Relevant bibliographies by topics / 4-b]-Pyridine; 1

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Academic literature on the topic '4-b]-Pyridine; 1'

Author: Grafiati
Published: 7 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "4-b]-Pyridine; 1"

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Grinberga, S., A. Krauze, L. Krasnova, and G. Duburs. "Synthesis of 4-Benzo[1,3]Dioxol-5-Ylthieno-[2,3-b]Pyridines." Latvian Journal of Chemistry 51, no. 1-2 (2012): 143–48. http://dx.doi.org/10.2478/v10161-012-0002-2.

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Synthesis of 4-Benzo[1,3]Dioxol-5-Ylthieno-[2,3-b]Pyridines 4,7-Dihydrothieno[2,3-b]pyridine 4 and thieno[2,3-b]pyridine 6 were obtained by Thorpe-Ziegler cyclization. Mn(OAc)3/acetic acid system had been used for oxidation of 1,4-dihydropyridine 3 to pyridine derivative 5. 6-Carbamoylmethylsulfanyl-1,4-dihydropyridine 3 was prepared by al-kylation of piperidinium 1,4-dihydropyridine-2-thiolate 1 with iodoacet-amide.
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Fathi, Anwar Abdulghani, Yassir Shakeeb Al Jawaheri, and Shaimaa Samir Ismaee. "Synthesis of some new substituted imines from aldehydes and ketones derived from quinolinic acid." Ecletica Quimica 48, no. 2 (2023): 49–65. http://dx.doi.org/10.26850/1678-4618eqj.v48.2.2023.p49-65.

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In this paper, some substituted imines compounds have been prepared from quinolinic acid as a starting material. Firstly, the quinolinic acid was treated with acetic anhydride and acetic acid to form furo[3,4-b]pyridine-5,7-dione (1); the resulting compound was heated with urea to form 5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione (2). After that, it was treated with potassium hydroxide to give potassium 5,7-dioxo-5,7-dihydropyrrolo[3,4-b]pyridin-6-dione, which was directly and easily converted to 6-(2-([1,1'-biphenyl]-4-yl)-2-oxoethyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione (3) by the reaction wit
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Norman, Rebecca E., Michael V. Perkins, Andris J. Liepa, and Craig L. Francis. "N,N-Dialkyl-N′-Chlorosulfonyl Chloroformamidines in Heterocyclic Synthesis. Part X. The First Pyrazolo[1,5-b][1,2,4,6]thiatriazine Derivatives and their Unusual Reactions with Acylating Agents." Australian Journal of Chemistry 66, no. 11 (2013): 1323. http://dx.doi.org/10.1071/ch13282.

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N,N-dialkyl-N′-chlorosulfonyl chloroformamidines 1 underwent a regioselective reaction with 3-aminopyrazoles 2 to produce pyrazolo[1,5-b][1,2,4,6]thiatriazines 3, representatives of a new ring system. Attempted N-acylation of compounds 3 with acetic anhydride (or chloride) and benzoyl chloride in pyridine, only afforded 5-(pyridin-4-yl)-pyrazolo[1,5-b][1,2,4,6]thiatriazine derivatives 11. The analogous reaction with pyridazine led to the corresponding pyridazin-4-yl derivative.
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Gad-Elkareem, Mohamed A. M., Azza M. Abdel-Fattah, and Mohamed A. A. Elneairy. "Pyrazolo[3,4-b]pyridine in heterocyclic synthesis: synthesis of new pyrazolo[3,4-b]pyridines, imidazo[1',2':1,5]pyrazolo[3,4-b]pyridines, and pyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidines." Canadian Journal of Chemistry 85, no. 9 (2007): 592–99. http://dx.doi.org/10.1139/v07-089.

