i7.18.

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Livestock diseases are a major constraint to farmers in sub-Saharan Africa. However, an inadequate use of acaracides and antibiotics for animal diseases control leads to multi-resistance. Research on medicinal plants can be an alternative. The aim of this study was to assess the efficacy of three plant extracts on cattle ticks and multi-resistant bacteria isolated in milk from the Korhogo dairy basin. A cross- sectional survey was conducted from March to August 2023 in 24 farms in northern Côte d’Ivoire. Rhipicephalus (Boophilus) microplus and Amblyomma variegatum female adult ticks were sampl
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Chaaib, Fatima, Emerson F. Queiroz, Karine Ndjoko, Drissa Diallo, and Kurt Hostettmann. "Antifungal and Antioxidant Compounds from the Root Bark ofFagara zanthoxyloides." Planta Medica 69, no. 4 (2003): 316–20. http://dx.doi.org/10.1055/s-2003-38877.

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Dofuor, Kwain, Osei, et al. "N-(Isobutyl)-3,4-methylenedioxy Cinnamoyl Amide." Molbank 2019, no. 3 (2019): M1070. http://dx.doi.org/10.3390/m1070.

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The plant Zanthoxylum zanthoxyloides (Lam.) Zepern. &amp; Timler is one of the most important medicinal species of the genus Zanthoxylum on the African continent. It is used in the treatment and management of parasitic diseases in sub-Saharan Africa. These properties have inspired scientists to investigate species within the genus for bioactive compounds. However, a study, which details a spectroscopic, spectrometric and bioactivity guided extraction and isolation of antiparasitic compounds from the genus Zanthoxylum is currently non-existent. Tortozanthoxylamide (1), which is a derivative of
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Cissé, Salimatou, Aimé Anin Somboro, Mody Cissé, et al. "Contribution to the ethnobotanical and phytochemical study of Zanthoxylum zanthoxyloides (Lam.) Waterman (Rutaceae) from Mali." Journal of Drug Delivery and Therapeutics 12, no. 6 (2022): 10–15. http://dx.doi.org/10.22270/jddt.v12i6.5745.

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Zanthoxylum zanthoxyloides (Lam.) Waterman (Rutaceae) is a tree from 5 to 15 m high that grows spontaneously in West Africa. It is frequently used in Malian traditional medicine for the treatment of various ailments. Thus, the present work is part of the development of this plant through an ethnobotanical survey and a phytochemical study of its leaves, stems and roots collected in Yanfolila and Ouélessébougou. The ethnobotanical survey showed that this species is used in the treatment of various pathologies such as tooth decay, toothache, throat, stomach and headaches, sickle cell anemia, ster
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Kassim, Olakunle O., Mark Loyevsky, Biaffra Elliott, Andrew Geall, Henrietta Amonoo, and Victor R. Gordeuk. "Effects of Root Extracts of Fagara zanthoxyloides on the In Vitro Growth and Stage Distribution of Plasmodium falciparum." Antimicrobial Agents and Chemotherapy 49, no. 1 (2005): 264–68. http://dx.doi.org/10.1128/aac.49.1.264-268.2005.

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ABSTRACT The development of resistance by Plasmodium falciparum to conventional drugs poses a threat to malaria control. There is therefore a need to find new, effective, and affordable remedies for malaria, including those derived from plants. This study demonstrates that crude, reverse-phase high-pressure liquid chromatography (RP-HPLC)-semipurified, and RP-HPLC-purified root extracts of Fagara zanthoxyloides inhibit the growth of P. falciparum in vitro, with 50% inhibitory concentrations (IC50s) of 4.90, 1.00, and 0.13 μg/ml, respectively. Roots of F. zanthoxyloides, known as chewing sticks
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Ynalvez, R. A., C. Cardenas, J. K. Addo, G. E. Adukpo, B. A. Dadson, and A. Addo-Mensa. "Evaluation of the Antimicrobial Activity of Zanthoxylum zanthoxyloides Root Bark Extracts." Research Journal of Medicinal Plant 6, no. 2 (2012): 149–59. http://dx.doi.org/10.3923/rjmp.2012.149.159.

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Dofuor, Aboagye Kwarteng, Frederick Ayertey, Peter Bolah, et al. "Isolation and Antitrypanosomal Characterization of Furoquinoline and Oxylipin from Zanthoxylum zanthoxyloides." Biomolecules 10, no. 12 (2020): 1670. http://dx.doi.org/10.3390/biom10121670.

