Academic literature on the topic 'Zoom ADCs'

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Journal articles on the topic "Zoom ADCs"

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Kim, Lily H., Edward H. Lee, Michelle Galvez, et al. "Reduced field of view echo-planar imaging diffusion tensor MRI for pediatric spinal tumors." Journal of Neurosurgery: Spine 31, no. 4 (2019): 607–15. http://dx.doi.org/10.3171/2019.4.spine19178.

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OBJECTIVESpine MRI is a diagnostic modality for evaluating pediatric CNS tumors. Applying diffusion-weighted MRI (DWI) or diffusion tensor imaging (DTI) to the spine poses challenges due to intrinsic spinal anatomy that exacerbates various image-related artifacts, such as signal dropouts or pileups, geometrical distortions, and incomplete fat suppression. The zonal oblique multislice (ZOOM)–echo-planar imaging (EPI) technique reduces geometric distortion and image blurring by reducing the field of view (FOV) without signal aliasing into the FOV. The authors hypothesized that the ZOOM-EPI method for spine DTI in concert with conventional spinal MRI is an efficient method for augmenting the evaluation of pediatric spinal tumors.METHODSThirty-eight consecutive patients (mean age 8 years) who underwent ZOOM-EPI spine DTI for CNS tumor workup were retrospectively identified. Patients underwent conventional spine MRI and ZOOM-EPI DTI spine MRI. Two blinded radiologists independently reviewed two sets of randomized images: conventional spine MRI without ZOOM-EPI DTI, and conventional spine MRI with ZOOM-EPI DTI. For both image sets, the reviewers scored the findings based on lesion conspicuity and diagnostic confidence using a 5-point Likert scale. The reviewers also recorded presence of tumors. Quantitative apparent diffusion coefficient (ADC) measurements of various spinal tumors were extracted. Tractography was performed in a subset of patients undergoing presurgical evaluation.RESULTSSixteen patients demonstrated spinal tumor lesions. The readers were in moderate agreement (kappa = 0.61, 95% CI 0.30–0.91). The mean scores for conventional MRI and combined conventional MRI and DTI were as follows, respectively: 3.0 and 4.0 for lesion conspicuity (p = 0.0039), and 2.8 and 3.9 for diagnostic confidence (p < 0.001). ZOOM-EPI DTI identified new lesions in 3 patients. In 3 patients, tractography used for neurosurgical planning showed characteristic fiber tract projections. The mean weighted ADCs of low- and high-grade tumors were 1201 × 10−6 and 865 × 10−6 mm2/sec (p = 0.002), respectively; the mean minimum weighted ADCs were 823 × 10−6 and 474 × 10−6 mm2/sec (p = 0.0003), respectively.CONCLUSIONSDiffusion MRI with ZOOM-EPI can improve the detection of spinal lesions while providing quantitative diffusion information that helps distinguish low- from high-grade tumors. By adding a 2-minute DTI scan, quantitative diffusion information and tract profiles can reliably be obtained and serve as a useful adjunct to presurgical planning for pediatric spinal tumors.
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Xie, Shuang, and Albert J. P. Theuwissen. "A CMOS Image Sensor With Thermal Sensing Capability and Column Zoom ADCs." IEEE Sensors Journal 20, no. 5 (2020): 2398–404. http://dx.doi.org/10.1109/jsen.2019.2954082.

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Merino, Aimee, Phillip Dougherty, Bin Zhang, J. P. Houchins, Jeffrey S. Miller, and Frank Cichocki. "Adaptive NK Cells Are Expanded By NKG2C-Agonist Antibodies and Retain Their Cytotoxic and Secretory Properties." Blood 132, Supplement 1 (2018): 3695. http://dx.doi.org/10.1182/blood-2018-99-113669.

