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Dissertations / Theses on the topic 'Zona pellucida'

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1

Koothan, Thillai. "Structural and functional analysis of zona pellucida." Thesis, University of Edinburgh, 1994. http://hdl.handle.net/1842/19905.

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The ability of the zona pellucida to mediate the species specific recognition of spermatozoa is due to a glycoprotein constituent of this structure, known as ZP3. In view of its important role in the initiation of fertilization, ZP3 has been identified as a suitable candidate for the development of a contraceptive vaccine. In order to generate recombinant marmoset ZP3 for immunization purposes a full length 1.3 kb insert encoding for marmoset ZP3 was cloned downstream of the malE gene to generate a fusion protein containing marZP3 and a maltose binding domain. This protein was found to be gene
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2

Chapman, Jamie. "The marsupial zona pellucida : its structure and glycoconjugate content." Title page, abstract and contents only, 2003. http://web4.library.adelaide.edu.au/theses/09PH/09phc4661.pdf.

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Bibliography: leaves 262-298. This thesis investigated the structure and glycoconjugate composition of the zona pellucida (ZP) surrounding marsupial oocytes and the changes that occur during ovarian development, following ovulation, and following cortical granule exocytosis. The glycoconjugates of the oviduct epithelial lining of the brushtail possum around the time of ovulation were also examined to determine if there was any contribution of the oviductal secretions to the post-ovulatory ZP.
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3

Gaboriau, David Claude Andre. "Binding of boar sperm proacrosin to the zona pellucida." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613079.

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4

Chung, Man-kin, and 鍾文健. "Biological characterization of cumulus glycodelin on humanspermatozoa-zona pellucida interaction." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42182633.

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5

Lacey, Helen Ann. "Production and characterisation of recombinant human zona pellucida glycoprotein 2." Thesis, University of Sheffield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322910.

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6

Ringleb, Jennifer. "Identifikation antigener Determinanten des ZPB2-Proteins der Hauskatze und Charakterisierung ihrer kontrazeptiven und immunogenen Eigenschaften." Phd thesis, [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=974115282.

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7

Witzendorff, Dorothee von. "Das Glykom und Proteom der porcinen Zona pellucida ein massenspektrometrischer Ansatz /." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=981929931.

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8

Pfisterer, Susanne Charlotte Martha. "Herstellung, Charakterisierung und Einsatz von anti-Zona pellucida Protein 3 Peptidantiseren." [S.l.] : [s.n.], 1999. http://deposit.ddb.de/cgi-bin/dokserv?idn=958759006.

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9

Chung, Man-kin. "Biological characterization of cumulus glycodelin on human spermatozoa-zona pellucida interaction." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42182633.

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10

Törmälä, R. M. (Reeta-Maria). "Human zona pellucida abnormalities:a genetic approach to the understanding of fertilization failure." Doctoral thesis, Oulun yliopisto, 2016. http://urn.fi/urn:isbn:9789526212982.

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Abstract Despite the development of assisted reproduction technologies and significant advances in reproductive biology and medicine over the years the cause of infertility remains unexplained in 10–20% of cases. The cause of infertility in these cases may be connected to problems in fertilization or implantation and genetic factors may play a part in this. The zona pellucida (ZP) is an extracellular matrix surrounding the oocyte and early-stage embryos. It is important for folliculogenesis, fertilization and implantation. In humans, it is composed of four known ZP glycoproteins that all show
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11

Hägele, Wolfgang. "Herstellung, Charakterisierung und Einsatz von Anti-Zona pellucida-Protein 2-Peptid-Antiseren." [S.l.] : [s.n.], 1998. http://bibd.uni-giessen.de/gdoc/1998/uni/D980008.PS.

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12

Balbach, Melanie [Verfasser]. "Action of zona pellucida glycoproteins in mouse and human sperm / Melanie Balbach." Bonn : Universitäts- und Landesbibliothek Bonn, 2017. http://d-nb.info/1166754790/34.

