Готові списки джерел за темами / 2KO

Добірка наукової літератури з теми "2KO"

Автор: Grafiati
Опубліковано: 23 вересня 2022
Оновлено: 27 січня 2023

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Статті в журналах з теми "2KO":

1

Shashidharamurthy, Rangaiah, Charles Parkos, Periasamy Selvaraj, and Matam Vijay-Kumar. "Lipocalin-2 is involved in immune-complex mediated inflammation (102.23)." Journal of Immunology 186, no. 1_Supplement (April 1, 2011): 102.23. http://dx.doi.org/10.4049/jimmunol.186.supp.102.23.

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Abstract Lipocalin-2 (Lcn-2) is an innate immune protein whose expression is upregulated by several orders of magnitude in response to inflammation/injury/infection by variety of cells including neutrophils. However, the role of Lcn-2 induction in IC-induced inflammation is largely unknown. Here in, we have investigated the role of Lcn-2 during IC-mediated inflammation using Lcn-2 knock out (Lcn-2KO) and wild type (WT) mice. IC-mediated inflammation upregulated systemic Lcn-2 in WT mice when compared to naïve mice. The neutrophil chemoattractant KC was significantly elevated in WT, but not in Lcn-2KO mice, in response to IC-induced inflammation. Consistently Lcn-2KO mice showed about 50% reduced IC-mediated inflammation when compared to WT mice. Histopathological analysis of skin biopsy showed reduced inflammatory cell infiltration at inflamed site in Lcn-2KO mice relative to WT mice. Administration of recLcn-2 into Lcn-2KO mice resulted in inflammation similar to that of WT mice in response to IC. Lastly, we observed that neutralization of Lcn-2 via neutralizing mAb significantly reduced inflammation in WT mice. These results suggest that engagement of FcγRs expressed on local inflammatory cells with ICs leads to the induction of Lcn-2. Such IC-induced Lcn-2 expression may be essential for infiltration inflammatory cells at the site of inflammation. Our studies show that therapeutic targeting of Lcn-2 may be useful approach for treating IC-mediated inflammatory/autoimmune diseases
2

Nakamura, Yuri, Ko Sato, Hideki Yamamoto, Kana Matsumura, Ikumi Matsumoto, Toshiki Nomura, Tomomitsu Miyasaka, et al. "Dectin-2 Deficiency Promotes Th2 Response and Mucin Production in the Lungs after Pulmonary Infection with Cryptococcus neoformans." Infection and Immunity 83, no. 2 (November 24, 2014): 671–81. http://dx.doi.org/10.1128/iai.02835-14.

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Dectin-2 is a C-type lectin receptor that recognizes high mannose polysaccharides.Cryptococcus neoformans, a yeast-form fungal pathogen, is rich in polysaccharides in its cell wall and capsule. In the present study, we analyzed the role of Dectin-2 in the host defense againstC. neoformansinfection. In Dectin-2 gene-disrupted (knockout) (Dectin-2KO) mice, the clearance of this fungus and the inflammatory response, as shown by histological analysis and accumulation of leukocytes in infected lungs, were comparable to those in wild-type (WT) mice. The production of type 2 helper T (Th2) cytokines in lungs was higher in Dectin-2KO mice than in WT mice after infection, whereas there was no difference in the levels of production of Th1, Th17, and proinflammatory cytokines between these mice. Mucin production was significantly increased in Dectin-2KO mice, and this increase was reversed by administration of anti-interleukin 4 (IL-4) monoclonal antibody (MAb). The levels of expression of β1-defensin, cathelicidin, surfactant protein A (Sp-A), and Sp-D in infected lungs were comparable between these mice. Inin vitroexperiments, IL-12p40 and tumor necrosis factor alpha (TNF-α) production and expression of CD86 and major histocompatibility complex (MHC) class II by bone marrow-derived dendritic cells and alveolar macrophages were completely abrogated in Dectin-2KO mice. Finally, the disrupted lysates ofC. neoformans, but not of whole yeast cells, activated Dectin-2-triggered signaling in an assay with nuclear factor of activated T cells (NFAT)-green fluorescent protein (GFP) reporter cells expressing this receptor. These results suggest that Dectin-2 may oppose the Th2 response and IL-4-dependent mucin production in the lungs after infection withC. neoformans, and it may not be required for the production of Th1, Th17, and proinflammatory cytokines or for clearance of this fungal pathogen.
3

Ishii, Keiko, Yukiko Akahori, Masahiko Toyama, Tetsuji Aoyagi, Natsuo Yamamoto, Shinobu Saijo, Yoichiro Iwakura, Sho Yamasaki, and Kazuyoshi Kawakami. "Role of Dectin-2 in the host defense against Streptococcus pneumoniae infection (45.8)." Journal of Immunology 188, no. 1_Supplement (May 1, 2012): 45.8. http://dx.doi.org/10.4049/jimmunol.188.supp.45.8.

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Abstract Streptococcus pneumoniae possesses a thick polysaccharide capsule. Host defense to this bacterium is mediated by neutrophilic inflammatory responses, which is critically regulated by innate immune mechanism. S. pneumoniae has been reported to be sensed by pattern-recognition receptors such as TLR2, TLR4 and SIGN-R1. In this study, we examined the role of Dectin-2 in the host defense to S. pneumoniae infection. When bone marrow-derived dendritic cells from wild-type (WT) and Dectin-2KO mice were stimulated with culture supernatants (Sup) of a strain of S. pneumoniae (URF918) or its ConA-bound fraction, IL-12p40 production was abrogated in Dectin-2KO mice. In a NFAT-GFP reporter assay, Sup provided a positive signal in Dectin-2 gene-transfected reporter cells. These results suggest that Dectin-2 senses mannose-containing polysaccharides in S. pneumoniae capsule. Dectin-2KO mice infected intratracheally with S. pneumoniae showed shorter survival and larger bacterial burden and lower IFN-γ production in lungs than WT mice. Although the neutrophilic infiltration in lungs was equivalent in both mice, the ratio of engulfed/un-engulfed neutrophils was lower in KO mice than in WT mice. The levels of anti-pneumococcal polysaccharide Ab in bronchoalveolar lavage fluid and serum were lower in KO mice than WT mice. These results suggest that Dectin-2 plays critical roles in the host defense to S. pneumoniae infection through promoting the Ab-mediated phagocytosis by neutrophils.
4

Fritz, Niklas M., Ingo Ludolph, Andreas Arkudas, Raymund E. Horch, and Aijia Cai. "The influence of K-wire transfixation on proximalization of the first metacarpal after resection suspension interposition arthroplasty." Archives of Orthopaedic and Trauma Surgery 141, no. 3 (January 25, 2021): 535–41. http://dx.doi.org/10.1007/s00402-021-03780-9.

