Добірка наукової літератури з теми "Enhancing bone ingrowth"

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Статті в журналах з теми "Enhancing bone ingrowth"

1

Wu, Vivian, Marco N. Helder, Nathalie Bravenboer, et al. "Bone Tissue Regeneration in the Oral and Maxillofacial Region: A Review on the Application of Stem Cells and New Strategies to Improve Vascularization." Stem Cells International 2019 (December 30, 2019): 1–15. http://dx.doi.org/10.1155/2019/6279721.

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Анотація:
Bone tissue engineering techniques are a promising alternative for the use of autologous bone grafts to reconstruct bone defects in the oral and maxillofacial region. However, for successful bone regeneration, adequate vascularization is a prerequisite. This review presents and discusses the application of stem cells and new strategies to improve vascularization, which may lead to feasible clinical applications. Multiple sources of stem cells have been investigated for bone tissue engineering. The stromal vascular fraction (SVF) of human adipose tissue is considered a promising single source f
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2

Pius, Alexa K., Masakazu Toya, Qi Gao, Yasemin Sude Ergul, Simon Kwoon-Ho Chow, and Stuart Barry Goodman. "Effects of Aging on Osteosynthesis at Bone–Implant Interfaces." Biomolecules 14, no. 1 (2023): 52. http://dx.doi.org/10.3390/biom14010052.

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Анотація:
Joint replacement is a common surgery and is predominantly utilized for treatment of osteoarthritis in the aging population. The longevity of many of these implants depends on bony ingrowth. Here, we provide an overview of current techniques in osteogenesis (inducing bone growth onto an implant), which is affected by aging and inflammation. In this review we cover the biologic underpinnings of these processes as well as the clinical applications. Overall, aging has a significant effect at the cellular and macroscopic level that impacts osteosynthesis at bone-metal interfaces after joint arthro
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3

Roy, Robert G., Mark D. Markel, Alan J. Lipowitz, Florian Gottsauner-Wolf, Howard F. Taswell, and Edmund Y. S. Chao. "Effect of homologous fibrin adhesive on callus formation and extracortical bone bridging around a porous-coated segmental endoprosthesis in dogs." American Journal of Veterinary Research 54, no. 7 (1993): 1188–96. http://dx.doi.org/10.2460/ajvr.1993.54.07.1188.

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Анотація:
Summary Modular, porous-coated, titanium segmental endoprostheses were implanted bilaterally in the femoral diaphysis of 7 adult mixed-breed dogs. Autogenous bone graft in particle form was placed around the implant and bone. In 1 limb, homologous fibrin adhesive was mixed with the graft in situ before soft tissue closure. The contralateral limb was grafted in identical manner, but without fibrin adhesive, and served as a control. Radiography was performed immediately after surgery and 1, 2, 3, 4, 6, 8, 10, and 12 weeks later to assess callus area and bone remodeling. At 12 weeks, dogs were eu
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4

Ko, S. Y., J. Y. Hong, W. Lee, Y. Y. Chang, K. B. Park, and J. H. Yun. "Osteoconductivity of Porous Titanium Structure on Implants in Osteoporosis." Journal of Dental Research 100, no. 10 (2021): 1178–85. http://dx.doi.org/10.1177/00220345211023724.

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Анотація:
In compromised bone conditions such as osteoporosis, developments of the implant surface are necessary to secure the stability of implants. This study investigated the effect of the surface porous titanium structure (PS) on the osseointegration of implants in osteoporotic bone. Bilateral ovariectomy (OVX) was performed in 4 female beagle dogs to induce osteoporosis for 32 wk. Success of induction was based on the evaluation of bone mineral density by Hounsfield units (HU) in computed tomography images. Posterior teeth in both mandibles were extracted 1 wk after OVX, and a total of 30 implants
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5

Cao, Peng, X. N. Zhang, D. L. Zhang, and Brian Gabbitas. "Mechanical Compatability of Nanostructured Titanium with Human Bone." Materials Science Forum 618-619 (April 2009): 307–10. http://dx.doi.org/10.4028/www.scientific.net/msf.618-619.307.

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Анотація:
With their very low density, excellent biocompatibility, and good mechanochemical properties, titanium alloys have been considered a high-end material for making biomedical devices and instruments. However, they still have some substantial challenges to be overcome. One major problem, which eventually leads to revision surgery, is the implant loosening- a result of tissue migration, formation of wear debris, insufficient interface bonding between bone and implant, and stress shielding. Nanosized features in the material have the potential to provide a solution to these problems. A nanostructur
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6

McCarthy, Colleen, and Gulden Camci-Unal. "Low Intensity Pulsed Ultrasound for Bone Tissue Engineering." Micromachines 12, no. 12 (2021): 1488. http://dx.doi.org/10.3390/mi12121488.

