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Dissertations / Theses on the topic 'Airway (Medicine)'

Author: Grafiati

Published: 4 June 2021

Last updated: 31 July 2024

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1

Svensson, Holm Ann-Charlotte B. "Platelets and airway remodeling : Mechanisms involved in platelet-induced fibroblast and airway smooth muscle cell proliferation in vitro." Doctoral thesis, Linköpings universitet, Farmakologi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-61623.

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Airway remodeling is a contributing cause to the pathological structural changes, such as increased cell proliferation, observed in asthma. Platelets have been found in autopsy lungmaterial obtained from asthmatic patients and are well known to induce proliferation in vitro of a variety of cells. However, the role of platelets in airway remodeling is far from understood. This thesis aims to clarify the involvement of platelets in fibroblast and airway smooth muscle cell (ASMC) proliferation in vitro and to elucidate the importance of HA, FAK, eicosanoid and ROS dependent signaling. The results

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2

Noble, Peter Beresford. "Regulation of airway narrowing by dynamic and static mechanical loads." University of Western Australia. School of Biomedical and Chemical Sciences, 2006. http://theses.library.uwa.edu.au/adt-WU2006.0050.

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[Truncated abstract] The extent to which an airway narrows is strongly influenced by mechanical loads on airway smooth muscle (ASM). This thesis considers both dynamic and static mechanical loads. Dynamic load describes the time varying load on airways produced by oscillatory breathing movements. Static load is that present at a fixed lung volume ie. without breathing. In the intact lung static load principally comprises the pressure across the airway wall, that is transmural pressure (Ptm), and elastic after-load arising from distortion of airway and lung tissue by the narrowing airway. The e

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3

Lau, Justine Y. "Novel genes associated with airway smooth muscle proliferation in asthma." Connect to full text, 2008. http://hdl.handle.net/2123/5134.

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Thesis (Ph. D.)--University of Sydney, 2009.<br>Title from title screen (viewed Aug. 11, 2009) Submitted in fulfilment of the requirements for the degree of Doctor of Philosophy to the Discipline of Pharmacology, Faculty of Medicine. Degree awarded 2009; thesis submitted 2008. Includes bibliographical references. Also available in print form.

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4

Mohammadi, Hamed. "Cephalometric airway measurements in anterior open bite deformity." Thesis, [Hong Kong : Faculty of Dentistry], The University of Hong Kong, 1997. http://sunzi.lib.hku.hk/HKUTO/record/B3862820X.

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5

Grainge, Christopher. "Determinants of airway remodelling in asthma." Thesis, University of Southampton, 2010. https://eprints.soton.ac.uk/384164/.

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6

Fitch, Patrick Stephen. "A study of airway inflammation in childhood asthma." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326411.

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7

Pandya, Hitesh Champaklal. "Investigations of fetal human airway smooth muscle : potential mechanisms of abnormal airway wall modelling in chronic lung disease of preterm infants." Thesis, King's College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248390.

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8

Ip, Sau-man Mary. "A pathophysiologic study of airway inflammation in bronchiectasis." [Hong Kong : University of Hong Kong], 1991. http://sunzi.lib.hku.hk/hkuto/record.jsp?B13793895.

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9

Tang, Shu-sum. "Cephalometric airway measurements in class III skeletal deformity." Click to view the E-thesis via HKUTO, 2000. http://sunzi.lib.hku.hk/HKUTO/record/B38628065.

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10

葉秀文 and Sau-man Mary Ip. "A pathophysiologic study of airway inflammation in bronchiectasis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1991. http://hub.hku.hk/bib/B31981434.

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11

McKay, Anne. "The role of immune mediators in airway inflammation." Thesis, University of Glasgow, 2004. http://theses.gla.ac.uk/4828/.

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Asthma is a chronic inflammatory condition of the airways characterised by reversible airflow obstruction, airway hyper-responsiveness and inflammatory infiltrates in the airway walls containing eosinophils, T lymphocytes and mast cells. T helper (Th) lymphocyte subsets, defined by the cytokines they secrete, are thought to play a key role in the in the initiation and perpetuation of chronic airway inflammation. Th2 cells, producing interleukin (IL)-4, IL-5, IL-9 and IL-13, are thought to be of particular importance. In contrast, Thl cells producing interferon (IFN)-y may counteract the develo

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12

Wong, Fung-ping, and 黃鳳屏. "A retrospective study of tracheal morphometry in Chinese adults by computed tomography." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48273685.