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Abstract Introduction Osteoarthritis of the first carpometacarpal joint is a common degenerative disease and surgical treatment includes resection suspension interposition arthroplasty (RSIA) with or without temporary transfixation of the first metacarpal. One major drawback includes proximalization of the first metacarpal during the postoperative course. Specific data comparing different transfixation techniques in this context is sparse. Materials and methods In this retrospective study, we measured the trapezial space ratio (TSR) in 53 hands before and after RSIA to determine the proximalization of the first metacarpal depending on the type of Kirschner (K)-wire transfixation. We, therefore, compared transfixation of the first metacarpal to the scaphoid with one K-wire (1K) to transfixation of the first metacarpal with two K-wires (2K), either to the carpus (2Ka), or to the second metacarpal (2Kb), or to both second metacarpal and carpus (2Kc). Results While preoperative TSR did not differ between group 1K and 2K (p = 0.507), postoperative TSR was significantly higher in group 2K compared to 1K (p = 0.003). Comparing subgroups, postoperative TSR was significantly higher in group 2Kc than 1K (p = 0.046), while we found no significant difference comparing either group 2Ka or 2Kb to 1K (p = 0.098; p = 0.159). Neither did we find a significant difference within 2K subgroups, comparing group 2Ka and 2Kb (p = 0.834), 2Ka and 2Kc (p = 0.615), or 2Kb and 2Kc (p = 0.555). Conclusions The results of our study suggest that transfixation with two K-wires should be preferred to transfixation with one K-wire after RSIA. Specifically, transfixation from first to second metacarpal and from first metacarpal to carpus resulted in least proximalization of the first metacarpal postoperatively.
5

Rangasamy, K., and N. Panchacharam. "An impact of different injection timing operating on chlorellea emersonii methyl ester (CEME) with best fuel (BF)." Journal of Optoelectronic and Biomedical Materials 14, no. 4 (December 20, 2022): 191–201. http://dx.doi.org/10.15251/jobm.2022.144.191.

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Biodiesel is a clean-burning, oxygenated monoalkyl-ester fuel manufactured from natural, renewable sources like new/used vegetable oils and animal fats. The injection time has a significant impact on engine performance, particularly pollutant emissions. The purpose of this research is to see if Chlorellea Emersonii methyl ester (CEME) can be used as a fuel alternative in a compression ignition (CI) engine. The CEME was synthesised using a transesterification technique, and the engine parameters (performance, emission, and combustion) were investigated using 20 (v/v%) biodiesel blends at retard, standard, and advanced injection timings (IT). In this study an alteration in injection timing were done with TRC and BF combination. Other than conventional injection timing of 23o bTDC three more injection timing included ie 24o bTDC (advance IT), 21o bTDC (retarded IT) and 22o bTDC (retarded IT). Outcome results showed 22o bTDC(retarded IT) with 2.12% improvement in BTE followed by 24.5%,35.15% and 90.2% reduction in HC,CO and smoke.
6

Schwalm, Stephanie, Tankica Maneva Timcheva, Iuliia Filipenko, Mahsa Ebadi, Lotte P. Hofmann, Uwe Zangemeister-Wittke, Josef Pfeilschifter, and Andrea Huwiler. "Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts." Biological Chemistry 396, no. 6-7 (June 1, 2015): 813–25. http://dx.doi.org/10.1515/hsz-2014-0289.

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Abstract Both of the sphingosine kinase (SK) subtypes SK-1 and SK-2 catalyze the production of the bioactive lipid molecule sphingosine 1-phosphate (S1P). However, the subtype-specific cellular functions are largely unknown. In this study, we investigated the cellular function of SK-2 in primary mouse renal mesangial cells (mMC) and embryonic fibroblasts (MEF) from wild-type C57BL/6 or SK-2 knockout (SK2ko) mice. We found that SK2ko cells displayed a significantly higher proliferative and migratory activity when compared to wild-type cells, with concomitant increased cellular activities of the classical extracellular signal regulated kinase (ERK) and PI3K/Akt cascades, and of the small G protein RhoA. Furthermore, we detected an upregulation of SK-1 protein and S1P3 receptor mRNA expression in SK-2ko cells. The MEK inhibitor U0126 and the S1P1/3 receptor antagonist VPC23019 blocked the increased migration of SK-2ko cells. Additionally, S1P3ko mesangial cells showed a reduced proliferative behavior and reduced migration rate upon S1P stimulation, suggesting a crucial involvement of the S1P3 receptor. In summary, our data demonstrate that SK-2 exerts suppressive effects on cell growth and migration in renal mesangial cells and fibroblasts, and that therapeutic targeting of SKs for treating proliferative diseases requires subtype-selective inhibitors.
7

Chen, Haimiao. "Character varieties of even classical pretzel knots." Studia Scientiarum Mathematicarum Hungarica 56, no. 4 (December 2019): 510–22. http://dx.doi.org/10.1556/012.2019.56.4.1439.

