Log in

Relevant bibliographies by topics / AgrC / Journal articles

To see the other types of publications on this topic, follow the link: AgrC.

Journal articles on the topic 'AgrC'

Author: Grafiati

Published: 6 September 2023

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'AgrC.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Yu, Tao, Xiaojie Jiang, Xiaobo Xu, et al. "Cross-Phosphorylation between AgrC Histidine Kinase and the Noncognate Response Regulator Lmo1172 in Listeria monocytogenes under Benzalkonium Chloride Stress." Microorganisms 12, no. 2 (2024): 392. http://dx.doi.org/10.3390/microorganisms12020392.

Full text

Abstract:

Benzalkonium chloride (BC) is widely used for disinfection in the food industry. However, Listeria monocytogenes strains with resistance to BC have been reported recently. In L. monocytogenes, the Agr communication system consists of a membrane-bound peptidase AgrB, a precursor peptide AgrD, a histidine kinase (HK) AgrC, and a response regulator (RR) AgrA. Our previous study showed that the agr genes are significantly upregulated by BC adaptation. This study aimed to investigate the role of the Agr system in BC resistance in L. monocytogenes. Our results showed that the Agr system was involved

APA, Harvard, Vancouver, ISO, and other styles

2

Zhang, Linsheng, and Guangyong Ji. "Identification of a Staphylococcal AgrB Segment(s) Responsible for Group-Specific Processing of AgrD by Gene Swapping." Journal of Bacteriology 186, no. 20 (2004): 6706–13. http://dx.doi.org/10.1128/jb.186.20.6706-6713.2004.

Full text

Abstract:

ABSTRACT The four gene products of the accessory gene regulator (agr) P2 operon of Staphylococcus aureus assemble a quorum-sensing system: AgrA and AgrC resemble a two-component signal transduction system, and AgrB and AgrD are required to produce an autoinducing peptide. Upon activation, this quorum-sensing system positively regulates the transcription of the P2 operon as well as the P3 operon, whose transcript, RNAIII, regulates the expression of virulence genes. Four groups of S. aureus have been identified based on the agr sequences and the group-specific interaction between the autoinduci

APA, Harvard, Vancouver, ISO, and other styles

3

Zhu, Yan-Yan, Qiong Jin, Zhao-Jie Wang, et al. "Tripterhyponoid A from Tripterygium hypoglaucum Inhibiting MRSA by Multiple Mechanisms." Molecules 30, no. 12 (2025): 2539. https://doi.org/10.3390/molecules30122539.

Full text

Abstract:

The emergence of methicillin-resistant Staphylococcus aureus (MRSA) and its biofilm-forming ability underscore the limitations of current antibiotics. In this study, a new compound named tripterhyponoid A was found to effectively combat MRSA, with an MIC of 2.0 μg/mL. It inhibited biofilm formation by downregulating genes related to the quorum sensing (QS) pathway (sarA, agrA, agrB, agrC, agrD, and hld) and eradicated mature biofilms. Furthermore, it induced DNA damage by binding to bacterial DNA, enhancing its efficiency against MRSA. Therefore, its anti-MRSA properties with multiple mechanis

APA, Harvard, Vancouver, ISO, and other styles

4

Qian, Lijuan, Yuxin He, Wenzhe Lian, et al. "AgrC biotinylation inhibits Staphylococcus aureus infection." PLOS ONE 20, no. 4 (2025): e0318695. https://doi.org/10.1371/journal.pone.0318695.

Full text

Abstract:

Staphylococcus aureus (S. aureus) is a leading cause of nosocomial infections, particularly among antibiotic-resistant strains. S. aureus virulence is governed by the accessory gene regulator (Agr) quorum sensing (QS) system, which relies on AgrC, a two-component histidine kinase, to detect secreted auto-inducing peptides (AIPs). Emerging evidence highlights the potential of inhibiting the interaction between AgrC and AIPs as a promising therapeutic strategy. Given the limited clinic methods in inhibiting AgrC, we hereby report a novel method utilizing TurboID, an engineered biotin ligase, to

APA, Harvard, Vancouver, ISO, and other styles

5

Niyigaba, Jean, Jessica Ya Sun, Daiyan Peng, and Clemence Uwimbabazi. "Agriculture and Green Economy for Environmental Kuznets Curve Adoption in Developing Countries: Insights from Rwanda." Sustainability 12, no. 24 (2020): 10381. http://dx.doi.org/10.3390/su122410381.

