Academic literature on the topic '346.546.1 (043.2)'

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Journal articles on the topic "346.546.1 (043.2)"

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Marincowitz, Carl, Omar Bouamra, Tim Coates, et al. "1427 The effect of the COVID-19 pandemic on major trauma presentations and patient outcomes in English hospitals." Emergency Medicine Journal 39, no. 12 (2022): A960.2—A964. http://dx.doi.org/10.1136/emermed-2022-rcem2.2.

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Aims, Objectives and BackgroundThere is evidence that COVID-19 ‘lockdowns’ may have contributed to increased non-accidental injury, domestic violence and self-harm related to deteriorating mental health. Internationally, there is also evidence that the diversion of health care resources may led to worse outcomes for patients presenting with major trauma. There has been no previous national evaluation of ‘lockdown’ measures impact on the characteristics, treatment pathways and outcomes of trauma patients in EnglandWe aimed to assess the impact of successive lockdowns on the volume, demographics
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Bowmaker, Graham A., Effendy, Robert D. Hart, John D. Kildea, and Allan H. White. "Lewis-Base Adducts of Group 11 Metal(I) Compounds. LXXIII Synthesis, Spectroscopy and Structural Systematics of New 1 : 1 'Cubane' Tetramers of Copper(I) and Silver(I) Halides with Triphenylarsine." Australian Journal of Chemistry 50, no. 6 (1997): 653. http://dx.doi.org/10.1071/c96039.

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Syntheses and room-temperature single-crystal X-ray structural characterization of a number of 1 : 1 ‘cube tetramer’ adducts of copper(I) and silver(I) halides, MX, with triphenylarsine, AsPh3, are recorded, being [XM(AsPh3)]4. The CuBr adduct, obtained unsolvated from toluene, orthorhombic Pbcn, a 17·844(5), b 20·778(8), c 18·430(4) Å, Z = 4 tetramers, conventional R on |F| 0·058 for No 1309 independent ‘observed’ reflctions (I > 3σ(I)), is isomorphous with previously recorded [ClAg(PPh3)]4, the tetramer having crystallographically imposed 2 symmetry. The CuI adduct, previously recorded as
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Manpoong, Chowlani, and S. K. Tripathi. "Soil properties under different land use systems of Mizoram, North East India." Journal of Applied and Natural Science 11, no. 1 (2019): 121–25. http://dx.doi.org/10.31018/jans.v11i1.1999.

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Changes in land use and improper soil management have led to severe land degradation around the globe through the modification in soil physicochemical and biological processes. This study aimed to assess the soil properties of different land use system types. Soil samples (0-15 cm depth) were collected from five land uses; Rubber Plantation (RP), Oil Palm Plantation (OPP), Bamboo Forest (BF), Fallow Land (FL) and Natural Forest (NF) and analyzed for bulk density, soil texture, soil pH, soil moisture, soil carbon, total nitrogen, ammonium, nitrate, soil microbial biomass carbon, soil respiratio
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Collette, Christopher, Amani M. Norling, Randall A. Walden, et al. "30 Hippocampal Internal Architecture Subfield Volumes Associated with Systematic Inflammatory Biomarkers in Multiple Sclerosis." Journal of the International Neuropsychological Society 29, s1 (2023): 546–47. http://dx.doi.org/10.1017/s1355617723007014.

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Objective:Multiple Sclerosis (MS) affects up to 500,000 adults in the United States, with cognitive impairment present in 45%-65% of people. Studies showed hippocampal atrophy in MS, but the underlying mechanisms remain unknown. Inflammation has been proposed to play a significant role, and associations between systemic inflammatory biomarkers and hippocampal atrophy have been shown in other neurological conditions. However, research exploring serum biomarker and volumetric associations in MS are lacking. Given that conventional imaging methods lack resolution for hippocampal internal architec
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Demetri, George D., Jason J. Luke, Antoine Hollebecque, et al. "First-in-human phase 1 study of ABBV-085, an antibody-drug conjugate (ADC) targeting LRRC15, in sarcomas and other advanced solid tumors." Journal of Clinical Oncology 37, no. 15_suppl (2019): 3004. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.3004.

