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1

Hong, Mun K., and Eyal Herzog, eds. Acute Coronary Syndrome. Springer London, 2008. http://dx.doi.org/10.1007/978-1-84628-869-2.

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2

Herzog, Eyal, and Farooq Chaudhry, eds. Echocardiography in Acute Coronary Syndrome. Springer London, 2009. http://dx.doi.org/10.1007/978-1-84882-027-2.

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3

K, Hong Mun, and Herzog Eyal, eds. Acute coronary syndrome: Multidisciplinary and pathway-based approach. Springer, 2008.

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4

Workshop on Research Priorities for Care of Acute Coronary Syndrome at Non-Tertiary Care Level of Low Resource Settings (2005 New Delhi, India). Report of Workshop on Research Priorities for Care of Acute Coronary Syndrome at Non-Tertiary Care Level of Low Resource Settings, August 18-19, 2005, New Delhi, India. Scientific Secretariat, Initiative for Cardiovascular Health Research in Developing Countries, 2005.

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5

Xanthos, Theodoros, and Theodoros Xanthos. Drugs in cardiopulmonary resuscitation. Nova Science Publishers, 2011.

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6

Xanthos, Theodoros. Drugs in cardiopulmonary resuscitation. Nova Science Publishers, 2011.

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7

ACS Essentials: Acute Coronary Syndromes. 2nd ed. Not Avail, 2005.

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8

Alonso Salinas, Gonzalo Luis, Marina Pascual Izco, Covadonga Fernández-Golfín, Luigi P. Badano, and José Luis Zamorano. Ischaemic heart disease: acute coronary syndrome. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0029.

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Transthoracic echocardiography (TTE) is a non-invasive and accessible tool that should be widely used in the evaluation of patients with suspected or known acute coronary syndrome (ACS). Its role is crucial in the management of patients with suspected ACS without electrocardiographic changes or elevation of cardiac markers, allowing the formulation of differential diagnosis between cardiac and extracardiac aetiologies. If the ACS is confirmed, initial assessment of regional and global left and right ventricle contractile function is fundamental in establishing the management strategy and may h
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9

AlJaroudi, Wael. Risk Assessment in Acute Coronary Syndromes. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199392094.003.0013.

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Acute coronary syndromes (ACS) include unstable angina pectoris (UAP), non-ST elevation (NSTEMI), and ST elevation acute myocardial infarction (STEMI). Each year, more than 2 million people are hospitalized with ACS in the United States. The initial treatment has evolved over the last few decades from conservative management to early reperfusion therapy. Medical therapy has also significantly changed with the use of newer more potent antiplatelet agents, beta-blockers, angiotensin converting enzyme inhibitors, statins, and anti-anginal drugs, which have resulted in improvement of patient care
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10

Valgimigli, Marco, and Marco Angelillis. Treatment of non-ST elevation acute coronary syndromes. Edited by Stefan James. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0311.

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Treatment of patients presenting with a non-ST elevation acute coronary syndrome (NSTE-ACS) aims at immediate relief of ischaemia and the prevention of serious adverse events, including death, myocardial (re)infarction, and life-threatening arrhythmias. In NSTE-ACS, patient management is guided by risk stratification (troponin, electrocardiogram, risk scores, etc.). Treatment options include anti-ischaemic and antithrombotic drugs and coronary revascularization including percutaneous coronary interventions, or coronary artery bypass grafting. While long-term secondary prevention with aspirin m
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11

Dawson, Dana, and Keith Fox. Anti-Platelet and Anti-Thrombotic Therapy Post-AMI. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199544769.003.0004.

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• Acute coronary syndromes (ACS) encompass a spectrum of presentations which include unstable angina, non-ST-elevation myocardial infarction (NSTEMI or NSTE-ACS), and ST-elevation myocardial infarction (STEMI or STE-ACS)• Anti-platelet and anti-thrombotic agents are administered as ancillary therapy to myocardial reperfusion in patients presenting with an acute coronary syndrome, to maintain the patency of the infarct-related coronary artery• More specific and potent inhibitors of platelet activation and of the coagulation cascade are emerging with the aim being to further improve clinical out
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12

Visser, Frans, and Maarten Simoons. Percutaneous Coronary Intervention and Thrombolysis in AMI & other ACS. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199544769.003.0003.