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Objective: To determine the upper airway morphometry of Chinese adults by computed tomography. Study Design: This anatomical study consisted of radiological examination of Chinese adults’ upper airway and trachea using computed tomography and image analysis with the help of post-data capture processing software. Materials and Methods: A retrospective review of sixty-five Chinese adults who underwent computed tomography of head and neck region at a regional hospital in Hong Kong was conducted. Computed tomography performed by a Philips Gemini 16? PET/CTPhilips Gemini GXL 16 PET/CT S

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13

Wilkinson, Thomas Michael Alan. "The role of airway infection in chronic obstructive pulmonary disease." Thesis, Queen Mary, University of London, 2006. http://qmro.qmul.ac.uk/xmlui/handle/123456789/1897.

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This. thesis examines the role of respiratory bacterial and viral infection in the natural history of Chronic Obstructive Pulmonary Disease. The rationale for this study is basedu pon previous data demonstratingt hat airway bacterial colonisationi s common in stable COPD and that bacterial and viral pathogens are commonly detected at exacerbations. The methodsu sed have involved the careful characterisationa nd clinical follow up of a cohort of patients with moderate to severe COPD in the stable state and at exacerbation. Sampling of airway and systemic compartments enabled the detection of re

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14

Neumann, Peter. "Airway pressure release ventilation : a systematic experimental approach /." Uppsala, Sweden : Uppsala University : Distributed by Uppsala University Library, 2000. http://w3.ub.uu.se/diss/eng/abstract.cfm?ISBN=91-554-4723-6.

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15

Ratnawati, Ratnawati Prince of Wale Hospital Clinical School UNSW. "Exhaled nitric oxide in asthmatic airway inflammation." Awarded by:University of New South Wales. Prince of Wale Hospital Clinical School, 2006. http://handle.unsw.edu.au/1959.4/25729.

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Measuring the level of exhaled NO (eNO) in the breath is a new method to monitor airway inflammation in asthma and may have a role in the management of asthma. The hypotheses were that eNO will reflect the degree of inflammation in chronic asthma, and will indicate how anti- inflammatory therapy should be altered to improve asthma control. Three studies were performed to test the hypotheses. A cross sectional study was performed to define the normal range of eNO and to compare this range with those who have asthma or atopy. The second study was observational, to compare the level of eNO during

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16

Laing, Ingrid A. "Candidate gene approach to investigating airway inflammation and asthma /." Connect to this title, 2004. http://theses.library.uwa.edu.au/adt-WU2005.0097.

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17

Wang, Dong. "Regulation of anion secretion in human airway epithelial cells /." View abstract or full-text, 2009. http://library.ust.hk/cgi/db/thesis.pl?BIOL%202009%20WANG.

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18

鄧樹森 and Shu-sum Tang. "Cephalometric airway measurements in class III skeletal deformity." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B38628065.

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19

Au, Pui Ming. "Vibration of branched circular cylindrical shells as applied to airway walls a thesis submitted to Auckland University of Technology in fulfilment of the requirement for the degree of Doctor of Philosophy, March 2005." Full thesis. Abstract, 2005.

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20

Menon, Anilkumar S. "Flow dynamics in a model of the large airways." Thesis, McGill University, 1985. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=72009.

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Oscillatory velocity profiles and the pressure-flow relationship were measured in a 3:1 scale rigid model of the human central airways. A reciprocating pump provided flows with frequencies of 0.25, 1, 2 and 4 Hz and tidal volumes of 300, 500 and 1500 mL giving tracheal Womersley numbers up to 31 and peak tracheal Reynolds numbers up to 17000. A hot wire anemometer was used to measure velocities along two perpendicular diameters (one in the plane of the model and the other in the plane perpendicular to the model) at 10 stations distributed through the model. Velocities were also measured with a

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21

Izci, Bilgay. "Breathing during sleep : studies related to upper airway calibre in pregnancy." Thesis, University of Edinburgh, 2007. http://hdl.handle.net/1842/1971.

