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Artykuły w czasopismach na temat "Antitumoral properties"

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Fabiani, Roberto. "Antitumoral Properties of Natural Products." Molecules 25, no. 3 (2020): 650. http://dx.doi.org/10.3390/molecules25030650.

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McLachlan, J. A., C. D. Serkin, K. M. Morrey, and O. Bakouche. "Antitumoral properties of aged human monocytes." Journal of Immunology 154, no. 2 (1995): 832–43. http://dx.doi.org/10.4049/jimmunol.154.2.832.

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Abstract It is known that older people are more sensitive to cancer and infectious agents and need more time to recover from such disorders. Can this difference in sensitivity to cancer and infections between elderly and younger people be a result of a difference in their immune systems and, more specifically, in the way monocytes react to infectious agents and cancer cells? To determine what happens after cells have aged, human monocytes were purified from young donors (approximately 25 years of age) and from older donors (65 years of age or older) and tested for their ability to respond to t
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Braca, A. "Insight on antitumoral properties of plant diterpenes." Planta Medica 81, S 01 (2016): S1—S381. http://dx.doi.org/10.1055/s-0036-1596105.

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Pandiella-Alonso, Atanasio, Elena Díaz-Rodríguez, and Eduardo Sanz. "Antitumoral Properties of the Nutritional Supplement Ocoxin Oral Solution: A Comprehensive Review." Nutrients 12, no. 9 (2020): 2661. http://dx.doi.org/10.3390/nu12092661.

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Ocoxin Oral Solution (OOS) is a nutritional supplement whose formulation includes several plant extracts and natural products with demonstrated antitumoral properties. This review summarizes the antitumoral action of the different constituents of OOS. The action of this formulation on different preclinical models as well as clinical trials is reviewed, paying special attention to the mechanism of action and quality of life improvement properties of this nutritional supplement. Molecularly, its mode of action includes a double edge role on tumor biology, that involves a slowdown in cell prolife
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Lungu, Claudiu N., Bogdan Ionel Bratanovici, Maria Mirabela Grigore, Vasilichia Antoci, and Ionel I. Mangalagiu. "Hybrid Imidazole-Pyridine Derivatives: An Approach to Novel Anticancer DNA Intercalators." Current Medicinal Chemistry 27, no. 1 (2020): 154–69. http://dx.doi.org/10.2174/0929867326666181220094229.

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Lack of specificity and subsequent therapeutic effectiveness of antimicrobial and antitumoral drugs is a common difficulty in therapy. The aim of this study is to investigate, both by experimental and computational methods, the antitumoral and antimicrobial properties of a series of synthesized imidazole-pyridine derivatives. Interaction with three targets was discussed: Dickerson-Drew dodecamer (PDB id 2ADU), G-quadruplex DNA string (PDB id 2F8U) and DNA strain in complex with dioxygenase (PDB id 3S5A). Docking energies were computed and represented graphically. On them, a QSAR model was deve
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Iacopetta, Domenico, Jessica Ceramella, Alessia Catalano, et al. "Schiff Bases: Interesting Scaffolds with Promising Antitumoral Properties." Applied Sciences 11, no. 4 (2021): 1877. http://dx.doi.org/10.3390/app11041877.

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Schiff bases, named after Hugo Schiff, are highly reactive organic compounds broadly used as pigments and dyes, catalysts, intermediates in organic synthesis, and polymer stabilizers. Lots of Schiff bases are described in the literature for various biological activities, including antimalarial, antibacterial, antifungal, anti-inflammatory, and antiviral. Schiff bases are also known for their ability to form complexes with several metals. Very often, complexes of Schiff bases with metals and Schiff bases alone have demonstrated interesting antitumor activity. Given the innumerable vastness of d
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Perez-Tomas, R., and M. Vinas. "New Insights on the Antitumoral Properties of Prodiginines." Current Medicinal Chemistry 17, no. 21 (2010): 2222–31. http://dx.doi.org/10.2174/092986710791331103.

