Relevant bibliographies by topics / -024.538 (043.5)

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Academic literature on the topic '-024.538 (043.5)'

Author: Grafiati
Published: 30 May 2022
Last updated: 31 July 2025

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Journal articles on the topic "-024.538 (043.5)"

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Lokhandwala, S., T. Allard, T. Riggins, and R. M. Spencer. "0334 Hippocampal Development, Slow Wave Activity, and Nap-Dependent Memory Consolidation in Early Childhood." Sleep 43, Supplement_1 (2020): A127. http://dx.doi.org/10.1093/sleep/zsaa056.331.

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Abstract Introduction Naps support memory consolidation in early childhood. In adults, nap-dependent declarative consolidation is associated with SWA. SWA increases from early childhood into adulthood, and the shift of SWA from occipital to frontal distribution (F/O-ratio) is a marker of brain maturation. Thus, we explored how electrophysiological and structural characteristics of brain development relate to nap-dependent declarative learning in early childhood. Methods Twelve preschool-age children (8 female, M=48 months, SD=0.44) have completed three sessions (~1wk apart) within a larger stu
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Gore, C., D. Hill, and S. Lee. "C-57 Prematurity and Perinatal Insult: Examining the relationships between parent and teacher ratings of executive functioning and academic readiness." Archives of Clinical Neuropsychology 34, no. 6 (2019): 1086. http://dx.doi.org/10.1093/arclin/acz034.219.

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Abstract Objective Extremely preterm children and those with a history of perinatal insult (e.g., hemorrhage, hypoxic-ischemic injury) show higher rates of cognitive and academic problems, including executive functioning (EF). EF becomes increasingly important in elementary school as curriculum demands increase. The current study examines the relationship between parent- and teacher-reported EF and early academic performance in this population at school-age. Method This study reviewed retrospective neuropsychological evaluations in a sample of 135 patients (ages 3:9-10:5 years, M = 5.8) from a
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Wu, Lin, Liming Cao, Likun Chen, et al. "Molecular characterization of NSCLC-like and SCLC-like subsets in Chinese pulmonary large cell neuroendocrine carcinoma (LCNEC)." Journal of Clinical Oncology 37, no. 15_suppl (2019): e13125-e13125. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e13125.

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e13125 Background: LCNEC is an aggressive, biologically heterogenous carcinoma which can be molecularly characterized as SCLC-like and NSCLC-like. Accurate distinction of molecular subset is of major clinical relevance since it may guide treatment choices in LCNEC. Here we determined the genomic characteristics of the two LCNEC subsets in a Chinese cohort to clarify their correlations with traditional lung cancer histologies. Methods: FFPE samples from 31 LCNECs were sequenced using a 520-cancer-related gene panel, with an average sequencing depth of 1353X. Comparative mutational analysis was
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Moerbeck, Leonardo, Ricardo Parreira, Gonçalo Seixas, Rita Velez, Ana Domingos, and Sandra Antunes. "Update on tick-borne rickettsioses in mainland Portugal: emerging threats and potential vectors." Parasites & Vectors 17, no. 1 (2024): 1–11. https://doi.org/10.1186/s13071-024-06627-5.

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Moerbeck, Leonardo, Parreira, Ricardo, Seixas, Gonçalo, Velez, Rita, Domingos, Ana, Antunes, Sandra (2024): Update on tick-borne rickettsioses in mainland Portugal: emerging threats and potential vectors. Parasites & Vectors (538) 17 (1): 1-11, DOI: 10.1186/s13071-024-06627-5, URL: https://doi.org/10.1186/s13071-024-06627-5
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Hosokawa, Kohei, Jong Wook Lee, Jun Ho Jang, et al. "Long-Term Follow-up of Patients with Aplastic Anemia Enrolled in Phase 2/3 Trials of Immunosuppressive Therapy Plus Romiplostim As a First-Line Treatment: Two-Year Interim Analysis." Blood 144, Supplement 1 (2024): 1310. https://doi.org/10.1182/blood-2024-193925.