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13

Bastiaan, Hadley Saville. "The effect of solubilized homologous zona pellucida on the human acrosome reaction, sperm-zona binding and motion characteristics of capacitated human spermatozoa." Thesis, Stellenbosch : Stellenbosch University, 2003. http://hdl.handle.net/10019.1/53630.

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Thesis (PhD)--Stellenbosch University, 2003.<br>ENGLISH ABSTRACT: CHAPTER 1 provides literature based background information to emphasize the use of a sequential, multistep diagnostic schedule for couples in an assisted reproductive program as well as the clinical importance of sperm morphology as recorded by strict criteria during the diagnostic approach of the infertile couple. Furthermore, the chapter includes evidence underlining the growing need for the implementation of the physiologically induced acrosome reaction as an important contribution to the assisted reproductive program.
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14

Lowe, Jeanette. "Phage Display to Identify Peptides Binding to or Penetrating the Mouse Zona Pellucida." Thesis, Virginia Tech, 1999. http://hdl.handle.net/10919/35902.

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The objective of this study was to identify peptide ligands, using phage display techniques, which bind sites on mouse embryos, ovaries, cytoplasmic membranes and/or intracytoplasmic components. Specifically, M13 coliphage 7-mer, 12-mer and 15-mer random peptide libraries were used separately for biopanning. Peptides derived from the amplified pools were sequenced and studied. The phage display for in vivo ovary experiments yielded no pool of peptides after two cycles of biopanning and re-amplification. With the same initial concentration of a random 7-mer or 12-mer library, there were rep
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15

Lunn, Matthew O'Brien. "A Morphological Study of the Canine Zona Pellucida: A Heterogeneous Ultrastructure and Barrier." University of Dayton / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1311785290.

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16

au, joyceand@iinet net, and Jocye A. Eade. "Investigating porcine and feline zona pellucida as immunocontraceptive antigens in the female domestic cat." Murdoch University, 2007. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20070717.124229.

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Immunocontraception, or contraception mediated by the immune system, is being widely studied as an alternative, humane form of population control. The induction of an immune response against a specific component of the mammalian oocyte, termed zona pellucida (ZP) has been shown to be an effective immunocontraceptive in several species. Comparatively little work has been done investigating the use of ZP antigens in the domestic cat. This study aimed to investigate porcine ZP(B+C) and feline ZPA, B and C as immunogens in the domestic cat, and further to elucidate their effects on reproduction. I
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17

Eade, Joyce A. "Investigating porcine and feline zona pellucida as immunocontraceptive antigens in the female domestic cat /." Access via Murdoch University Digital Theses Project, 2007. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20070717.124229.

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18

Wong, Siu-tak, and 黃兆德. "Priming effect of glycodelin-A on zona pellucida induced acrosome reaction in human spermatozoa." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41508439.

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19

Wong, Siu-tak. "Priming effect of glycodelin-A on zona pellucida induced acrosome reaction in human spermatozoa." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41508439.

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20

Eade, Jocye A. "Investigating porcine and feline zona pellucida as immunocontraceptive antigens in the female domestic cat." Thesis, Eade, Jocye A. (2007) Investigating porcine and feline zona pellucida as immunocontraceptive antigens in the female domestic cat. PhD thesis, Murdoch University, 2007. https://researchrepository.murdoch.edu.au/id/eprint/59/.

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Immunocontraception, or contraception mediated by the immune system, is being widely studied as an alternative, humane form of population control. The induction of an immune response against a specific component of the mammalian oocyte, termed zona pellucida (ZP) has been shown to be an effective immunocontraceptive in several species. Comparatively little work has been done investigating the use of ZP antigens in the domestic cat. This study aimed to investigate porcine ZP(B+C) and feline ZPA, B and C as immunogens in the domestic cat, and further to elucidate their effects on reproduction. I
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21

Eade, Jocye A. "Investigating porcine and feline zona pellucida as immunocontraceptive antigens in the female domestic cat." Eade, Jocye A. (2007) Investigating porcine and feline zona pellucida as immunocontraceptive antigens in the female domestic cat. PhD thesis, Murdoch University, 2007. http://researchrepository.murdoch.edu.au/59/.

