Academic literature on the topic '2-b]pyrrole'

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Journal articles on the topic "2-b]pyrrole"

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Sleziak, Róbert, Slávka Balážiová, and Alžbeta Krutošíková. "Reactions of Furo[2,3-b]pyrrole and Furo[3,2-b]pyrrole-Type Aldehydes." Collection of Czechoslovak Chemical Communications 64, no. 7 (1999): 1135–46. http://dx.doi.org/10.1135/cccc19991135.

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The synthesis of methyl 2-formyl-6-(methoxymethyl)furo[2,3-b]pyrrole-5-carboxylate (1d) is described. The reactions of methyl 2-formylfuro[2,3-b]pyrrole-5-carboxylates 1a-1d with malononitrile afforded methyl 2-(2,2-dicyanovinyl)furo[2,3-b]pyrrole-5-carboxylates 3a-3d, with methyl cyanoacetate methyl 2-[2-cyano-2-(methoxycarbonyl)vinyl]furo[2,3-b]pyrrole-5-carboxylates 4a-4d and with 2-furylacetonitrile methyl 2-[2-cyano-2-(2-furyl)vinyl]furo[2,3-b]pyrrole-5-carboxylates 5a-5d. Compounds 1b-1d and methyl azidoacetate gave the appropriate vinylazides 6b-6d, which were used for preparation of su
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Zemanová, Ivana, and Renata Gašparová. "SYNTHESIS AND REACTIONS OF NEW DERIVATIVES OF FURO[3,2-b]PYRROLE." Nova Biotechnologica et Chimica 12, no. 2 (2013): 100–107. http://dx.doi.org/10.2478/nbec-2013-0012.

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Abstract Synthesis of methyl 4H-furo[3,2-b]pyrrole-5-carboxylate is taken place in two step synthesis. Vilsmeier-Haack reaction of 4H-furo[3,2-b]pyrrole-5-carboxylate 1 led to methyl 2-formyl-4H-furo[3,2- b]pyrrole-5-carboxylate 4, which served as starting compound for synthesis of furo[3,2-b]pyrrole-2- aldoxime 5 and methyl 2-[(4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-4H-furo[3,2-b]pyrrole-5- carboxylate 7. The hydrazinolysis of 1 was prepared by carbohydrazide 2, which subsequently reacted with aldehydes to form of derivatives 3. Pyrazole derivatives 11 were prepared by the reaction
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Krutošíková, Alžbeta, Miloslava Dandárová, and Vladimír Bobošík. "Derivatives of Furo[3,2-b]pyrrole." Collection of Czechoslovak Chemical Communications 59, no. 2 (1994): 473–81. http://dx.doi.org/10.1135/cccc19940473.

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A number of methyl 2-substituted, 2,3-disubstituted-4H-furo[3,2-b]pyrrole-5-carboxylates (V - VII) and methyl 1H-benzo[b]furo[3,2-b]pyrrole-2-carboxylate (VIII) was prepared by the thermolysis of corresponding methyl 2-azido-3-(R1,R2-substituted-2-furyl)propenoates (I - IV). N-Methyl and N-benzyl derivatives IX - XVI were prepared at the phase-transfer catalysis conditions. Hydrolysis of some N-methyl and N-benzyl substituted esters furnished corresponding acids XVII - XXII. The hydrazides XXIII - XXX were obtained from corresponding esters and hydrazine hydrate. The preparation of 1-benzylben
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Ebada, Sherif Saeed, RuAngelie Edrada-Ebel, Nicole J. de Voogd, Victor Wray, and Peter Proksch. "Dibromopyrrole Alkaloids from the Marine Sponge Acanthostylotella sp." Natural Product Communications 4, no. 1 (2009): 1934578X0900400. http://dx.doi.org/10.1177/1934578x0900400112.

