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Relevant bibliographies by topics / 11α- hydroxyprogesterone

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Academic literature on the topic '11α- hydroxyprogesterone'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "11α- hydroxyprogesterone"

1

Lai, Tian Chao, Yun Dai, Bin Zhou, Guang Jian Shen, Hai Lin Su, and Gang Du. "Microbial Hydroxylation of Progesterone with Aspergillus ustus." Advanced Materials Research 807-809 (September 2013): 410–13. http://dx.doi.org/10.4028/www.scientific.net/amr.807-809.410.

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Progesterone was biotransformed byAspergillus ustusin this paper. Two products were obtained and they were identified as 11α-hydroxyprogesterone and 11α,15β-dihydroxyprogesterone by NMR and MS. The fermentation process of biotransformtion had been studied with HPLC and 11α-hydroxyprogesterone was the main product.

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2

Kozłowska, Ewa, Jordan Sycz, and Tomasz Janeczko. "Hydroxylation of Progesterone and Its Derivatives by the Entomopathogenic Strain Isaria farinosa KCh KW1.1." International Journal of Molecular Sciences 23, no. 13 (2022): 7015. http://dx.doi.org/10.3390/ijms23137015.

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Progesterone biotransformation is worth studying because of the high industrial value of its derivatives. This study investigated the catalytic ability of the entomopathogenic filamentous fungus strain Isaria farinosa KCh KW1.1 to transform progesterone derivatives: 11α-hydroxyprogesterone, 17α-hydroxyprogesterone, 16α,17α-epoxyprogesterone and pregnenolone. In the culture of Isaria farinosa KCh KW1.1, 11α-hydroxyprogesterone was effectively transformed into only one product: 6β,11α-dihydroxyprogesterone. Transformation of 17α-hydroxyprogesterone gave three hydroxy derivatives: 6β,17α-dihydrox

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3

Nickavar, Bahman, Hossein Vahidi та Mehrnoosh Eslami. "An efficient biotransformation of progesterone into 11α-hydroxyprogesterone by Rhizopus microsporus var. oligosporus". Zeitschrift für Naturforschung C 74, № 1-2 (2018): 9–15. http://dx.doi.org/10.1515/znc-2018-0092.

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Abstract Rhizopus microsporus var. oligosporus is a fungus that belongs to the Mucoraceae family that is used for the preparation of some soy-fermented foods. Microbial biotransformation of progesterone by R. microsporus var. oligosporus afforded some monohydroxylated and dihydroxylated metabolites. The main product was purified using chromatographic methods and identified as 11α-hydroxyprogesterone on the basis of its spectroscopic features. Time course studies by high-performance thin-layer chromatography demonstrated that this fungi efficiently hydroxylated progesterone at the 11α-position

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4

Choudhary, Muhammad Iqbal, Muhammad Nasir, Shamsun N. Khan та ін. "Microbial Hydroxylation of Hydroxyprogesterones and α-Glucosidase Inhibition Activity of Their Metabolites". Zeitschrift für Naturforschung B 62, № 4 (2007): 593–99. http://dx.doi.org/10.1515/znb-2007-0419.

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Microbial transformation of 11α-hydroxyprogesterone (1) with Cunninghamella elegans, Gibberella fujikuroi, Fusarium lini, and Candida albicans yielded 11α,15α,16α-trihydroxypregn-4- ene-3,20-dione (3), 11α-hydroxy-5α-pregnane-3,20-dione (4), 6β ,11α-dihydroxypregn-4-ene-3,20- dione (5), 11α-hydroxypregna-1,4-diene-3,20-dione (6), 11α,17β -dihydroxyandrost-4-en-3-one (7), and 11α,15α-dihydroxypregn-4-ene-3,20-dione (8). On the other hand, microbial transformation of 17α-hydroxyprogesterone (2) with Cunninghamella elegans and Fusarium lini yielded 11α,17α- dihydroxypregn-4-ene-3,20-dione (9), an

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5

Yoshida, Hirokazu, Shiro Nakai, Fusako Nimbari, Kiyoko Yoshimoto та Tadashi Nishimura. "Synthesis of 11α-hydroxyprogesterone hartens". Steroids 53, № 6 (1989): 727–38. http://dx.doi.org/10.1016/0039-128x(89)90063-9.

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6

Kasal, Alexander, та Světlana Pásztorová. "Synthesis of RIA Haptens: 3α,11α-Dihydroxy-5α-pregnan-20-one 11-Hemisuccinate". Collection of Czechoslovak Chemical Communications 58, № 3 (1993): 619–28. http://dx.doi.org/10.1135/cccc19930619.