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Abstract For each even classical pretzel knot P(2k1 + 1, 2k2 + 1, 2k3), we determine the character variety of irreducible SL (2, ℂ)-representations, and clarify the steps of computing its A-polynomial.
8

Miyasaka, Tomomitsu, Yukiko Akahori, Namiko Miyamura, Masahiko Toyama, Shinobu Saijo, Yoichiro Iwakura, Yuki Kinjo, Kazunori Oishi, and Kazuyoshi Kawakami. "Role of Dectin-2 in the serotype-specific antibody production and host protection against Streptococcus pneumoniae infection caused by pneumococcal polysaccharide vaccine (166.8)." Journal of Immunology 188, no. 1_Supplement (May 1, 2012): 166.8. http://dx.doi.org/10.4049/jimmunol.188.supp.166.8.

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Abstract Anti-pneumococcal polysaccharide vaccine (PPV) induces the production of serotype-specific Ab including IgG2 in spite of its feature of thymus-independent antigen. It remains to be clarified how PPV causes a class-switching from IgM to IgG. Recently, C-type lectin receptors (CLR) sensing polysaccharides have garnered much attention in the host defense to fungal infection. In our recent study, Dectin-2, a CLR involved in the recognition of mannose-rich polysaccharides, has been found to play an important role in the host defense to pneumococcal infection. Therefore, in this study, we addressed how Dectin-2 was involved in the vaccine effect of PPV using a mouse model. The serum levels of anti-serotype 3 pneumococcal capsular polysaccharide (PPS-3) two weeks after vaccination were significantly reduced in Dectin-2 knockout (KO) mice compared to wild-type (WT) mice. Weight loss and hypothermia of mice caused by infection with Streptococcus pneumoniae (URF918) were improved in WT mice transferred with spleen cells from vaccinated WT mice compared to those from vaccinated Dectin-2KO mice. Similar tendency was observed in the survival of infected mice. In in vitro experiments, IL-12p40, TNF-α and IL-6 production by bone marrow-derived dendritic cells (BM-DCs) stimulated with PPV was abrogated in Dectin-2KO. These results suggest that Dectin-2 is involved in the PPV-induced serotype-specific Ab production and host protection through sensing the pneumococcal polysaccharide antigens.
9

Carico, Zachary Mark, Baojun Zhang, Kingshuk Choudhury, Yuan Zhuang, and Michael S. Krangel. "Mechanisms that diversify an otherwise intrinsically processive Trav-Traj recombination program." Journal of Immunology 198, no. 1_Supplement (May 1, 2017): 202.12. http://dx.doi.org/10.4049/jimmunol.198.supp.202.12.

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Abstract In DP thymocytes, the Tcra locus undergoes multiple rounds of V-J rearrangement in order to generate a functional TCRα chain. While Traj segment usage is strictly ordered from 5′ to 3′ as rearrangement proceeds, it is unclear to what degree Trav usage is also ordered. To test this, we assessed the Trav-Traj combinatorial repertoire in murine DP thymocytes using 5′ RACE followed by paired end sequencing. In 129Sv/J WT thymocytes, we found a clear bias toward proximal-proximal and distal-distal joins, but Trav-Traj pairings were highly diverse, even in primary V-J rearrangement. However, combinatorial diversity was highly constrained in HYα KI thymocytes, in which a fixed primary V-J rearrangement in the endogenous Tcra locus is the starting point for secondary rearrangements. Thus, secondary rearrangement is highly processive through the V and J arrays, but surprising diversity is introduced by primary rearrangement. Tcrd rearrangement precedes Tcra rearrangement in developing thymocytes. In INT1-2KO mice, CTCF site deletion biases Trdv usage toward the most proximal gene segments. These mice, like HYα KI, displayed a substantially constrained Tcra repertoire, with limited diversity of primary rearrangements. Thus, variable truncation of the Trav array by prior Tcrd rearrangement creates diversity in an otherwise highly processive Tcra rearrangement program by imparting combinatorial diversity to primary Tcra rearrangement. This diversification is functionally important, as Trav1-Traj33 pairing and MAIT cell abundance are substantially reduced in HYα and INT1-2KO mice.
10

McCann, BT, and RE Robson. "Scattering of HF Radio Waves from the Sea: A Review of the Theory Based upon a Simplified Model." Australian Journal of Physics 44, no. 5 (1991): 459. http://dx.doi.org/10.1071/ph910459.

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A simplified, physically intuitive model of diffuse scattering of radio waves from a rough surface is used to present a self-contained derivation of first- and second-order cross sections, essentially in agreement with the standard expressions. Incoherent addition of the second-order contributions (electromagnetic and hydrodynamic) leads to a cross section which is slightly different from the more rigorously derived cross sections of Barrick (1972b) and Johnstone (1975). A surface current v has been incorporated in this model, with the main change to the cross section being a frequency shift of the entire spectrum by an amount Llw = -2ko . v.
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Статті в журналах Дисертації Книги

Дисертації з теми "2KO":

1

Wang, Yazhou. "Influence of Dectin-1 and Dectin-2 receptors on the susceptibility to gut inflammation." Thesis, Sorbonne université, 2021. http://www.theses.fr/2021SORUS523.