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Анотація:
As explained by Wolff’s law and the mechanostat hypothesis, mechanical stimulation can be used to promote bone formation. Low intensity pulsed ultrasound (LIPUS) is a source of mechanical stimulation that can activate the integrin/phosphatidylinositol 3-OH kinase/Akt pathway and upregulate osteogenic proteins through the production of cyclooxygenase-2 (COX-2) and prostaglandin E2 (PGE2). This paper analyzes the results of in vitro and in vivo studies that have evaluated the effects of LIPUS on cell behavior within three-dimensional (3D) titanium, ceramic, and hydrogel scaffolds. We focus speci
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7

Mohan, Saktiswaren, Puvanan Karunanithi, Malliga Raman Murali, et al. "Potential Use of 3D CORAGRAF-Loaded PDGF-BB in PLGA Microsphere Seeded Mesenchymal Stromal Cells in Enhancing the Repair of Calvaria Critical-Size Bone Defect in Rat Model." Marine Drugs 20, no. 9 (2022): 561. http://dx.doi.org/10.3390/md20090561.

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Анотація:
Our previous study evidenced that the 3D CORAGRAF loaded with PLGA microsphere constitutes PDGF-BB can support cell attachment and proliferation and can induce an osteogenic commitment of mesenchymal stromal cells in the in vitro condition. However, how this construct can perform in pathophysiological conditions in terms of repairing critical bone defects is yet to be understood. A study was therefore conducted to investigate the regeneration potential of calvaria critical-size defects using CORAGRAF + PLGA with PDGF-BB + mesenchymal stromal cells (MSCs) in a rat model. A 5 mm critical bone de
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8

Frieler, Sven, Carsten Gebert, Yannik Hanusrichter, Periklis Godolias, and Martin Wessling. "The Modified Harrington Procedure for Metastatic Peri-Acetabular Bone Lesion Using a Novel Highly Porous Titanium Revision Shell with Long Lever Arm Screw." Medicina 60, no. 7 (2024): 1047. http://dx.doi.org/10.3390/medicina60071047.

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Анотація:
Background and Objectives: Peri-acetabular metastases often lead to significant pain and functional impairment. Surgical interventions, including the Harrington procedure, aim to address these challenges. This study evaluates a modified Harrington procedure using the MUTARS® PRS® (Pelvic Revision Shell) with an 8 mm fixation screw for severe acetabular defects resulting from metastatic lesions. Materials and Methods: Retrospective analysis of 12 patients treated between January 2020 and December 2023 was conducted. The procedure involved using the novel MUTARS® PRS® with an 8 mm in diameter do
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9

Baggio, Ana M. P., Yannick M. Sillmann, Pascal Eber, et al. "How Does Ceramic-Based Scaffold Microarchitecture Impact Maxillofacial Bone Regeneration? A Systematic Review of Large Animal Models." Applied Sciences 15, no. 12 (2025): 6899. https://doi.org/10.3390/app15126899.

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Анотація:
Critical-sized bone defects (CSBDs) are injuries that exceed the body’s natural capacity for repair and require external intervention. These defects are particularly challenging in the mandible, often resulting from trauma, tumor resection, or implant-related complications. Effective treatment involves scaffold designs that support vascularization, bone formation, and sufficient mechanical strength. This systematic review aims to assess whether ceramic-based scaffold properties, including porosity, pore size, and macroscopic characteristics, improve vascularization, bone formation, and the mec
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10

Huang, Mao-Suan, Shang-Yang Yu, Pao-Chang Chiang, et al. "Effect of Mechanobiology of Cell Response on Titanium with Multilayered Aluminum Nitride/Tantalum Thin Film." Applied Sciences 10, no. 2 (2020): 645. http://dx.doi.org/10.3390/app10020645.

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Анотація:
In the present study, the piezoelectric aluminum nitride (AlN)/tantalum (Ta) (PAT) thin film was investigated as a biocompatible film and osseointegrated with biomedical devices such as implants. The stress variation on the interaction of cells with the PAT surface was investigated using osteoblast-like cells (MG-63) and fibroblast cells (NIH3T3). A singular behavior was observed on the PAT film with a (002) texture, in which the MG-63 cells were more dispersed and displayed longer and more filopodia than the NIH3T3 cells. Moreover, the MG-63 cells showed ingrowth, adherence, and proliferation
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