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Relevant bibliographies by topics / 5-(chloromethyl)-3-(4H-chromen-3-yl)-1

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Academic literature on the topic '5-(chloromethyl)-3-(4H-chromen-3-yl)-1'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "5-(chloromethyl)-3-(4H-chromen-3-yl)-1"

1

Chunduru, Srinivasa Rao, Venkata Ramana Reddyy Ch., Jyotsna C., and S. Sait Shakil. "Synthesis of 3-[5-(morpholinomethyl/piperidinomethyl/pyrrolidinemethyl)-1 ,2 ,4- oxadiazol-3-yl]-4H-chromones." Journal of Indian Chemical Society Vol. 90, Sep 2013 (2013): 1461–66. https://doi.org/10.5281/zenodo.5790902.

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Department of Chemistry, JNTU, Kukatpally, Hyderabad-500 085, India Dr. Reddy Laboratories, Bachupally, Hyderabad-500 090, India <em>E-mail </em>: chemistrycsr@gmail.com <em>Manuscript received online 04 November 2012, revised 05 December 2012, accepted 30 December 2012</em> 5-(Chloromethyl)-3-(4<em>H</em>-chromen-3-yl)-1,2,4-oxadiazole (1a-e) react with pyrrolidine (6) to give 3-(4<em>H</em>-chromen-3-yl)-5-(pyrrolidin-1-ylmethyl)-1,2,4-oxadiazole (7a-e), (1a-e) react with piperidine (4) to give 1-{[3-(4<em>H</em>-chromen-3-yl)- 1,2,4-oxadiazol-5-yl]methyl}piperidine (5a-e) and (1a-e) react w

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2

Gašparová, Renata, Pavol Koiš, Margita Lácová, Silvia Kováčová, and Andrej Boháč. "Synthesis, reactions and antineoplastic activity of 3-(2-oxo-2H-chromen-3-yl)-2-oxo-2H,5H-pyrano[3,2-c]chromene derivatives." Open Chemistry 11, no. 4 (2013): 502–13. http://dx.doi.org/10.2478/s11532-012-0184-1.

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AbstractThe key 3-(2-oxo-2H-chromen-3-yl)-2-oxo-2H,5H-pyrano[3,2-c]chromen-5-yl acetates 3 were synthesized in high yields by cyclocondensation of 4-oxo-4H-chromen-3-carbaldehydes 1 with coumarin-3-acetic acids 2 under mild conditions. The reaction pathway involves aldol condensation and subsequent intramolecular lactonization to afford 2-oxo-2H,5H-pyrano[3,2-c]chromene skeleton 3. Further treatment of acetates 3 with alcohols, water or nitrogen containing compounds led to 5-alkoxy-, 5-hydroxy- or 5-acylamino-2H,5H-pyrano[3,2-c]chromen-2-ones 4-6 via nucleophilic substitution of acetyloxy grou

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3

Razgulyaev, Vladislav I., Polina A. Nikitina, Tatiana Yu Koldaeva, Vladimir S. Miroshnikov, and Valery P. Perevalov. "SYNTHESIS OF 2-(3-CHROMENYL)-4-ETHOXYCARBONYL-1-(4-FLUOROBENZYL)-5-METHYLIMIDAZOLE 3-OXIDES." IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENIY KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA 60, no. 2 (2017): 17. http://dx.doi.org/10.6060/tcct.2017602.5435.