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Une dysbiose du microbiote intestinal a été identifiée comme impliquée dans la pathogenèse des maladies inflammatoires chroniques de l'intestin (MICI). Il a été démontré que les interactions hôte-bactéries affectent le développement des MICI, tandis que le rôle des interactions hôte-champignons dans les MICI sont peu décrites. Les lectines de type C sont des récepteurs impliqués dans la reconnaissance de motifs du mycobiote et font les réponses immunitaires face aux agents pathogènes fongiques. Nous avons évalué l'impact de la déficience des récepteurs Dectin-1 (D-1KO), Dectin-2 (D-2KO) et de la double déficience (D-1/2KO) dans l'inflammation intestinale. L’absence de D-1 ou D-2 n’a pas modifié la gravité de l'inflammation intestinale, tandis que les souris D-1/2KO étaient résistantes à la colite. Le rôle protecteur de D-1/2KO a été confirmé chez des souris WT ayant reçu le microbiote intestinal desD-1/2KO, suggérant que la protection était largement due au microbiote. L'analyse du microbiote des souris D-1/2KO montre que le microbiote bactérien, et en particulier la famille des Lachnospiraceae, mais pas le mycobiote, présentait une forte modification par rapport aux souris WT. Une supplémentation en Blautia hansenii a pu également assurer la protection, appuyant que cette protection était largement médiée par le microbiote bactérien. Ces résultats montrent que la déficience D-1/2 protége les souris de la colite via une modulation du microbiote intestinal bactérien
Gut microbiota dysbiosis has been identified as being involved in the pathogenesis of inflammatory bowel disease (IBD). Host-bacterial interactions have been shown to affect the development of IBD, while the role of host-fungal interactions in IBD is poorly described. C-type lectins are receptors involved in the recognition of patterns of the mycobiota and shape the immune responses to fungal pathogens. We evaluated the impact of the deficiency of the receptors Dectin-1 (D-1KO), Dectin-2 (D-2KO) and dual deficiency (D-1/2KO) in intestinal inflammation. The absence of D-1 or D-2 did not alter the severity of intestinal inflammation, whereas D-1/2KO mice were resistant to colitis. The protective role of D-1/2KO was confirmed in WT mice receiving the gut microbiota of D-1/2KO by fecal transfer, suggesting that protection was largely due to the gut microbiota. Analysis of the microbiota of D-1/2KO mice shows that the bacterial microbiota, and in particular the Lachnospiraceae family, but not the mycobiota, showed a strong change compared to the microbiota of the WT mice. Blautia hansenii supplementation was also able to provide protection, supporting that this protection was largely mediated by the bacterial microbiota and not the fungal microbiota. These results show that D-1/2KO deficiency protect mice from DSS-induced colitis via modulation of the bacterial gut microbiota
2

DARIANIAN, ISAMEL. "Proprietes de transport ionique dans les verres de borates b#2o#3-li#2o-li#2so#4." Paris 7, 1988. http://www.theses.fr/1988PA077046.

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3

Wodarcyk, John J. Jr. "Stress corrosion cracking susceptibility of AISI No. 1018 steel in low SO 2CO 2O 2aqueous environments." Ohio University / OhioLINK, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1183988473.

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4

Ji, Kyuil. "Etudes de la composition des aerosols stratospheriques polaires au moyen des diagrammes de phase stables, metastables et cinetiques des systemes hno#3/h#2o, hcl/h#2o et h#2so#4/h#2o." Paris 7, 1994. http://www.theses.fr/1994PA077354.

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Ce travail entre dans la cadre d'une etude de la composition des aerosols stratospheriques dont les representants les plus importants sont les pscs (nuages stratospheriques polaires), lesquels fournissent le support a des reactions heterogenes qui via l'activation des composes chlores conduisent a la destruction de l'ozone polaire. Le reexamen, par microcalorimetrie et dsc du diagramme d'equilibre hno#3/h#2o obtenu au rechauffement de solutions prealablement trempees a la temperature de l'azote liquide, a permis de mettre en evidence un nouvel hydrate stable a fusion non congruente, dont la composition a ete determinee a l'aide du diagramme de tammann, le dihydrate hno#3. 2h#2o ou nad qui peut jouer un role dans la formation des pscs. La formation du nad a ete confirmee par mesure de tg et tc (temperatures de transition vitreuse et de cristallisation) et par une etude de diffraction des rx en utilisant une chambre de guinier-simon qui a aussi permis d'obtenir, pour la premiere fois, les spectres de rx des 3 hydrates : nad, nam et nat. L'etude des diagrammes cinetiques a montre que : - dans les conditions de la stratosphere polaire le refroidissement des solutions hno#3/h#2o ne pouvaient conduire a la formation du nad, qui peut neanmoins etre forme par co-condensation des vapeurs hno#3/h#2o ; - le retard supplementaire a la cristallisation introduit par l'utilisation d'emulsions (simulant la taille des aerosols stratospheriques) est suffisant pour interdire la cristallisation des solutions d'acide sulfurique dans les conditions de la stratosphere polaire. Un resultat semblable a ete obtenu avec les solutions hcl/h#2o qui ne peuvent donner que de la glace. Ces resultats mettent en evidence le role joue par les solutions aux cotes des pscs dans la chimie stratospherique polaire.
5

Lawley, Sue. "The investigation of regional ecology using 2km x 2km scale botanical distribution data." Thesis, University of Wolverhampton, 2010. http://hdl.handle.net/2436/134350.

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Tetrad vascular plant data from Staffordshire (VC 39), accumulated 1995 - 2009, were analysed using Two Way Indicator Species Analysis and Principal Components Analysis, explored using GIS, to examine major floristic distribution patterns. Environmental data were also examined using Redundancy Analysis. The strongest floristic trend was a human influence axis, arranged south—north, with the south being most anthropocentric and the north having a high proportion of semi-natural habitats. Indicator species for different parts of the County showed a corresponding strong biogeographic element, with ‘Southern-temperate’ and ‘Boreo-temperate’ characteristics in south and north respectively. The next most important factor in the distribution of plant species in Staffordshire was habitat quality and richness, which separated intensively-managed farmland from areas with seminatural habitats and from human influenced urban areas. Environmental variables associated with the main division in the data were mainly climate and altitude and the extent of developed land. Historic field patterns, identified by Staffordshire County Council, were associated with semi-natural habitats, linking an historical landscape characterisation with vascular plant analysis for the first time in the UK. The investigation set out to characterise and classify spatial units in terms of biodiversity importance, and to produce an objective ecological classification of the Staffordshire region based on botanical and physical features. The resulting classification characterises different areas of the County in terms of plant species composition, and has many potential applications in terms of nature conservation strategy development, targeting of resources and monitoring. A further aim was to facilitate the selection of indicator species for high quality habitats – the study has enabled revision of Staffordshire’s axiophyte plant list. Both the ecological classification and indicator species will be of strategic value because the information provided is authenticated by being based on objective analysis of a wide range of data. In Staffordshire, further work is required to develop environmental data, especially an effective dataset for hedges, while comparison of the data with historical botanical data could provide further information about the County’s previous environment. The techniques developed in the study could be used more widely to: produce of lists of key species, provide information for environmental modeling, climate change monitoring, target nature conservation activity, and to develop landscape strategies.
6

Mahé, Fabrice. "Etude des diagrammes de phases du systeme hno 3/h 2so 4/h 2o : composition et mecanismes de formation des aerosols stratospheriques." Orléans, 1999. http://www.theses.fr/1999ORLE2050.