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Immunocontraception, or contraception mediated by the immune system, is being widely studied as an alternative, humane form of population control. The induction of an immune response against a specific component of the mammalian oocyte, termed zona pellucida (ZP) has been shown to be an effective immunocontraceptive in several species. Comparatively little work has been done investigating the use of ZP antigens in the domestic cat. This study aimed to investigate porcine ZP(B+C) and feline ZPA, B and C as immunogens in the domestic cat, and further to elucidate their effects on reproduction. I
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22

Bates, Melodie Joy. "Endocrine correlates of free-ranging African elephant (Loxodonta africana) treated with porcine zona pellucida vaccine." Diss., University of Pretoria, 2010. http://hdl.handle.net/2263/25181.

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Due to overpopulation of African elephants in South Africa and the consequent threat to biodiversity, the need for a method of population control has become evident. The potential use of the porcine zona pellucida (pZP) vaccine as a safe and effective means for population control is explored. While potential effects of pZP treatment on social behaviour of African elephants have been investigated, no examination of the influence of pZP vaccination on the endocrine correlates in treated females has been undertaken. The ovarian activity of freeranging, pZP-treated African elephant females was mon
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23

Oehninger, Sergio C. "The interaction between human spermatozoa and its homologous zona pellucida : scientific advances and clinical significance." Thesis, Stellenbosch : Stellenbosch University, 2002. http://hdl.handle.net/10019.1/53132.

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Thesis (PhD)--Stellenbosch University, 2002.<br>ENGLISH ABSTRACT: Infertility is a very common problem worldwide. Recent data have shown that disorders of the male represent the most common single defined cause of infertility. This proposal examines the clinical significance and fundamental physiological aspects of human gamete interaction. These studies are focused on the assessment of the cellular-molecular mechanisms involved in human sperm binding to its homologous zona pellucida resulting in the physiologic induction of the acrosome reaction. We have developed and validated in vitro
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24

Kuske, Michael [Verfasser]. "Das Zusammenspiel der Proteasen Akrosin und Ovastacin bei der Härtung der Zona pellucida / Michael Kuske." Mainz : Universitätsbibliothek der Johannes Gutenberg-Universität Mainz, 2021. http://d-nb.info/1231433469/34.

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25

Kaskar, Khalied. "Evaluation of quantitative motility and zona pellucida binding of human spermatozoa in an assisted reproductive programme." University of the Western Cape, 1994. http://hdl.handle.net/11394/8416.

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>Magister Scientiae - MSc<br>Male factor disorders affect more than 30% of infertile couples. Thus, it has become important to perform a andrological consultation and a basic semen evaluation in all male partners of couples consulting for infertility. The advent and development of assisted reproductive technologies has not only improved clinical results but also enhanced our basic understanding of the physiology of sperm and sperm preparation methods. Assisted reproduction has become among the more successful therapeutic modalities for a wide variety of sperm function disorders e.g. artificial
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26

Levy, Maria Patricia Morales. "Development of a DNA vaccine for population control : a zona pellucida based nucleic acid vaccine (ZP-NAV) /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2005. http://uclibs.org/PID/11984.

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27

Shahror, Rami Ahmad Nawaf. "Characterization of the Transcription Factor NF‐Y in the Regulation of Zona Pellucida Genes in Zebrafish Ovary." Thesis, Örebro universitet, Institutionen för naturvetenskap och teknik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-30318.

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Zona pellucida glycoproteins (ZP) are important proteins for maturation of the oocytes in eukaryotes, these proteins are encoded by cluster of zp genes. zp2.3 and zp3.5 genes are expressed during the developing and maturation of the oocytes in zebrafish ovaries. Both of the gens have a CCAAT box in their promoter regions, playing a big role in the expression of the both genes in zebrafish oocytes. The transcription of the genes in the eukaryotes requires transcription factors to initiate and promote the transcription, the transcription factors can bind to the promoter region and initiate the t
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28

Petersen, Claudia Guilhermino. "Correlação da maturação e da morfologia do oócito humano com as características do fuso meiótico e da zona pelúcida /." Botucatu : [s.n.], 2009. http://hdl.handle.net/11449/106388.

