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Academic literature on the topic 'Zinc Corporation'
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Journal articles on the topic "Zinc Corporation"
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Oliinyk, Tetiana, Sergey Yefimenko, Zaure Abdrakhmanova, Andrey Kan, and Farida Issatayeva. "Online ore monitoring using EDXRF method on process conveyor belts at Kazakhmys Corporation LLC operations." E3S Web of Conferences 166 (2020): 02010. http://dx.doi.org/10.1051/e3sconf/202016602010.
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The paper discusses organizing online ore monitoring on process conveyor belts at the operations of Kazakhmys Corporation LLC using EDXRF method implemented as an ore-controlling station (OCS) targeting ore size of -300 mm. OCS is supposed to achieve the objective of providing reliable silver detection measurements in the range of 1+ ppm. Objects of monitoring: copper-containing polymetallic ores delivered to Zhezkazgan, Balkhash and Karagaily processing plants for treatment (target elements include copper, zinc, lead, silver, cadmium, and iron) as well as ores transported by the main underground feeder belt at Nurkazgan Mine (copper, zinc, lead, silver, molybdenum, and iron). The ultimate of the studies was to produce an online report on quality and quantities of ore and metals delivered from each of ore suppliers; to adjust the tonnages dispatched by the various shafts and open pits in the online mode; obtain reliable proof for unbiased redistribution of metals back to the mining operations. Equipment used during the studies: EDXRF OCS RLP21T. Key features of the unit are also discussed. The results of bench-scale testing as well as industrial application of OCS RLP-21T are discussed leading to the conclusion of successful online monitoring of silver in ores sized from +1 ppm to -300 mm. The photographs were provided by S. A. Yefimenko.
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Valera, Márcia Carneiro, Carlos Henrique Ribeiro Camargo, Alessandra Sverberi Carvalho, and Eduardo Ramalho Pereira Gama. "In vitro evaluation of apical microleakage using different root-end filling materials." Journal of Applied Oral Science 14, no. 1 (January 2006): 49–52. http://dx.doi.org/10.1590/s1678-77572006000100010.
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The objective of this study was to evaluate the apical leakage of retrograde cavities filled with Portland Cement (Concrebrás S/A-MG-Brazil), ProRoot MTA TM (Dentsply International, Johnson City, TN, USA) and Sealapex (Kerr Corporation, Orange, California, USA) with addition of zinc oxide (Odahcam Herpo Produtos Dentários Ltda, Rio de Janeiro, RJ, Brazil). Forty-two extracted single-rooted human teeth were decoronated and used for this study. The root canals were instrumented at 1.0mm short of the apical foramen using the step-back technique to an apical ISO size 60. The roots were obturated with gutta-percha points and sealer Sealapex (Kerr Corporation-USA) and then 3mm of each root apex was sectioned at a 90° angle. Ultrasonic retrograde preparation was performed with a diamond tip to 3mm depth and the roots were randomly divided into 3 groups according to the filling material: G1-Portland, G2-ProRoot MTA, G3- Sealapex zinc oxide-added cement. The root surfaces were covered with nail varnish up to 2mm from the apical foramen, immersed in simulated tissue fluid for 30 days, and then immersed in 0.2% Rhodamine B solution for 24 hours for evaluation of marginal leakage. The results showed mean leakage of 0.75, 0.35 and 0.35 for groups 1, 2 and 3, respectively; however, Kruskal-Wallis test revealed that there was no statistically significant difference among the results (p>0.05).
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Aparachita, Pornpim, Scott Carter, Afton Sawyer, Jared Harshman, Zach Rambo, and Terry Ward. "145 Effects of titrated levels of water soluble zinc amino acid complex on growth performance of nursery pigs." Journal of Animal Science 97, Supplement_2 (July 2019): 82–83. http://dx.doi.org/10.1093/jas/skz122.150.