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Esteruelas, Gerard, Eliana B. Souto, Marta Espina, et al. "Diclofenac Loaded Biodegradable Nanoparticles as Antitumoral and Antiangiogenic Therapy." Pharmaceutics 15, no. 1 (2022): 102. http://dx.doi.org/10.3390/pharmaceutics15010102.

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Cancer is identified as one of the main causes of death worldwide, and an effective treatment that can reduce/eliminate serious adverse effects is still an unmet medical need. Diclofenac, a non-steroidal anti-inflammatory drug (NSAID), has demonstrated promising antitumoral properties. However, the prolonged use of this NSAID poses several adverse effects. These can be overcome by the use of suitable delivery systems that are able to provide a controlled delivery of the payload. In this study, Diclofenac was incorporated into biodegradable polymeric nanoparticles based on PLGA and the formulat
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Adam, Gigi, Florina Daniela Cojocaru, Liliana Verestiuc, et al. "Assessing the Antioxidant Properties, In Vitro Cytotoxicity and Antitumoral Effects of Polyphenol-Rich Perilla leaves Extracts." Antioxidants 13, no. 1 (2023): 58. http://dx.doi.org/10.3390/antiox13010058.

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(1) Background: This study aimed to outline the antioxidant, antitumoral, and cytotoxic proprieties of various types of Perilla frutescens extracts obtained from the leaves of the species. (2) Methods: We determined total polyphenols, flavonoids and anthocyanins contents, as well as the in vitro antioxidant, antitumoral, and cytotoxic actions in three types of ethanolic extracts (E1, E2, E3) and in three types of acetone: ethanol extracts (A1, A2, A3) of Perilla frutescens according to standardized procedures. (3) Results: We found that Perilla frutescens ethanolic extracts had the highest tot
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Nava-Villalba, Mario, and Carmen Aceves. "6-Iodolactone, key mediator of antitumoral properties of iodine." Prostaglandins & Other Lipid Mediators 112 (August 2014): 27–33. http://dx.doi.org/10.1016/j.prostaglandins.2014.07.001.

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Rozprawy doktorskie na temat "Antitumoral properties"

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Panosa, Roqueta Clara. "Antitumoral properties of epidermal growth factor derivatives." Doctoral thesis, Universitat de Girona, 2015. http://hdl.handle.net/10803/369050.

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The members of the epidermal growth factor (EGF) / ErbB family are prime targets for cancer therapy. However, the therapeutic efficiency of the existing anti-ErbB agents is limited. Thus, identifying new molecules that inactivate the ErbB receptors through novel strategies is an important goal on cancer research. In this thesis work we have developed a shorter form of human EGF (EGFt) with a truncated C-terminal as a novel EGFR inhibitor. EGFt was designed based on the superimposition of the three-dimensional structures of EGF and the Potato Carboxypeptidase Inhibitor (PCI), an EGFR blocker pr
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Tonello, Andrea <1988&gt. "Synthesis and Engineering of PLGA-based Nanoparticles with antitumoral Properties." Master's Degree Thesis, Università Ca' Foscari Venezia, 2014. http://hdl.handle.net/10579/5394.

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Nano-based delivery systems have attracted a great deal of attention in the past two decades as a strategy to overcome the low therapeutic index of conventional anticancer drugs. Nanoparticles enable the delivery of a great variety of drugs including analgesics, anti-Alzheimer's drugs, cardiovascular drugs, and several macromolecules into the brain after intravenous injection of animals. The mechanism of nanoparticle-mediated drug transport across the blood-brain barrier appears to be receptor-mediated endocytosis followed by drug release within the endothelial cells. Modification of the nanop
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Zou, Yu. "Dendrimères et dendrons phosphorés : synthèse, propriétés et applications en nanomédecine." Electronic Thesis or Diss., Université de Toulouse (2023-....), 2024. http://www.theses.fr/2024TLSES093.

