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Дисертації з теми "FTO gene"

Автор: Grafiati

Опубліковано: 3 червня 2025

Оновлено: 31 липня 2025

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1

Smajlovic, Dzenan. "Bestämning av FTO (Fat mass and obesity associated gene) polymorfism." Thesis, University of Kalmar, School of Pure and Applied Natural Sciences, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:hik:diva-804.

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<p>Vetenskapen har på senare år försökt fastställa de olika orsaker som leder till fetma. Det är känt att högt energiintag och för lite motion för eller senare hos de flesta individer resulterar i fetma. Det som kan konstateras är att ärftlighet i samspel med miljön vi lever i och påverkas av kan vara den huvudsakliga orsaken till en rad sjukdomar inklusive fetma. På senare år har forskare upptäckt olika gener som på ett eller annan sett är involverade i ämnesomsättningen. En sådan gen är ”fat mass and obesity associated gene”, FTO. Denna gen återfinns på kromosom 16 och har en storlek på 410

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2

Bitello, Adriana Regina. "Relação entre a dieta e o polimorfismo rs9939609 do gene FTO e a interação entre os marcadores bioquímicos e nutricionais." reponame:Repositório Institucional da UNIVATES, 2014. http://hdl.handle.net/10737/484.

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Submitted by FERNANDA DA SILVA VON PORSTER (fdsvporster@univates.br) on 2014-06-02T17:12:47Z No. of bitstreams: 3 license_text: 21393 bytes, checksum: 7c4ecb3427d83129a338fc10c55e726a (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) 2014AdrianaReginaBitello.pdf: 740341 bytes, checksum: 3038e78bbc36511e66c5eab91ca5e5f3 (MD5)<br>Approved for entry into archive by Ana Paula Lisboa Monteiro (monteiro@univates.br) on 2014-06-05T12:30:58Z (GMT) No. of bitstreams: 3 license_text: 21393 bytes, checksum: 7c4ecb3427d83129a338fc10c55e726a (MD5) license_rdf: 23148 bytes, ch

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3

Koni, Anna Christina. "Effects of the FTO gene and environment on obesity in European children." Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/4175/.

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Childhood obesity is considered to be one of the most serious public health problems of the 21st century. The worldwide prevalence of obesity has increased dramatically over the past three decades and while continuing to rise at a rapid rate, along with increasing levels of childhood obesity, are having a profound effect on healthcare development in many low- and middle-income countries, particularly in urban environments. Longitudinal and cross sectional studies have indicated clear associations between environment and obesity risk. In addition, childhood obesity leads to serious health condi

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4

Stasiak, Lukasz. "Functional analysis of the fat mass and obesity associated (Fto) gene and protein." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:74abbb87-26f6-423d-b231-2d910f707bcd.

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Genome wide association studies have shown that common variants in the human fat mass and obesity-associated (FTO) gene predispose to obesity and increased fat mass. Mice globally lacking Fto are lean, while mice globally overexpressing Fto have increased body weight due to increased fat mass. FTO protein was shown to localise to the nucleus and demethylate ssDNA and ssRNA. However, the mechanisms by which FTO mediates its effects on body phenotype remain unknown. In this thesis, I found that native FTO can be detected in both the nucleus and the cytoplasm during interphase, and that nuclear F

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5

Dietrich, Kerstin. "Molekulare Evolution der metabolisch relevanten Gene MTNR1B (Melatoninrezeptor 1B) und FTO (Fat Mass and Obesity Associated)." Doctoral thesis, Universitätsbibliothek Leipzig, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-104580.

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Die hier vorliegende Arbeit zeigt die molekulare Evolution des Melatoninrezeptor 1 B-Gens (MTNR1B) und des Fat Mass and Obesity Associated-Gens (FTO). Für beide Gene wurden in genomweiten Assoziationsstudien (GWAS) Varianten entdeckt, welche zu der Entwicklung einer Adipositas bzw. deren Folgeerkrankungen beitragen können. So wurde für Einzelbasenaustausche (SNPs) im MTNR1B (rs10830963, rs4753426) eine Verschlechterung der Nüchternglukose sowie der Insulinausschüttung gezeigt. Zudem wurde für die Allelfrequenz des rs4753426 C-Allels ein Zusammenhang mit der täglichen Sonnenscheindauer beschrie

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6

McMurray, Fiona. "Investigating the role of the fat mass and obesity associated gene (Fto) in obesity." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:d7b76f58-6206-47fc-a208-7eeefac7fe27.

