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Relevant bibliographies by topics / Alchornea laxiflora

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Journal articles

Academic literature on the topic 'Alchornea laxiflora'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Alchornea laxiflora"

1

O. J., Ogunbiyi, Apata J. T., Jegede R. J., and Akinola F. T. "The Effects of Alchornea laxiflora Leaf Extract on Total- and HDL- Cholesterol Levels in Serum, Liver, and Kidney of Rats." Journal of Molecular Pharmaceuticals and Regulatory Affairs 4, no. 2 (2022): 15–19. http://dx.doi.org/10.46610/jmpra.2022.v04i02.003.

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Alchornea laxiflora is one of the underutilized tropical plants in Nigeria. The extract from the leaf has been shown to contain certain phytochemical principles which have been linked to some of its medicinal uses. The effect of Alchornea laxiflora aqueous leaf extract on the level of the total- and high-density lipoprotein (HDL) - cholesterols in the serum, liver, and kidney of rats was evaluated in this study. Twelve rats were grouped into three containing four each. Group A (control) was administered with only distilled water. Groups B and C were administered with aqueous extract of Alchorn

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2

Uhunmwangho, Esosa Samuel, Olajide Nurudeen Rasaq, and Onoriode Oyiborhoro. "Antioxidant Actions of Freshly Commuted Hexane Extracts of Alchornea Laxiflora Root on Sodium- Arsenate Induced Oxidative Stress in Male Wistar Rats." Research and Analysis Journal 4, no. 11 (2021): 21–25. http://dx.doi.org/10.18535/raj.v4i11.247.

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The antioxidant activities of hexane extract of freshly commuted roots (HR) of Alchornea laxiflora on liver damage were examined using in vivo sodium arsenate-induced oxidative damage model in male Wistar rats weighing between 150 and 200 g. The animals were grouped into two groups of four animals, group 1 animals were given 1ml of sodium-arsenate (2mg/kg) for 2 days and then treated with graded dosage (0.5, 1.0, 5.0 and 10.0 mg/kg body weight) HR of Alchornea laxiflora for 10days, while group 2 animals were given the same graded dosage HR extract of Alchornea laxiflora for 10 days but in addi

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3

Ogundipe, O. O., J. O. Moody, and P. J. Houghton. "Occurrence of Flavonol Sulphates in Alchornea laxiflora." Pharmaceutical Biology 39, no. 6 (2001): 421–23. http://dx.doi.org/10.1076/phbi.39.6.421.5888.

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4

Okokon, Jude E., Anwangabasi E. Udoh, Chinyelu Clementina Osigwe, Ugonma Florence Uwaeme, and Henry Thomas Okon. "Analgesic Activity of Alchornea laxiflora Stembark Extract in Mice." Asian Journal of Biochemistry, Genetics and Molecular Biology 17, no. 6 (2025): 22–29. https://doi.org/10.9734/ajbgmb/2025/v17i6470.

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Alchornea laxiflora is used in Ibibio ethnomedicine for the treatment of various diseases such as pains. This work was designed to validate and confirm the ethnomedical use of this plant in the treatment of pain. The ethanol stembark extract of Alchornea laxiflora (141-424 mg/kg) was evaluated for analgesic activity against experimentally-induced pains in mice using acetic acid-induced writhing, formalin-induced hind paw licking and thermally-induced pain models. The stembark extract significantly (p<0.005-0.001) inhibited pains in all the models tested in a dose-dependent manner. The extra

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5

Jain, Nem Kumar, Balakumar Chandrasekaran, Nasha’t Khazaleh, et al. "Computational Network Pharmacology, Molecular Docking, and Molecular Dynamics to Decipher Natural Compounds of Alchornea laxiflora for Liver Cancer Chemotherapy." Pharmaceuticals 18, no. 4 (2025): 508. https://doi.org/10.3390/ph18040508.

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Background: Alchornea laxiflora (Benth.) Pax & K. Hoffm. (A. laxiflora) is utilized as a traditional herb for treating several diseases. Objective: Our study aims to identify the active phytochemical candidates from A. laxiflora and analyses to predict their anticancer activity mechanism by employing network pharmacology, molecular docking, and molecular dynamics (MD). Methods: The phytoconstituents of A. laxiflora were retrieved from the literature, and phytoconstituent-related targets implicated in hepatocellular carcinoma (HCC) were collected from respective databases. Computational met

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6

K. Oloyede, Ganiyat, Patricia A. Onocha, Oluwatosin A. Adaramo, and S. Emmanuel Thonda. "Hepatoprotective Activity and Flavonoids of Alchornea laxiflora Leaf Extract." Research Journal of Phytochemistry 5, no. 4 (2011): 190–200. http://dx.doi.org/10.3923/rjphyto.2011.190.200.

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7

Durojaye, Catherine, Olusola Elekofehinti, Innocent Osho, and Stephen Abodunrin. "Alchornea laxiflora as therapeutic agent in the treatment of Trypanosoma brucei brucei infection using experimental wistar rats; invivo and gene expression studies." Journal of Research in Veterinary Sciences 1, no. 1 (2023): 27. http://dx.doi.org/10.5455/jrvs.20230812093455.

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Aims: African trypanosomosis is a zoonotic tropical disease of Sub-Saharan Africa. Its etiology is a group of extracellular protozoans of the genera Trypanosoma which has numerous species including Trypanosoma brucei brucei. Inavailability of vaccines and numerous side effects arising from few available antitrypanosomal drugs gives the indication for search for local alternatives. This experimental study investigates the antitrypanosomal efficacy of chloroform extract of A. laxiflora leaves in wistar albino rats infected with Trypanosoma brucei brucei. Place and Duration of Study: Animal Paras

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8

Nwonu, Chukwunwike, Olapade Ilesanmi, Joseph Agbedahunsi, and Patience Nwonu. "Analgesic Profile of the Aqueous and Methanol Extracts of Alchornea Laxiflora in Albino Mice." European Scientific Journal, ESJ 14, no. 24 (2018): 134. http://dx.doi.org/10.19044/esj.2018.v14n24p134.

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The study investigated the median lethal dose and the effects of the aqueous and methanol extracts of Alchornea laxiflora in three mouse models of central and peripheral analgesia, the hot plate, acetic acid-induced abdominal writhes and the tail immersion tests. This was with a view to providing information on the acute toxicity, analgesic effects and the possible mechanism of analgesia. The LD50 for the aqueous and methanol extracts of A. laxiflora in the oral route was > 1600 mg/kg respectively, and found to be safe in animals. However, the LD50 (i.p.), was found to be 400 mg/kg for the

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9

Okokon, Jude E., Aniedi U. Obot, Dinesh Mohanakrishnan, Garima Mittal, and Dinkar Sahal. "Antimalarial and Antiplasmodial Activity of Leaf Extract of Alchornea laxiflora." Journal of Herbs, Spices & Medicinal Plants 23, no. 2 (2017): 128–41. http://dx.doi.org/10.1080/10496475.2016.1275072.

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10

Ogundipe, O. O., J. O. Moody, P. J. Houghton, and H. A. Odelola. "Bioactive chemical constituents from Alchornea laxiflora (benth) pax and hoffman." Journal of Ethnopharmacology 74, no. 3 (2001): 275–80. http://dx.doi.org/10.1016/s0378-8741(00)00352-4.

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