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L'objectif de ce travail de thèse a été de préparer de nouveaux dendrimères ou dendrons phosphorés, qu'ils soient neutres, cationiques ou anioniques, dans le but d'élargir le panel des applications dans le domaine de la nanomédecine en tant que molécules actives par elles-mêmes ou en association avec certains médicaments. Au chapitre 1, la synthèse d'un nouveau dendrimère phosphoré polycationique comportant en surface 5 groupements pyrrolidinium et une amine protonnée a été menée à bien. Ce dendrimère associé au microRNA-30d permet d'obtenir des polyplexes qui sont transférés dans les cellules
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Salvador, Cátia Sofia Clemente. "Caracterização de cogumelos silvestres da espécie Amanita ponderosa: produção de metabolitos com atividade biológica." Doctoral thesis, Universidade de Évora, 2014. http://hdl.handle.net/10174/13391.

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Amanita ponderosa é uma espécie de cogumelos silvestres, comestível, característica de alguns microclimas mediterrânicos, existente na Península Ibérica. Neste estudo, avaliaram-se as propriedades biológicas e toxicológicas destes cogumelos e culturas, com vista a valorizar o seu potencial biotecnológico. Desenvolveu-se também uma metodologia de monitorização, utilizando técnicas de microanálise e imunológicas para screening e análise da especificidade de produção dos compostos bioativos. Os corpos de frutificação apresentaram um relevante conteúdo mineral e um perfil molecular correlacionável
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Brink, Susanna. "Structure-activity relationships of titanocene complexes with antitumor properties." Pretoria : [s.n.], 2003. http://upetd.up.ac.za/thesis/available/etd-09052005-101713/.

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Chen, Chujian 1966. "Antitumor properties of kefir : possible bioactive component(s) and mechanism(s)." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=85139.

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Research on the putative health benefits has indicated that kefir, a traditional fermented milk, might have antimutagenic and antitumor properties. The major objective of the present thesis was to isolate and identify antitumor compounds in cow's milk kefir and investigate the possible mechanisms involved. High speed centrifugation (HSC), molecular weight cut-off filtration (MWCO), size exclusion high performance liquid chromatography (SEC-HPLC) and reverse phase-HPLC (RP-HPLC) were utilized for fractionation of kefir and a cell culture model was developed to screen for the antiprolifer
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Sun, Wai-yin Raymond, and 辛偉賢. "The antitumor and antiviral properties of gold (III) porphyrins and their related complexes." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31245973.

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Zhang, Zhouen. "Tumor-targeting antitumor prodrugs and noninvasive molecular imaging probes : designs, syntheses and properties." 京都大学 (Kyoto University), 2005. http://hdl.handle.net/2433/144557.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(工学)<br>甲第11886号<br>工博第2579号<br>新制||工||1361(附属図書館)<br>23666<br>UT51-2005-N720<br>京都大学大学院工学研究科物質エネルギー化学専攻<br>(主査)教授 西本 清一, 教授 中條 善樹, 教授 木村 俊作<br>学位規則第4条第1項該当
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BUSA', Rosalia. "Evaluation of antitumor and immunomodulatory properties of Indicaxanthin from Opuntia Ficus Indica (L. Mill) fruit." Doctoral thesis, Università degli Studi di Palermo, 2020. http://hdl.handle.net/10447/395264.

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Cancer is a growing health problem around the world and according to estimates from the International Agency for Research on Cancer (IARC), 14.1 million new cancer cases and 8.2 million cancer deaths worldwide have been reported in 2012 (Ferlay et al., 2015). By 2030, the global burden is expected to grow to 21.7 million new cancer cases and 13 million cancer deaths simply due to the growth and aging of the population. Indicaxanthin ((2S)-2,3-dihydro-4-[2-[(2S)-2a-carboxypyrrolidin-1- yl]ethenyl]pyridine-2a,6-dicarboxylic acid), a betalain pigment from cactus pear fruit, has been the object o
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Medvetz, Douglas Allen. "The Synthesis, Characterization, and Antitumor Properties of Ag(I), Cu(II), and Rh(III) Metal Complexes." University of Akron / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=akron1216840371.

