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Dissertations / Theses on the topic 'AFM Modes'

Author: Grafiati

Published: 6 September 2023

Last updated: 31 July 2025

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1

Valloire, Hugo. "Développements de modes avancés de microscopie à force piézoélectrique pour films minces piézoélectriques et ferroélectriques." Electronic Thesis or Diss., Université Grenoble Alpes, 2024. http://www.theses.fr/2024GRALY063.

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De nombreuses applications actuelles dans le secteur de la microélectronique reposent sur l’utilisation de matériaux piézoélectriques et ferroélectriques sous forme de films minces. Par exemple, des dispositifs MEMS incluant les capteurs, actionneurs et convertisseurs d'énergie tirent profit des propriétés piézoélectriques des matériaux. Par ailleurs, l'émergence de nombreux sujets de recherche a fait suite à la découverte du potentiel de certains de ces matériaux pour les dispositifs microélectroniques. C’est par exemple le cas de l'utilisation du HfO2 pour ses propriétés ferroélectriques dan

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2

Devailly, Clémence. "Fluctuations thermiques - un outil pour étudier les fluides simples et binaires à l'échelle du micron." Thesis, Lyon, École normale supérieure, 2014. http://www.theses.fr/2014ENSL0976.

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Les transitions de phase près d'un point critique - dites du second ordre - sont un sujet toujours d'actualité en raison des nombreux phénomènes critiques intéressants tels que la force de Casimir critique, les problèmes de confinements ou les phénomènes hors d'équilibre suivant une trempe au point critique. Cette thèse vise à étudier expérimentalement certains phénomènes engendrés près d'un point critique. La thèse est divisée en deux axes : le premier consiste à développer plusieurs systèmes expérimentaux qui permettront de mesurer essentiellement la viscosité, par l'intermédiaire des fluctu

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3

Oral, Hasan Giray. "Modeling time-resolved interaction force mode AFM imaging." Thesis, Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/43691.

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Intermittent contact mode atomic force microscopy has been widely employed for simultaneous topography imaging and material characterization. The work in the literature includes both qualitative and quantitative methods. Regular AFM cantilevers are generally used in these methods, yet these cantilevers come with certain limitations. These limitations result from the very nature of cantilever probes. They are passive force sensors with insufficient damping. This prevents having active and complete control on tip-sample forces, causing sample damage and inaccurate topography measurement. Ideally

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4

Billingsley, Daniel Jeffrey. "Convergent transcription and nested gene models studied by AFM." Thesis, University of Leeds, 2012. http://etheses.whiterose.ac.uk/3149/.

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Genomic DNA is organised in complex spatial arrangements, and a given stretch of DNA may encode more than one gene. In some cases one gene may be entirely contained within a region of the DNA already occupied by another larger gene. The presence of these nested genes, often situated in introns and in the opposite orientation, poses important implications with regards to gene expression, function and regulation. A consequence of the nested gene arrangement is convergent transcription, occurring when two promoters on opposite DNA strands are active. Elucidating the mechanics of multiple interact

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5

Yurtsever, Ayhan. "Nanotribological surface characterization by frequency modulated torsional resonance mode AFM." Diss., kostenfrei, 2008. http://edoc.ub.uni-muenchen.de/8718/.

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6

Stone, Peter (Peter Robert). "A new model for electric force microscopy and its application for electrostatically generated phase difference in tapping mode AFM." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/32855.

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Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2005.<br>Includes bibliographical references (leaf 37).<br>The harmonic force balance method was used to model and simulate electric force microscopy (EFM) and electrostatically generated phase difference in tapping mode AFM (EPTA) measurements. Simulations show that the harmonic force balance approach matches and explains EFM and EPTA experimental results well. Simulations also show that the model depended on both geometric and materials parameters. The harmonic force balance model was subsequent

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7

Nasrallah, Hussein. "Capillary adhesion and friction : an approach with the AFM Circular Mode." Phd thesis, Université du Maine, 2011. http://tel.archives-ouvertes.fr/tel-00651818.

