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Journal articles on the topic 'Zebra danio Embryos Physiology'

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1

Chowdhury, Jayanta, Tapan Kumar Mandal, and Sandhimita Mondal. "Genotoxic impact of emerging contaminant amoxicillin residue on zebra fish (Danio rerio) embryos." Heliyon 6, no. 11 (2020): e05379. http://dx.doi.org/10.1016/j.heliyon.2020.e05379.

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Tolentino, Josephine Joy V. "Embryo-Toxicity and Teratogenicity of Derris elliptica Leaf Extract on Zebra Fish (Danio rerio) Embryos." International Journal of Pure & Applied Bioscience 4, no. 3 (2016): 16–20. http://dx.doi.org/10.18782/2320-7051.2293.

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3

Cowart, Dominique A., Stephanie M. Guida, S. Ismat Shah, and Adam G. Marsh. "Effects of Ag nanoparticles on survival and oxygen consumption of zebra fish embryos,Danio rerio." Journal of Environmental Science and Health, Part A 46, no. 10 (2011): 1122–28. http://dx.doi.org/10.1080/10934529.2011.590726.

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4

Nirmala, K., J. Sekarsari, and P. Suptijah. "Efficacy of Chitosan as Pb Remover and its Effect on Zebrafish (Danio rerio) Embryo Development." Jurnal Akuakultur Indonesia 5, no. 2 (2007): 157. http://dx.doi.org/10.19027/jai.5.157-165.

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<p>Chitosan is a by-product from crustacean carapas. Chitosan has a cationic polyelectrolyte activity, hence it can be used as remover of heavy metal from polluted water. This study was aimed to determine optimum concentration of chitosan to remove Pb, efficacy time in Pb removal and its effect on early development of zebrafish (<em>Danio rerio</em>) embryos. The treatments in this study was control, and chitosan concentration of 70, 85 and 100 mg/L. the results of this study showed that maximum reducing of Pb was obtained at the time of 48 and 72 hours after treatment by chi
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5

Mohiuddin Hafiz, Shazmin, Smital Sameer Kulkarni, and Mansee Kapil Thakur. "In-Vivo Toxicity Assessment of Biologically Synthesized Iron Oxide Nanoparticles in Zebrafish (Danio Rerio)." Biosciences, Biotechnology Research Asia 15, no. 2 (2018): 419–25. http://dx.doi.org/10.13005/bbra/2645.

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Nanoparticles are increasingly used for biomedical purposes. In the past decades, much attention has been paid to toxicity assessment of nanoparticles prior to clinical and biological applications. Iron oxide nanoparticles (IONPs) are being introduced into the consumer market significantly. Effects and accumulation patterns of IONPs were studied using zebrafish embryos. Nanoparticles of iron were synthesized by biological reduction of spinach, using 0.1 M Ferric Chloride. These nanoparticles were characterized by SEM-EDS, XRD, FTIR and AAS were found to have the size range of 100 to 250 nm. Fi
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6

Martins, Islane Cristina, and Pabyton Gonçalves Cadena. "ANTIEPILEPTIC DRUGS CAUSE LETHAL, SUBLETHAL, TERATOGENIC EFFECTS AND MORPHOMETRIC PARAMETERS ON EMBRYOS AND LARVAE OF ZEBRAFISH (DANIO RERIO)." Revista Ibero-Americana de Humanidades, Ciências e Educação 6, no. 12 (2020): 485–504. http://dx.doi.org/10.51891/rease.v6i12.663.

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No presente estudo, avaliamos os efeitos tóxicos das drogas antiepilépticas gabapentina (GAB), fenobarbital (PB), oxcarbazepina (OX) e lamotrigina (LTG), os efeitos letais, subletais, teratogênicos e parâmetros morfométricos em embriões e larvas de peixe-zebra (Danio ri). Um teste de toxicidade aguda foi realizado usando embriões de D. rerio de acordo com as diretrizes OECD 236 (2013). O teste de toxicidade aguda revelou que a mortalidade de animais aumentou com o passar do tempo (24 a 96 hpf) em animais expostos a GAB, PB, OX e LTG. Os efeitos subletais tiveram uma variação significativa (p &
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7

Tseng, Deng-Yu, Ming-Yi Chou, Yung-Che Tseng, et al. "Effects of stanniocalcin 1 on calcium uptake in zebrafish (Danio rerio) embryo." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 296, no. 3 (2009): R549—R557. http://dx.doi.org/10.1152/ajpregu.90742.2008.