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Fourteen dibromopyrrole alkaloids were isolated from the marine sponge Acanthostylotella sp. collected in Indonesia. In addition to the known compounds 4,5-dibromo-N-(methoxy-methyl)-1 H-pyrrole-2-carboxamide (7), 4,5-dibromo-1 H-pyrrole-2-carboxamide (8), mukanadin D (9), (±)-longamide B methyl ester (10), (±)-longamide B (11), (±)-longamide (12), 3,4-dibromo-1 H-pyrrole-2-carboxamide (13), 2-cyano-4,5-dibromo-1 H-pyrrole (14), six compounds were isolated that proved to be new natural products including acanthamides A – D (1 – 4), methyl 3,4-dibromo-1 H-pyrrole-2-carboxylate (5) and 3,5-dibro
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Harris, RLN, and HG Mcfadden. "Fused Heterocycles From Pyrrolethiols. Thieno[2,3-B]Pyrroles, Thieno[3,2-B]Pyrroles and Thiazolo[3,2-a]Pyrroles From Pyrrol-2-Yl Phenacyl Sulfides." Australian Journal of Chemistry 39, no. 6 (1986): 887. http://dx.doi.org/10.1071/ch9860887.

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A reinvestigation of the cyclization of pyrrol-2-yl phenacyl sulfides in polyphosphoric acid has shown that the major product is a thieno[3,2-b]pyrrole, where rearrangement of the sulfur substituent from position 2 to position 3 has preceded cyclization. When TiCl4 is used as cyclocondensation reagent minimal rearrangement is observed and the product obtained is either a thiazolo[3,2-a]pyrrole when the pyrrole nitrogen is unsubstituted, or a thieno[2,3-b]pyrrole where an N-substituent is present.
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Kraľovičová, Eva, Alžbeta Krutošíková, Jaroslav Kováč, and Miloslava Dandárová. "Electrophilic substitution reactions of furo[3,2-b]pyrrole derivatives." Collection of Czechoslovak Chemical Communications 51, no. 1 (1986): 106–11. http://dx.doi.org/10.1135/cccc19860106.

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Formylation of ethyl 4H-furo[3,2-b]pyrrole-5-carboxylate and its N-methyl analogue afforded the 2-formyl products Ia,b which on nitration yielded 2-nitro derivatives IIc,d. Formylation, nitration, Mannich reaction, and copulation of the starting products, having position 2 occupied by an aryl, took place at the pyrrole ring.
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Torosyan, S. A., Z. F. Nuriakhmetova, F. A. Gimalova, and M. S. Miftakhov. "Synthesis of new 1,3,4-oxadiazole and 1,2,3-triazole derivatives based on thieno[3,2-<i>b</i>]pyrrolecarboxylic acid." Журнал органической химии 59, no. 2 (2023): 266–70. http://dx.doi.org/10.31857/s0514749223020143.

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Starting from 4-benzylthieno[3,2- b ]pyrrole-5-carboxylic acid hydrazide and 4-(2-propyn-1-yl)thieno[3,2- b ]pyrrole-5-carboxylic acid methyl ester new 1,3,4-oxadiazole and 1,2,4-triazole derivatives were obtained.
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Krutošíková, Alžbeta, and Mikuláš Hanes. "Substituted 4-Benzylfuro[3,2-b]pyrroles." Collection of Czechoslovak Chemical Communications 57, no. 7 (1992): 1487–94. http://dx.doi.org/10.1135/cccc19921487.

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Preparation of 4-benzylfuro[3,2-b]pyrroles is described and their reactions with selected dienophiles are discussed. Utilization of 4-acetylfuro[3,2-b]pyrroles for preparation of 4-substituted derivatives of furo[3,2-b]pyrrole and the synthesis of ethyl 4-(2- and 4-nitrobenzyl)furo[3,2-b]pyrrole-5-carboxylates for fusing to a 1,4-diazepine system is presented.
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Mai, Huyen Le Thi, Nhung Thanh Thi Truong, Thiet Quoc Nguyen, et al. "Synthesis and characterization of donor–acceptor semiconducting polymers containing 4-(4-((2-ethylhexyl)oxy)phenyl)-4H-dithieno[3,2-b:2′,3′-d]pyrrole for organic solar cells." New Journal of Chemistry 44, no. 39 (2020): 16900–16912. http://dx.doi.org/10.1039/d0nj02616f.