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The aim of this thesis is concerned with the influence of sliding velocity on capillary adhesion at the nanometer scale. In ambient conditions, capillary condensation which is a thermally activated process, allows the formation of a capillary meniscus at the interface between an atomic force microscope (AFM) probe and a substrate. This capillary meniscus leads to a capillary force that acts as an additional normal load on the tip, and affects the adhesion and friction forces. The Atomic Force Microscopy (AFM) offers interesting opportunities for the measurement of surface properties at the nan

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8

Hida, H., M. Shikida, K. Fukuzawa, et al. "Quartz tuning-fork type AFM probe operated in Anti-phase Vibration Mode." IEEE, 2006. http://hdl.handle.net/2237/9554.

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9

Lin, Zhen. "AFM electrical mode development for nanostructure semiconductor study : application on Ge / Si nanostructure." Lyon, INSA, 2010. http://theses.insa-lyon.fr/publication/2010ISAL0135/these.pdf.

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Aujourd'hui, la technologie des semi-conducteurs est confrontée au défi de la réduction ultime de la taille des composants pour augmenter la performance des appareillages électroniques en les miniaturisant. Cette forte réduction d'échelle provoque un développement considérable des techniques de microscopie pour révéler de nouvelles caractéristiques physiques à l'échelle nanométrique. La compréhension de ces nouvelles propriétés à l'échelle du nanomètre est donc de première importance. Dans ce travail, l’utilisation et l’application des techniques de caractérisation des propriétés électriques p

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10

Sebinelli, Heitor Gobbi. "Estudo de proteolipossomos constituídos de Na,K-ATPase utilizando a técnica de microscopia de força atômica." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/59/59138/tde-21092016-140434/.

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A Na, K-ATPase (NKA) é uma proteína de membrana encontrada em organismos eucariotos multicelulares cuja atividade e funções já são amplamente discutidas na literatura. Sua unidade funcional corresponde a um heterodímero formado por duas subunidades , com regiões transmembrana. Espécies multiméricas como dímeros e tetrâmeros dessa enzima também são conhecidos por exercer atividade enzimática. As interações lipídio-proteína são intrínsecas para a NKA, por tal motivo, proteolipossomos constituídos de DPPC e DPPC:DPPE foram preparados por co-solubilização. Como controle, lipossomos de mesma compo

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11

Horstmeier, Sebastian [Verfasser]. "Dynamische AFM-Kraftspektroskopie an Desoxyribonukleinsäure im frequenz-modulierten Modus mit konstanter Anregung / Sebastian Horstmeier." Bielefeld : Universitätsbibliothek Bielefeld, 2013. http://d-nb.info/1045878561/34.

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12

El-Rifai, Khalid 1979. "Control of AFMs in contact mode." Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/17597.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2003.<br>Includes bibliographical references (leaves 71-74).<br>The Atomic Force Microscope (AFM) is a high precision surface characterization tool commonly used in Nano-technology, Bio-technology, semiconductors, MEMS, and life sciences' applications. As most versatile systems, AFM offers little guarantees on achieving repeatable satisfactory operation. This is the case as AFMs are not used to perform a single predictable task. AFM systems are feedback regulators, which rely on photodiode detector (PSD) sen

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13

Rozmovits, Linda 1959. "A.M. Klein and modernism." Thesis, McGill University, 1988. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=64004.

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14

Fermé, Eduardo. "On the Logic of Theory Change : Extending the AGM Model." Doctoral thesis, KTH, Filosofi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-29601.

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This thesis consists in six articles and a comprehensive summary. • The pourpose of the summary is to introduce the AGM theory of belief change and to exemplify the diversity and significance of the research that has been inspired by the AGM article in the last 25 years. The research areas associated with AGM was divided in three parts: criticisms, where we discussed some of the more common criticisms of AGM. Extensions where the most common extensions and variations of AGM are presented and applications where we provided an overview of applications and connections with other areas of research

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15

Sarker, Md Omar Faruque. "Self-regulated multi-robot task allocation." Thesis, University of South Wales, 2010. https://pure.southwales.ac.uk/en/studentthesis/selfregulated-multirobot-task-allocation(4b92f28f-c712-4e75-955f-97b4e5bf12dd).html.