Full text

Abstract:

Development and climate change are crucial global concerns with significant contrasts between developed and developing nations. Contrary to several developing countries, Rwanda opted for a green growth policy pathway while struggling with its economic emergence through the alternative green sectors, including agriculture. No research has yet been conducted on the choice’s performance on emission sequestration or the country’s income, allowing the formulation of strategies accordingly. The environmental Kuznets curve (EKC), mostly adopted by developed countries, is applied for the Rwandese scen

APA, Harvard, Vancouver, ISO, and other styles

6

Rieu, Aurélie, Stéphanie Weidmann, Dominique Garmyn, Pascal Piveteau, and Jean Guzzo. "agr System of Listeria monocytogenes EGD-e: Role in Adherence and Differential Expression Pattern." Applied and Environmental Microbiology 73, no. 19 (2007): 6125–33. http://dx.doi.org/10.1128/aem.00608-07.

Full text

Abstract:

ABSTRACT In this study, we investigated the agrBDCA operon in the pathogenic bacterium Listeria monocytogenes EGD-e. In-frame deletion of agrA and agrD resulted in an altered adherence and biofilm formation on abiotic surfaces, suggesting the involvement of the agr system of L. monocytogenes during the early stages of biofilm formation. Real-time PCR experiments indicated that the transcript levels of agrBDCA depended on the stage of biofilm development, since the levels were lower after the initial attachment period than during biofilm growth, whereas transcription during planktonic growth wa

APA, Harvard, Vancouver, ISO, and other styles

7

Lade, Harshad, Sung Hee Chung, Yeonhee Lee, et al. "Thymol Reduces agr-Mediated Virulence Factor Phenol-Soluble Modulin Production in Staphylococcus aureus." BioMed Research International 2022 (May 9, 2022): 1–14. http://dx.doi.org/10.1155/2022/8221622.

Full text

Abstract:

Staphylococcus aureus is a major human bacterial pathogen that carries a large number of virulence factors. Many virulence factors of S. aureus are regulated by the accessory gene regulator (agr) quorum-sensing system. Phenol-soluble modulins (PSMs) are one of the agr-mediated virulence determinants known to play a significant role in S. aureus pathogenesis. In the present study, the efficacy of thymol to inhibit PSM production including δ-toxin in S. aureus was explored. We employed liquid chromatography–mass spectrometry (LC–MS) to quantify the PSMsα1–PSMα4, PSMβ1 and PSMβ2, and δ-toxin prod

APA, Harvard, Vancouver, ISO, and other styles

8

McNamara, Peter J., and John J. Iandolo. "Genetic Instability of the Global Regulator agrExplains the Phenotype of the xpr Mutation inStaphylococcus aureus KSI9051." Journal of Bacteriology 180, no. 10 (1998): 2609–15. http://dx.doi.org/10.1128/jb.180.10.2609-2615.1998.

Full text

Abstract:

ABSTRACT Staphylococcus aureus KSI9051 has a complex mutation that was associated with the aberrant expression of cell surface and extracellular proteins (M. S. Smeltzer, M. E. Hart, and J. J. Iandolo, J. Bacteriol. 61:919–925, 1993). This mutation was named xpr, although no specific gene was identified. Here this mutation is referred to as Δ1058::Tn551. In this study, we show that in strain KSI9051, the Δ1058::Tn551 mutation occurred coincidentally with a frameshift in agrC that is expected to truncate the sensor component of the known staphylococcal global regulatory locus agr. Remarkably, p

APA, Harvard, Vancouver, ISO, and other styles

9

van Leeuwen, Willem, Wendy van Nieuwenhuizen, Christel Gijzen, Henri Verbrugh, and Alex van Belkum. "Population Studies of Methicillin-Resistant and -Sensitive Staphylococcus aureus Strains Reveal a Lack of Variability in the agrD Gene, Encoding a Staphylococcal Autoinducer Peptide." Journal of Bacteriology 182, no. 20 (2000): 5721–29. http://dx.doi.org/10.1128/jb.182.20.5721-5729.2000.