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Pyrazolo[3,4-b]pyridine derivatives 7 and 9 were synthesized via the reaction of 3-amino-1H-pyrazolo-[3,4-b]pyridine derivative 2 with ω-bromoacetophenones. Reaction of 7 and 9 with Ac2O afforded the imidazo[1',2':1,5]py razolo[3,4-b]pyridine derivative 8 and pyrazolo[3,4-b]pyridine derivative 10, respectively. Reaction of 2 with chloroacetonitrile followed by DMF-DMA gave imidazo[1',2':1,5]pyrazolo[3,4-b]pyridines 4 and 5, respectively. Acetyl acetone and 1,1-dicyano-2,2-dimethylthioethene were reacted with 2 to afford the pyrido[2',3':3,4]pyrazolo-[1,5-a]-pyrimidines 11 and 14, respectively.
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Abbas, Ashraf A., Mohamed A. A. Elneairy та Yehia N. Mabkhot. "Versatile Starting Materials for Novel 1,ω-bis(pyridin-4-ylphenoxy)alkanes, and their Corresponding bis(thieno[2,3-b]pyridin-4-ylphenoxy) derivatives". Journal of Chemical Research 2001, № 4 (2001): 124–26. http://dx.doi.org/10.3184/030823401103169388.

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A synthesis is described, starting from p-hydroxybenzaldehyde, of some new bis(activated styrene) derivatives, and their conversion into novel bis(pyridin-4-yl) ethers and bis(thieno[2,3- b]pyridine) derivatives.
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Yakovenko, G. G., and M. V. Vovk. "Convenient approaches to the synthesis of 6-amino- and 6-oxoimidazo[4,5-b]pyrazolo[3,4-e]pyridines." Journal of Organic and Pharmaceutical Chemistry 19, no. 1(73) (2021): 10–15. http://dx.doi.org/10.24959/ophcj.21.224583.

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Aim. To develop convenient approaches to the synthesis of 6-amino- and 6-oxoimidazo[4,5-b]pyrazolo[3,4-e]pyridines as promising biologically active scaffolds.Results and discussion. It has been found that cyclocondensation of N-Boc-4-aminopyrazole-5-carbaldehydes with creatinine can be used as an effective method for obtaining 6-aminoimidazo[4,5-b]pyrazolo[3,4-e]pyridines previously unknown. For the synthesis of their 6-oxoanalogs, the reaction of 5-aminopyrazolo[4,3-b]pyridine-6-carboxylic acids used in a modifed Curtius rearrangement with diphenylphosphorylazide was successful. This method was
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Malik, Siddharth, and Tulasi Yadati. "A Comprehensive Review on IRAK-4 Inhibitors." International Journal of Drug Design and Discovery 5, no. 4 (2025): 1401–4. https://doi.org/10.37285/ijddd.5.4.3.

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Interleukin-1 receptor-associated kinases (IRAKs) are key component in the signal transduction utilized by interleukin-1 receptor (IL-1R), interleukin-18 receptor (IL-18R), and Toll-like receptors (TLRs). It plays a pivotal role in alleviating chronic inflammatory and autoimmune disorders. IRAK-4 is also known as “master IRAK” due its role in IL-1R/TLR signaling. Various potent series with IRAK4 inhibitory activity have been reported., including Thiazole and Pyridine Amides, Aminobenzimidazoles, Imidazo[1,2-a]pyridines and Imidazo[1,2-b]pyridazine and Indazole inhibitors. Here, we have present
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Nasir, Hussain, Ram Dangi Raja, Kumar Sain Devendra, and L. Talesara Ganpat. "Convenient synthesis of 1-N, 7-N-bisethoxyphthalimido-4-(3,5-dimethyl-4- substitutedphenyl-4, 7-dihydro-1H-dipyrazolo[3,4-b;4' ,3' -e ]pyridin-8-yl)phenylamine." Journal of Indian Chemical Society Vol. 88, Jul 2011 (2011): 1021–24. https://doi.org/10.5281/zenodo.5785141.