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Background Phase 2/3 clinical trials evaluating the safety and efficacy of immunosuppressive therapy (IST) plus romiplostim in IST-naïve patients with aplastic anemia (AA) have been previously reported (531-003 trial [rabbit ATG+CsA+romiplostim; NCT03957694] and 531-004 trial [CsA＋romiplostim; NCT04095936]). The long-term data on efficacy outcomes and safety profiles are lacking after completion of 27 or 53 weeks romiplostim treatment. As the collection of data on long-term treatment outcomes and disease monitoring is essential owing to the chronic life-threatening nature of the disease, we co
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Metzger, R., C. G. Leichman, K. D. Danenberg, et al. "ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy." Journal of Clinical Oncology 16, no. 1 (1998): 309–16. http://dx.doi.org/10.1200/jco.1998.16.1.309.

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PURPOSE We have previously shown that relative thymidylate synthase (TS) mRNA levels in primary gastric adenocarcinomas treated with fluorouracil (5-FU) and cisplatin are inversely associated with response and survival. This is a presumed function of TS as a target for 5-FU activity. We now test the hypotheses that the relative mRNA level of the excision repair cross-complementing (ERCC1) gene is inversely associated with response and survival as an independent function of cisplatin efficacy. PATIENTS AND METHODS Patients had intact, untreated, primary gastric adenocarcinoma cancer and were ev
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Shin, S., H. Jeung, J. Ahn, et al. "Mobilized circulating endothelial progenitor cells after the first cycle of chemotherapy with prophylactic G-CSF can be used as a predictive biomarker and patient selection marker for anti-angiogenesis combination treatment." Journal of Clinical Oncology 25, no. 18_suppl (2007): 4638. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.4638.

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4638 Background: We investigated whether the level of circulating endothelial progenitor cells (CEPs) and endothelial cells (CECs) could be used as surrogate predictors of clinical outcome in patients receiving taxotere-based chemotherapy for advanced gastric cancer. Methods: Peripheral blood mononuclear cells were obtained in 49 gastric cancer patients who received taxotere combined with 5-FU and leucovorine (FLT regimen) after chemotherapy and prophylactic G-CSF treatment. To categorize the endothelial cells, immunofluorescent staining for specific endothelial cell markers (CD34, vWF, P1H12,
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Davis, L. E., A. R. Hohimer, G. D. Giraud, M. S. Paul, and M. J. Morton. "Vascular pressure-volume relationships in pregnant and estrogen-treated guinea pigs." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 257, no. 5 (1989): R1205—R1211. http://dx.doi.org/10.1152/ajpregu.1989.257.5.r1205.

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We investigated the relationship between mean circulatory filling pressure (MCFP) and blood volume in nonpregnant (NP), estrogen-treated (E), and pregnant (P) guinea pigs. Reversible circulatory arrest was produced by rapid ventricular pacing or acetylcholine in unanesthetized animals remote from surgery. MCFP (mmHg) was higher for E (7.1 +/- 0.3) than for NP (5.8 +/- 0.5) or P (5.3 +/- 0.4). The gradient for venous return, the difference between MCFP and right atrial pressure (mmHg), did not differ in NP- (6.0 +/- 0.5), P- (5.8 +/- 0.5), or E- (5.8 +/- 0.4) treated animals. Capacitance, the b
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Chung, Dong Seok, C. W. Jea, Jae Hong Yoon, and J. K. Kim. "Effect of Mn Addition on the Mechanical Properties in Al-Cu-Li-Mg-Ag-Zr Alloys." Materials Science Forum 539-543 (March 2007): 481–86. http://dx.doi.org/10.4028/www.scientific.net/msf.539-543.481.

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The mechanical properties of Al–5%Cu–1.3%Li–0.4%Mg–0.4%Ag–1.16%Zr alloys without Mn and with 0.3%, 0.6% and 1.2% Mn have been investigated after the aging at the temperatures of 90, 150, 180, and 230 oC. With Mn addition the alloys show a good work-hardening property, and the elongation of alloys increases. With the 0.6% Mn the best elongation can be obtained. The strength of alloys with 0.3% or 1.2% Mn is lower than that of the alloy without Mn, whereas the strength of alloy with 0.6% Mn is almost same as that of the alloy without Mn. In the alloy with 0.6% Mn aged at 180 oC for 12 hours the
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Puchulu, Félix. "Por el no." Revista de la Sociedad Argentina de Diabetes 56, no. 3Sup (2022): 40. http://dx.doi.org/10.47196/diab.v56i3sup.532.