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Ce travail s'inscrit dans le cadre d'une etude de la composition et des mecanismes de formation des aerosols stratospheriques servant de support aux reactions heterogenes qui conduisent a la destruction de l'ozone polaire, via l'activation des composes chlores et bromes. Le reexamen du diagramme d'equilibre hno 3/h 2o a permis l'identification par drx et spectroscopie raman d'une nouvelle transition de phase a 63 4\c nad nad x. Cette transition irreversible semble etre gouvernee par la nucleation de la phase x a des temperatures inferieures a 73\c. Apres confirmation des structures du nat et du nam par drx sur monocristaux, les structures des deux formes nad et nad x ont ete determinees pour la premiere fois. L'etude de l'arrangement moleculaire de ces deux formes a montre l'existence d'associations de molecules dans le solide de type (no 3. H 5o 2 +), intermediaire entre le nam (no 3. H 3o +), et le nat (no 3. H 7o 3 +). La construction des diagrammes cinetiques macroscopique et microscopique h 2so 4/h 2o (et des diagrammes d'equilibre associes) par dsc a permis de montrer que : - l'hydrate qui cristallise n'est pas, comme il est generalement admis, le sat, mais un melange sao/glace dans la partie diluee et sao/sat dans la partie riche en acide du diagramme ; le sao jouant un role clef dans la cristallisation des melanges sao/sat car sa nucleation intervient a plus haute temperature que celle du sat ; - les solutions d'acide sulfurique ne peuvent cristalliser dans la stratosphere polaire que lors d'episodes exceptionnellement froids quand la temperature s'abaisse en dessous de 85\c. L'etude du diagramme ternaire h 2so 4/hno 3/h 2o a ete aborde dans un domaine reduit de concentration. La comparaison des resultats obtenus avec des solutions diluees macroscopiques et microscopiques a permis de montrer, comme dans le cas des binaires hno 3/h 2o et h 2so 4/h 2o, l'existence d'un retard a la cristallisation du a la taille micronique des particules. Ce retard d'environ 30\c pour la branche de cristallisation de la glace et d'environ 7\c pour les melanges eutectiques est suffisant pour interdire aux temperatures de la stratosphere toute cristallisation d'hydrates de l'acide sulfurique et nitrique a partir des solutions diluees.
7

LAMARE, RODRIGO CAIADO DE. "SPEECH CODING AT AVERAGE RATES BELOW 2KB/S." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2001. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=1873@1.

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CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO
Esta dissertação propõe algoritmos para codificações de voz a taxas médias em torno de 1,2 Kb/s. Um esquema de quantização vetorial preditiva chaveada com desempenho superior aos esquemas previamente descritos na literatura é proposto e avaliado em canal com ou sem ruído. Detectores eficientes de período fundamental e de sons oclusivos e fricativos são examinados e adaptados ao codificador proposto. Técnicas de exitação a baixas taxas de bits são investigadas a fim de reproduzir uma boa qualidade de voz decodificada. O modelo de exitação mista em multi-bandas com três sub-bandas é adotado para codificar os quadros sonoros. Para os quadros surdos são empregadas técnicas de modelagem e síntese de sinais fricativos e oclusivos, capazes de oferecer qualidade de voz satisfatória, reduzindo a taxa de bits destes quadros para apenas 0,4 Kb/s. Técnicas de pós-filtragem para reduzir o ruído de codificação e melhorar a qualidade de voz reconstruída são também examinadas e comparadas em uma mesma plataforma. Para reduzir o nível de ruído ambiente são ainda analisados métodos de supressão de ruído. Finalmente, o codificador proposto é comparado ao padrão norte-americano Mixed Excitation Linear Prediction (MELP), por meios de teste de comparação do tipo A/B. Os testes realizados indicam que o sistema proposto, operando a 1,2 Kb/s, apresenta qualidade de voz ligeiramente superior ao MELP, operando a 2,4 Kb/s. Para situações de transcodificação, o codificador proposto também apresenta desempenho superior ao MELP.
This dissertation presents algorithms to encode at an avarage bit rate of 1.2 Kb/s. A novel switched-predictive vector quantiser technique that outperforms previously reported schemes is proposed and assessed under noise-free and noisy channels. Efficient detectors for the pitch period and fricative and stop sounds are examined and adapted to the proposed coder. Low bit rate excitation methods are investigated in order to reproduce rather high quality speech. A mixed multiband excitation approach with three sub-bands is employed to encode voiced frames. For unvoiced frames, fricatives and stops modelling and synthesis techniques are used. This approach has shown to provide high quality synthesised speech, whilts it reduces the bit rate to only 0.4 Kb/s for unvoiced frames. To reduce coding noise and improve decoded speech, post- filtering techniques are analysed and compared on the same plataform. To reduce background noise, noise suppression methods are also examined. Finally, the propose coder is evaluated against the North American Mixed Prediction (MELP) coder, through A/B comparison tests. Assessment results have shown that the proposed system, operating at 1.2 Kb/s, slightly outperformed the MELP coder, operating at 2.4 Kb/s. For tandem connection situations, the proposed algorithm has presented a superior performance than the MELP coder.
Esta disertación propone algoritmos para codificaciones de voz a tasas medias en torno de 1,2 Kb/s. Se propone un esquema de cuantización vectorial predictiva, con desempeño superior a los esquemas previamente descritos en la literatura. Este esquema se evalúa en canal con o sin ruido. Se examinan detectores eficientes de período fundamental y de sueños oclusivos y fricativos se adaptan al codificador propuesto. Técnicas de exitación a bajas tasas de bits son investigadas a fin de reproducir una boa calidad de voz decodificada. Se adopta el modelo de exitación mixta en multi-bandas con tres sub-bandas para codificar los cuadros sonoros. Para los cuadros surdos se emplean técnicas de modelación y síntesis de señales fricativos y oclusivos, capaces de ofrecer calidad de voz satisfactoria, reduciendo la tasa de bits de estos cuadros para apenas 0,4 Kb/s. También se examinan y se comparan las técnicas de pós-filtragen para reducir el ruido de codificación y mejorar la calidad de voz reconstruída. Para reducir el nível de ruído ambiente se analizan métodos de supresión de ruido. Finalmente, el codificador propuesto se compara al padrón norteamericano Mixed Excitation Lineal Prediction (MELP), por medio de pruebas de comparación del tipo LA/B. Las pruebas realizadas indican que el sistema propuesto, operando a 1,2 Kb/s, presenta calidad de voz ligeramente superior al MELP, operando a 2,4 Kb/s. Para situaciones de transcodificación, el codificador propuesto también presenta desempeño superior al MELP.
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PASSARELLO, J. PHILIPPE. "Etude thermodynamique des systemes hno#3-n#2o#5 et hno#3-h#2so#4-so#3-nh#4no#3 ; optimisation d'un procede de synthese des oleums nitriques et mise au point d'une nouvelle methode de preparation de l'agent nitrant n#2o#5." Paris, ENMP, 1996. http://www.theses.fr/1996ENMP0611.

