Academic literature on the topic '621.391 (0.43)'

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Journal articles on the topic "621.391 (0.43)"

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Dyball, S., M. Rodziewicz, A. V. Madenidou, et al. "OP0013 APPLYING STANDARD CLASSIFICATION CRITERIA EXCLUDES UP TO A HALF OF ALL PATIENTS FROM CONNECTIVE TISSUE DISEASES (CTD) CLINICAL TRIALS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 9. http://dx.doi.org/10.1136/annrheumdis-2023-eular.522.

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BackgroundClassification criteria aim to identify a homogenous population of patients with a high specificity for clinical research.ObjectivesTo determine how connective tissue disease (CTD) phase III trials utilise classification criteria within their inclusion and exclusion criteria. We then applied the most commonly used classification criteria to a large cohort of patients with an existing CTD diagnosis to explore which patients would be included and excluded from trials.MethodsA comprehensive review of all major published phase III trials in CTDs was performed using clinicaltrials.gov (No
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Chiara, S., S. Lastraioli, P. Marroni, et al. "Polymorphisms in UGT1A gene family and irinotecan toxicity in patients with advanced colorectal cancer." Journal of Clinical Oncology 24, no. 18_suppl (2006): 13049. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.13049.

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13049 Background: The irinotecan active metabolite, SN38, is inactivated through glucuronidation mainly by uridine diphosphate glucuronosyltransferase (UGT) 1A1. The (TA)7 allele of a polymorphism in UGT1A1 promoter has been associated with reduced SN38-glucuronidation rate and more severe toxicity. Since other UGT1A family isoforms, the extrahepatic UGT1A7 and the hepatic UGT1A9, are involved in SN38 glucuronidation, it has been suggested that also polymorphic variants of these genes may affect irinotecan toxicity. Methods: 84 patients with advanced colorectal cancer received an irinotecan-ba
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Romero, D., G. Romero, G. Veneranda, L. Filippi, D. Racca, and G. A. Bó. "18 PREGNANCY RATES IN LACTATING DAIRY COWS TREATED WITH GONADOTROPIN-RELEASING HORMONE-BASED SYNCHRONIZATION PROGRAMS AND INSEMINATED AT A FIXED TIME." Reproduction, Fertility and Development 25, no. 1 (2013): 156. http://dx.doi.org/10.1071/rdv25n1ab18.

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An experiment was designed to compare pregnancy rates in lactating dairy cows synchronized with a 7-day CIDR-Synch or a 5-day CIDR-Synch program and to determine if the addition of a second prostaglandin F2α (PGF) injection to the 7-day CIDR-Synch program would improve pregnancy rates following fixed-time AI (FTAI). The experiments were performed on 2 dairy farms in Argentina, with year-round calving and a mixed feeding system (35% grazing plus 65% corn silage and grain). Cows (n = 621) were 39.3 ± 6.5 days in milk (DIM, mean ± SD) when they were enrolled in the program, had 2.4 ± 1.5 lactatio
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Zahalka, Ali, George Haines III, Vitaly Margulis, and Ashutosh K. Tewari. "An open-label phase 1, window-of-opportunity study of ultrasound-guided long acting periprostatic neuraxial block with ethanol in patients with high-risk prostate cancer." Journal of Clinical Oncology 43, no. 5_suppl (2025): 391. https://doi.org/10.1200/jco.2025.43.5_suppl.391.

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391 Background: Patients (pts) with high-risk prostate cancer (PCa) have an elevated risk of disease recurrence/progression after definitive therapy. These pts also exhibit increased levels of adrenergic nerve density on PCa histology. Pre-clinical evidence from murine models of PCa suggest that PCaNeurolysis of periprostatic adrenergic nerves inhibits cancer progression and metastasis by inhibiting angiogenesis, altering cancer metabolism, and inhibiting cell migration (PMC5783182). Pure Ethanol (>99%) injection for neurolysis is FDA-approved in chronic cancer pain and may have a survival
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Oto, Hanuš, Křížová Ludmila, Hajšlová Jana, et al. "Effect of increasing zearalenone levels on the coagulation properties of milk and the viability of yogurt bacteria." Czech Journal of Food Sciences 36, No. 4 (2018): 277–83. http://dx.doi.org/10.17221/391/2017-cjfs.

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The effect of increasing levels of zearalenone (ZEA) artificially supplemented to milk on the coagulation characteristics and the viability of Lactobacillus bulgaricus and Streptococcus thermophilus was examinated. Cow milk was inoculated with the yogurt culture YC-180 – YO-Flex and divided into 72, 25-ml flasks. Two samples were collected before fermentation (0 h) and remaining 70 flasks were divided into 7 groups – control (C), Z0 with 0.5 ml of ethanol and Z10, Z100, Z250, Z500, and Z1000 that were spiked with ZEA to reach the final ZEA concentrations of 10, 100, 250, 500, and 1000 µg/l, re
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Huang, Tao, Terri Beaty, Ji Li, Huijuan Liu, Wei Zhao, and Youfa Wang. "Association between dietary fat intake and insulin resistance in Chinese child twins." British Journal of Nutrition 117, no. 2 (2017): 230–36. http://dx.doi.org/10.1017/s0007114516004542.