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Abstract Natural killer (NK) cells can eliminate myeloid leukemia cells after stem cell transplant, yet many patients relapse. Several reports have described significant decreases in relapse rates post-transplant in recipients that experienced cytomegalovirus (CMV) reactivation. Our group has shown that reduced relapse rates correlated with expansion of adaptive NK cells, which can be defined by surface expression of the maturation marker CD57 and the activating receptor NKG2C. Adaptive NK cells live longer, are more resistant to immune suppression than canonical NK cells, exhibit properties of immune memory, and their presence in peripheral blood is only observed in CMV seropositive individuals. Given the in vitro and in vivo evidence for enhanced function of adaptive NK cells against malignant cells, we sought to develop a method to preferentially expand this subset in vitro. To this end, we stimulated NK cells isolated from the peripheral blood of healthy CMV seropositive donors for 7 days with IL-15 and either a plate-bound control IgG isotype antibody or an antibody that was determined to be a strong agonist of NKG2C signaling in redirected antibody-dependent cellular cytotoxicity (ADCC) assays. We observed robust proliferation of NKG2C+ NK cells when stimulated with the anti-NKG2C agonist antibody (Figure 1A). High proliferation rates were accompanied by significant induction of the checkpoint inhibitory receptors programmed death-1 (PD-1) and lymphocyte activation gene-3 (LAG-3) (Figure 1B), with LAG-3 expression nearly doubling on NKG2C+ NK cells. LAG-3 is a unique checkpoint inhibitor that ligates MHC class II molecules and is highly expressed on lymphocytes in patients with various types of malignancy. The stimulated NK cells were also highly active, as evidenced by a complete switch from a CD45RA+CD45RO- to CD45RA-CD45RO+ phenotype (Figure 1C). CD45ROexpression on lymphocytes has been associated with better prognosis in solid tumors including melanoma, lung, and endometrial cancers suggesting a potent ability to target malignant cells. Despite the increased expression of checkpoint inhibitory receptors, expanded NKG2C+ NK cells remained highly functional. In assays where NK cells were used as effectors against K562 cells, (a myeloid leukemia cell line), we found that NKG2C agonist antibody-expanded NK cells exhibited higher frequencies of tumor necrosis factor (TNF) and interferon (IFN)-γ production compared to NK cells from control IgG isotype cultures. Surprisingly, we found that NK cells expressing LAG-3, instead of exhibiting functional exhaustion, were highly responsive to tumor targets (Figure 1D). To directly test the cytotoxic function of adaptive NK cells expanded with the anti-NKG2C antibody, we analyzed NK cell-mediated killing of dye-labeled K562 cells over the course of 48 hours by live imaging using an IncuCyte Zoom instrument. We observed more rapid killing kinetics and more robust overall target cell killing by adaptive NK cells expanded with the anti-NKG2C agonist antibody relative to the IgG isotype control condition (Figure 1E). Our data show that CD57+NKG2C+, adaptive NK cells can be efficiently expanded using NKG2C-agonist antibodies. These cells exhibit potent killing abilities and enhanced cytokine secretion, making them ideal candidates for adoptive cell transfer in hematologic malignancies. We also show that LAG-3, a checkpoint inhibitory receptor, is actually associated with enhanced NK cell function in these in vitro assays. This is likely because of the relatively short period of activation (7 days) to which the NK cells are exposed during expansion. There are at least four LAG-3 targeted therapies currently in clinical trials with more in development. A better understanding of the mechanisms of expression of this important receptor and its impact on NK cell function will aid in the rational use of checkpoint inhibitory receptor therapies for cancer patients. Disclosures Houchins: Bio-Techne Inc: Employment. Cichocki:Fate Therapeutics Inc.: Consultancy, Research Funding.
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Dissertations / Theses on the topic "Zoom ADCs"

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"Passive Loop Filter Zoom Analog to Digital Converters." Doctoral diss., 2018. http://hdl.handle.net/2286/R.I.51619.

