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Relevant bibliographies by topics / 4,5-dihydro-1H-pyrazoles

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Journal articles

Academic literature on the topic '4,5-dihydro-1H-pyrazoles'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Journal articles on the topic "4,5-dihydro-1H-pyrazoles"

1

Zhu, Yu, Jun-Jie Hong, Yun-Bin Zhou, Yu-Wei Xiao, Min Lin, and Zhuang-Ping Zhan. "Selective synthesis of 4-(sulfonyl)-methyl-1H-pyrazoles and (E)-4,5-dihydro-1H-pyrazoles from N-allenic sulfonylhydrazones." Org. Biomol. Chem. 12, no. 23 (2014): 3797–801. http://dx.doi.org/10.1039/c4ob00550c.

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2

Kukharev, B. F., V. K. Stankevich, N. A. Lobanova, G. R. Klimenko, and E. Kh Sadykov. "N-(2-Vinyloxyethyl)-4,5-dihydro-1H-pyrazoles." Russian Journal of Organic Chemistry 43, no. 4 (2007): 628–29. http://dx.doi.org/10.1134/s1070428007040264.

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3

Chovatia, P. T., J. D. Akabari, P. K. Kachhadia, P. D. Zalavadia, and H. S. Joshi. "Synthesis and selective antitubercular and antimicrobial inhibitory activity of 1-acetyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazole derivatives." Journal of the Serbian Chemical Society 71, no. 7 (2006): 713–20. http://dx.doi.org/10.2298/jsc0607713c.

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The new compounds 1-aryl-3-{1-phenyl-3-[p (methylthio)phenyl]pyrazol-4-yl}-2-propen-1-ones 2a?l were prepared by the condensation of 1-phenyl-3-[p (methylthio)phenyl]-4-formylpyrazole 1 with different aryl ketones. Compounds 2a?l in reaction with hydrazine hydrate yielded 3-aryl-5-{1-phenyl-3-[p-(methylthio)phenyl]pyrazol-4 yl}-4,5-dihydro-(1H)-pyrazoles 3a?l and in the presence of hydrazine hydrate in glacial acetic acid gave 1-acetyl-3-aryl 5-{1-phenyl-3-[p-(methylthio)phenyl]pyrazol-4-yl}-4,5 dihydro-(1H)-pyrazoles 4a?l. These compounds were tested in vitro for their antitubercular and anti

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4

Thirunarayanan, Ganesamoorthy, and K. Ravi. "Synthesis and Spectral Correlation Study of some 3-(3,4-dichlorophenyl)-5-(Substituted Phenyl)-4,5-dihydro-¹H-Pyrazole-1-yl-Ethanones." International Letters of Chemistry, Physics and Astronomy 19 (October 2013): 44–57. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.19.44.

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Some N-acetyl pyrazoles including 3-(3,4-dichlorophenyl)-5-(substituted phenyl)-4,5-dihydro-1H-pyrazole-1-yl-ethanones have been synthesised by solvent free cyclization cum acetylation of chalcones including substituted styryl 3,4-dichlorophenyl ketones using hydrazine hydrate and acetic anhydride in presence of catalytic amount of fly-ash: H2SO4 catalyst. The yield of these N-acetyl pyrazole derivatives are more than 75%. The synthesised N-acetyl pyrazoline derivatives were characterized by their physical constants and spectral data. The infrared spectral νC=N and C=O (cm-1) frequencies, NMR

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5

Chen, Yi-Hui, Hai-Tao Tang, Jia-Hao Zeng, Jun-Jia Chen, and Zhuang-Ping Zhan. "Synthesis of (E)-4,5-Dihydro-1H-Pyrazoles via Tandem Intermolecular Addition–Cyclization of N-Propargylic Sulfonylhydrazones." Synlett 28, no. 15 (2017): 2036–40. http://dx.doi.org/10.1055/s-0036-1588844.