Full text

Abstract:

ABSTRACT The virulence of Staphylococcus aureus is controlled by the accessory gene regulator (agr) system, including an extracellular inducer encoded by agrD. Variableagr PCR restriction fragment length polymorphism (RFLP) patterns of unique S. aureus strains (n = 192) were determined for a region comprising agrD and parts of the neighboring agrC and agrB genes. Twelve unique RFLP patterns were identified among S. aureusstrains in general; these patterns were further specified by sequencing. All sequences could be catalogued in the three currentagr groups. A major proportion of the S. aureuss

APA, Harvard, Vancouver, ISO, and other styles

10

Sung, Julia M. L., Peter D. Chantler, and David H. Lloyd. "Accessory Gene Regulator Locus of Staphylococcus intermedius." Infection and Immunity 74, no. 5 (2006): 2947–56. http://dx.doi.org/10.1128/iai.74.5.2947-2956.2006.

Full text

Abstract:

ABSTRACT The accessory gene regulator (agr) locus, a candidate system for the regulation of the production of virulence factors in Staphylococcus intermedius, has been characterized. Using PCR-based genome walking, we have obtained the first complete sequence (3,436 bp) of the accessory gene regulator (agr) gene in this organism. Sequence analysis of the agr gene has identified five open reading frames (ORFs), agrB, agrD, agrC, agrA, and hld. The translated ORF contained amino acid motifs characteristic of the response regulator and histidine protein kinase signal transducer of the classic two

APA, Harvard, Vancouver, ISO, and other styles

11

Xie, Qian, Mareike M. Wiedmann, Aishan Zhao, et al. "Discovery of quorum quenchers targeting the membrane-embedded sensor domain of the Staphylococcus aureus receptor histidine kinase, AgrC." Chemical Communications 56, no. 76 (2020): 11223–26. http://dx.doi.org/10.1039/d0cc04873a.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Somerville, Greg A., Stephen B. Beres, J. Ross Fitzgerald, et al. "In Vitro Serial Passage of Staphylococcus aureus: Changes in Physiology, Virulence Factor Production, and agr Nucleotide Sequence." Journal of Bacteriology 184, no. 5 (2002): 1430–37. http://dx.doi.org/10.1128/jb.184.5.1430-1437.2002.

Full text

Abstract:

ABSTRACT Recently, we observed that Staphylococcus aureus strains newly isolated from patients had twofold-higher aconitase activity than a strain passaged extensively in vitro, leading us to hypothesize that aconitase specific activity decreases over time during in vitro passage. To test this hypothesis, a strain recovered from a patient with toxic shock syndrome was serially passaged for 6 weeks, and the aconitase activity was measured. Aconitase specific activity decreased 38% (P < 0.001) by the sixth week in culture. During serial passage, S. aureus existed as a heterogeneous population

APA, Harvard, Vancouver, ISO, and other styles

13

Srivastava, S. K., K. Rajasree, A. Fasim, G. Arakere, and B. Gopal. "Influence of the AgrC-AgrA Complex on the Response Time of Staphylococcus aureus Quorum Sensing." Journal of Bacteriology 196, no. 15 (2014): 2876–88. http://dx.doi.org/10.1128/jb.01530-14.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Wang, Li, Lin Qiao, Aike Li, et al. "Integrative Multiomics Analysis of the Heat Stress Response of Enterococcus faecium." Biomolecules 13, no. 3 (2023): 437. http://dx.doi.org/10.3390/biom13030437.

Full text

Abstract:

A continuous heat-adaptation test was conducted for one Enterococcus faecium (E. faecium) strain wild-type (WT) RS047 to obtain a high-temperature-resistant strain. After domestication, the strain was screened with a significantly higher ability of heat resistance. which is named RS047-wl. Then a multi-omics analysis of transcriptomics and metabolomics was used to analyze the mechanism of the heat resistance of the mutant. A total of 98 differentially expressed genes (DEGs) and 115 differential metabolites covering multiple metabolic processes were detected in the mutant, which indicated that

APA, Harvard, Vancouver, ISO, and other styles

15

Wang, Lina, Chunshan Quan, Yongbin Xu, Xihui Li, Xiaojing Qu, and Shengdi Fan. "Construction of AgrC Proteoliposomes by Detergent-Mediated Method." Acta Chimica Sinica 72, no. 2 (2014): 233. http://dx.doi.org/10.6023/a13111123.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Jordani, Bárbara, Francisco Roger Carneiro Ribeiro, Valéria Costa de Oliveira, and Rodrigo Cesar Pierozan. "Efeito da saturação do agregado graúdo reciclado na resistência mecânica e durabilidade do concreto." Revista de Arquitetura IMED 13, no. 1 (2024): 70. https://doi.org/10.18256/2318-1109.2024.v13i1.5067.

