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Статті в журналах з теми "Cellular tests"

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Автор: Grafiati

Опубліковано: 10 травня 2022

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1

Vaganov, A. A., A. S. Timonin, and I. I. Sidelnikov. "Hydraulic tests of cellular packing." Chemical and Petroleum Engineering 46, no. 11-12 (March 2011): 699–702. http://dx.doi.org/10.1007/s10556-011-9405-2.

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2

Chirumbolo, Salvatore. "Immunotherapy in allergy and cellular tests." Human Vaccines & Immunotherapeutics 10, no. 6 (May 2, 2014): 1595–610. http://dx.doi.org/10.4161/hv.28592.

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3

Ariza, Adriana, Maria Montanez, Tahia Fernandez, James Perkins, and Cristobalina Mayorga. "Cellular Tests for the Evaluation of Drug Hypersensitivity." Current Pharmaceutical Design 22, no. 45 (January 17, 2017): 6773–83. http://dx.doi.org/10.2174/1381612822666161107165917.

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4

Sanz, Maria, Pedro Gamboa, and A. De Weck. "Cellular Tests in the Diagnosis of Drug Hypersensitivity." Current Pharmaceutical Design 14, no. 27 (September 1, 2008): 2803–8. http://dx.doi.org/10.2174/138161208786369722.

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5

Dowling, V. P., and K. G. Martin. "Radiant Panel Fire Tests on Cellular Plastics Insulation." Journal of Thermal Insulation 8, no. 4 (April 1985): 314–38. http://dx.doi.org/10.1177/109719638500800407.

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6

Vaganov, A. A., and A. S. Timonin. "Heat- and mass-transfer tests of cellular packing." Chemical and Petroleum Engineering 46, no. 11-12 (March 2011): 686–91. http://dx.doi.org/10.1007/s10556-011-9402-5.

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7

Bathgate, AJ, JN Plevris, MM Dollinger, and PC Hayes. "Skin tests predict acute cellular rejection in liver transplantation." Gastroenterology 114 (April 1998): A1209. http://dx.doi.org/10.1016/s0016-5085(98)84907-x.

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8

Bathgate, A. J., J. N. Plevris, M. M. Dollinger, and P. C. Hayes. "SKIN TESTS PREDICT ACUTE CELLULAR REJECTION IN LIVER TRANSPLANTATION." Transplantation 67, no. 7 (April 1999): S260. http://dx.doi.org/10.1097/00007890-199904150-01038.

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9

Sabovljev, S. A., W. A. Cramp, P. D. Lewis, G. Harris, KeithE Halnan, and J. Lambert. "USE OF RAPID TESTS OF CELLULAR RADIOSENSITIVITY IN RADIOTHERAPEUTIC PRACTICE." Lancet 326, no. 8458 (October 1985): 787. http://dx.doi.org/10.1016/s0140-6736(85)90674-9.

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10

Buyuktiryaki, Betul, and Alexandra F. Santos. "Food allergy severity predictions based on cellular in vitro tests." Expert Review of Molecular Diagnostics 20, no. 7 (July 2, 2020): 679–91. http://dx.doi.org/10.1080/14737159.2020.1782192.

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11

Petrides, Michael. "Use of cellular telephones and performance on tests of attention." Neuroreport 12, no. 4 (March 2001): A21. http://dx.doi.org/10.1097/00001756-200103260-00001.

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12

Avalle, Massimiliano, Giovanni Belingardi, and Andrea Ibba. "Mechanical models of cellular solids: Parameters identification from experimental tests." International Journal of Impact Engineering 34, no. 1 (January 2007): 3–27. http://dx.doi.org/10.1016/j.ijimpeng.2006.06.012.

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13

SCOTT, A. "Ophthalmology (Picture Tests)." British Journal of Ophthalmology 82, no. 10 (October 1, 1998): 1220f. http://dx.doi.org/10.1136/bjo.82.10.1220f.

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14

Doig, W. M. "Clinical Tests: Ophthalmology." British Journal of Ophthalmology 75, no. 3 (March 1, 1991): 192. http://dx.doi.org/10.1136/bjo.75.3.192-a.

