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Relevant bibliographies by topics / -[2-(R-phenylimino)-4-methyl-3-(3-[morpholine-4-yl]propyl)-2

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Journal articles

Academic literature on the topic '-[2-(R-phenylimino)-4-methyl-3-(3-[morpholine-4-yl]propyl)-2'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "-[2-(R-phenylimino)-4-methyl-3-(3-[morpholine-4-yl]propyl)-2"

1

Drapak, Іryna, Borys Zimenkovsky, Lina Perekhoda, et al. "Qsar-analysis of 1-[2-(R-phenylimino)-4-methyl-3-(3-[morpholine-4-yl]propyl)-2,3-dihydro-1,3-thiazol-5-yl]ethane-1-one’s derivatives as potential antioxidants." Pharmacia 66, no. 1 (2019): 33–40. http://dx.doi.org/10.3897/pharmacia.66.e35083.

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Aim. The aim of study was to determine of the parameters of the molecular structure of new 1-[2-(R-phenylimino)-4-methyl-3-(3-[morpholine-4-yl]propyl)-2,3-dihydro-1,3-thiazol-5-yl]ethane-1-one derivatives and QSAR-analysis. The latter can be considered as the theoretical basis for de novo design of new potential antioxidants. Materials and methods. 14 new derivatives of 1-[2-(R-phenylimino)-4-methyl-3-(3-[morpholine-4-yl] propyl)-2,3-dihydro-1,3-thiazol-5-yl]ethane-1-one were involved in the study and their antioxidant activities were evaluated. Hyper-Chem 7.59 and BuildQSAR software were used

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2

Drapak, Іryna, Borys Zimenkovsky, Lina Perekhoda, et al. "QSAR-analysis of 1-[2-(R-phenylimino)-4-methyl-3-(3-[morpholine-4-yl]propyl)-2,3-dihydro-1,3-thiazol-5-yl]ethane-1-one's derivatives as potential antioxidants." Pharmacia 66, no. (1) (2019): 33–40. https://doi.org/10.3897/pharmacia.66.e35083.

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Aim. The aim of study was to determine of the parameters of the molecular structure of new 1-[2-(R-phenylimino)-4-methyl-3-(3-[morpholine-4-yl]propyl)-2,3-dihydro-1,3-thiazol-5-yl]ethane-1-one derivatives and QSAR-analysis. The latter can be considered as the theoretical basis for de novo design of new potential antioxidants. Materials and methods. 14 new derivatives of 1-[2-(R-phenylimino)-4-methyl-3-(3-[morpholine-4-yl] propyl)-2,3-dihydro-1,3-thiazol-5-yl]ethane-1-one were involved in the study and their antioxidant activities were evaluated. Hyper-Chem 7.59 and BuildQSAR software were used

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3

Desai, S. N. Mamle, Rudrax N. S. Priolkar, Harshank A. Naik Karmali, Prabhav D. Ambe, and B. S. Biradar. "SYNTHESIS, CHARACTERIZATION AND EVALUATION OF 4-HYDROXY-1-PHENYL/METHYL-3-(3-SUBSTITUTED-1-(SUBSTITUTEDIMINO) PROPYL) QUINOLINE-2(1H)-ONE DERIVATIVES AND 4-HYDROXY-1-PHENYL/METHYL-3-(1-(SUBSTITUEDIMINO) ETHYL) QUINOLINE-2(1H)-ONE DERIVATIVES AS POSSIBLE ANTICANCER AGENTS." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 10 (2017): 240. http://dx.doi.org/10.22159/ijpps.2017v9i10.20184.

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Objective: Synthesis, characterization and evaluation of quinolin-2-one derivatives as possible anticancer agents.Methods: A series of novel 4-hydroxy-1-phenyl/methyl-3-(3-substituted-1-(substitutedimino)propyl)quinolin-2(1H)-one derivatives IIa(1-5)/IIb(1-5) and 4-hydroxy-1-phenyl/methyl-3-(1-(substituedimino)ethyl)quinolin-2(1H)-one derivatives IIIa(1-3)/IIIb(1-3) were synthesised by nucleophilic addition of substituted anilines on 3-acetyl-4-hydroxy-1-phenyl/methylquinolin-2(1H)-one (a/b) and 4-hydroxy-3-(3-substitutedpropanoyl)-1-phenyl/methyl quinolin-2(1H)-one (Ia/Ib); respectively. The

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4

Pranay, Shah, I. Patel R., and J. Vyas P. "Preparation and Biological Screening of Novel Heterocyclic Compounds." International Journal of Trend in Scientific Research and Development 3, no. 3 (2019): 632–36. https://doi.org/10.31142/ijtsrd22815.

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The Pyrimidone derivatives say, N arylidine 6 methyl 2 oxo 4 phenyl 1,2,3, 4 tetrahydropyrimidonecarbohydrazides 2a e were synthesized by condensation of Benzaldehyde derivatives with 6 Methyl 2 oxo 4 phenyl 1,2,3,4 tetrahydro pyrimidone carbohydrazides 1 in good yield. The so called hydrazone were cyclocondensed with succinic anhydride to afford 1 6 methyl 2 oxo 4 phenyl 1,2,3, 4 tetrahydropyrimidone 5 carboxamido 5 oxo 2 aryl pyrrolidine 3 carboxylic acid 3a e . These 3a e on Mannich reaction with formaldehyde and morpholine offered 2 aryl 1 6 methyl 2 oxo 4 phenyl 1, 2, 3, 4 tetrahydropyrim

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5

Mali, Suraj N., Sudhir Sawant, Hemchandra K. Chaudhari, and Mustapha C. Mandewale. "In Silico Appraisal, Synthesis, Antibacterial Screening and DNA Cleavage for 1,2,5-thiadiazole Derivative." Current Computer-Aided Drug Design 15, no. 5 (2019): 445–55. http://dx.doi.org/10.2174/1573409915666190206142756.