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3004 Background: ABBV-085 is an ADC (conjugated to monomethyl auristatin E, drug:antibody ratio of 2:1) directed against leucine-rich repeat containing 15 (LRRC15), a type 1 transmembrane protein highly expressed on the surface of sarcomas and cancer-associated fibroblasts in stroma of many other cancers. ABBV-085 induced antitumor activity in both in vitro and xenograft models of sarcoma. This phase 1, first-in-human, 2-part study assessed the safety/tolerability of ABBV-085 in patients (pts) with advanced solid tumors (NCT02565758). Methods: Eligible pts (≥18 yr; advanced solid tumors) recei
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Qayyum, Waqar, Asma Naseem, Muhammad Nadeem, Sumaira Mushtaq, Rabia Tahir, and Qurra tul Ain. "Incidence and Outcomes of Renal Derangements in Covid-19 Patients of a Tertiary Care Hospital." Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University 21, no. 1 (2025): 235–39. https://doi.org/10.48036/apims.v21i1.1322.

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Objective: To assess the incidence and outcomes of acute kidney injury in patients diagnosed with Covid-19. Methodology: This cross-sectional study was carried out in the department of medicine, Shaikh Khalifa Bin Zayed Al Nahyan Hospital/CMH, Rawalakot, AJK, Pakistan from May 2021 to May 2023. Total 676 patients (ages ? 18 years) admitted with Covid-19 confirmed through polymerase chain reaction (PCR) having normal renal function tests (RFTs) at admission were included in the study. RFTs were done during admission and patients were followed up for outcome. The kidney disease improving global
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Pekov, Igor V., Natalia V. Zubkova, Vasiliy O. Yapaskurt, et al. "New arsenate minerals from the Arsenatnaya fumarole, Tolbachik volcano, Kamchatka, Russia. VI. Melanarsite, K3Cu7Fe3+O4(AsO4)4." Mineralogical Magazine 80, no. 5 (2016): 855–67. http://dx.doi.org/10.1180/minmag.2016.080.027.

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AbstractThe new mineral melanarsite, K3Cu7Fe3+O4(AsO4)4, was found in the sublimates of the Arsenatnaya fumarole at the Second scoria cone of the Northern Breakthrough of the Great Tolbachik Fissure Eruption, Tolbachik volcano, Kamchatka Peninsula, Russia. It is associated with dmisokolovite, shchurovskyite, bradaczekite, hematite, tenorite, aphthitalite, johillerite, arsmirandite, As-bearing orthoclase, hatertite, pharmazincite, etc. Melanarsite occurs as tabular to prismatic crystals up to 0.4 mm, separate or combined in clusters up to 1 mm across or in interrupted crusts up to 0.02 cm × 1 c
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Lucas, C., S. Rodriguez, R. Jean, et al. "AB0034 EARLY IMMUNIZATION AGAINST TREATMENT IS ASSOCIATED TO POOR CLINICAL RESPONSE AT 6 MONTHS AND LOW NUMBER OF TRANSITIONAL B CELLS AT BASELINE IN RHEUMATOID ARTHRITIS PATIENTS TREATED BY ADALIMUMAB." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1319.1–1320. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3938.

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Background:Circulating anti-drug antibodies (ADAs) are detectable approximatively in 33% of adalimumab treated rheumatoid arthritis (RA) patients, often within the first 6 months of therapy1-2. Classically, circulating ADAs associate with their specific drugs to form immune complexes, increasing drug clearance, and by this mechanism reducing therapeutic effect3. B cell involvement leading to ADAs production is not yet well established.Objectives:To study early ADAs formation according to clinical response to an adalimumab therapy in RA patients and the relationship between ADAs and circulating
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Ross, M. G., D. J. Sherman, M. G. Ervin, L. Day, and J. Humme. "Fetal swallowing: response to systemic hypotension." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 258, no. 1 (1990): R130—R134. http://dx.doi.org/10.1152/ajpregu.1990.258.1.r130.