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Synthetic Organic Chemistry Research Laboratory, Department of Chemistry, M. L. Sukhadia University, Udaipur-313 001, Rajasthan, India <em>E-mail </em>: glntalesara@yahoo.com <em>Manuscript received 22 March 2010, revised 05 October 2010, accepted 30 December 2010</em> In the three component one pot synthesis 5-methyl-2,4-dihydro-3H-pyrazole-3-one reacted with substituted aldehydes and p-phenylenediamine to produce 4-{3,5-dimethyl-4-(substitutedphenyl)-4, 7-dihydro-1H-diprazolo[3,4-b;4<em>&#39;</em> ,3<em>&#39;</em>e] pyridin-8-yl}phenylamine (4a-e). Condensation of (4a-e) with two mole of bro
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Ryzhkova, Yuliya E., Fedor V. Ryzhkov, Oleg I. Maslov, and Michail N. Elinson. "2,4-Diamino-5-(5-hydroxy-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-5H-chromeno[2,3-b]pyridine-3-carbonitrile." Molbank 2023, no. 1 (2023): M1541. http://dx.doi.org/10.3390/m1541.

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5H-Chromeno[2,3-b]pyridines are important compounds with industrial, biological, and medicinal properties. In this short note, the multicomponent reaction of salicylaldehyde, malononitrile dimer, and 2-phenyl-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one in dimethyl sulfoxide at ambient temperature was investigated to give 2,4-diamino-5-(5-hydroxy-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-5H-chromeno[2,3-b]pyridine-3-carbonitrile with good yield. The structure of the previously unknown chromeno[2,3-b]pyridine derivative was confirmed by elemental analysis, mass, nuclear magnetic resonan
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Selig, Roland, Dieter Schollmeyer, Wolfgang Albrecht, and Stefan Laufer. "4-Chloro-1-(4-methylphenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine." Acta Crystallographica Section E Structure Reports Online 65, no. 12 (2009): o3018. http://dx.doi.org/10.1107/s1600536809044559.

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Dissertations / Theses on the topic "4-b]-Pyridine; 1"

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Hajbi, Youssef. "Application de la réaction de Diels-Alder à demande électronique inverse à la synthèse de nouveaux composés oxygénés et azotés à visée thérapeutique." Phd thesis, Université d'Orléans, 2007. http://tel.archives-ouvertes.fr/tel-00151105.

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Cette thèse s'inscrit dans une volonté de développer de nouvelles architectures hétéroaromatiques susceptible de montrer un potentiel thérapeutique. Pour cela la synthèse de dihydrofuro[2,3-b]pyridines et dihydropyrano[2,3-b]pyridines hautement et diversement fonctionnalisées est apparue particulièrement intéressante notamment en vue de l'obtention de nouveaux analogues sérotoninergiques. L'accès à ces nouveaux squelettes a été réalisé via une réaction intramoléculaire de Diels-Alder à demande électronique inverse avec des 1,2,4-triazines. <br /><br />Pour ce faire, des 3-méthylsulfanyl-1,2,4-
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Meyer, Holger. "Pyrido[3,2-b]indol-4-yl-amine, [1]Benzofuro[3,2-b]pyridin-4-yl-amine und [1]Benzothieno[3,2-b]pyridin-4-yl-amine : Darstellung von Antimalariamitteln /." [S.l. : s.n.], 2003. http://www.gbv.de/dms/bs/toc/374105367.pdf.

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Kumari, Archana. "Synthesis of Pyrazolo [3, 4-b] pyridine by Knovengel Condensation." Thesis, 2009. http://ethesis.nitrkl.ac.in/190/1/.