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15

Röhmel, J., C. Schwarz, D. Staab, and P. Stock. "119 Cellular allergy tests for antibiotic drug hypersensitivity in cystic fibrosis." Journal of Cystic Fibrosis 14 (June 2015): S87. http://dx.doi.org/10.1016/s1569-1993(15)30296-4.

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16

Scherer, Kathrin, Andreas J. Bircher, and Ingmar AFM Heijnen. "Diagnosis of stinging insect allergy: utility of cellular in-vitro tests." Current Opinion in Allergy and Clinical Immunology 9, no. 4 (August 2009): 343–50. http://dx.doi.org/10.1097/aci.0b013e32832dd1f5.

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17

Polienova, E. V., K. P. Makeeva, and A. Yu Valdberg. "Aerodynamic tests of new regular cellular packings for mass-transfer towers." Chemical and Petroleum Engineering 46, no. 11-12 (March 2011): 692–95. http://dx.doi.org/10.1007/s10556-011-9403-4.

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18

Durif, S., A. Bouchaïr, and O. Vassart. "Experimental tests and numerical modeling of cellular beams with sinusoidal openings." Journal of Constructional Steel Research 82 (March 2013): 72–87. http://dx.doi.org/10.1016/j.jcsr.2012.12.010.

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19

Fry, Jeffrey R., and Alison H. Hammond. "Assessment of the Functional Integrity of Hepatocytes: A Brief Review." Alternatives to Laboratory Animals 21, no. 3 (July 1993): 324–29. http://dx.doi.org/10.1177/026119299302100303.

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Анотація:

A variety of approaches to assessment of cellular integrity exist, based on tests of integrity of the plasma membrane, tests of metabolic competence, and asessment of morphology. By definition, such approaches address different aspects of cellular integrity and hence are not interchangeable indices of cellular integrity. Accordingly, it would be most appropriate to characterise hepatocyte preparations on the basis of more than just trypan blue dye exclusion (a test of plasma membrane integrity) as is customary. A scheme for the choice of the most appropriate mix of tests of cellular integrity is presented.

20

Haag, F. C., A. F. Galio, and L. Schaeffer. "Uniaxial compression tests of aluminium foams." Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture 216, no. 4 (April 1, 2002): 633–36. http://dx.doi.org/10.1243/0954405021520148.

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Some cellular aluminium materials have been extensively developed and investigated in recent years. The potential for applying aluminium foams in lightweight construction is mainly based on the stiffness and impact absorption. Because of these characteristics, this work is based mainly on the uniaxial compression resistance of aluminium foam. The aluminium foam was formed with three different compaction presses to verify the influence on density and, subsequently, crushing resistance.

21

Kondo, Andrea Tiemi, and Andreza Alice Feitosa Ribeiro. "Regulatory considerations for Cellular Therapy." JOURNAL OF BONE MARROW TRANSPLANTATION AND CELLULAR THERAPY 3, no. 1 (April 24, 2022): 166. http://dx.doi.org/10.46765/2675-374x.2022v3n1p166.

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Advanced therapy products can be an alternative treatment for several disease. Manufacturing steps and product release are critical points to avoid unsafe use of products. Quality controls tests, manufacturing practice, safety testing and efficacy trials need to be properly accessed before releasing to patients. Regulatory system for cell therapy products determines guidelines for production, clinical trials and registration, considering risk-benefit ratios. This article aims to discuss main aspects of National Regulatory for advanced therapy products.

22

Lowe, J. G., J. S. Beck, R. Madhok, A. Gracie, J. H. Gibbs, R. C. Potts, G. D. Lowe, and C. D. Forbes. "Histometric studies on cellular infiltrates of tuberculin tests in patients with haemophilia." Journal of Clinical Pathology 42, no. 2 (February 1, 1989): 184–87. http://dx.doi.org/10.1136/jcp.42.2.184.

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23

Lowe, J. G., J. H. Gibbs, R. C. Potts, J. L. Stanford, and J. Swanson Beck. "Histometric studies on cellular infiltrates of tuberculin tests in patients with sarcoidosis." Journal of Clinical Pathology 44, no. 3 (March 1, 1991): 219–23. http://dx.doi.org/10.1136/jcp.44.3.219.