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Snoring is common in pregnancy, and has been associated with an increased incidence of both maternal hypertension and preeclampsia, as well as an increased incidence of low birth weight infants and significantly poorer Apgar scores at birth. Patients with pre-eclampsia have episodes of partial upper airway (UA) obstruction during sleep. These repeated episodes are associated with further increases in blood pressure (BP). Preliminary evidence indicates that preventing episodes of airflow obstruction with continuous positive airway pressure (CPAP) therapy may reduce BP in pre-eclampsia. Snoring

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22

Mackawan, Surussawadi. "The relationship between added lung sounds and airway dimensions." Thesis, University of Southampton, 2012. https://eprints.soton.ac.uk/354119/.

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The aim of this study was to explore potential relationships between added lung sound characteristics measured by Computer Aided Lung Sound Analysis (CALSA) and airway dimensions measured by High resolution Computed Tomography (HRCT). CALSA has been proposed as a new objective measurement to record and analyse lung sounds. However, there is still a lack of evidence as to whether and how added lung sounds relate to the geometry of airways. HRCT is considered to have the highest sensitivity of imaging measurements and is capable of generating three dimensional pictures of airways from which the

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23

Behndig, Annelie. "Airway antioxidant responses to oxidative air pollution and vitamin supplementation." Doctoral thesis, Umeå universitet, Folkhälsa och klinisk medicin, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-742.

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Air pollutants, such as ozone (O3) and diesel exhaust particles, elicit oxidative stress in the lung. Antioxidants within the respiratory tract lining fluid (RTLF) protect the underlying tissue from oxidative injury. Supplementation with vitamins has been shown to modulate the acute ozone-induced effects, but the mechanisms behind this have not been fully clarified. The aim of this thesis was to investigate the airway responses to diesel exhaust and ozone exposure in healthy humans, with the emphasis on inflammatory and antioxidant responses. Furthermore, to study whether oral supplementation

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24

Whicker, Susan D. "Pharmacological studies of [beta]-adrenoceptors in airway smooth muscle." Thesis, The University of Sydney, 1990. https://hdl.handle.net/2123/26279.

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Airway smooth muscle receptor-mediated responsiveness and receptor characteristics for airway tissue from non-asthmatic and asthmatic patients, and guinea pigs with airway responsiveness, were investigated for airway preparations using drug concentration-response relationships and radiolabelled ligand binding studies. Between—patient variability was approximately SSO-fold greater than within-patient variability for B-adrenoceptor-mediated responsiveness of human airway tissue. Alteration in B-adrenoceptor characteristics (Kd and Bmax) could not account for the marked between-patient vari

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25

Kelly, Clive Anthony. "The use of bronchoalveolar lavage in the investigation of the pathophysiology of airway hyperresponsiveness." Thesis, University of Newcastle Upon Tyne, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.329175.

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26

Armstrong, Julian. "Anatomical optical coherence tomography in the human upper airway /." Connect to this title, 2006. http://theses.library.uwa.edu.au/adt-WU2007.0022.

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27

Ramos-Barbón, David. "The role of CD4+T cells in airway remodeling in experimental asthma /." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=85640.

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The aim of this work was to investigate the role of CD4 + T cells, central to airway inflammation in asthma, in airway remodeling. Structural changes that occur in asthmatic airways in association with inflammation include an increase in airway smooth muscle mass, which participates in causing airway hyperresponsiveness. We aimed to gain further insights into the mechanisms that may link inflammation with remodeling using a rat model of experimental asthma. We hypothesized that CD4+ T cells drive airway smooth muscle remodeling. Adoptive transfer of CD4+ T cells from ovalbumin-sensitize

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28

Sobuwa, Simpiwe. "Prehospital airway management in severe closed traumatic brain injury an analysis of its impact on outcome." Master's thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/2873.

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Includes abstract.<br>Includes bibliographical references.<br>The purpose of this study was to describe the outcomes of patients with severe traumatic brain injury managed by emergency care providers in the Cape Town Metropole.

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29

Zheng, Ling 1958. "Airway inflammation and remodelling post human lung transplantation." Monash University, Dept. of Medicine, 2002. http://arrow.monash.edu.au/hdl/1959.1/8099.

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30

Li, Min. "Tobramycin Disposition in the Lung Following Airway Administration." VCU Scholars Compass, 2013. http://scholarscompass.vcu.edu/etd/3275.