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In 2007, a genome wide association study identified a SNP in intron 1 of FTO with increased BMI. Homozygous risk allele carriers are on average three kg heavier than those homozygous for the protective allele. Mouse models have been made, including a conditional knockout, which is lean when globally expressed, as well as a conditional overexpression allele, which has increased body weight when globally expressed. The results from these and other studies suggest that the FTO SNPs lead to weight gain by increasing FTO activity and/or expression. Adult inactivation of Fto using the tamoxifen indu

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7

Church, Christopher David. "Mouse models for the functional analysis of the fat mass and obesity associated gene FTO." Thesis, University of Oxford, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.534152.

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8

Borine, Meredith I. "Parenting Style Influences on Appetite Regulation in African American Children and the Effect of the FTO Gene." Master's thesis, Temple University Libraries, 2012. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/176039.

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Epidemiology<br>M.S.<br>Purpose: Indulgent parent feeding-styles have been associated with higher child body mass index (BMI); more direct influences on children's eating are not well characterized. This study examined whether African American (AA) children exhibited poorer appetite regulation when mothers had an indulgent feeding style relative to other feeding styles. This study also examined whether the FTO gene influenced the relationship between feeding style and appetite regulation. Methods: An observational design was used to evaluate the association of maternal feeding styles with chil

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9

Ronkainen, J. (Justiina). "Role of Fto in the gene and microRNA expression of mouse adipose tissues in response to high-fat diet." Doctoral thesis, Oulun yliopisto, 2016. http://urn.fi/urn:isbn:9789526213453.

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Abstract Obesity is associated with greater risk of several diseases, such as type 2 diabetes and metabolic syndrome. Single nucleotide polymorphisms (SNP) within the fat mass- and obesity-associated gene FTO are robustly associated with increased body mass index (BMI) in several age and ethnic groups. Studies with transgenic mice support a mechanistic role for FTO protein in energy metabolism. Fto-deficient mice are leaner than wild-type and overexpression of Fto leads to obese phenotype; however, the precise mechanism of FTO action in the control of BMI has remained obscure. Fto mRNA is most

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10

Ramos, Ramon Bossardi. "Gene ligado a obesidade e massa gorda (fat mass and obesity associated; fto), menopausa e fatores de risco cardiovascular em mulheres na pós-menopausa." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2011. http://hdl.handle.net/10183/30937.

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Obesidade é uma doença crônica multifatorial que no Brasil atinge cerca de 12,4% dos homens e 16,9% das mulheres com mais de 20 anos. No período pós menopáusico, as mulheres apresentam uma série de alterações fisiológicas, entre elas alteração na distribuição de gordura corporal, sobretudo um aumento na região abdominal. A obesidade apresenta uma etiologia poligênica e diversos genes vêm sendo estudados, entre eles o gene ligado a obesidade e massa gorda (FTO) que já se mostrou fortemente associado com a obesidade/IMC. Mas em relação a parâmetros metabólicos e marcadores de risco cardiovascula

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11

Berulava, Tea [Verfasser], Bernhard [Akademischer Betreuer] Horsthemke, Anke [Akademischer Betreuer] Hinney, and Ulrich [Akademischer Betreuer] Rüther. "Expression and function of the fat mass and obesity-associated gene FTO / Tea Berulava. Gutachter: Bernhard Horsthemke ; Anke Hinney ; Ulrich Rüther. Betreuer: Bernhard Horsthemke." Duisburg, 2013. http://d-nb.info/1035066386/34.

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12

Sarter, Michael [Verfasser], Payam [Gutachter] Akhyari, and Thomas [Gutachter] Höhn. "Einfluss des Fto-Gens (fat mass and obesity-associated gene) auf degenerative Prozesse in bovinem Glutaraldehyd-fixiertem Herzklappen-Bioprothesenmaterial in einem Knockout-Mausmodell / Michael Sarter ; Gutachter: Payam Akhyari, Thomas Höhn." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2020. http://d-nb.info/1205969470/34.