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In addition to our search for probable HIV-1 integrase inhibitors in the series of imidazole derivatives a possibility of preparation of 2-(3-chromenyl)substituted imidazole 3-oxides containing fluorobenzyl moiety in position 1 of imidazole ring as a potential pharmacophore was demonstrated. 4-ethoxycarbonyl-1-(4-fluorobenzyl)-5-methyl-2-(4-oxo-4H-chromen-3-yl)imidazole 3-oxide 4a and 4-ethoxycarbonyl-2-(6-hydroxy-4-oxo-4H-chromen-3-yl)-1-(4-fluorobenzyl)-5-methyli-midazole 3-oxide 4b were synthesized starting with fluorobenzylamine 1, ethyl 2-(hydroxyimino)-3-oxobutanoate 2 and 4-oxo-4H-chrom

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4

Niranjan, M.S. *. and Chaluvaraju K.C. "SYNTHESIS AND CHARACTERIZATION OF TWO NOVEL THIOFIBRATES DERIVED FROM 7-HYDROXY-4-METHYL-2H CHROMEN-2-ONE." Journal of Pharma Research 7, no. 8 (2018): 190–93. https://doi.org/10.5281/zenodo.1345716.

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<strong><em>ABSTRACT</em></strong> <strong><em>T</em></strong><em>wo novel thiofibrates bearing 1,3,4-oxadizole and 1,2,4-triazole are prepared from 7-hydroxy-4-methyl-</em><em>2H-chromen-2-one (1). The compound (1) is obtained by treating resorcinol with ethyl acetate in the presence of concentrated sulphuric acid. It is then treated with ethylchloroacetate to get ethyl((4-methyl-2-oxo-2H-chromen-7-yl)oxy)acetate (2). This on hydrogenolysis gives 2-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)acetohydrazide (3) which on further reaction with phenyl isothiocyanate in presence of sodium hydroxide gives

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5

Tank, Manishkumar Jinabhai, Navinkumar A. Kucha, Chirag G. Naik, Tina R. Barot, and G. M. Malik. "Adamantane-pyrido[2,3-d]pyrimidine Derivatives; Synthesis, Characterization and Investigation of Antimicrobial Study." Oriental Journal Of Chemistry 39, no. 2 (2023): 393–402. http://dx.doi.org/10.13005/ojc/390219.

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Target molecules based on Adamantane-pyrido[2,3-d]pyrimidine derivatives were prepared. Adamantane-pyrido[2,3-d]pyrimidine series using N-(hydroxyadamantan-1-yl)-5-(2,4-substitutedphenyl)-2-Methyl-4-Oxo-7-(2-oxo-2H-Chromen-3-yl)pyrido[2,3-d]Pyrimidine-3(4H)carboxamide (6a-j) was synthesized by reaction between 3-(2-chloroacetyl)-5-(2,4-substitutedphenyl)-2-Methyl-7-(2-Oxo-2H-Chromen-3-yl) pyrido[2,3-d]pyrimidin-4(3H)-one (5a-j) and 3-aminoadamantan-1-ol. These derivatives of Adamantane-pyrido[2,3-d]Pyrimidine were investigated in vitro for their biological characteristics against the strains w

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6

Albuquerque, Hélio M. T., Diana C. G. A. Pinto, and Artur M. S. Silva. "Microwave Irradiation: Alternative Heating Process for the Synthesis of Biologically Applicable Chromones, Quinolones, and Their Precursors." Molecules 26, no. 20 (2021): 6293. http://dx.doi.org/10.3390/molecules26206293.

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Microwave irradiation has become a popular heating technique in organic synthesis, mainly due to its short reaction times, solventless reactions, and, sometimes, higher yields. Additionally, microwave irradiation lowers energy consumption and, consequently, is ideal for optimization processes. Moreover, there is evidence that microwave irradiation can improve the regioselectivity and stereoselectivity aspects of vital importance in synthesizing bioactive compounds. These crucial features of microwave irradiation contribute to its inclusion in green chemistry procedures. Since 2003, the use of

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7

Ramina, Rajkumar Bhubon Singh, and Oinam U-wang. "Synthesis, Characterization and DNA Binding Studies of Some Hydrazide Derivatives Schiff Base Metal Complexes of Mn(II), Co(II/III), Ni(II), Cu(II) and Zn(II) Metal Ions." Asian Journal of Chemistry 33, no. 12 (2021): 3006–24. http://dx.doi.org/10.14233/ajchem.2021.23408.