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24

Wood, P. R., L. A. Corner, J. S. Rothel, J. L. Ripper, T. Fifis, B. S. McCormick, B. Francis, et al. "A field evaluation of serological and cellular diagnostic tests for bovine tuberculosis." Veterinary Microbiology 31, no. 1 (April 1992): 71–79. http://dx.doi.org/10.1016/0378-1135(92)90142-g.

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25

Stronge, W. J., and V. P. W. Shim. "Microdynamics of Crushing in Cellular Solids." Journal of Engineering Materials and Technology 110, no. 2 (April 1, 1988): 185–90. http://dx.doi.org/10.1115/1.3226029.

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Lightweight, open-celled foams and honeycombs can exhibit deformation localization during static crushing as a result of buckling and plastic collapse of cell walls. Localization of deformation is a manifestation of strain-softening behavior that limits transmitted forces through these shock mitigating materials. Collision tests on two-dimensional cellular solids with strain-softening behavior reveal that with some microstructures, strain-rate effects can stabilize less compliant modes of deformation. When stabilization occurs, it amplifies the intensity of transmitted shocks.

26

Del Rosso, Stefano, and Lorenzo Iannucci. "On the Compressive Response of Polymeric Cellular Materials." Materials 13, no. 2 (January 18, 2020): 457. http://dx.doi.org/10.3390/ma13020457.

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This paper presents a series of compression tests performed on a variety of high performance lightweight cellular materials conventionally used in energy absorption applications. Compressive tests were performed over a range of strain rates with a universal testing machine and a single stage gas gun. Experimental results revealed a dependency of the mechanical properties on the polymeric precursor, density, infill topology and strain rates. The dynamic strength of the investigated materials was determined through a material parameter identification study via the finite element (FE) method. Numerical results matched well with the experimental results and revealed a substantial enhancement in the compressive strength of the tested material from quasi-static to dynamic loading regimes by as much as 87%. The strength of 3D printed polymers was superior with respect to the tested polymeric foams. On the other hand, polymeric foams showed higher efficiency and energy absorption ability.

27

TAN, SYN KIAT, and SHENG-UEI GUAN. "A TRANSFORMATION SEQUENCING APPROACH TO PSEUDORANDOM NUMBER GENERATION." International Journal of Modern Physics C 18, no. 08 (August 2007): 1293–302. http://dx.doi.org/10.1142/s0129183107011327.

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This paper presents a new approach to designing pseudorandom number generators based on cellular automata. Current cellular automata designs either focus on (i) ensuring desirable sequence properties such as maximum length period, balanced distribution of bits and uniform distribution of n-bit tuples, etc. or (ii) ensuring the generated sequences pass stringent randomness tests. In this work, important design patterns are first identified from the latter approach and then incorporated into cellular automata such that the desirable sequence properties are preserved like in the former approach. Preliminary experiment results show that the new cellular automata designed have potential in passing all DIEHARD tests.

28

Son, Chang-Nam, and Sang-Hyon Kim. "Interpretation of Anti-Nuclear Antibody Tests." Korean Journal of Medicine 96, no. 4 (August 1, 2021): 337–40. http://dx.doi.org/10.3904/kjm.2021.96.4.337.

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Anti-nuclear antibodies (ANAs) are autoantibodies against nuclear substances or other cellular components. ANA tests are used in the diagnostic process to screen patients with suspected rheumatic or autoimmune diseases. ANA-associated diseases are characterized by a high titer of antinuclear antibodies and include systemic lupus erythematosus, systemic sclerosis, and mixed connective tissue diseases. ANA test results must be cautiously interpreted as they can be positive not only in infections and oncological diseases but also for the healthy general population. The ANA test mainly uses the indirect immunofluorescence test, and the results are expressed in terms of the final titer and pattern. The ANA test can increase diagnostic value when used in conjunction with the evaluation of disease-related clinical symptoms.

29

Mïller, Mathias. "Cellular diagnostics: A challenge for laboratory medicine." Jugoslovenska medicinska biohemija 23, no. 3 (2004): 195–200. http://dx.doi.org/10.2298/jmh0403195m.