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Tobramycin disposition following airway administration was evaluated by meta-analysis of human data in the literature and, experimentally, using a realistic ex vivo model, the isolated perfused rat lung preparation (IPRL). Pulmonary bioavailability of inhaled tobramycin in published studies was re-evaluated separately for CF and healthy adults, with the drug’s intrinsic pharmacokinetic (PK) parameters obtained from intravenous (IV) studies in the literature. While large variations in tobramycin’s clearance precluded accurate assessment of its bioavailability, the results were indicative of sub

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31

Chakravorty, Indranil. "Health technology assessment of continuous positive airway pressure devices in sleep apnoea hypopnoea syndrome." Thesis, University of Warwick, 2005. http://wrap.warwick.ac.uk/38056/.

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A. 1 Background The need to assess safety as well as clinical and economic effectiveness of health care innovations and thus prioritise health care provision, created the need for structured health technology assessment (HTA) programs [Gafni et al. 1993b; Henshall et al. 1997; Stevens et al. 20041. Sleep apnoea hypopnoea syndrome (SAHS) affects 2-4% of the adult population [Young et al. 1993] who are disabled by daytime dysfunction [Hardinge et al. 1995; Johns 1993b; Mitler 1993; Sauter et al. 200l and a heightened mortality and morbidity [Greenberg et al. 1995; Kiely et al. 2000; Peker et al.

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32

Laing, Ingrid A. "Candidate gene approach to investigating airway inflammation and asthma." University of Western Australia. School of Paediatrics and Child Health, 2005. http://theses.library.uwa.edu.au/adt-WU2005.0097.

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[Truncated abstract] Asthma genetic studies have identified many genes that contribute to the pathogenesis of asthma and related variables. Members of the secretoglobin family appear to play an important role in controlling airway inflammation but they have received relatively little attention in asthma genetic research. In this thesis, I have investigated the genes of two members of the secretoglobin family (16 kDa Clara cell secretory protein (CC16) and secretoglobin 3A2 (SCGB3A2)) that are expressed at high levels in the airways and are important anti-inflammatory agents. The overall aim of

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33

Haji, Sadeghi Mahboobeh. "The emerging role of the eosinophil and its measurement in chronic cough : airway inflammation in chronic cough." Thesis, University of Hull, 2017. http://hydra.hull.ac.uk/resources/hull:16543.

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Although the aetiology of chronic cough in guidelines is clearly stated as asthma and related syndromes, gastro-oesophageal reflux disease, and upper airways disease, the inflammatory mechanisms underlying these conditions differ. Recent studies on asthma have increasingly focused on its molecular phenotypes instead of clinical characteristics. Predominantly in this thesis I hypothesize that by dividing cough patients into the clinical characteristics of eosinophilic and neutrophilic groups will enhance our ability to recognise the type of airway inflammation, and consequently will lead us to

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34

Marino, Rafael. "Genetic dissection of airway responsiveness and its impact on the susceptibility to allergic asthma." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97030.

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Asthma is a chronic and inflammatory disease of the airways determined by genetic and environmental factors which trigger an uncontrolled immune response. Airway hyperresponsiveness (AHR) is inherited as a complex trait and associated with asthma. We assessed AHR in naïve A/J and C57BL/6J mice using the non-invasive method and demonstrated its correlation with invasive method evaluating AHR in non-sensitized mice. Aditionally, we studied the genetic causes underlying AHR using six F2 backcrosses generated from recombinant congenic strains (RCS) created from A/J and C57BL/6J parental strains. O

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35

Kitaev, Timur. "Evaluating Perceived Barriers to Cognitive Aid Use Among Anesthesia Providers During Malignant Hyperthermia, Myocardial Ischemia, and Unanticipated Difficult Airway." Thesis, University of Southern California, 2021. http://pqdtopen.proquest.com/#viewpdf?dispub=28002089.

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Background: A cognitive aid is defined by the Stanford Anesthesia Cognitive Aid Group as a visual in any form intended to enhance cognition and improve adherence to medical best practices. While the efficacy of cognitive aid use during simulated, intraoperative emergencies is well supported in the current literature, their use in anesthesia practice remains limited. Aim: The aim of this doctoral capstone paper is to investigate perceived barriers to cognitive aid use in the operating room among anesthesia providers during various emergency situations. Methodology: An anonymous survey was disse

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36

Chang, Michael K. "Three-dimensional conebeam CT analysis of pharyngeal airway changes after orthognathic surgery." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1465479.