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Abstract Previously, we reported that supplementing a water soluble zinc via drinking water (0 to 80 mg/L) to nursery pigs improved ADG and G:F. To evaluate the efficacy of higher titrated levels of this water soluble zinc amino acid complex (ProPath®Zn LQ, Zinpro Corporation, Eden Prairie, MN) on growth performance, 280 crossbred pigs (5.5 kg BW; 19 d of age) were randomly allotted to four water treatments (7 pens/treatment; 10 pigs/pen). The water treatments were 0, 40, 80 and 160 mg Zn/L of water. Pigs were fed in 4 dietary phases with complex, nutrient-dense, corn-soybean meal-based diets: Phase 1 and 2 (2,500 and 1,750 mg Zn as ZnO/kg; d 1–7 and 7–14, respectively) and Phase 3 and 4 (200 mg Cu as CuSO4/kg; d 14–23 and 23–42, respectively). Pigs and feeders were weighed weekly to determine ADG, ADFI, and G:F. Water meters were used to record and calculate water disappearance and zinc intake. Data were analyzed as a randomized complete block design. Orthogonal polynomial contrasts were used to determine linear and curvilinear effects. Water and total zinc intake increased linearly (P < 0.001) with increasing water zinc concentration. From d 0–14 when high dietary zinc was fed, there were no differences (P > 0.10) in ADG, ADFI, or G:F. However, from d 14–42 when basal levels of zinc were fed, quadratic improvements in ADG (0.545, 0.561, 0.578, 0.546 kg; P < 0.05) and G:F (0.686, 0.706, 0.723, 0.702; P < 0.01) were observed with increasing zinc via water. Similarly for d 0–42, ADG (0.435, 0.440, 0.454; 0.434 kg; P = 0.07), G:F (0.726, 0.740, 0.763, 0.749; P = 0.05) and average ending wt (23.73, 23.97, 24.55, 23.70 kg; P = 0.07) improved quadratically with increasing zinc. In conclusion, supplementing ProPath®Zn LQ via water resulted in improvements in ADG and G:F for nursery pigs.
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Baqir, Mohammad, and Richard L. Harkess. "Zinc Uptake by Pelargonium × hortorum Grown in Shredded Tire Rubber-amended Media." HortScience 32, no. 3 (June 1997): 485B—485. http://dx.doi.org/10.21273/hortsci.32.3.485b.
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On 2 Feb. 1996, rooted cuttings of Pelargonium × hortorum L. H. Bailey cvs. Tango and Blues were planted in 750-cm3 (14 cm in diameter) pots containing peatmoss mixed with shredded tire rubber (2–6.0 mm particle size) at 0%, 20%, 40%, 60%, or 80%. Plants were irrigated by hand, drip, or ebb-and-fl ood, and were arranged in a split-plot experimental design. A wetting agent (Aqua Gro 2000 L, Aquatrols Corporation, Cherry Hill, N.J.) was mixed at the rate of 6 ml per 3750 ml of water and 120 ml of solution was applied to each plant. Greenhouse studies indicated that geraniums could be grown successfully in media containing up to 20% shredded tire rubber by volume when irrigated by hand. Plants grown in media containing more than 20% rubber were observed to be slow-growing and chlorotic. Tissue analysis of the plants indicated significantly increased levels of zinc in plants grown in media containing high percentages of rubber. Geraniums grown in media containing 80% rubber and irrigated using ebb-and-fl ood benches had the significantly highest levels of foliar zinc. Media porosity, percent air space, and bulk density increased, while water holding capacity decreased with increasing amounts of shredded tire rubber added to the media.
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Amatangelo, Michael D., Chad C. Bjorklund, Anita K. Gandhi, Anke Klippel, Tom Daniel, Rajesh Chopra, Matthew Trotter, and Anjan Thakurta. "IMiD® Immunomodulatory Agents Promote Apoptosis in Multiple Myeloma Cells through Induction of TRAIL Expression." Blood 126, no. 23 (December 3, 2015): 5355. http://dx.doi.org/10.1182/blood.v126.23.5355.5355.