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Stanniocalcin (STC) formerly called hypocalcin or teleocalcin, is a 50-kDa disulfide-linked homodimeric glycoprotein that was originally identified in fish and secreted from the corpuscles of Stannius (CS). One of the main functions of STC-1 is Ca2+ uptake inhibition; however, the mechanisms remain unknown. In the present study, we provide molecular evidence to elucidate how zebrafish STC-1 regulates Ca2+ uptake in zebrafish embryos. In a wide variety of tissues including the kidney, brain, gill, muscle, and skin, zstc-1 was expressed. Incubating zebrafish embryos in low-Ca2+ (0.02 mM) freshwa
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8

Hozzein, N. "Developmental effects of extracts produced by some newly isolated Actinobacteria on the heart of Zebra fish (Danio rerio) embryos." African Journal of Pharmacy and Pharmacology 7, no. 25 (2013): 1680–85. http://dx.doi.org/10.5897/ajpp2013.2983.

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9

Bipat, R., R. C. Soekhoe, I. Magali, J. A. Hasrat, J. R. Toelsie, and D. R. A. Mans. "Evaluation of Surinamese medicinal plants for their potential influence on angiogenesis in embryos of the zebra fish Danio rerio." Annals of Global Health 80, no. 3 (2014): 203. http://dx.doi.org/10.1016/j.aogh.2014.08.116.

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10

LeMoine, Christophe M. R., and Patrick J. Walsh. "Ontogeny of ornithine-urea cycle gene expression in zebrafish (Danio rerio)." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 304, no. 11 (2013): R991—R1000. http://dx.doi.org/10.1152/ajpregu.00411.2012.

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Although the majority of adult teleosts excrete most of their nitrogenous wastes as ammonia, several fish species are capable of producing urea early in development. In zebrafish, it is unclear whether this results from a functional ornithine-urea cycle (O-UC) and, if so, how it might be regulated. This study examined the spatiotemporal patterns of gene expression of four major O-UC enzymes: carbamoyl phosphate synthase III (CPSIII), ornithine transcarboxylase, arginosuccinate synthetase, and arginosuccinate lyase, using real-time PCR and whole mount in situ hybridization. In addition, we hypo
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11

Pelster, Bernd, and Warren W. Burggren. "Disruption of Hemoglobin Oxygen Transport Does Not Impact Oxygen-Dependent Physiological Processes in Developing Embryos of Zebra Fish ( Danio rerio )." Circulation Research 79, no. 2 (1996): 358–62. http://dx.doi.org/10.1161/01.res.79.2.358.

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12

Lance, S. L., A. S. Peterson, and M. Hagedorn. "Developmental expression of aquaporin-3 in zebrafish embryos (Danio rerio)." Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 138, no. 3 (2004): 251–58. http://dx.doi.org/10.1016/j.cca.2004.08.004.

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13

Braun, M. H., S. L. Steele, M. Ekker, and S. F. Perry. "Nitrogen excretion in developing zebrafish (Danio rerio): a role for Rh proteins and urea transporters." American Journal of Physiology-Renal Physiology 296, no. 5 (2009): F994—F1005. http://dx.doi.org/10.1152/ajprenal.90656.2008.

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Injection of antisense oligonucleotide morpholinos to elicit selective gene knockdown of ammonia (Rhag, Rhbg, and Rhcg1) or urea transporters (UT) was used as a tool to assess the relative importance of each transporter to nitrogen excretion in developing zebrafish ( Danio rerio). Knockdown of UT caused urea excretion to decrease by ∼90%, whereas each of the Rh protein knockdowns resulted in an ∼50% reduction in ammonia excretion. Contrary to what has been hypothesized previously for adult fish, each of the Rh proteins appeared to have a similar effect on total ammonia excretion, and thus all
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14

Cazenave, Jimena, María de los Ángeles Bistoni, Elke Zwirnmann, Daniel Alberto Wunderlin, and Claudia Wiegand. "Attenuating effects of natural organic matter on microcystin toxicity in zebra fish (Danio rerio) embryos—benefits and costs of microcystin detoxication." Environmental Toxicology 21, no. 1 (2006): 22–32. http://dx.doi.org/10.1002/tox.20151.

