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Relevant bibliographies by topics / 324.6/23/0941

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Academic literature on the topic '324.6/23/0941'

Author: Grafiati

Published: 26 July 2024

Last updated: 31 July 2025

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Journal articles on the topic "324.6/23/0941"

1

Ebens, Allen J., Leanne Berry, Yung-Hsiang Chen, et al. "A Selective PIM Kinase Inhibitor Is Highly Active In Multiple Myeloma: The Biology of Single Agent and PI3K/AKT/mTOR Combination Activity." Blood 116, no. 21 (2010): 3001. http://dx.doi.org/10.1182/blood.v116.21.3001.3001.

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Abstract Abstract 3001 PIM kinases co-regulate several important elements of the PI3K/AKT/mTOR pathway in myeloma cells (Munugalavadla V. et al., ASH 2010 submitted abstr.). In this study we show that pan-PIM inhibition suppresses growth in myeloma cell lines, xenografts, and primary patient samples, both as a single-agent as well acting synergistically in combination with PI3K, AKT, and mTOR inhibition. The PIM kinases are a family of 3 ser/thr growth factor- & cytokine-induced proteins hypothesized to have redundant survival and growth functions. Although PIM-1,2 have been noted as highl

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2

Tzschoppe, Petra. "Olympische und Paralympische Spiele in Leipzig 2012 – Das Scheitern der Bewerbung und die Folgen." Leipziger Sportwissenschaftliche Beiträge 61, no. 2 (2020): 23–43. https://doi.org/10.5771/0941-5270-2020-2-23.

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3

Барабаш, Юрій. "Проблеми розвитку українського конституціоналізму в аспекті забезпечення незалежності України". State Building and Local Government, SPEC22 (1 листопада 2022): 13–23. https://doi.org/10.31359/1993-0941-2022-1-13-23.

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У статті розглядаються етапи розвитку українського конституціоналізму на предмет виокремлення проблем його розвитку, що впливали на забезпечення незалежності країни. Встановлено, що на кожному етапі конституційно-правового реформування та зміни форми держави в країні виникали проблеми, що безпосередньо впливали на забезпечення незалежності країни і використовувались іншими державами, і переважно росією у її корисних цілях.

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4

Рабінович, Петро. "Львівській лабораторії прав людини – 25 років". State Building and Local Government, SPEC21 (2 грудня 2021): 13–23. https://doi.org/10.31359/1993-0941-2021-1-13-23.

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В статті розглядаються першопричини, обставини та історичний контекст створення Львівської лабораторії прав людини і громадянина у 1996 році на базі тогочасної Академії правових наук України. Окрему увагу в статті приділено детальному розгляду основних результатів дослідницької діяльності лабораторії протягом більше ніж 25 років існування та активності. В тексті представлено широкий спектр проведених досліджень, їх значення та вклад у формування та розвиток прав людини в Україні. В статті розкрито роль Львівської лабораторії прав людини і громадянина у процесі сприяння удосконаленню положень К

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5

Morales, José. "Santiago SANZ SÁNCHEZ, El futuro creador del Dios Trinitario. Un estudio en la Teología Sistemática de Wolfhart Pannenberg, Edicep, Valencia 2007, 221 pp., 16 x 23, ISBN 978-8-4705-0941-4." Scripta Theologica 41, no. 3 (2017): 1005. http://dx.doi.org/10.15581/006.41.13304.

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6

Wandler, Anica M., Benjamin Huang, Alessandro Scacchetti, et al. "Resistant T-Cell Acute Lymphoblastic Leukemias That Emerge after In Vivo Treatment with Dexamethasone Frequently Down-Regulate Glucocorticoid Receptor Protein Expression." Blood 128, no. 22 (2016): 753. http://dx.doi.org/10.1182/blood.v128.22.753.753.

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Abstract Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, with T lineage ALL (T-ALL) accounting for approximately 20% of cases. Many T-ALL patients present with high risk clinical features, and receive aggressive multi-agent genotoxic therapies that pose a substantial risk of long-term adverse health effects. Glucocorticoids (GCs) are an integral part of current treatment strategies for T-ALL and other lymphoid cancers. Despite decades of clinical use, the molecular mechanisms underlying GC efficacy and resistance are incompletely understood. Limited initial response to

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7

Munugalavadla, Veerendra, Leanne Berry, Jae Chang та ін. "A Critical Role for PIM2 Kinase in Multiple Myeloma Through NF-κB Activation". Blood 118, № 21 (2011): 1839. http://dx.doi.org/10.1182/blood.v118.21.1839.1839.