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13

Dietrich, Kerstin [Verfasser], Peter [Akademischer Betreuer] Kovacs, Michael [Akademischer Betreuer] Stumvoll, and Unbekannt [Gutachter] Unbekannt. "Molekulare Evolution der metabolisch relevanten Gene MTNR1B (Melatoninrezeptor 1B) und FTO (Fat Mass and Obesity Associated) / Kerstin Dietrich ; Gutachter: Unbekannt Unbekannt ; Peter Kovacs, Michael Stumvoll." Leipzig : Universitätsbibliothek Leipzig, 2013. http://d-nb.info/1238242472/34.

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14

Steemburgo, Thais. "Interação gene e nutriente em pacientes com diabete melito tipo 2 : aspectos relacionados às complicações crônicas do diabetes, síndrome metabólica e efeitos dos polimorfismos rs9939609 (A/T) e rs7204609 (CT) do gene do FTO." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2009. http://hdl.handle.net/10183/16853.

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15

Brito, Ema C. "Gene x lifestyle interactions in type 2 diabetes mellitus and related traits." Doctoral thesis, Umeå : Umeå University, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-30523.

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16

Moraes, Tamiris Invencioni. "Relação entre polimorfismos dos genes LEP, FTO, APOA5, ADRB3, TCF7L2, ENPP1, CYP11B2 e PPARG e a síndrome metabólica." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-01072015-121645/.

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A síndrome metabólica (SM) é um conjunto de alterações metabólicas caracterizadas por três de cinco fatores sendo estes; obesidade abdominal, resistência à insulina, hiperglicemia, dislipidemia e hipertensão. As alterações fisiopatológicas da SM são importantes fatores de risco para a doença cardiovascular que tem alta prevalência na maioria das populações. Estudos genéticos têm mostrado que polimorfismos em genes envolvidos em vias do metabolismo glicídico e lipídico estão relacionados com maior predisposição à SM, porém há poucos dados na nossa população. O objetivo deste projeto é estudar a

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17

Mao, Söderberg Mao. "Clinical Pharmacogenetics of Olanzapine : with Focus on FMO Gene Polymorphisms." Doctoral thesis, Uppsala universitet, Klinisk farmakogenomik och osteoporos, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-179957.

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Pharmacogenetics is the study of variability in drug response attributed to genetic variation. Olanzapine (OLA) is a widely used antipsychotic drug for schizophrenia treatment. The pharmacokinetics of OLA display large inter-individual variation leading to multiple-fold differences in drug exposure between patients at a given dose. This variation in turn gives rise to the need of individualized dosing in order to avoid concentration-dependent adverse effects and therapeutic failure. The observed variability has been partially explained by environmental and physiological factors. Genetically de

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18

Procter, Catherine M. "The roles of the FRO genes in iron metabolism." Thesis, University of Newcastle Upon Tyne, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313219.

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19

Sadjuga. "Regulation of ferric-chelate reductase activity and the FRO gene family of Arabidopsis thaliana." Thesis, University of Newcastle Upon Tyne, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311143.

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20

Bester, Michael Christiaan. "The control of cellular adhesion of Saccharomyces cerevisiae by the FLO gene regulator Mss11p." Thesis, Stellenbosch : University of Stellenbosch, 2010. http://hdl.handle.net/10019.1/4026.

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Thesis (PhD (Science) (Viticulture and Oenology. Wine Biotechnology))--University of Stellenbosch, 2010.<br>ENGLISH ABSTRACT: The yeast Saccharomyces cerevisiae senses change within its environment and responds through specific adaptive cellular programmes, in particular by modifying gene expression. Many adaptive changes affect the physico-chemical properties of the cell wall, and several mechanisms that specifically affect the expression levels of genes that encode for cell wall components have been described previously. Cell wall modification directly impacts on general cell wall prope

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21

Hoang, Ngoc-Anh S. "Tissue specific effects of [beta]FTZ-F1 loss-of-function on the early gene E93 transcription during Drosophila melanogaster metamorphosis /." Connect to online version, 2006. http://ada.mtholyoke.edu/setr/websrc/pdfs/www/2006/140.pdf.