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Orientador: José Gonçalves Franco Júnior<br>Banca: Anice Maria Vieira Camargo Martins<br>Banca: Edson Borges<br>Banca: Jorge Nahas Filho<br>Banca: Ana Lúcia Kalinin<br>Resumo: Nas últimas décadas, alguns parâmetros laboratoriais têm sido propostos para identificar o potencial de saúde oocitária em Reprodução Assistida: 1. Maturidade nuclear e citoplasmática (pesquisa); 2. Dismorfismo (anomalias intracitoplasmáticas); 3. Fertilizaçao. Habitualmente, esses parâmetros (exceto a maturação citoplasmática) são avaliados pelo simples emprego de sistemas de microscopia de luz convencional. Nos últimos
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29

Gan, Yong Chen Zhen. "Model-based simulations of the piercing process in piezo-ICSI." Diss., Columbia, Mo. : University of Missouri--Columbia, 2008. http://hdl.handle.net/10355/7111.

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Title from PDF of title page (University of Missouri--Columbia, viewed on Feb. 23, 2010 ). The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. Dr. Zhen Chen, Dissertation Supervisor. Vita. Includes bibliographical references.
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30

Parkinson, Christine Anne. "Cloning and characterisation of a zebrafish cDNA encoding a novel member of the Zona pellucida family of proteins." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271294.

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31

Du, Plessis S. S. (Simon Stephanus). "A study of the intracellular signalling events involved in the zona pellucida-induced acrosome reaction in human spermatozoa." Thesis, Stellenbosch : Stellenbosch University, 2002. http://hdl.handle.net/10019.1/52709.

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Thesis (PhD)--Stellenbosch University, 2002.<br>ENGLISH ABSTRACT: In this study the author presents new data that will shed light on the fairly nebulous knowledge of intracellular pathways involved in the physiologically induced acrosome reaction and the subsequent events leading to fertilization. The zona pellucidainduced acrosome reaction, sperm-zona interaction as well as various sperm motion characteristics were investigated. The first part of the study focussed on the role of extracellular signal regulated kinase (ERK), a member of the family of mitogen activated protein kinases, d
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32

Fernandes, Isabelle. "Etude fonctionnelle des protéines à domaine Zona Pellucida au cours de la morphogenèse épidermique embryonnaire chez la Drosophile." Toulouse 3, 2009. http://thesesups.ups-tlse.fr/767/.

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Le domaine Zona Pellucida (ZP) définit une famille de protéines membranaires conservées au cours de l'évolution. Cependant le rôle de ces protéines au cours du développement reste encore mal caractérisé. Par une approche génétique chez la drosophile, nous montrons qu'un ensemble de huit protéines ZPD est nécessaire à la réorganisation localisée du compartiment apical au cours de la morphogenèse épidermique embryonnaire. Malgré la conservation structurale des domaines ZP, ces protéines possèdent des fonctions spécifiques dans le remodelage de la forme apicale des cellules épidermiques. En effet
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33

Dietzel, Eileen [Verfasser]. "The biological role of fetuin-B : inhibition of zona pellucida hardening and preservation of female fertility in mice / Eileen Dietzel." Aachen : Hochschulbibliothek der Rheinisch-Westfälischen Technischen Hochschule Aachen, 2015. http://d-nb.info/1066813701/34.

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34

Ström, Holst Bodil. "In vitro characterisation of cryopreserved canine spermatozoa : with special reference to post-thaw survival time and zona pellucida binding capacity /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1999. http://epsilon.slu.se/avh/1999/91-576-5445-X.pdf.

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35

Petersen, Claudia Guilhermino [UNESP]. "Correlação da maturação e da morfologia do oócito humano com as características do fuso meiótico e da zona pelúcida." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/106388.