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El agregado de metformina en pacientes adultos con diabetes mellitus tipo 1 (DM1) favoreció pequeños descensos de peso y de los niveles lipídicos, pero no ha mejorado la HbA1c.
 Los estudios de ARGLP-1 en DM1 se desarrollaron con liraglutida y demostraron modestas reducciones de la HbA1c (0,3-0,4%), descenso de peso (5 kg) y reducción de la dosis de insulina (10-12%). Como efectos adversos, también se observó mayor presentación de náuseas y vómitos, con el riesgo que supone en un paciente insulinotratado. La tasa de hipoglucemia sintomática aumentó con liraglutida 1,8 mg y 1,2 mg vs place
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Books on the topic "-024.538 (043.5)"

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Zaletaev, Dmitriy, Nadezhda Shilova, Viktoriya Musatova, Marina Min'zhenkova, Zhanna Markova, and Sergey Kucev. Molecular (cytogenetic diagnosis of Prader-Willi syndrome). Triumph Publishing, 2023. http://dx.doi.org/10.29039/978-5-94472-131-0-58-03-2023.

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This teaching aid is devoted to the theoretical and practical aspects of the genetic diagnosis of Prader-Willi syndrome and is compiled in accordance with the Federal State Educational Standard of Higher Education in the specialties 08/31/30 "genetics", 05/31/02 "pediatrics", 08/31/06 "laboratory genetics", 08/31/53 "endocrinology", 08.31.42 "neurology", 08.31.05 "clinical laboratory diagnostics" and the work programs of the Department of Medical Genetics of the IViDPO FGBNU "MGNTS", as well as taking into account the professional standards of doctors of the above specialties; scientific speci
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Book chapters on the topic "-024.538 (043.5)"

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Chernogor, Leonid, and Yiyang Luo. "Statistical Analysis of Seismic and Tsunami Waves Generated by the 2022 Tonga Volcano’s Eruption." In A Comprehensive Study of Volcanic Phenomena [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1006881.

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On January 15, 2022, a catastrophic explosive eruption occurred at the Hunga-Tonga-Hunga-Ha’apai (HTHH) volcano in the Kingdom of Tonga, marking a significant geological event. The eruption, located at 20°54′S, 175°38′W, involved 3–5 powerful explosions, with the most severe at 04:15 UTC, and was accompanied by an earthquake of magnitude Ms ≈ 5.8. The eruption’s source energy was estimated between 6.5 to 23 TJ and 19 to 69 TJ, while the energy of the associated air waves ranged from 16.7 to 75.3 TJ and 2 ± 0.8 PJ. Classified as a supervolcano, the total energy release was approximately 17.6 ±
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Feather, Leonard, and Ira Gitler. "l." In The Biographical Encyclopedia of Jazz. Oxford University PressNew York, NY, 1999. http://dx.doi.org/10.1093/oso/9780195074185.003.0012.

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Abstract La porta, john d., cl., saxes, comp, arr; b. Philadelphia, PA, 4/1/20; d. Sarasota, FL, 5/12/04. Began on cl. at age 9. Stud. cl. w. Wm. Dietrich, Joseph Gigliotti, Leon Russianoff 1932–57. Pl. in Youth Symph. cond. by Leopold Stokowski ’37–8. Stud. comp. w. Ernst Toch, Alexis Haieff ’45–6; improv. w. Lennie Tristano ’47–8; received B. Mus. ’56, M. Mus. Ed. ’57 fr. Manh. Sch. of Mus. Pl. w. Bob Chester, Richard Himber, Ray McKinley early ’40s; Woody Herman ’44–6; Tristano late ’40s; Charles Mingus ’50–67; Metronome All-Stars ’51–2; own gps ’51–62. Founding member and mus. dir. of Jazz
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Demirtaş, Mehmet Can. "14 Mayıs 2023 Cumhurbaşkanı Seçimi’nde Adayların Twitter (X) Platformu Kullanımlarına Yönelik Karşılaştırmalı Bir Değerlendirme." In Sosyal Bilimlerde Akademik Araştırma ve Değerlendirmeler - I. Özgür Yayınları, 2023. http://dx.doi.org/10.58830/ozgur.pub308.c1405.