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Le but de cette etude est d'optimiser et de mettre au point des procedes de synthese de melanges contenant n#2o#5, lesquels sont utilises pour la synthese modulable d'explosifs parfois peu faciles a obtenir par d'autres methodes. Il a ete ainsi possible grace a une caracterisation structurale des milieux h#2o-n#2o#5-so#3 par spectroscopie raman et la modelisation thermodynamique des equilibres chimiques et liquide-vapeur y intervenant de: optimiser le procede frejacques de synthese des oleums nitriques hno#3-n#2o#5 par distillation de hno#3-h#2so#4-so#3-nh#4no#3 mettre au point un nouveau procede de preparation de n#2o#5 pur a partir des oleums nitriques
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Atalaya, Chávez Ruth Analy. "Estudio de las tormentas geomagnéticas durante el ciclo solar 23o." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2015. https://hdl.handle.net/20.500.12672/12588.

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Estudia la relación entre las tormentas geomagnéticas con la actividad solar. Analiza los datos de los observatorios geomagnéticos (Hermanus, Alice, Huancayo, Kakioka y Boulder), durante los meses de octubre y noviembre del 2003. Estos datos son obtenidos por el Centro Mundial de Datos Geomagnéticos (CMDG). Implementa un programa en MATLAB para procesar dichos datos, obtiene como resultado perturbaciones súbitas del componente geomagnético H para cada observatorio. Estas perturbaciones son ocasionadas por la actividad solar que afecta al campo geomagnético y genera tormentas geomagnéticas. Se clasifica dichas tormentas según su intensidad mediante el índice Dst. El resultado son las súper tormentas geomagnéticas que se encuentran en un rango Dst ≤ 200nT.
Trabajo de suficiencia profesional
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DZWONKOWSKI, PIOTR. "Micro-generateur electrochimique li/b#2o#3+xli#2o/inse." Paris 6, 1990. http://www.theses.fr/1990PA066124.

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Des micro-generateurs en couches minces ont ete realises et etudies. Les structures sont constituees par l'empilement de couches minces: de lithium, d'electrolyte solide vitreux et d'inse. Les micro-generateurs ont une tension de l'ordre de 1. 5-2 v, un courant d'echange sur l'interface de l'ordre de 5. 10##9 a/cm#2. La valeur de coefficient de diffusion chimique du lithium dans la cathode est estimee a se situer entre 10##1#4-10##1#5 cm#2/s. Differents electrolytes solides du systeme b-o-li, b-o-li-cl et b-o-li-s ont ete envisages et les caracteristiques des micro-generateurs ont ete etudiees en fonction de la composition de l'electrolyte. La structure de l'electrolyte a ete etudiee par la spectroscopie d'absorption infrarouge. Une etude complete de l'impedance complexe des couches minces des verres alcalins a ete menee
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Книги з теми "2KO":

1

Giorgi, Giorgio, and Caroline Franco. Prêmio Design Museu da Casa Brasileira, 21o., 22o., 23o., 24o., 25o. Edited by Museu da Casa Brasileira. São Paulo, SP: Museu da Casa Brasileira, Secretaria da Cultura, Governo do Estado São Paulo, 2011.

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Aguascalientes (Mexico : State). Governor (1998-2004 : González González). 2do. informe. Aguascalientes: Gobierno del Estado, 2000.

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Drate, Spencer. Cool type 2wo. Hamburg: Gingko Press, 1999.

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Drate, Spencer. Cool type 2wo. Cincinnati, OH: North Light Books, 1999.

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Hidalgo (Mexico : State). Governor (1999-2005 : Núñez Soto). 2do informe de gobierno. Pachuca?: Estado de Hidalgo, 2001.

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Jalisco (Mexico). Governor (1995-2001 : Cárdenas Jiménez). 2do. informe de gobierno. Guadalajara?: Gobierno del Estado de Jalisco, 1997.

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7

Vranckx, Bridget. 2OO Tips apartamentos urbanos. Barcelona: NUMEN Arte a Través del Tiempo, 2012.

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8

Philias, Vasileios Iōannou. Koinōnika systēmata ston 20o aiōna. Athēna: Gutenberg, 1988.

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Mexico) Foro Bioclimático Binacional (2nd 2012 Ciudad Juárez. Memorias del 2do Foro Bioclimático Binacional. Ciudad Juárez, Chihuahua, México: Universidad Autónoma de Ciudad Juárez, 2013.

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Venezuela) Salón Nacional de Arte Aragua (26th 2001 Maracay. 26o Salón Nacional de Arte Aragua. Maracay, Aragua, Venezuela: Fundación Museo de Arte Contemporáneo de Maracay Mario Abreu, 2002.