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To deploy a large group of autonomous robots in dynamic multi-tasking environments, a suitable multi-robot task-allocation (MRTA) solution is required. This must be scalable to variable number of robots and tasks. Recent studies show that biology-inspired self-organized approaches can effectively handle task-allocation in large multi-robot systems. However most existing MRTA approaches have overlooked the role of different communication and sensing strategies found in selfregulated biological societies. This dissertation proposes to solve the MRTA problem using a set of previously published ge

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16

Khanal, Dipesh. "Toxicological considerations of nanoparticles using two and three dimensional liver models: Holistic approach to nanoparticle characterization and nanotoxicity assessment." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/18637.

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Nanoparticles became ‘indispensable’ components of cosmetics, food products, biosensor and therapeutics. Daily consumption of nanoparticles exceeds 1 mg/kg of body mass for adults and more importantly 2 mg/kg of body mass for kids (few trillions of nanoparticles per day). There is increasing evidence that nanoparticles contribute to the loss of cell function and may be responsible for increase in auto immune disease, asthma and autism. The impact of nanomaterials on health still remains unexplored. Conventional nanosafety assessment tools have limited capability and resolution, these methods a

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17

Spitzner, Eike-Christian. "Subsurface and MUSIC-Mode Atomic Force Microscopy." Doctoral thesis, Universitätsbibliothek Chemnitz, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-94864.

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Ziel dieser Arbeit war die Entwicklung neuer Methoden in der Rasterkraftmikroskopie, um die Qualität und Interpretierbarkeit von Oberflächenabbildungen auf der Nanometerskala, vor allem jener sehr weicher Proben, entscheidend zu verbessern. Der für polymere und biologische Materialien standardmäßig verwendete intermittierende Kontaktmodus führt auf weichen Oberflächen zu verfälschten Abbildungen der Topographie und der mechanischen Eigenschaften. In dieser Arbeit wurden Techniken entwickelt, die einerseits zerstörungsfreie, tiefenaufgelöste Rasterkraftmikroskopie und andererseits Einzelmessung

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18

Vecchiola, Aymeric. "Développement d’une imagerie de résistance électrique locale par AFM à pointe conductrice en mode contact intermittent." Thesis, Paris 11, 2015. http://www.theses.fr/2015PA112058/document.

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Le microscope à force atomique (AFM) permet de caractériser avec une excellente résolution spatiale les surfaces d’échantillons de différentes natures et peut être mis en œuvre dans des milieux variés. Cette versatilité a favorisé le développement d’un grand nombre de techniques dérivées, destinées à investiguer diverses propriétés physiques locales. Le LGEP a ainsi réalisé un module, le Résiscope, capable de mesurer la résistance électrique locale à la surface d’un échantillon polarisé en continu, sur une gamme de 11 décades. Mise au point en mode contact, où la pointe exerce en permanence un

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19

Wang, Kathleen F. "Characterizing molecular-scale interactions between antimicrobial peptides and model cell membranes." Digital WPI, 2014. https://digitalcommons.wpi.edu/etd-dissertations/153.

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Due to the escalating challenge of antibiotic resistance in bacteria over the past several decades, interest in the identification and development of antibiotic alternatives has intensified. Antimicrobial peptides (AMPs), which serve as part of the innate immune systems of most eukaryotic organisms, are being researched extensively as potential alternatives. However, the mechanism behind their bactericidal capabilities is not well understood. Previous studies have suggested that AMPs may first attach to the cell membranes, leading to pore formation caused by peptide insertion, lipid removal i

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20

Jarmusik, Keith Edward. "An Improved Model for Interpreting Molecular Scale Electrostatic Interactions." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1275666964.

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21

Chai, Hao. "Statistical inference in high dimensional linear and AFT models." Diss., University of Iowa, 2014. https://ir.uiowa.edu/etd/1303.