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AbstractDietary fat intake is correlated with increased insulin resistance (IR). However, it is unknown whether gene–diet interaction modulates the association. This study estimated heritability of IR measures and the related genetic correlations with fat intake, and tested whether dietary fat intake modifies the genetic influence on type 2 diabetes (T2D)-related traits in Chinese child twins. We included 622 twins aged 7–15 years (n 311 pairs, 162 monozygotic (MZ), 149 dizygotic (DZ)) from south-eastern China. Dietary factors were measured using FFQ. Structural equation models were fit using
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Alluaibi, Abutalib B., Bahaa K. Hassan, Alaa H. Ali, and Ahmed A. Muhsen. "Determinants of conversion during laparoscopic cholecystectomy among a sample of Iraqi patients." International Surgery Journal 5, no. 7 (2018): 2455. http://dx.doi.org/10.18203/2349-2902.isj20182462.

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Background: Laparoscopic cholecystectomy has become a standard technique for gall bladder surgery of symptomatic cholelithiasis. However, conversion to open cholecystectomy is sometimes necessary. The aim of the present study was to assess the predictive factors that increase the possibility of conversion of laparoscopic cholecystectomy to open cholecystectomy.Methods: A total of 621 laparoscopic cholecystectomies were attempted at AL-Mawanee General Hospital and AL-Sader Teaching Hospital in Basrah, IRAQ from June 2012 till June 2016.Of these,43 had to be converted to open cholecystectomies.
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Perfil'ev, Nikolay, and Ol'ga V'yushina. "TILLAGE SYSTEMS INFLUENCE ON MOISTURE RESERVES, WATER CONSUMPTION AND BARLEY YIELDS." Bulletin of KSAU, no. 9 (October 29, 2024): 36–43. https://doi.org/10.36718/1819-4036-2024-9-36-43.

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The aim of research is to establish the influence of primary tillage systems of dark gray forest soil in the Northern Trans-Urals on moisture availability, water consumption of spring barley crops and its yield. The paper presents the results of long-term studies conducted in the northern forest-steppe of the Tyumen Region in a stationary experiment on average for the period of the 7th rotation of the grain-fallow crop rotation (2018–2022). All studied primary tillage systems during the sowing-emergence period had an equivalent effect on the reserves of productive moisture in the 0–30 and 0–10
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Johnson, Bruce E., Mark G. Kris, Lynne D. Berry, et al. "A multicenter effort to identify driver mutations and employ targeted therapy in patients with lung adenocarcinomas: The Lung Cancer Mutation Consortium (LCMC)." Journal of Clinical Oncology 31, no. 15_suppl (2013): 8019. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.8019.

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8019 Background: The detection of driver mutations in the EGFR and ALK genes and targeted therapy has transformed treatment of lung cancer. The LCMC was established in 2009 to assay lung adenocarcinomas for driver genomic alterations in 10 genes and to study and treat patients by their molecular subtypes. Methods: The 14-member LCMC enrolled patients with metastatic adenocarcinoma of the lung and tested their tumors in CLIA laboratories for KRAS, EGFR, HER2, BRAF, PIK3CA, AKT1, MEK1, and NRAS mutations using multiplexed assays, and for ALK rearrangements and MET amplifications using fluorescen
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Foeldvari, I., J. Klotsche, O. Kasapcopur, et al. "POS0079 PATIENTS WITH JUVENILE SYSTEMIC SCLEROSIS HAVE A DISTINCT PATTERN OF ORGAN INVOLVEMENT.RESULTS FROM THE JUVENILE SYSTEMIC SCLEROSIS INCEPTION COHORT. WWW.JUVENILE-SCLERODERMA.COM." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 247.2–247. http://dx.doi.org/10.1136/annrheumdis-2021-eular.799.

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Background:Juvenile systemic sclerosis (jSSc) is a rare disease with a prevalence of around 3 in 1,000,000 children. To better capture the clinical manifestations of jSSc the juvenile systemic sclerosis inception cohort (jSScC) has been prospectively enrolling patients with predetermined clinical variables over the past 12 years. One of the goals is to study the demographic, clinical features, and physician and patient reported outcome differences between those with juvenile limited cutaneous (lc) compared to diffuse cutaneous (dc) disease subtypes, to determine if characteristics are similar
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Book chapters on the topic "621.391 (0.43)"

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Kunst, Ljerka. "Preparation of Physiologically Active Chloroplasts from Arabidopsis." In Arabidopsis Protocols. Humana Press, 1998. http://dx.doi.org/10.1385/0-89603-391-0:43.

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