Academic literature on the topic '18F–fluoro-deoxy-glucose-PET'

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Journal articles on the topic "18F–fluoro-deoxy-glucose-PET"

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Medak, Adrianna, Julia Wojtowicz, Katarzyna Pietrasz, et al. "Użyteczność badania 18F-FDG PET/CT w diagnostyce guzów pierwotnych i przerzutów nowotworowych do mózgu." Letters in Oncology Science 17, no. 3 (2020): 1–7. http://dx.doi.org/10.21641/los.2020.17.3.183.

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Celem niniejszej pracy jest wykazanie, że mimo nieswoistego charakteru radiofarmaceutyku 2-deoxy-2-[18F]fluoro-D-glukozy (z ang. 2-deoxy-2-[18F]fluoro-D-glucose, 18F-FDG), badanie pozytonowej tomografii emisyjnej/tomografii komputerowej (z ang. positron emission tomography/computed tomography, PET/CT) z użyciem 18F-FDG pozwala wykryć guzy pierwotne i przerzuty nowotworowe do mózgu, co może znacząco wpłynąć na protokół terapeutyczny i jakość życia chorego onkologicznie.
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Kairemo, Kalevi, Elmer B. Santos, Homer A. Macapinlac, and Vivek Subbiah. "Early Response Assessment to Targeted Therapy Using 3′-deoxy-3′[(18)F]-Fluorothymidine (18F-FLT) PET/CT in Lung Cancer." Diagnostics 10, no. 1 (2020): 26. http://dx.doi.org/10.3390/diagnostics10010026.

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Although 2-deoxy-2-[18F]-fluoro-D-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) is a sensitive nuclear medicine modality, specificity for characterizing lung cancer is limited. Tumor proliferation and early response to molecularly targeted therapy could be visualized using 3′-deoxy-3′[(18)F]-fluorothymidine (18F-FLT) PET/CT. The superiority of 18F-FLT PET/CT over 18F-FDG PET/CT in early therapeutic monitoring has been well described in patients after chemotherapy, radiotherapy, and/or chemo/radiotherapy. In thispilot study, we explorethe use of 18F-FLT PET/CT as an
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Munter-Young, Regina, Adolfo Fuentes-Alburo, Nicholas DiGregorio, Kurt Neeser, and Dmitry Gultyaev. "Clinical and economic outcomes of adding [18F]FES PET/CT in estrogen receptor status identification in metastatic and recurrent breast cancer in the US." PLOS ONE 19, no. 5 (2024): e0302486. http://dx.doi.org/10.1371/journal.pone.0302486.

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Background and objectives Correct identification of estrogen receptor (ER) status in breast cancer (BC) is crucial to optimize treatment; however, standard of care, involving biopsy and immunohistochemistry (IHC), and other diagnostic tools such as 2-deoxy-2-[18F]fluoro-D-glucose or 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG), can yield inconclusive results. 16α-[18F]fluoro-17β-fluoroestradiol ([18F]FES) can be a powerful tool, providing high diagnostic accuracy of ER-positive disease. The aim of this study was to estimate the budget impact and cost-effectiveness of adding [18F]FES PET/CT to bi
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Huellner, M. W., M. Cousin, T. Linder, et al. "Melanoma of the middle ear: initial presentation, Fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography imaging and follow up." Journal of Laryngology & Otology 125, no. 5 (2011): 536–39. http://dx.doi.org/10.1017/s0022215110002872.

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AbstractBackground:We present a rare case of primary mucosal melanoma of the middle ear imaged with 18F-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT).Method:Clinical, radiological, intra-operative and histological findings are discussed.Results:An 88-year-old woman presented with intermittent otorrhoea of the left ear for several months. Otoscopy revealed a livid protrusion of the tympanic membrane. Melanoma was not suspected initially, but was established on transmembranous biopsy. Pre-operative 18F-fluoro-2-deoxy-d-glucose positron emission tomography
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Zhang-Yin, Jules, Antoine Girard, Etienne Marchal, et al. "PET Imaging in Bladder Cancer: An Update and Future Direction." Pharmaceuticals 16, no. 4 (2023): 606. http://dx.doi.org/10.3390/ph16040606.