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5α-Pregnane-3α,11α-diol-20-one (XVII) was prepared by hydroxylation of 5α-pregnan-3α-ol-20-one (XVI) by Rhizopus nigricans and by chemical conversion of 11α-hydroxyprogesterone (I). The diol XVII was partially acylated with 2-(trimethylsilyl)ethyl hydrogen succinate and the 11α-succinate XVIII was converted to the target 11α-hemisuccinate XXI.

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7

Du, Gang, Tian Chao Lai, Hai Ying Yang, Jing Xian Sun, Ming Hong Chen, and Guang Qiu Zhang. "Microbial Hydroxylation of Progesterone with Phomopsis Sp." Advanced Materials Research 781-784 (September 2013): 1168–71. http://dx.doi.org/10.4028/www.scientific.net/amr.781-784.1168.

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Microbial hydroxylation of progesterone occurred in the biotransformation by Phomopsis sp.. The conversion products were purified by column chromatography with ether/EtOAc and characterized by spectroscopic methods including 1HNMR, 13C NMR, IR, UV and MS. Those conversion products were identified as 11α-hydroxyprogesterone (2), 11α,15β-dihydroxy progesterone (3),11α-dihydroxypreg-1,4-dien-3,20-dione (4), 6β,15βdihydroxypregesterone (5) and 7β,15βdihydroxypregesterone (6).

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8

Yamaguchi, Tokutaro, Joo-Ho Lee, A. Rang Lim, Eun-Ji Yu та Tae-Jin Oh. "Biotransformation into 11α-hydroxyprogesterone glucosides by glucosyltransferase". Steroids 145 (травень 2019): 32–38. http://dx.doi.org/10.1016/j.steroids.2019.02.008.

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9

Yildirim, Kudret, Ilknur Kupcu, and Fatih Gulsan. "Biotransformation of Some Steroids by Aspergillus wentii." Zeitschrift für Naturforschung C 65, no. 11-12 (2010): 688–92. http://dx.doi.org/10.1515/znc-2010-11-1209.

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First steroid biotransformations performed by Aspergillus wentii MRC 200316 are reported. Testosterone (1) yields 6β-hydroxytestosterone (3) and 14α-hydroxytestosterone (4) while progesterone (2) yields 11α-hydroxyprogesterone (5).

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10

Al-Awadi, Sameera, Mohammed Afzal та Sosamma Oommen. "Studies onGeobacillus stearothermophilus– Part V: Transformation of 11α-hydroxyprogesterone". Biocatalysis and Biotransformation 23, № 5 (2005): 323–28. http://dx.doi.org/10.1080/10242420500285710.

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Dissertations / Theses on the topic "11α- hydroxyprogesterone"

1

Sykes, Karen L. Vestergaard. "Effect of 6α-methyl-17α hydroxyprogesterone acetate on uterine secretion of prostaglandin (PG) F₂α and luteal sensitivity to exogenous PGF₂α". Thesis, Virginia Tech, 1995. http://hdl.handle.net/10919/41031.

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2

Petzold, Verena [Verfasser]. "Aufbau und Evaluierung eines Chemilumineszenz-Immunoassays zur Bestimmung von 17α-Hydroxyprogesteron [17-alpha-Hydroxyprogesteron] im Serum mittels eines 7α-biotinylierten {17α-Hydroxyprogesteron-Tracers [7-alpha-biotinylierten 17-alpha-Hydroxyprogesteron-Tracers] / Verena Petzold". 2000. http://d-nb.info/962102296/34.

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3

Grigull, Andreas [Verfasser]. "Adrenale Steroide bei der Adrenomyeloneuropathie : Dehydroepiandrosteron, 17α-Hydroxyprogesteron [17-Alpha-Hydroxyprogesteron] und Androstendion / vorgelegt von: Andreas Grigull". 2007. http://d-nb.info/985018968/34.

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Book chapters on the topic "11α- hydroxyprogesterone"

1

Szyczewski, A., and R. Krzyminiewski. "Radical Structure in — Irradiated Single Crystal of 17α- Hydroxyprogesterone." In Organic Free Radicals. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73963-7_100.

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2

"Fall 8 Säugling mit Klitorishypertropie und erhöhtem 17α−Hydroxyprogesteron." In Fallbuch Biochemie, edited by Timo Brandenburger and Tido Bajorat. Georg Thieme Verlag, 2006. http://dx.doi.org/10.1055/b-0034-27746.

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