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• Acute coronary syndromes (ACS) comprise an evolving acute myocardial infarction (AMI) presenting with or without ST-elevation and unstable angina• Patients presenting with an ST-elevation MI require immediate reperfusion therapy by primary percutaneous coronary intervention (PCI) or, if such is not available, thrombolysis• Cardiologists, emergency care physicians, general practictioners and ambulance services should collaborate to develop a national or regional system to optimise AMI therapy, given the national or local facilities and available resources• A subgroup of high-risk patients pre
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13

Stacey, Victoria. Cardiology. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199592777.003.0009.

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Acute coronary syndrome (ACS) - Investigations in ACS - Management of ACS - Management of STEMI/new LBBB - Atrial fibrillation - Arrhythmias - Transient loss of consciousness - Sudden cardiac death (SCD) - Heart failure - Hypertensive emergencies - Infective endocarditis - Pericardial disease - SAQs
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14

Kotsis, Eleni, Jamie M. Zorn, and Grace Lim. Vessels. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0051.

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Acute coronary syndrome (ACS) in pregnancy is generally considered a rare but potentially life-threatening occurrence. Recent societal trends, including improvements in infertility treatments and professional demands, have contributed to many women delaying pregnancy. The rise in average maternal age means that risks for coronary artery disease and subsequent ACS events in pregnancy are likely to be more frequently encountered by the obstetric clinician. A thorough understanding of the risks, pathophysiology, management, and treatment of ACS and its ramifications in the pregnant patient is req
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15

Kasliwal, R. Acute Coronary Syndrome. Elsevier - Health Sciences Division, 2009.

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16

Alexander, Lori, NetCE, and CE Resource. Acute Coronary Syndrome. CE Resource, Incorporated, 2018.

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17

Alexander, Lori, NetCE, and CE Resource. Acute Coronary Syndrome. CE Resource, Incorporated, 2021.

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18

Brizzio, Mariano E., Anjan Kumar Dasgupta, Amparo Galán, and Iwao Emura. Acute Coronary Syndrome. DI Press, 2022.

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19

Dunn, Mia. Acute Coronary Syndrome. American Medical Publishers, 2021.

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20

Soman, Prem, and James E. Udelson. Imaging Patients with Chest Pain in the Emergency Department. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199392094.003.0019.

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The six-to-eight million people who present to emergency departments (EDs) across the U.S. each year for the evaluation of chest pain present a unique challenge to physicians.(1) Less than a third of these patients are eventually diagnosed with coronary artery disease (CAD).(2,3) However, a small percentage of patients with acute cardiac ischemia and an acute coronary syndrome (ACS) are inadvertently discharged, with potential adverse consequences.(2,4-6) Concerns about patient safety and malpractice litigation has resulted in the adoption of a practice paradigm that involves observation and t
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21

Mannucci, Pier Mannuccio, and Maddalena Lettino. Bleeding and haemostasis disorders. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0070_update_003.

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The main cause of haemostasis defects and related bleeding complications in patients with acute coronary syndromes admitted to the intensive cardiac care unit is the use of multiple antithrombotic drugs, alone or concomitantly with invasive procedures such as percutaneous coronary intervention with stent deployment and coronary artery bypass surgery. These drugs, that act upon several components of haemostasis (platelet function, coagulation, fibrinolysis), are associated with bleeding complications, particularly in elderly patients (more so in women than in men), those who are underweight, an
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22

Katritsis, Demosthenes G., Bernard J. Gersh, and A. John Camm. Non-ST elevation acute coronary syndromes. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199685288.003.0538_update_004.

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Diagnosis and current pharmacological and interventional management of unstable angina/non-ST elevation myocardial infarction are presented in this chapter. Recent recommendations by the ACC/AHA and the ESC have been summarized and tabulated.
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23

Mannucci, Pier Mannuccio. Bleeding and haemostasis disorders. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0070.

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The main cause of haemostasis defects and related bleeding complications in patients with acute coronary syndromes admitted to the intensive cardiac care unit is the use of multiple antithrombotic drugs, alone or concomitantly with invasive procedures such as percutaneous coronary intervention with stent deployment and coronary artery bypass surgery. These drugs, that act upon several components of haemostasis (platelet function, coagulation, fibrinolysis), are associated with bleeding complications, particularly in elderly patients (more so in women than in men), those who are underweight, an
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24

Mannucci, Pier Mannuccio. Bleeding and haemostasis disorders. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0070_update_001.

