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Journal articles on the topic 'Zona incerta'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 February 2022

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1

Bartho, P., A. Slezia, V. Varga, H. Bokor, D. Pinault, G. Buzsaki, and L. Acsady. "Cortical Control of Zona Incerta." Journal of Neuroscience 27, no. 7 (February 14, 2007): 1670–81. http://dx.doi.org/10.1523/jneurosci.3768-06.2007.

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2

Masri, Radi, Raimi L. Quiton, Jessica M. Lucas, Peter D. Murray, Scott M. Thompson, and Asaf Keller. "Zona Incerta: A Role in Central Pain." Journal of Neurophysiology 102, no. 1 (July 2009): 181–91. http://dx.doi.org/10.1152/jn.00152.2009.

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Central pain syndrome (CPS) is a debilitating condition that affects a large number of patients with a primary lesion or dysfunction in the CNS. Despite its discovery over a century ago, the pathophysiological processes underlying the development and maintenance of CPS are poorly understood. We recently demonstrated that activity in the posterior thalamus (PO) is tightly regulated by inhibitory inputs from zona incerta (ZI). Here we test the hypothesis that CPS is associated with abnormal inhibitory regulation of PO by ZI. We recorded single units from ZI and PO in animals with CPS resulting from spinal cord lesions. Consistent with our hypothesis, the spontaneous firing rate and somatosensory evoked responses of ZI neurons were lower in lesioned animals compared with sham-operated controls. In PO, neurons recorded from lesioned rats exhibited significantly higher spontaneous firing rates and greater responses to noxious and innocuous stimuli applied to the hindpaw and to the face. These changes were not associated with increased afferent drive from the spinal trigeminal nucleus or changes in the ventroposterior thalamus. Thus CPS can result from suppressed inputs from the inhibitory nucleus zona incerta to the posterior thalamus.

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3

Park, Anthony, Kathleen Hoffman, and Asaf Keller. "Roles of GABAA and GABAB receptors in regulating thalamic activity by the zona incerta: a computational study." Journal of Neurophysiology 112, no. 10 (November 15, 2014): 2580–96. http://dx.doi.org/10.1152/jn.00282.2014.

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The posterior thalamic nucleus (PO) is a higher order nucleus heavily implicated in the processing of somatosensory information. We have previously shown in rodent models that activity in PO is tightly regulated by inhibitory inputs from a GABAergic nucleus known as the zona incerta (ZI). The level of incertal inhibition varies under both physiological and pathological conditions, leading to concomitant changes in PO activity. These changes are causally linked to variety of phenomena from altered sensory perception to pathological pain. ZI regulation of PO is mediated by GABAA and GABAB receptors (GABAAR and GABABR) that differ in their binding kinetics and their electrophysiological properties, suggesting that each may have distinct roles in incerto-thalamic regulation. We developed a computational model to test this hypothesis. We created a two-cell Hodgkin-Huxley model representing PO and ZI with kinetically realistic GABAAR- and GABABR-mediated synapses. We simulated spontaneous and evoked firing in PO and observed how these activities were affected by inhibition mediated by each receptor type. Our model predicts that spontaneous PO activity is preferentially regulated by GABABR-mediated mechanisms, while evoked activity is preferentially regulated by GABAAR. Our model also predicts that modulation of ZI firing rate and synaptic GABA concentrations is an effective means to regulate the incerto-thalamic circuit. The coupling of distinct functions to GABAAR and GABABR presents an opportunity for the development of therapeutics, as particular aspects of incerto-thalamic regulation can be targeted by manipulating the corresponding receptor class. Thus these findings may provide interventions for pathologies of sensory processing.

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4

Trageser, Jason C., Kathryn A. Burke, Radi Masri, Ying Li, Larisa Sellers, and Asaf Keller. "State-Dependent Gating of Sensory Inputs by Zona Incerta." Journal of Neurophysiology 96, no. 3 (September 2006): 1456–63. http://dx.doi.org/10.1152/jn.00423.2006.