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Made available in DSpace on 2014-06-11T19:35:39Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-02-17Bitstream added on 2014-06-13T19:05:47Z : No. of bitstreams: 1 costa_cgpr_dr_botfm.pdf: 1744933 bytes, checksum: d90abe2ebd4b5e05246936b2f56031cd (MD5)<br>Nas últimas décadas, alguns parâmetros laboratoriais têm sido propostos para identificar o potencial de saúde oocitária em Reprodução Assistida: 1. Maturidade nuclear e citoplasmática (pesquisa); 2. Dismorfismo (anomalias intracitoplasmáticas); 3. Fertilizaçao. Habitualmente, esses parâmetros (exceto a maturação citoplasmática) são a
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36

Safatli, Micheline. "Synthesis of neutral and acidic ß-O-linked glycoconjugates related to those found in the core structure of mammalian zona pellucida." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ36522.pdf.

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37

Grullón, Yunén Luis Alberto. "Función del sistema plasminógeno-plasmina en la fecundación de ovocitos bovinos y porcinos." Doctoral thesis, Universidad de Murcia, 2010. http://hdl.handle.net/10803/32113.

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El objetivo de este trabajo consistió en describir el papel del sistema plasminógeno/plasmina (PLG/PLA) en la fecundación bovina y porcina. Mediante fecundación in vitro, demostramos que la presencia de PLG ó PLA en el medio de coincubación de los gametos disminuía la penetración de los espermatozoides en los ovocitos y su unión a la zona pelúcida (ZP). Esta disminución no se debía a alteraciones de la funcionalidad espermática ni a cambios en la resistencia de la ZP a la proteolisis, sino a que la PLA provocaba la liberación de los espermatozoides adheridos a la ZP. Mediante inmunofluorescenc
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38

El-Mestrah, Majid Fouad. "Zona pellucida glycoproteins, structural topography and modifications of the carbohydrate determinants during folliculogenesis and following in vivo fertilization and in vitro egg activation." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/NQ59525.pdf.

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39

Hermansson, Ulrika. "Studies of canine and feline sperm viability under different storage procedures : with special reference to chilling, freezing, and use of zona pellucida binding assays /." Uppsala : Department of Clinical Sciences, Swedish University of Agricultural Sciences, 2006. http://epsilon.slu.se/200668.pdf.

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40

Hanna, William F. "Sperm-zona pellucida interactions in the mouse evidence that Lewis X-containing neoglycoproteins mimic the intrinsic ability of ZP3 to induce the acrosome reaction /." Available to US Hopkins community, 2002. http://wwwlib.umi.com/dissertations/dlnow/3068781.

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Saucedo, Manuel Nicolas Verfasser], and Eckhard [Akademischer Betreuer] [Wolf. "Comparison between two vitrification methods for in vitro produced bovine embryos with an intact or a nonintact zona pellucida / Manuel Nicolas Saucedo. Betreuer: Eckhard Wolf." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2016. http://d-nb.info/1102157201/34.

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42

Bou, Khalil Maroun. "Biophysical and biochemical properties of the mammalian male germ cell specific sulfogalactosylglycerolipid (SGG): Contribution to the structure and zona pellucida affinity of pig sperm raft membranes." Thesis, University of Ottawa (Canada), 2004. http://hdl.handle.net/10393/29079.

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Raft membranes are implicated in cell adhesion. Here, we demonstrated that rafts isolated from hypermotile capacitated pig sperm as low-density Triton X-100 insoluble membranes had the ability to bind specifically to homologous zonae pellucidae (ZP). This binding was dependent on pig ZP3alpha sulfoglycoprotein, a major player in intact sperm binding. The male germ cell specific sulfogalactosylglycerolipid (SGG) was a sperm raft component and participated in sperm raft-ZP binding, since rafts pretreated with anti-SGG IgG/Fab had decreased ability to bind to the ZP dose dependently. SGG may also
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43

Zhang, Bing Rong. "Evaluation of frozen-thawed semen from Swedish Red and White AI bulls : with special reference to the relation between zona pellucida binding, in vitro fertilization and in vivo fertility /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1998. http://epsilon.slu.se/avh/1998/91-576-5436-0.gif.