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37

Leow, Li Pyn. "Mechanisms of airway protection in ageing and Parkinson's disease." Thesis, University of Canterbury. Communication Disorders, 2007. http://hdl.handle.net/10092/1461.

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Safe and efficient swallowing requires integrity of both motor and sensory systems. Prior studies have established that motor impairment in individuals with PD frequently manifests as abnormalities in swallowing biomechanics. In contrast, very few studies have investigated the contribution of sensory impairment towards pharyngeal biomechanics and airway protection in this patient cohort. This area should be addressed in light of evidence that the severity of limb motor dysfunction in PD does not reliably predict severity of dysphagia. Emerging data suggests that dysphagia in PD cannot be s

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38

Cunningham, Jason Owen. "Variation in airway remodelling genes and their role on asthma severity in children and young adults." Thesis, University of Sussex, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590080.

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Background: Asthma affects approximately 300 million people worldwide ', 5.2 million of these people live in the UK2, 1.1 million of these are children" Asthma is one of the most common chronic diseases and is the fourth leading cause of morbidity worldwide, and there is no indication of a decline in prevalence. It is hypothesised that a range of gene- environmental interactions may influence the susceptibility, severity and medication response of asthma in children and young adults". Methods: To explore these issues, two studies have been established to create datasets that will describe the

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39

Sikuvi, Kaveto Andreas. "The availability and perceived knowledge of use of airway management devices in emergency centres at referral hospitals in Namibia." Master's thesis, Faculty of Health Sciences, 2017. http://hdl.handle.net/11427/31225.

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Introduction Maintaining the airway is an essential element in the care of any ill or injured patient. Inadequate management of the airway may lead to hypoxia and hypercarbia with subsequent secondary brain injury, cardiopulmonary arrest, and ultimately death. The aim of the study was to identify which airway devices are available in public emergency centres of referral hospitals in Namibia and to determine the perceived level of knowledge of use regarding these devices. Methods A cross-sectional study was conducted in four emergency centres of referral hospitals in Namibia. Data regardi

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40

Chong, Mei-man, and 臧薇敏. "Three-dimensional comparison of the upper airway in various types of dentofacial deformities." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48542027.

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Objectives 1. To define the normative airway of Chinese population using three-dimensional imaging and computer analysis 2. To evaluate the upper airway differences in patients with normal facial profile and those with skeletal class III deformity 3. To evaluate the differences in upper airway models among patients with different dentofacial deformities and describe the role of computational fluid dynamics (CFD) in the human upper airway Materials and Methods Part I : Three-Dimensional Analysis of the Normative Upper Airway in Chinese This was a cross-sectional observational stu

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41

Pourazar, Jamshid. "Activation of epithelial signal transduction pathways, cytokine production and airway inflammation following diesel exhaust exposure." Doctoral thesis, Umeå : Department of Public Health and Clinical Medicine, Umeå University, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-795.

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42

Stolarski, Bartosz. "The role of IL 33/ST2 pathway in innate immune response in airway inflammation." Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/2961/.

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Asthma is a common and complex inflammatory disease of the airways characterized by deregulated immune responses that involves activation of multiple cell types including Th2 cells, IgE producing B cells, mast cells, basophils and eosinophils as well as resident lung cells such as epithelial, smooth muscle cells and macrophages. Despite intensive research, there are still unmet needs in the treatment of asthma. Recently, a new cytokine of IL 1 family, named IL 33 emerged as a potentially important factor in the immunopathogenesis of allergy and asthma. It was recently shown in our laboratory t

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Govindaraju, Vasanthi. "Actions of interleukin-8 and extracellular nucleotides on airway smooth muscle from normal and CF subjects." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=85553.

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Cystic fibrosis (CF) patients have airway neutrophilic inflammation associated with high levels of interleukin-8 (IL-8) and often develop airway hyperresponsiveness (AHR). Aerosolized uridine triphosphate (UTP) has been used to improve mucosal clearance by inducing Cl- secretion. However, nucleotides such as UTP and ATP (adenine triphosphate) also evoke the release of intracellular Ca2+ ([Ca2+]i), which are enhanced by pro-inflammatory mediators, such as IL-1beta. Since most of the CF airway epithelium is lost during infection and inflammation, the underlying airway smooth muscle cells

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Armstrong, Julian. "Anatomical optical coherence tomography in the human upper airway." University of Western Australia. School of Electrical, Electronic and Computer Engineering, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0022.