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The fetal swallowing and endocrine responses to systemic hypotension were studied in five chronically instrumented ovine fetuses (125 +/- 2 days). Fetuses were prepared with bipolar electrodes inserted in the thyrohyoid muscle, nuchal esophagus, and thoracic esophagus, a flow probe surrounding the thoracic esophagus, and arterial and venous catheters. In response to an intravenous infusion of sodium nitroprusside, fetal mean arterial blood pressure decreased from 50.8 +/- 3.6 to 41.7 +/- 3.8 mmHg. Fetal plasma renin activity (5.0 +/- 1.4-25.1 +/- 10.3 ng.ml-1.h-1) and arginine vasopressin (5.6
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Borad, Mitesh J., Shantan G. Reddy, Nathan Bahary, et al. "Randomized Phase II Trial of Gemcitabine Plus TH-302 Versus Gemcitabine in Patients With Advanced Pancreatic Cancer." Journal of Clinical Oncology 33, no. 13 (2015): 1475–81. http://dx.doi.org/10.1200/jco.2014.55.7504.

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Purpose TH-302 is an investigational hypoxia-activated prodrug that releases the DNA alkylator bromo-isophosphoramide mustard in hypoxic settings. This phase II study (NCT01144455) evaluated gemcitabine plus TH-302 in patients with previously untreated, locally advanced or metastatic pancreatic cancer. Patients and Methods Patients were randomly assigned 1:1:1 to gemcitabine (1,000 mg/m2), gemcitabine plus TH-302 240 mg/m2 (G+T240), or gemcitabine plus TH-302 340 mg/m2 (G+T340). Randomized crossover after progression on gemcitabine was allowed. The primary end point was progression-free surviv
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Conference papers on the topic "346.546.1 (043.2)"

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Barbosa, Lucas Mendes. "Dienogeste versus dispositivo intrauterino hormonal para dismenorreia em mulheres com adenomiose: uma revisão sistemática e meta-análise de ensaios clínicos randomizados." In Resumos do 48º Congresso de ginecologia e obstetrícia. Zeppelini Editorial e Comunicação, 2024. https://doi.org/10.5327/jbg-2965-3711-2024134s1047.

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Objetivo: Comparar a eficácia do dienogeste com a do dispositivo intrauterino hormonal (DIU hormonal) para dismenorreia em mulheres com adenomiose. Fontes de dados: Realizamos uma busca sistemática nas bases de dados United States National Library of Medicine (PubMed), Embase e Cochrane Library por ensaios clínicos randomizados. A busca teve início no dia 06/03/2024, e a meta-análise foi concluída no dia 24/03/2024. O artigo foi registrado prospectivamente no PROSPERO com identificador CRD42024521221. Seleção de estudos: Foram selecionados 596 estudos para triagem. Desses, cinco foram lidos in
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Reports on the topic "346.546.1 (043.2)"

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Newman-Toker, David E., Susan M. Peterson, Shervin Badihian, et al. Diagnostic Errors in the Emergency Department: A Systematic Review. Agency for Healthcare Research and Quality (AHRQ), 2022. http://dx.doi.org/10.23970/ahrqepccer258.

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Objectives. Diagnostic errors are a known patient safety concern across all clinical settings, including the emergency department (ED). We conducted a systematic review to determine the most frequent diseases and clinical presentations associated with diagnostic errors (and resulting harms) in the ED, measure error and harm frequency, as well as assess causal factors. Methods. We searched PubMed®, Cumulative Index to Nursing and Allied Health Literature (CINAHL®), and Embase® from January 2000 through September 2021. We included research studies and targeted grey literature reporting diagnosti
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