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Investigating cells for genetic features, malignant transformation, surface characteristics, metabolic functions and signaling will be future key elements for diagnosis of diseases. Integrating this new area into Laboratory Medicine will add new competence and responsibility to Clinical Biochemistry and Laboratory Medicine. Cellular genetics will be a main area for the diagnostic laboratory to investigate risk and prognosis for diseases having also impact on a more individualized medication. With the introduction of flow cytometry a more objective way of cell identification by immunophenotyping was added to classical microscopy allowing accurate classification of leukaemias. In addition the functional status and the origin of blood cells or cells in other body fluids (liquor, ascites) can now easily be detected. Cell mediated immunity plays an important role in infectious diseases and in transplantation medicine. The CD4/CD8 ratio of T-lymphocytes is already a routine test for differentiation between viral infection and rejection crises and for monitoring of these conditions. In cellular coagulation platelet function tests will add value to the established plasma tests. The dosage of drugs is now monitored by measuring the blood levels of drugs or their metabolites. In addition investigating the direct effect of drugs on targeted cell functions might be a more specific way.

30

Ringle, Steven P. "Specific tests for polymyositis." Muscle & Nerve 13, S1 (1990): S40—S42. http://dx.doi.org/10.1002/mus.880131313.

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31

Kurcheva, S. A., D. A. Kovalev, D. G. Ponomarenko, Yu V. Siritsa, M. V. Kostyuchenko, A. G. Koshkid’ko, I. V. Zharnikova, E. L. Rakitina, O. V. Logvinenko, and A. M. Zhirov. "Qualitative Indicators of Experimental Brucellosis Antigen Preparations Designed for Cellular Tests in vitro." Problems of Particularly Dangerous Infections, no. 3 (October 22, 2020): 83–88. http://dx.doi.org/10.21055/0370-1069-2020-3-83-88.

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In order to develop the most diagnostically informative methods for carrying out antigen-stimulated cellular tests in vitro a careful selection of stimulating agent (antigen) is required, possessing an adequate activating potential and providing specificity of the reaction.Objective of the study was to identify the qualitative indicators of experimental batches of brucellosis antigen preparations designed for cellular tests in vitro.Materials and methods. Initially we produced antigen complexes of brucellosis microbe on the basis of the vaccine strains of three epidemically significant Brucella species (B. abortus, B. melitensis, B. suis). Quantitative determination of WsAg and PPBC proteins of experimental preparation series was performed applying capillary electrophoresis. Qualitative composition was assessed through ion exchange liquid chromatography with refractometric detection.Results and discussion. We have specified physical-chemical features, investigated chromatographic profiles and composition of protein fractions, as well as tried the produced experimental batches of brucellosis antigen preparations. After analyzing the defined protein and polysaccharide composition of the obtained WsAg samples, one can conclude that WsAg preparation cannot be used for cellular tests as the probability of non-specific lymphocyte reaction manifestation in vitro was experimentally proven. By contrast, complex brucellosis antigen preparation PPBC has an expressed specific activity and specificity under in vitro conditions and the prospects to be used when developing methodological approaches for laboratory diagnosis of brucellosis and assessment of de facto immunity rate in risk contingents after vaccination. The obtained parameters will allow for proper quality provision when manufacturing the developed experimental PPBC preparation designed for cellular tests in vitro, taking into account modern validation and standardization regulations.

32

Tong, Charles C., Charlene A. McQueen, Sharma Ved Brats, and Gary M. Williams. "The lack of genotoxicity of sodium fluoride in a battery of cellular tests." Cell Biology and Toxicology 4, no. 2 (June 1988): 173–86. http://dx.doi.org/10.1007/bf00119244.

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33

Moreno-Garrido, I., L. M. Lubián, and A. M. V. M. Soares. "Influence of Cellular Density on Determination of EC50 in Microalgal Growth Inhibition Tests." Ecotoxicology and Environmental Safety 47, no. 2 (October 2000): 112–16. http://dx.doi.org/10.1006/eesa.2000.1953.

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34

Israeli, Moshe, Tuvia Ben-Gal, Vicktoria Yaari, Andrei Valdman, Israel Matz, Benjamin Medalion, Alexander Battler, Benjamin Sredni, Don Kristt, and Tirza Klein. "Individualized Immune Monitoring of Cardiac Transplant Recipients by Noninvasive Longitudinal Cellular Immunity Tests." Transplantation 89, no. 8 (April 2010): 968–76. http://dx.doi.org/10.1097/tp.0b013e3181cbabe6.