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22

Islam, Riswana. "The role of [beta]FTZ-F1 in the innervation of the abdominal and pharyngeal muscles in Drosophila /." Connect to online version, 2005. http://ada.mtholyoke.edu/setr/websrc/pdfs/www/2005/92.pdf.

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23

Furlan, Giulia. "Investigating the contribution of the non-coding gene Ftx to X-chromosome inactivation in mammals." Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCC191/document.

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L’inactivation du chromosome X (XCI) est un mécanisme qui permet l’extinction transcriptionelle d’un des deux chromosomes X chez la femelle. XCI est régulé par une région spécifique nommée centre de l’inactivation du chromosome (Xic), contenant plusieurs gènes produisant de longs ARNs non codants (lncRNAs). Parmi ces lncRNAs, le transcrit Xist est l’effecteur principal pour l’XCI. Xist peut s’accumuler en cis sur le chromosome et recruter la machinerie qui permettra l’initiation et la propagation de l’extinction transcriptionnelle à l’échelle du chromosome.Le laboratoire d’accueil a identifié

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24

Andreu, Cervera Abraham. "Role of the ciliopathy gene Ftm/Rpgrip1l and primary cilia in forebrain patterning and morphogenesis." Electronic Thesis or Diss., Sorbonne université, 2018. http://www.theses.fr/2018SORUS223.

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Les cils primaires sont essentiels au développement du système nerveux central. Chez la souris, ils jouent un rôle essentiel dans l’organisation de la moelle épinière et du télencéphale via la régulation de la signalisation Hedgehog/Gli. Cependant, malgré la perturbation fréquente de cette voie de signalisation dans les malformations du cerveau antérieur chez l'homme, le rôle des cils primaires dans la morphogenèse du cerveau antérieur a été peu étudié en dehors du télencéphale. Pendant mon doctorat, j’ai étudié le développement du diencéphale, de l’hypothalamus et des yeux chez des souris mut

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25

Oliveira, Aline Marcadenti de. "Associação entre indicadores de obesidade, polimorfismos dos genes FTO e MC4R e diabetes mellitus em pacientes com hipertensão arterial sistêmica." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/143524.

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26

Liu, Dong. "The role of Ftz-F1 in the regulation of chinook salmon gonadotropin II beta subunit gene." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0015/NQ46230.pdf.

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27

Suzuki, Taiga. "Segmentation gene product Fushi tarazu is an LXXLL motif-dependent coactivator for orphan receptor FTZ-F1." Kyoto University, 2002. http://hdl.handle.net/2433/150209.

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28

Lunardi, Cláudia Cruz. "Associação entre os polimorfismos dos genes candidatos FTO, TRHR e ACVR1b com a composição corporal e força muscular em idosas brasileiras." reponame:Repositório Institucional da UnB, 2013. http://repositorio.unb.br/handle/10482/13409.

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Tese (doutorado)—Universidade de Brasília, Faculdade de Ciências da Saúde, Programa de Pós-Graduação em Ciências da Saúde, 2013.<br>Submitted by Alaíde Gonçalves dos Santos (alaide@unb.br) on 2013-06-25T13:02:46Z No. of bitstreams: 1 2013_ClaudiaCruzLunardi.pdf: 2104527 bytes, checksum: 869f3995f555f48eaf76b6782428405f (MD5)<br>Approved for entry into archive by Guimaraes Jacqueline(jacqueline.guimaraes@bce.unb.br) on 2013-06-25T14:21:38Z (GMT) No. of bitstreams: 1 2013_ClaudiaCruzLunardi.pdf: 2104527 bytes, checksum: 869f3995f555f48eaf76b6782428405f (MD5)<br>Made available in DSpace on 2013-0

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29

Teixeira, Mayza Dalcin. "Estudo da associação de polimorfismos dos genes FTO, ABCA1, ABCA7 e ABCG1 com marcadores de obesidade e perfil lipídico em mulheres obesas." reponame:Repositório Institucional da UFPR, 2017. http://hdl.handle.net/1884/47563.