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Variable selection procedures for high dimensional data have been proposed and studied by a large amount of literature in the last few years. Most of the previous research focuses on the selection properties as well as the point estimation properties. In this paper, our goal is to construct the confidence intervals for some low-dimensional parameters in the high-dimensional setting. The models we study are the partially penalized linear and accelerated failure time models in the high-dimensional setting. In our model setup, all variables are split into two groups. The first group consists of a

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22

Singh, Amit Kumar. "Caractérisation des Mémoires Non-Volatiles Résistives par Microscopie à Force Atomique en mode Conduction (C-AFM) sous Ultravide." Thesis, Université Grenoble Alpes (ComUE), 2019. http://www.theses.fr/2019GREAT033.

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Les mémoires sont à la base de tout système électronique avec lequel nous interagissons dans notre vie quotidienne et deviennent de plus en plus important jour après jour à notre époque. Les fonctionnalités et les performances croissantes des produits électroniques tels que les appareils photo numériques, les téléphones cellulaires, les ordinateurs personnels, les disques durs, etc., nécessitent une amélioration continue de ses fonctionnalités. La technologie Flash à grille flottante est la principale technologie NVM utilisée sur le marché actuellement. Néanmoins, la technologie Flash pose de

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23

Horne, Jimmy D. "Modeling optical turbulence with coamps during two observation periods at Vandenberg AFB /." Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2004. http://library.nps.navy.mil/uhtbin/hyperion/04Mar%5FHorne.pdf.

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Thesis (M.S. in Meteorology and Physical Oceanography)--Naval Postgraduate School, March 2004.<br>Thesis advisor(s): Douglas Miller. Includes bibliographical references (p. 67-70). Also available online.

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24

Dressel, Frank. "Sequenz, Energie, Struktur - Untersuchungen zur Beziehung zwischen Primär- und Tertiärstruktur in globulären und Membran-Proteinen." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2008. http://nbn-resolving.de/urn:nbn:de:bsz:14-ds-1222781322751-68621.

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Proteine spielen auf der zellulären Ebene eines Organismus eine fundamentale Rolle. Sie sind quasi die „Maschinen“ der Zelle. Ihre Bedeutung wird nicht zuletzt in ihrem Namen deutlich, welcher 1838 erstmals von J. Berzelius verwendet wurde und „das Erste“, „das Wichtigste“ bedeutet. Proteine sind aus Aminosäuren aufgebaute Moleküle. Unter physiologischen Bedingungen besitzen sie eine definierte dreidimensionale Gestalt, welche für ihre biologische Funktion bestimmend ist. Es wird heutzutage davon ausgegangen, dass diese dreidimensionale, stabile Struktur von Proteinen eindeutig durch die Abfol

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25

PERISSINOTTO, FABIO. "Lipid raft formation and lipid-protein interactions in model membranes." Doctoral thesis, Università degli Studi di Trieste, 2018. http://hdl.handle.net/11368/2919798.

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The biological membranes of eukaryotic organisms contain functional, highly dynamic nano-domains called "lipid rafts" (LRs) which are enriched in cholesterol, sphingolipids and GPI-anchor proteins. They are involved in several biological processes which implicate or are mediated by the plasma membrane. Moreover, LRs seem to have a critical role in the onset of some neurodegenerative diseases such as the Alzheimer’s disease (AD), Parkinson’s disease (PD) and Prion protein disorders. In the last two decades, the complexity of studying such domains in living cells has caused a growing interest in

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26

Oh, Yunje. "Prediction of steady state response in dynamic mode atomic force microscopy and its applications in nano-metrology." The Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=osu1135222817.

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27

Parlak, Zehra. "Quantitative imaging of subsurface structures and mechanical properties at nanoscale using atomic force microscope." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/37181.

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This dissertation focuses on quantitative subsurface and mechanical properties imaging potential of AFM probes. Extensive modeling of AFM probes are presented for thorough understanding of capabilities and limitations of current techniques, these models are verified by various experiments, and different methods are developed by utilizing force-sensing integrated read-out active tip (FIRAT), which is an active AFM probe with broad bandwidth. For quantitative subsurface imaging, a 3-D FEA model of AFM tip-sample contact is developed and this model can simulate AFM tip scan on nanoscale-sized bur

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28

Luu, Ngoc Mai. "Sondes à nanotubes de carbone mono-paroi pour la microscopie à force atomique : synthèse et imagerie à l'air et en milieu liquide." Thesis, Bordeaux, 2019. http://www.theses.fr/2019BORD0071/document.