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Abstract Abstract 1839 The PIM kinases are a family of 3 growth factor- & cytokine-induced proteins hypothesized to have redundant survival and growth functions. Although PIM-1, -2 have been noted as highly expressed in multiple myeloma (MM) (Claudio JO et al., 2002), there are few data to support potential therapeutic utility of PIM inhibition in this indication. Here we show that the myeloma cell lines express all PIM protein isoforms to varying extents, and we describe the properties of a novel pan-PIM inhibitor GNE-652 with picomolar biochemical potency, an excellent selectivity profil

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8

Trojani, V., A. Botti, M. Grehn, et al. "OC-0941 STereotactic Arrhythmia Radioablation in Europe: STOPSTORM Consortium Treatment Planning Benchmark." Radiotherapy and Oncology 182 (May 2023): S788—S790. http://dx.doi.org/10.1016/s0167-8140(23)08767-4.

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9

Cappelli, Barbara, Francoise Bernaudin, Annalisa Ruggeri, et al. "Hematopoietic Stem Cell Transplantation from HLA Identical Sibling Forsickle Cell Disease an International Survey on Behalf of Eurocord-Monacord, EBMT Paediatric Disease Working Party and CIBMTR." Blood 126, no. 23 (2015): 541. http://dx.doi.org/10.1182/blood.v126.23.541.541.

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Abstract Introduction: Hematopoietic stem cell transplantation (HSCT) is, to date, the only curative therapy for sickle cell disease (SCD). However, HSCT is offered to relatively few patients with SCD for a number of reasons including lack of a suitable HLA-matched donor, lack of consensus on indications for HSCT, the potential for trading one chronic condition (i.e., SCD) for another, such as chronic graft-versus-host disease (GVHD), and the mortality associated with the procedure. To-date, most HSCTs for SCD have utilized matched siblings as donors and are performed in children and adolescen

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10

Mali, Raghuveer, Holly Rene Martin, Baskar Ramdas, et al. "Novel Functional Roles for Ten-Eleven-Translocation 2 (Tet2) in Normal and Leukemic Growth of Mast Cells." Blood 126, no. 23 (2015): 775. http://dx.doi.org/10.1182/blood.v126.23.775.775.

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Abstract KIT receptor signaling plays an important role in mast cell development. Gain-of-function mutations in KIT receptor have been identified in human diseases including gastrointestinal stromal tumors (GIST), systemic mastocytosis (SM) and acute myeloid leukemia (AML). Although KIT mutations found in GIST are sensitive to imatinib, KIT mutation (KITD816V) found in 90% of SM patients is imatinib-resistant and currently no therapies are available to treat the human diseases associated with this mutation. Our recent studies have identified Ten-Eleven-Translocation 2 (TET2) mutations in ~23%

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Books on the topic "324.6/23/0941"

1

D, Gordon Ann, and Collier-Thomas Bettye, eds. African American women and the vote, 1837-1965. University of Massachusetts Press, 1997.

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2

Suffrage Reader: Charting Directions in British Suffrage History. Bloomsbury Publishing Plc, 2000.

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(Editor), Claire Eustance, Joan Ryan (Editor), and Laura Ugolini (Editor), eds. A Suffrage Reader: Charting Directions in British Suffrage History. Continuum International Publishing Group, 2000.

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Feminism and Democracy: Women's Suffrage and Reform Politics in Britain, 19001918. Cambridge University Press, 2003.

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Feminism and democracy: Women's suffrage and reform politics in Britain, 1900-1918. Cambridge University Press, 1986.

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Woman's Voice, Woman's Place: Lucy Stone and the Birth of the Woman's Rights Movement. Praeger Publishers, 2003.

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Conference papers on the topic "324.6/23/0941"

1

Drenberg, Christina D., Brian Fermanski, Steven Zatechka, et al. "Abstract C170: GDC-0941 inhibits cytarabine-induced PI3K/AKT signaling and promotes synergistic activity in acute myeloid leukemia." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Oct 19-23, 2013; Boston, MA. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1535-7163.targ-13-c170.

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