Academic literature on the topic '004.4:519.816 (043.3)'

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Journal articles on the topic "004.4:519.816 (043.3)"

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Marincowitz, Carl, Omar Bouamra, Tim Coates, et al. "1427 The effect of the COVID-19 pandemic on major trauma presentations and patient outcomes in English hospitals." Emergency Medicine Journal 39, no. 12 (2022): A960.2—A964. http://dx.doi.org/10.1136/emermed-2022-rcem2.2.

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Aims, Objectives and BackgroundThere is evidence that COVID-19 ‘lockdowns’ may have contributed to increased non-accidental injury, domestic violence and self-harm related to deteriorating mental health. Internationally, there is also evidence that the diversion of health care resources may led to worse outcomes for patients presenting with major trauma. There has been no previous national evaluation of ‘lockdown’ measures impact on the characteristics, treatment pathways and outcomes of trauma patients in EnglandWe aimed to assess the impact of successive lockdowns on the volume, demographics
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N., Kamel, Mouheb Y., Kamariz S., Aouchiche F., Moudir D., and Arabi A. "Synthesis and characterization of a Mo-rich aluminoborosilicate glass by a double melt process." European Journal of Advances in Engineering and Technology 6, no. 2 (2019): 17–25. https://doi.org/10.5281/zenodo.10686913.

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<strong>ABSTRACT</strong> A Mo-rich aluminoborosilicate glass dedicated for nuclear waste confinement, containing 0.3 to 0.6 wt.% of Cs, is synthesized by a double melting at 1380&deg;C during 3 h, followed by a 2 h annealing step at 600&deg;C. The glasses density varied randomly with the Cs content from 1.43 to 2.73. The X-ray diffraction phase identification reveals similar features for the glasses with 0.3 and 0.6wt.%, with a minor crystalline phase identified as powellite. For 0.4 wt.% Cs, traces of crystalline phases of monoclinic coesite SiO<sub>2</sub>, iron silicate (Fe<sub>3</sub>Al<s
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Doshi, Chirag, Mazyar Zahir, Anosh Dadabhoy, et al. "Impact of insurance type on outcomes after radical cystectomy for bladder cancer." Journal of Clinical Oncology 43, no. 5_suppl (2025): 679. https://doi.org/10.1200/jco.2025.43.5_suppl.679.

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679 Background: A patient’s insurance status can significantly impact their access to care, potentially altering their treatment course and outcomes. This study aimed to evaluate the potential influence of different insurance statuses on oncological outcomes, including survival. Methods: We utilized our prospectively maintained IRB-approved radical cystectomy (RC) database (#HS-01B014) to identify all muscle invasive bladder cancer (MIBC) patients who underwent neoadjuvant chemotherapy (NAC) followed by RC from 2000 to 2023. Patients were then categorized based on primary insurance type to Pre
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Dörner, T., Y. Tanaka, M. Mosca, et al. "POS0714 POOLED SAFETY ANALYSIS OF BARICITINIB IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: RESULTS FROM THREE RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED, CLINICAL TRIALS." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 639.1–639. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2375.

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BackgroundBaricitinib (BARI), an oral selective inhibitor of Janus kinase 1 and 2 approved for the treatment of rheumatoid arthritis and atopic dermatitis, has been evaluated in clinical studies in patients with systemic lupus erythematosus (SLE).ObjectivesTo assess the safety profile of BARI in patients with SLE.MethodsPatients with SLE receiving stable background therapy were randomised 1:1:1 to BARI 2-mg, 4-mg, or placebo (PBO) once daily in one 24-week, phase 2 (NCT02708095) and two 52-week, phase 3, PBO controlled studies (NCT03616912 and NCT03616964).ResultsA total of 1,849 patients were
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Khare, Reeti, Tarush Kothari, Joseph Castagnaro, Bryan Hemmings, May Tso, and Stefan Juretschko. "Active Monitoring and Feedback to Improve Blood Culture Fill Volumes and Positivity Across a Large Integrated Health System." Clinical Infectious Diseases 70, no. 2 (2019): 262–68. http://dx.doi.org/10.1093/cid/ciz198.

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AbstractBackgroundThe sensitivity of blood cultures increases with the volume of blood collected. However, hospitals face challenges in collecting adequate volume, and underfilled blood bottles are ubiquitous.MethodsBlood bottle fill volumes were measured using an automated monitoring system across multiples sites (10 hospitals, 3 laboratories) within a large suburban/urban health system. Baseline fill volumes were measured for 4 months. A quality improvement program was then implemented over 36 months. Strategies to improve fill volumes included education, standardized data collection, novel
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Cairo, Mitchell S., Erin Cooney, Mark Krailo, et al. "A Phase I Study of 90Y-Ibritumomab-Tiuxetan (90Y-It) in Children with Recurrent/Refractory CD20 Positive Lymphoma: A Cog Phase I Consortium Study." Blood 106, no. 11 (2005): 2448. http://dx.doi.org/10.1182/blood.v106.11.2448.2448.