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Orientadora : Profª. Drª. Lupe Furtado-Alle<br>Coorientadora : Drª Luciane Viater Tureck<br>Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências Biológicas, Programa de Pós-Graduação em Genética. Defesa: Curitiba, 31/03/2017<br>Inclui referências : f. 85-88<br>Resumo: A maioria dos casos de obesidade e de dislipidemias possui origem complexa, pois é resultante da interação entre fatores genéticos e ambientais. Diversos genes têm sido relacionados com a susceptibilidade a estas doenças, incluindo variantes alélicas dos genes FTO, ABCA1, ABCA7 e ABCG1. Desse modo, o objetiv

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30

Gonçalves, Joana Fernandes. "Fsp27/CIDEC is a CREB target gene induced during fasting and regulated by fatty acid oxidation rate." Master's thesis, Faculdade de Ciências e Tecnologia, 2012. http://hdl.handle.net/10362/8198.

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Dissertação para obtenção do Grau de Mestre em Biotecnologia<br>Fsp27 (CIDEC the human homologue) is a lipid droplet protein that when overexpressed down regulates fatty acid oxidation (FAO). Previous results of this group showed that Fsp27/CIDEC expression is regulated by fasting in liver in a time-dependent manner. The present study aimed to elucidate the mechanism by which Fsp27/CIDEC is mediating fasting adaptation and regulated by FAO rate in liver. We showed that induction of Fsp27/CIDEC expression during fasting is not regulated by PPARα. Pharmacological inhibition of FAO by etomoxir

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31

Arbach, Jorge Mtanios Iskandar. "O fato gráfico: o humor gráfico como gênero jornalístico." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/27/27153/tde-22072009-182433/.

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Esta pesquisa busca referências que especifiquem o Humor Gráfico como uma das formas com que se constrói o discurso jornalístico. Desenvolve a questão a partir do uso da imagem pelo homem desde a pré-história, ao definir os sinais e elaborar suas significações O fio condutor do trabalho sustenta que a imagem é detentora de linguagem própria e que cada ser humano possui mecanismos inatos para assimilar seu discurso não-verbal. O trabalho trata em sua parte final da configuração da imagem no mundo contemporâneo como uma linguagem já inserida no meio informativo, porém não reconhecida.<br>This re

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Thomas, Matthew Robert. "Functional analysis of the ALS/FTD associated gene FUS using a novel in vitro genomic DNA expression system." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:176cbd1b-623e-41cb-9237-cd6c82fc0ad4.

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Aggregations of fused in sarcoma (FUS), a multifunctional RNA processing protein, define a pathological subtype of both frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), whilst mutations in the FUS gene are causative for ALS. To model the impact of FUS mutations, expression vectors containing the entire genomic sequence of FUS, up and downstream regions, and native promoter sequences have been generated. The constructs have been tagged with an mCherry fluorescent tag, and three separate pathological mutations (R244C, R521C, and P525L) have been separately inserted. Transge

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BORTOLI, SYLVIE. "Le recepteur de l'insuline : regulation de l'expression du gene dans les cellules fao et caracterisation du promoteur chez le rat." Paris 11, 1997. http://www.theses.fr/1997PA112311.

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Recemment, il a ete montre que l'hyperexpression du recepteur hepatique de l'insuline chez des rats atteints de diabete insulinopenique etait corrigee par l'administration d'insuline et de vanadate, un inhibiteur de phosphotyrosine phosphatases doue de proprietes insulinomimetiques. Afin de mieux comprendre les mecanismes d'action de ces agents, nous avons examine comparativement leurs effets sur differentes etapes de l'expression du gene du recepteur de l'insuline dans les cellules d'hepatome de rat fao. Nous avons mis en evidence une diminution de 2 fois du nombre cellulaire total de recepte

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Di, Nino Fiorant Küpfer Philippe Müller Serge. "Phénoplasticité -Polymorphisme génétique gestion conservatoire du genre Elodea /." Metz : Université Metz, 2008. ftp://ftp.scd.univ-metz.fr/pub/Theses/2008/Di_Nino.Fiorant.SMZ0836.pdf.