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44

Bulgarelli, Daiane Lopes. "A vitrificação de oócitos bovinos prejudica sua capacidade reprodutiva, independente do estadio de maturação." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/17/17145/tde-10012017-115656/.

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Até o momento a literatura não determinou qual o melhor estadio de maturação (imaturo ou maduro) para que o oocito mantenha sua competência para o desenvolvimento reprodutivo após a criopreservação. O objetivo deste estudo foi determinar em qual estadio meiótico (imaturo -VG (vesícula germinativa) ou maduro- MII (metáfase II)) o oócito é menos susceptível ao dano na criopreservação, utilizando modelo experimental bovino. Foram utilizados ovários de vacas abatidas em matadouro, após a aspiração dos folículos, os oócitos imaturos (VG) foram selecionados para a maturação in vitro e vitrificação,
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Cánovas, Bernabé Sebastián. "Interacciones homólogas y heterólogas in vitro de gametos porcinos, bovinos y humanos y sus aplicaciones en el estudio de la fecundación." Doctoral thesis, Universidad de Murcia, 2007. http://hdl.handle.net/10803/10851.

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La interacción entre gametos es crucial para la fecundación. La zona pelúcida (ZP) se considera responsable de bloquear la polispermia, pero in vitro estas funciones no son totalmente eficientes. La polispermia es frecuente en fecundación in vitro (FIV) en porcino y bovino, mientras que la interacción heteróloga espermatozoide-ovocito ha sido demostrada. Los objetivos fueron estudiar el bloqueo de la polispermia para mejorar los resultados de FIV e investigar las interacciones heterólogas entre espermatozoide humano y ovocito porcino. Los resultados demuestran que se produce endurecimiento d
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Kongmanas, Kessiri. "Roles of Seminolipid and Its Associated Membrane Domain in Male Fertility." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32509.

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Our research aims at understanding the roles of seminolipid (sulfogalactosylglycerolipid or SGG) and its associated membrane domains in male reproduction. SGG is a sulfoglycolipid present selectively and abundantly in mammalian male germ cells. Therefore, information on its properties would be relevant towards the development of male fertility biomarkers and spermicide-based contraceptives. We have shown that SGG has direct affinity for zona pellucida (ZP, egg extracellular matrix) and plays a role in the formation of sperm lipid rafts, the ZP-binding platforms on the sperm anterior head pl
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Mazzeo, Ilaria. "Effect of thermal regime on the expression of key reproductive genes during hormonally-induced vitellogenesis in female European eels." Doctoral thesis, Universitat Politècnica de València, 2015. http://hdl.handle.net/10251/48490.

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European eel (Anguilla anguilla, L., 1758) is suffering a strong population decrease and at the same time it is a very appreciated species and by now it has not been possible closing its cycle life. In fact, this species does not mature in captivity unless hormonally induced. So all the production is up to the natural population. All these factors together make urgent achieving the closing of the productive cycle and for this aim it is important to understand the reproductive physiology and the reasons of this development blockage. The present thesis wants to be a new contribution to
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48

Busca, Cláudia Sofia Nunes. "Analysis of the role of ZP3 and APP in cell-cell adhesion." Master's thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/12945.

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Mestrado em Biomedicina Molecula<br>Among different types of cell-cell interactions present in the body, the interaction between the oocyte and a sperm cell is of great importance for species perpetuation. Cellular adhesion is thus a crucial process in fertilization, which involves the oocyte’s zona pellucida (ZP), the first barrier found by sperm cells that mediates the first contact between gametes. ZP3 is a major ZP glycoprotein of the oocyte, and its ligand in sperm cells is still unknown. The APP glycoprotein was found by us to be in the sperm’s head, including its equatorial zone involve
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49

LUCAS, HERVE. "La zone pellucide : etude des oligosaccharides dans deux especes animales et chez l'homme." Angers, 1993. http://www.theses.fr/1993ANGE1130.

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Bercegeay, Sylvain. "Contribution a l'etude de la zone pellucide de l'ovocyte : composition et modification au cours du processus de fecondation." Nantes, 1995. http://www.theses.fr/1995NANT01VS.

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