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We have previously shown that the GABAergic nucleus zona incerta (ZI) suppresses vibrissae-evoked responses in the posterior medial (POm) thalamus of the rodent somatosensory system. We proposed that this inhibitory incerto-thalamic pathway regulates POm responses during different behavioral states. Here we tested the hypothesis that the cholinergic reticular activating system, implicated in regulating states of arousal, modulates ZI activity. We show that stimulation of brain stem cholinergic nuclei (laterodorsal tegmental and pedunculopontine tegmental) results in suppression of spontaneous firing of ZI neurons. Iontophoretic application of the cholinergic agonist carbachol to ZI neurons suppresses both their spontaneous firing and their vibrissae-evoked responses. We also found that carbachol application to an in vitro slice preparation suppresses spontaneous firing of neurons in the ventral sector of ZI (ZIv). Finally, we demonstrate that the majority of ZIv neurons contain parvalbumin and project to POm. Based on these results, we present the state-dependent gating hypothesis, which states that differing behavioral states—regulated by the brain stem cholinergic system—modulate ZI activity, thereby regulating the response properties of higher-order nuclei such as POm.

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5

Lin, C., M. Nicolelis, J. Schneider, and J. Chapin. "GABAergic pathway from zona incerta to neocortex: clarification." Science 251, no. 4998 (March 8, 1991): 1162. http://dx.doi.org/10.1126/science.1706534.

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6

LIN, C. S., M. A. L. NICOLELIS, J. S. SCHNEIDER, and J. K. CHAPIN. "GABAergic Pathway from Zona Incerta to Neocortex: Clarification." Science 251, no. 4998 (March 8, 1991): 1162. http://dx.doi.org/10.1126/science.251.4998.1162-c.

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7

Venkataraman, Archana, Natalia Brody, Preethi Reddi, Jidong Guo, Donald Gordon Rainnie, and Brian George Dias. "Modulation of fear generalization by the zona incerta." Proceedings of the National Academy of Sciences 116, no. 18 (April 9, 2019): 9072–77. http://dx.doi.org/10.1073/pnas.1820541116.

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Fear expressed toward threat-associated stimuli is an adaptive behavioral response. In contrast, the generalization of fear responses toward nonthreatening cues is a maladaptive and debilitating dimension of trauma- and anxiety-related disorders. Expressing fear to appropriate stimuli and suppressing fear generalization require integration of relevant sensory information and motor output. While thalamic and subthalamic brain regions play important roles in sensorimotor integration, very little is known about the contribution of these regions to the phenomenon of fear generalization. In this study, we sought to determine whether fear generalization could be modulated by the zona incerta (ZI), a subthalamic brain region that influences sensory discrimination, defensive responses, and retrieval of fear memories. To do so, we combined differential intensity-based auditory fear conditioning protocols in mice with C-FOS immunohistochemistry and designer receptors exclusively activated by designer drugs (DREADDs)-based manipulation of neuronal activity in the ZI. C-FOS immunohistochemistry revealed an inverse relationship between ZI activation and fear generalization: The ZI was less active in animals that generalized fear. In agreement with this relationship, chemogenetic inhibition of the ZI resulted in fear generalization, while chemogenetic activation of the ZI suppressed fear generalization. Furthermore, targeted stimulation of GABAergic cells in the ZI reduced fear generalization. To conclude, our data suggest that stimulation of the ZI could be used to treat fear generalization in the context of trauma- and anxiety-related disorders.

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8

Thaker, Ashesh A., Kartik M. Reddy, John A. Thompson, Pamela David Gerecht, Mark S. Brown, Aviva Abosch, Steven G. Ojemann, and Drew S. Kern. "Coronal Gradient Echo MRI to Visualize the Zona Incerta for Deep Brain Stimulation Targeting in Parkinson’s Disease." Stereotactic and Functional Neurosurgery 99, no. 5 (2021): 443–50. http://dx.doi.org/10.1159/000515772.