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D–A polymers containing 4-(4-((2-ethylhexyl)oxy)phenyl)-4H-dithieno[3,2-b:2′,3′-d]pyrrole and 2,5-bis(2-ethylhexyl)-3,6-di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione were successfully synthesized and applied for organic solar cells.
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Brown, WV, AJ Jones, MJ Lacey, and BP Moore. "Chemistry of buprestins A and B. Bitter principles of jewel beetles (Coleoptera: Buprestidae)." Australian Journal of Chemistry 38, no. 1 (1985): 197. http://dx.doi.org/10.1071/ch9850197.

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The isolation an structural elucidation of β-D- glucopyranose 1,2,6- tris (pyrrole-2-carboxylate) ( buprestin A) (1) and β-D- glucopyranose 6- (4-hydroxybenzoate) 1,2-bis(pyrrole-2-carboxylate) ( buprestin B) (3), bitter principles of beetles of the family Buprestidae , are reported.
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Dissertations / Theses on the topic "2-b]pyrrole"

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Lin, Chia-I., and 林佳誼. "Part 1. A Mechanistic Study of Pyreno[2,1-b]pyrrole and Bis(pyreno[2,1-b]pyrrole) as Selective Chemosensors of Fluoride IonPart 2. Synthesis of Adenosine Analogues for Therapy of Huntington’s Disease." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/42509461099923724744.

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碩士<br>國立臺灣大學<br>化學研究所<br>95<br>Part 1. A Mechanistic Study of Pyreno[2,1-b]pyrrole and Bis(pyreno[2,1-b]pyrrole) as Selective Chemosensors of Fluoride Ion Pyreno[2,1-b]pyrrole and its dimeric derivative display excellent selectivity and sensitivity for detection of fluoride ion, in comparison with other anions. The bonding with fluoride ion, both in formation and in subsequent dissociation, provides remarkable colorimetric and fluorescent changes in the visible region that are advantageous for real-time and on-site application. The mechanisms of detection were also investigated by detailed NMR
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Chen, Jian-Wei, and 陳建偉. "Di(1-benzothieno)[3,2-b:2′,3′-d]pyrrole-Based Copolymer for Efficient Organic Solar Cell Applications." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/9czyf2.

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碩士<br>逢甲大學<br>纖維與複合材料學系<br>106<br>A tailor-made donor–π–acceptor (D–π–A) copolymer comprising of a novel di(1-benzothieno)[3,2-b:2’,3’-d]pyrrole (DBTP) moiety and a strong electron-accepting diketopyrrolopyrrole (DPP) segment with thi-ophene π-bridge units has been synthesized by Stille coupling polymer-ization and thoroughly characterized for use as a p-type semiconducting polymer. A comprehensive study of the structure-function relationship in the polymer solar cells was also explored. In addition, charge recom-bination behavior is another critical factor that could have great influ-ence on
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Lin, Chia-I. "Part 1. A Mechanistic Study of Pyreno[2,1-b]pyrrole and Bis(pyreno[2,1-b]pyrrole) as Selective Chemosensors of Fluoride Ion Part 2. Synthesis of Adenosine Analogues for Therapy of Huntington's Disease." 2007. http://www.cetd.com.tw/ec/thesisdetail.aspx?etdun=U0001-2107200711402000.

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Book chapters on the topic "2-b]pyrrole"

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Taber, Douglass F. "The Harran Synthesis of (+)-Roseophilin." In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0107.

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Ansa-bridged prodiginines include (+)-roseophilin B 3 and streptorubin B. The observation that streptorubin B potentiated apoptopic signaling in cell culture led to the development of obatoclax, currently being evaluated for the treatment of leukemia. Patrick G. Harran of UCLA devised (J. Am. Chem. Soc. 2013, 135, 3788) what promises to be a general route to the prodiginines, a key step of which was the cyclization of 1 to 2. In planning the synthesis of 1, the authors took advantage of the relative inertness of a monosubstituted alkene. Friedel-Crafts acylation of 5 proceeded smoothly without
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Zaier, Rania, and Sahbi Ayachi. "Computational Study on Optoelectronic Properties of Donor-Acceptor Type Small π-Conjugated Molecules for Organic Light-Emitting Diodes (OLEDs) and Nonlinear Optical (NLO) Applications." In Density Functional Theory - Recent Advances, New Perspectives and Applications. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.98590.