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15

Alimuddin, A. Octavera, O. Z. Arifin та K. Sumantadinata. "Characterization of β-Actin Promoter from Nile Tilapia (Oreochromis niloticus)". Jurnal Akuakultur Indonesia 7, № 2 (2008): 115. http://dx.doi.org/10.19027/jai.7.115-127.

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<p>Promoter is one of the factors determining the successful of transgenesis. In this study we isolated and characterized β-actin promoter from Nile tilapia (tiBP) towards production of autotransgenic tilapia. β-actin promoter has high activity in muscle. Sequence of tiBP promoter was isolated by using PCR method. Sequencing was performed using ABI PRISM 3100 machine. Analysis of sequences was conducted using GENETYX version 7 and TFBind softwares. DNA fragment of PCR amplification product digested from the vector cloning was then ligated with pEGFP-N1 to generate ptiBP-EGFP construct. T
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16

Cortemeglia, Cheryl, and Thomas L. Beitinger. "Projected US distributions of transgenic and wildtype zebra danios, Danio rerio, based on temperature tolerance data." Journal of Thermal Biology 31, no. 5 (2006): 422–28. http://dx.doi.org/10.1016/j.jtherbio.2006.01.011.

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17

Skauli, Kirsten S., Jon B. Reitan, and Bernt T. Walther. "Hatching in zebrafish (Danio rerio) embryos exposed to a 50 Hz magnetic field." Bioelectromagnetics 21, no. 5 (2000): 407–10. http://dx.doi.org/10.1002/1521-186x(200007)21:5<407::aid-bem10>3.0.co;2-v.

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18

Köktürk, Mine, Gonca Alak, and Muhammed Atamanalp. "The effects of n-butanol on oxidative stress and apoptosis in zebra fish (Danio rerio) larvae." Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 227 (January 2020): 108636. http://dx.doi.org/10.1016/j.cbpc.2019.108636.

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19

Liu, Sian-Tai, Ming-Yi Chou, Liang-Chun Wu, Jiun-Lin Horng, and Li-Yih Lin. "Transient receptor potential vanilloid 4 modulates ion balance through the isotocin pathway in zebrafish (Danio rerio)." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 318, no. 4 (2020): R751—R759. http://dx.doi.org/10.1152/ajpregu.00307.2019.

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Isotocin controls ion regulation through modulating the functions of ionocytes (also called mitochondria-rich cells or chloride cells). However, little is known about the upstream molecule of the isotocin system. Herein, we identify transient receptor potential vanilloid 4 (TRPV4), which regulates the mRNA and protein expressions of isotocin and affects ion regulation through the isotocin pathway. Double immunohistochemical results showed that TRPV4 is expressed in isotocinergic neurons in the hypothalamus of the adult zebrafish brain. To further elucidate the roles of TRPV4, we manipulated TR
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20

Gurley, Bain, John W. Finger, and Haruka Wada. "Sex-Specific Effects of Incubation Temperature on Embryonic Development of Zebra Finch (Taeniopygia guttata) Embryos." Physiological and Biochemical Zoology 91, no. 5 (2018): 1036–45. http://dx.doi.org/10.1086/699741.

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21

Gao, Li, Yong Zhou, JingYan Tang, and Shuhong Shen. "The Leukemia-Associated Rho Guanine Nucleotide Exchange Factor (LARG) /ARHGEF12 Is Important For Erythroid Differentiation." Blood 122, no. 21 (2013): 3682. http://dx.doi.org/10.1182/blood.v122.21.3682.3682.

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Abstract ARHGEF12,which was initially identified as a fusion partner of MLL in acute myeloid leukemia, is a regulatory protein involved in the GDP/GTP exchange reaction of the Rho A and activates a Rho-GTPase-dependent signaling pathway. However, the role of ARHGEF12 in hematopoiesis remains unknown. Here, we first report that ARHGEF12 takes part in erythroid differentiation not only in erythroleukemia cell line K562 but also in zebra fish based on knockdown technology. Although primitive hematopoiesis including erythroid differentiation progressed normally, double silencing of both orthologue
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22

Strecker, Ruben, Thomas-Benjamin Seiler, Henner Hollert, and Thomas Braunbeck. "Oxygen requirements of zebrafish (Danio rerio) embryos in embryo toxicity tests with environmental samples." Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 153, no. 3 (2011): 318–27. http://dx.doi.org/10.1016/j.cbpc.2010.12.002.