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Reproduction de : Thèse de doctorat : Science de la Vie : Ecologie : Metz : 2008. Reproduction de : Thèse de doctorat : Science de la Vie : Ecologie : Université de Neuchâtel (Suisse) : 2008.<br>Thèse soutenue en co-tutelle. Titre provenant de l'écran-titre. Notes bibliographiques. Index.

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Nascimento, Gabrielle Araújo do. "Avaliação do efeito de polimorfismos nos genes FTO, ABCA1, ABCA7 e ABCG1 sobre indicadores de obesidade e dislipidemias em crianças e adolescentes submetidos a treinamentos físico." reponame:Repositório Institucional da UFPR, 2017. http://hdl.handle.net/1884/47393.

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Orientadora : Profª Drª Luciane Viater Tureck<br>Coorientadora : Profª Drª Lupe Furtado Alle<br>Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências Biológicas, Programa de Pós-Graduação em Genética. Defesa: Curitiba, 27/03/2017<br>Inclui referências<br>Resumo: A obesidade e as dislipidemias geralmente estão associadas, e na maior parte dos casos possuem origem complexa, sendo decorrentes da interação entre os fatores ambientais e fatores genéticos. Dentre os fatores genéticos já conhecidos encontram-se genes relacionados ao metabolismo, como o gene FTO (Fat Mass and Obes

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Ommen, Ann Elizabeth. "Songs of the Ziegfeld Follies." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1179334149.

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KLEES, GERALDINE Dereu Mireille. "LES THEMES OBSESSIONNELS DANS L'OEUVRE ROMANESQUE DE JEAN GENET /." [S.l.] : [s.n.], 1992. ftp://ftp.scd.univ-metz.fr/pub/Theses/1992/Genet.Jean.LMZ921.pdf.

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Michita, Rafael Tomoya. "Apoptose na gestação : análise de variantes polimórficas dos genes FAS, FAS-L, BAX, BCL-2 e HLA-G na etiologia do abortamento de repetição." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/131963.

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O Abortamento de repetição (AR) é uma condição patológica definida pela ocorrência de duas ou mais perdas gestacionais consecutivas. Estima-se que esta desordem acometa 5% dos casais em idade reprodutiva. Esta condição clínica é classificada em dois subtipos clínicos: AR primário e AR secundário. Apesar dos esforços em investigar as causas desta desordem obstétrica, estima-se que em 50% dos casos a etiologia do AR permanece desconhecida. A reprodução humana implica em um paradoxo imunológico fundamental: no qual o feto representa uma entidade estranha ao sistema imune materno, sendo constituíd

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Santos, Renan Vasconcelos. "Influência dos carboidratos e da expressão de genes relacionados à parede celular na floculação de saccharomyces cerevisiae." Universidade Federal do Espírito Santo, 2013. http://repositorio.ufes.br/handle/10/5743.

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Made available in DSpace on 2016-12-23T13:49:02Z (GMT). No. of bitstreams: 1 Renan Vasconcelos Santos.pdf: 2145055 bytes, checksum: 12d61fee1beb0fbd0b1b459c9f469ff6 (MD5) Previous issue date: 2013-04-02<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>Since the dawn of civilization, man has used microbial fermentation to produce various consumer goods. The yeast Saccharomyces cerevisiae is undoubtedly the main factor in known fermentation processes, responsible for the production of bread, beer, wine, cachaça and bioethanol. S. cerevisiae was the first eukaryotic organis

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Pinke, Carolyne Assis Eigenheer [UNESP]. "Efeito da dieta hiperlipídica na programação fetal do metabolismo energético e atividade de enzimas digestivas em ratos." Universidade Estadual Paulista (UNESP), 2013. http://hdl.handle.net/11449/95222.