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Recently, donor-acceptor type molecule that contains electron-rich (D) and electron-deficient (A) moiety has emerged as an interesting approach of molecular design strategy to develop organic light-emitting diodes (OLEDs) and non-linear optical (NLO) devices. In this work, we report a theoretical investigation based on two donor-acceptor (D-A) type small π-conjugated molecules based on dithieno [3,2-b: 2′,3′-d] pyrrole (DTP) and anthracene derivatives. All of the theoretical calculations were performed by Density Functional Theory (DFT) approach at B3LYP/6-31 g(d) level of theory. The structur
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Taber, Douglass F. "Natural Product Synthesis by C–H Functionalization: (±)-Allokainic Acid (Wee), (–)-Cameroonan-7α-ol (Taber), (+)-Lithospermic Acid (Yu), (–)-Manabacanine (Kroutil), Streptorubin B, and Metacycloprodigiosin (Challis)." In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0022.

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Andrew G.H. Wee of the University of Regina showed (Org. Lett. 2010, 12, 5386) that with the bulky BTMSM group on N and the electron-withdrawing pivaloyloxy group deactivating the alternative C–H insertion site, the diazo ketone 1 cleanly cyclized to 2, with 21:1 diastereocontrol. Oxidative cleavage of the arene followed by amide reduction and methylenation of the ketone converted 2 into (±)-allokainic acid 3. Intermolecular C–H insertion was the key step in a complementary route to (±)-kainic acid reported (Org. Lett. 2011, 13, 2674) by Takehiko Yoshimitsu of Osaka University. Rh-mediated int
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Taber, Douglass F. "C–N Ring Construction: The Glorius Synthesis of ent-Monomorine." In Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0054.

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Ryan Gilmour of the Westfälische Wilhelms-Universität Münster employed (Chem. Eur. J. 2014, 20, 794) an organocatalyst to direct the enantioselective aziridination of 1 to 2. Vanessa Kar-Yan Lo and Chi-Ming Che of Hong Kong University devised (Angew. Chem. Int. Ed. 2014, 53, 2982) a Ru catalyst for the enantioselective aziridi­nation (not illustrated) of terminal alkenes. Shu-Li You of the Shanghai Institute of Organic Chemistry and Aiwen Lei of Wuhan University described (Angew. Chem. Int. Ed. 2014, 53, 2443) the Pd-mediated carbonylation of 3 to the β-lactam 4. Professor You reported (J. Am.
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Conference papers on the topic "2-b]pyrrole"

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Shipilovskikh, Sergei A., Irina A. Gorbunova, and Aleksandr E. Rubtsov. "E/Z isomerization of ethyl 2-amino-1-(3-(ethoxycarbonyl)-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-4-oxo-5-(2-oxo-2-phenylethylidene)-4,5-dihydro-1H-pyrrole-3-carboxylate." In PROCEEDINGS OF INTERNATIONAL CONFERENCE ON RECENT TRENDS IN MECHANICAL AND MATERIALS ENGINEERING: ICRTMME 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0018490.

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Hussein, Ola, Feras Alali, Ala-Eddin Al Moustafa, and Ashraf Khalil. "Design, Synthesis and Biological Evaluation of Novel Chalcone Analogs as Potential Therapeutic Agents for Castration-Resistant Prostate Cancer." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0179.

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Prostate cancer (PCa) is the second most frequently diagnosed malignancy, as well as a leading cause of cancer-related mortality in men globally. Despite the initial response to hormonal targeted therapy, the majority of patients ultimately progress to a lethal form of the disease, termed as castration-resistant prostate cancer (CRPC), which currently lacks curative therapeutic options and is associated with poor prognosis. Therefore, the development of novel treatment modalities for PCa is urgently needed. Chalcones, also known as 1,3-diphenyl-2-propen-1-ones, are among the highly attractive
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