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Temsili demokrasinin fonksiyonlarının tam olarak sağlanması sürecinde bireylerin yönetim haklarını kendi öz iradeleri ile temsilcilerine devretmelerine olanak tanıyan seçimler, yönetim gücünü elde etmek isteyen siyasi parti ve adaylar açısından önemli bir rekabet alanını ortaya çıkarmaktadır. Siyasal rekabette başarı ise daha yüksek sayıda seçmen tercihinin elde edilmesine bağlı olduğundan siyasi parti ve adaylar seçmen tercihlerini etkileme sürecinde pazarlama çabalarına başvurmaktadır. Günümüzde ilgili pazarlama süreçlerinin teknolojik gelişmeler doğrultusunda dijital ortamlara yönelmesi, ye
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Amardeilh Florence, Bousquet Cédric, Guillemin-Lanne Sylvie, et al. "A Knowledge Management Platform for Documentation of Case Reports in Pharmacovigilance." In Studies in Health Technology and Informatics. IOS Press, 2009. https://doi.org/10.3233/978-1-60750-044-5-517.

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Most countries have developed information systems to report drug adverse effects. However, as in other domains where systematic reviews are needed, there is little guidance on how systematic documentation of drug adverse effects should be performed. The objective of the VigiTermes project is to develop a platform to improve documentation of pharmacovigilance case reports for the pharmaceutical industry and regulatory authorities. In order to improve systematic reviews of adverse drug reactions, we developed a prototype that first reproduces and standardizes search strategies, then extracts inf
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Khajouei Reza, de Jongh Dennis, and Jaspers Monique W.M. "Usability Evaluation of a Computerized Physician Order Entry for Medication Ordering." In Studies in Health Technology and Informatics. IOS Press, 2009. https://doi.org/10.3233/978-1-60750-044-5-532.

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Despite CPOE (Computerized Physician Order Entry) systems' potential to enhance patient safety by reducing medication errors, recent studies have cast some doubts on their role in error reduction. CPOE systems with poorly designed interfaces have proven to cause users dissatisfaction and to introduce new kind of errors in the ordering process, suggesting a threat instead of an enhancement of patient safety. The main objective of this study is to identify usability problems related to a CPOE medication system's design and determining their severities. Two experts completed a cognitive walkthrou
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Ceusters Werner, Capolupo Maria, Smith Barry, and De Moor Georges. "An Evolutionary Approach to the Representation of Adverse Events." In Studies in Health Technology and Informatics. IOS Press, 2009. https://doi.org/10.3233/978-1-60750-044-5-537.