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Abstract More than 98% of newly diagnosed childhood B-NHL expresses CD20 (Perkins/Cairo, Clin Adv Hem/Onc 2003). The prognosis for children and adolescents with recurrent CD20 positive NHL, particularly DLBCL and BL, is dismal (Cairo et al, Am J Hem, 2003, Cairo et al, Br J Hem, 2003). A radiolabeled anti-CD20 antibody, 90Y-IT, has recently received FDA approval for adults with recurrent indolent CD20+ B-NHL. The dose limiting toxicity in adults has been myelosuppression (Witzig et al, JCO, 2003). Through the COG Phase I Consortium, we evaluated the safety of 90Y-IT in Pts with refractory chil
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De Agustin, J. J., G. Añez, D. Reina-Sanz, et al. "AB1116 APREMILAST IN PSORIATIC ARTHRITIS. ULTRASOUND ANALYSIS (JOINT-ENTHESES-UNGUEAL INDEX) OF THE EFFICACY AND VARIABLES CORRELATION STUDY." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1787–88. http://dx.doi.org/10.1136/annrheumdis-2023-eular.1397.

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BackgroundWe conducted a study using ultrasonography (US) to evidence inflammatory changes (joint-enthesis-ungueal) in active PsA (aPsA) patients who started Apremilast (A) in clinical practice.ObjectivesObtain a 20, 50, 70 % reduction in the US index (UIC) at 12 months, and study correlation between variables.MethodsPhase IV, multicenter, prospective and open-label clinical trialconductedin 9 centresfrom 2018 to 2021. All patients signed the informed consent. Approval by the ethical committee was obtained, code PSA-PI-006421. PsA patients (≥ 2 swollen joints), ≥ 2 joint US synovitis and ≥ 1 U
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Taparra, Kekoa, Vera Qu, and Erqi Pollom. "Disparities in Survival and Comorbidity Burden Between Asian and Native Hawaiian and Other Pacific Islander Patients With Cancer." JAMA Network Open 5, no. 8 (2022): e2226327. http://dx.doi.org/10.1001/jamanetworkopen.2022.26327.

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ImportanceImproper aggregation of Native Hawaiian and other Pacific Islander individuals with Asian individuals can mask Native Hawaiian and other Pacific Islander patient outcomes. A comprehensive assessment of cancer disparities comparing Asian with Native Hawaiian and other Pacific Islander populations is lacking.ObjectiveTo compare comorbidity burden and survival among East Asian, Native Hawaiian and other Pacific Islander, South Asian, and Southeast Asian individuals with non-Hispanic White individuals with cancer.Design, Setting, and ParticipantsThis retrospective cohort study used a nat
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Steinkamp, Gratiana, Hans Demmelmair, Ina Rühl‐Bagheri, Horst von der Hardt, and Berthold Koletzko. "Energy Supplements Rich in Linoleic Acid Improve Body Weight and Essential Fatty Acid Status of Cystic Fibrosis Patients." Journal of Pediatric Gastroenterology and Nutrition 31, no. 4 (2000): 418–23. http://dx.doi.org/10.1002/j.1536-4801.2000.tb07150.x.

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ABSTRACTBackgroundPatients with cystic fibrosis who have steatorrhea frequently are underweight and have essential fatty acid (EFA) depletion, which is associated with a poor clinical course. It has been stated that poor EFA status is difficult to correct in patients with cystic fibrosis, and an impaired EFA metabolism with reduced synthesis of long‐chain polyunsaturated fatty acids has been proposed. In this study, the effects of an oral energy supplement rich in linoleic acid were investigated in patients with cystic fibrosis who had a body weight below 95% of normal for height.MethodsThirty
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Sakhin, V., M. Grigoriev, O. Rukavitsyn, E. Kryukov, and S. Kazakov. "SAT0089 FEATURES OF THE SECRETION OF INTERLEUKIN-6, INTERLEUKIN-10, TUMOR NECROSIS FACTOR ALPHA IN PATIENTS WITH RHEUMATOID ARTHRITIS ASSOCIATED WITH ANEMIA." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 978.1–979. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1264.

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Background:Anemia is widespread in rheumatic patients and is an important extra-articular manifestation that correlates with physical disability and increased mortality. The pathogenesis of such anemia is complex and multifactorial, including due to the influence of pro-inflammatory cytokines.Objectives:Our aim was to study the characteristics of the secretion of interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor-alpha (TNF-α) in patients with rheumatoid arthritis (RA) with anemia of chronic diseases (ACD), iron deficiency anemia (IDA) and a combination of ACD / IDA, as well a
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