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Abstract Background: Immunomodulatory drugs exhibit several anti-Multiple Myeloma (MM) activities including: growth arrest, antiangiogenesis, inhibition of tumor necrosis factor-alpha signaling and induction of apoptosis. The mechanism of action of the IMiD® compounds lenalidomide and pomalidomide that are responsible for these effects are starting to become clear. IMiD® compounds directly bind Cereblon (CBRN), a substrate receptor of the cullin ring E3 ligase (CRL4), and induce CRL4CRBN -mediated degradation of the zinc finger transcriptional repressors Aiolos and Ikaros by ubiquitin-mediated proteolysis. However, direct links between Aiolos or Ikaros degradation via the CRBN-Cul4 complex to the anti-MM activities of IMiD® drugs are poorly understood. Methods and Results: IMiD® compound-induced apoptosis in MM cells is associated with extended duration of treatment and increased caspase-8 activity, but the precise mechanism of caspase-8 activation and delayed onset of apoptotic effects in response to treatment are unknown. Here we show that both lenalidomide and pomalidomide induce caspase-8, but not capsase-9 activity, in multiple MM cell lines after 3 days of treatment and apoptosis after 4 days without inducing significant changes in total caspase-8, c-FLIP (a casapse-8 inhibitory molecule) or caspase-3 gene expression. Bioinformatic analysis of public datasets revealed that that the pro-apoptotic protein TRAIL may be induced by IMiD® compound treatment in a CRBN dependent manner. We confirmed in multiple cell lines that IMiD® compound treatment or knockdown of Aiolos or Ikaros induces TRAIL gene expression. Furthermore, IMiD® compound treatment in pomalidomide resistant cells that lack CRBN expression failed to induce TRAIL gene expression suggesting TRAIL induction is regulated through the established IMiD® drug mediated CRBN-Aiolos/Ikaros pathway. ChIP-PCR analysis confirmed that TRAIL is a direct transcriptional target gene of Aiolos and Ikaros in MM cells. Incubation of cells with a TRAIL neutralizing antibody was sufficient to partially attenuate IMiD® induced apoptosis, thus confirming the role of TRAIL in IMiD® drug induced MM cell apoptosis. Furthermore, TRAIL secretion into the media of IMiD® compound treated cells was significantly increased only after 2 days treatment explaining the delayed induction of apoptosis in treated cells. Interestingly, MM cell lines that are intrinsically resistant to the apoptotic effects of IMiD® compounds, despite degrading Aiolos and Ikaros in response to drug, displayed a decrease in TRAIL sensitivity. Conclusions: Taken together this data indicates that IMiD® drugs induce caspase-8 mediated apoptosis by directly inducing TRAIL gene expression via degradation of Aiolos and Ikaros. Additionally, this suggests that therapeutic interventions that can increase MM cell sensitivity to TRAIL might act synergistically with IMiD® compounds. Disclosures Amatangelo: Celgene Corporation: Employment, Equity Ownership. Bjorklund:Celgene Corporation: Employment, Equity Ownership. Gandhi:Celgene: Employment, Equity Ownership. Klippel:Celgene Corporation: Employment, Equity Ownership. Daniel:Celgene Corporation: Employment, Equity Ownership. Chopra:Celgene Corporation: Employment, Equity Ownership. Trotter:Celgene Corporation: Employment. Thakurta:Celgene Corporation: Employment, Equity Ownership.
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Jeyaraju, Danny V., Ekta Kumari, Michael Amatangelo, Chad C. Bjorklund, Chih-Chao Hsu, and Anjan Thakurta. "ZFP91 Regulates Multiple Myeloma Cell Proliferation through IL-1β Mediated IL-6 Secretion in the Tumor Microenvironment." Blood 134, Supplement_1 (November 13, 2019): 4406. http://dx.doi.org/10.1182/blood-2019-129181.
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Multiple myeloma is a malignancy of terminally differentiated plasma cells that are primarily resident in the bone marrow. Despite novel therapies, myeloma remains a fatal disease. Through interactions with immune cells in the bone marrow microenvironment, myeloma cells have been shown to facilitate their own proliferation and drug resistance. Therefore, targeting the immune support cells in the myeloma bone marrow microenvironment could add further value to existing treatment regimens. ZFP91, a C2H2-type zinc-finger protein, is a substrate of IMID drugs (An et al, Nat. Commun. 2017). The downstream target of ZFP91 in myeloma has been elusive so far. Our myeloma-specific ZFP91 interactome data and recent publications indicate an immune related function for ZFP91. A recent study also indicated that treatment of healthy volunteers with iberdomide, impaired the ability of monocytes to secrete IL-1β in response to LPS (Schafer PH, et al. Ann Rheum Dis 2018). To further investigate this, we generated CRISPR knockouts of IKZF1, IKZF3 and ZFP91, three major substrates of lenalidomide and iberdomide, in THP-1 monocytic cells. Upon LPS induction, loss of ZFP91 impaired the ability of THP-1 monocytic cells to secrete IL-1β (WT 70 pg/ml of IL-1β vs ZFP91-/- 4.5 pg/ml of IL-1β). Loss of IKZF1/3, the other two substrates of lenalidomide and iberdomide did not impair IL-1β secretion. IL-1β is a known activator of IL-6, a critical cytokine for myeloma cell proliferation. As a next step, we created a co-culture model to mimic a minimal myeloma tumor microenvironment with ANBL-6 (IL-6 dependent) myeloma cell line and primary bone marrow stromal cells in the presence of pre-conditioned media from LPS stimulated THP-1 monocytes. Preconditioned media from ZFP91-/- monocytes impaired proliferation of myeloma cells in the co-culture model due to lack of IL-1β, the inducer of IL-6 from the stromal cells. Mechanistically, loss of ZFP91 impairs the TLR4 signaling pathway. Thus, targeting ZFP91 impairs proliferation of myeloma cells within the bone marrow microenvironment by acting in trans from monocytes. Our findings for the first time identify a tumor cell proliferative role for ZFP91 in the myeloma tumor microenvironment. In addition, it establishes ZFP91 as an immune substrate of lenalidomide and iberdomide and could be a key player that mediates the immune functions observed. Disclosures Jeyaraju: Celgene Corporation: Employment, Equity Ownership. Kumari:Celgene Corporation: Employment. Amatangelo:Celgene Corporation: Employment, Equity Ownership. Bjorklund:Celgene Corporation: Employment, Equity Ownership. Hsu:Celgene Corporation: Employment. Thakurta:Celgene: Employment, Equity Ownership.