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We have successfully prepared some novel pyrazole derivatives. More interestingly, a new pyrazolopyridine derivative i.e. Ethyl 6-amino-1,3-diphenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate was prepared by the knovengel condensation of 5-amino-pyrazole-4-carbaldehyde and ethylcyanoacetate.
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Books on the topic "4-b]-Pyridine; 1"

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Decker-Burgard, Sabine. Antimutagene Effekte verschiedener Apfeisorten, Orangen- und Grapefruitchargen im Salmonella/Reversions-Test gegenüber den Mutagenen 2-Amino-3-methylimidazo (4, 5-f)chinolin (IQ), 2-Amino-1-methyl-6-phenylimidazo (4, 5-b)pyridin (PhIP), Benzo(a)pyren, 2-Nitrofluoren, 2,4,7-Trinitro-9-fluorenon, Natriumazid, [beta]-Propiolacton und Captafol. 1995.

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Book chapters on the topic "4-b]-Pyridine; 1"

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Taber, Douglass. "Adventures in Alkaloid Synthesis: ( + )-α-Kainic Acid (Jung), 223AB (Ma), Pumiliotoxin 251F (Jamison), Spirotryprostatin B (Trost), (-)-Drupacine (Stoltz)." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0058.

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Enantiomerically-pure natural amino acids can serve as starting materials for alkaloid synthesis. In his synthesis (J. Org. Chem. 2007, 72, 10114) of (-)-α-kainic acid 3, Kyung Woon Jung of the University of Southern California prepared the diazo sulfone 1 from (L)-glutamic acid. Rh-mediated intramolecular C-H insertion proceeded with the predicted high diastereoselectivity, to give the lactam 2, containing seven of the ten carbon atoms and two of the three stereogenic centers of (-)-α-kainic acid 3. The absolute configuration of the nitrogen ring system(s) can also be established by chiral ca
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Taber, Douglass. "Intermolecular and Intramolecular Diels-Alder Reactions: (-)-Oseltamivir (Fukuyama), Platensimycin (Yamamoto) and 11,12-Diacetoxydrimane (Jacobsen)." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0078.

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Powerful methods for catalytic, enantioselective intermolecular Diels-Alder reactions have been developed. Ben L. Feringa and Gerard Roelfes of the University of Groningen have shown (Organic Lett. 2007, 9, 3647) that a catalyst prepared by combining salmon testes DNA with a Cu complex directed the absolute sense of the addition of 1 to cyclopentadiene 2 . Mukund P. Sibi of North Dakota State University has reported (J. Am. Chem. Soc . 2007, 129 , 395) related work with achiral pyrazolidinone dienophiles and chiral Cu catalysts. Tohru Fukuyama of the University of Tokyo found (Angew. Chem. Int
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Seibel, Zara M., and Tristan H. Lambert. "Construction of Alkylated Stereocenters." In Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0035.

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Hirohisa Ohmiya and Masaya Sawamura at Hokkaido University reported (Angew. Chem. Int. Ed. 2013, 52, 5350) the copper-catalyzed, γ-selective allylation of terminal alkyne 1 to produce the chiral skipped enyne 3 with high ee. A method to synthe­size asymmetric skipped diene 6 via copper-catalyzed allylic allylation of diene 4 was developed (Chem. Commun. 2013, 49, 3309) by Ben L. Feringa at the University of Groningen. Prof. Feringa also disclosed (J. Am. Chem. Soc. 2013, 135, 2140) the regi­oselective and enantioselective allyl–allyl coupling of bromide 7 with allyl Grignard under Cu catalysis
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Taber, Douglass F. "Alkaloid Synthesis: (−)-L-Batzellaside A (Toyooka), Limazepine A (Zemribo), (+)-Febrifugine (Pansare), Amathaspiramide F (Tambar), Allomatrine (Brown), Lyconadine C (Waters), Tabersonine (Andrade)." In Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0057.