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La microscopie à force atomique (AFM) permet d’étudier à l’échelle nanométrique la surface d’échantillons. Elle offre de nombreux avantages par rapport aux microscopes optiques et aux microscopes électroniques, tout en évitant des étapes de préparation particulières : pas de nécessité de congeler, de métalliser ou de teinter l’échantillon ni de travailler sous vide. La résolution de l'imagerie AFM est principalement déterminée par la morphologie de la sonde utilisée et peut atteindre la résolution moléculaire. Toutefois, les sondes en silicium sont très fragiles. De plus, leur forme pyramidale

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29

AZİZOĞLU, YAĞIZ. "Micromechanical Numeric Investigation of Fiber Bonds in 3D Network Structures." Thesis, KTH, Hållfasthetslära (Avd.), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-144036.

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In manufacturing of paper and paperboard, optimized fiber usage has crucial importance for process efficiency and profitability. Dry strength of paper is one of the important quality criteria, which can be improved by adding dry strength additive that affect fiber to fiber bonding. This study is using the micromechanical simulations which assist interpretation of the experimental results concerning the effect of strength additives. A finite element model for 3D dry fiber network was constructed to study the effect of bond strength, bond area and the number of bonds numerically on the strength

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30

Buchoux, Julien. "Nanotubes de carbone comme sondes en microscopie à force atomique : nanomécanique et étude à l’interface air-liquide de fluides complexes." Thesis, Bordeaux 1, 2011. http://www.theses.fr/2011BOR14221/document.

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La microscopie à force atomique exploite les interactions entre une sonde et un échantillon. Les nanotubes de carbone représentent la sonde idéale, ils sont: fins, robustes, peu réactifs et ont un haut rapport d'aspect. L'utilisation à grande échelle des sondes à nanotubes de carbone passe par l'étude de leur comportement mécanique en contact avec une surface. Nous étudions deux types de sondes: les sondes avec nanotubes multiparois et les sondes avec nanotubes monoparois. Pour les nanotubes multiparois nous avons utilisé trois mode de fonctionnement AFM différents que sont les modes contact,

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31

Baiti, Risa Nurin. "Characterization of nano-mechanical properties of biological lipid membranes with circular mode atomic force microscopy." Thesis, Compiègne, 2017. http://www.theses.fr/2017COMP2403/document.

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Les membranes cellulaires sont impliquées dans de nombreux processus cellulaires : la diffusion des médicaments et des ions, la transduction des signaux, la génération d'énergie, le développement cellulaire (fusion et fission). Les bicouches phospholipides sont les principaux composants des membranes cellulaires, elles constituent une barrière dynamique protégeant les réactions biochimiques cellulaires. La détermination des propriétés biochimiques et mécaniques des bicouches lipidiques et leur évolution avec les conditions environnementales est nécessaire pour étudier la nature des processus c

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32

Kelly, Joseph. "Advances in the Normal-Normal Hierarchical Model." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11498.

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33

Darwich, Samer. "Colloidal Gold Nanoparticules : A study of their Drying-Mediated Assembly in Mesoscale Aggregation Patterns and of their AFM Assisted Nanomanipulation on Model Solid Surfaces." Phd thesis, Université de Haute Alsace - Mulhouse, 2011. http://tel.archives-ouvertes.fr/tel-00718640.

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This work deals with the study of the drying-mediated assembly of colloidal gold nanoparticles (Au NPs) in mesoscale aggregation patterns and their manipulation by atomic force microscopy (AFM) on model surfaces. The assembly of NPs in mesoscale and complex aggregation patterns assisted by the wetting and the drying of complex fluids (suspensions of NPs, NPs/biopolymers mixed solutions) on homogeneous and heterogeneous molecular surfaces was studied. This issue is important, both for understanding fundamental processes of self-organization, and for generating new functional mesostructures. The

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34

Cheng, Kun. "Deformable models for adaptive radiotherapy planning." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/22893.