Full text

Abstract:

A incorporação de resíduos de concreto na produção de novos concretos revela-se como uma abordagem sustentável na construção civil. No entanto, é essencial o estudo das propriedades mecânicas e de durabilidade do concreto produzido com este resíduo, garantindo a segurança das edificações. Este trabalho investiga o comportamento mecânico, a resistividade elétrica e a absorção de água por capilaridade em concretos convencionais, sob diferentes relações água/aglomerante, produzidos com agregados graúdos reciclados de concreto (AGRC) secos e úmidos, curados em condições de baixa e alta umidade rel

APA, Harvard, Vancouver, ISO, and other styles

17

Allocca, V., F. Manna, and P. De Vita. "Estimating annual groundwater recharge coefficient for karst aquifers of the southern Apennines (Italy)." Hydrology and Earth System Sciences 18, no. 2 (2014): 803–17. http://dx.doi.org/10.5194/hess-18-803-2014.

Full text

Abstract:

Abstract. To assess the mean annual groundwater recharge of the karst aquifers in the southern Apennines (Italy), the estimation of the mean annual groundwater recharge coefficient (AGRC) was conducted by means of an integrated approach based on hydrogeological, hydrological, geomorphological, land use and soil cover analyses. Starting from the hydrological budget equation, the coefficient was conceived as the ratio between the net groundwater outflow and the precipitation minus actual evapotranspiration (P − ETR) for a karst aquifer. A large part of the southern Apennines, which is covered by

APA, Harvard, Vancouver, ISO, and other styles

18

Jarraud, S., G. J. Lyon, A. M. S. Figueiredo, et al. "Exfoliatin-Producing Strains Define a Fourthagr Specificity Group in Staphylococcus aureus." Journal of Bacteriology 182, no. 22 (2000): 6517–22. http://dx.doi.org/10.1128/jb.182.22.6517-6522.2000.

Full text

Abstract:

ABSTRACT The staphylococcal virulon is activated by the density-sensingagr system, which is autoinduced by a short peptide (autoinducing peptide [AIP]) processed from a propeptide encoded byagrD. A central segment of the agr locus, consisting of the C-terminal two-thirds of AgrB (the putative processing enzyme), AgrD, and the N-terminal half of AgrC (the receptor), shows striking interstrain variation. This finding has led to the division of Staphylococcus aureus isolates into three different agr specificity groups and to the division of non-aureus staphylococci into a number of others. The AI

APA, Harvard, Vancouver, ISO, and other styles

19

Zhang, Liying, Chunshan Quan, Xuning Zhang, Wen Xiong, and Shengdi Fan. "Proteoliposome‐based model for screening inhibitors targeting histidine kinase AgrC." Chemical Biology & Drug Design 93, no. 5 (2019): 712–23. http://dx.doi.org/10.1111/cbdd.13497.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Steiner, Elisabeth, Jamie Scott, Nigel P. Minton, and Klaus Winzer. "AnagrQuorum Sensing System That Regulates Granulose Formation and Sporulation in Clostridium acetobutylicum." Applied and Environmental Microbiology 78, no. 4 (2011): 1113–22. http://dx.doi.org/10.1128/aem.06376-11.