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35

Demko, J. A., J. E. Fesmire, J. Dookie, J. Bickley, and S. Kraft. "Comparison tests of cellular glass insulation for the development of cryogenic insulation standards." IOP Conference Series: Materials Science and Engineering 101 (December 18, 2015): 012016. http://dx.doi.org/10.1088/1757-899x/101/1/012016.

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36

Debray, Julien, Lei Chang, Stéphanie Marquès, Stéphane Pellet-Rostaing, Do Le Duy, Saida Mebarek, René Buchet, David Magne, Florence Popowycz, and Marc Lemaire. "Inhibitors of tissue-nonspecific alkaline phosphatase: Design, synthesis, kinetics, biomineralization and cellular tests." Bioorganic & Medicinal Chemistry 21, no. 24 (December 2013): 7981–87. http://dx.doi.org/10.1016/j.bmc.2013.09.053.

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37

Ergenc, Ali Fuat, та Nejat Olgac. "New technology for cellular piercing: rotationally oscillating μ-injector, description and validation tests". Biomedical Microdevices 9, № 6 (21 липня 2007): 885–91. http://dx.doi.org/10.1007/s10544-007-9102-2.

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38

Pedersen, Morten Gram, Gianna M. Toffolo, and Claudio Cobelli. "Cellular modeling: insight into oral minimal models of insulin secretion." American Journal of Physiology-Endocrinology and Metabolism 298, no. 3 (March 2010): E597—E601. http://dx.doi.org/10.1152/ajpendo.00670.2009.

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The oral glucose tolerance test and meal tolerance test are common clinical tests of the glucose-insulin system. Several mathematical models have been suggested as means to extract information about β-cell function from data from oral tolerance tests. Any such model needs to be fairly simple but should at the same time be linked to the underlying biology of the insulin-secreting β-cells. The scope of the present work is to present a way to make such a connection using a recent model describing intracellular mechanisms. We show how the three main components of oral minimal secretion models, derivative control, proportional control, and delay, are related to subcellular events, thus providing mechanistic underpinning of the assumptions of the minimal models.

39

Eberlein-König, Bernadette, and Johannes Ring. "Diagnosis of IgE-mediated hymenoptera venom anaphylaxis in patients with negative skin tests and negative RAST using cellular in vitro tests." Journal of Allergy and Clinical Immunology 113, no. 6 (June 2004): 1223. http://dx.doi.org/10.1016/j.jaci.2004.01.770.

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40

Kishimoto, Satoshi. "Closed Cellular Materials for Smart Materials." Materials Science Forum 638-642 (January 2010): 2074–79. http://dx.doi.org/10.4028/www.scientific.net/msf.638-642.2074.

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New methods to fabricate a metallic closed cellular material for smart materials using an isostatic pressing and penetrating method are introduced. Powder particles of polymer or ceramics coated with a metal layer using electro-less plating were pressed into pellets and sintered at high temperature. These powder particles were sintered by spark plasma sintering (SPS) method. Closed cellular materials including polymer were fabricated by penetrating polymer into metallic foams. Many kinds of metallic closed cellular materials including different materials from that of cell walls were tried to fabricate. The physical and mechanical properties of these materials were measured. The results of the compressive tests show that this material has high-energy absorption and the result of measuring the internal friction show that the internal friction of these materials is larger than that of pure aluminum.

41

Chicos, Lucia-Antoneta, Ian Campbell, Sebastian Marian Zaharia, Mihai Alin Pop, Camil Lancea, Augustin Semenescu, Bogdan Florea, and Oana Roxana Chivu. "Experimental and Finite Element Analysis of the Open-Cells Porous Materials Subjected to Compression Mechanical Loading." Materiale Plastice 56, no. 2 (June 30, 2019): 421–25. http://dx.doi.org/10.37358/mp.19.2.5199.

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Progress in Additive Manufacturing (AM) technology enables the fabrication of complex structures that could not be obtained with traditional manufacturing methods. One AM research area is the development and use of lightweight products with cellular structures, containing complex lattices and pores, which give improved performance and functionality. It is well known that there is a strong link between mechanical properties and architecture of samples with cellular structures. This paper presents a comparison and validation of Finite Element Analysis (FEA) simulations of cellular structures with experimental data obtained from compression tests, and degradation behaviour under load compression. The specimens, with spherical open-cells, were produced in VeroClear RGD810 photopolymer resin. Mechanical compression tests were performed to investigate the compressive behaviour and the mechanical response was registered in the form of compressive stress-strain curves. Also, using the specimens� CAD data and compression test parameters, a Finite Element Analysis (FEA) was performed. A macroscopic analysis of the specimens� structure and microhardness tests before and after compression tests were also carried out.