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The main cause of haemostasis defects and related bleeding complications in patients with acute coronary syndromes admitted to the intensive cardiac care unit is the use of multiple antithrombotic drugs, alone or concomitantly with invasive procedures such as percutaneous coronary intervention with stent deployment and coronary artery bypass surgery. These drugs, that act upon several components of haemostasis (platelet function, coagulation, fibrinolysis), are associated with bleeding complications, particularly in elderly patients (more so in women than in men), those who are underweight, an
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25

Mannucci, Pier Mannuccio. Bleeding and haemostasis disorders. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0070_update_002.

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The main cause of haemostasis defects and related bleeding complications in patients with acute coronary syndromes admitted to the intensive cardiac care unit is the use of multiple antithrombotic drugs, alone or concomitantly with invasive procedures such as percutaneous coronary intervention with stent deployment and coronary artery bypass surgery. These drugs, that act upon several components of haemostasis (platelet function, coagulation, fibrinolysis), are associated with bleeding complications, particularly in elderly patients (more so in women than in men), those who are underweight, an
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26

Tian, Jinwei, Zhao Wang, and Minjie Lu, eds. Multimodality Imaging in Acute Coronary Syndrome. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88976-425-9.

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27

Mandell, Joyce E. Ventricular Fibrillation and Acute Coronary Syndrome. Nova Science Publishers, Incorporated, 2011.

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28

Mosby. Acute Coronary Syndromes And Stroke: 2nd edition (Mosby's Acls Lecture). C.V. Mosby, 2003.

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29

D’Auria, Stephen, and Ravi Ramani. Chest Pain and Acute Coronary Syndrome (DRAFT). Edited by Raghavan Murugan and Joseph M. Darby. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190612474.003.0011.

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Chest pain is a common presenting complaint faced by the rapid response team (RRT), and can herald a serious process such as acute coronary syndrome or aortic dissection, or be secondary to a minor muscle strain. A methodical approach to chest pain is necessary to avoid premature diagnostic closure. One of the most feared diagnoses is a myocardial infarction. Fortunately, there are well-established guidelines describing the necessary steps for treatment of both ST elevation myocardial infarction (STEMI) and non-ST elevation myocardial infarction (NSTEMI). This chapter will address the differen
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30

Dardenay, Enzo, and Charles Cocheret. Acute Coronary Syndrome: Symptoms, Treatment and Prevention. Nova Science Publishers, Incorporated, 2014.

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31

Lee, Christoph I. CT Angiography for Discharge of Acute Coronary Syndrome. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190223700.003.0021.

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This chapter, found in the chest pain section of the book, provides a succinct synopsis of a key study examining the use of computed tomography (CT) angiography for discharging patients with acute coronary syndrome from the emergency department. This summary outlines the study methodology and design, major results, limitations and criticisms, related studies and additional information, and clinical implications. The study showed that a negative coronary CT angiography examination can be used to safely expedite the discharge of low-to-intermediate risk patients who present to emergency departme
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32

Diaz, Joan. Acute Coronary Syndrome: Diagnosis, Management and Research Insights. Nova Science Publishers, Incorporated, 2017.

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33

Evidence-Based Management of the Acute Coronary Syndrome. Hanley & Belfus, 2001.

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34

Christopher P., M.D. Cannon. Contemporary Diagnosis and Management of Acute Coronary Syndrome. Handbooks in Health Care Company, 2006.

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35

Handberg, Eileen, and R. David Anderson. Acute Coronary Syndrome: Urgent and Follow-Up Care. Cardiotext Publishing, 2017.

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36

Parale, Gurunath. Acute Coronary Syndrome with Comorbidities: A Therapeutic Challenge. Jaypee Brothers Medical Publishers, 2020.

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37

Handberg, Eileen, and R. David Anderson. Acute Coronary Syndrome: Urgent and Follow-Up Care. Cardiotext Publishing, 2017.

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38

Shirodaria, Cheerag, and Sam Dawkins. Acute coronary syndromes. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0090.

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The term ‘acute coronary syndrome’ includes unstable angina, ST-elevation myocardial infarction (STEMI), and non-ST-elevation myocardial infarction (NSTEMI). The difference between these three syndromes is as follows. In STEMI and NSTEMI, there is evidence of myocardial necrosis, as evidenced by raised cardiac enzymes, specifically, the very sensitive cardiac biomarker troponin. STEMI is diagnosed when the ECG shows persisting ST elevation in an appropriate territory consistent with STEMI whereas, in NSTEMI, there can be any or no ECG changes, or very transient, self-limiting ST elevation. In
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39

Herzog, Eyal, and Farooq Chaudhry. Echocardiography in Acute Coronary Syndrome: Diagnosis, Treatment and Prevention. Springer London, Limited, 2009.