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Частини книг з теми "2KO":

1

Béguin, Alain, Jean-Marc Soulié, Georg Süss-Fink, Jerome B. Keister, and David J. Bierederman. "Bis(triphenylphosphoranylidene)Ammonium μ-Carbonyl-1kC 2kC-Decacarbonyl-lk3 C,2k3 ,3k4 C -μ-Hydrido-lK:2k-triangulo -Triruthenate(1-)." In Inorganic Syntheses, 268–70. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470132630.ch41.

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2

Jozef Perelberg, Rosine. "The Central Phantasy of Acted Violence." In Psychoanalysts in Session, 62–66. Abingdon, Oxon; New York, NY: Routledge, 2021. | Series: The new library of psychoanalysis | “Published in French, 2016”–Title page verso.: Routledge, 2020. http://dx.doi.org/10.4324/9780429196751-2k.

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Zeller, Dieter. "Versuch über 2Kor 5,1-5." In Der zweite Korintherbrief, 380–94. Göttingen: Vandenhoeck & Ruprecht, 2012. http://dx.doi.org/10.13109/9783666535338.380.

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Stover, R. J., M. Wei, K. Ji, W. E. Brown, D. K. Gilmore, S. E. Holland, D. E. Groom, M. E. Levi, N. Palaio, and S. Perlmutter. "A 2K×2K High Resistivity CCD." In Optical Detectors For Astronomy II, 239–44. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-011-4361-5_24.

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5

Adler, Bernhard. "2K-Formierungen." In Native Epoxide und Epoxidharze - ein Beitrag zur ökologischen Chemie, 45–59. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-55614-6_6.

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6

Fujikami, J., H. Mukai, K. Sato, T. Hara, H. Ishii, and T. Yamamoto. "5m/2kA High-Tc Cable Conductor." In Advances in Superconductivity V, 1251–54. Tokyo: Springer Japan, 1993. http://dx.doi.org/10.1007/978-4-431-68305-6_279.

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7

Ngo, Khanh Dang. "Entstehungsgeschichte der Vorschriften §§ 22a–22o KWG." In Rechtsfolgen des Refinanzierungsregisters, 9–37. Wiesbaden: Springer Fachmedien Wiesbaden, 2012. http://dx.doi.org/10.1007/978-3-658-00479-8_2.

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8

Sun, Fu-Sheng, Cameron Draney, and F. H. Sam Froes. "Synthesis of Ti5Si3and Ti5Si3-2Mo Alloys." In High Performance Metallic Materials for Cost Sensitive Applications, 211–18. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118788028.ch24.

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9

Chivers, T. "Polymerization of (Sn)2to (Sn)X." In Inorganic Reactions and Methods, 174–75. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470145326.ch85.

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10

Becker, Eve-Marie. "Paulus als weinender Briefeschreiber (2Kor 2,4)." In Der zweite Korintherbrief, 11–26. Göttingen: Vandenhoeck & Ruprecht, 2012. http://dx.doi.org/10.13109/9783666535338.11.

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Тези доповідей конференцій з теми "2KO":

1

Touma, Z., D. Gladman, J. Su, N. M. Anderson, and M. B. Urowitz. "FRI0395 Sle disease activity index glucocorticoid index (SLEDAI-2KG) identifies more responders than sledai-2k." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.5519.

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2

Urowitz, M., DD Gladman, J. Su, NM Anderson, and Z. Touma. "S1D:5 Sle disease activity index glucocorticosteroid index (sledai-2kg) identifies more responders than sledai-2k." In 11th European Lupus Meeting, Düsseldorf, Germany, 21–24 March 2018, Abstract presentations. Lupus Foundation of America, 2018. http://dx.doi.org/10.1136/lupus-2018-abstract.5.

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Sari, Selma, Bahar Artim Esen, Ahmet Gül, Lale Öcal, and Murat İnanç. "P181 Comparison of SLEDAI-2K and SLEDAI-2KG (glucocorticoid) indexes in patients with systemic lupus erythematosus (SLE)." In 12th European Lupus Meeting. Lupus Foundation of America, 2020. http://dx.doi.org/10.1136/lupus-2020-eurolupus.223.

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Hariyadi, Setyo S. P., Bambang Junipitoyo, Wawan Aries Widodo, Imam Sonhaji, and Fungky Dyan Pertiwi. "Numerical Simulation Using Slats, Slots, and Flaps in Steady Flight Conditions." In The 2nd International Conference on Technology for Sustainable Development. Switzerland: Trans Tech Publications Ltd, 2022. http://dx.doi.org/10.4028/p-d376fs.

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At this time, it has become commonplace for aircraft to use high lift devices. The high lift devices used include flaps, slats, slots, elevators, ailerons, and others. This study examines the effect of multiple elements on the wing, especially the combination of slat slots and flaps in several configurations.. This research was conducted with numerical simulations on wing airfoil NACA 43018. The observed conditions were rectangular wing (no slats, slots, and flaps) compared to the use of slats, slots, and flaps under steady flight conditions. The angles of attack used are (α) = 0o, 2o, 4o, 6o, 8o, 10o,12o,15o, 16o,17o,19o, and 20o. Numerical simulation using Ansys 19.1 application with turbulent model k-ε realizable. The use of slats, slots, and flaps does not result in a shift in the stall point but tends to increase aerodynamic performance (CL/CD)which is very significant. By paying attention to pressure drag, viscous drag and the resulting induced drag, the use of slats, slots, and flaps reduces a large amount of induced drag so that the lift to drag ratio increases.
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Phalguna, P. S., Dattaguru V. Kamat, and P. V. Ananda Mohan. "RNS-To-Binary converters for New Three-moduli sets {2k, 2k-1, 2k(2k-1)+ 1} and {2k, 2k-1, 2k(2k-1)-1}." In 2019 IEEE Asia Pacific Conference on Postgraduate Research in Microelectronics and Electronics (PrimeAsia). IEEE, 2019. http://dx.doi.org/10.1109/primeasia47521.2019.8950699.

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6

McLaughlin, James E. "A Qualitative Risk-Based Assessment Procedure for High Temperature Hydrogen Attack of C-1/2Mo Steel." In ASME 2007 Pressure Vessels and Piping Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/pvp2007-26129.