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23

Chang, Wei-Jen, Jiun-Lin Horng, Jia-Jiun Yan, Chung-Der Hsiao, and Pung-Pung Hwang. "The transcription factor, glial cell missing 2, is involved in differentiation and functional regulation of H+-ATPase-rich cells in zebrafish (Danio rerio)." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 296, no. 4 (2009): R1192—R1201. http://dx.doi.org/10.1152/ajpregu.90973.2008.

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H+-ATPase-rich (HR) cells in zebrafish are known to be involved in acid secretion and Na+ uptake mechanisms in zebrafish gills/skin; however, little is known about how HR cells are functionally regulated. In the present work, we studied the roles of Drosophila glial cell missing ( gcm), a cell fate-related transcription factor, in the differentiation and functional regulation of zebrafish HR cells. Zebrafish gcm2 ( zgcm2) was found to begin expression in zebrafish embryos at 10 h postfertilization (hpf), and to be extensively expressed in gills but only mildly so in eyes, heart, muscles, and t
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24

Holmberg, A. "Ontogeny of the gut motility control system in zebrafish Danio rerio embryos and larvae." Journal of Experimental Biology 207, no. 23 (2004): 4085–94. http://dx.doi.org/10.1242/jeb.01260.

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25

Félix, Luís, Carolina Lobato-Freitas, Sandra M. Monteiro, and Carlos Venâncio. "24-Epibrassinolide modulates the neurodevelopmental outcomes of high caffeine exposure in zebrafish (Danio rerio) embryos." Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 249 (November 2021): 109143. http://dx.doi.org/10.1016/j.cbpc.2021.109143.

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26

Sawle, Ashley D., and Andrew R. Cossins. "The use of zebrafish (Danio rerio) embryos in a high definition transcriptomic expression profiling approach to ecotoxicological investigations." Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 153, no. 2 (2009): S87. http://dx.doi.org/10.1016/j.cbpa.2009.04.079.

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27

Vutukuru, S. S., Jayasree Ganugapati, Vardhini Ganesh, P. Atheeksha, and Ravindra Babu Potti. "Endocrine disruption by Bisphenol A, polychlorinated biphenyls and polybrominated diphenyl ether, in zebra fish (Danio rerio) model: an in silico approach." Fish Physiology and Biochemistry 42, no. 6 (2016): 1541–55. http://dx.doi.org/10.1007/s10695-016-0239-x.

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28

Pan, Tien-Chien, Bo-Kai Liao, Chang-Jen Huang, Li-Yih Lin, and Pung-Pung Hwang. "Epithelial Ca2+ channel expression and Ca2+ uptake in developing zebrafish." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 289, no. 4 (2005): R1202—R1211. http://dx.doi.org/10.1152/ajpregu.00816.2004.

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The purpose of the present work was to study the possible role of the epithelial Ca2+ channel (ECaC) in the Ca2+ uptake mechanism in developing zebrafish ( Danio rerio). With rapid amplification of cDNA ends, full-length cDNA encoding the ECaC of zebrafish (zECaC) was cloned and sequenced. The cloned zECaC was 2,578 bp in length and encoded a protein of 709 amino acids that showed up to 73% identity with previously described vertebrate ECaCs. The zECaC was found to be expressed in all tissues examined and began to be expressed in the skin covering the yolk sac of embryos at 24 h postfertilizat
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Stengel, Daniel, Florian Zindler, and Thomas Braunbeck. "An optimized method to assess ototoxic effects in the lateral line of zebrafish (Danio rerio) embryos." Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 193 (March 2017): 18–29. http://dx.doi.org/10.1016/j.cbpc.2016.11.001.

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30

On, Caly, Christian R. Marshall, Steve F. Perry, et al. "Characterization of zebrafish (Danio rerio) NCX4: a novel NCX with distinct electrophysiological properties." American Journal of Physiology-Cell Physiology 296, no. 1 (2009): C173—C181. http://dx.doi.org/10.1152/ajpcell.00455.2008.