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Aparachita, Pornpim, Scott Carter, Afton Sawyer, Jared Harshman, Terry Ward, and Zach Rambo. "294 The effects of titrated levels of water soluble zinc amino acid complex on immune response of nursery pigs." Journal of Animal Science 97, Supplement_3 (December 2019): 121–22. http://dx.doi.org/10.1093/jas/skz258.251.
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Abstract Previously, we reported that supplementing titrated levels of a water soluble zinc amino acid complex (ProPath®Zn LQ, Zinpro Corporation, Eden Prairie, MN) via water (0 to 80 mg/L) to nursery pigs resulted in a lower inflammatory response after LPS challenge. To evaluate the efficacy of higher titrated levels, 280 pigs (5.5 kg BW; 19-d old) were allotted randomly to water treatments: 0, 40, 80 and 160 mg Zn/L of water (7 pens/treatment; 10 pigs/pen). Pigs were fed corn-soybean meal based diets with added Zn as ZnO or Cu as CuSO4: Phase 1 (2,500 mg Zn/kg; d 1–7), Phase 2 (1,750 mg Zn/kg; d 7–14), Phase 3 (200 mg Cu/kg; d 14–23), and Phase 4 (200 mg Cu/kg; d 23–42). At d 23, pigs were challenged by i.m. injection of lipopolysaccharide (12 µg/kg BW). Blood, BW, and rectal temperature (RT) were obtained from two pigs per pen at h 0, 3, and 12 of the challenge. Increasing water zinc resulted in linear reductions in RT (P = 0.02) and serum TNF-α concentration (P = 0.05) at h 0 prior to LPS injection. Post-LPS injection, increasing water zinc decreased linearly RT at h 3 (P = 0.01) and serum Zn:Cu ratio at h 3 (P = 0.04) and 12 (P = 0.01), and decreased serum TNF-α concentration at all hours (quadratic, P < 0.05). Additionally, increasing water zinc tended (linear, P = 0.07) to attenuate the decrease in BW following LPS from h 0–12. However, there were no effects on serum and salivary CRP concentrations (P > 0.05) within 12 hours of LPS challenge. At d 42, salivary CRP concentration decreased (quadratic, P = 0.03) with increasing zinc. In conclusion, supplementing ProPath®Zn LQ via drinking water to nursery pigs mitigated the febrile response and decreased cytokine production during an acute immune challenge.
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Bhandari, Arjun, Archana Manandhar, Raj Kumar Singh, Pramita Suwal, and Prakash Kumar Parajuli. "A Comparative study to measure the horizontal condylar guidance obtained by protrusive interocclusal records and panoramic radiographic images in completely edentulous patients." Journal of College of Medical Sciences-Nepal 14, no. 1 (March 30, 2018): 21–27. http://dx.doi.org/10.3126/jcmsn.v14i1.18947.
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Background & Objectives:The study was conducted with objective to compare the horizontal condylar guidance (HCG) obtained by protrusive interocclusal records and panoramic radiographic images in completely edentulous patients.Materials & Methods:The horizontal condylar guidance was measured in 25 completely edentulous patients by protrusive interocclusal records using zinc oxide eugenol paste through a face bow transfer (HanauTM Spring bow, Whip Mix Corporation, USA) to a semi-adjustable articulator (HanauTM Wide-Vue Articulator, Whip Mix Corporation, USA). In the same patients, HCG was traced in the panoramic radiograph. The angles formed by the intersection of two lines: Frankfurt’s horizontal plane and posterior slope of articular eminence was measured using protractor to represent the horizontal condylar guidance angle on each side.Results:The mean difference between the horizontal condylar guidance angles values obtained using protrusive interocclusal record and panoramic radiograph was 2.68 degrees and 3.40 degrees for the right and the left side respectively, with the panoramic radiograph values being higher. This difference between the values was found to be highly significant between the two methods for the right side (t = 2.70, p = 0.012) and left side (t = 3.69, p = 0.001). A significant positive correlation was found between the horizontal condylar guidance obtained from protrusive interocclusal record and panoramic radiograph for the right (r = 0.643, p = 0.001) and left sides (r = 0.622, p = 0.001) separately.Conclusion:The panoramic radiographic tracing can be used to calculate the mean horizontal condylar guidance in the completely edentulous patients and these values can be used to programme semi-adjustable articulators avoiding the cumbersome process of obtaining protrusive interocclusal records.