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Made available in DSpace on 2014-06-11T19:27:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-08-16Bitstream added on 2014-06-13T19:56:21Z : No. of bitstreams: 1 pinke_cae_me_botfmvz.pdf: 378341 bytes, checksum: 5a5e68e032c95138eddd986038c1d58b (MD5)<br>O objetivo deste estudo foi avaliar o efeito da restrição nutricional materna na gestação e/ou lactação sobre o desempenho e metabolismo de gordura e glicose em ratos machos adultos alimentados com dieta hiperlipídica (H) ou dieta padrão (C) pós-desmame (3-16 semanas). Ratos machos nascidos de mães alimentadas ad libitum (controle) o

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Araújo, Douglas do Carmo. "Este fato deixou o autorchocado e humilhado” : a construção da imagem do “ eu” na encenação discursiva das petições iniciais." Niterói, 2017. https://app.uff.br/riuff/handle/1/5117.

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Submitted by secretaria pós-letras repositorio (secretaria.repositorio@gmail.com) on 2017-09-25T20:57:13Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertação UFF - Integral - última versão.pdf: 2260097 bytes, checksum: 067d01a842f65d69fba5ead31ba181f4 (MD5)<br>Approved for entry into archive by Jussara Moore (jussaramoore@id.uff.br) on 2017-11-06T12:47:51Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertação UFF - Integral - última versão.pdf: 2260097 bytes, checksum: 067d01a842f65d69

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Semente, Rodrigo Soares. "Estudo e desenvolvimento de algoritmos criptogr?ficos para redes de sensores sem fio, utilizando t?cnicas de programa??o gen?tica." Universidade Federal do Rio Grande do Norte, 2015. http://repositorio.ufrn.br/handle/123456789/21141.

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Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-08-09T22:51:26Z No. of bitstreams: 1 RodrigoSoaresSemente_TESE.pdf: 2370466 bytes, checksum: 49b2c032e886eb4cc9db1b6d08d9b617 (MD5)<br>Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-08-11T00:12:44Z (GMT) No. of bitstreams: 1 RodrigoSoaresSemente_TESE.pdf: 2370466 bytes, checksum: 49b2c032e886eb4cc9db1b6d08d9b617 (MD5)<br>Made available in DSpace on 2016-08-11T00:12:44Z (GMT). No. of bitstreams: 1 RodrigoSoaresSemente_TESE.pdf: 2370466 bytes, checksum: 49b2c032e886eb4cc9db1b6d08

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Macal?s, Marta Ferreira. "Estudo de propriedades mec?nicas de tr?s resinas odontol?gicas comerciais fotopolimerizadas por LED e luz hal?gena." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2010. http://tede2.pucrs.br/tede2/handle/tede/3154.

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Made available in DSpace on 2015-04-14T13:58:36Z (GMT). No. of bitstreams: 1 423535.pdf: 597066 bytes, checksum: ce81a6cb6a7764590654a4d5a48d3e79 (MD5) Previous issue date: 2010-03-19<br>O presente estudo teve por objetivo estudar a influ?ncia do tempo e a intensidade de energia, de dois tipos de luz para fotopolimeriza??o, LED e luz hal?gena, na cura de tr?s resinas odontol?gicas compostas comerciais com diferentes fases org?nicas, Rok da fabricante SDI, fase org?nica UDMA; Filtek Z250, 3M ESPE, fase org?nica Bis-GMA, UDMA, Bis-EMA, TEGDMA; e Amelogem Plus da Ultradent, com fase org?nica Bi

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DERSON, DIDIER HENNEQUIN JACQUES. "La théâtralisation dans les romans du Marquis de sade." [S.l.] : [s.n.], 1998. ftp://ftp.scd.univ-metz.fr/pub/Theses/1998/Derson.Dider.LMZ9809_1.pdf.

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45

Harder, Jutta [Verfasser], da Costa Clarissa [Akademischer Betreuer] Prazeres, Bettina [Gutachter] Kuschel, and da Costa Clarissa [Gutachter] Prazeres. "Vitamin D receptor and its immunological role within the human placenta - Analysis of vitamin D metabolism and immunologically important genes at the feto-maternal interface / Jutta Harder ; Gutachter: Bettina Kuschel, Clarissa Prazeres da Costa ; Betreuer: Clarissa Prazeres da Costa." München : Universitätsbibliothek der TU München, 2019. http://d-nb.info/1203799446/34.