Full text

Abstract:

ABSTRACTThe Gram-positive, anaerobic, endospore-forming bacteriumClostridium acetobutylicumhas considerable biotechnological potential due to its ability to produce solvents as fermentation products, in particular the biofuel butanol. Its genome contains a putativeagrlocus,agrBDCA, known in staphylococci to constitute a cyclic peptide-based quorum sensing system. In staphylococci,agrBDis required for the generation of a peptide signal that, upon extracellular accumulation, is sensed by anagrCA-encoded two-component system. Using ClosTron technology,agrB,agrC, andagrAmutants ofC. acetobutylicum

APA, Harvard, Vancouver, ISO, and other styles

21

George Cisar, Elizabeth A., Edward Geisinger, Tom W. Muir, and Richard P. Novick. "Symmetric signalling within asymmetric dimers of theStaphylococcus aureusreceptor histidine kinase AgrC." Molecular Microbiology 74, no. 1 (2009): 44–57. http://dx.doi.org/10.1111/j.1365-2958.2009.06849.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Wang, Lina, Chunshan Quan, Wen Xiong, Xiaojing Qu, Shengdi Fan, and Wenzhong Hu. "New insight into transmembrane topology of Staphylococcus aureus histidine kinase AgrC." Biochimica et Biophysica Acta (BBA) - Biomembranes 1838, no. 3 (2014): 988–93. http://dx.doi.org/10.1016/j.bbamem.2013.12.006.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Geisinger, Edward, Elizabeth A. George, John Chen, Tom W. Muir, and Richard P. Novick. "Identification of ligand specificity determinants in AgrC, theStaphylococcus aureusquorum-sensing receptor." Journal of Biological Chemistry 287, no. 22 (2012): 18588. http://dx.doi.org/10.1074/jbc.a112.710227.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Geisinger, Edward, Elizabeth A. George, Tom W. Muir, and Richard P. Novick. "Identification of Ligand Specificity Determinants in AgrC, theStaphylococcus aureusQuorum-sensing Receptor." Journal of Biological Chemistry 283, no. 14 (2008): 8930–38. http://dx.doi.org/10.1074/jbc.m710227200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Li, Wei, Xiaoyu Ma, Yumin Chen, et al. "Random Fuzzy Granular Decision Tree." Mathematical Problems in Engineering 2021 (June 9, 2021): 1–17. http://dx.doi.org/10.1155/2021/5578682.

Full text

Abstract:

In this study, the classification problem is solved from the view of granular computing. That is, the classification problem is equivalently transformed into the fuzzy granular space to solve. Most classification algorithms are only adopted to handle numerical data; random fuzzy granular decision tree (RFGDT) can handle not only numerical data but also nonnumerical data like information granules. Measures can be taken in four ways as follows. First, an adaptive global random clustering (AGRC) algorithm is proposed, which can adaptively find the optimal cluster centers and maximize the ratio of

APA, Harvard, Vancouver, ISO, and other styles

26

Wang, Boyuan, Aishan Zhao, Qian Xie, et al. "Functional Plasticity of the AgrC Receptor Histidine Kinase Required for Staphylococcal Virulence." Cell Chemical Biology 24, no. 1 (2017): 76–86. http://dx.doi.org/10.1016/j.chembiol.2016.12.008.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

AL-Sabaawy, Abeer Mahmood, Enas Abdul-muniem., AL-Layla, and Omar Ibrahim AL-Sabaawy. "Detection of bacterial infection of the eye chalazion in Mosul City." Science Archives 03, no. 04 (2022): 240–46. http://dx.doi.org/10.47587/sa.2022.3401.

Full text

Abstract:

Chalazion is a common infection of the meibomian gland in all ages’ eyelids. The current study sought to isolate and identify bacteria linked with chalazion in patients hospitalized to Mosul hospitals between 10/1/2021 and 1/3/2022. Samples were obtained using swabs soaked in the transport media (amies), and bacteria were identified using traditional methods with API20E. Vitek-2 and molecular approaches based on the 16 S rRNA gene verified the species-level diagnosis. Using BLAST software, the nitrogen base sequences were determined and compared to those of the NCBI. The results showed that St

APA, Harvard, Vancouver, ISO, and other styles

28

Lina, Gerard, Sophie Jarraud, Guangyong Ji, et al. "Transmembrane topology and histidine protein kinase activity of AgrC, theagrsignal receptor inStaphylococcus aureus." Molecular Microbiology 28, no. 3 (1998): 655–62. http://dx.doi.org/10.1046/j.1365-2958.1998.00830.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Green, Macauley J., Ewan J. Murray, Paul Williams, Amir M. Ghaemmaghami, Jonathan W. Aylott, and Philip M. Williams. "Modelled-Microgravity Reduces Virulence Factor Production in Staphylococcus aureus through Downregulation of agr-Dependent Quorum Sensing." International Journal of Molecular Sciences 24, no. 21 (2023): 15997. http://dx.doi.org/10.3390/ijms242115997.