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In the absence of vaccines, there is a need for alternative sources of effective chemotherapy for African trypanosomiasis (AT). The increasing rate of resistance and toxicity of commercially available antitrypanosomal drugs also necessitates an investigation into the mode of action of new antitrypanosomals for AT. In this study, furoquinoline 4, 7, 8-trimethoxyfuro (2, 3-b) quinoline (compound 1) and oxylipin 9-oxo-10, 12-octadecadienoic acid (compound 2) were isolated from the plant species Zanthoxylum zanthoxyloides (Lam) Zepern and Timler (root), and their in vitro efficacy and mechanisms o
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Ouattara, B., O. Jansen, L. Angenot, et al. "Antisickling properties of divanilloylquinic acids isolated from Fagara zanthoxyloides Lam. (Rutaceae)." Phytomedicine 16, no. 2-3 (2009): 125–29. http://dx.doi.org/10.1016/j.phymed.2008.10.013.

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Ouédraogo, Lassané, Dominik Fuchs, Hanno Schaefer, and Martin Kiendrebeogo. "Morphological and Molecular Characterization of Zanthoxylum zanthoxyloides (Rutaceae) from Burkina Faso." Plants 8, no. 9 (2019): 353. http://dx.doi.org/10.3390/plants8090353.

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Zanthoxylum zanthoxyloides is a West African forest tree that is used for example against malaria and sickle cell anemia in Burkina Faso. The goal of this study was to analyze the genetic and morphological diversity of the species within wild populations in Burkina Faso, where it is potentially under threat due to the uncontrolled harvesting of its roots. Seventy-two trees from three different sites in Southwestern Burkina Faso were analyzed. Each tree was characterized by 12 traits specifying the period of flowering and maturity as well as morphological characteristics of the stem, leaves, an
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Gonçalves, Marta, Ana Margarida Madureira, Aida Duarte, Luis Catarino, Ana Monteiro, and Generosa Teixeira. "Zanthoxylum zanthoxyloides and Zanthoxylum leprieurii: a micromorphological, phytochemical and antibacterial evaluation." Annals of Medicine 51, sup1 (2019): 81. http://dx.doi.org/10.1080/07853890.2018.1561716.

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Ogunwolu, E. O., J. O. Igoli, and N. N. Longs. "Reduction in Reproductive Fitness ofCallosobruchus maculatusF. Exposed toZanthoxylum zanthoxyloides(Lam.) Waterm." Journal of Herbs, Spices & Medicinal Plants 6, no. 1 (1998): 19–27. http://dx.doi.org/10.1300/j044v06n01_03.

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Couillerot, Eric, Catherine Caron, Leopold Comoe, et al. "Benzophenanthridine and furoquinoline accumulation in cell suspension cultures of Fagara zanthoxyloides." Phytochemistry 37, no. 2 (1994): 425–28. http://dx.doi.org/10.1016/0031-9422(94)85072-0.

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Zahoui, S. O., N. G. Zirihi, Y. T. Soro, and F. Traore. "Effet hypotenseur d’un extrait aqueux de Zanthoxylum zanthoxyloides (Lam.) Waterman (Rutaceae)." Phytothérapie 8, no. 6 (2010): 359–69. http://dx.doi.org/10.1007/s10298-010-0587-4.

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A.O., Olusola, Ogidan T.O., Olusola A.O., Elekan A. O., Ekun O.E, and Onoagbe I. O. "ANTIMICROBIAL AND ANTIOXIDANT PROPERTIES OF FLAVONOIDS-RICH FRACTION OF ZANTHOZYLUM ZANTHOXYLOIDES LEAF." Journal of Bio Innovation 10, no. 1 (2021): 359–77. http://dx.doi.org/10.46344/jbino.2021.v010i01.31.

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Olusola, A. O., A. O. Elekan, A. O. Olusola, T. O. Ogidan, O. E. Ekun, and I. O. Onoagbe. "Evaluation of The Antimicrobial Activity of Saponins-Rich Fraction of Zanthoxylum zanthoxyloides Leaf." Journal of Medical and Biological Science Research 6, no. 3 (2020): 25–28. http://dx.doi.org/10.36630/jmbsr_20004.

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Ogunbolude, Yetunde, Mohammad Ibrahim, Olusola Elekofehinti, et al. "Effects of Tapinanthus globiferus and Zanthoxylum zanthoxyloides extracts on human leukocytes in vitro." Journal of Intercultural Ethnopharmacology 3, no. 4 (2014): 167. http://dx.doi.org/10.5455/jice.20140826110059.

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Cisse, Salimatou, Aime Ainin Somboro, Mamadou Badiaga, Niaboula Dembele, Nah Traore, and Pierre Chalard. "PHYTOCHIMIE E.T ACTIVITE ANTALGIQUE DE ZANTHOXYLUM ZANTHOXYLOIDES (LAM.) WATERMAN (RUTACEAE) RECOLTE AU MALI." International Journal of Advanced Research 12, no. 06 (2024): 1419–25. http://dx.doi.org/10.21474/ijar01/19005.