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<b><i>Introduction:</i></b> Deep brain stimulation of the zona incerta is effective at treating tremor and other forms of parkinsonism. However, the structure is not well visualized with standard MRI protocols making direct surgical targeting unfeasible and contributing to inconsistent clinical outcomes. In this study, we applied coronal gradient echo MRI to directly visualize the rostral zona incerta in Parkinson’s disease patients to improve targeting for deep brain stimulation. <b><i>Methods:</i></b> We conducted a prospective study to optimize and evaluate an MRI sequence to visualize the rostral zona incerta in patients with Parkinson’s disease (<i>n</i> = 31) and other movement disorders (<i>n</i> = 13). We performed a contrast-to-noise ratio analysis of specific regions of interest to quantitatively assess visual discrimination of relevant deep brain structures in the optimized MRI sequence. Regions of interest were independently assessed by 2 neuroradiologists, and interrater reliability was assessed. <b><i>Results:</i></b> Rostral zona incerta and subthalamic nucleus were well delineated in our 5.5-min MRI sequence, indicated by excellent interrater agreement between neuroradiologists for region-of-interest measurements (>0.90 intraclass coefficient). Mean contrast-to-noise ratio was high for both rostral zona incerta (6.39 ± 3.37) and subthalamic nucleus (17.27 ± 5.61) relative to adjacent white matter. There was no significant difference between mean signal intensities or contrast-to-noise ratio for Parkinson’s and non-Parkinson’s patients for either structure. <b><i>Discussion/Conclusion:</i></b> Our optimized coronal gradient echo MRI sequence delineates subcortical structures relevant to traditional and novel deep brain stimulation targets, including the zona incerta, with high contrast-to-noise. Future studies will prospectively apply this sequence to surgical planning and postimplantation outcomes.

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9

Wang, Xiyue, Xiao-lin Chou, Li I. Zhang, and Huizhong Whit Tao. "Zona Incerta: An Integrative Node for Global Behavioral Modulation." Trends in Neurosciences 43, no. 2 (February 2020): 82–87. http://dx.doi.org/10.1016/j.tins.2019.11.007.

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10

POWER, BRIAN D., CATHERINE A. LEAMEY, and JOHN MITROFANIS. "Evidence for a visual subsector within the zona incerta." Visual Neuroscience 18, no. 2 (March 2001): 179–86. http://dx.doi.org/10.1017/s0952523801182027.

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11

Barthó, P., T. F. Freund, and L. Acsády. "Selective GABAergic innervation of thalamic nuclei from zona incerta." European Journal of Neuroscience 16, no. 6 (September 2002): 999–1014. http://dx.doi.org/10.1046/j.1460-9568.2002.02157.x.

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12

Ossowska, Krystyna. "Zona incerta as a therapeutic target in Parkinson’s disease." Journal of Neurology 267, no. 3 (August 2, 2019): 591–606. http://dx.doi.org/10.1007/s00415-019-09486-8.

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13

Blomstedt, Patric, Anders Fytagoridis, Mattias Åström, Jan Linder, Lars Forsgren, and Marwan I. Hariz. "Unilateral caudal zona incerta deep brain stimulation for Parkinsonian tremor." Parkinsonism & Related Disorders 18, no. 10 (December 2012): 1062–66. http://dx.doi.org/10.1016/j.parkreldis.2012.05.024.

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14

Gorbachevskaya, A. I., and O. G. Chivileva. "Structural organization of the zona incerta of the dog diencephalon." Neuroscience and Behavioral Physiology 38, no. 6 (July 2008): 573–78. http://dx.doi.org/10.1007/s11055-008-9023-4.

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15

Gorbachevskaya, A. I. "Striopallidal Projections of the Zona Incerta of the Dog Diencephalon." Neuroscience and Behavioral Physiology 41, no. 2 (January 12, 2011): 153–56. http://dx.doi.org/10.1007/s11055-011-9392-y.

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16

Brudzynski, Stefan M., James W. Cruickshank, and Richard S. McLachlan. "Cholinergic Mechanisms in Generalized Seizures: Importance of the Zona Incerta." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 22, no. 2 (May 1995): 116–20. http://dx.doi.org/10.1017/s031716710004018x.

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AbstractObjective:Stimulation of the central cholinergic system results in generalized epileptic seizures. The goal of this study was to map the epileptogenic effects of the cholinergic agonist, carbachol injected into different sites of the basal forebrain and diencephalon of the rat brain.Methods:Carbachol was injected directly into the brain in a dose of 1 or 3 (jg. Seizures were assessed behaviourally on a five-stage scale with electroencephalographic controls. Seizures at stage 1 were the least severe and those at stage 5 the most severe.Results:Injections of high dose carbachol (3 (jg) induced seizures from 40% of all injected brain sites. Injections of low dose carbachol (1 ug) or isotonic saline into the same brain sites did not cause any behavioural or electrographic seizures. The majority of sites (84%) producing generalized seizures (stage 5) were concentrated in or around the zona incerta.Conclusions:Within the anatomical limits of the study, the zona incerta is the area most sensitive to carbachol-induced generalized seizures.

