Relevant bibliographies by topics / Α-Galacto-Oligosaccharides (α-GOS)

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  1. Journal articles
  2. Dissertations / Theses

Academic literature on the topic 'Α-Galacto-Oligosaccharides (α-GOS)'

Author: Grafiati
Published: 25 May 2024
Last updated: 31 July 2025

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Journal articles on the topic "Α-Galacto-Oligosaccharides (α-GOS)"

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Kruger, Claire, Yuting Zhou, Bjorn A. Thorsrud, Fanny Morel-Despeisse та Eric Chappuis. "Safety evaluation of α-galacto-oligosaccharides for use in infant formulas investigated in neonatal piglets". Toxicology Research and Application 1 (1 січня 2017): 239784731772282. http://dx.doi.org/10.1177/2397847317722828.

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Galacto-oligosaccharide (GOS), comprising galactoses with a glucose or sucrose, is a family of nondigestible oligosaccharides. The present study evaluates the safety of an α-GOS product (P-GOS® P) in a neonatal piglet model for 3 weeks. Three days after birth, neonatal piglets were divided into control and treated groups and provided with swine milk replacers in the absence and presence of 8 mg/mL—of the α-GOS product, respectively. An increase in the weight of the large intestines in treated males was noted, which is a common finding in studies of animals fed nondigestible oligosaccharides. T
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Djouzi, Zakia, and Claude Andlueux. "Compared effects of three oligosaccharides on metabolism of intestinal microflora in rats inoculated with a human faecal flora." British Journal of Nutrition 78, no. 2 (1997): 313–24. http://dx.doi.org/10.1079/bjn19970149.

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Using germ-free rats inoculated with a human faecal flora (gnotobiotic rats), the effects of three oligosaccharides (β-fructo-oligosaccharides (FOS), β-galacto-oligosaccharides (TOS) and α-gluco-oligosaccharides (GOS)) on intestinal bacterial metabolism were compared. The animals were fed on either a control diet or diets containing 4Og/kg of GOS, FOS or TOS. FOS and TOS were the preferred growth substrates for Bifidobacteria which increased in number by 2 log values in faeces of rats when compared with rats fed on GOS or control diets. Ingestion of TOS specifically induced hydrolysis of the s
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Chen, Tso-Hsiao, Chung-Te Liu, Chung-Yi Cheng, Yuh-Mou Sue, Nai-Jen Huang, and Cheng-Hsien Chen. "Oligosaccharides Ameliorate Acute Kidney Injury by Alleviating Cluster of Differentiation 44-Mediated Immune Responses in Renal Tubular Cells." Nutrients 14, no. 4 (2022): 760. http://dx.doi.org/10.3390/nu14040760.

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Acute kidney injury (AKI) is a sudden episode of kidney damage that commonly occurs in patients admitted to hospitals. To date, no ideal treatment has been developed to reduce AKI severity. Oligo-fucoidan (FC) interferes with renal tubular cell surface protein cluster of differentiation 44 (CD44) to prevent renal interstitial fibrosis; however, the influence of oligosaccharides on AKI remains unknown. In this study, FC, galacto-oligosaccharide (GOS), and fructo-oligosaccharide (FOS) were selected to investigate the influence of oligosaccharides on AKI. All three oligosaccharides have been prov
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Matsuki, T., S. Tajima, T. Hara, K. Yahagi, E. Ogawa, and H. Kodama. "Infant formula with galacto-oligosaccharides (OM55N) stimulates the growth of indigenous bifidobacteria in healthy term infants." Beneficial Microbes 7, no. 4 (2016): 453–61. http://dx.doi.org/10.3920/bm2015.0168.

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The objective of the study was to investigate whether an infant formula supplemented with galacto-oligosaccharides (GOS; OM55N) was able to stimulate the growth of indigenous bifidobacteria and to establish microbiota similar to that of breastfed infants. A randomised, double-blind, placebo-controlled trial was performed using 35 healthy term infants (31-54 days of age; 42±6 days) to determine whether infant formula with 0.3 g/dl GOS (OM55N) stimulated the growth of bifidobacteria in the infants’ guts. At the trial onset and 2 weeks after, the infants’ faecal samples were examined for microbio
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Godínez-Méndez, Lucila A., Carmen M. Gurrola-Díaz, José Sergio Zepeda-Nuño, et al. "In Vivo Healthy Benefits of Galacto-Oligosaccharides from Lupinus albus (LA-GOS) in Butyrate Production through Intestinal Microbiota." Biomolecules 11, no. 11 (2021): 1658. http://dx.doi.org/10.3390/biom11111658.

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Animal digestive systems host microorganism ecosystems, including integrated bacteria, viruses, fungi, and others, that produce a variety of compounds from different substrates with healthy properties. Among these substrates, α-galacto-oligosaccharides (GOS) are considered prebiotics that promote the grow of gut microbiota with a metabolic output of Short Chain Fatty Acids (SCFAs). In this regard, we evaluated Lupinus albus GOS (LA-GOS) as a natural prebiotic using different animal models. Therefore, the aim of this work was to evaluate the effect of LA-GOS on the gut microbiota, SCFA producti
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Cervera-Tison, M., L. E. Tailford, C. Fuell та ін. "Functional Analysis of Family GH36 α-Galactosidases from Ruminococcus gnavus E1: Insights into the Metabolism of a Plant Oligosaccharide by a Human Gut Symbiont". Applied and Environmental Microbiology 78, № 21 (2012): 7720–32. http://dx.doi.org/10.1128/aem.01350-12.