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Zanthoxylum zanthoxyloidesest une plantemedicinale de la famille des Rutaceae, largement utilisee en medecinetraditionnelle au Mali dans le traitement de nombreuses maladies dont la douleur.Lobjectif de letudeetaitdevaluerlactiviteantalgique des extraits (methanolique, acetate dethyle, butanolique et aqueux)des feuilles, tiges et racines de cette plante. Les constituants chimiques ont ete caracterises par les reactions en tube. Lactiviteantalgique des extraits a ete evaluee en utilisant le test de contorsion a travers la douleurinduite par lacideacetique chez des souris. Le screening phytochim
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Agbo, Elizabeth O., John V. Anyam, Cyprian T. Agber, et al. "Antitrypanosomal and Antileishmanial Activities of Tacca leontopetaloides Tubers and Zanthoxylum zanthoxyloides Stem Bark." Molecules 30, no. 11 (2025): 2468. https://doi.org/10.3390/molecules30112468.

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The phytochemical screening of extracts of Tacca leontopetaloides tubers has afforded the isolation of two novel chalcones, tarkalynins A and B, along with taccalonolide A and its 12-propanoate. The screening of Zanthoxylum zanthoxyloides stem bark yielded taraxerol acetate, dihydrochelerythrin and fagaramide. These compounds were obtained through column and thin-layer chromatography and identified using NMR and LC-HRMS. The compounds were tested against Trypanosoma brucei brucei s427 and its multi-drug-resistant clone B48, against Trypanosoma evansi, Trypanosoma equiperdum and Trypanosoma con
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Ikumawoyi, V. O., O. Awodele, K. Rotimi, and Y. A. Fashina. "EVALUATION OF THE EFFECTS OF THE HYDRO-ETHANOLIC ROOT EXTRACT OF ZANTHOXYLUM ZANTHOXYLOIDES ON HEMATOLOGICAL PARAMETERS AND OXIDATIVE STRESS IN CYCLOPHOSPAMIDE TREATED RATS." African Journal of Traditional, Complementary and Alternative Medicines 13, no. 5 (2016): 153–59. http://dx.doi.org/10.21010/ajtcam.v13i5.20.

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Background: The use of cyclophosphamide in cancer therapy is usually associated with challenging immunosuppression which exposes patients to increased risk of anemia and necessitating preventive measures during therapy. This study was carried out to investigate the efficacy of the hydro-ethanolic extract of the root of Z. zanthoxyloides in preventing and/or improving cyclophosphamide induced myelosuppression and oxidative stress in rats. Materials and Methods: Animals were divided into 6 groups of 6 rats each and were pretreated oral doses of 75, 150 and 225 mg/kg of the extract for 7 days and
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Olushola-Siedoks, Abisola Ave-maria, Ukachi Ezinwa Igbo, Godfrey Asieba, Ibilola Adiza Damola, and Chima Cartney Igwe. "Elemental analysis and phytochemical characterisation of Zanthoxylum zanthoxyloides (Lam.) Zepern. and Timler stem bark." Journal of Pharmacognosy and Phytochemistry 9, no. 5 (2020): 41–46. http://dx.doi.org/10.22271/phyto.2020.v9.i5a.12420.

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Anne, Itemire Oghenekevwe, Ogbimi Oroboheru Andrew, and MacDonald Idu. "Phytochemistry and antimicrobial activity of Zanthoxylum zanthoxyloides root used as chewing stick in Nigeria." Journal of Phytopharmacology 2, no. 6 (2013): 1–7. http://dx.doi.org/10.31254/phyto.2013.2601.

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This study examined the antimicrobial activity of aqueous and ethanolic extracts of Zanthoxylum zanthoxyloides root fractioned with chloroform against oral microbial isolates. Oral swabs were collected from 25 patients with dental problems attending the Dental clinic of UBTH Benin City. The streak plate method was used to culture on Blood, Chocolate, MacConkey and Sabouraud agar plates and were incubated at 37°C for 24 h for bacteria and room temperature for 72 h for fungi. The paper disc diffusion method was used at 100 mg/ml, 200 mg/ml, 400 mg/ml and 800 mg/ml for antimicrobial determination
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C. Onyemowo, Agbulu. "Antimicrobial Activity of Zanthoxylum Zanthoxyloides Root Used as Chewing Stick (in Nigeria) on Oral Pathogens." International Scientific Research Journal 1, no. 07 (2015): 75–81. http://dx.doi.org/10.18483/irjsci.61.

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