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17

Sundstedt, Stina, Erik Nordh, Jan Linder, Johanna Hedström, Caterina Finizia, and Katarina Olofsson. "Swallowing Quality of Life After Zona Incerta Deep Brain Stimulation." Annals of Otology, Rhinology & Laryngology 126, no. 2 (November 13, 2016): 110–16. http://dx.doi.org/10.1177/0003489416675874.

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18

Trageser, J. C. "Reducing the Uncertainty: Gating of Peripheral Inputs by Zona Incerta." Journal of Neuroscience 24, no. 40 (October 6, 2004): 8911–15. http://dx.doi.org/10.1523/jneurosci.3218-04.2004.

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19

Mok, D., and G. J. Mogenson. "Contribution of zona incerta to osmotically induced drinking in rats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 251, no. 5 (November 1, 1986): R823—R832. http://dx.doi.org/10.1152/ajpregu.1986.251.5.r823.

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Spontaneous extracellular activity was recorded from single neurons in the rostral zona incerta (ZI) of urethan-anesthetized rats. Ventricular injections of hyperosmotic saline (1 or 2 microliter of NaCl solutions with osmolarities of 0.6 or 1.2 osmol/l) and distilled water (1 or 2 microliter) at the level of the anteroventral third ventricle (AV3V) changed the firing rate of ZI neurons. By comparison, ventricular injections of osmotic solutions at the level of the dorsal third ventricle were relatively ineffective. Injections of osmotic solutions (0.2 or 0.5 microliter of 1.2 osmol/l NaCl) into the medial preoptic area (MPO) also changed the firing rate of ZI neurons, whereas control injections into the caudate putamen were ineffective. In another series of rats, injections of procaine into the region of the rostral ZI significantly reduced drinking to injections of hyperosmotic saline into the ipsi- but not the contralateral MPO. The ZI, AV3V, and MPO have previously been reported to contribute to the neural regulation of fluid intake. These findings provide additional evidence for a role of the ZI in drinking and suggest that part of the central pathway for osmotic thirst involves a projection to neurons in the ZI from osmoreceptors in the MPO.

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20

Merello, Marcelo, Eduardo Tenca, and Daniel Cerquetti. "Neuronal activity of the zona incerta in Parkinson's disease patients." Movement Disorders 21, no. 7 (March 13, 2006): 937–43. http://dx.doi.org/10.1002/mds.20834.

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21

Kolmac, Christian I., Brian D. Power, and John Mitrofanis. "Patterns of connections between zona incerta and brainstem in rats." Journal of Comparative Neurology 396, no. 4 (July 13, 1998): 544–55. http://dx.doi.org/10.1002/(sici)1096-9861(19980713)396:4<544::aid-cne10>3.0.co;2-g.

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22

Lin, C., M. Nicolelis, J. Schneider, and J. Chapin. "A major direct GABAergic pathway from zona incerta to neocortex." Science 248, no. 4962 (June 22, 1990): 1553–56. http://dx.doi.org/10.1126/science.2360049.

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23

Ma, Terence P. "Saccade-related omnivectoral pause neurons in the primate zona incerta." NeuroReport 7, no. 15 (November 1996): 2713–16. http://dx.doi.org/10.1097/00001756-199611040-00061.

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24

Mitrofanis, J. "Some certainty for the “zone of uncertainty”? Exploring the function of the zona incerta." Neuroscience 130, no. 1 (January 2005): 1–15. http://dx.doi.org/10.1016/j.neuroscience.2004.08.017.

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25

Petronilho, Ariane, Gláucia M. Reis, Quintino M. Dias, Rafael S. Fais, and Wiliam A. Prado. "Antinociceptive effect of stimulating the zona incerta with glutamate in rats." Pharmacology Biochemistry and Behavior 101, no. 3 (May 2012): 360–68. http://dx.doi.org/10.1016/j.pbb.2012.01.022.

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26

Power, Brian D., and John Mitrofanis. "Evidence for extensive inter-connections within the zona incerta in rats." Neuroscience Letters 267, no. 1 (May 1999): 9–12. http://dx.doi.org/10.1016/s0304-3940(99)00313-4.

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27

Mitrofanis, John, Keyoumars Ashkan, Bradley A. Wallace, and Alim-Louis Benabid. "Chemoarchitectonic heterogeneities in the primate zona incerta: Clinical and functional implications." Journal of Neurocytology 33, no. 4 (July 2004): 429–40. http://dx.doi.org/10.1023/b:neur.0000046573.28081.dd.