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Książki na temat "Antitumoral properties"

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Fang, Evandro Fei, and Tzi Bun Ng, eds. Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds. Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6214-5.

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Antitumoral Properties of Natural Products. MDPI, 2020. http://dx.doi.org/10.3390/books978-3-03943-099-4.

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Antitumoral Properties of Natural Products. MDPI, 2020. http://dx.doi.org/10.3390/books978-3-03943-115-1.

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Antitumoral Properties of Natural Products. Mdpi AG, 2020.

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Fang, Evandro Fei, and Tzi Bun Ng. Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds. Springer, 2015.

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Fang, Evandro Fei, and Tzi Bun Ng. Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds. Springer, 2013.

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Fang, Evandro Fei, and Tzi Bun Ng. Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds. Springer, 2013.

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Fang, Evandro Fei, and Tzi Bun Ng. Antitumor Potential and Other Emerging Medicinal Properties of Natural Compounds. Springer London, Limited, 2013.

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Części książek na temat "Antitumoral properties"

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Varela, João, Catarina Vizetto-Duarte, Luísa Custódio, Luísa Barreira, and Fernando Albericio. "Marine Peptides and Proteins with Cytotoxic and Antitumoral Properties." In Marine Proteins and Peptides. John Wiley & Sons, Ltd, 2013. http://dx.doi.org/10.1002/9781118375082.ch19.

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Schumann, G. "Antiviral and Antitumor Effects of Liposome-Entrapped MTP-PE, a Lipophilic Muramylpeptide." In Biological Properties of Peptidoglycan, edited by Peter H. Seidl and Karl H. Schleifer. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110874297-032.

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Malik, Fayaz, and Suresh Kumar. "Sesquiterpenes from Essential Oils with Promising Antitumor Properties." In Bioactive Essential Oils and Cancer. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-19144-7_9.

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Attaway, John A. "Citrus Juice Flavonoids with Anticarcinogenic and Antitumor Properties." In ACS Symposium Series. American Chemical Society, 1993. http://dx.doi.org/10.1021/bk-1994-0546.ch019.

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Köpf-Maier, P. "Organometallic Titanocene and Ferricenium Complexes: Antitumor and Toxicologic Properties." In Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-1717-3_66.

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Silbert, Jeremiah. "Lectins: Personal Comments of Nathan Sharon Taken from his Memoirs (Translation from Hebrew)." In Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds. Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6214-5_1.

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Vago, Riccardo, Rodolfo Ippoliti, and Maria Serena Fabbrini. "Current Status and Biomedical Applications of Ribosome-Inactivating Proteins." In Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds. Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6214-5_10.

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Kennedy, Ann R. "The Health Benefits of the Bowman-Birk Inhibitor." In Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds. Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6214-5_11.

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Rolka, Krzysztof, Adam Lesner, Anna Łęgowska, and Magdalena Wysocka. "Peptidic Inhibitors of Serine Proteinases of Plant Origin." In Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds. Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6214-5_12.

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Furukawa, Kenei, Tadashi Uwagawa, and Katsuhiko Yanaga. "Anti-Tumor Effect of Synthetic Serine Protease Inhibitor." In Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds. Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6214-5_13.

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Streszczenia konferencji na temat "Antitumoral properties"

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Kavok, Nataliya, Vladimir Klochkov, Galyna Dudetskaya, Olga Sidorenko, and Olga Sedyh. "The Antitumor Efficacy of Redox-Active Inorganic Nanoparticles/Menadione Complexes in 2D and 3D Models of L929 Fibrosarcoma Cells." In 2024 IEEE 14th International Conference Nanomaterials: Applications & Properties (NAP). IEEE, 2024. http://dx.doi.org/10.1109/nap62956.2024.10739771.

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Marliyana, Soerya Dewi, Maulidan Firdaus, Muhamad Widyo Wartono, Diana Inas Utami, and Uly Wulan Apriani. "Evaluation of the Antibacterial Activity of Pinostrobin Derivative Compounds from Ethylation and Allylation Reactions." In 8th International Conference on Advanced Material for Better Future. Trans Tech Publications Ltd, 2025. https://doi.org/10.4028/p-s3ucax.