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Molecular imaging with positron emission tomography is a powerful tool in bladder cancer management. In this review, we aim to address the current place of the PET imaging in bladder cancer care and offer perspectives on potential future radiopharmaceutical and technological advancements. A special focus is given to the following: the role of [18F] 2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography in the clinical management of bladder cancer patients, especially for staging and follow-up; treatment guided by [18F]FDG PET/CT; the role of [18F]FDG PET/MRI, the other PET radiopharmaceu
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Honka, Miikka-Juhani, Eleni Rebelos, Simona Malaspina, and Pirjo Nuutila. "Hepatic Positron Emission Tomography: Applications in Metabolism, Haemodynamics and Cancer." Metabolites 12, no. 4 (2022): 321. http://dx.doi.org/10.3390/metabo12040321.

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Evaluating in vivo the metabolic rates of the human liver has been a challenge due to its unique perfusion system. Positron emission tomography (PET) represents the current gold standard for assessing non-invasively tissue metabolic rates in vivo. Here, we review the existing literature on the assessment of hepatic metabolism, haemodynamics and cancer with PET. The tracer mainly used in metabolic studies has been [18F]2-fluoro-2-deoxy-D-glucose (18F-FDG). Its application not only enables the evaluation of hepatic glucose uptake in a variety of metabolic conditions and interventions, but based
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Pietrzak, Agata, Andrzej Marszałek, Tomasz Piotrowski, et al. "Primary and Metastatic Brain Tumours Assessed with the Brain and Torso [18F]FDG PET/CT Study Protocol—10 Years of Single-Institutional Experiences." Pharmaceuticals 14, no. 8 (2021): 722. http://dx.doi.org/10.3390/ph14080722.

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According to the international societies’ recommendations, the 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography/computed tomography ([18F]FDG PET/CT) technique should not be used as the method of choice in brain tumour diagnosis. Therefore, the brain region can be omitted during standard [18F]FDG PET/CT scanning. We performed comprehensive literature research and analysed results from 14,222 brain and torso [18F]FDG PET/CT studies collected in 2010–2020. We found 131 clinically silent primary and metastatic brain tumours and 24 benign lesions. We concluded that the brain and torso
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Adamcová, Vanda, Klára Kuglerová, Katarína Ondreičková, et al. "Visualization and quantification of 2-deoxy-2-fluoro[18F]-D-glucose in plant tissues by a commercial PET system." Nova Biotechnologica et chimica 19, no. 1 (2020): 98–108. http://dx.doi.org/10.36547/nbc.v19i1.582.

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Some works showed that commercial PET systems and 2-deoxy-2-fluoro[18F]-D-glucose (2-[18F]FDG) can be used in plant studies to analyze the transport and allocation of photoassimilates. The aim of this work was to evaluate the effect of characteristics of plant tissues, applied solution and the phenomenon of “escaping positrons” on the visualisation and quantification of the uptake and distribution
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Zhang, Xiang, Falguni Basuli, Zhen-Dan Shi, et al. "Synthesis and Evaluation of Fluorine-18-Labeled L-Rhamnose Derivatives." Molecules 28, no. 9 (2023): 3773. http://dx.doi.org/10.3390/molecules28093773.

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The use of radiolabeled glucose for PET imaging resulted in the most commonly used tracer in the clinic, 2-deoxy-2-[18F]fluoroglucose (FDG). More recently, other radiolabeled sugars have been reported for various applications, including imaging tumors and infections. Therefore, in this study, we developed a series of fluorine-18-labeled L-rhamnose derivatives as potential PET tracers of various fungal and bacterial strains. Acetyl-protected triflate precursors of rhamnose were prepared and radiolabeled with fluorine-18 followed by hydrolysis to produce L-deoxy [18F]fluororhamnose. The overall
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Sheikhbahaei, Sara, Rathan M. Subramaniam, and Lilja B. Solnes. "2-Deoxy-2-[18F] Fluoro-d-Glucose PET/Computed Tomography." PET Clinics 17, no. 2 (2022): 307–17. http://dx.doi.org/10.1016/j.cpet.2021.12.003.