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One way to detect, monitor and prevent adverse events with the help of Information Technology is by using ontologies capable of representing three levels of reality: what is the case, what is believed about reality, and what is represented. We report on how Basic Formal Ontology and Referent Tracking exhibit this capability and how they are used to develop an adverse event ontology and related data annotation scheme for the European ReMINE project.
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"TABLE8TocolDerivativeContentinCerealGrainsTocolderivatives ( m g / 100g ) aGrainsa -T a -T -3 1 3 -T I 3 -T -3 y -T y -T -3 6 -T 6 -T -3 TotalRef . Barley0 . 2 -0 . 4 1 . 1 -1 . 3 0 . 0 4 -0 . 4 0 . 3 -0 . 7 0 . 0 3 -0 . 5 0 . 2 0 . 0 1 -0 . 040 . 1 6 < 5 . 030 . 4 1 . 3 0 . 3 0 . 7 0 . 050 . 2 0 . 1 -8 9 0 . 5 1 . 3 0 . 020 . 7 0 . 070 . 8 0 . 020 . 0750 . 3 1 . 6 < 0 . 1 0 . 6 0 . 1 0 . 6 < 0 . 1 -9 0Genotype0 . 7 2 -1 . 162 . 3 8 -4 . 300 . 0 5 -0 . 130 . 3 1 -1 . 210 . 0 4 -0 . 120 . 2 4 -0 . 960 . 0 4 -0 . 140 . 0 2 -0 . 204 . 2 2 -8 . 0091Location0 . 8 8 -1 . 113 . 0 5 -3 . 630 . 002 -0 . 190 . 6 7 -0 . 750 . 070 . 5 0 -0 . 560 . 0 4 -0 . 130 . 0 7 -0 . 115 . 6 7 -6 . 0891Malt1 . 003 . 070 . 140 . 460 . 040 . 390 . 040 . 065 . 292Spentgrain2 . 029 . 210 . 311 . 600 . 091 . 760 . 120 . 1815 . 392Corn0 . 6 -2 . 1 0 . 2 -0 . 5 -0 . 5 -1 . 1 3 -0 . 6 0 . 2 0 . 4 3 . 8 0 . 5tr890 . 1 -2 . 3 0 . 3 -0 . 7 1 . 1 -7 . 1 0 . 1 -1 . 9 2 . 6 -1 0 . 29Millet0 . 05tr1 . 3 0 . 489 -0 . 1 < 0 . 1 0 . 1 1 . 7 < 0 . 1 0 . 690Bulrushmillet0 . 1 3 -5 . 540 . 530 . 080 . 25Foxtailmillet0 . 190 . 040 . 042 . 780 . 065Fingermillet0 . 320 . 050 . 031 . 7 6 -5 Pearlmillet0 . 041 . 5 -0 . 355 -O ats0 . 3 -1 . 7 0 . 7 -1 . 1 0 . 1 -0 . 2 0 . 1 -0 . 3 0 . 3 -3 0 . 7 0 . 7 0 . 2 0 . 1 0 . 3 -8 9 1 . 3 -4 . 0 0 . 2 -6 . 3 0 . 3 -0 . 5 0 . 3 -1 . 1 0 . 7 -6 . 1 0 . 910 . 140 . 321 . 3 -3 . 011Genotype0 . 5 5 -0 . 960 . 9 1 -1 . 860 . 0 7 -0 . 130 . 0 5 -0 . 150 . 0 5 -0 . 130 . 0 0 -0 . 061 . 9 -3 . 091Location0 . 7 2 -0 . 961 . 1 7 -1 . 830 . 0 7 -0 . 110 . 0 5 -0 . 140 . 0 8 -0 . 110 . 0 1 -0 . 032 . 1 -3 . 191RiceBrownrice0 . 6 0 . 4 0 . 1 < 0 . 010 . 1 0 . 7 < 0 . 190Polishedrice < 0 . 1 0 . 1 < 0 . 1 < 0 . 1 < 0 . 1 0 . 3 < 0 . 190Milledrice0 . 0 5 -0 . 3 0 . 2 -0 . 5 0 . 1 -0 . 3 -< 0 . 0440 . 3tr0 . 3 0 . 5 0 . 04890 . 060 . 080 . 260 . 020 . 025 -R ye0 . 5 -1 . 8 0 . 7 -1 . 5 0 . 3 -0 . 7 0 . 8 -0 . 9 0 . 6 -3 0 . 8 1 . 3 0 . 4 0 . 9 0 . 689Flour0 . 6 0 . 4 0 . 3 0 . 6 -9 0Meal1 . 0 1 . 4 0 . 3 1 . 190Sorghum0 . 081 . 155Triticale0 . 911 . 030 . 301 . 515Winter0 . 7 -0 . 9593Spring1 . 3 5 -1 . 4593 -W heat1 . 0 0 . 2 0 . 4 1 . 9 -5 0 . 9 -1 . 8 0 . 3 -0 . 7 2 . 5 -3 . 6 4 . 9 -5 . 831 . 0 0 . 4 0 . 9 2 . 5 0 . 0889aTocopherolsincludea -T , 0 -T , y -T , and5 -T , andtocotrienolsincludea -T -3 , 0 -T -3 , y -T -3 , andS -T -3 . ( -) denotedatanotreported ." In Handbook of Cereal Science and Technology, Revised and Expanded. CRC Press, 2000. http://dx.doi.org/10.1201/9781420027228-47.

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Conference papers on the topic "-024.538 (043.5)"

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Nordin, Andrew D., Joshua P. Bailey, and Janet S. Dufek. "Implications of Increased Lower Extremity Movement Variability on Fall Susceptibility at Increased Stride Lengths During Locomotion." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-63804.