Full text

Abstract:

Bacterial contamination during space missions is problematic for human health and damages filters and other vital support systems. Staphylococcus aureus is both a human commensal and an opportunistic pathogen that colonizes human tissues and causes acute and chronic infections. Virulence and colonization factors are positively and negatively regulated, respectively, by bacterial cell-to-cell communication (quorum sensing) via the agr (accessory gene regulator) system. When cultured under low-shear modelled microgravity conditions (LSMMG), S. aureus has been reported to maintain a colonization

APA, Harvard, Vancouver, ISO, and other styles

30

Qin, Xiang, Kavindra V. Singh, George M. Weinstock, and Barbara E. Murray. "Effects of Enterococcus faecalis fsrGenes on Production of Gelatinase and a Serine Protease and Virulence." Infection and Immunity 68, no. 5 (2000): 2579–86. http://dx.doi.org/10.1128/iai.68.5.2579-2586.2000.

Full text

Abstract:

ABSTRACT Three agr-like genes (fsrA,fsrB, and fsrC, for Enterococcus faecalis regulator) were found upstream of the previously reported gelatinase gene (gelE) and a downstream putative serine protease gene (sprE; accession number Z12296 ) ofEnterococcus faecalis OG1RF. The deduced amino acid sequence of fsrA shows 26% identity and 38% similarity toStaphylococcus aureus AgrA (the response regulator of the accessory gene regulator system in the agr locus), FsrB shows 23% identity and 41% similarity to S. aureus AgrB, and FsrC shows 23% identity and 36% similarity to S. aureus AgrC (the sensor tr

APA, Harvard, Vancouver, ISO, and other styles

31

Oliveira, Edenis Cesar. "Influência da variável ambiental no processo de escolha dos fornecedores: Um Estudo em Agroindústrias da Microrregião de Assis-SP." Revista Produção e Desenvolvimento 2, no. 2 (2016): 77–100. http://dx.doi.org/10.32358/rpd.2016.v2.117.

Full text

Abstract:

The global market characterized by competition, has demanded of new placements organizations, particularly as to how implement and develop relations with its trading partners. The Supply Chain Management emerges as a tool that provides organizations with the most effective management of the consequences of these relations. The incorporation of environmental issues in the organizational context reflected directly across chain. Organizations began to consider sustainability as a major factor in relations with its stakeholders, justifying the emergence of Sustainable Management of Supply Chain. T

APA, Harvard, Vancouver, ISO, and other styles

32

Xiang, Bingquan, Yujie Lei, Ya Chen, et al. "Mechanistic study on the inhibition of Staphylococcus epidermidis biofilm by agrC-specific binding polypeptide." Annals of Translational Medicine 8, no. 6 (2020): 337. http://dx.doi.org/10.21037/atm.2020.02.84.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Wang, Lina, Chunshan Quan, Baoquan Liu, et al. "Functional Reconstitution of Staphylococcus aureus Truncated AgrC Histidine Kinase in a Model Membrane System." PLoS ONE 8, no. 11 (2013): e80400. http://dx.doi.org/10.1371/journal.pone.0080400.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Huang, Qian, Yihui Xie, Ziyu Yang, et al. "The cytoplasmic loops of AgrC contribute to the quorum-sensing activity of Staphylococcus aureus." Journal of Microbiology 59, no. 1 (2020): 92–100. http://dx.doi.org/10.1007/s12275-021-0274-x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Dmitrenko, Olga, Andrey Chaplin, Anna Balbutskaya, Tamara Pkhakadze, and Sergey Alkhovsky. "In Silico Genome-Scale Analysis of Molecular Mechanisms Contributing to the Development of a Persistent Infection with Methicillin-Resistant Staphylococcus aureus (MRSA) ST239." International Journal of Molecular Sciences 23, no. 24 (2022): 16086. http://dx.doi.org/10.3390/ijms232416086.