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[Truncated abstract] This thesis describes the development, clinical validation and initial application of a technique for taking measurements of the shape and dimensions of the human upper airway, called anatomical optical coherence tomography (aOCT). The technique uses a transparent catheter containing a rotating optical probe which is introduced transnasally and positioned in the airway and oesophagus. Optical coherence tomography is used to take calibrated cross-sectional images of the airway lumen as the probe rotates. The probe can also be advanced or withdrawn within the catheter during

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Craig, Daniel John. "Low Frequency Airway Epithelial Cell Mutation Pattern Associated with Lung Cancer Risk." University of Toledo Health Science Campus / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=mco1556918218571742.

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46

Castle, Nicholas. "What airway and vascular access skills can be performed whilst wearing the NHS issued chemical, biological, radiation, and nuclear personal protective equipment?" Thesis, City University London, 2014. http://openaccess.city.ac.uk/15163/.

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The introduction of chemical, biological, radiation and nuclear personal protective equipment (CBRN-PPE) across the National Health Service (NHS), in 2007, represented an increase in the capacity to treat patients following a CBRN incident. However, little was known on what impact the NHS CBRN-PPE would have on skill performance. To date a number of studies have evaluated various skills performed whilst wearing a range of CBRN-PPE, none of which resembles the NHS CBRN-PPE. This gap in the evidence prompted a series of research studies addressing the following research question, ‘What airway an

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Burke, Jan. "Prehospital advanced airway management practices by advanced life support providers: A retrospective observational study of emergency medical service providers in South Africa." Master's thesis, Faculty of Health Sciences, 2021. http://hdl.handle.net/11427/32596.

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Introduction: The skill of endotracheal intubation to achieve a definitive airway for critically ill and injured patients in the prehospital setting is frequently performed by advanced life support providers. Several methods may be utilised, including intubation without the use of medication, the use of sedatives or a rapid sequence intubation. There is a paucity of data available that assesses prehospital advanced airway intubation practices in South Africa. The aim of this study is to describe the advanced airway management practices of advanced life support providers across South Africa. Me

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48

Hotchkiss, Joel W. "Quantitative epidemiological studies on recurrent airway obstruction in the horse population of Great Britain using a risk-screening questionnaire." Thesis, University of Glasgow, 2004. http://theses.gla.ac.uk/2607/.

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The principal aim of this study was to investigate the epidemiology of recurrent airway obstruction (RAO) in horses in Great Britain using risk-screening questionnaires (RSQ). Three processes were used to aid construction of the RSQ for RAO, namely: a review of the scientific literature, a survey of equine practitioners in the UK and a modified Delphi consultation with experts in the field of RAO. The demographic information, generated by the questionnaire, enabled investigation of risk factors associated with the disease using multilevel, multivariable logistic regression. Two models were con

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49

Cameron, Euan John. "Effects of azithromycin on asthma control, airway inflammation and bacterial colonisation in smokers with asthma : a randomised control trial." Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/4575/.

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Smokers with asthma represent an important sub-group of asthmatics displaying both reduced response to inhaled and oral corticosteroids as well as demonstrating accelerated decline in lung function and increased use of health care services. Clinical and laboratory studies have suggested that macrolide antibiotics may exhibit anti-inflammatory properties in a variety of airways disease including asthma. The anti-inflammatory properties of macrolides have been recognised for almost 50 years. Indirect evidence from both pre-clinical and clinical studies suggests that the mechanism of action may b

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Hart, Matthew Thomas. "The Effects of Aerosol Drug Delivery on Airway Resistance through Heat-Moisutre Exchangers." Digital Archive @ GSU, 2009. http://digitalarchive.gsu.edu/rt_theses/4.

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Introduction: The use of heat moisture exchangers (HMEs) is becoming more popular with many institutions delivering aerosolized medications between the HME and the endotracheal tube of patients being mechanically ventilated. When HMEs become saturated resistance can increase which can cause changes that can lead to patient-ventilator dysnchrony, development of intrinsic PEEP, and weaning difficulty. The purpose of this study was to determine the effects of aerosol drug delivery on resistance through heat-moisture exchangers. Method: An in-vitro model to simulate exhaled heat and humidity from

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