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A new strategy for the synthesis of (E)-4-benzylidene-4,5-dihydro-1H-pyrazoles through tandem intermolecular addition–intramolecular cyclization of N-propargylic sulfonylhydrazones has been developed. In this study, we firstly report that N-propargylic sulfonylhydrazones react with electrophilic reagents to afford 4-substituted pyrazole derivatives.

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6

Altıntop, Mehlika Dilek. "Synthesis, In vitro and In silico Evaluation of a Series of Pyrazolines as New Anticholinesterase Agents." Letters in Drug Design & Discovery 17, no. 5 (2020): 574–84. http://dx.doi.org/10.2174/1570180816666190618111023.

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Background: Pyrazolines, electron-rich nitrogen carriers, are of great importance due to their potential applications for the treatment of many diseases including inflammation, infectious diseases and neurodegenerative disorders. Objectives: The purpose of this work was to synthesize new pyrazoline derivatives and evaluate their anticholinesterase effects. Methods: 1-Aryl-5-[4-(piperidin-1-yl)phenyl]-3-(3,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazoles (1-7) were synthesized via the treatment of 1-(3,4-dimethoxyphenyl)-3-[4-(piperidin-1-yl)phenyl]prop-2- en-1-one with arylhydrazine hydrochloride d

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7

Kukharev, B. F., V. K. Stankevich, N. A. Lobanova, V. G. Chernova, E. Kh Sadykov, and V. A. Apkhanov. "Reactions of vinyl 2,3-epoxypropyl ethers with 4,5-dihydro-1H-pyrazoles." Russian Journal of Organic Chemistry 42, no. 10 (2006): 1498–500. http://dx.doi.org/10.1134/s1070428006100174.

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8

Burde, P. C., and A. M. Rahatgaonkar. "Facile Synthesis and Biological Evaluation of Cyclopropyl-Pyrazole Hybrids in [bmim][PF6]-Water Biphasic System as Antifungal Agents." Asian Journal of Organic & Medicinal Chemistry 4, no. 3 (2019): 152–58. http://dx.doi.org/10.14233/ajomc.2019.ajomc-p192.

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3-Cyclopropyl-5-(4-substituted)-1-phenyl-4,5-dihydro-1H-pyrazoles derived from corresponding chalcones were synthesized and evaluated for their biological activities. A convenient synthesis of a library of these compounds in 1-butyl-3-methylimidazolium hexafluorophosphate-water biphasic system at ambient temperature has been accomplished. The ionic liquid, [bmim][PF6] and water which are immiscible, has been easily recycled and reused after separation of the products without any noticeable diminution in its activity.

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9

Venkata Narsimha Reddy, Chintalapani, Eligeti Rajanarendar, and Ananthula Krishnamurthy. "Synthesis of 3-methyl-1,5-diphenyl-7-aryl-7,8-dihydro-6H-pyrazolo[4,5-b]azepines." Collection of Czechoslovak Chemical Communications 55, no. 4 (1990): 1055–58. http://dx.doi.org/10.1135/cccc19901055.

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3,5-Dimethyl-4-nitro-1-phenylpyrazole (I) on treatment with chalcones II under phase transfer conditions gives the Michael adducts, 3-methyl-4-nitro-1-phenyl-5-(2-aryl-4-phenyl-4-oxo-1-butyl)pyrazoles (III). The Michale adducts on cycloreduction with stannous chloride-hydrochloric acid furnish 3-methyl-1,5-diphenyl-7-aryl-7,8-dihydro-6H-pyrazolo[4,5-b]azepines (IV). IR, 1H NMR, 13C NMR and mass spectra support the structures of III and IV.

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10

Ramos, Daniela Fernandes, Gabriela Fiss, Clarissa Piccinin Frizzo, et al. "Activity of 4,5-dihydro-1H-pyrazoles against Mycobacterium tuberculosis and nontuberculous mycobacteria." International Journal of Antimicrobial Agents 43, no. 5 (2014): 481–83. http://dx.doi.org/10.1016/j.ijantimicag.2014.02.004.

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