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Radiotherapy is the most widely used treatment for cancer, with 4 out of 10 cancer patients receiving radiotherapy as part of their treatment. The delineation of gross tumour volume (GTV) is crucial in the treatment of radiotherapy. An automatic contouring system would be beneficial in radiotherapy planning in order to generate objective, accurate and reproducible GTV contours. Image guided radiotherapy (IGRT) acquires patient images just before treatment delivery to allow any necessary positional correction. Consequently, real-time contouring system provides an opportunity to adopt radiothera

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35

Spadafora, Evan. "Etude par microscopie à force atomique en mode non contact et microscopie à sonde de Kelvin, de matériaux modèles pour le photovoltaïque organique." Phd thesis, Université de Grenoble, 2011. http://tel.archives-ouvertes.fr/tel-00647312.

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La nanostructure et les propriétés électroniques de matériaux modèles pour le photovoltaïque organique, ont été étudiées en utilisant la Microscopie à Force Atomique en mode non contact sous ultra-vide (NC-AFM) et la Microscopie à sonde de Kelvin (KPFM). En utilisant le mode modulation d'amplitude (AM-KPFM), le potentiel de surface photo- généré dans des mélanges donneur-accepteur présentant une ségrégation de phase optimale a pu être visualisé à l'échelle du nanomètre. Afin de préciser la nature des forces mises en jeu dans le processus d'imagerie KPFM, des oligomères π-conjugués auto-assembl

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Collins, E. C. J. "In vivo models for elucidation of role of MLL-AF9 chromosomal translocations in leukaemia." Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597866.

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Chromosomal translocations involving the <i>MLL</i> and <i>AF9</i> genes in human acute myeloid leukaemia were investigated using two complementary <i>in vivo</i> models. <i>LoxP</i> sites were introduced into the murine <i>Mll</i> and <i>Af9</i> genes by homologous recombination in embryonic stem (ES) cells, at positions corresponding to the breakpoints observed in human patients. Generation of <i>de novo </i>inter-chromosomal recombination events was evaluated by transient expression of Cre recombinase in doubly transfected ES cells. The presence and correct expression of the expected fusion

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Vogel, Alexander, Jörg Nikolaus, Katrin Weise, et al. "Interaction of the human N-Ras protein with lipid raft model membranes of varying degrees of complexity." Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-191006.

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Ternary lipid mixtures composed of cholesterol, saturated (frequently with sphingosine backbone), and unsaturated phospholipids show stable phase separation and are often used as model systems of lipid rafts. Yet, their ability to reproduce raft properties and function is still debated. We investigated the properties and functional aspects of three lipid raft model systems of varying degrees of biological relevance – PSM/POPC/Chol, DPPC/POPC/Chol, and DPPC/DOPC/Chol – using 2H solidstate nuclear magnetic resonance (NMR) spectroscopy, fluorescence microscopy, and atomic force microscopy. While

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38

Ury-Thiery, Vicky. "Agrégation in vitro de la protéine amyloïde Tau et étude de son impact sur des modèles membranaires par différentes méthodes biophysiques." Electronic Thesis or Diss., Bordeaux, 2024. http://www.theses.fr/2024BORD0440.

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Les maladies neurodégénératives, telles que les maladies d'Alzheimer et de Parkinson, affectent les fonctions cognitives et motrices. Elles se caractérisent par une perte progressive de neurones, sans possibilité de régénération. Avec le vieillissement de la population, ces pathologies, principalement liées à l'âge, représentent un enjeu sociétal majeur. L'absence de diagnostic précoce, de traitements efficaces et la méconnaissance des mécanismes en jeu soulignent la nécessité d'en approfondir la compréhension. Les patients atteints de ces maladies présentent des accumulations de protéines ano

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Huang, Chia-Pin John. "From the triple helix model (THM) to an actor flow model (AFM) : two case studies on the co-creative evolutionary relationship between universities, industry, the government, and a research institute in Taiwan." Thesis, University of Bath, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600723.