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Members of the Na+/Ca2+ exchanger (NCX) family are important regulators of cytosolic Ca2+ in myriad tissues and are highly conserved across a wide range of species. Three distinct NCX genes and numerous splice variants exist in mammals, many of which have been characterized in a variety of heterologous expression systems. Recently, however, we discovered a fourth NCX gene ( NCX4), which is found exclusively in teleost, amphibian, and reptilian genomes. Zebrafish ( Danio rerio) NCX4a encodes for a protein of 939 amino acids and shows a high degree of identity with known NCXs. Although knockdown
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31

S Velanganni, P Sivakumar, and S Miltonprabu. "Impact of environmentally relevant concentration of benzophenone-3 on antioxidant enzymes, oxidative stress markers and morphology of gills in Danio rerio (Hamilton)." GSC Biological and Pharmaceutical Sciences 14, no. 3 (2021): 189–96. http://dx.doi.org/10.30574/gscbps.2021.14.3.0043.

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The current investigation intended to evaluate the effect of Benzophenone-3 (BP-3) at the environmentally relevant concentration (44 μg/L) in the gills of Danio rerio through evaluating oxidative stress markers and histopathological analysis. The adult Zebra fish was exposed to BP-3 at environmentally relevant concentration for 45 days. During the experimental period of 15, 30 and 45 days, lipid peroxidation markers like thiobarbituric acid reactive substances (TBARS) and Hydrogen peroxide (H2O2), antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), Glutathione peroxidase (G
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32

Rehberger, Kristina, Lisa Baumann, Markus Hecker, and Thomas Braunbeck. "Intrafollicular thyroid hormone staining in whole-mount zebrafish (Danio rerio) embryos for the detection of thyroid hormone synthesis disruption." Fish Physiology and Biochemistry 44, no. 3 (2018): 997–1010. http://dx.doi.org/10.1007/s10695-018-0488-y.

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33

Rowe, R. I., and C. D. Eckhert. "Boron is required for zebrafish embryogenesis." Journal of Experimental Biology 202, no. 12 (1999): 1649–54. http://dx.doi.org/10.1242/jeb.202.12.1649.

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Boron is the only element known to be essential for plants, but only circumstantial evidence for essentiality exists in animals. We report here that boron is essential for the embryonic development of zebrafish (Danio rerio). Zebrafish were maintained in water with a boron concentration of 0.1 micromol l-1 or supplemented to a concentration of 45 micromol l-1 using ultrapure boric acid. Both groups were fed boron-depleted brine shrimp. This procedure depleted the boron content of the blastulas from low-boron parents to only 5 % of the boron content of the blastulas from boron-supplemented pare
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34

Markovich, Daniel, Alessandro Romano, Carlo Storelli, and Tiziano Verri. "Functional and structural characterization of the zebrafish Na+-sulfate cotransporter 1 (NaS1) cDNA and gene (slc13a1)." Physiological Genomics 34, no. 3 (2008): 256–64. http://dx.doi.org/10.1152/physiolgenomics.90234.2008.

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Sulfate plays an essential role during growth, development and cellular metabolism. In this study, we characterized the function and structure of the zebrafish ( Danio rerio) Na+-sulfate cotransporter 1 (NaS1) cDNA and gene ( slc13a1). Zebrafish NaS1 encodes a protein of 583 amino acids with 13 putative transmembrane domains. Expression of zebrafish NaS1 protein in Xenopus oocytes led to Na+-sulfate cotransport, which was significantly inhibited by thiosulfate, selenate, molybdate, and tungstate. Zebrafish NaS1 transport kinetics were: Vmax = 1,731.670 ± 92.853 pmol sulfate/oocyte·hour and Km
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35

Rodríguez-Fuentes, Gabriela, Fernando J. Rubio-Escalante, Elsa Noreña-Barroso, Karla S. Escalante-Herrera, and Daniel Schlenk. "Impacts of oxidative stress on acetylcholinesterase transcription, and activity in embryos of zebrafish (Danio rerio) following Chlorpyrifos exposure." Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 172-173 (June 2015): 19–25. http://dx.doi.org/10.1016/j.cbpc.2015.04.003.

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36

Fischer, Stephan, Nils Klüver, Kathleen Burkhardt-Medicke, et al. "Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos." BMC Biology 11, no. 1 (2013): 69. http://dx.doi.org/10.1186/1741-7007-11-69.

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37

Sarasquete, Carmen, María Úbeda-Manzanaro, and Juan B. Ortiz-Delgado. "Toxicity and non-harmful effects of the soya isoflavones, genistein and daidzein, in embryos of the zebrafish, Danio rerio." Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 211 (September 2018): 57–67. http://dx.doi.org/10.1016/j.cbpc.2018.05.012.