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Dissertations / Theses on the topic "18F–fluoro-deoxy-glucose-PET"

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Schmaderer, Christoph. "Evaluation Voxel-basierter Methoden der statistischen Analyse des regionalen cerebralen Glucosestoffwechsels bei Morbus-Huntington-Patienten eine Positronen-Emissions-Tomographie (PET)-Studie mit 18F-Fluoro-Deoxy-Glucose (18FDG) /." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=971282226.

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Schmaderer, Christoph [Verfasser]. "Evaluation Voxel-basierter Methoden der statistischen Analyse des regionalen cerebralen Glucosestoffwechsels bei Morbus-Huntington-Patienten : eine Positronen-Emissions-Tomographie (PET)-Studie mit 18F-Fluoro-Deoxy-Glucose (18FDG) / Christoph Schmaderer." 2004. http://d-nb.info/971282226/34.

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Book chapters on the topic "18F–fluoro-deoxy-glucose-PET"

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Mosconi Lisa, Berti Valentina, McHugh Pauline, Pupi Alberto, and de Leon Mony J. "A Tale of Two Tracers: Glucose Metabolism and Amyloid Positron Emission Tomography Imaging in Alzheimer's Disease." In Advances in Alzheimer’s Disease. IOS Press, 2011. https://doi.org/10.3233/978-1-60750-793-2-219.

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The development of prevention therapies for Alzheimer's disease (AD) would greatly benefit from biomarkers that are sensitive to subtle brain changes occurring prior to the onset of clinical symptoms, when the potential for preservation of function is at the greatest. In vivo brain imaging is a promising tool for the early detection of AD through visualization of abnormalities in brain structure, function and histopathology. Currently, Positron Emission Tomography (PET) imaging with amyloid-beta (Aβ) tracers and 2-[18F]fluoro-2-Deoxy-D-glucose (FDG) is largely utilized in the early an
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Fernandes, Mariana, Agostino Chiaravalloti, Natalia Manfredi, et al. "Nocturnal Hypoxia and Sleep Fragmentation May Drive Neurodegenerative Processes: The Compared Effects of Obstructive Sleep Apnea Syndrome and Periodic Limb Movement Disorder on Alzheimer’s Disease Biomarkers." In Handbook of Prevention and Alzheimer’s Disease. IOS Press, 2024. http://dx.doi.org/10.3233/aiad230032.

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Background: Sleep disorders may cause dysregulation in cerebral glucose metabolism and synaptic functions, as well as alterations in cerebrospinal fluid (CSF) biomarker levels. Objective: This study aimed at measuring sleep, CSF Alzheimer’s disease (AD) biomarkers, and cerebral glucose consumption in patients with obstructive sleep apnea syndrome (OSAS) and patients with periodic limb movement disorder (PLMD), compared to controls. Methods: OSAS and PLMD patients underwent 18F-fluoro-2-deoxy-D-glucose positron emission tomography (18F-FDG PET), polysomnographic monitoring, and lumbar puncture
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Høilund-Carlsen, Poul F., Abass Alavi, and Jorge R. Barrio. "PET/CT/MRI in Clinical Trials of Alzheimer’s Disease." In Advances in Alzheimer’s Disease. IOS Press, 2024. https://doi.org/10.3233/aiad240044.

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With the advent of PET imaging in 1976, 2-deoxy-2-[18F]fluoro-D-glucose (FDG)-PET became the preferred method for in vivo investigation of cerebral processes, including regional hypometabolism in Alzheimer’s disease. With the emergence of amyloid-PET tracers, [11C]Pittsburgh Compound-B in 2004 and later [18F]florbetapir, [18F]florbetaben, and [18F]flumetamol, amyloid-PET has replaced FDG-PET in Alzheimer’s disease anti-amyloid clinical trial treatments to ensure “amyloid positivity” as an entry criterion, and to measure treatment-related decline in cerebral amyloid deposits. MRI has been used
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Subburaj, Kiruthika, Venkata Subramanian Krishnaraju, and Anjugam Alagappan. "Radiopharmaceuticals in Dermatologic Imaging and Therapy." In Targeted Radiopharmaceuticals and Imaging. Royal Society of Chemistry, 2025. https://doi.org/10.1039/9781837677139-00382.