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Naoki Toyooka of the University of Toyama prepared (Eur. J. Org. Chem. 2013, 2841) the lactam 1 from commercial tri-O-benzyl-D-glucal. Reduction with Dibal followed by coupling of the intermediate with allyltrimethylsilane delivered the piper­idine 2, that was carried on to (−)-L-batzellaside A 3. Ronalds Zemribo of the Latvian Institute of Organic Synthesis effected (Org. Lett. 2013, 15, 4406) Ireland–Claisen rearrangement of the lactone 4 to give the pyrroli­dine 5 with high geometric control. This was readily converted to limazepine E 6. Sunil V. Pansare of Memorial University used (Synthes
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Lambert, Tristan H. "New Methods for C–N Ring Construction." In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0055.

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The reduction of pyridines offers an attractive approach to piperidine synthesis, and now Toshimichi Ohmura and Michinori Suginome of Kyoto University have developed (J. Am. Chem. Soc. 2012, 134, 3699) a rhodium-catalyzed hydroboration of pyridines, including the reaction of 1 to produce 3. Timothy J. Donohoe at the University of Oxford has found (Org. Lett. 2011, 13, 2074) that pyridinium silanes 4 undergo intramolecular hydride transfer by treatment with TBAF to produce dihydropyridones (e.g., 5) with good diastereoselectivity. Enantioselective amination of allylic alcohols has proven challe
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Fuller, Stephen J., and James S. Wiley. "Anaemias resulting from defective maturation of red cells." In Oxford Textbook of Medicine, edited by Chris Hatton and Deborah Hay. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0538.

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Defective maturation of red cells leads to premature destruction of nucleated red cell precursors before they leave the haematopoietic bone marrow, which results in expansion of the marrow, haemolytic jaundice, peripheral signs of increased erythroid turnover on blood films, and (in long-standing disorders) iron overload due to enhanced absorption. Causes of ineffective erythropoiesis include (1) inhibition of erythroid DNA synthesis (e.g. megaloblastic anaemias (vitamin B<sub>12</sub> or folate deficiency), drugs blocking DNA synthesis); (2) clonal disorders of erythropoiesis (e.g. refractory
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Lambert, Tristan H. "Reactions of Alkenes." In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0031.

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Paul J. Chirik at Princeton University reported (Science 2012, 335, 567) an iron catalyst that hydrosilylates alkenes with anti-Markovnikov selectivity, as in the conversion of 1 to 2. A regioselective hydrocarbamoylation of terminal alkenes was developed (Chem. Lett. 2012, 41, 298) by Yoshiaki Nakao at Kyoto University and Tamejiro Hiyama at Chuo University, which allowed for the chemoselective conversion of diene 3 to amide 4. Gojko Lalic at the University of Washington reported (J. Am. Chem. Soc. 2012, 134, 6571) the conversion of terminal alkenes to tertiary amines, such as 5 to 6, with an
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Conference papers on the topic "4-b]-Pyridine; 1"

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Marbello, O. D., A. G. Pelosi, L. H. Z. Cocca, et al. "Analysis of the nonlinear optical response in Imidazo[4,5-b]Pyridine derivatives." In Latin America Optics and Photonics Conference. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/laop.2022.w4a.1.

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In this work, the linear and nonlinear optical properties of three Imidazo[4-5,b]pyridine derivatives were investigated The results show an increase in the fluorescence quantum efficiency and 2PA cross-section due to substituent groups.
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Yao-Borengasser, Aiwei, Lora J. Rogers, and Susan A. Kadlubar. "Abstract 5303: Uptake and Efflux of 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (PhIP) in human adipocytes." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-5303.

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Soares, Júlio César, Joana Ribeiro, Camilo Henrique Lima, Gisele Portapilla, Sérgio de Albuquerque, and Luiza Dias. "New 1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine derivatives with potent antichagasic activitys." In 4th International Electronic Conference on Medicinal Chemistry. MDPI, 2018. http://dx.doi.org/10.3390/ecmc-4-05610.

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Choudhary, Shambhunath, Shilpa Sood, Kusum Rathore, and Hwa-Chain Robert Wang. "Abstract 5467: Green tea catechin intervention of human breast cell carcinogenesis chronically induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-5467.

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