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38

Molich, A. "Determination of pH by microfluorometry: intracellular and interstitial pH regulation in developing early-stage fish embryos (Danio rerio)." Journal of Experimental Biology 208, no. 21 (2005): 4137–49. http://dx.doi.org/10.1242/jeb.01878.

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39

Holmberg, A. "The effects of endogenous and exogenous nitric oxide on gut motility in zebrafish Danio rerio embryos and larvae." Journal of Experimental Biology 209, no. 13 (2006): 2472–79. http://dx.doi.org/10.1242/jeb.02272.

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40

Ratanayotha, Adisorn, Takafumi Kawai, and Yasushi Okamura. "Real-time functional analysis of Hv1 channel in neutrophils: a new approach from zebrafish model." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 316, no. 6 (2019): R819—R831. http://dx.doi.org/10.1152/ajpregu.00326.2018.

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Voltage-gated proton channel (Hv1) has been studied in various immune cells, including neutrophils. However, most studies have taken an in vitro approach using isolated cells or primary cultured cells of mammals; therefore, limited evidence is available on the function of Hv1 in a physiological context. In this study, we have developed the in vivo system that enables real-time functional analysis of Hv1 using zebrafish embryos ( Danio rerio). Hvcn1-deficiency ( hvcn1−/−) in zebrafish completely abolished voltage-gated proton current, which is typically observed in wild-type neutrophils. Import
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41

Vogt, R. G., S. M. Lindsay, C. A. Byrd, and M. Sun. "Spatial patterns of olfactory neurons expressing specific odor receptor genes in 48-hour-old embryos of zebrafish Danio rerio." Journal of Experimental Biology 200, no. 3 (1997): 433–43. http://dx.doi.org/10.1242/jeb.200.3.433.

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Olfactory neurons have a complex phenotype characterized by their expression of a specific odor receptor (OR) gene and their targeting of an equally specific locus in the olfactory bulb. In the adult fish, olfactory neurons expressing specific ORs are broadly distributed in the epithelium, intermingling with neurons expressing other OR phenotypes. This distributed adult pattern has led to the suggestion that olfactory neuron phenotype is determined by a stochastic process, independent of external positional cues. However, when the fish olfactory system is established during embryogenesis it is
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42

Alimuddin, G. Yoshizaki, O. Carman, and T. Takeuchi. "Effectiveness of hCMV, mEF1a and mAct promoters on driving of foreign gene expression in transgenic zebrafish." Jurnal Akuakultur Indonesia 6, no. 1 (2007): 65. http://dx.doi.org/10.19027/jai.6.65-77.

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&lt;p&gt;Highly unsaturated fatty acids (HUFA), especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have long been recognized for its beneficial effect for human health and development. The D6 fatty acid desaturase is generally considered to be the rate-limiting factor in HUFA biosynthesis. Here, as the first step of study, we conducted experiment to select an appropriate construct that allows higher expression levels of masu salmon (&lt;em&gt;Oncorhynchus masou&lt;/em&gt;)&lt;em&gt; &lt;/em&gt;D6-desaturase gene in zebrafish (&lt;em&gt;Danio rerio&lt;/em&gt;) in order to inc
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43

Markin, Pavel A., Alex Brito, Natalia E. Moskaleva, et al. "Short- and medium-term exposures of diazepam induce metabolomic alterations associated with the serotonergic, dopaminergic, adrenergic and aspartic acid neurotransmitter systems in zebrafish (Danio rerio) embryos/larvae." Comparative Biochemistry and Physiology Part D: Genomics and Proteomics 38 (June 2021): 100816. http://dx.doi.org/10.1016/j.cbd.2021.100816.

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44

Perni, Stefano, Kurt C. Marsden, Matias Escobar, Stephen Hollingworth, Stephen M. Baylor, and Clara Franzini-Armstrong. "Structural and functional properties of ryanodine receptor type 3 in zebrafish tail muscle." Journal of General Physiology 145, no. 3 (2015): 173–84. http://dx.doi.org/10.1085/jgp.201411303.