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Temu Kunci (Kaempferia pandurata Roxb.) is one of the plants from the Zingiberaceae family that contains secondary metabolites derived from flavonoids. Studies on the bioactivity of flavonoid compounds from this species have shown various biological activities such as antibacterial, antioxidant, antiviral, antitumor, antipyretic, anti-inflammatory, analgesic, and insecticidal properties. Pinostrobin (5-hydroxy-7-methoxy flavanone) (1) is the major flavonoid found in the rhizomes of this plant and has been successfully derivatized through ethylation and allylation reactions. Two compounds were
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Bezerra, Natércia M. M., Gardênia C. G. Militão, Terezinha G. da Silva, Paulo H. Menezes, and Roberta A. Oliveira. "Synthesis of Combretastatin A-4 Analogs with Antitumoral Properties." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0272-1.

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Lázaro, Rocío S. García, Humberto Lamdan, Norailys Lorenzo Perez, et al. "Abstract 3455: Preclinical evidences of antitumoral properties of a Yerba mate extract on breast and colon cancer models." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-3455.

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Yu, Henry, Hong-Ming Hu, Rongliang Lou, et al. "1171 CAN1012: a selective and potent TLR7 agonist with strong antitumoral properties mediated by localized innate immune activation." In SITC 37th Annual Meeting (SITC 2022) Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/jitc-2022-sitc2022.1171.

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Tikhonov, Sergey, Nataliya Tikhonova, N. V. Merzlyakova, and A. S. Ozhgihina. "PEPTIDES AS A FUNCTIONAL INGREDIENT FOR PREVENTIVE PRODUCTS." In I International Congress “The Latest Achievements of Medicine, Healthcare, and Health-Saving Technologies”. Kemerovo State University, 2023. http://dx.doi.org/10.21603/-i-ic-133.

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Clinical studies indicate that products from cow colostrum are well tolerated by the&#x0D; human body, non-toxic and safe for consumption. The aim of this study is to study the&#x0D; antitumor properties of isolated individual peptides from corvine colostrum on the cell line of&#x0D; rat glioblastoma C6. The study revealed that peptide R1 has antitumor activity, therefore it can&#x0D; be used as a functional ingredient in food products.
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Philippova, J. G. ,., J. A. Shevchenko, M. S. Fisher, et al. "ANTITUMOR ACTIVITY AND PHENOTYPIC PROPERTIES OF GD2-SPECIFIC CAR T CELLS IN VITRO AND IN VIVO." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-357.

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In this study antigen-specific T cells expressing chimeric antigen receptor (CAR) targeting disialoganglioside (GD2) and GITR ligand were generated using retroviral transduction. The generated GD2-specific CAR T cells exhibited antitumor activity and antigen-specific properties in vitro and in vivo against GD2+ tumor cell lines.
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Patlay, A. A., M. E. Shmelev, V. E. Silant’ev, and A. S. Belousov. "CREATION AND CHARACTERIZATION OF HYDROGELS BASED ON MODIFIED PECTINS WITH CUSTOMIZABLE PROPERTIES FOR THE THERAPY OF BRAIN TUMORS." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-112.

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We have developed pectin hydrogels and coatings suitable for remodeling the extracellular matrix of the central nervous system with adjustable viscoelastic and structural properties. Hydrogels have shown antitumor effect on glioblastoma C6 and U87MG cultures by reducing cell proliferation and migration, which makes them promising materials for combination therapy of glioma.
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Dezvareh, Homa. "Abstract 5319: Apoptotic properties of platinum antitumor agents phosphaplatins." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-5319.

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Cibotaru, Sandu, Andreea-Isabela Sandu, Dalila Belei, and Luminita Marin. "Water Soluble PEGylated phenothiazines. Synthesis, Characterization and Antitumor Properties." In The First International Conference on “Green” Polymer Materials 2020. MDPI, 2020. http://dx.doi.org/10.3390/cgpm2020-07215.

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