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46

Chazan, Lilian Krakowski. "Meio quilo de gente! - produção do prazer de ver e construção da pessoa fetal mediada pela ultra-sonografia: um estudo etnográfico em clínicas de imagem na cidade do Rio de Janeiro." Universidade do Estado do Rio de Janeiro, 2005. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=5902.

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O foco central desta tese consiste em procurar compreender um fenômeno que se verifica na atualidade em torno das imagens ultra-sonográficas fetais. O que era a princípio e em princípio uma tecnologia de imagem médica, inventada com propósitos diagnósticos, gradualmente transformou-se em objeto de consumo e lazer. Para investigar o fenômeno, a pesquisa teórica aborda como foram construídos o olhar e o observador modernos, e de que modo as tecnologias de imageamento médico incidem na construção social do corpo. Outro aspecto teórico consiste na investigação, de um ponto de vista sócio-histórico

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47

Cavalcante, Gustavo Ara?jo. "Otimiza??o de modelos de predi??o da perda de propaga??o aplic?veis em 3,5GHZ utilizando algoritmos gen?ticos." Universidade Federal do Rio Grande do Norte, 2010. http://repositorio.ufrn.br:8080/jspui/handle/123456789/15319.

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Made available in DSpace on 2014-12-17T14:55:43Z (GMT). No. of bitstreams: 1 GustavoAC__DISSERT.pdf: 2594771 bytes, checksum: b46a4c0b026ad559d9ed126acb92b471 (MD5) Previous issue date: 2010-07-09<br>Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior<br>The telecommunications industry has experienced recent changes, due to increasing quest for access to digital services for data, video and multimedia, especially using the mobile phone networks. Recently in Brazil, mobile operators are upgrading their networks to third generations systems (3G) providing to users broadband services su

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Danaher, Jessica. "Metabolic mechanisms of the fat mass and obesity-associated (FTO) gene." Thesis, 2016. https://vuir.vu.edu.au/34710/.

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The modern obesogenic lifestyle encompasses an environment that promotes weight gain in the form of body fat accumulation. Genetic variations can predispose some individuals to be more susceptible to developing obesity in a similar environment (Hainer et al. 2000; Maes et al. 1997; Mustelin et al. 2009). As the prevalence of obesity increases worldwide, and becomes a substantial socioeconomic issue, the need for research that deepens our understanding of the underlying genetic influences on complex regulatory mechanisms governing energy homeostasis becomes increasingly necessary. The fa

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49

Dietrich, Kerstin. "Molekulare Evolution der metabolisch relevanten Gene MTNR1B (Melatoninrezeptor 1B) und FTO (Fat Mass and Obesity Associated)." Doctoral thesis, 2011. https://ul.qucosa.de/id/qucosa%3A11832.

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Die hier vorliegende Arbeit zeigt die molekulare Evolution des Melatoninrezeptor 1 B-Gens (MTNR1B) und des Fat Mass and Obesity Associated-Gens (FTO). Für beide Gene wurden in genomweiten Assoziationsstudien (GWAS) Varianten entdeckt, welche zu der Entwicklung einer Adipositas bzw. deren Folgeerkrankungen beitragen können. So wurde für Einzelbasenaustausche (SNPs) im MTNR1B (rs10830963, rs4753426) eine Verschlechterung der Nüchternglukose sowie der Insulinausschüttung gezeigt. Zudem wurde für die Allelfrequenz des rs4753426 C-Allels ein Zusammenhang mit der täglichen Sonnenscheindauer beschrie

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Hopkins, Racquel L. "Quantitatively Assessing the Genetics of Hair Color in Addition to Identifying Regulatory Elements Impacting Body-Mass Index in the FTO Gene." Thesis, 2020. http://hdl.handle.net/1805/23345.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Obesity is a medical condition whose rates have seen a rise in both the United States and worldwide in recent decades. Numerous studies have been done to understand obesity, and through the use of GWAS researchers have been able to find multiple genetic factors that can contribute to obesity in mammals. One proposed cause of obesity are genetic impacts on cilia formation in the CNS, which causes downstream effects on food intake and energy expenditure, causing obesity via overeating and decreased activity. In the first half of thi

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