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28

Sundstedt, S., K. Olofsson, J. van Doorn, J. Linder, E. Nordh, and P. Blomstedt. "Swallowing function in Parkinson's patients following Zona Incerta deep brain stimulation." Acta Neurologica Scandinavica 126, no. 5 (March 4, 2012): 350–56. http://dx.doi.org/10.1111/j.1600-0404.2012.01658.x.

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29

Johansson, L., S. Möller, K. Olofsson, J. Linder, E. Nordh, P. Blomstedt, J. van Doorn, and F. Karlsson. "Word-level intelligibility after caudal zona incerta stimulation for Parkinson's disease." Acta Neurologica Scandinavica 130, no. 1 (December 17, 2013): 27–33. http://dx.doi.org/10.1111/ane.12210.

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30

Liu, Kai, Juhyun Kim, Dong Won Kim, Yi Stephanie Zhang, Hechen Bao, Myrto Denaxa, Szu-Aun Lim, et al. "Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep." Nature 548, no. 7669 (August 23, 2017): 582–87. http://dx.doi.org/10.1038/nature23663.

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31

Kerl, Hans U. "Imaging for deep brain stimulation: The zona incerta at 7 Tesla." World Journal of Radiology 5, no. 1 (2013): 5. http://dx.doi.org/10.4329/wjr.v5.i1.5.

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32

Power, Brian D., and John Mitrofanis. "Zona incerta: Substrate for contralateral interconnectivity in the thalamus of rats." Journal of Comparative Neurology 436, no. 1 (2001): 52–63. http://dx.doi.org/10.1002/cne.1053.

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33

Sundstedt, Stina, Lina Holmén, Elin Rova, Jan Linder, Erik Nordh, and Katarina Olofsson. "Swallowing safety in Parkinson's disease after zona incerta deep brain stimulation." Brain and Behavior 7, no. 6 (April 21, 2017): e00709. http://dx.doi.org/10.1002/brb3.709.

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34

Guehl, D., A. Vital, E. Cuny, U. Spampinato, A. Rougier, B. Bioulac, and P. Burbaud. "POSTMORTEM PROOF OF EFFECTIVENESS OF ZONA INCERTA STIMULATION IN PARKINSON DISEASE." Neurology 70, Issue 16, Part 2 (April 14, 2008): 1489–90. http://dx.doi.org/10.1212/01.wnl.0000310426.18409.11.

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35

Watson, Charles, Christopher R. P. Lind, and Meghan G. Thomas. "The anatomy of the caudal zona incerta in rodents and primates." Journal of Anatomy 224, no. 2 (October 21, 2013): 95–107. http://dx.doi.org/10.1111/joa.12132.

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36

Vanhatalo, Sampsa, and Seppo Soinila. "Superfluous expression of tryptophan hydroxylase in the zona incerta dopaminergic neurones." NeuroReport 7, no. 18 (November 1996): 2889–92. http://dx.doi.org/10.1097/00001756-199611250-00016.

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37

Plaha, P., S. Khan, and S. S. Gill. "Bilateral stimulation of the caudal zona incerta nucleus for tremor control." Journal of Neurology, Neurosurgery & Psychiatry 79, no. 5 (May 1, 2008): 504–13. http://dx.doi.org/10.1136/jnnp.2006.112334.

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38

Mitrofanis, John. "Evidence for an auditory subsector within the zona incerta of rats." Anatomy and Embryology 205, no. 5-6 (October 1, 2002): 453–62. http://dx.doi.org/10.1007/s00429-002-0268-3.

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39

Shaw, Victoria, and John Mitrofanis. "Anatomical evidence for somatotopic maps in the zona incerta of rats." Anatomy and Embryology 206, no. 1-2 (December 1, 2002): 119–30. http://dx.doi.org/10.1007/s00429-002-0280-7.

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40

Mitrofanis, J., and Ravi deFonseka. "Organisation of connections between the zona incerta and the interposed nucleus." Anatomy and Embryology 204, no. 2 (August 1, 2001): 153–59. http://dx.doi.org/10.1007/s004290100187.

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41

TONELLI, L., and E. CHIARAVIGLIO. "Dopaminergic neurons in the zona incerta modulates ingestive behavior in rats." Physiology & Behavior 58, no. 4 (October 1995): 725–29. http://dx.doi.org/10.1016/0031-9384(95)00128-6.