42

Fava-Netto, Celeste, Walderez Gambale, Júlio Croce, Claudete R. Paula, and Sérgio de C. Fava. "Candidin: comparison of two antigens for cutaneous delayed hypersensitivity testing." Revista do Instituto de Medicina Tropical de São Paulo 38, no. 6 (December 1996): 397–99. http://dx.doi.org/10.1590/s0036-46651996000600002.

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A candidin, which is a suspension of killed yeast cells, is commonly used for intradermal tests of delayed hypersensitivity, to evaluate the immunological cellular competence of the patient, when the test is applied along with other similar tests. When working with a cellular antigen, the histopathology of positive skin tests reveals a cellular infiltrate which not only presents a characteristic hypersensitivity reaction but also a neutrophilic abscess in the central part. This research presents the results of a comparison between the yeast cell suspension and the polysaccharide antigens, both obtained from the same strains of Candida albicans. The results obtained by skin tests in one hundred individuals were 61.0% with the polysaccharide antigen and 69.0% with the yeast cell suspension antigen. Concordant results concerning the two antigens were observed in 82.0% of the individuals. The discussion section presents an assumption to explain the differences of positivity obtained with the two antigens. We conclude that the polysaccharide antigen can be utilized in the intradermal test of delayed hypersensitivity to Candida albicans.

43

Koss-Mikołajczyk, Izabela, Monika Baranowska, Jacek Namieśnik, and Agnieszka Bartoszek. "Determination of antioxidantactivity of phytochemicals in cellular models by fluorescence/luminescence methods." Postępy Higieny i Medycyny Doświadczalnej 71, no. 1 (July 30, 2017): 0. http://dx.doi.org/10.5604/01.3001.0010.3841.

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As soon as the role of Reactive Oxygen Species (ROS) in so-called civilization diseases, which include non-infectious chronic diseases such as cancer, diabetes or high blood pressure has been discovered, and the possibility of employing antioxidants as a remedy for these diseases have been proposed, scientists developed a broad spectrum of methods to determine antioxidant activity of pure chemicals and plant extracts, as well as dietary supplements. Most of these methods are based on simple redox reactions between antioxidant and ROS (for example ABTS, DPPH, or FRAP tests). However, chemical methods of assessing antioxidant activity are rarely biologically relevant. They do not mirror the real effect of antioxidants in living organisms, because they are used in non-physiological conditions of temperature and pH; neither they take metabolism nor intracellular transport under consideration. The perfect model for assessment of antioxidant activity in living organisms would be human or animal model, but such determinations are very complicated and often ambiguous. The current best alternative to chemical and human tests are assays employing cell culture models being less expensive than human tests, yet still reflecting biological systems more convincingly than chemical assays. Cellular antioxidant assays are performed under physiological pH and temperature, but most importantly, they take metabolism and intracellular transport under consideration. In this review, we present cellular tests used to determine antioxidant activity that are based on luminescence and fluorescence methods.

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Spangenberg, P., and U. Till. "Actin filament content in platelets—A sensitive index of cellular reactivity." Bioscience Reports 9, no. 3 (June 1, 1989): 307–13. http://dx.doi.org/10.1007/bf01114683.

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Blood platelets have the capacity to participate in a number of physiological as well as pathological processes within the circulation. In order to evaluate their cellular reactivity a number of platelet function tests have been developed. The main in vitro function tests are assessment of aggregation and adhesion, secretion, arachidonate metabolism, coagulant activities and the characterization of surface membrane glycoproteins (Day and Rao, 1986). Here we measure alterations of the G-/F-actin equilibrium of platelets. High F-actin values of unstimulated platelets indicate a hyperreactivity of the cell as examined in platelets from diabetics. Determination of the actin filament content in platelets can be considered as a new sensitive function test.