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The purpose of this examination was to explore the effects of stride length (SL) perturbations on walking gait, relative to preferred walking (PW) and running (PR), via lower extremity range of motion (ROM) variability. ROM variability at the hip, knee, and ankle joints, in the sagittal and frontal planes were used in evaluating motor control of gait, where increased gait variability has been previously implicated in fall susceptibly. Nine participants (5 male, 4 female; mean age 23.11±3.55 years, height 1.72±0.18m, mass 72.66±14.37kg) free from previous lower extremity injury were examined. K
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Kim, In-Tae, Hwan-Seo Park, Yong-Zun Cho, Kwang-Wook Kim, Seong-Won Park, and Eung-Ho Kim. "Characteristics of Solidified Products Containing Radioactive Molten Salt Waste." In The 11th International Conference on Environmental Remediation and Radioactive Waste Management. ASMEDC, 2007. http://dx.doi.org/10.1115/icem2007-7303.

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For a treatment of molten salt wastes generated from a pyroprocessing of oxide spent fuel, we had suggested a stable chemical route, named GRSS (Gel-Route Stabilization &amp; Solidification), and a subsequent consolidation method. By using this method, a series of monolithic wasteforms with different conditions were fabricated, and then their physicochemical properties were investigated. A simulated salt containing 90wt% LiCl, 6.8wt% CsCl, and 3.2wt% SrCl2 was treated with a gel-forming material system, Si/Al/P = 0.4/0.4/0.2 and 0.35/0.35/0.3, and the gel-products were treated at 1100C° after
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Reisner, H. M., E. A. Reisner, D. D. Kostyu, B. C. Lubahn, C. McMillan, and G. C. White. "POSSIBLE ASSOCIATION OF HLA AND Gm WITH THE ALLOIMMUNE RESPONSE TO FVIII." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644021.

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Between 5 and 15% of individuals with severe hemophilia A are at risk of developing inhibitors (alloantibodies) to FVIII. Genetic factors are important in determining risk, but the nature of these factors is poorly defined. The human immune response to a wide variety of antigens has been associated with the HLA and/or Gm loci. Hence, we have investigated polymorphisms at these two loci in hemophilia A patients with and without inhibitors.DATA SET: To date 127 hemophiliacs have been Gm or HLA typed. Forty-eight are inhibitor positive (I+) based on positive FVIII neutralization assays. This repr
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Yang, Siheng, Tao Xu, Quanhong Xu, and Yuzhen Lin. "Influence of Water Addition Upstream Diffuser Inlet on Lean Blowout and Emissions in the TeLESS-II Combustor." In ASME Turbo Expo 2020: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/gt2020-14549.

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Abstract Water is likely to be ingested into aeroengines under conditions of rainfall or hail, increasing the risk of flame blowout and posing great influence on the combustion characteristics. The chemical and thermal effects of inlet water addition on lean blowout and emissions in the TeLESS-II centrally staged LPP (Lean Premixed Prevaporized) combustor are investigated in this paper. Experiments are carried out at various conditions relevant to gas turbine combustors: the inlet temperature range is 450 K – 533 K, the inlet pressure range is 0.3 Mpa – 0.4 Mpa. The range of water mass fractio
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Victoria, Isabel Cristina Moreira, Attilio Bolivar Ourives de Figueiredo, Eliete Auxiliadora Assunção Ourives, Luiz Fernando Gonçalves de Figueiredo, Giovana De Freitas Rabelo Ribeiro, and Francisco Gómez Castro. "A COMPREENSÃO SISTÊMICA E O PENSAMENTO DO DESIGN PARA O DESENVOLVIMENTO DE PRODUTOS PARA A CULTURA SLOW FOOD E DE PRATICAS COLABORATIVAS." In Systems & Design 2017. Universitat Politècnica València, 2017. http://dx.doi.org/10.4995/sd2017.2017.6645.

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RESUMO A sociedade atual vive em um contexto tumultuoso, sendo comum as pessoas viverem de forma mais estressadas, se alimentando mal e convivendo cada vez menos com as pessoas, perdendo oportunidades de fazer e manter relacionamentos pessoais. Como este estilo de vida está saturado, gerando problemas de saúde aos indivíduos, existem diversos estudos que comprovam a tendência de que as pessoas buscarão um melhor aproveitamento do seu tempo, com um maior contato com a natureza, dando valor ao seu próprio bem-estar, prestando mais atenção no que consome e em como consome, assim como a valorizaçã
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