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abstract: This dissertation proposes and presents two different passive sigma-delta modulator zoom Analog to Digital Converter (ADC) architectures. The first ADC is fullydifferential, synthesizable zoom-ADC architecture with a passive loop filter for lowfrequency Built in Self-Test (BIST) applications. The detailed ADC architecture and a step by step process designing the zoom-ADC along with a synthesis tool that can target various design specifications are presented. The design flow does not rely on extensive knowledge of an experienced ADC designer. Two example set of BIST ADCs have been synthesized with different performance requirements in 65nm CMOS process. The first ADC achieves 90.4dB Signal to Noise Ratio (SNR) in 512µs measurement time and consumes 17µW power. Another example achieves 78.2dB SNR in 31.25µs measurement time and consumes 63µW power. The second ADC architecture is a multi-mode, dynamically zooming passive sigma-delta modulator. The architecture is based on a 5b interpolating flash ADC as the zooming unit, and a passive discrete time sigma delta modulator as the fine conversion unit. The proposed ADC provides an Oversampling Ratio (OSR)- independent, dynamic zooming technique, employing an interpolating zooming front-end. The modulator covers between 0.1 MHz and 10 MHz signal bandwidth which makes it suitable for cellular applications including 4G radio systems. By reconfiguring the OSR, bias current, and component parameters, optimal power consumption can be achieved for every mode. The ADC is implemented in 0.13 µm CMOS technology and it achieves an SNDR of 82.2/77.1/74.2/68 dB for 0.1/1.92/5/10MHz bandwidth with 1.3/5.7/9.6/11.9mW power consumption from a 1.2 V supply.<br>Dissertation/Thesis<br>Doctoral Dissertation Electrical Engineering 2018
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Book chapters on the topic "Zoom ADCs"

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Gönen, Burak, Fabio Sebastiano, Robert van Veldhoven, and Kofi A. A. Makinwa. "A Hybrid ADC for High Resolution: The Zoom ADC." In Hybrid ADCs, Smart Sensors for the IoT, and Sub-1V & Advanced Node Analog Circuit Design. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-61285-0_6.

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Unnisa, Rafath, and P. Trinatha Rao. "Efficient Integration of Zoom ADC with Temperature Sensors for System on Chip Applications—A Perspective." In Lecture Notes in Electrical Engineering. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-7329-8_32.

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Venkata, Manoj Katta, and Veeresh Babu Vulligaddala. "An 18-Bit Incremental Zoom ADC with Reduced Delay Overhead Data Weighted Averaging for Battery Measurement Systems." In Lecture Notes in Electrical Engineering. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-33-4058-9_15.

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Müller, Viola Franziska. "Illegal but Tolerated." In Fugitive Slaves and Spaces of Freedom in North America. University Press of Florida, 2018. http://dx.doi.org/10.5744/florida/9780813056036.003.0007.

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As antebellum Virginia became the main point of departure for the domestic slave trade and enslaved people increasingly ran the risk of being sold and deported to the Deep South, the free black population of Richmond, Virginia, was substantially augmented by an influx of fugitive slaves from the surrounding countryside who attempted to escape slavery by illegally passing themselves off as free. At the same time, the city became an important industrial site, stimulating an incessant demand for factory workers (both men and women) and domestic servants in the households of the growing white merchant class, thereby significantly expanding employment opportunities for black residents. These developments provided opportunities for slave refugees to hide amongst the free black population, pass for free, and find work in the booming labor markets of the city. Following up on the previous chapter, this chapter zooms in on a specific case study and focuses on the residential and economic integration of slave refugees in the Antebellum South, the interdependence of free blacks and fugitive slaves, and the intermingling of the lower classes within the bustling urban environment of Virginia’s capital city. Drawing from police registers, runaway slave ads, and court documents—all of which reveal illuminating details about the lives of runaway slaves and their interactions with the free black population—it reveals how fugitive slaves navigated an informal freedom in ways similar to the migration experiences of today’s illegal immigrants.
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Conference papers on the topic "Zoom ADCs"

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Xie, Shuang, Xiaoliang Ge, and Albert Theuwissen. "Temperature Sensors Incorporated into a CMOS Image Sensor with Column Zoom ADCs." In 2019 IEEE International Symposium on Circuits and Systems (ISCAS). IEEE, 2019. http://dx.doi.org/10.1109/iscas.2019.8702321.