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Astashkin, A. I., V. V. Babanov, A. A. Selivanov, E. A. Tkachenko, D. V. Gusev, and M. V. Tsarev. "IMPROVING THE HARDENABILITY OF MASSIVE FORGINGS FROM ALLOYS OF THE Al–Zn–Mg–Cu SYSTEM BY BALANCED ALLOYING WITH ZINC AND MAGNESIUM." Aviation Materials and Technologies, no. 2 (2021): 35–42. http://dx.doi.org/10.18577/2713-0193-2021-0-2-35-42.
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The paper presents the results of studies of the influence of the Zn:Mg ratio on the hardenability, structure and complex of mechanical and corrosive characteristics of forgings with 150 mm thickness made of alloys based on Al–Zn–Mg–Cu system, manufactured in the production conditions of metallurgical plants of JSC AMR and Public Corporation “KUMZ”. It has been determined that an alloy of the Al–Zn–Mg–Cu system with Zn:Mg ratio of not less than 4,1:1 and copper mass content of not more than 1.2% has a higher hardenability compared to the 1933 alloy of standard composition, which ensures homogeneous structure and indicators of mechanical and corrosion properties over the thickness of semi-finished pro-ducts; in metallurgical industry at the stage of manufacturing this allows reducing the residual quenching stresses in massive forgings by means of straightening by reduction in an as-quenched state.
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Aubakirova, Gulnara, Georgiy Rudko, and Farida Isataeva. "Assessment of metallurgical enterprises’ activities in Kazakhstan in the context of international trends." Economic Annals-ХХI 187, no. 1-2 (February 28, 2021): 121–30. http://dx.doi.org/10.21003/ea.v187-12.
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The geological industry of Kazakhstan is transiting to CRIRSCO, the international system of reporting standards for mineral reserves. In view of the set tasks, the problem of adjusting the geological and economic assessment of deposits is being updated in order to adapt it to the international requirements and to increase accessibility and transparency for a potential external investor. This research has been carried out on the basis of the Kazakhmys Corporation LLС, the largest international company engaged in exploring, mining and processing of various minerals. The authors of this paper have made an attempt to expand the geological and economic assessment of the enterprise by digitizing the key business processes. On the basis of the formed factual database of the geological and economic indicators and characteristics of the stratiform pyrite-copper-lead-zinc deposit Kusmuryn, which is part of the Kazakhmys Corporation LLС, the economic indicators of extracting associated components have been calculated. Digital transformation is a key area of technological development of the mining industry in Kazakhstan for the coming years. In this regard, automation of calculating the geological and economic assessment of the investigated field will allow the company not only to reduce investment and operating costs, but also to deepen the internal analytical work to monitor the effectiveness of the applied digital solutions. Transformation of the economy of Kazakhstan presupposes state support for promising regions. The article shows that transition of the Kusmuryn deposit to underground mining in the medium term will accelerate the solution of pressing regional problems and remove social tension in the monotowns adjacent to the deposit. In order to strengthen its position in the global economy, Kazakhstan strives to achieve socio-economic goals in the field of sustainable development. It has been established that changing the method of production and automation of business processes of the Kazakhmys Corporation LLС will have a positive effect on the energy efficiency due to more rational use of available technologies. The research will improve the validity of predictive management decisions to strengthen the financial and economic situation and the international positions of the mining and smelting enterprise.
Books on the topic "Zinc Corporation"
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Assistance, Massachusetts Dept of Environmental Protection Office of Technical. Zinc discharge reduction at the Lowell Corporation. Boston, Mass.]: Office of Technical Assistance, Executive Office of Environmental Affairs, Commonwealth of Massachusetts, 1991.
Find full textBook chapters on the topic "Zinc Corporation"
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James, S. E., L. L. Ludwig, and B. L. Motycka. "Improvements at the Electrolytic Zinc Plant of Big River Zinc Corporation, Sauget, Illinois, U.S.A." In Lead-Zinc 2000, 385–98. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118805558.ch24.
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Claassen, J. O., J. Rennie, W. H. van Niekerk, E. H. O. Meyer, and R. F. Sandenbergh. "Recent Developments in Iron Removal and Control at the Zinc Corporation of South Africa." In Electrometallurgy and Environmental Hydrometallurgy, 1675–90. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118804407.ch45.
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