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ABSTRACTRuminococcus gnavusbelongs to the 57 most common species present in 90% of individuals. Previously, we identified an α-galactosidase (Aga1) belonging to glycoside hydrolase (GH) family 36 fromR. gnavusE1 (M. Aguilera, H. Rakotoarivonina, A. Brutus, T. Giardina, G. Simon, and M. Fons, Res. Microbiol. 163:14–21, 2012). Here, we identified a novel GH36-encoding gene from the same strain and termed itaga2. Althoughaga1showed a very simple genetic organization,aga2is part of an operon of unique structure, including genes putatively encoding a regulator, a GH13, two phosphotransferase system
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Lian, Puqiao, Paul A. J. Henricks, Harry J. Wichers, Gert Folkerts, and Saskia Braber. "Differential Effects of Oligosaccharides, Antioxidants, Amino Acids and PUFAs on Heat/Hypoxia-Induced Epithelial Injury in a Caco-2/HT-29 Co-Culture Model." International Journal of Molecular Sciences 24, no. 2 (2023): 1111. http://dx.doi.org/10.3390/ijms24021111.

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(1) Exposure of intestinal epithelial cells to heat and hypoxia causes a (heat) stress response, resulting in the breakdown of epithelial integrity. There are indications that several categories of nutritional components have beneficial effects on maintaining the intestinal epithelial integrity under stress conditions. This study evaluated the effect of nine nutritional components, including non-digestible oligosaccharides (galacto-oligosaccharides (GOS), fructo-oligosaccharides (FOS), chitosan oligosaccharides (COS)), antioxidants (α-lipoic acid (ALA), resveratrol (RES)), amino acids (l-gluta
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Yao, Qi, Wenbo Zhang, Yuze Wang, et al. "Lactobacillus plantarum and Galacto-Oligosaccharides Synbiotic Relieve Irritable Bowel Syndrome by Reshaping Gut Microbiota and Attenuating Mast Cell Hyperactivation." Nutrients 17, no. 10 (2025): 1670. https://doi.org/10.3390/nu17101670.

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Background: Irritable bowel syndrome (IBS) significantly impairs the lifestyle and quality of life of the global population. However, the underlying pathophysiological mechanisms remain largely elusive. While conventional pharmacological approaches show limited therapeutic efficacy, emerging microbiota-targeted dietary interventions present promising alternatives. Objectives: The present study aimed to elucidate the molecular mechanisms by which a synbiotic mitigates IBS and associated colonic dysfunctions in C57BL/6 mice. Methods: The mouse model was induced by a Citrobacter rodentium (C. rod
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Pico, Joana, Natalia P. Vidal, Listiya Widjaja, Louis Falardeau, Lionel Albino та Mario M. Martinez. "Development and assessment of GC/MS and HPAEC/PAD methodologies for the quantification of α-galacto-oligosaccharides (GOS) in dry beans (Phaseolus vulgaris)". Food Chemistry 349 (липень 2021): 129151. http://dx.doi.org/10.1016/j.foodchem.2021.129151.

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Yao, Qianqian, Huiying Li, Yanan Gao, Nan Zheng, Véronique Delcenserie, and Jiaqi Wang. "The Milk Active Ingredient, 2′-Fucosyllactose, Inhibits Inflammation and Promotes MUC2 Secretion in LS174T Goblet Cells In Vitro." Foods 12, no. 1 (2023): 186. http://dx.doi.org/10.3390/foods12010186.

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In several mice inflammatory models, human milk oligosaccharides (HMOs) were shown to protect the intestinal barrier by promoting mucin secretion and suppressing inflammation. However, the functions of the individual HMOs in enhancing mucin expression in vivo have not been compared, and the related mechanisms are not yet to be clarified. In this study, we investigated the modulatory effects of 2′-fucosyllactose (2′-FL), 3′-sialyllactose (3′-SL), galacto-oligosaccharide (GOS) and lactose (Lac) on goblet cells’ functions in vitro. The appropriate dosage of the four chemicals was assessed in LS17
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Dissertations / Theses on the topic "Α-Galacto-Oligosaccharides (α-GOS)"

1

Chartrel, Valentine. "Fonctionnalisation d’une matrice végétale à base de pois protéagineux (Pisum sativum) par voie microbienne." Electronic Thesis or Diss., université Paris-Saclay, 2020. http://www.theses.fr/2020UPASB029.

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ROQUETTE transforme et valorise le pois (Pisum sativum) pour produire des protéines, des fibres et des amidons. Au cours du procédé, diffé-rentes fractions secondaires sont générées dont le soluble de pois, désigné LAB 4960 après atomisation. Ce coproduit riche en fibres est inapte pour la nutrition humaine car il peut causer des désordres diges-tifs, engendrés par la forte teneur en α-GOS, des α-galacto-oligosaccharides formés de 1 à 3 unités de galactose liées par des liaisons α-(1-6). Parmi les α-GOS, on retrouve le raffinose, le stachyose et le verbascose qui sont non digérés par l’homme m
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