Relevant bibliographies by topics / 1-Azaspirocycles

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  1. Journal articles
  2. Dissertations / Theses

Academic literature on the topic '1-Azaspirocycles'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "1-Azaspirocycles"

1

Robinson, Andrea, Zhen Wang, Nicolas Spiccia, Christopher Gartshore, Jayamini Illesinghe, and William Jackson. "A Concise Cross-Metathesis Route to Enantiopure 1-Azaspirocycles." Synthesis 45, no. 22 (2013): 3118–24. http://dx.doi.org/10.1055/s-0033-1338527.

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2

L. Funk, Raymond, and Joy Umstead Daggett. "Intermolecular Cycloaddition Reactions of Exocyclic Nitrones. Facile Synthesis of 1-Azaspirocycles." HETEROCYCLES 26, no. 8 (1987): 2175. http://dx.doi.org/10.3987/r-1987-08-2175.

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3

Wang, Zhen James, Nicolas Daniel Spiccia, Christopher James Gartshore, Jayamini Illesinghe, William Roy Jackson, and Andrea Jane Robinson. "ChemInform Abstract: A Concise Cross-Metathesis Route to Enantiopure 1-Azaspirocycles." ChemInform 45, no. 15 (2014): no. http://dx.doi.org/10.1002/chin.201415062.

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4

Dake, Gregory. "Recent approaches to the construction of 1-azaspiro[4.5]decanes and related 1-azaspirocycles." Tetrahedron 62, no. 15 (2006): 3467–92. http://dx.doi.org/10.1016/j.tet.2006.01.071.

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5

Ito, Toshimasa, Naoki Yamazaki, and Chihiro Kibayashi. "Synthesis of 1-Azaspirocycles via Lewis Acid-Mediated Spirocyclization of Cyclic N-Acyl-N,O-acetals." Synlett 2001, no. 10 (2001): 1506–10. http://dx.doi.org/10.1055/s-2001-17475.

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6

Ito, Toshimasa, Naoki Yamazaki, and Chihiro Kibayashi. "ChemInform Abstract: Synthesis of 1-Azaspirocycles via Lewis Acid Mediated Spirocyclization of Cyclic N-Acyl-N,O-acetals." ChemInform 33, no. 6 (2010): no. http://dx.doi.org/10.1002/chin.200206152.

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7

Xiao, Kai-Jiong, Jie-Min Luo, Xiao-Er Xia, Yu Wang, and Pei-Qiang Huang. "General One-Pot Reductivegem-Bis-Alkylation of Tertiary Lactams/Amides: Rapid Construction of 1-Azaspirocycles and Formal Total Synthesis of (±)-Cephalotaxine." Chemistry - A European Journal 19, no. 39 (2013): 13075–86. http://dx.doi.org/10.1002/chem.201302096.

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8

Yeh, Ming-Chang P., Cheng-Wei Fang, and Hsin-Hui Lin. "Facile Synthesis of Azaspirocycles via Iron Trichloride-Promoted Cyclization/Chlorination of Cyclic 8-Aryl-5-aza-5-tosyl-2-en-7-yn-1-ols." Organic Letters 14, no. 7 (2012): 1830–33. http://dx.doi.org/10.1021/ol300434m.

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9

Xiao, Kai-Jiong, Jie-Min Luo, Xiao-Er Xia, Yu Wang, and Pei-Qiang Huang. "ChemInform Abstract: General One-Pot Reductive gem-Bis-alkylation of Tertiary Lactams/Amides: Rapid Construction of 1-Azaspirocycles and Formal Total Synthesis of (.+-.)-Cephalotaxine." ChemInform 45, no. 9 (2014): no. http://dx.doi.org/10.1002/chin.201409106.

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10

Yeh, Ming-Chang P., Cheng-Wei Fang, and Hsin-Hui Lin. "ChemInform Abstract: Facile Synthesis of Azaspirocycles via Iron Trichloride Promoted Cyclization/Chlorination of Cyclic 8-Aryl-5-aza-5-tosyl-2-en-7-yn-1-ols." ChemInform 43, no. 31 (2012): no. http://dx.doi.org/10.1002/chin.201231095.

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Dissertations / Theses on the topic "1-Azaspirocycles"

1

Easton, Leah Pearl. "Investigations relevant to semipinacol rearrangements for the formation of 1-azaspirocycles." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/31611.

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Abstract:
Investigations related to semipinacol rearrangements for the formation of 1-azaspirocycles including substrate synthesis, reaction scope, and application to the Erythrina alkaloid skeleton are reported. Nickel(II) and chromium(II) salts are used to promote the addition of enol triflates derived from δ-valerolactam to aldehydes to produce substrates such as A. The use of N-Boc-protected triflate 1.21 results in higher yields than the corresponding N-Ts or N-Bz-protected analogues. Additions to aliphatic aldehydes are most efficient while electron-rich aldehydes prove less reactive. The o
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2

Fenster, Michael David Bengt. "Formation of 1-azaspirocycles via semipinacol rearrangements and its application to the synthesis of fasicularin." Thesis, 2004. http://hdl.handle.net/2429/16876.

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Abstract:
Semipinacol rearrangements forming 1-azaspirocycles as well as a formal synthesis of fasicularin are reported. 1-Azaspirocycles are formed by either an acid mediated semipinacol rearrangement or an epoxide semipinacol rearrangement. Semipinacol rearrangement substrates are prepared from N-para-toluenesulfonyl protected lactams. 1-Azaspiro[5.4]decanones (a) are formed in high yield and moderate to excellent diastereoselectivity via acid mediated semipinacol rearrangement of substrates resembling b. Unfortunately, larger cyclic systems (such as c) are not formed using this method due to competin
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