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The ryanodine receptor (RyR)1 isoform of the sarcoplasmic reticulum (SR) Ca2+ release channel is an essential component of all skeletal muscle fibers. RyR1s are detectable as “junctional feet” (JF) in the gap between the SR and the plasmalemma or T-tubules, and they are required for excitation–contraction (EC) coupling and differentiation. A second isoform, RyR3, does not sustain EC coupling and differentiation in the absence of RyR1 and is expressed at highly variable levels. Anatomically, RyR3 expression correlates with the presence of parajunctional feet (PJF), which are located on the side
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Gündel, U., S. Kalkhof, M. vonBergen, R. Altenburger, and E. Küster. "Concentration–response concept in ecotoxicoproteomics: An optimised design for the detection of robust chemical stress associated protein markers: Effects of different concentrations of phenanthren to the proteome of Danio rerio embryos." Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 157 (September 2010): S42—S43. http://dx.doi.org/10.1016/j.cbpa.2010.06.119.

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Carnovali, Marta, Giuseppe Banfi, and Massimo Mariotti. "Zebrafish Models of Human Skeletal Disorders: Embryo and Adult Swimming Together." BioMed Research International 2019 (November 20, 2019): 1–13. http://dx.doi.org/10.1155/2019/1253710.

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Danio rerio (zebrafish) is an elective model organism for the study of vertebrate development because of its high degree of homology with human genes and organs, including bone. Zebrafish embryos, because of the optical clarity, small size, and fast development, can be easily used in large-scale mutagenesis experiments to isolate mutants with developmental skeletal defects and in high-throughput screenings to find new chemical compounds for the ability to revert the pathological phenotype. On the other hand, the adult zebrafish represents another powerful resource for pathogenic and therapeuti
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Rescan, Pierre-Yves, Bertrand Collet, Cecile Ralliere, et al. "Red and white muscle development in the trout (Oncorhynchus mykiss) as shown by in situ hybridisation of fast and slow myosin heavy chain transcripts." Journal of Experimental Biology 204, no. 12 (2001): 2097–101. http://dx.doi.org/10.1242/jeb.204.12.2097.

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SUMMARY The axial muscle of most teleost species consists of a deep bulk of fast-contracting white fibres and a superficial strip of slow-contracting red fibres. To investigate the embryological development of fast and slow muscle in trout embryos, we carried out single and double in situ hybridisation with fast and slow myosin heavy chain (MyHC)-isoform-specific riboprobes. This showed that the slow-MyHC-positive cells originate in a region of the somite close to the notochord. As the somite matures in a rostrocaudal progression, the slow-MyHC-positive cells appear to migrate radially away fr
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Navarro-Guillén, Carmen, Gabriella do Vale Pereira, André Lopes, Rita Colen, and Sofia Engrola. "Egg nutritional modulation with amino acids improved performance in zebrafish larvae." PLOS ONE 16, no. 4 (2021): e0248356. http://dx.doi.org/10.1371/journal.pone.0248356.

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New and more efficient methods to sustainably intensify Aquaculture production are essential to attain the seafood demand for direct human consumption in the near future. Nutrition has been identified as one strategy of early exposure that might affect animal early development and later phenotype. This strategy may have positive consequences in the modulation of fish digestive physiology, which will correlate with higher performance outputs. Thus, improving fish digestive efficiency will lead to higher productivity and lower biogenic emission from aquaculture facilities, minimising the impact
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Schwerte, T., and B. Pelster. "Digital motion analysis as a tool for analysing the shape and performance of the circulatory system in transparent animals." Journal of Experimental Biology 203, no. 11 (2000): 1659–69. http://dx.doi.org/10.1242/jeb.203.11.1659.

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The analysis of perfusion parameters using the frame-to-frame technique and the observation of small blood vessels in transparent animals using video microscopy can be tedious and very difficult because of the poor contrast of the images. Injection of a fluorescent probe (fluorescein isothiocynate, FITC) bound to a high-molecular-mass dextran improved the visibility of blood vessels, but the gray-scale histogram showed blurring at the edges of the vessels. Furthermore, injection of the fluorescent probe into the ventricle of small zebrafish (Danio rerio) embryos (body mass approximately 1 mg)
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AKBULUT, Cansu, Çağhan KIZIL, and Nazan Deniz YÖN. "Effects of Low Doses of Bisphenol A on Primordial Germ Cells in Zebrafish (Danio rerio) Embryos and Larvae." Kafkas Universitesi Veteriner Fakultesi Dergisi, 2013. http://dx.doi.org/10.9775/kvfd.2013.8600.

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