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The need for collaboration among different institutional actors including, universities, industry and governments, in national innovation systems, has been championed by the creators of the Triple Helix Model (e.g., Etzkowitz and Leydesdorff, 1995). However, these authors played down the importance of research institutes in these interactions during the evolution of innovation. Moreover, although under the THM it is accepted that there are flows of resources between actors, this has yet to be comprehensively conceptualised. To address these issues, in this research the THM is extended to a mod

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Wilson, Diane Easter. "A model curriculum for an associate of science in computer science, based on the ACM model, AACJC and CSAB guidelines." Virtual Press, 1991. http://liblink.bsu.edu/uhtbin/catkey/770947.

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This thesis argues that an AS model in computer science needs to be independent of a BS model because their student populations are distinct. The first two years of a BS model cannot be successfully copied in the AS environment. The AS model curriculum must begin at a different level while also providing competencies comparable to those in the first two years of a BS curriculum.Three questions had to be addressed before an AS model could be formulated. 1) What is an AS in computer science? Specific attention was given to the AA, AAS, BA and BS degrees, along with computer engineering, informat

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Lacroix, Loïc. "Mécanismes de corrosion localisée de l'alliage d'aluminium 2024 : apport de la microscopie à force atomique (AFM) couplée au mode Kelvin (KFM) et des alliages modèles." Phd thesis, Toulouse, INPT, 2008. http://oatao.univ-toulouse.fr/7821/1/lacroix.pdf.

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L'alliage 2024 (Al-Cu-Mg) est, dans le contexte de l'allègement de structure, encore largement utilisé par l'industrie aéronautique. Sa microstructure le rend sensible à la corrosion localisée (corrosion par piqûres, corrosion feuilletante et intergranulaire). Parmi les paramètres microstructuraux, les particules intermétalliques, et notamment les particules de phase S-Al2CuMg, sont dans de nombreux cas un facteur d'endommagement. Ce travail de thèse est donc centré sur leur réactivité ainsi que sur l'apport de techniques locales à cette étude. Dans ce travail, une étude multianalytique a été

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Lacroix, Loïc Baret-Blanc Christine Ressier Laurence. "Mécanismes de corrosion localisée de l'alliage d'aluminium 2024 apport de la microscopie à force atomique (AFM) couplée au mode Kelvin (KFM) et des alliages modèles /." Toulouse : INP Toulouse, 2009. http://ethesis.inp-toulouse.fr/archive/00000842.

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Amrous, Ania. "Etude d'auto-assemblages moléculaires sur surfaces isolantes par microscopie à force atomique en mode non-contact sous ultravide à température ambiante." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4368.

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Dans ce rapport de thèse, nous présentons les résultats obtenus avec la croissance d'assemblages supramoléculaires hautement cristallins et stables à température ambiante sur des surfaces isolantes d'halogénures d'alcalins. L'objectif de cette étude est de caractériser structurellement ces réseaux auto-assemblés et de mettre en évidence l'ensemble des forces d'interaction mises en œuvre dans les processus de croissance et de diffusion, en combinant la microscopie à force atomique en mode non contact (nc-AFM) sous ultravide et des calculs théoriques basés sur la théorie de la fonctionnelle de l

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Taccad, Caesar C. "A model of contract administration for the Armed Forces of the Philippines (AFP) modernization program." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 1999. http://handle.dtic.mil/100.2/ADA374091.

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Thesis (M.S. in Management) Naval Postgraduate School, December 1999.<br>"December 1999". Thesis advisor(s): David V. Lamm. David A. Smith. Includes bibliographical references (p. 115-117). Also available online.

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Myklatun, Ahne. "Production and Application of Micronsized Polysaccharide Particles - Studying Perturbation of a Model Mucus Barrier with Total Internal Reflection Fluorescence (TIRF) Microscopy and Atomic Force Microscopy (AFM) Indentation." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for fysikk, 2011. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-13742.