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42

Shaw, Fu-Zen, Yi-Fang Liao, Ruei-Feng Chen, Yu-Hsing Huang, and Rick C. S. Lin. "The zona incerta modulates spontaneous spike-wave discharges in the rat." Journal of Neurophysiology 109, no. 10 (May 15, 2013): 2505–16. http://dx.doi.org/10.1152/jn.00750.2011.

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The contribution of the zona incerta (ZI) of the thalamus on spike-wave discharges (SWDs) was investigated. Chronic recordings of bilateral cortices, bilateral vibrissa muscle, and unilateral ZI were performed in Long-Evans rats to examine the functional role of SWDs. Rhythmic ZI activity appeared at the beginning of SWD and was accompanied by higher-oscillation frequencies and larger spike magnitudes. Bilateral lidocaine injections into the mystacial pads led to a decreased oscillation frequency of SWDs, but the phenomenon of ZI-related spike magnitude enhancement was preserved. Moreover, 800-Hz ZI microstimulation terminates most of the SWDs and whisker twitching (WT; >80%). In contrast, 200-Hz ZI microstimulation selectively stops WTs but not SWDs. Stimulation of the thalamic ventroposteriomedial nucleus showed no obvious effect on terminating SWDs. A unilateral ZI lesion resulted in a significant reduction of 7- to 12-Hz power of both the ipsilateral cortical and contralateral vibrissae muscle activities during SWDs. Intraincertal microinfusion of muscimol showed a significant inhibition on SWDs. Our present data suggest that the ZI actively modulates the SWD magnitude and WT behavior.

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43

Hamani, Clement, Sumire Sakabe, Zuner A. Bortolotto, Esper A. Cavalheiro, and Luiz E. A. M. Mello. "Inhibitory role of the zona incerta in the pilocarpine model of epilepsy." Epilepsy Research 49, no. 1 (March 2002): 73–80. http://dx.doi.org/10.1016/s0920-1211(02)00017-7.

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44

Bagi, Éva Eszter, Éva Fekete, and László Lénárd. "Angiotensin II and III microinjections into the zona incerta influence drinking behavior." Brain Research 977, no. 2 (July 2003): 199–208. http://dx.doi.org/10.1016/s0006-8993(03)02680-5.

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45

Diamond, Mathew E., and Ehud Ahissar. "When Outgoing and Incoming Signals Meet: New Insights from the Zona Incerta." Neuron 56, no. 4 (November 2007): 578–79. http://dx.doi.org/10.1016/j.neuron.2007.11.006.

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46

Lau, Jonathan C., Yiming Xiao, Roy A. M. Haast, Greydon Gilmore, Kâmil Uludağ, Keith W. MacDougall, Ravi S. Menon, Andrew G. Parrent, Terry M. Peters, and Ali R. Khan. "Direct visualization and characterization of the human zona incerta and surrounding structures." Human Brain Mapping 41, no. 16 (July 17, 2020): 4500–4517. http://dx.doi.org/10.1002/hbm.25137.

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47

Mitrofanis, John, and Lilijana Mikuletic. "Organisation of the cortical projection to the zona incerta of the thalamus." Journal of Comparative Neurology 412, no. 1 (September 13, 1999): 173–85. http://dx.doi.org/10.1002/(sici)1096-9861(19990913)412:1<173::aid-cne13>3.0.co;2-q.

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48

Kim, Uhnoh, E. Gregory, and William C. Hall. "Pathway from the zona incerta to the superior colliculus in the rat." Journal of Comparative Neurology 321, no. 4 (July 22, 1992): 555–75. http://dx.doi.org/10.1002/cne.903210405.

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49

Ma, Terence P., James C. Johnson, and Glenn A. Hoskins. "Organization of the zona incerta in the macaque: An electron microscopic study." Anatomical Record 249, no. 2 (October 1997): 259–75. http://dx.doi.org/10.1002/(sici)1097-0185(199710)249:2<259::aid-ar14>3.0.co;2-n.

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50

Kerl, H. U., L. Gerigk, S. Huck, M. Al-Zghloul, C. Groden, and I. S. Nölte. "Visualisation of the Zona Incerta for Deep Brain Stimulation at 3.0 Tesla." Clinical Neuroradiology 22, no. 1 (February 17, 2012): 55–68. http://dx.doi.org/10.1007/s00062-012-0136-3.

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