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Eighteen metal complexes were synthesized by using four different Schiff base ligands, (1E)-1-((6-methyl-4-oxo-4H-chromen-3-yl)methylene)carbohydrazide (L1), 6-[2-(salicylidene)hydrazinyl]-N′-(salicylidene)nicotinohydrazide (HL2), 6-hydrazinyl-N′-(6-methyl- 4-oxo-4H-chromen-3-yl-methylene)nicotinohydrazide (HL3) and (E)-6-hydrazinyl-N′-(1-(2,3-dihydro- 1,3-dioxo-1H-inden-2-yl)-ethylidene)pyridine-3-carbohydrazide (L4). Characterization of the metal complexes were carried out by using various physico-chemical techniques. Complexes 1, 3, 4, 6, 11, 14, 15, 16, 17 and 18 have been found octahedral

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8

Asyakina, Lyudmila, Stanislav Sukhikh, Svetlana Ivanova, et al. "Determination of the Qualitative Composition of Biologically-Active Substances of Extracts of In Vitro Callus, Cell Suspension, and Root Cultures of the Medicinal Plant Rhodiola rosea." Biomolecules 11, no. 3 (2021): 365. http://dx.doi.org/10.3390/biom11030365.

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The results of the qualitative composition analysis of the dried biomass extracts of in vitro callus, cell suspension, and root cultures show that the main biologically active substances (BAS) in the medicinal plant, Rhodiola rosea, are 6-C-(1-(4-hydroxyphenyl)ethyl)aromadendrin (25 mg, yield 0.21%), 2-(3,7-dihydroxy-2-(2-hydroxypropan-2-yl)-2,3-dihydrobenzofuran-5-yl)-6,7-dihydroxychroman-4-one (23 mg, yield 0.2%), 2-(3,4-dimethoxyphenyl)-5,7-dimethoxychroman-4-one (175 mg, yield 1.5%), 5,7-dihydroxy-2-(4-hydroxy-3-(2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl)phenyl)-4H-chromen-4-one (45 mg, yi

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9

Mohammadi-Khanaposhtani, Maryam, Kiana Fahimi, Elahe Karimpour-Razkenari, et al. "Design, Synthesis and Cytotoxicity of Novel Coumarin-1,2,3-triazole-1,2,4- Oxadiazole Hybrids as Potent Anti-breast Cancer Agents." Letters in Drug Design & Discovery 16, no. 7 (2019): 818–24. http://dx.doi.org/10.2174/1570180815666180627121006.

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Background: This work reports design, synthesis, and in vitro cytotoxicity of novel coumarin-1,2,3-triazole-1,2,4-oxadiazole hybrids against three breast cancer cell lines MCF-7, MDA-MB-231, and T-47D. Methods: Synthetic procedure for the preparation of desired compounds was started from the reaction of coumarins or with propargyl bromide to give O-propargylated coumarins or 5. Then, click reaction between the later compounds and 3-aryl-5-(chloromethyl)-1,2,4-oxadiazoles afforded the desired products in good yields. Results: Among the synthesized compounds, 4-((1-((3-(4-chlorophenyl)-1,2,4-oxa

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10

Qureshi, Rahila. "Molecular docking analysis of an isoflavone derivative with the phosphatase 1 protein from Leishmania donovani." Bioinformation 16, no. 11 (2020): 942–48. http://dx.doi.org/10.6026/97320630016942.

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Leishmaniasis is one of the most neglected diseases with high morbidity and mortality rate. Severe side effects with existing drug and lack of proper vaccine encouraged us to design alternative models to combat the disease. We showed that PP1 of Leishmania donovani mediates immunomodulation in host macrophages needed for parasite survival. Therefore, it is of interest to report the molecular docking analysis of 512 isoflavone derivatives with the phosphatase 1 protein from Leishmania donovani to highlight compound 362 (5-hydroxy-5-{9-[2-methoxy-2-(2-methylfuran-3-yl) ethyl]-1H,3H,4H,10bH-pyran

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