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Skin is an organ system, which includes not only the skin but also its associated appendages, like hair and nails. These are sites of a wide range of both benign and malignant disease processes. Nuclear medicine plays a vital role in diagnosis, prognostication, response assessment and surveillance of malignant conditions, such as melanoma and other non-melanoma skin cancers. [18F]2-fluoro-2-deoxy glucose ([18F]FDG) positron emission tomography (PET)–computerized tomography (CT) is the cornerstone of oncology practice and is supplemented by a wide variety of newly developed radiopharmaceuticals
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Triumbari, Elizabeth Katherine Anna, Agostino Chiaravalloti, Orazio Schillaci, Nicola Biagio Mercuri, and Claudio Liguori. "Positron Emission Tomography/Computed Tomography Imaging in Therapeutic Clinical Trials in Alzheimer’s Disease: An Overview of the Current State of the Art of Research." In Advances in Alzheimer’s Disease. IOS Press, 2024. https://doi.org/10.3233/aiad240045.

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The integration of positron emission tomography/computed tomography (PET/CT) has revolutionized the landscape of Alzheimer’s disease (AD) research and therapeutic interventions. By combining structural and functional imaging, PET/CT provides a comprehensive understanding of disease pathology and response to treatment assessment. PET/CT, particularly with 2-deoxy-2-[fluorine-18]fluoro-D-glucose (18F-FDG), facilitates the visualization of glucose metabolism in the brain, enabling early diagnosis, staging, and monitoring of neurodegenerative disease progression. The advent of amyloid and tau PET
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King, KS, DK Alexopoulos, MA Whatley, et al. "Functional Imaging of Head and Neck Paragangliomas: Comparison of18F-Fluorodihydroxyphenylalanine (18F-FDOPA) Positron Emission Tomography (PET),18F-Fluorodopamine (18F-FDA) PET/Computed Tomography (CT),18F-Fluoro-2-Deoxy-D-Glucose (18F-FDG) PET/CT,123I-Metaiodobenzylguanidine (123I-MIBG) Scintigraphy, and 111In-Pentetreotide Scintigraphy." In The Endocrine Society's 92nd Annual Meeting, June 19–22, 2010 - San Diego. Endocrine Society, 2010. http://dx.doi.org/10.1210/endo-meetings.2010.part2.or.or14-2.

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Faheem, Mohd, Vaibhav Pandey, and Manish Dixit. "[ 18F]Fluoro Analogue of D-Glucose: A Chemistry Perspective." In 2-Deoxy-D-Glucose: Chemistry and Biology. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815305159124010007.

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2-[18F]fluoro-D-glucose ([18F]FDG) is a versatile molecule in nuclear medicine that has evolved into a vital radiotracer in medical imaging applications via positron emission tomography (PET) [18F]FDG is derived from its derivative, 2-deoxyD-glucose (2-DG), where the triflate group is attached to carbon-2 [18F]FDG serves as a crucial non-invasive diagnostic tool and is prominently utilized in non-invasive imaging of various metastatic diseases, particularly cancer imaging. Its importance as a tracer has been further enhanced by its unexpected attribute of generating a low body background throu
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Conference papers on the topic "18F–fluoro-deoxy-glucose-PET"

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Patel, Maryam, Bawanile Hadebe, Venesen Pillay, and Lerwine Harry. "Should 18F-FDG PET/CT Scans (2-Deoxy-2[fluorine 18] fluoro-D-glucose Integrated with Computed Tomography) Replace 99mTc-MDP (Methylene Diphosphonate) Bone Scintigraphy in the Management of Breast Cancer Patients with Suspected Skeletal Metastases?" In Abstracts for the 18th International Conference on Radiopharmaceutical Therapy (ICRT). Thieme Medical and Scientific Publishers Pvt. Ltd., 2023. http://dx.doi.org/10.1055/s-0043-1769982.

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