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A qualitative risk-based assessment procedure was developed to determine the relative probability of failure for high temperature hydrogen attack (HTHA) of C-1/2Mo steel. It is well documented that C-1/2Mo possesses a variable resistance to HTHA. Over the years, the Nelson curve limits, as published in API RP 941, Steels for Hydrogen Service at Elevated Temperatures and Pressures in Petroleum Refineries and Petrochemical Plants, have been significantly reduced since originally published. This has created a need for an assessment procedure to evaluate C-1/2 Mo equipment that was designed many years ago when the Nelson curve was at much higher operating conditions than today. This assessment procedure is based on the current ExxonMobil assignment of C-1/2Mo resistance to HTHA on the Nelson curve and the relative dependence of HTHA on temperature, hydrogen partial pressure and time. We use the Pv relationship that appears in literature to define the relative dependence of HTHA on temperature, hydrogen partial pressure and time. This qualitative assignment of probability levels for HTHA was validated against actual HTHA failures of C-1/2Mo in high temperature hydrogen service that have been reported to the API and other internal Company incidents not reported to API. This assessment procedure is used to qualitatively define the probability of failure consistent with the probability levels defined in the ExxonMobil risk matrix which is used to manage all risk based decisions in the Corporation.
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Zhang, Liming, Kun Zhang, Hong Zhao, Kuiyan Song, Rufeng Sun, Yitao Fang, Chen Zhu, Dayong Zhang, Nianjiang Chen, and Shouhuan Zhou. "2kW narrow linewidth all fiber laser." In 24th National Laser Conference & Fifteenth National Conference on Laser Technology and Optoelectronics, edited by Yue Yang, Jianqiang Zhu, Weibiao Chen, Pu Wang, Jianrong Qiu, Zhenxi Zhang, and Minlin Zhong. SPIE, 2020. http://dx.doi.org/10.1117/12.2587636.

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8

Tatanto, Dedy, and Edy Tri Baskoro. "On Ramsey (2K2, 2Pn)-minimal graphs." In THE 5TH INTERNATIONAL CONFERENCE ON RESEARCH AND EDUCATION IN MATHEMATICS: ICREM5. AIP, 2012. http://dx.doi.org/10.1063/1.4724122.

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9

Tryggestad, E. "Low-Lying Dipole Strength In 20O." In FRONTIERS OF NUCLEAR STRUCTURE. AIP, 2003. http://dx.doi.org/10.1063/1.1556656.

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10

Zhan, Huan, Yuying Wang, Kun Peng, Li Ni, Xiaolong Wang, Jianjun Wang, Feng Jing, and Aoxiang Lin. "2kW (2+1) GT-wave fiber." In Optical Fiber Communication Conference. Washington, D.C.: OSA, 2016. http://dx.doi.org/10.1364/ofc.2016.w3e.2.

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Звіти організацій з теми "2KO":

1

Pronk, A. G., P. W. B. Friske, S. J. Day, and M. W. McCurdy. Regional stream sediment ant water data, northwestern New Brunswick, NTS 21O/11 and parts of 21O/10, 21O/14, 21O/15 and 21O/16. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1998. http://dx.doi.org/10.4095/209919.

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Henestroza, Enrique. Sensitivity Analysis of the DARHT-II 2.5MV/2kA Diode. Office of Scientific and Technical Information (OSTI), December 2006. http://dx.doi.org/10.2172/928866.

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Dumont, R., and J. Potvin. Residual total magnetic field, 21O/16 - Charlo, New Brunswick. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2005. http://dx.doi.org/10.4095/220933.

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Dumont, R., and J. Potvin. Residual total magnetic field, 21O/15 - Atholville, New Brunswick - Quebec. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2005. http://dx.doi.org/10.4095/220931.

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Brown-Shaklee, Harlan James. Bead Blasting Contamination of as Machined Ti-6Al-2Sn-4Zr-2Mo. Office of Scientific and Technical Information (OSTI), December 2014. http://dx.doi.org/10.2172/1173196.

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Hornbrook, E. H. W., and P. W. B. Friske. Regional stream sediment and water geochemical reconnaissance data, New Brunswick [21O/3]. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1989. http://dx.doi.org/10.4095/130701.

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Dumont, R., and J. Potvin. Second vertical derivative of the magnetic field, 21O/16 - Charlo, New Brunswick. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2005. http://dx.doi.org/10.4095/220936.

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SUE, Sistema Universitario Estatal. 2do Seminario Internacional: Evaluación de la implementación del acuerdo de paz. Memorias. Universidad Tecnológica de Pereira, 2021. http://dx.doi.org/10.22517/28056574.

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Анотація:
Este segundo Seminario Internacional de evaluación de la implementación del Acuerdo de Paz entre el Gobierno Nacional y las FARC se realizó en medio de una movilización de estudiantes y profesores de las universidades públicas que paralizó durante más de dos meses la educación superior estatal y que finalmente permitió un acuerdo sin antecedentes. Como estaba previsto, este Seminario se ocupó de atender, esencialmente el análisis de los avances y dificultades de la implementación de dicho Acuerdo que en 2018 sobrevivió en medio de aguas turbulentas. En efecto, durante el año de referencia, al tiempo que se realizaron elecciones parlamentarias y dos vueltas para la elección presidencial, en el país se realizó la consulta popular contra la corrupción. Aunque los once millones y medio de ciudadanos que participaron en dicha jornada democrática no fueron suficientes para superar el umbral, quedó claro que en la agenda pública nacional el tema es de prioridad inequívoca. Se debe confiar en ...
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Davis, V. A., and M. J. Mandell. Spacecraft Charging Modeling - Nascap-2k. Fort Belvoir, VA: Defense Technical Information Center, September 2012. http://dx.doi.org/10.21236/ada576395.

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Dumont, R., and J. Potvin. Second vertical derivative of the magnetic field, 21O/15 - Atholville, New Brunswick - Quebec. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2005. http://dx.doi.org/10.4095/220935.

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