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40

Echocardiography In Acute Coronary Syndrome Diagnosis Treatment And Prevention. Springer, 2009.

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41

Purcell, Henry, and Richard T., M.D. Katz. Rapid Reference to Acute Coronary Syndrome (Rapid Reference Series). C.V. Mosby, 2006.

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42

Acute Coronary Syndromes in Clinical Practice. Springer Mycopy Us, 2009.

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43

Acute Coronary Syndromes In Clinical Practice. Springer, 2008.

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44

Kočka, Viktor, Steen Dalby Kristensen, William Wijns, Petr Toušek, and Petr Widimský. Percutaneous coronary interventions in acute coronary syndromes. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0047.

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Three different guidelines of the European Society of Cardiology cover the field of percutaneous coronary interventions. Their main recommendations are the following:All patients with an ST-segment elevation myocardial infarction should undergo immediate coronary angiography and percutaneous coronary intervention as soon as possible after the first medical contact. Thrombolysis can be used as an alternative reperfusion therapy if the time delay to primary percutaneous coronary intervention is more than 2 hoursPatients with very high-risk non-ST-segment elevation acute coronary syndromes (recur
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45

Kočka, Viktor, Steen Dalby Kristensen, William Wijns, Petr Toušek, and Petr Widimský. Percutaneous coronary interventions in acute coronary syndromes. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0047_update_001.

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Three different guidelines of the European Society of Cardiology cover the field of percutaneous coronary interventions. Their main recommendations are the following:All patients with an ST-segment elevation myocardial infarction should undergo immediate coronary angiography and percutaneous coronary intervention as soon as possible after the first medical contact. Thrombolysis can be used as an alternative reperfusion therapy if the time delay to primary percutaneous coronary intervention is more than 2 hoursPatients with very high-risk non-ST-segment elevation acute coronary syndromes (recur
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46

Kočka, Viktor, Steen Dalby Kristensen, William Wijns, Petr Toušek, and Petr Widimský. Percutaneous coronary interventions in acute coronary syndromes. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0047_update_002.

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Three different guidelines of the European Society of Cardiology cover the field of percutaneous coronary interventions. Their main recommendations are the following: All patients with an ST-segment elevation myocardial infarction should undergo immediate coronary angiography and percutaneous coronary intervention as soon as possible after the first medical contact. Thrombolysis can be used as an alternative reperfusion therapy if the time delay to primary percutaneous coronary intervention is more than 2 hours. Patients with very high-risk non-ST-segment elevation acute coronary syndromes (re
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47

Kočka, Viktor, Steen Dalby Kristensen, William Wijns, Petr Toušek, and Petr Widimský. Percutaneous coronary interventions in acute coronary syndromes. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0047_update_003.

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Three different guidelines of the European Society of Cardiology cover the field of percutaneous coronary interventions. Their main recommendations are the following: All patients with an ST-segment elevation myocardial infarction should undergo immediate coronary angiography and percutaneous coronary intervention as soon as possible after the first medical contact. Thrombolysis can be used as an alternative reperfusion therapy if the time delay to primary percutaneous coronary intervention is more than 2 hours. Patients with very high-risk non-ST-segment elevation acute coronary syndromes (re
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48

Clopidogrel response in acute coronary syndrome: Clinical implications and emerging therapies. Nova Science Publishers, 2010.

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49

Giannitsis, Evangelos, and Hugo A. Katus. Biomarkers in acute coronary syndromes. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0036.

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Biomarker testing in the evaluation of a patient with acute chest pain is best established for cardiac troponins that allow the diagnosis of myocardial infarction, risk estimation of short- and long-term risk of death and myocardial infarction, and guidance of pharmacological therapy, as well as the need and timing of invasive strategy. Newer, more sensitive troponin assays have become commercially available and have the capability to detect myocardial infarction earlier and more sensitively than standard assays, but they are hampered by a lack of clinical specificity, i.e. the ability to disc
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50

Giannitsis, Evangelos, and Hugo A. Katus. Biomarkers in acute coronary syndromes. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0036_update_001.

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Biomarker testing in the evaluation of a patient with acute chest pain is best established for cardiac troponins that allow the diagnosis of myocardial infarction, risk estimation of short- and long-term risk of death and myocardial infarction, and guidance of pharmacological therapy, as well as the need and timing of invasive strategy. Newer, more sensitive troponin assays have become commercially available and have the capability to detect myocardial infarction earlier and more sensitively than standard assays, but they are hampered by a lack of clinical specificity, i.e. the ability to disc
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