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Oliveira, Monique Cristine de, and João Paulo Ferreira Schoffen. "Oxidative stress action in cellular aging." Brazilian Archives of Biology and Technology 53, no. 6 (December 2010): 1333–42. http://dx.doi.org/10.1590/s1516-89132010000600009.

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Various theories try to explain the biological aging by changing the functions and structure of organic systems and cells. During lifetime, free radicals in the oxidative stress lead to lipid peroxidation of cellular membranes, homeostasis imbalance, chemical residues formation, gene mutations in DNA, dysfunction of certain organelles, and the arise of diseases due to cell death and/or injury. This review describes the action of oxidative stress in the cells aging process, emphasizing the factors such as cellular oxidative damage, its consequences and the main protective measures taken to prevent or delay this process. Tests with antioxidants: vitamins A, E and C, flavonoids, carotenoids and minerals, the practice of caloric restriction and physical exercise, seeking the beneficial effects on human health, increasing longevity, reducing the level of oxidative stress, slowing the cellular senescence and origin of certain diseases, are discussed.

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Van Dijk, J. Gert. "Multiple tests and diagnostic validity." Muscle & Nerve 18, no. 3 (March 1995): 353–55. http://dx.doi.org/10.1002/mus.880180317.

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Hellweg, Christine E., Shahana Dilruba, Astrid Adrian, Sebastian Feles, Claudia Schmitz, Thomas Berger, Bartos Przybyla, et al. "Space experiment “Cellular Responses to Radiation in Space ( CellRad) ”: Hardware and biological system tests." Life Sciences in Space Research 7 (November 2015): 73–89. http://dx.doi.org/10.1016/j.lssr.2015.10.003.

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Lipowska, B., B. Psiuk, M. Cholewa, and Ł. Kozakiewicz. "Preliminary Tests of Cellular SiC/Iron Alloy Composite Produced by a Pressureless Infiltration Technique." Archives of Foundry Engineering 17, no. 1 (March 1, 2017): 115–20. http://dx.doi.org/10.1515/afe-2017-0021.

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Abstract Preliminary tests aimed at obtaining a cellular SiC/iron alloy composite with a spatial structure of mutually intersecting skeletons, using a porous ceramic preform have been conducted. The possibility of obtaining such a composite joint using a SiC material with an oxynitride bonding and grey cast iron with flake graphite has been confirmed. Porous ceramic preforms were made by pouring the gelling ceramic suspension over a foamed polymer base which was next fired. The obtained samples of materials were subjected to macroscopic and microscopic observations as well as investigations into the chemical composition in microareas. It was found that the minimum width of a channel in the preform, which in the case of pressureless infiltration enables molten cast iron penetration, ranges from 0.10 to 0.17 mm. It was also found that the ceramic material applied was characterized by good metal wettability. The ceramics/metal contact area always has a transition zone (when the channel width is big enough), where mixing of the components of both composite elements takes place.

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Fortunati, Elisabetta, and Vera Bianchi. "Spectrophotometric Determination of Total Macromolecules for the Evaluation of Cellular Density in Cytotoxicity Tests." Alternatives to Laboratory Animals 19, no. 1 (February 1991): 18–25. http://dx.doi.org/10.1177/026119299101900105.

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Variation of cell number in treated cultures relative to the controls is an indicator of toxicity frequently employed in cytotoxicity tests. Cell density is generally determined from the amount of macromolecular components (DNA, proteins) measured by colorimetric methods. Another established procedure is the neutral red (NR) uptake test, which, in principle, permits an evaluation of the amount of viable cells in the different samples. We have devised a simple method for comparing cell density in the cultures, based on the spectrophotometric determination of the total macromolecules present in the cell monolayers solubilised in alkali after removal of the soluble fraction (TM test). When applied in parallel with the NR assay in a cell viability assay, our TM test gives a concordant rank of toxic potency for the chemicals tested. In comparison with NR uptake, the TM method appears to be more accurate and the data it provides are less prone to variation.

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Ansoborlo, E., J. Chalabreysse, M. H. Hengé-Napoli, and E. Pujol. "In vitro chemical and cellular tests applied to uranium trioxide with different hydration states." Environmental Health Perspectives 97 (July 1992): 139–43. http://dx.doi.org/10.1289/ehp.9297139.

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