Full text

Abstract:

The increasing frequency of isolation of methicillin-resistant Staphylococcus aureus (MRSA) limits the chances for the effective antibacterial therapy of staphylococcal diseases and results in the development of persistent infection such as bacteremia and osteomyelitis. The aim of this study was to identify features of the MRSAST239 0943-1505-2016 (SA943) genome that contribute to the formation of both acute and chronic musculoskeletal infections. The analysis was performed using comparative genomics data of the dominant epidemic S. aureus lineages, namely ST1, ST8, ST30, ST36, and ST239. The

APA, Harvard, Vancouver, ISO, and other styles

36

Yang, Tian, Yftah Tal-Gan, Alexandra E. Paharik, Alexander R. Horswill, and Helen E. Blackwell. "Structure–Function Analyses of aStaphylococcus epidermidisAutoinducing Peptide Reveals Motifs Critical for AgrC-type Receptor Modulation." ACS Chemical Biology 11, no. 7 (2016): 1982–91. http://dx.doi.org/10.1021/acschembio.6b00120.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Chan, Weng C., Barry J. Coyle, and Paul Williams. "Virulence Regulation and Quorum Sensing in Staphylococcal Infections: Competitive AgrC Antagonists as Quorum Sensing Inhibitors§." Journal of Medicinal Chemistry 47, no. 19 (2004): 4633–41. http://dx.doi.org/10.1021/jm0400754.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Wang, Boyuan, Aishan Zhao, Richard P. Novick, and Tom W. Muir. "Activation and Inhibition of the Receptor Histidine Kinase AgrC Occurs through Opposite Helical Transduction Motions." Molecular Cell 53, no. 6 (2014): 929–40. http://dx.doi.org/10.1016/j.molcel.2014.02.029.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Hansen, Anna Mette, Pai Peng, Mara Baldry, et al. "Lactam hybrid analogues of solonamide B and autoinducing peptides as potent S. aureus AgrC antagonists." European Journal of Medicinal Chemistry 152 (May 2018): 370–76. http://dx.doi.org/10.1016/j.ejmech.2018.04.053.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Spiegel, Christopher, Stephan Josef Maria Steixner, and Débora C. Coraça-Huber. "Antibiofilm Activity of Omega-3 Fatty Acids and Its Influence on the Expression of Biofilm Formation Genes on Staphylococcus aureus." Antibiotics 11, no. 7 (2022): 932. http://dx.doi.org/10.3390/antibiotics11070932.

Full text

Abstract:

Background: Currently, 1–2% of all prosthetic joint surgeries are followed by an infection. These infections cause approximately 4% of deaths in the first year after surgery, while the 5-year mortality rate is up to 21%. Prosthetic joint infections are mainly caused by Staphylococcus aureus or Staphylococcus epidermis strains. Both species share the capability of biofilm formation and methicillin resistance. The formation of biofilm helps bacterial cells to withstand critical environmental conditions. Due to their tolerance against antibacterial substances, biofilms are a significant problem i

APA, Harvard, Vancouver, ISO, and other styles

41

Qazi, Saara, Barry Middleton, Siti Hanna Muharram, et al. "N-Acylhomoserine Lactones Antagonize Virulence Gene Expression and Quorum Sensing in Staphylococcus aureus." Infection and Immunity 74, no. 2 (2006): 910–19. http://dx.doi.org/10.1128/iai.74.2.910-919.2006.

Full text

Abstract:

ABSTRACT Many gram-negative bacteria employ N-acylhomoserine lactone (AHL)-mediated quorum sensing to control virulence. To determine whether gram-positive bacteria such as Staphylococcus aureus respond to AHLs, we used a growth-dependent lux reporter fusion. Exposure of S. aureus to different AHLs revealed that 3-oxo-substituted AHLs with C10 to C14 acyl chains inhibited light output and growth in a concentration-dependent manner, while short-chain AHLs had no effect. N-(3-Oxododecanoyl)-l-homoserine lactone (3-oxo-C12-HSL) inhibited the production of exotoxins and cell wall fibronectin-bindi