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O'Leary, Gerard, M. Reza Pazhouhandeh, Michael Chang та ін. "A recursive-memory brain-state classifier with 32-channel track-and-zoom Δ2 Σ ADCs and Charge-Balanced Programmable Waveform Neurostimulators". У 2018 IEEE International Solid-State Circuits Conference (ISSCC). IEEE, 2018. http://dx.doi.org/10.1109/isscc.2018.8310301.

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Seo, Ki-Hoon, Il-Hoon Jang, Kyung-Jun Noh, and Seung-Tak Ryu. "An incremental zoom sturdy MASH ADC." In 2017 IEEE 60th International Midwest Symposium on Circuits and Systems (MWSCAS). IEEE, 2017. http://dx.doi.org/10.1109/mwscas.2017.8053098.

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Gonen, Burak, Shoubhik Karmakar, Robert van Veldhoven, and Kofi Makinwa. "A Low Power Continuous-Time Zoom ADC for Audio Applications." In 2019 Symposium on VLSI Circuits. IEEE, 2019. http://dx.doi.org/10.23919/vlsic.2019.8778021.

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Gao, Jie, Chongfei Shen, Baodong Yu, Hongyun Xie, Zhijie Chen, and Peiyuan Wan. "Simulink Modeling and Performance Verification of a High Resolution Zoom ADC." In 2019 IEEE 13th International Conference on Anti-counterfeiting, Security, and Identification (ASID). IEEE, 2019. http://dx.doi.org/10.1109/icasid.2019.8925296.

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Gonen, Burak, Fabio Sebastiano, Robert van Veldhoven, and Kofi A. A. Makinwa. "A 1.65mW 0.16mm2 dynamic zoom-ADC with 107.5dB DR in 20kHz BW." In 2016 IEEE International Solid-State Circuits Conference (ISSCC). IEEE, 2016. http://dx.doi.org/10.1109/isscc.2016.7418017.

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Eland, Efraim, Shoubhik Karmakar, Burak Gonen, Robert van Veldhoven та Kofi Makinwa. "A 440μW, 109.8dB DR, 106.5dB SNDR Discrete-Time Zoom ADC with a 20kHz BW". У 2020 IEEE Symposium on VLSI Circuits. IEEE, 2020. http://dx.doi.org/10.1109/vlsicircuits18222.2020.9162856.

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Karmakar, Shoubhik, Burak Gonen, Fabio Sebastiano, Robert Van Veldhoven та Kofi A. A. Makinwa. "A 280μW dynamic-zoom ADC with 120dB DR and 118dB SNDR in 1kHz BW". У 2018 IEEE International Solid-State Circuits Conference (ISSCC). IEEE, 2018. http://dx.doi.org/10.1109/isscc.2018.8310272.

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Youngcheol Chae, K. Souri, and K. A. A. Makinwa. "A 6.3µW 20b incremental zoom-ADC with 6ppm INL and 1µV offset." In 2013 IEEE International Solid-State Circuits Conference (ISSCC 2013). IEEE, 2013. http://dx.doi.org/10.1109/isscc.2013.6487733.

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Erol, Osman Emir, Sule Ozev, Chandra Suresh, Rubin Parekhji, and Lakshmanan Balasubramanian. "On-Chip Measurement of Bandgap Reference Voltage using a Small Form Factor VCO Based Zoom-in ADC." In Design, Automation and Test in Europe. IEEE Conference Publications, 2015. http://dx.doi.org/10.7873/date.2015.1003.

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