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The overall aim of this project was to produce homogeneously sized polysaccharide microparticles and apply these and similar sized particles as probes for investigation of mucin layers as a model for a biological barrier. Small polysaccharide particles have many applications, e.g. within the medical field of drug delivery. In this study a microfluidic system was developed to produce alginate beads, which can be used in drug delivery systems. Different designs, continuous phases and concentrations were tested in order to find an optimal system. Beads in the size range of 10 µm were produce

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Parkin, John D. "Microcantilevers : calibration of their spring constants and use as ultrasensitive probes of adsorbed mass." Thesis, University of St Andrews, 2013. http://hdl.handle.net/10023/3608.

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The dynamic properties of several rectangular and V-shaped microcantilevers were investigated. Particular attention was paid to the higher flexural eigenmodes of oscillation. The potential of the higher flexural modes was demonstrated through the use of cantilevers as standalone sensors for adsorbed mass. The mass adsorbed on the surface of a cantilever was in the form of a homogeneous water layer measured as a function of relative humidity. The minimum detectable water layer thicknesses were 13.7 Å, 3.2 Å, 1.1 Å, and 0.7 Å for the first four modes of a rectangular cantilever, clearly demonstr

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Vogel, Alexander, Jörg Nikolaus, Katrin Weise, et al. "Interaction of the human N-Ras protein with lipid raft model membranes of varying degrees of complexity." de Gruyter, 2014. https://ul.qucosa.de/id/qucosa%3A14050.

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Ternary lipid mixtures composed of cholesterol, saturated (frequently with sphingosine backbone), and unsaturated phospholipids show stable phase separation and are often used as model systems of lipid rafts. Yet, their ability to reproduce raft properties and function is still debated. We investigated the properties and functional aspects of three lipid raft model systems of varying degrees of biological relevance – PSM/POPC/Chol, DPPC/POPC/Chol, and DPPC/DOPC/Chol – using 2H solidstate nuclear magnetic resonance (NMR) spectroscopy, fluorescence microscopy, and atomic force microscopy. While

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Demianyk, Bryan C. P. "Development of agent-based models for healthcare: applications and critique." IEEE, 2010. http://hdl.handle.net/1993/31049.

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Agent-based modeling (ABM) is a modeling and simulation paradigm well-suited to social systems where agents interact and have some degree of autonomy. In their most basic sense, ABMs consist of agents (generally, individuals) interacting in an environment according to a set of behavioural rules. The foundational premise and the conceptual depth of ABM is that simple rules of individual behaviour will aggregate to illuminate complex and/or emergent group-level phenomena that are not specifically encoded by the modeler and that cannot be predicted or explained by the agent-level rules. In essen

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Horne, Jimmy D. Jr. "Modeling optical turbulence with COAMPS during two observation periods at Vandenberg AFB." Thesis, Monterey, California. Naval Postgraduate School, 2004. http://hdl.handle.net/10945/1671.

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Approved for public release, distribution is unlimited<br>The objective of this thesis is to investigate the forecastability of optical turbulence using the U.S. Navy's Coupled Ocean Atmosphere Mesoscale Prediction System (COAMPS). First, a detailed synoptic study was performed over the Eastern Pacific region for observation periods in October 2001 and March 2002 to focus on mesoscale features affecting Vandenberg AFB. Second, a modified version of COAMPS version 2.0.16 model output was evaluated to ensure reasonable modeling of the mesoscale. Next, temperature and dewpoint temperature vertica

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Amrous, Ania. "Etude d'auto-assemblages moléculaires sur surfaces isolantes par microscopie à force atomique en mode non-contact sous ultravide à température ambiante." Electronic Thesis or Diss., Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4368.

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Dans ce rapport de thèse, nous présentons les résultats obtenus avec la croissance d'assemblages supramoléculaires hautement cristallins et stables à température ambiante sur des surfaces isolantes d'halogénures d'alcalins. L'objectif de cette étude est de caractériser structurellement ces réseaux auto-assemblés et de mettre en évidence l'ensemble des forces d'interaction mises en œuvre dans les processus de croissance et de diffusion, en combinant la microscopie à force atomique en mode non contact (nc-AFM) sous ultravide et des calculs théoriques basés sur la théorie de la fonctionnelle de l

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