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Background: : Thiadiazole not only acts as “hydrogen binding domain” and “two-electron donor system” but also as constrained pharmacophore. Methods:: The maleate salt of 2-((2-hydroxy-3-((4-morpholino-1, 2,5-thiadiazol-3-yl) oxy) propyl) amino)- 2-methylpropan-1-ol (TML-Hydroxy)(4) has been synthesized. This methodology involves preparation of 4-morpholino-1, 2,5-thiadiazol-3-ol by hydroxylation of 4-(4-chloro-1, 2,5-thiadiazol-3-yl) morpholine followed by condensation with 2-(chloromethyl) oxirane to afford 4-(4-(oxiran-2-ylmethoxy)-1,2,5-thiadiazol- 3-yl) morpholine. Oxirane ring of this com

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6

Perekhoda, L. O., H. O. Yeromina, I. V. Drapak, I. A. Sych, A. M. Demchenko та S. O. Komykhov. "The synthesis of N-[4-methyl(41-chlorophenyl)-2-R-phenylіmіnothіazol-3-yl]-morpholine derivatives by Hantzsch reaction". Journal of Organic and Pharmaceutical Chemistry 14, № 3(55) (2016): 52–57. http://dx.doi.org/10.24959/ophcj.16.890.

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7

Suhak, O. A., О. I. Panasenko, and Ye G. Knysh. "Synthesis, physic and chemical properties of 2-(4-R-5-(thiophene-2-ylmethyl)-4h-1,2,4-triazole-3-ylthio)acetate acids and their salts." Farmatsevtychnyi zhurnal, no. 2 (August 14, 2018): 48–54. http://dx.doi.org/10.32352/0367-3057.2.17.06.

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Derivatives of 1,2,4-triazole are inherent in various types of biological activity. They can be used as pesticide and medicinal drugs (anticonvulsants, analgetics, antitumor and antibacterial). In this regard the search of new methods of synthesis and investigation of biological activity of 2-(4-R-5-(thiophene-2-ylmethyl)-4H-1,2,4-triazole-3-ylthio)acetate acids and their salts is relevant nowadays. With the aim of finding the new biologically active compounds 2-(4-R-5-(thiophene-2-ylmethyl)-4H-1,2,4-triazole-3-ylthio)acetate acids and their salts are synthesized, where R is methyl, ethy

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8

Kumar Reddy, G. Mahesh, Raghu Babu Korupolu, B. Kishore Babu, et al. "Hydrolytic Degradation Study of Rivaroxaban: Degradant Products Identification by LC-MS Isolation by Prep-HPLC and Characterization by HRMS, NMR and FT-IR." Asian Journal of Chemistry 32, no. 12 (2020): 3035–42. http://dx.doi.org/10.14233/ajchem.2020.22888.

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Present work illustrates the stress degradation behaviour of rivaroxaban under hydrolytic, oxidative, thermal and photolytic conditions as per ICH guidelines. Under thermal and photolytic conditions drug had a fair stability where as in other stress conditions degradation products were observed. Initial identification of the degradation products was performed by hyphenated mass spectrometry coupled to ultra-performance liquid chromatography (UPLC-MS) and mass directed auto purification (MDAP) was used for isolation. Various 1D and 2D nuclear magnetic resonance (NMR) were performed to character

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9

Anwar, Sh, F. Mahmood, N. A. Tahir, and G. F. Salih. "SECONDARY COMPOUNDS RELEASED BY RHIZOSPHERIC BACTERIA EXHIBIT FUNGISTATIC EFFECTS AGAINST PHYTOPATHOGENIC FUNGUS." IRAQI JOURNAL OF AGRICULTURAL SCIENCES 53, no. 5 (2022): 1174–83. http://dx.doi.org/10.36103/ijas.v53i5.1631.

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The aim of conducted research was to devalute the inhibition effect of metabolites secreted by some Rhizospheric bacteria on the growth of two pathogenic fungi: Rhizoctonia solani and Fussarium solani, 330 bacteria isolates were obtained from the rhizosphere of the wheat, tomato, cowpea and Mt. Atlas mastic tree grown in the Sulaimani. Thirty-five isolates were screened for suppression of phytopathogeneic fungus. Results showed that most of these rhizospheric bacteria were have fungistatic potential in different degrees. The highest inhibition of the linear growth of fungi was noted for R. sol

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10

Fawcett, James A., and Robert G. Harvey. "Proso Millet (Panicum miliaceum) Control in Corn (Zea mays) by Postemergence-Directed Herbicides." Weed Science 36, no. 2 (1988): 215–20. http://dx.doi.org/10.1017/s0043174500074737.

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Proso millet (Panicum miliaceumL. # PANMI) was controlled in corn (Zea maysL. ‘Pioneer 3747’) with postemergence-directed herbicides applied following a standard preplant-incorporated application of butylate[S-ethylbis(2-methylpropyl)carbamothioate] plus dichlormid (2,2-dichloro-N,N-di-2-propenylacetamide) plus cyanazine {2-[[4-chloro-6-(ethylamino)-1,3,5-triazin-2-yl]amino]-2-methylpropanenitrile}. Postemergence-directed applications of ametryn [N-ethyl-N′-(1-methylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine], cloproxydim {(E,E)-2-[1-[[(3-chloro-2-propenyl)oxy]imino]butyl]-5-[2-(ethylthi

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