APA, Harvard, Vancouver, ISO, and other styles

42

Vasquez, Joseph K., and Helen E. Blackwell. "Simplified Autoinducing Peptide Mimetics with Single-Nanomolar Activity Against the Staphylococcus aureus AgrC Quorum Sensing Receptor." ACS Infectious Diseases 5, no. 4 (2019): 484–92. http://dx.doi.org/10.1021/acsinfecdis.9b00002.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Zorzet, A., J. M. Andersen, A. I. Nilsson, N. F. Moller, and D. I. Andersson. "Compensatory mutations in agrC partly restore fitness in vitro to peptide deformylase inhibitor-resistant Staphylococcus aureus." Journal of Antimicrobial Chemotherapy 67, no. 8 (2012): 1835–42. http://dx.doi.org/10.1093/jac/dks168.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Tal-Gan, Yftah, Monika Ivancic, Gabriel Cornilescu, Tian Yang, and Helen E. Blackwell. "Highly Stable, Amide-Bridged Autoinducing Peptide Analogues that Strongly Inhibit the AgrC Quorum Sensing Receptor inStaphylococcus aureus." Angewandte Chemie International Edition 55, no. 31 (2016): 8913–17. http://dx.doi.org/10.1002/anie.201602974.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Tal-Gan, Yftah, Monika Ivancic, Gabriel Cornilescu, Tian Yang, and Helen E. Blackwell. "Highly Stable, Amide-Bridged Autoinducing Peptide Analogues that Strongly Inhibit the AgrC Quorum Sensing Receptor inStaphylococcus aureus." Angewandte Chemie 128, no. 31 (2016): 9059–63. http://dx.doi.org/10.1002/ange.201602974.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Botelho, Ana M. N., Maiana O. C. Costa, Cristiana O. Beltrame, et al. "Complete Genome Sequence of the MRSA Isolate HC1335 from ST239 Lineage Displaying a Truncated AgrC Histidine Kinase Receptor." Genome Biology and Evolution 8, no. 10 (2016): 3187–92. http://dx.doi.org/10.1093/gbe/evw225.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Broderick, Adam H., Danielle M. Stacy, Yftah Tal-Gan, Michael J. Kratochvil, Helen E. Blackwell, and David M. Lynn. "Surface Coatings that Promote Rapid Release of Peptide-Based AgrC Inhibitors for Attenuation of Quorum Sensing inStaphylococcus aureus." Advanced Healthcare Materials 3, no. 1 (2013): 97–105. http://dx.doi.org/10.1002/adhm.201300119.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Wang, Boyuan, Aishan Zhao, Richard P. Novick, and Tom W. Muir. "Key driving forces in the biosynthesis of autoinducing peptides required for staphylococcal virulence." Proceedings of the National Academy of Sciences 112, no. 34 (2015): 10679–84. http://dx.doi.org/10.1073/pnas.1506030112.

Full text

Abstract:

Staphylococci produce autoinducing peptides (AIPs) as quorum-sensing signals that regulate virulence. These AIPs feature a thiolactone macrocycle that connects the peptide C terminus to the side chain of an internal cysteine. AIPs are processed from ribosomally synthesized precursors [accessory gene regulator D (AgrD)] through two proteolytic events. Formation of the thiolactone is coupled to the first of these and involves the activity of the integral membrane protease AgrB. This step is expected to be thermodynamically unfavorable, and therefore, it is unclear how AIP-producing bacteria prod

APA, Harvard, Vancouver, ISO, and other styles

49

Wang, Lina, Chunshan Quan, Baoquan Liu, et al. "Green Fluorescent Protein (GFP)-Based Overexpression Screening and Characterization of AgrC, a Receptor Protein of Quorum Sensing in Staphylococcus aureus." International Journal of Molecular Sciences 14, no. 9 (2013): 18470–87. http://dx.doi.org/10.3390/ijms140918470.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Liu, Jianan, Jinle Ma, Yingrui Wang, et al. "Synergistic Antibacterial Mechanism of Benzyl Isothiocyanate and Resveratrol Against Staphylococcus aureus Revealed by Transcriptomic Analysis and Their Application in Beef." Foods 14, no. 9 (2025): 1610. https://doi.org/10.3390/foods14091610.

Full text

Abstract:

This study aims to elucidate the synergistic antibacterial mechanism of benzyl isothiocyanate (BITC) and resveratrol (RES) on Staphylococcus aureus (S. aureus) at the transcriptional level. Compared with the individuals, the combination of BITC and RES (BITC_RES) reduced S. aureus growth, inhibited biofilm formation, and increased cell membrane disruption. The transcriptomic results showed that the BITC_RES group presented 245 and 1150 more DEGs than the BITC group and the RES group, respectively. In addition, some other key genes in the BITC_RES group, including serine protease (splA, splE),

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!